CN109662995A - A kind of traditional Chinese medicine plaster and preparation method thereof for treating the protrasion of the lumbar intervertebral disci - Google Patents

A kind of traditional Chinese medicine plaster and preparation method thereof for treating the protrasion of the lumbar intervertebral disci Download PDF

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CN109662995A
CN109662995A CN201811310566.9A CN201811310566A CN109662995A CN 109662995 A CN109662995 A CN 109662995A CN 201811310566 A CN201811310566 A CN 201811310566A CN 109662995 A CN109662995 A CN 109662995A
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protrasion
lumbar intervertebral
chinese
treating
asarum
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柴仪
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    • AHUMAN NECESSITIES
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Abstract

Protrasion of the lumbar intervertebral disci Chinese medicine external plaster and preparation method thereof is treated the present invention relates to a kind of, it is made of following raw material: Chinese ephedra 40-50g, asarum 20-30g, lepidium seed 20-30g, semen brassicae 60-80g, rhizoma corydalis 70-80g, Radix Glycyrrhizae 70-80g, Radix Astragali 140-150g, above all medicines are matched by constant weight number.The present invention prepares simple and convenient, and quickly, significant effect, side effect is low, highly-safe for effect, easy to use clean, has apparent alleviate and therapeutic effect for the acute and chronic protrasion of the lumbar intervertebral disci.

Description

A kind of traditional Chinese medicine plaster and preparation method thereof for treating the protrasion of the lumbar intervertebral disci
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of traditional Chinese medicine plaster for treating the protrasion of the lumbar intervertebral disci and its preparation side Method.
Background technique
The protrasion of the lumbar intervertebral disci is common one of the illness of orthopaedics.It is primarily due to lumber ertebral disc each section (nucleus pulposus, fiber Ring and cartilage plate), especially nucleus pulposus, after having different degrees of degenerative change, under the action of external force factor, the fibre of interverbebral disc Ring breakage is tieed up, nucleus pulposus causes adjacent spinal nerve root to be pierced from prominent (or abjection) Yu Houfang of rupture place or intraspinal tube Swash or oppresses, so that flank pain is generated, a series of clinical symptoms such as side lower limb or double lower limb numbness, pain.Now due to The change of quality of life, working time extend, and working condition is mostly handled official business with sitting posture, the disease more rejuvenation.Treatment waist now The main gimmick of the protrusion of the intervertebral disc with non-operative treatment (strict bed rest, traction, massage therapy, cortin epidural injection, The supportive treatments such as nucleus pulposus chemical dissolution method, glucosaminicacid calcium and chondroitin sulfate), percutaneous section and suction of nucleus art/nucleus pulposus laser Gasify art, operative treatment.Traditional Chinese medicine plaster is the important measures of external treatment of traditional Chinese medicine, is imitated especially in conjunction with the electric heating of modern treatment instrument It answers, increases the penetrating power of Chinese medicine.Have the characteristics that effect is directly goed deep into, is significant in efficacy, the treatment protrasion of the lumbar intervertebral disci has Good curative effect is based on this, and the Chinese medicine external plaster for being directed to the treatment protrasion of the lumbar intervertebral disci is widely studied and pays close attention to, such as CN201010544408.7 discloses a kind of externally applied ointment and preparation method thereof of activating microcirculation and removing stasis medicinal.The active constituent of the Chinese medicine is by working as Return, safflower, Rhizoma Chuanxiong, teasel root, the rhizome of