CN109675171A - Animal stimulating method, device, equipment and storage medium - Google Patents

Animal stimulating method, device, equipment and storage medium Download PDF

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Publication number
CN109675171A
CN109675171A CN201910161056.8A CN201910161056A CN109675171A CN 109675171 A CN109675171 A CN 109675171A CN 201910161056 A CN201910161056 A CN 201910161056A CN 109675171 A CN109675171 A CN 109675171A
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CN
China
Prior art keywords
stimulus
stimulation
animal
random sequence
type
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CN201910161056.8A
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Chinese (zh)
Inventor
张玉楼
刘楠
黄康
蔚鹏飞
王立平
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Priority to CN201910161056.8A priority Critical patent/CN109675171A/en
Publication of CN109675171A publication Critical patent/CN109675171A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K29/00Other apparatus for animal husbandry
    • A01K29/005Monitoring or measuring activity, e.g. detecting heat or mating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0016Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the smell sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0044Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the sight sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0072Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2250/00Specially adapted for animals

Abstract

The embodiment of the invention discloses a kind of animal stimulating method, device, equipment and storage mediums, wherein this method comprises: obtaining the behavioural information and stimulus type of target animal;If determining that behavioural information meets default behavior condition based on stimulus type, it is determined that the corresponding random sequence of stimulus type;Corresponding stimulation is generated according to random sequence, and is applied to target animal.Stimulation in the embodiment of the present invention may be implemented automatic trigger, the expensive equipment such as saves manpower and time, and does not need waveform generator while improving randomness, save the cost of animal stimulation.

Description

Animal stimulating method, device, equipment and storage medium
Technical field
The present embodiments relate to field of computer technology and animal irritant test technical field more particularly to a kind of animals Stimulating method, device, equipment and storage medium.
Background technique
Animal behavior is, the brain regulation animal behavior of animal closely related with animal brain, otherwise the behavior of animal Also reflect the activity situation of brain.Animal behavior research has parsing neural circuitry function and cerebral function region great Meaning, animal behavior research or cerebral disorders therapy target provide Research Thinking, facilitate the disease for treating some brains Disease.It is very helpful that the research of another aspect animal behavior understands animal Social behaviors for the mankind.Study the one of animal behavior Kind necessary means are to give animal various stimulations, and this stimulation, which has plenty of, imitates the stimulation that animal is subject in nature, are had plenty of The stimulation that scientific research personnel gives from research angle.But animal is for regular stimulation extremely well-adapted, this adaptation Property often interference experiment as a result, to animal behavior experiment interfere.Therefore, it is necessary to a kind of systems to give animal random degree Different stimulated, then observation compares the difference of animal behaviors before and after various stimulations, studies animal behavior.
Currently, multi-mode combined stimulation can be implemented by polyesthesia mode programmed electrical stimulation system and to various stimulations Time locking phase is accurately controlled, and can also be controlled laser via by visualization light stimulus system and be generated different light stimulus. But stimulation mode in the prior art needs to manually adjust using expensive devices such as waveform generators, increases cost, expends Biggish manpower and time, and the stimulation given has very much regularity, and the strong adaptability of animal will affect animal behavior Research.
Summary of the invention
The embodiment of the invention provides a kind of animal stimulating method, device, equipment and storage mediums, can solve existing skill At high cost and stimulation has very much the technical problem of regularity in art.
In a first aspect, the embodiment of the invention provides a kind of animal stimulating methods, comprising:
Obtain the behavioural information and stimulus type of target animal;
If determining that the behavioural information meets default behavior condition based on the stimulus type, it is determined that the stimulus type Corresponding random sequence;
Corresponding stimulation is generated according to the random sequence, and is applied to the target animal.
Second aspect, the embodiment of the invention also provides a kind of animal stimulating apparatus, which includes:
Data obtaining module, for obtaining the behavioural information and stimulus type of target animal;
Random sequence module, if for determining that the behavioural information meets default behavior condition based on the stimulus type, Then determine the corresponding random sequence of the stimulus type;
Stimulating module for generating corresponding stimulation according to the random sequence, and is applied to the target animal.
Further, the stimulus type include light stimulus, visual stimulus, olfactory stimulation, sonic stimulation, electric current stimulation and At least one of in beard stimulation.
