CN109730662A - Physiology physical sign monitoring system based on multispectral pulse wave - Google Patents
Physiology physical sign monitoring system based on multispectral pulse wave Download PDFInfo
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Abstract
The present invention relates to a kind of physiology physical sign monitoring system based on multispectral pulse wave, the physiology physical sign monitoring system based on multispectral pulse wave includes hardware components, software section and algorithm part, belongs to integrated solution；The hardware components comprise the following modules: control unit, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply unit；The light source unit supports the light source of at least four wave band；The processing unit is used for signal processing；The wireless transmission unit can be transmitted for Bluetooth transmission or WIFI；The power supply unit is battery or rechargeable；The physical signs that the software section calculates includes heart rate and heart rate variability；Respiratory rate；Blood oxygen saturation；Blood pressure/blood pressure.Its advantage is shown: can be applicable to can pass through multispectral pulse wave signal and monitor multiple physical signs simultaneously, and provide clinical meaning in portable wearable device；Enhance the stability and robustness of single physical signs monitoring.
Description
Technical field
The present invention relates to multispectral technical fields, specifically, being a kind of physiology sign prison based on multispectral pulse wave
Examining system.
Background technique
As China enters the aging society stage gradually, all kinds of Aging Problems are constantly highlighted, the health of the aged
Problem is exactly wherein one of urgent problem to be solved.Gradually due to patient populations dead because suffering from blood vessel tubing disease every year
Rise, has become the whole society, in particular for the great public health problem of the elderly.Thus, in order to realize painstaking effort
The prevention and adjuvant treatment of tubing disease, there is an urgent need to carry out continuous monitoring to physiologic informations such as pulse, blood pressure and electrocardios.
Currently used and more mature wearable physiology continuous monitoring product is mostly two classes: (1) motion bracelet,
By single green band, come monitor heart rate signal, (green light band PPG signal is strong, can reach certain motion robustness, but supervise
The physical signs of survey is excessively single)；(2) finger oximeters are saturated by red and infrared double-waveband come monitor heart rate and blood oxygen
It spends (infrared band PPG signal is weak, therefore rhythm of the heart stability is lower).
Chinese patent literature: CN201710805700.1, applying date 2017.09.08, patent name are as follows: be based on PPG pulse
Monitoring of blood pressure sensor chip of wave and preparation method thereof.Disclose a kind of monitoring of blood pressure sensor core based on PPG pulse wave
Piece and preparation method thereof comprising: substrate, the flexible media layer being arranged on substrate, the drain-source being arranged on flexible media layer
Electrode, gate electrode and electrocardio measuring electrode, drain-source electrodes, gate electrode and electrocardio measuring electrode are respectively positioned on flexible media layer
On；The active layer being arranged on the interdigitated region of drain-source electrodes, on active layer and is not covered on the region of active layer
The protective layer of setting.
Chinese patent literature: CN201610599137.2, applying date 2016.07.27, patent name are as follows: a kind of optics is swept
Retouch formula pulse wave sensor and wearable device.Disclose a kind of optical scanner formula pulse wave sensor and wearable device, light
Learn scan-type wrist type pulse wave analyzer, optical scanner formula heart rate monitor, optical scanner formula blood pressure monitor, optical scanner formula blood vessel
Hardness analyzer, optical scanner formula carotid artery stiffness analyzer and pulse wave monitoring method.The pulse wave sensor includes laser
Transmitter emits first laser；Branch optical waveguide component, receives first laser and branch is second laser and reference light；Light draws
Output block is led, receive and adjusts second laser to form third laser, third laser is enable to be incident on blood vessel；Light guidance is defeated
Enter component, receive and adjusts the 4th laser from vasoreflex to form the 5th laser；Receiving light path component receives the 5th laser
The 6th laser is formed after two-way is interfered with reference light.
