CN109700962A - The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds - Google Patents

The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds Download PDF

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CN109700962A
CN109700962A CN201910209059.4A CN201910209059A CN109700962A CN 109700962 A CN109700962 A CN 109700962A CN 201910209059 A CN201910209059 A CN 201910209059A CN 109700962 A CN109700962 A CN 109700962A
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parts
clouds
gallus domesticlus
domesticlus brisson
materia medica
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谭本杰
杨素芳
葛洪伟
缪微微
韩杰
王鹏飞
李凤生
张倩雲
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Guangxi University
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Guangxi University
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Abstract

The invention discloses a kind of Chinese materia medica preparations for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds comprising 35~40 parts of Schisandra chinensis, 25~30 parts of radix pseudostellariae, 25~30 parts of Semen Nelumbinis, 25~30 parts of Rhizoma Gastrodiae, 25~30 parts of Longstamen Onion Bulb, 15~20 parts of the dried immature fruit of citron orange, 15~20 parts of rhizoma atractylodis, 7~15 parts of citron, 7~15 parts of myrobalan, 3~6 parts of betel nut, 3~6 parts of rhizoma acori graminei, 3~6 parts of fructus amomi.Chinese materia medica preparation of the invention has the advantage that pure Chinese medicinal preparation, and medicinal peace is nonirritant to chicken;Effectively preventing all kinds of intestines problems of Gallus domesticlus brisson of reaching the clouds, the especially incidental Escherichia coli of the kind, salmonella, necrotic enteritis has good control efficiency, improves the Growth Results for Gallus domesticlus brisson of reaching the clouds.

Description

The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds
Technical field
The present invention relates to field of animal, specifically prevent and treat the Chinese materia medica preparation for Gallus domesticlus brisson intestines problem of reaching the clouds.
Background technique
Gallus domesticlus brisson reach the clouds because its beak, hat, shin, toe, skin are in corvinus, referred to as " five Gallus domesticlus brissons ", there is preferable edible and medicine With value, it is the piece plumage native chicken breed of China's preciousness, China is regarded as by the national Genetic Resources of Domestic Animal committee in 2012 Native chicken breed.Area of reaching the clouds is located in Baise of Guangxi remote mountain areas, and traffic is extremely inconvenient, and information more occludes, thus reaches the clouds Gallus domesticlus brisson is not developed and used well for a long time.Gallus domesticlus brisson of reaching the clouds is easy to fall ill compared to other chickens, in terms of having gene Reason, shin, the toe for Gallus domesticlus brisson of reaching the clouds are corvinuses, shin, toe compared to yellow, and black color is recessiveness to yellow, by recessive gene control System, and the recessive gene of most of species is deleterious gene, the recessive gene that a biology carries is more, and premunition is poorer. During broiler breeding, it was also found that in same henhouse, identical age in days is fed with identical method by identical poultry raiser Shin, toe be corvinus chicken and shin, toe be yellow chicken, the former growth performance, survival rate will be far below the latter.In addition to heredity Factor, there are also factor of natural environment, Baise regional day and night temperature that reaches the clouds is larger, the April in especially annual November to second year, Day and night temperature is up to more than ten DEG C, and since day and night temperature is larger, the steam in air is easy to agglutination on padding, feed surface, Humidity is very big in giving up, and forms advantage to the breeding and propagation of pathogen.In this environment, chicken group is easy to big Enterobacteria, the enteron aisles class disease such as necrotic enteritis.Therefore, it is necessary to the medicines that one kind can effectively prevent Gallus domesticlus brisson intestines problem of reaching the clouds Object.
Summary of the invention
It is an object of the invention to solve at least the above problems, and provide the advantages of at least will be described later.