Further, the random sequence module includes behavior conditioning unit, described when the stimulus type is light stimulus Behavioural information includes speed and position,
The behavior conditioning unit is specifically used for:
Determine that the speed of the target animal meets the position of pre-set velocity threshold value and the target animal in preset areas Within the scope of domain, it is determined that the behavioural information meets default behavior condition.
Further, the random sequence module further includes random sequence determination unit, the random sequence determination unit Include:
Stimulus variable subelement, for determining corresponding stimulus variable, the stimulus variable packet according to the stimulus type Include frequency, intensity, size and in the time at least one of;
Stimulus variable template subelement, for determining goal stimulus variable template, the target based on the stimulus variable The quantity of stimulus variable template is at least two;
Random sequence generates subelement, for being generated by random function based on the random of the goal stimulus variable template Sequence.
Further, the stimulating module is specifically used for:
The set of the corresponding goal stimulus variable template of the random sequence is inputted into the corresponding stimulation of the stimulus type In generator, corresponding stimulation is generated.
Further, which further includes stimulus variable template-setup module, the stimulus variable template-setup module tool Body is used for:
Before determining goal stimulus variable template based on the stimulus variable, the stimulus variable template of preset quantity is set, It include the preset value of at least one stimulus variable in the stimulus variable template.
The third aspect, the embodiment of the invention also provides a kind of equipment, the equipment includes:
One or more processors;
Storage device, for storing one or more programs;
When one or more of programs are executed by one or more of processors, so that one or more of processing Device realizes animal stimulating method as described above.
Fourth aspect, the embodiment of the invention also provides a kind of computer readable storage mediums, are stored thereon with computer Program, the program realize animal stimulating method as described above when being executed by processor.
The embodiment of the present invention passes through the behavioural information and stimulus type for obtaining target animal, if determining row based on stimulus type Meet default behavior condition for information, it is determined that the corresponding random sequence of stimulus type, and it is corresponding according to random sequence generation Stimulation, is applied to the target animal.The stimulus type generation pair that the embodiment of the present invention directly can need to apply according to animal The random sequence answered, and corresponding stimulation is generated based on the random sequence and is applied on animal, the stimulation in the embodiment of the present invention Automatic trigger may be implemented, save manpower and time while improving randomness, and do not need the valuableness such as waveform generator Equipment, save animal stimulation cost.
Detailed description of the invention
Fig. 1 is the flow chart of the animal stimulating method in the embodiment of the present invention one;
Fig. 2 is the schematic diagram of the animal stimulating method in the embodiment of the present invention one;
Fig. 3 is the flow chart of the animal stimulating method in the embodiment of the present invention two;
Fig. 4 is the structural schematic diagram of the animal stimulating apparatus in the embodiment of the present invention three;
Fig. 5 is the structural schematic diagram of the equipment in the embodiment of the present invention four.
Specific embodiment
The present invention is described in further detail with reference to the accompanying drawings and examples.It is understood that this place is retouched The specific embodiment stated is used only for explaining the present invention rather than limiting the invention.It also should be noted that in order to just Only the parts related to the present invention are shown in description, attached drawing rather than entire infrastructure.
Embodiment one
Fig. 1 is the flow chart of the animal stimulating method in the embodiment of the present invention one, and the present embodiment is applicable to realize animal The case where stimulation, this method can be executed by animal stimulating apparatus, which can be realized by the way of software and hardware, should Device is configured in equipment, such as the equipment can be computer etc..
Animal stimulating method in the embodiment of the present invention can be based on the computer realization configured with animal stimulating apparatus, specifically Referring to fig. 2, Fig. 2 is the schematic diagram of the animal stimulating method in the embodiment of the present invention one.Behavior analyzer in figure is available To the behavioural information of animal, and when the behavior, information met some requirements, sends stimulation instructions and pierced to the animal in computer Excitation device, animal stimulating apparatus can call pre-set stochastic ordering sequence generator according to experiment need to generate it is corresponding with Machine sequence, and the random sequence is sent to stimulation generator by serial ports, to generate corresponding stimulation, and it is dynamic to act on target On object.Target animal in figure is small white mouse, and animal stimulating apparatus can be only fitted in a control platform of computer, the control Platform can be built using the Measurement index of open source, and the graphic user interface of various stimulations can be set (Graphical User Interface, GUI), can be can be convenient visually to adjust according to the requirement of experimenter stimulated Various variables in journey.
As shown in Figure 1, this method can specifically include:
S110, the behavioural information and stimulus type for obtaining target animal.