A kind of monitoring of blood pressure sensor chip and preparation method thereof based on PPG pulse wave of above patent document, blood pressure
Monitor sensor chip can long-term seamless applying human body, while measuring electrocardiosignal and pulse wave of multiple points, realize noninvasive company
Continuous monitoring of blood pressure, and preparation method simplifies preparation process using the whirl coating technique and inkjet printing technology of low cost；And it is special
One of sharp document CN201610599137.2 optical scanner formula pulse wave sensor and wearable device, the then one kind provided
Optical scanner formula pulse wave sensor, related monitoring device and wearable device are able to achieve continuous monitoring, and accuracy is high, effect is good
And it is low in energy consumption.But a variety of different physical signs can be monitored by different light source wave bands simultaneously about a kind of, and enhance single
The stability and robustness of a physical signs monitoring, and have and a kind of physiology based on multispectral pulse wave of clinical meaning is provided
Physical sign monitoring system is at present then without relevant report.
In conclusion needing a kind of by different light source wave bands, a variety of different physical signs can be monitored simultaneously, and increase
The stability and robustness of strong single physical signs monitoring, and have and a kind of based on multispectral pulse wave of clinical meaning is provided
Physiology physical sign monitoring system.
Summary of the invention
It is a kind of by different light source wave bands the purpose of the present invention is aiming at the shortcomings in the prior art, providing, it can be simultaneously
A variety of different physical signs are monitored, and enhance the stability and robustness of single physical signs monitoring, and have and clinic is provided
A kind of physiology physical sign monitoring system based on multispectral pulse wave of meaning.
To achieve the above object, the technical solution adopted by the present invention is that:
A kind of physiology physical sign monitoring system based on multispectral pulse wave, which is characterized in that described based on multispectral arteries and veins
The physiology physical sign monitoring system of wave of fighting includes hardware components, software section and algorithm part；The hardware components include: control
Unit, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply unit；The light source unit branch
Hold the light source of at least four wave band；The processing unit is used for signal processing；The wireless transmission unit be Bluetooth transmission or
WIFI transmission；The power supply unit is battery or rechargeable.
As a kind of perferred technical scheme, the light source unit of the control unit timing control different-waveband, simultaneously
Including visible light and black light part；The light source of different-waveband successively emits optical signal, and light signal collection unit successively acquires
Optical signal, and it is sent to processing unit；Processing unit handles optical signal, and control unit, control unit are transmitted to after processing
The result of processing is transmitted to terminal device by wireless transmission outward；Wherein, processing unit can directly extract physical signs transmission
To terminal, or carries out simple Signal Pretreatment and be then forwarded to terminal extraction physical signs.
As a kind of perferred technical scheme, the physical signs that the software section calculates, required wave band and calculating
Correlated characteristic is as follows:
Heart rate and heart rate variability: blue light, green light band；PPG signal frequency domain [40,240] hertz peak detection；
Respiratory rate: blue light, green light band；PPG signal frequency domain [15,50] hertz peak detection；
Blood oxygen saturation: feux rouges, infrared band；The variation detection of PPG signal Time Domain Amplitude；
Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection.
The invention has the advantages that:
1, by different light source wave bands, a variety of different physical signs can be monitored simultaneously.
2, enhance the stability and robustness of single physical signs monitoring.
3, it can be applied in portable wearable device, multiple physical signs monitored simultaneously by multispectral pulse wave signal,
And provide clinical meaning.
Detailed description of the invention
Attached drawing 1 is a kind of structural representation of the physiology physical sign monitoring system hardware components based on multispectral pulse wave of the present invention
Figure.
Specific embodiment
It elaborates with reference to the accompanying drawing to specific embodiment provided by the invention.