It is a still further object of the present invention to provide the Chinese materia medica preparations for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.The present invention be directed to insult The hereditary capacity of cloud Gallus domesticlus brisson and Baise reach the clouds area natural environment feature, design a kind of Chinese traditional compound medicine, effectively prevent icepro The intestines problem of cloud Gallus domesticlus brisson improves the cultivation profit for Gallus domesticlus brisson of reaching the clouds.Chinese materia medica preparation of the invention be by crushing, freeze thawing broken wall, The links such as organic extraction, stirring concentration are prepared.Chinese materia medica preparation of the invention has the advantage that pure Chinese medicinal preparation, pharmacological property It is gentle, it is nonirritant to chicken;Effectively prevent the incidental large intestine bar of all kinds of intestines problems of Gallus domesticlus brisson of reaching the clouds, the especially kind Bacterium, salmonella, necrotic enteritis have good control efficiency, improve the Growth Results for Gallus domesticlus brisson of reaching the clouds;Chinese medicine passes through freeze thawing It is refined with organic extraction techniques, the recovery rate of effective component is obviously improved, and efficacy stability, persistent.
In order to realize these purposes and other advantages according to the present invention, provides and prevent and treat in Gallus domesticlus brisson intestines problem of reaching the clouds Medicine preparation, the raw material including following parts by weight:
35~40 parts of Schisandra chinensis, 25~30 parts of radix pseudostellariae, 25~30 parts of Semen Nelumbinis, 25~30 parts of Rhizoma Gastrodiae, 25 ~30 parts of Longstamen Onion Bulb, 15~20 parts of the dried immature fruit of citron orange, 15~20 parts of rhizoma atractylodis, 7~15 parts of citron, 7~15 parts of myrobalan, 3~6 parts Betel nut, 3~6 parts of rhizoma acori graminei, 3~6 parts of fructus amomi.
Preferably, further include the raw material of following parts by weight:
10~20 parts of ginseng, 10~15 parts of cloud Siberian cocklebur, 5~10 parts of Divine Comedy, 5~10 parts of radix polygonati officinalis, 5~10 parts of life Glutinous rehmannia, 1~5 part of the fruit of glossy privet.
Preferably, comprising the following steps:
Step 1: by Schisandra chinensis, radix pseudostellariae, Semen Nelumbinis, Rhizoma Gastrodiae, Longstamen Onion Bulb, the dried immature fruit of citron orange, rhizoma atractylodis, citron, myrobalan, betel nut, stone Chang Pu, fructus amomi are ground into the medicinal powder of 100 mesh after being cleaned and dried, medicinal powder is stirred into paste according to said ratio and drinking water, and Temperature is freezed under conditions of being -25 DEG C and is taken out afterwards for 24 hours, obtains the first mixture in 25 DEG C of at a temperature of defrosting;
Step 2: the first mixture is mixed with the ethanol solution that volume fraction is 95% according to mass ratio 1:3, in room temperature Filtered after lower extraction 3h, repeat filter 3 times after merge obtains filtrate, to filtrate carry out vacuum distillation until concentration be clear cream after with Silica is uniformly mixed with mass ratio 1:3, and re-dry to moisture content obtains crude product for 5%;
Step 3: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, obtain The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.
Preferably, after the first mixture being made by step 1, before being mixed with the ethanol solution that volume fraction is 95%, also It joined the second mixture, the mass ratio of the first mixture and the second mixture is 1:10, and the second mixture is by following steps system :
S1, take the ginseng of above-mentioned parts by weight be sequentially placed into 90 parts, 60 parts, decocted in 30 parts of water, the duration of decoction It is followed successively by 2.5h, 2h, 1.5h, decoction liquor is obtained after 3 parts of liquid remaining after decoction is merged, first decoction liquor was carried out Filter, then ethyl alcohol that 50 parts of volume fractions are 75% is added into decoction liquor and is sufficiently stirred, it filters, is used in combination again after standing for 24 hours The ethyl alcohol that volume fraction is 60% carries out washing until colourless to decoction liquor, stands after 100 parts of water are added, obtains mixed liquor I;
S2, the cloud Siberian cocklebur of above-mentioned parts by weight, Divine Comedy, radix polygonati officinalis, radix rehmanniae recen, the fruit of glossy privet are shredded, and sequentially adds 50 thereto Part, 30 parts of water simultaneously successively decoct 2h, 1.5h, and the ethyl alcohol that 30 parts of volume fractions are 75% is added after collecting decoction and is simultaneously sufficiently stirred Obtain mixed liquor, refrigeration is filtered afterwards for 24 hours, then ethyl alcohol that volume fraction is 75% is added thereto and is sufficiently stirred, after standing 20h It is stood after 50 parts of water stirrings are added, obtains mixed liquor I I;
S3, the first mixture in mixed liquor I I made from mixed liquor I made from S1, S2, step 2 is mixed to get the Two mixtures.