Wherein, target animal can be that arbitrarily can satisfy the animal of experiment demand, to target animal in the present embodiment Volume is not construed as limiting, and the animal and larger animal of small volume can be with, such as small white mouse, dog, transgene pig or monkey etc..Row It is to measure the parameter of target animal behavior for information, may include the parameters such as speed, acceleration, head deflection angles and positions. Stimulus type is the specific stimulation determined according to experiment demand, is not made in the present embodiment to the quantity of stimulus type and specific type It limits, such as stimulus type may include light stimulus, visual stimulus, olfactory stimulation, sonic stimulation, electric current stimulation and beard stimulation Deng at least one in stimulation.
In the present embodiment, the behavioural information for obtaining target animal can be realized by two ways, and mode one can be with are as follows: logical At least one data for obtaining the preset collected target animal of at least one sensor are crossed, mathematical analysis is carried out to the data Available behavioural information;Mode two can be with are as follows: by preset processing routine or Processing Algorithm to image capture device (example Such as camera) acquisition target animal picture or video carry out image procossing, the behavioural information of available target animal. Treatment process using aforesaid way two is more simple and effective.Further, according to user to the key of preset stimulus type Selection, the stimulus type of available target animal, wherein the key of stimulus type can pass through hardware or software realization.
Illustratively, if camera collects the video of target animal in a period of time, analysis video can track target The moving distance of target animal, and then the movement speed of available target animal is calculated in the motion profile of animal.
If S120, determining that behavioural information meets default behavior condition based on stimulus type, it is determined that stimulus type is corresponding Random sequence.
Wherein, presetting behavior condition can be set according to stimulus type and actual conditions.Random sequence (random Sequence), also referred to as random number series, full name sequence of random variables, the ordered series of numbers being made of stochastic variable.
Optionally, when stimulus type is light stimulus, behavioural information may include speed and position, and it is true to be based on stimulus type Determine behavioural information and meet default behavior condition, comprising: determines that the speed of target animal meets pre-set velocity threshold value and target is dynamic The position of object is within the scope of predeterminable area, it is determined that behavioural information meets default behavior condition.Wherein pre-set velocity threshold value can be with It including pre-set velocity maximum value and pre-set velocity minimum value, is not construed as limiting in shape the present embodiment of predeterminable area, such as default Region can be round or rectangular etc..If the speed of target animal is less than or equal to pre-set velocity maximum value and is more than or equal to pre- If speed minimum value, and the position for determining target animal can then determine the row of the target animal within the scope of predeterminable area Meet default behavior condition for information.In addition, can also include determining stimulation time, if really when stimulus type is light stimulus Current time is determined not at stimulation time interval, then can determine that target animal can apply stimulation in current time.
Specifically, being determined if determining that behavioural information meets default behavior condition based on stimulus type according to stimulus type Corresponding stimulus variable, and generate by random function the random sequence of the stimulus variable.Wherein stimulus variable is to influence stimulation The parameter of the corresponding stimulation of type, stimulus variable may include at least one in frequency, intensity, size and time etc..This reality If applying the corresponding stimulus variable of a stimulus type in example, since the different corresponding stimulus variables of stimulus type is different, base The preset value of multiple stimulus variables can be preset in each stimulus variable.According to stimulus type determine stimulus variable it Afterwards, it can choose the preset value of the wherein at least two stimulus variable, and generated by random function and be based at least two thorns The random sequence of the preset value of violent change amount.For example, determining stimulus variable is frequency, selection if stimulus type is light stimulus Predetermined frequency value is 5Hz, 10Hz, 15Hz and 20Hz, and predetermined frequency value is indicated by 1-4 respectively, then the random sequence generated Can be " 4231 ".
S130, corresponding stimulation is generated according to random sequence, and is applied to target animal.
Specifically, stimulation generator can be by pre- by the corresponding stimulation generator of random sequence input stimulus type If algorithm or program parse the random sequence, generate corresponding stimulation, and be applied to target animal.Stimulate the tool of generator Body type is corresponding with stimulus type, if such as stimulus type be light stimulus when, stimulation generator can be to be built-in with arduino The laser of development board or 51 single-chip microcontrollers.