Before illustrating the present invention, first illustrate the cardinal principle and thought of the present invention herein:
Multispectral photoplethysmographic (Multi-wavelength Photoplethysmography) can supervise simultaneously
Survey the pulse wave signal (PPG) under different light source wave bands；The pulse wave of different-waveband can reflect different human body physiological characteristics,
As the heart rate signal of green light band is most strong but to the variation of blood oxygen it is insensitive, infrared band is sensitive to the variation of blood oxygen but heart rate is believed
It is number faint；Therefore, PPG signal is extracted jointly under (visible light and black light) under multiple wave bands to be of great importance；It can be
Different physical signs is obtained under different-waveband, and can speculate more physiological characteristics in conjunction with the PPG signal of different-waveband,
The transmission time (Pulse Transit Time) of pulse wave, Jin Erji are such as speculated by the PPG signal under blue light and infrared light
Calculate blood pressure；
Physiological characteristic based on multispectral pulse wave detects feature are as follows: the physical signs monitoring (7 of wearable continuous non-invasive
It/24 hours)；It can monitor a variety of physical signs, such as heart rate simultaneously, heart rate variability, respiratory rate, blood oxygen saturation, blood pressure/
Blood pressure, etc.；
Multiple physical signs based on monitoring carry out intelligence in conjunction with artificial intelligence (machine learning/pattern-recognition/big data)
Diagnosis and alarm, such as predict different sleep stages by two indexs of heart rate variability and respiratory rate；
As monitoring side, the physiological status (forming personalized log) of long-term follow patient assists diagnosis and design
Targeted therapeutic scheme, or input/foundation is provided for therapeutic intervention equipment；
The technology is suitable for following scene:
Professional medical equipment；Long-continued physiology monitoring and report, such as cardiovascular disease, the heart are carried out for certain class patient
Pulmonary dysfunction/rehabilitation, hypertension, insomnia, OSAS, diabetes, Intensive Care Therapy (ICU), neonatal care (NICU), etc.；
Domestic healthy equipment；There is provided physiology monitoring for certain class special population or under special scenes, as the elderly (prevention,
Early warning), sub-health population, pilot/astronaut training (psychology/mood monitoring and management), training athlete/rehabilitation, security protection
Field (portable wearable a lie detector), cardiovascular disease, cardio-pulmonary function impaired patients follow-up, or have the group of related needs；
Attached drawing 1 is please referred to, Fig. 1 is a kind of physiology physical sign monitoring system hardware components based on multispectral pulse wave of the present invention
Structural schematic diagram.A kind of physiology physical sign monitoring system based on multispectral pulse wave, it is described based on multispectral pulse wave
Physiology physical sign monitoring system includes hardware components, software section and algorithm part, belongs to integrated solution；The hardware
Part comprises the following modules: control unit, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply
Unit；The light source unit supports the light source of at least four wave band；The processing unit is used for signal processing；The nothing
Line transmission unit can transmit for Bluetooth transmission or WIFI；The power supply unit is battery or rechargeable；
The groundwork process of the hardware components are as follows: (1) light source unit of control unit timing control different-waveband is (same
When include visible light and black light part), the light source of (2) different-waveband successively emits optical signal, light signal collection unit according to
Secondary acquisition optical signal, and it is sent to processing unit, (3) processing unit handles optical signal, control unit is transmitted to after processing,
The result of processing is transmitted to terminal device by being wirelessly transferred (bluetooth or WIFI) by control unit outward；Wherein, processing unit can
Directly extract physical signs and be sent to terminal, or carry out simple Signal Pretreatment be then forwarded to terminal extract physical signs (can
Undertake higher computation complexity)；
The correlated characteristic of the physical signs that the software section calculates, required wave band and calculating is as follows:
Heart rate and heart rate variability: blue light, green light band.PPG signal frequency domain [40,240] hertz peak detection；
Respiratory rate: blue light, green light band；PPG signal frequency domain [15,50] hertz peak detection；
Blood oxygen saturation: feux rouges, infrared band；The variation detection of PPG signal Time Domain Amplitude；
Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection；
It should be understood that mainly being had using the reason of multispectral detection pulse wave: (1) since the light of different wave length penetrates
The depth of skin is different, and the PPG signal acquired under different-waveband can reflect the information of different depth vescular bed；Such as blue light
(470nm) reflection be shallow-layer vein blood vessel information, and infrared (940nm) reflection be deep artery blood vessel information, this
The PPG signal phase difference in time of acquisition simultaneously under two wave bands；Therefore, the PPG signal meter under blue light and infrared light can be used
The transmission time of pulse wave is calculated, and then derives velocity of blood flow, blood pressure or even pressure value (needing baseline calibration)；(2) blood
Hemoglobin is different to the absorption of the light of different-waveband in liquid, the light of the oxygen content (HbO2, Hb) of hemoglobin to different-waveband
Sensibility it is also different；Pulse such as green light (570nm) wave band is most strong to the absorption of light, and red (660nm) and infrared
(940nm) changes blood oxygen most sensitive.Therefore different physical signs can be obtained simultaneously in conjunction with the PPG signal of different-waveband；
(3) it when calculating physical signs, can also mutually be supported between the PPG signal of different-waveband, it is common to cooperate, it is such as full in calculating blood oxygen
Noise reduction is filtered to infrared PPG signal (signal is weaker) with blue light/green light PPG signal (signal is stronger) with when spending, is enhanced
Correlated characteristic.