davallia, herba taxilli, the root of Dahurain angelica, Rhizoma Et Radix Notopterygii, ramulus cinnamomi, pawpaw, radix achyranthis bidentatae, dragon's blood, frankincense, myrrh, Moschus and MEIHUA BINGPIAN are by constant weight number proportion composition.CN03809751.6 discloses a kind of the outer of the protrasion of the lumbar intervertebral disci With plaster and preparation method thereof.The traditional Chinese medicine plaster is by 50 ~ 100g of Cortex Eucommiae, 50 ~ 100g of the rhizome of davallia, 50 ~ 100g of radix dipsaci, rhizoma cibotii 50 ~ 100g, 50 ~ 100g of monkshood, 50 ~ 100g of Semen Strychni, 50 ~ 100g of semen momordicae, 50 ~ 100g of Chinese ephedra, 50 ~ 100g of lopseed, 50 ~ 100g of rhizoma arisaematis, 50 ~ 100g of Rhizoma Gastrodiae, 10 ~ 50g of scorpio, 10 ~ 50g of centipede, 50 ~ 100g of pheretima, 50 ~ 100g of the root of three-nerved spicebush, 50 ~ 100g of fennel seeds, 50 ~ 100g of corydalis tuber, 50 ~ 100g of Eupolyphoge sinensis, 50 ~ 100g of leech, 50 ~ 100g of grub, 10 ~ 30g of borneol, 50 ~ 100g of rheum officinale, 50 ~ 100g of kaladana, 50 ~ 100g of native copper, 50 ~ 100g of Radix Angelicae Sinensis, 50 ~ 100g of baiyao, keel 50 ~ 100g, 50 ~ 100g of cortex albiziae, 50 ~ 100g of olibanum, myrrh 50- 100g, 50 ~ 100g of catechu, 10 ~ 50g of dragon's blood, pearl powder 10 ~ 50g, beeswax 200g.The above Chinese materia medica preparation is different for the protrasion of the lumbar intervertebral disci rules for the treatment of.In order to prevent lumber ertebral disc prominent The purpose of the development of disease and elimination pain out, improves the quality of life and health quality of modern, needs to invent treatment Effect is more preferable, safer quick traditional Chinese medicine plaster preparation.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicine external plaster for treating the protrasion of the lumbar intervertebral disci, have clinic and control Therapeutic effect is good, highly-safe, the quick obvious feature of effect, and provides preparation method simultaneously.
To solve the above problems, the technical solution used in the present invention is:
Protrasion of the lumbar intervertebral disci Chinese medicine external plaster and preparation method thereof is treated the present invention relates to a kind of, it is former by following parts by weight Material is made: Chinese ephedra 40-50g, asarum 20-30g, lepidium seed 20-30g, semen brassicae 60-80g, rhizoma corydalis 70-80g, Radix Glycyrrhizae 70- 80g, Radix Astragali 140-150g,.
In some embodiments, be made of the following raw material: Chinese ephedra 40g, asarum 30g, lepidium seed 30g, semen brassicae 80g, Rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
In some embodiments, be made of the following raw material: Chinese ephedra 50g, asarum 20g, lepidium seed 20g, semen brassicae 60g, Rhizoma corydalis 70g, Radix Glycyrrhizae 70g, Radix Astragali 140g.
In some embodiments, be made of the following raw material: Chinese ephedra 50g, asarum 30g, lepidium seed 30g, semen brassicae 75g, Rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
In some embodiments, be made of the following raw material: Chinese ephedra 50g, asarum 20g, lepidium seed 30g, semen brassicae 60g, Rhizoma corydalis 70g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
Another aspect of the present invention provides a kind of preparation method of above-mentioned traditional Chinese medicine plaster, which is characterized in that weighs above-mentioned each Raw material is ground into powdery, and the above powder of Chinese herbs is added in 60 ~ 80 DEG C of pockmarks oil vessels of preheating, is heated to 250 ~ 350 DEG C, stirring Lead powder is added, 60 ~ 80 DEG C are cooled to after herb powder is merged with lead powder, stops stirring when paste is presented in container, it will Paste is contained to cover into the small container got ready in advance, deposits in and is protected from light, is spare at dry and ventilated, makes it with micro-wave oven when use It is heated to 60 ~ 80 DEG C to take in right amount, then wraps up in and affected part is spread on cloth or gauze.