Preferably, it is 18~30 DEG C that preparation, which prevents and treats the ambient temperature range of the Chinese materia medica preparation for Gallus domesticlus brisson intestines problem of reaching the clouds, Envionmental humidity range is 30%~70%.
Preferably, in step 2, the pressure condition of vacuum distillation is 4.2kPa.
The present invention is include at least the following beneficial effects:
The Chinese materia medica preparation that the present invention designs be directed to reach the clouds Gallus domesticlus brisson hereditary capacity and Baise reach the clouds area natural climate item Part, Gallus domesticlus brisson of reaching the clouds hold the type and feature of explosive group's intestines problem, and one kind of design is specifically for Gallus domesticlus brisson enteron aisle disease of reaching the clouds The pure Chinese medicinal preparation of disease prevention and treatment, can effectively prevent the intestines problem for Gallus domesticlus brisson of reaching the clouds.The present invention is pure Chinese medicinal preparation, medicinal peace, It is nonirritant to chicken;The intestines problem for Gallus domesticlus brisson of reaching the clouds is effectively prevented, especially the incidental a variety of enteron aisle class diseases of the kind There is good control efficiency, improves the Growth Results for Gallus domesticlus brisson of reaching the clouds;Chinese medicine is refined by freeze thawing and organic extraction techniques, effectively The recovery rate of ingredient is obviously improved, and efficacy stability, persistent.
The present invention can not only effectively prevent the intestines problem for Gallus domesticlus brisson of reaching the clouds, additionally it is possible to improve the immunity for Gallus domesticlus brisson of reaching the clouds, drop The feed-weight ratio of low Gallus domesticlus brisson of reaching the clouds enhances the constitution for Gallus domesticlus brisson of reaching the clouds, and increases its weight while reducing the The dead quantity of chicken, makes to insult Cloud Gallus domesticlus brisson has higher market value, and the formula of the second intermediary is free of antibiotics synthetic drug, to Gallus domesticlus brisson laying hen of reaching the clouds Laying rate is significantly improved, and the ratio of eggshell soft egg shell egg can be effectively reduced brokenly.It will not be to edible Gallus domesticlus brisson of reaching the clouds Crowd has an impact, and the raw material in S1 is ginseng, it is therefore desirable to decoction liquor is repeatedly decocted and collected to it, and for raw material in S2 Be easier to be made compared to ginseng, therefore decoction after fully smash and grind to it.
Further advantage, target and feature of the invention will be partially reflected by the following instructions, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.
Specific embodiment
The present invention will be further described in detail below with reference to the embodiments, to enable those skilled in the art referring to specification Text can be implemented accordingly.
<embodiment 1>
Step 1: by 35 portions of Schisandra chinensis, 25 parts of radix pseudostellariaes, 25 parts of Semen Nelumbinis, 25 parts of Rhizoma Gastrodiaes, 25 parts of Longstamen Onion Bulbs, 15 parts of dried immature fruit of citron oranges, The medicine of 100 mesh is ground into after 15 parts of rhizoma atractylodis, 7 portions of citrons, 7 parts of myrobalans, 3 portions of betel nuts, 3 parts of rhizoma acori gramineis, 3 parts of fructus amomis cleaning-dryings Medicinal powder and drinking water are stirred into paste, and freeze under conditions of temperature is -25 DEG C and take out afterwards for 24 hours by powder, in 25 DEG C of temperature Lower defrosting obtains the first mixture;
Step 2: the first mixture is mixed with the ethanol solution that volume fraction is 95% according to mass ratio 1:3, in room temperature Filtered after lower extraction 3h, repeat filter 3 times after merge obtains filtrate, to filtrate carry out vacuum distillation until concentration be clear cream after with Silica is uniformly mixed with mass ratio 1:3, and re-dry to moisture content obtains crude product for 5%;
Step 3: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, obtain The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.