Illustratively, if stimulus type be light stimulus, by random sequence by serial ports be sent to arduino development board or 51 single-chip microcontroller of person, arduino development board or 51 single-chip microcontrollers can call pre-set waveform to generate program decoding stochastic ordering Corresponding waveform is arranged and generated, laser is sent to, laser is made to issue the corresponding specific frequency of random sequence and certain pulses The laser of width, and it is applied to by optical fiber the intracerebral of target animal.It is not construed as limiting in color the present embodiment of laser, such as can Think blue or yellow.
Corresponding stimulation is generated according to random sequence, and is applied to after target animal, target animal stimulation can be compared The variations such as Behavioral change, brain wave variation and the pupil variation of front and back, study animal behavior, parse neural circuitry and cerebral function Region, while help is provided for treatment disease.
The present embodiment is by obtaining the behavioural information and stimulus type of target animal, if determining that behavior is believed based on stimulus type Breath meets default behavior condition, it is determined that the corresponding random sequence of stimulus type, and corresponding stimulation is generated according to random sequence, It is applied to target animal.The present embodiment directly can generate corresponding random sequence according to the stimulus type that animal needs to apply, And corresponding stimulation is generated based on the random sequence and is applied on animal, automatic trigger may be implemented in the stimulation in the present embodiment, Manpower and time are saved, and does not need waveform generator etc. expensive equipment while improving randomness, saves animal The cost of stimulation.
Embodiment two
Fig. 3 is the flow chart of the animal stimulating method in the embodiment of the present invention two.Base of the present embodiment in above-described embodiment On plinth, further materialization has been carried out to above-mentioned animal stimulating method.Correspondingly, as shown in figure 3, the method for the present embodiment has Body includes:
S210, the behavioural information and stimulus type for obtaining target animal.
Wherein, behavioural information is to measure the parameter of target animal behavior, may include speed, acceleration, head deflection angle The parameters such as degree and position.Stimulus type is the specific stimulation determined according to experiment demand, to the number of stimulus type in the present embodiment Amount and specific type are not construed as limiting, such as stimulus type may include light stimulus, visual stimulus, olfactory stimulation, sonic stimulation, electricity At least one of in the stimulation such as stream stimulation and beard stimulation.
If the quantity of stimulus type is only one, current stimulation is known as single stimulation, if the quantity of stimulus type is Two or more when, current stimulation is known as collective stimulus property.The a variety of different random stimulations of animal are given for research The neural circuitry mechanism of brain, cerebral function region, the Social behaviors etc. for understanding animal are very important.Such as light stimulus can Specific neuron is activated or inhibited with point-device, and then influences the information transmitting of neural circuitry, it is random by giving animal Varying strength or frequency light stimulus, can accurately find influence animal behavior light intensity or frequency, analysis stimulation front and back The Behavioral change of animal is conducive to study brain sensory perception function.
S220, determine whether behavioural information meets default behavior condition based on stimulus type.
Wherein, presetting behavior condition can be set according to stimulus type and actual conditions.
Illustratively, when stimulus type is light stimulus, behavioural information may include speed and position, be based on stimulus type Determine that behavioural information meets default behavior condition, comprising: determine that the speed of target animal meets pre-set velocity threshold value and target The position of animal is within the scope of predeterminable area, it is determined that behavioural information meets default behavior condition.
Determine whether behavioural information meets default behavior condition based on stimulus type, if behavioural information meets default behavior item Part then executes S230, if behavioural information is unsatisfactory for default behavior condition, returns and executes S210, continues to obtain target animal Behavioural information and stimulus type.
S230, corresponding stimulus variable is determined according to stimulus type.
Stimulus variable is the parameter for influencing the corresponding stimulation of stimulus type, and stimulus variable may include frequency, intensity, size With in time etc. at least one of.And stimulus variable can also be configured according to the actual situation, be not limited to above-mentioned frequency Rate, intensity, size and time etc..
Specifically, the contingency table of stimulus type and stimulus variable can be preset in animal stimulating apparatus, according to stimulation The contingency table of type and the stimulus type and stimulus variable can determine and the associated stimulus variable of the stimulus type.Such as work as thorn When sharp type is light stimulus, associated stimulus variable can be laser frequency, pulse width and stimulation time;When stimulus type is When visual stimulus, associated stimulus variable can be the size, shape and topology knot of black disk in approaching experiment (looming experiment) Structure.
S240, goal stimulus variable template is determined based on stimulus variable.