Physiology sign detection system based on multispectral pulse wave of the invention can be simultaneously by different light source wave bands
Monitor a variety of different physical signs；Enhance the stability and robustness of single physical signs monitoring；This monitoring system can be applied
In in portable wearable device, multiple physical signs are monitored simultaneously by multispectral pulse wave signal, and provide clinical meaning.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
Member, under the premise of not departing from the method for the present invention, can also make several improvement and supplement, these are improved and supplement also should be regarded as
Protection scope of the present invention.
Claims (3)
1. a kind of physiology physical sign monitoring system based on multispectral pulse wave, which is characterized in that described based on multispectral pulse
The physiology physical sign monitoring system of wave includes hardware components, software section and algorithm part；The hardware components include: that control is single
Member, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply unit；The light source unit is supported
The light source of at least four wave band；The processing unit is used for signal processing；The wireless transmission unit be Bluetooth transmission or
WIFI transmission；The power supply unit is battery or rechargeable.
2. the physiology physical sign monitoring system according to claim 1 based on multispectral pulse wave, which is characterized in that described
The light source unit of control unit timing control different-waveband, while including visible light and black light part；The light of different-waveband
Source successively emits optical signal, and light signal collection unit successively acquires optical signal, and is sent to processing unit；Processing unit believes light
It number is handled, control unit is transmitted to after processing, the result of processing is transmitted to terminal outward by wireless transmission and set by control unit
It is standby；Wherein, processing unit can directly extract physical signs and be sent to terminal, or carries out simple Signal Pretreatment and be then forwarded to end
Extract physical signs in end.
3. the physiology physical sign monitoring system according to claim 1 based on multispectral pulse wave, which is characterized in that described soft
The correlated characteristic of the physical signs that part part calculates, required wave band and calculating is as follows:
Heart rate and heart rate variability: blue light, green light band；PPG signal frequency domain [40,240] hertz peak detection；
Respiratory rate: blue light, green light band；PPG signal frequency domain [15,50] hertz peak detection；
Blood oxygen saturation: feux rouges, infrared band；The variation detection of PPG signal Time Domain Amplitude；
Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection.
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| CN110251094A (en) * | 2019-05-14 | 2019-09-20 | 周常安 | Finger-worn type physiology detection apparatus |
| CN110367960A (en) * | 2019-07-29 | 2019-10-25 | 泉州师范学院 | A kind of physiologic information monitoring system for crewman's rescue |
| CN113576435A (en) * | 2021-09-10 | 2021-11-02 | 湖南金智芯医疗科技有限公司 | Preparation method of nano chip integrating pulse wave, blood oxygen, heat metabolism and spectrum |
| CN114041762A (en) * | 2021-12-06 | 2022-02-15 | 汉朗科技(北京)有限责任公司 | Wearable device and method for monitoring underwater human body signs |
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| CN205433662U (en) * | 2015-12-23 | 2016-08-10 | 中国医学科学院生物医学工程研究所 | Sleep respiratory rate monitoring devices based on photoelectricity volume pulse ripples |
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Application publication date: 20190510 Assignee: Perth Sleep Technology (Shenzhen) Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2019980000225 Denomination of invention: Physiological sign monitoring system based on multispectral pulse wave License type: Exclusive License Record date: 20190930 |
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