<embodiment 2>
Step 1: by 37 portions of Schisandra chinensis, 27 parts of radix pseudostellariaes, 28 parts of Semen Nelumbinis, 27 parts of Rhizoma Gastrodiaes, 26 parts of Longstamen Onion Bulbs, 17 parts of dried immature fruit of citron oranges, The medicine of 100 mesh is ground into after 18 parts of rhizoma atractylodis, 10 portions of citrons, 10 parts of myrobalans, 5 portions of betel nuts, 5 parts of rhizoma acori gramineis, 5 parts of fructus amomis cleaning-dryings Medicinal powder and drinking water are stirred into paste, and freeze under conditions of temperature is -25 DEG C and take out afterwards for 24 hours by powder, in 25 DEG C of temperature Lower defrosting obtains the first mixture;
Step 2: the first mixture is mixed with the ethanol solution that volume fraction is 95% according to mass ratio 1:3, in room temperature Filtered after lower extraction 3h, repeat filter 3 times after merge obtains filtrate, to filtrate carry out vacuum distillation until concentration be clear cream after with Silica is uniformly mixed with mass ratio 1:3, and re-dry to moisture content obtains crude product for 5%;
Step 3: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, obtain The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.
<embodiment 3>
Step 1: by 40 parts of Schisandra chinensis, 30 parts of radix pseudostellariae, 30 parts of Semen Nelumbinis, 30 parts of Rhizoma Gastrodiae, 30 parts of Chinese onion White, 20 parts of the dried immature fruit of citron orange, 20 parts of rhizoma atractylodis, 15 parts of citron, 15 parts of myrobalan, 6 parts of betel nut, 6 parts of rhizoma acori graminei, 6 parts of sand Benevolence is ground into the medicinal powder of 100 mesh after being cleaned and dried, medicinal powder and drinking water are stirred into paste, and the condition for being -25 DEG C in temperature Lower freezing is taken out afterwards for 24 hours, obtains the first mixture in 25 DEG C of at a temperature of defrosting;
Step 2: the first mixture is mixed with the ethanol solution that volume fraction is 95% according to mass ratio 1:3, in room temperature Filtered after lower extraction 3h, repeat filter 3 times after merge obtains filtrate, to filtrate carry out vacuum distillation until concentration be clear cream after with Silica is uniformly mixed with mass ratio 1:3, and re-dry to moisture content obtains crude product for 5%;
Step 3: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, obtain The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.