The beneficial effects of adopting the technical scheme are that
Epheday intermedia of the present invention: inducing sweat and dispelling exogenous evils are freeinged lung and relieving asthma, inducing diuresis for removing edema.Return lung, bladder meridian;It is modern often based on this product, with card Compatibility can treat migraine geroderma itch, pernio, allergic rhinitis, sleep apnea syndrome and Dou Xingxin Move too slow, hiccup, upper gastrointestinal bleeding, renal failure, lumbar sprain, sciatica, Raynaud's disease, infectious purulent inflammation, chronic Pharyngitis, toothache etc..Asarum: acrid in flavour and warm in nature.Return heart, lung, kidney channel.Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, warming lung and resolving fluid.For chill Flu is had a headache, toothache, nasal congestion, allergic rhinitis, nasosinusitis, rheumatic arthralgia, sputum cough.Lepidium seed: enter lung, bladder, large intestine channel. Purging the lung of pathogenic fire sending down abnormally ascending, eliminating phlegm and relieving asthma, inducing diuresis for removing edema expel the heat-evil by heresy.The dyspnea and cough with excessive sputum of sputum stop up lung, pulmonary abscess, oedema, chest and abdomen ponding are small Just unfavorable, the asthma of chronic cor pulmonale, heart failure is swollen.Also ulcer malignant sore, scrofula tuberculosis are controlled.Semen brassicae: odorless, taste It is pungent, peppery.Enter lung meridian.Warm lung slit phlegm benefit gas, dissipating bind are removed obstruction in channels to relieve pain.It reduces phlegm and avoid drink;Mass dissipating and swelling eliminating.Main cough and phlegm;Chest Full hypochondriac pain;Extremity numbness;Painful swelling of joints;Multiple abscess with damp phlegm;Negative subcutaneous ulcer pyogenic infections.Control acute mastitis, breast cancer, mammary gland pain, tuberculosis, phlegm retention cough Asthma, fullness in chest and hypochondrium pain, gastric disorder causing nausea vomiting, aphasia from apoplexy, limbs numbness pain is numb, tinea pedis, negative subcutaneous ulcer, pyogenic infections, treating swelling and pain by traumatic injury.Prolong recklessly Rope: pungent;It is bitter;Temperature;It is nontoxic.Liver;Stomach;The heart;Lung;The spleen channel.Promoting blood circulation;Dissipate the stasis of blood;Qi-regulating;Analgesic.The main all pains of trusted subordinate's waist and knee;Menstruation is not It adjusts;Abdominal mass;Metrorrhagia;Postpartum anemic fainting;Lochiorrhagia;Traumatic injury.Radix Glycyrrhizae: it is sweet in flavor, it is mild-natured.Return heart, lung, spleen, stomach meridian.Tonifying spleen benefit Gas, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, phlegm of coughing More, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.Radix Astragali: it is warm-natured, it is sweet in flavor.Return lung, spleen, liver, kidney Through.Invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub-official prolapses, chronic The long disunion of nephritic proteinuria, diabetes, the open sore part.
The application epheday intermedia return lung, bladder meridian have the effect of inducing diuresis for removing edema, cure mainly acute lumbar muscle sprain, sciatica is Monarch drug in a prescription is helped with asarum, lepidium seed, semen brassicae, corydalis tuber for treating acute stage pain, swelling, ministerial drug based on large dose Astragalis, because All medicines all enter lung channel, so that the gas of the whole body is entered kidney channel with all medicine effect of enhancing of Radix Astragali palpus, Radix Glycyrrhizae coordinating the drug actions of a prescription, lower lung in communication Kidney, the plaster inducing diuresis for removing edema so that Chai Shi waist is dashed forward, removes obstruction in channels to relieve pain, and promoting the circulation of qi dissolving stasis is big method, and function and effect are quickly obvious, side effect Low, preparation is simple, deposits with convenient.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, invention is carried out combined with specific embodiments below Clear, complete description.
Lead powder in the present embodiment is lead orthoplumbate of the purity 95% or more.