Optionally, before determining goal stimulus variable template based on stimulus variable, further includes: the stimulation of preset quantity is set Variable template includes the preset value of at least one stimulus variable in stimulus variable template.Wherein preset quantity can be according to reality Situation is configured, and type, quantity and the preset value of stimulus variable template moderate stimulation variable can also carry out according to the actual situation Setting, such as a stimulus variable template moderate stimulation variable are laser frequency, pulse width and the stimulation time currently stimulated, are swashed The preset value of light frequency is 5Hz (hertz), and the preset value of pulse width is 3ms (millisecond), and the preset value of stimulation time is 4s (second), the stimulus variable template can be expressed as " send_command=' F0005D003T0004 ' ".
The quantity of goal stimulus variable template is at least two.Specifically, can be according to experiment demand based on stimulus variable It selects at least two stimulus variable templates as goal stimulus variable template, such as can choose one of stimulus variable rule Property variation and the fixed multiple stimulus variable templates of other stimulus variables as goal stimulus variable template.
S250, the random sequence based on goal stimulus variable template is generated by random function.
In the present embodiment, digital representation goal stimulus variable template, the corresponding goal stimulus of a number can be passed through Variable template generates the sequence of the random digit in the digital scope by random function.Illustratively, if goal stimulus variable The quantity of template is 5, indicates above-mentioned 5 goal stimulus variable template by digital 1-5 respectively, is generated by random function Random sequence can be " 34251 ".Wherein the length of random sequence can be configured according to experiment demand.
S260, the corresponding stimulation of the set input stimulus type of the corresponding goal stimulus variable template of random sequence is generated In device, corresponding stimulation is generated, and be applied to target animal.
Wherein, stimulate the concrete type of generator corresponding with stimulus type, if such as stimulus type be light stimulus when, thorn Sharp generator can be the laser for being built-in with arduino development board or 51 single-chip microcontrollers;If stimulus type is visual stimulus, depending on Feel stimulation type can there are many, such as the black disk of different size of black disk, black disk of different shapes and topological structure Visual patterns are waited, the equipment in generator including built-in Matlab software and the refresh rate set according to experiment demand is stimulated, divides The different displays of resolution and size;If stimulus type is olfactory stimulation, stimulation generator can contain air inlet by one The composition such as container, stepper motor, slide unit and air pump controls air pump by stepper motor and slide unit, by the gas for controlling air inlet Type and volume realize the olfactory stimulation for applying varying strength and type to animal.The corresponding stimulation life of different stimulus types It grows up to be a useful person herein without enumerating.
It, can according to random sequence due to the corresponding goal stimulus variable template of each of random sequence random digit To obtain the set of one group of goal stimulus variable template, corresponding stimulation will be generated in the set input stimulus generator.
It should be noted that the animal stimulating method in the present embodiment is also provided with retransmission mechanism, when the row of target animal When meeting default behavior condition for information, behavior analyzer sends control platform of the stimulation instructions to computer, the control of computer Platform processed sends random sequence and stimulation instructions and gives stimulation generator, if being not detected what stimulation generator returned in preset time Order is received, then retransmits the stimulation instructions and gives stimulation generator, until receiving instruction until detecting.Wherein behavioural analysis The control platform in computer can be set in device, can also individually be configured.It, can be further by the setting of retransmission mechanism Guarantee the transmission success rate of stimulation instructions, and then guarantees the generation of stimulation.
The applicable animal species of animal stimulating method in the present embodiment are more, are applicable not only to a variety of rodents, also suitable With other species, and it is suitable for various types of places such as kinds of experiments place, such as square, labyrinth and elevated plus.
The present embodiment determines behavioural information based on stimulus type by the behavioural information and stimulus type of acquisition target animal Whether satisfaction presets behavior condition, if so, determining the corresponding stimulus variable of stimulus type, determines that target is pierced based on stimulus variable Violent change amount template, and the random sequence based on goal stimulus variable template is generated by random function, random sequence is corresponding In the corresponding stimulation generator of set input stimulus type of goal stimulus variable template, corresponding stimulation is generated, and be applied to Target animal.The present embodiment directly can generate corresponding random sequence according to the stimulus type that animal needs to apply, and be based on The random sequence generates corresponding stimulation and is applied on animal, and the stimulation in the present embodiment may be implemented automatic trigger, improve with The expensive equipment such as manpower and time are saved while machine, and does not need waveform generator, save animal stimulation Cost, the type and locating environment to animal are without limitation;And stimulation instructions are further ensured that by increasing retransmission mechanism Success rate is sent, and then guarantees the generation of stimulation.