<embodiment 4>
Step 1: by 40 parts of Schisandra chinensis, 30 parts of radix pseudostellariae, 30 parts of Semen Nelumbinis, 30 parts of Rhizoma Gastrodiae, 30 parts of Chinese onion White, 20 parts of the dried immature fruit of citron orange, 20 parts of rhizoma atractylodis, 15 parts of citron, 15 parts of myrobalan, 6 parts of betel nut, 6 parts of rhizoma acori graminei, 6 parts of sand Benevolence is ground into the medicinal powder of 100 mesh after being cleaned and dried, medicinal powder and drinking water are stirred into paste, and the condition for being -25 DEG C in temperature Lower freezing is taken out afterwards for 24 hours, obtains the first mixture in 25 DEG C of at a temperature of defrosting;
Step 2: take the ginseng of 20 parts by weight be sequentially placed into 90 parts, 60 parts, decocted in 30 parts of water, decoction when Length is followed successively by 2.5h, 2h, 1.5h, obtains decoction liquor after 3 parts of liquid remaining after decoction is merged, first carried out to decoction liquor Filter, then ethyl alcohol that 50 parts of volume fractions are 75% is added into decoction liquor and is sufficiently stirred, it filters, is used in combination again after standing for 24 hours The ethyl alcohol that volume fraction is 60% carries out washing until colourless to decoction liquor, stands after 100 parts of water are added, obtains mixed liquor I;
Step 3: by 15 parts of 10 parts of Divine Comedy of cloud Siberian cocklebur, 10 parts of radix polygonati officinalis, 10 parts of radix rehmanniae recen, 1~5 part of the fruit of glossy privet It shreds, and sequentially adds 50 parts thereto, 30 parts of water and successively decocts 2h, 1.5h, 30 parts of volumes point are added after collecting decoction It counts the ethyl alcohol for 75% and is sufficiently stirred to obtain mixed liquor, refrigeration is filtered afterwards for 24 hours, then it is 75% that volume fraction is added thereto Ethyl alcohol is simultaneously sufficiently stirred, and stands after 50 parts of water stirrings are added after standing 20h, obtains mixed liquor I I;
Step 4: the first mixture in mixed liquor I I made from mixed liquor I made from S1, S2, step 2 is mixed, i.e., Obtain the second mixture.
Step 5: be in mass ratio after 1:10 is mixed by the first mixture and the second mixture with volume fraction being 95% Ethanol solution is mixed according to mass ratio 1:3, is filtered after extracting 3h at normal temperature, is repeated merging after filtering 3 times and is obtained filtrate, to filter Liquid carries out vacuum distillation until being concentrated to be uniformly mixed after clear cream with silica with mass ratio 1:3, re-dry to moisture content Crude product is obtained for 5%;
Step 6: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, obtain The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds.
<comparative example 1>
It is not added with the Chinese materia medica preparation of the Chinese materia medica preparation and common prevention and treatment chicken intestinal disease of preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds Basic drawing.
<comparative example 2>
Apramycin is added in Basic drawing
<comparative experiments 1>
On January 23rd, 2018, Rui Dong Farming Ltd., Lingyun county of Guangxi reach the clouds Gallus domesticlus brisson conservation field, choose the icepro for just going out shell Cloud Gallus domesticlus brisson seedling 12000 only carries out brooding the raising in stage, and chicken group is randomly divided into 6 groups, every group 2000, during brooding, implements The whole feeding Basic drawing of example 1~4 and prevention and treatment of the invention reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation mixture, wherein The dosage for preventing and treating the Chinese materia medica preparation for Gallus domesticlus brisson intestines problem of reaching the clouds is 1000mg/kg.Comparative example 1 feeds the base for being not added with any drug Plinth diet, the mixture of comparative example 2 feeding Basic drawing and apramycin, usage amount 1000mg/kg, until after brooding, 6 Group chicken group's broods that the results are shown in Table 1:
Table 1 feeds the Gallus domesticlus brisson seedling that reaches the clouds of different Chinese materia medica preparations
By the experimental result of comparative experiments 1, it is found that prevention and treatment is reached the clouds, the Chinese materia medica preparation of Gallus domesticlus brisson intestines problem can be significantly improved It reaches the clouds the survival rate of Gallus domesticlus brisson seedling, and the disease incidence of the intestines problem for the Gallus domesticlus brisson seedling that reaches the clouds can be effectively reduced, by the system of Examples 1 to 4 It is compared using the Gallus domesticlus brisson seedling that reaches the clouds of the preparation of the intestines problem of common treatment chicken it is found that chicken in meter result and comparative example 2 The disease incidence of weight note and intestines problem after the survival rate of seedling, survival is all significantly improved, therefore the present invention is to reaching the clouds The intestines problem prevention and treatment of Gallus domesticlus brisson has more therapeutic effect, the crow of reaching the clouds in reach the clouds Gallus domesticlus brisson seedling and embodiment 3 in embodiment 4 Baby chick is compared, and the counterpoise after incubation is significantly improved, and in embodiment 4 baby chick feed-weight ratio it is lower than embodiment 3, therefore second The addition of intermediary can be improved the immunity for Gallus domesticlus brisson of reaching the clouds, and enhance the constitution for Gallus domesticlus brisson of reaching the clouds, and increases its weight and reduces material weight Than.
