CN109663098A - A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method - Google Patents

A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method Download PDF

Info

Publication number
CN109663098A
CN109663098A CN201910031431.7A CN201910031431A CN109663098A CN 109663098 A CN109663098 A CN 109663098A CN 201910031431 A CN201910031431 A CN 201910031431A CN 109663098 A CN109663098 A CN 109663098A
Authority
CN
China
Prior art keywords
chinese medicine
patch
dysmenorrhea
palace
warms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910031431.7A
Other languages
Chinese (zh)
Inventor
李江滨
何冬梅
蔡格琦
李雪雪
陈美迎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Medical University
Original Assignee
Guangdong Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Medical University filed Critical Guangdong Medical University
Priority to CN201910031431.7A priority Critical patent/CN109663098A/en
Publication of CN109663098A publication Critical patent/CN109663098A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235Foeniculum (fennel)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to Traditional Chinese medicinal patch technical fields, and in particular to a kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method.The Chinese medicine warms up palace dysmenorrhea navel patch, using trigone, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Fructus Liquidambaris, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii as raw material, with production is simple, cost is relatively low, analgesic effect clear advantage, the Chinese medicine warms up palace dysmenorrhea navel patch can be in conjunction with the warm palace effect of physical chemistry heat dissipation and two kinds of effects of Chinese materia medica preparation percutaneous dosing, it is a kind of novel herbal mixture for showing consideration for, and being easy for carrying and using.The Chinese medicine warms up the preparation method of palace dysmenorrhea navel patch, has the advantages that with production is simple, cost is relatively low.The Chinese medicine warm up palace dysmenorrhea navel patch application method, have the characteristics that it is easy to use, a drug can make drug for a long time with constant speed per hour enter in vivo, play long-acting, slow releasing function, both stable blood concentration had been maintained, has avoided peak valley phenomenon, and reduce administration number of times.