Embodiment three
Fig. 4 is the structural schematic diagram of the animal stimulating apparatus in the embodiment of the present invention three, and the present embodiment is applicable to realize The case where animal stimulates.Animal stimulating apparatus provided by the embodiment of the present invention can be performed provided by any embodiment of the invention Animal stimulating method has the corresponding functional module of execution method and beneficial effect.The device specifically includes data obtaining module 310, random sequence module 320 and stimulating module 330, in which:
Data obtaining module 310, for obtaining the behavioural information and stimulus type of target animal;
Random sequence module 320, if for determining that behavioural information meets default behavior condition based on stimulus type, it is determined that The corresponding random sequence of stimulus type;
Stimulating module 330 for generating corresponding stimulation according to random sequence, and is applied to target animal.
The embodiment of the present invention passes through the behavioural information and stimulus type for obtaining target animal, if determining row based on stimulus type Meet default behavior condition for information, it is determined that the corresponding random sequence of stimulus type, and it is corresponding according to random sequence generation Stimulation, is applied to the target animal.The stimulus type generation pair that the embodiment of the present invention directly can need to apply according to animal The random sequence answered, and corresponding stimulation is generated based on the random sequence and is applied on animal, the stimulation in the embodiment of the present invention Automatic trigger may be implemented, save manpower and time while improving randomness, and do not need the valuableness such as waveform generator Equipment, save animal stimulation cost.
Further, stimulus type includes light stimulus, visual stimulus, olfactory stimulation, sonic stimulation, electric current stimulation and beard At least one of in stimulation.
Further, random sequence module 320 includes behavior conditioning unit, when stimulus type is light stimulus, behavioural information Including speed and position,
Behavior conditioning unit is specifically used for:
Determine that the speed of target animal meets the position of pre-set velocity threshold value and target animal within the scope of predeterminable area, Then determine that behavioural information meets default behavior condition.
Further, random sequence module 320 further includes random sequence determination unit, and random sequence determination unit includes:
Stimulus variable subelement, for determining corresponding stimulus variable according to stimulus type, stimulus variable includes frequency, strong Degree, size and in the time at least one of;
Stimulus variable template subelement, for determining goal stimulus variable template, goal stimulus variable based on stimulus variable The quantity of template is at least two;
Random sequence generates subelement, for generating the stochastic ordering based on goal stimulus variable template by random function Column.
Further, stimulating module 330 is specifically used for:
By in the corresponding stimulation generator of set input stimulus type of the corresponding goal stimulus variable template of random sequence, Generate corresponding stimulation.
Further, which further includes stimulus variable template-setup module, and stimulus variable template-setup module is specifically used In:
Before determining goal stimulus variable template based on stimulus variable, the stimulus variable template of preset quantity is set, is stimulated It include the preset value of at least one stimulus variable in variable template.
Animal thorn provided by any embodiment of the invention can be performed in animal stimulating apparatus provided by the embodiment of the present invention The method of swashing, has the corresponding functional module of execution method and beneficial effect.
Example IV
Fig. 5 is the structural schematic diagram of the equipment in the embodiment of the present invention four.Fig. 5, which is shown, to be suitable for being used to realizing that the present invention is real Apply the block diagram of the example devices 412 of mode.The equipment 412 that Fig. 5 is shown is only an example, should not be to the embodiment of the present invention Function and use scope bring any restrictions.
As shown in figure 5, equipment 412 is showed in the form of common apparatus.The component of equipment 412 can include but is not limited to: One or more processor 416, storage device 428 connect different system components (including storage device 428 and processor 416) bus 418.
Bus 418 indicates one of a few class bus structures or a variety of, including storage device bus or storage device control Device processed, peripheral bus, graphics acceleration port, processor or total using the local of any bus structures in a variety of bus structures Line.For example, these architectures include but is not limited to industry standard architecture (Industry Subversive Alliance, ISA) bus, microchannel architecture (Micro Channel Architecture, MAC) bus is enhanced Isa bus, Video Electronics Standards Association (Video Electronics Standards Association, VESA) local are total Line and peripheral component interconnection (Peripheral Component Interconnect, PCI) bus.
Equipment 412 typically comprises a variety of computer system readable media.These media can be it is any can be by equipment The usable medium of 412 access, including volatile and non-volatile media, moveable and immovable medium.