<comparative experiments 2>
On 2 17th, 2018, Rui Dong Farming Ltd., Lingyun county of Guangxi reached the clouds Gallus domesticlus brisson conservation field, chooses 43 ages in days and is in The youth in incubation stage Gallus domesticlus brisson 3000 of reaching the clouds only carries out the raising in incubation stage, and chicken group is randomly divided into 6 groups, every group 500.Implement In example 1~4, the prevention and treatment that whole feeding Basic drawing and content are 1000mg/kg during brooding is reached the clouds in Gallus domesticlus brisson intestines problem The mixture of medicine preparation, comparative example 1 feed Basic drawing, and comparative example 2 feeds Basic drawing and apramycin mixture, and dosage is 1000mg/kg.To incubation, the incubation rearing of 6 groups of chicken groups is as shown in table 2:
Table 2 feeds the Gallus domesticlus brisson seedling that reaches the clouds of different Chinese materia medica preparations
By the experimental result of comparative experiments 2 it is found that with prevention and treatment reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation usage amount Increase, the counterpoise after Gallus domesticlus brisson of reaching the clouds is bred as gradually increases, therefore the Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds can be obvious The youth for improving the incubation stage reaches the clouds the survival rate of Gallus domesticlus brisson, and the morbidity of the intestines problem of young Gallus domesticlus brisson of reaching the clouds can be effectively reduced Rate will use the crow of reaching the clouds of the preparation of the intestines problem of common treatment chicken in the statistical result of Examples 1 to 4 and comparative example 2 The result of baby chick compares, youth reach the clouds the weight note after the survival rate of Gallus domesticlus brisson, survival and intestines problem disease incidence all It is significantly improved, therefore the present invention has a more therapeutic effect to the prevention and treatment of the intestines problem of Gallus domesticlus brisson of reaching the clouds, in embodiment 4 Youth reaches the clouds Gallus domesticlus brisson compared with the youth in embodiment 3 reaches the clouds Gallus domesticlus brisson, and the counterpoise after incubation is still improved, and green in embodiment 4 Reach the clouds in year Gallus domesticlus brisson feed-weight ratio lower than embodiment 3, therefore additions of the second intermediary can be improved the immunity for Gallus domesticlus brisson of reaching the clouds, increasing The constitution of strong Gallus domesticlus brisson of reaching the clouds, increases its weight and reduces feed-weight ratio.
<comparative experiments 3>
On January 19th, 2018, Rui Dong Farming Ltd., Lingyun county of Guangxi reach the clouds Gallus domesticlus brisson conservation field, and selection is reached the clouds Gallus domesticlus brisson 2000 are tested, and chicken group is randomly divided into 5 groups, every group 400.In Examples 1 to 4, whole feeding basis during brooding The prevention and treatment that diet and content are 2000mg/kg reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation mixture, comparative example 1 feeds basis Diet.Experimental period is 5 weeks.The egg laying performance of 5 groups of chicken groups is as shown in table 3:
Table 3 reaches the clouds the laying rate of Gallus domesticlus brisson
It is reached the clouds Gallus domesticlus brisson by the experimental result of comparative experiments 3 it is found that prevention and treatment of the invention is added in the Basic drawing of feeding The laying rate of the Chinese materia medica preparation of intestines problem, the Gallus domesticlus brisson laying hen that can make to reach the clouds increased, and Gallus domesticlus brisson laying hen of reaching the clouds is laid eggs Rate with prevention and treatment reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation usage amount increase correlation.And add in example 4 After entering the second intermediary, the raising of laying rate is more obvious compared to Examples 1 to 3, therefore the present invention can be improved Gallus domesticlus brisson of reaching the clouds Immunity, and improve the laying rate of Gallus domesticlus brisson laying hen of reaching the clouds.