Description

A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method
Technical field
The present invention relates to Traditional Chinese medicinal patch technical fields, and in particular to a kind of Chinese medicine warms up palace dysmenorrhea navel patch and preparation method thereof And methods for using them.
Background technique
Dysmenorrhea refers to before and after menstrual period or occurs during passing through that lower abdomen spasmic pain, pain in the loins, lower abdomen pendant rise or companion simultaneously There are pale complexion, dripping cold sweat, cold limbs or nausea and vomiting etc., is more common in teenager, unmarried and married for production person, is most often One of gynecological disease seen, and with menstrual cycle recurrent exerbation, seriously affect the life and work of women.Clinic is often by it at present It is divided into primary and two kinds secondary.Primary dysmenorrhea refer to more reproductive organs without obvious lesion person, therefore also known as functional dysmenorrhea, often Puberty women is seen, caused by acquired dysmenorrhea mostly has organic disease because of reproductive organs, such as mullerianosis, ovarian bursa Swollen, pelvic infection or fibroid (especially mucosa hysteromyoma) or placement intrauterine device etc..
Domestic data shows that dysmenorrhoea illness rate is 22.5%~46.1%, foreign countries' report teenager's Primary Dysmenorrhea in Adolescent Girls hair Sick rate is 20%~90%, wherein having 15% to suffer from severe dysmenorrhea.Chinese medicine thinks that dysmenorrhea is " the not general rule as caused by many reasons Bitterly ".Doctor trained in Western medicine then thinks mainly to increase with prostaglandin level related.Western medical treatment there is no satisfactory method, general at present Alleviate symptom using the method for taking anodyne or anti-inflammatory drug, but the chief culprit of pain is caused not to be removed, and traditional Chinese medicine is controlled Treating dysmenorrhea has good effect, the advantages of few side effects, the Chinese medicine treatment maximum advantage of dysmenorrhea be can diagnosis and treatment based on an overall analysis of the illness and the patient's condition, not only treated the symptoms but also It effects a permanent cure.This can be divided into two steps, first is that removal leads to the root of disease, as effect a permanent cure;Second is that according to personal constitution, in menstrual period Analgesic, as treats the symptoms.
Modern medicine study shows that umbilical region barrier action is poor, Qi Xia fat-free mass, contains blood vessel abundant, permeability By force, it absorbs fastly, is conducive to drug and penetrates absorption.By umbilical region administration, it is avoided that gastrointestinal environment to the interference of drug effect and liver " first pass effect " can make drug dispersion penetrate into blood circulation particularly with the addition of the effective component of the warming channel and expelling cold dredging collateral of energy, The whole province's effect is generated to reach therapeutic purposes.Since its is easy to use, a drug can make drug for a long time with constant speed per hour Into internal, long-acting, slow releasing function is played, stable blood concentration has both been maintained, avoids peak valley phenomenon, and reduces administration time Number.Thus, the dysmenorrhoea Chinese traditional medicine navel patch with warm palace effect is that have very big researching value and meaning.Currently, although domestic have Sale of the part through pain patch, but the function of all only radiating, play the role of dysmenorrhoea palliative.
Summary of the invention
It, should it is an object of the present invention in view of the deficiencies of the prior art, providing a kind of warm palace dysmenorrhea navel patch of Chinese medicine Chinese medicine, which warms up palace dysmenorrhea navel patch, not only has the function of heat dissipation, but also can play the role for the treatment of the symptoms and effecting a permanent cure to dysmenorrhoea.
The second object of the present invention is to provide a kind of system of warm palace dysmenorrhea navel patch of Chinese medicine in view of the deficiencies of the prior art Preparation Method.
One of to achieve the goals above, the present invention adopts the following technical scheme:
A kind of warm palace dysmenorrhea navel patch of Chinese medicine is provided, including Chinese medicine patch and for attaching the warm of the Chinese medicine patch Palace patch, the lotion of the Chinese medicine patch includes the Chinese medicinal component of following parts by weight:
The Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into the cream Body.
Preferably, a kind of Chinese medicine warms up palace dysmenorrhea navel patch, and the lotion of the Chinese medicine patch includes following parts by weight Several Chinese medicinal components:
More preferably, a kind of Chinese medicine warms up palace dysmenorrhea navel patch, it is characterised in that: the lotion of the Chinese medicine patch Chinese medicinal component including following parts by weight:
The weight ratio of the camellia oil and the Chinese medicinal component is 1.5~2.5:1.
The weight ratio of the pharmagel and the primary medicine oil is 1.5~2.5:1.
To achieve the goals above two, the present invention adopts the following technical scheme:
The preparation method that a kind of Chinese medicine warms up palace dysmenorrhea navel patch is provided, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, and then mixing is placed in pulverizer In, it pulverizes and sieves, obtains Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first soaked Bubble, then decoction to oil of opening fire boil, and then reduce firepower, decoct to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain primary Medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to certain temperature, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
In above-mentioned technical proposal, one the step of the first step in, be then carried out dehydrating, make aqueous in each raw material Amount is no more than 5%.
In above-mentioned technical proposal, two the step of the first step in, first carry out immersion 22h~26h.
In above-mentioned technical proposal, three the step of the first step in, when primary medicine oil temperature is down to 190 DEG C~210 DEG C, Pharmagel is added.
To achieve the goals above three, the present invention adopts the following technical scheme:
A kind of application method of warm palace dysmenorrhea navel patch of Chinese medicine is provided, the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Compared with prior art, beneficial effect is the present invention:
(1) a kind of Chinese medicine provided by the invention warms up palace dysmenorrhea navel patch, with production is simple, cost is relatively low, analgesic effect Clear advantage, which warms up palace dysmenorrhea navel patch can be in conjunction with the warm palace effect of physical chemistry heat dissipation and Chinese materia medica preparation percutaneous dosing two Kind effect is a kind of novel herbal mixture for showing consideration for, and being easy for carrying and using.