Storage device 428 may include the computer system readable media of form of volatile memory, such as arbitrary access Memory (Random Access Memory, RAM) 430 and/or cache memory 432.Equipment 412 can be wrapped further Include other removable/nonremovable, volatile/non-volatile computer system storage mediums.Only as an example, storage system 434 can be used for reading and writing immovable, non-volatile magnetic media (Fig. 5 do not show, commonly referred to as " hard disk drive ").Although It is not shown in Fig. 5, the disc driver for reading and writing to removable non-volatile magnetic disk (such as " floppy disk ") can be provided, and To removable anonvolatile optical disk, such as CD-ROM (Compact Disc Read-Only Memory, CD-ROM), number Optic disk (Digital Video Disc-Read Only Memory, DVD-ROM) or other optical mediums) read-write CD drive Dynamic device.In these cases, each driver can be connected by one or more data media interfaces with bus 418.It deposits Storage device 428 may include at least one program product, which has one group of (for example, at least one) program module, this A little program modules are configured to perform the function of various embodiments of the present invention.
Program/utility 440 with one group of (at least one) program module 442 can store in such as storage dress It sets in 428, such program module 442 includes but is not limited to operating system, one or more application program, other program moulds It may include the realization of network environment in block and program data, each of these examples or certain combination.Program module 442 usually execute function and/or method in embodiment described in the invention.
Equipment 412 (such as keyboard, can also be directed toward terminal, display 424 and thorn with one or more external equipments 414 Swash generator etc.) communication, the terminal interacted with the equipment 412 can be also enabled a user to one or more to be communicated, and/or with Any terminal (such as network interface card, the modem that the equipment 412 is communicated with one or more of the other computing terminal Etc.) communication.This communication can be carried out by input/output (I/O) interface 422.Also, equipment 412 can also pass through net Network adapter 420 and one or more network (such as local area network (Local Area Network, LAN), wide area network (Wide Area Network, WAN) and/or public network, such as internet) communication.As shown in figure 5, network adapter 420 passes through always Line 418 is communicated with other modules of equipment 412.It should be understood that although not shown in the drawings, can be used with bonding apparatus 412 other Hardware and/or software module, including but not limited to: microcode, terminal driver, redundant processor, external disk drive array, Disk array (Redundant Arrays of Independent Disks, RAID) system, tape drive and data are standby Part storage system etc..
The program that processor 416 is stored in storage device 428 by operation, thereby executing various function application and number According to processing, such as realize animal stimulating method provided by the embodiment of the present invention, this method comprises:
Obtain the behavioural information and stimulus type of target animal;
If determining that behavioural information meets default behavior condition based on stimulus type, it is determined that the corresponding stochastic ordering of stimulus type Column;
Corresponding stimulation is generated according to random sequence, and is applied to target animal.
Embodiment five
The embodiment of the present invention five additionally provides a kind of computer readable storage medium, is stored thereon with computer program, should The animal stimulating method as provided by the embodiment of the present invention is realized when program is executed by processor, this method comprises:
Obtain the behavioural information and stimulus type of target animal;
If determining that behavioural information meets default behavior condition based on stimulus type, it is determined that the corresponding stochastic ordering of stimulus type Column;
Corresponding stimulation is generated according to random sequence, and is applied to target animal.
The computer storage medium of the embodiment of the present invention, can be using any of one or more computer-readable media Combination.Computer-readable medium can be computer-readable signal media or computer readable storage medium.It is computer-readable Storage medium for example may be-but not limited to-the system of electricity, magnetic, optical, electromagnetic, infrared ray or semiconductor, device or Device, or any above combination.The more specific example (non exhaustive list) of computer readable storage medium includes: tool There are electrical connection, the portable computer diskette, hard disk, random access memory (RAM), read-only memory of one or more conducting wires (ROM), erasable programmable read only memory (EPROM or flash memory), optical fiber, portable compact disc read-only memory (CD- ROM), light storage device, magnetic memory device or above-mentioned any appropriate combination.In this document, computer-readable storage Medium can be any tangible medium for including or store program, which can be commanded execution system, device or device Using or it is in connection.
Computer-readable signal media may include in a base band or as carrier wave a part propagate data-signal, Wherein carry computer-readable program code.The data-signal of this propagation can take various forms, including but unlimited In electromagnetic signal, optical signal or above-mentioned any appropriate combination.Computer-readable signal media can also be that computer can Any computer-readable medium other than storage medium is read, which can send, propagates or transmit and be used for By the use of instruction execution system, device or device or program in connection.