<comparative experiments 4>
On January 19th, 2018, Rui Dong Farming Ltd., Lingyun county of Guangxi reach the clouds Gallus domesticlus brisson conservation field, and selection is reached the clouds Gallus domesticlus brisson 2000 are tested, and chicken group is randomly divided into 5 groups, every group 400.In Examples 1 to 4, whole feeding basis during brooding The prevention and treatment that diet and content are 2000mg/kg reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation mixture, comparative example 1 feeds basis Diet.Count the production filter statistics knot of 5 groups of chicken group poor quality eggs (including check and soft-shelled egg) within 5 weeks experimental periods by a definite date Fruit is as shown in table 4:
Table 4 reaches the clouds the broken shell soft-shelled egg productivity of Gallus domesticlus brisson
It is reached the clouds Gallus domesticlus brisson by the experimental result of comparative experiments 3 it is found that prevention and treatment of the invention is added in the Basic drawing of feeding The Chinese materia medica preparation of intestines problem can reduce the check rate and soft-shelled egg rate of Gallus domesticlus brisson laying hen of reaching the clouds, and Gallus domesticlus brisson laying hen of reaching the clouds Check rate and soft-shelled egg rate with prevention and treatment reach the clouds Gallus domesticlus brisson intestines problem Chinese materia medica preparation usage amount the negatively correlated pass of increase System.And after the second intermediary is added in example 4, check rate and the decline of soft-shelled egg rate are obvious, therefore the present invention can mention The immunity of Gao Lingyun Gallus domesticlus brisson can not only improve the laying rate for Gallus domesticlus brisson of reaching the clouds, and can also improve the egg product for Gallus domesticlus brisson production of reaching the clouds Matter.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited In specific details.

Claims (6)

  1. The Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 1. prevention and treatment is reached the clouds, which is characterized in that the raw material including following parts by weight:
    35~40 parts of Schisandra chinensis, 25~30 parts of radix pseudostellariae, 25~30 parts of Semen Nelumbinis, 25~30 parts of Rhizoma Gastrodiae, 25~30 Longstamen Onion Bulb, 15~20 parts of the dried immature fruit of citron orange, 15~20 parts of rhizoma atractylodis, 7~15 parts of citron, 7~15 parts of myrobalan, 3~6 parts of Bin of part Bulky, 3~6 parts of rhizoma acori graminei, 3~6 parts of fructus amomi.
  2. The Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 2. prevention and treatment as described in claim 1 is reached the clouds, which is characterized in that further include following heavy Measure the raw material of part:
    10~20 parts of ginseng, 10~15 parts of cloud Siberian cocklebur, 5~10 parts of Divine Comedy, 5~10 parts of radix polygonati officinalis, 5~10 parts of Radix Rehmanniae Huang, 1~5 part of the fruit of glossy privet.
  3. The preparation method of the Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 3. prevention and treatment as described in claim 1 is reached the clouds, which is characterized in that packet Include following steps:
    Step 1: by Schisandra chinensis, radix pseudostellariae, Semen Nelumbinis, Rhizoma Gastrodiae, Longstamen Onion Bulb, the dried immature fruit of citron orange, rhizoma atractylodis, citron, myrobalan, betel nut, rhizoma acori graminei, Fructus amomi is ground into the medicinal powder of 100 mesh after being cleaned and dried, medicinal powder is stirred into paste according to said ratio and drinking water, and in temperature It freezes under conditions of being -25 DEG C and takes out afterwards for 24 hours, obtain the first mixture in 25 DEG C of at a temperature of defrosting;
    Step 2: the first mixture is mixed with the ethanol solution that volume fraction is 95% according to mass ratio 1:3, soak at normal temperature Filtered after mentioning 3h, repeat filter 3 times after merge obtains filtrate, to filtrate carry out vacuum distillation until concentration be clear cream after with dioxy SiClx is uniformly mixed with mass ratio 1:3, and re-dry to moisture content obtains crude product for 5%;
    Step 3: being passed through steam sterilizing 25min by crude product sealed packaging, and under conditions of temperature is 105 DEG C, prevented and treated The Chinese materia medica preparation for Gallus domesticlus brisson intestines problem of reaching the clouds.