(2) a kind of Chinese medicine provided by the invention warms up palace dysmenorrhea navel patch, and raw material is all selected from natural Chinese medicinal herb, chooses three Rib, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Fructus Liquidambaris, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii these types have breaking blood and promoting the circulation of qi, dissipate The medicinal material of cold analgesic effect, the primary treatment qi and blood cold of insufficiency type, the waist abdomen severe pain when moon caused by palace cold stagnates is premenstrual and passes through are free of There is any hormone, it is without any side effects to skin also without any stimulation, after each bulk pharmaceutical chemicals mixing, there is synergistic effect, In dysmenorrhea treatment, remarkable result is achieved.
(3) a kind of Chinese medicine provided by the invention warms up palace dysmenorrhea navel patch, is affixed below underbelly navel in the form of application, The shortcomings that having evaded Chinese medicine bitter will not cause any irritation to injure to oral cavity, stomach and intestine, and be difficult to clean there is no plaster The drawbacks of, Qi Xia fat-free mass contains blood vessel abundant, and permeability is strong, absorbs fastly, is conducive to drug and penetrates absorption, not only may be used To alleviate menstrual period pain, and the menstrual period abnormal symptom of incongruity amount of bleeding can be effectively administered, the cold body symptom ice-cold to trick Also there is good relaxation effect.
(4) a kind of Chinese medicine provided by the invention warms up the preparation method of palace dysmenorrhea navel patch, makes simple, cost with having Lower advantage, and its emplastrum periphery is that there is heat production to warm up Gong Gongneng for iron powder, water, active carbon, vermiculite etc., its temperature can be stablized Be maintained between 40 DEG C~65 DEG C, can 10 hours of persistent fever, medicament duration can be heated, endlessly hot-fluid has Conducive to drug diffusion absorption, enhances pharmacological property, serve and relieve pain, is warming channel and expelling cold.
(5) a kind of Chinese medicine provided by the invention warm up palace dysmenorrhea navel patch application method, have the characteristics that it is easy to use, one Secondary medication can be such that drug enters in vivo with constant speed per hour for a long time, play long-acting, slow releasing function, it is dense both to have maintained stable blood medicine Degree, avoids peak valley phenomenon, and reduce administration number of times.
Specific embodiment
In order to which the technical problems, technical solutions and beneficial effects solved by the present invention is more clearly understood, below in conjunction with Embodiment, the present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only used to explain The present invention is not intended to limit the present invention.
Embodiment 1.
A kind of warm palace dysmenorrhea navel patch of Chinese medicine, a kind of warm palace dysmenorrhea navel patch of Chinese medicine, it is characterised in that: including traditional Chinese medicinal ointment Patch and the Warn uterus paste for attaching Chinese medicine patch, the lotion of Chinese medicine patch include the Chinese medicinal component of following parts by weight:
Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into lotion.
In the present embodiment, the weight ratio of camellia oil and Chinese medicinal component is 2:1.
In the present embodiment, the weight ratio of pharmagel and primary medicine oil is 2:1.
A kind of above-mentioned Chinese medicine warm up palace dysmenorrhea navel patch preparation method, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, make the water content in each raw material No more than 5%, then mixing is placed in pulverizer, is pulverized and sieved, is obtained Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated For 24 hours, then decoction to oil of opening fire boils, and then reduces firepower, decocts to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain just Grade medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to 200 DEG C, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
A kind of above-mentioned Chinese medicine warms up the application method of palace dysmenorrhea navel patch, and the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Embodiment 2.
A kind of warm palace dysmenorrhea navel patch of Chinese medicine, a kind of warm palace dysmenorrhea navel patch of Chinese medicine, it is characterised in that: including traditional Chinese medicinal ointment Patch and the Warn uterus paste for attaching Chinese medicine patch, the lotion of Chinese medicine patch include the Chinese medicinal component of following parts by weight:
Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into lotion.
In the present embodiment, the weight ratio of camellia oil and Chinese medicinal component is 1.5:1.
In the present embodiment, the weight ratio of pharmagel and primary medicine oil is 1.5:1.
A kind of above-mentioned Chinese medicine warm up palace dysmenorrhea navel patch preparation method, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, make the water content in each raw material No more than 5%, then mixing is placed in pulverizer, is pulverized and sieved, is obtained Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated 22h, then decoction to oil of opening fire boil, and then reduce firepower, decoct to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain just Grade medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to 190 DEG C, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
A kind of above-mentioned Chinese medicine warms up the application method of palace dysmenorrhea navel patch, and the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Embodiment 3.
A kind of warm palace dysmenorrhea navel patch of Chinese medicine, a kind of warm palace dysmenorrhea navel patch of Chinese medicine, it is characterised in that: including traditional Chinese medicinal ointment Patch and the Warn uterus paste for attaching Chinese medicine patch, the lotion of Chinese medicine patch include the Chinese medicinal component of following parts by weight:
Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into lotion.
In the present embodiment, the weight ratio of camellia oil and Chinese medicinal component is 2.5:1.
In the present embodiment, the weight ratio of pharmagel and primary medicine oil is 2.5:1.
A kind of above-mentioned Chinese medicine warm up palace dysmenorrhea navel patch preparation method, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, make the water content in each raw material No more than 5%, then mixing is placed in pulverizer, is pulverized and sieved, is obtained Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated 26h, then decoction to oil of opening fire boil, and then reduce firepower, decoct to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain just Grade medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to 210 DEG C, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
A kind of above-mentioned Chinese medicine warms up the application method of palace dysmenorrhea navel patch, and the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Embodiment 4.
A kind of warm palace dysmenorrhea navel patch of Chinese medicine, a kind of warm palace dysmenorrhea navel patch of Chinese medicine, it is characterised in that: including traditional Chinese medicinal ointment Patch and the Warn uterus paste for attaching Chinese medicine patch, the lotion of Chinese medicine patch include the Chinese medicinal component of following parts by weight:
Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into lotion.
In the present embodiment, the weight ratio of camellia oil and Chinese medicinal component is 1.8:1.
In the present embodiment, the weight ratio of pharmagel and primary medicine oil is 1.8:1.
A kind of above-mentioned Chinese medicine warm up palace dysmenorrhea navel patch preparation method, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, make the water content in each raw material No more than 5%, then mixing is placed in pulverizer, is pulverized and sieved, is obtained Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated 23h, then decoction to oil of opening fire boil, and then reduce firepower, decoct to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain just Grade medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to 195 DEG C, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
A kind of above-mentioned Chinese medicine warms up the application method of palace dysmenorrhea navel patch, and the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Embodiment 5.
A kind of warm palace dysmenorrhea navel patch of Chinese medicine, a kind of warm palace dysmenorrhea navel patch of Chinese medicine, it is characterised in that: including traditional Chinese medicinal ointment Patch and the Warn uterus paste for attaching Chinese medicine patch, the lotion of Chinese medicine patch include the Chinese medicinal component of following parts by weight:
Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into lotion.
In the present embodiment, the weight ratio of camellia oil and Chinese medicinal component is 2.2:1.
In the present embodiment, the weight ratio of pharmagel and primary medicine oil is 2.2:1.
A kind of above-mentioned Chinese medicine warm up palace dysmenorrhea navel patch preparation method, it the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Lu Lu Logical, semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, make the water content in each raw material No more than 5%, then mixing is placed in pulverizer, is pulverized and sieved, is obtained Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated 25h, then decoction to oil of opening fire boil, and then reduce firepower, decoct to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain just Grade medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary When medicine oil temperature is down to 205 DEG C, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies nonwoven on lotion The Chinese medicine patch is made in cloth;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, leech Stone, sodium chloride, SAP water-absorbing resin and water after mixing evenly, are fitted into non-woven bag, and surrounding compacting sealing is complete, then in nonwoven Thermally conductive constant-temperature cloth is sticked in cloth bag side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or The method of suture is combined with each other, vacuum packaging, obtains the Chinese medicine and warms up palace dysmenorrhea navel patch.
A kind of above-mentioned Chinese medicine warms up the application method of palace dysmenorrhea navel patch, and the Chinese medicine patch is attached in the Warn uterus paste Between position, then Warn uterus paste face human body " very acupuncture point " is pasted on skin again.
Experiment:
1, object and method
1.1 case selections and grouping
Choose 150 patients, wherein lower abdomen severe pain patient 50, inferior belly gas pain 60, waist abdominal pain patient 40, the age It is 16-45 years old, most of unmarried, it is primary dysmenorrhea, the course of disease -5 years 6 months.
1.2 diagnostic criteria diagnostic criteria are made a definite diagnosis referring to the diagnostic criteria in " Gynecology of Chinese Medicine ".Dysmenorrhea is women's positive value warp Occur periodical underbelly pain before and after phase or menstrual period or even severe pain causes faintness person, and with other not just as mammary swellings, hand Foot is ice-cold etc., so that influencing work and life.For married woman through gynecologial examination, unmarried female excludes life through B-mode ultrasonography Grow organ organic disease.
Above-mentioned dysmenorrhea Warn uterus paste is taken out inner bag without rubbing by 1.3 treatment methods, throws off adhesive surface, Chinese medicine pack is pasted Warn uterus paste face human body " very acupuncture point " (lower three cun of navel) is pasted on skin to Warn uterus paste middle position.Menstruation first three days are opened Begin patch, a daily patch, until ischomenia is no longer used, still such as aforesaid operations, 1 month as a treatment course within secondary month.
Criterion of therapeutical effect: recovery from illness: clinical symptoms disappear, and functional activity is normal, and next menstruation is without hypogastralgia;It improves: clinical Symptom part hour is clearly better;Invalid: clinical symptoms, sign are unchanged.
2, treatment results
Through counting, the results are shown in Table 1:
Table 1:
As can be known from Table 1, the treatment total effective rate for calculating patch is 94%, and the present invention is to caused by menstrual cycle of female Underbelly pain, trick is ice-cold significant curative effect, can be used for a long time, without any side effects.
The therapeutic effect of dysmenorrhea plaster of the present invention can also be illustrated by following instance:
Case one: Korea Spro, 22 years old, student, menstrual period waist abdominal pain, with cold limbs, dripping cold sweat, dizziness and nausea vomiting, warp It is dim that phase lacks color.Application dysmenorrhea plaster of the invention is treated, and after treating 1 course for the treatment of, symptom mitigates, and 3 courses for the treatment of of application, symptom disappears It loses.Recurrence that so far there are no.
Case two: Chen, female is 23 years old, unmarried, menstrual period lower abdomen severe pain, pale complexion, expression pain, cold limbs, nausea Vomiting, mild diarrhea, Hypomenorrhea, color purple is dim block, seriously affects work, through a variety of treatments, effect is bad.This hair of application afterwards Bright dysmenorrhea plaster is treated, and after treating 3 courses for the treatment of, symptom is substantially reduced, is continued to paste 1 course for the treatment of, is almost recovered.It is multiple that so far there are no Hair.
Case three: river, female is 37 years old, married, and menstrual period inferior belly gas pain is in great pain, and sitting is unbearable, pale complexion, four limbs Ice-cold, anodyne is often taken in nausea and vomiting.Application dysmenorrhea plaster of the invention is treated, and after treating 3 courses for the treatment of, symptom is obvious Mitigate, continues to paste 2 courses for the treatment of, be almost recovered.Recurrence that so far there are no.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than the present invention is protected The limitation of range is protected, although explaining in detail referring to preferred embodiment to the present invention, those skilled in the art are answered Work as understanding, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the reality of technical solution of the present invention Matter and range.