The program code for including on computer-readable medium can transmit with any suitable medium, including --- but it is unlimited In wireless, electric wire, optical cable, RF etc. or above-mentioned any appropriate combination.
The computer for executing operation of the present invention can be write with one or more programming languages or combinations thereof Program code, described program design language include object oriented program language-such as Java, Smalltalk, C++, It further include conventional procedural programming language-such as " C " language or similar programming language.Program code can be with It fully executes, partly execute on the user computer on the user computer, being executed as an independent software package, portion Divide and partially executes or executed on remote computer or terminal completely on the remote computer on the user computer.It is relating to And in the situation of remote computer, remote computer can pass through the network of any kind --- including local area network (LAN) or extensively Domain net (WAN)-be connected to subscriber computer, or, it may be connected to outer computer (such as provided using Internet service Quotient is connected by internet).
Note that the above is only a better embodiment of the present invention and the applied technical principle.It will be appreciated by those skilled in the art that The invention is not limited to the specific embodiments described herein, be able to carry out for a person skilled in the art it is various it is apparent variation, It readjusts and substitutes without departing from protection scope of the present invention.Therefore, although being carried out by above embodiments to the present invention It is described in further detail, but the present invention is not limited to the above embodiments only, without departing from the inventive concept, also It may include more other equivalent embodiments, and the scope of the invention is determined by the scope of the appended claims.

Claims (10)

1. a kind of animal stimulating method characterized by comprising
Obtain the behavioural information and stimulus type of target animal;
If determining that the behavioural information meets default behavior condition based on the stimulus type, it is determined that the stimulus type is corresponding Random sequence;
Corresponding stimulation is generated according to the random sequence, and is applied to the target animal.
2. the method according to claim 1, wherein the stimulus type includes light stimulus, visual stimulus, smell At least one of in stimulation, sonic stimulation, electric current stimulation and beard stimulation.
3. according to the method described in claim 2, it is characterized in that, the stimulus type be light stimulus when, the behavioural information Including speed and position,
Determine that the behavioural information meets default behavior condition based on the stimulus type, comprising:
Determine that the speed of the target animal meets the position of pre-set velocity threshold value and the target animal in predeterminable area model In enclosing, it is determined that the behavioural information meets default behavior condition.
4. the method according to claim 1, wherein determining the corresponding random sequence of the stimulus type, comprising:
Corresponding stimulus variable is determined according to the stimulus type, and the stimulus variable includes frequency, intensity, size and in the time At least one of;
Determine that goal stimulus variable template, the quantity of the goal stimulus variable template are at least two based on the stimulus variable It is a;
The random sequence based on the goal stimulus variable template is generated by random function.
5. according to the method described in claim 4, it is characterized in that, generating corresponding stimulation according to the random sequence, comprising:
The set of the corresponding goal stimulus variable template of the random sequence is inputted the corresponding stimulation of the stimulus type to generate In device, corresponding stimulation is generated.
6. according to the method described in claim 4, it is characterized in that, determining goal stimulus variable template based on the stimulus variable Before, further includes:
The stimulus variable template of preset quantity is set, includes the default of at least one stimulus variable in the stimulus variable template Value.
7. a kind of animal stimulating apparatus characterized by comprising
Data obtaining module, for obtaining the behavioural information and stimulus type of target animal;
Random sequence module, if for determining that the behavioural information meets default behavior condition based on the stimulus type, really Determine the corresponding random sequence of the stimulus type;
Stimulating module for generating corresponding stimulation according to the random sequence, and is applied to the target animal.
8. device according to claim 7, which is characterized in that the stimulus type includes light stimulus, visual stimulus, smell At least one of in stimulation, sonic stimulation, electric current stimulation and beard stimulation.
9. a kind of equipment, which is characterized in that the equipment includes:
One or more processors;
Storage device, for storing one or more programs;
When one or more of programs are executed by one or more of processors, so that one or more of processors are real Now such as animal stimulating method as claimed in any one of claims 1 to 6.
10. a kind of computer readable storage medium, is stored thereon with computer program, which is characterized in that the program is by processor Such as animal stimulating method as claimed in any one of claims 1 to 6 is realized when execution.
CN201910161056.8A 2019-03-04 2019-03-04 Animal stimulating method, device, equipment and storage medium Pending CN109675171A (en)

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Application publication date: 20190426