  4. The preparation method of the Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 4. prevention and treatment as claimed in claim 1 or 2 is reached the clouds, feature exist In, after the first mixture is made by step 1, with volume fraction be 95% ethanol solution mix before, be also added into the second mixing The mass ratio of object, the first mixture and the second mixture is 1:10, and the second mixture is made by following steps:
    S1, take the ginseng of above-mentioned parts by weight be sequentially placed into 90 parts, 60 parts, decocted in 30 parts of water, the duration of decoction is successively For 2.5h, 2h, 1.5h, decoction liquor is obtained after 3 parts of liquid remaining after decoction is merged, first decoction liquor is filtered, then The ethyl alcohol that 50 parts of volume fractions are 75% is added into decoction liquor and is sufficiently stirred, is filtered again after standing for 24 hours, and divided with volume Number carries out washing until colourless to decoction liquor for 60% ethyl alcohol, stands after 100 parts of water are added, obtains mixed liquor I;
    S2, the cloud Siberian cocklebur of above-mentioned parts by weight, Divine Comedy, radix polygonati officinalis, radix rehmanniae recen, the fruit of glossy privet are shredded, and sequentially adds 50 parts, 30 thereto The water of part simultaneously successively decocts 2h, 1.5h, and the ethyl alcohol that 30 parts of volume fractions are 75% is added after collecting decoction and simultaneously is sufficiently stirred to obtain Mixed liquor, refrigeration filter afterwards for 24 hours, then thereto be added volume fraction be 75% ethyl alcohol and be sufficiently stirred, stand 20h after be added It is stood after 50 parts of water stirrings, obtains mixed liquor I I;
    S3, the first mixture in mixed liquor I I made from mixed liquor I made from S1, S2, step 2 is mixed and is mixed to get second Close object.
  5. The preparation method of the Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 5. prevention and treatment as claimed in claim 3 is reached the clouds, which is characterized in that system The ambient temperature range of the standby Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds is 18~30 DEG C, and envionmental humidity range is 30%~70%.
  6. The preparation method of the Chinese materia medica preparation of Gallus domesticlus brisson intestines problem 6. prevention and treatment as claimed in claim 3 is reached the clouds, which is characterized in that In step 2, the pressure condition of vacuum distillation is 4.2kPa.
CN201910209059.4A 2019-03-19 2019-03-19 The Chinese materia medica preparation for preventing and treating Gallus domesticlus brisson intestines problem of reaching the clouds Pending CN109700962A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133131A (en) * 1995-04-10 1996-10-16 李银龙 Chinese medicinal herbs fodder additive and preparation process thereof
CN101543261A (en) * 2009-04-20 2009-09-30 重庆开洲牧业科技开发有限公司 Chinese medicinal herb additive for meat chickens and application
CN104206922A (en) * 2014-09-25 2014-12-17 青岛蓝盈禽业科技有限公司 Feed for chicken breeding and capable of reducing morbidity
CN106110191A (en) * 2016-07-25 2016-11-16 陈建勋 A kind of medicine pill treating gastroenteropathy and complication thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1133131A (en) * 1995-04-10 1996-10-16 李银龙 Chinese medicinal herbs fodder additive and preparation process thereof
CN101543261A (en) * 2009-04-20 2009-09-30 重庆开洲牧业科技开发有限公司 Chinese medicinal herb additive for meat chickens and application
CN104206922A (en) * 2014-09-25 2014-12-17 青岛蓝盈禽业科技有限公司 Feed for chicken breeding and capable of reducing morbidity
CN106110191A (en) * 2016-07-25 2016-11-16 陈建勋 A kind of medicine pill treating gastroenteropathy and complication thereof

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