Claims (10)

1. a kind of Chinese medicine warms up palace dysmenorrhea navel patch, it is characterised in that: including Chinese medicine patch and for attaching the Chinese medicine patch Warn uterus paste, the lotion of the Chinese medicine patch includes the Chinese medicinal component of following parts by weight:
The Chinese medicinal component obtains primary medicine oil after camellia oil shifts to an earlier date, and pharmagel is then added and is mixed and made into the lotion.
2. a kind of Chinese medicine according to claim 1 warms up palace dysmenorrhea navel patch, it is characterised in that: the lotion of the Chinese medicine patch Chinese medicinal component including following parts by weight:
3. a kind of Chinese medicine according to claim 1 warms up palace dysmenorrhea navel patch, it is characterised in that: the lotion of the Chinese medicine patch Chinese medicinal component including following parts by weight:
4. a kind of Chinese medicine according to claim 1 warms up palace dysmenorrhea navel patch, it is characterised in that: the camellia oil and it is described in The weight ratio of medicine component is 1.5~2.5:1.
5. a kind of Chinese medicine according to claim 1 warms up palace dysmenorrhea navel patch, it is characterised in that: the pharmagel with it is described The weight ratio of primary medicine oil is 1.5~2.5:1.
6. a kind of preparation method of the warm palace dysmenorrhea navel patch of Chinese medicine described in claim 1 to 5 any one, it is characterised in that: It the following steps are included:
The first step, the preparation of Chinese medicine patch:
Step 1 prepares Chinese medicine mixing fine powders: by the raw material trigone of formula ratio, curcuma zedoary, turmeric, fennel seeds, the root of three-nerved spicebush, Fructus Liquidambaris, Semen litchi, psoralea corylifolia, green peel and Fructus Aurantii are respectively washed, dry, and are then carried out dehydrating, and then mixing is placed in pulverizer, It pulverizes and sieves, obtains Chinese medicine mixing fine powders;
Step 2 prepares primary medicine oil: Chinese medicine mixing fine powders made from step 1 being placed in camellia oil, are first impregnated, then Decoction to oil of opening fire boils, and then reduces firepower, decocts to Chinese medicine mixing fine powders in coke yellow, filtering and removing slag obtain primary medicine oil;
Step 3 prepares lotion: cooling of ceasing fire after decocting primary medicine oil made from step 2 to no steam of opening fire, to primary medicine oil When temperature is down to certain temperature, pharmagel is added, stirs evenly, obtains lotion;
Step 4 prepares Chinese medicine patch: lotion made from step 3 being coated in release paper and applies non-woven fabrics on lotion, is made At the Chinese medicine patch;
The preparation of Warn uterus paste: second step makes non-woven bag using non-woven fabrics, by secondary reduction iron, activated carbon powder, vermiculite, chlorine Change sodium, SAP water-absorbing resin and water after mixing evenly, be fitted into non-woven bag, surrounding compacting sealing is complete, then in non-woven bag one Thermally conductive constant-temperature cloth is sticked in side, and the Warn uterus paste is made;
Third step, finished product preparation: by Warn uterus paste made from Chinese medicine patch made from the first step and second step using bonding or suture Method be combined with each other, be vacuum-packed, obtain the Chinese medicine warm up palace dysmenorrhea navel patch.
7. the preparation method that a kind of Chinese medicine according to claim 6 warms up palace dysmenorrhea navel patch, it is characterised in that: described first It in the step of step one, is then carried out dehydrating, the water content in each raw material is made to be no more than 5%.
8. the preparation method that a kind of Chinese medicine according to claim 6 warms up palace dysmenorrhea navel patch, it is characterised in that: described first In the step of step two, immersion 22h~26h is first carried out.
9. the preparation method that a kind of Chinese medicine according to claim 6 warms up palace dysmenorrhea navel patch, it is characterised in that: described first In the step of step three, when primary medicine oil temperature is down to 190 DEG C~210 DEG C, pharmagel is added.
10. a kind of application method of the warm palace dysmenorrhea navel patch of Chinese medicine described in claim 1 to 5 any one, it is characterised in that: The Chinese medicine patch is attached to the middle position of the Warn uterus paste, is then again pasted on Warn uterus paste face human body " very acupuncture point " On skin.
CN201910031431.7A 2019-01-14 2019-01-14 A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method Pending CN109663098A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910031431.7A CN109663098A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910031431.7A CN109663098A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method

Publications (1)

Publication Number Publication Date
CN109663098A true CN109663098A (en) 2019-04-23

Family

ID=66150557

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910031431.7A Pending CN109663098A (en) 2019-01-14 2019-01-14 A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method

Country Status (1)

Country Link
CN (1) CN109663098A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110613782A (en) * 2019-08-15 2019-12-27 郑州巨人生化集团有限公司 External paste for warming uterus and relieving pain and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108096329A (en) * 2018-03-08 2018-06-01 刘晓闯 It is a kind of to be used to treat Chinese medicine composition, dysmenorrhea plaster of dysmenorrhoea and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108096329A (en) * 2018-03-08 2018-06-01 刘晓闯 It is a kind of to be used to treat Chinese medicine composition, dysmenorrhea plaster of dysmenorrhoea and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110613782A (en) * 2019-08-15 2019-12-27 郑州巨人生化集团有限公司 External paste for warming uterus and relieving pain and preparation method thereof

Similar Documents

Publication Publication Date Title
CN109663098A (en) A kind of Chinese medicine warms up palace dysmenorrhea navel patch and its preparation method and application method
CN103212020B (en) Traditional Chinese medicine composition for treating functional dyspepsia
CN103301365A (en) Cataplasm for treating cervical spondylosis and preparation method thereof
CN100571747C (en) A kind of Chinese medicine decoction for the treatment of dysmenorrhea
CN104857463A (en) Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis
CN104771469A (en) External traditional Chinese medicine for treating ankle soft tissue injury
CN101181456B (en) Plaster for curing bone fracture assimilation and preparation method thereof
CN104383220A (en) Formulation and method for treating kidney deficiency
CN100536907C (en) Osteopathy treating Chinese medicine
CN102772532B (en) Infantile diarrhea treatment traditional Chinese medicine powder of palm patch for external use
CN101797291A (en) Traditional Chinese medicine for treating osteoproliferation
CN100589819C (en) Chinese medicine for oral administration for treating lumbar hyperosteogeny
CN101062137B (en) Chinese medicine for curing female emmeniopathy
CN105944074A (en) Rheumatoid joint plaster and preparation method thereof
CN104784619A (en) Traditional Chinese medicine for treating post-traumatic early limb swelling
CN103961611A (en) Traditional Chinese medicine pills for treating liver tumors
CN101028405B (en) Chinese-medicinal decoction for treating difficult menstruation
CN116492393A (en) Traditional Chinese medicine formula for treating varicose veins
CN110960609A (en) Motherwort herb and wormwood herb powder
CN110292614A (en) A kind of Chinese medicine composition for treating the protrasion of the lumbar intervertebral disci
CN111494479A (en) Traditional Chinese medicine gout soaking agent and preparation method thereof
CN109288941A (en) A kind of plaster and its preparation process
CN110090288A (en) The preparation method of positive moxibustion patch is helped in a kind of external application
CN106620381A (en) Medicine for treating thighbone necrosis
CN105770834A (en) Traditional Chinese medicine pills for treating polymyalgia rheumatica

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190423