Embodiment 1
A kind of Chinese medicine external plaster for treating the protrasion of the lumbar intervertebral disci, is made of the following raw material: Chinese ephedra 40g, asarum 30g, Roripa Li 30g, semen brassicae 80g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
Specifically the preparation method is as follows: weighing above-mentioned 7 taste Chinese medicine material according to the above weight, it is ground into powdery, in above Medicine end is added in 70 ± 2 DEG C of flaxseed oil 1000g containers of preheating, is heated to 300 ± 2 DEG C, lead powder 300g is added in stirring, to traditional Chinese medicine powder End is cooled to 70 ± 2 DEG C after merge with lead powder, and when paste is presented in container, stopping is stirred, and paste is contained into getting ready in advance Small container in cover, deposit in and be protected from light, be spare at dry and ventilated.
Application method: so that it is heated to 60 ~ 80 DEG C with micro-wave oven when use and take in right amount, then wrap up in cloth or gauze hot compress Affected part, 8-14 hours each, 1-2 times daily, every patch is 1 course for the treatment of with 1 day, 14 days.
Embodiment 2
A kind of Chinese medicine external plaster for treating the protrasion of the lumbar intervertebral disci, is made of the following raw material: Chinese ephedra 50g, asarum 20g, Roripa Li 20g, semen brassicae 60g, rhizoma corydalis 70g, Radix Glycyrrhizae 70g, Radix Astragali 140g.
Specifically the preparation method is as follows: weighing above-mentioned 7 taste Chinese medicine material according to the above weight, it is ground into powdery, in above Medicine end is added in 80 ± 2 DEG C of flaxseed oil 1000g containers of preheating, is heated to 350 ± 2 DEG C, lead powder 300g is added in stirring, to traditional Chinese medicine powder End is cooled to 80 ± 2 DEG C after merge with lead powder, and when paste is presented in container, stopping is stirred, and paste is contained into getting ready in advance Small container in cover, deposit in and be protected from light, be spare at dry and ventilated.
Application method: so that it is heated to 60 ~ 80 DEG C with micro-wave oven when use and take in right amount, then wrap up in cloth or gauze hot compress Affected part, 8-14 hours each, 1-2 times daily, every patch is 1 course for the treatment of with 1 day, 14 days.
Embodiment 3:
A kind of Chinese medicine external plaster for treating the protrasion of the lumbar intervertebral disci, is made of the following raw material: Chinese ephedra 50g, asarum 30g, Roripa Li 30g, semen brassicae 75g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
Preparation method: above-mentioned 7 taste Chinese medicine material is weighed according to the above weight, powdery is ground into, the above powder of Chinese herbs is added It preheats in 60 ± 2 DEG C of flaxseed oil 1000g containers, is heated to 250 ± 2 DEG C, lead powder 300g is added in stirring, to herb powder and lead powder It is cooled to 60 ± 2 DEG C after fusion, stops stirring when paste is presented in container, paste is contained into the small container got ready in advance Interior capping is deposited in and is protected from light, is spare at dry and ventilated.
Application method: so that it is heated to 60 ~ 80 DEG C with micro-wave oven when use and take in right amount, then wrap up in cloth or gauze hot compress Affected part, 8-14 hours each, 1-2 times daily, every patch is 1 course for the treatment of with 1 day, 14 days.
Embodiment 4:
A kind of Chinese medicine external plaster for treating the protrasion of the lumbar intervertebral disci, is made of the following raw material: Chinese ephedra 50g, asarum 20g, Roripa Li 30g, semen brassicae 60g, rhizoma corydalis 70g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
Specifically the preparation method is as follows: weighing above-mentioned 7 taste Chinese medicine material according to the above weight, it is ground into powdery, in above Medicine end is added in 70 ± 2 DEG C of flaxseed oil 1000g containers of preheating, is heated to 300 ± 2 DEG C, lead powder 300g is added in stirring, to traditional Chinese medicine powder End is cooled to 70 ± 2 DEG C after merge with lead powder, and when paste is presented in container, stopping is stirred, and paste is contained into getting ready in advance Small container in cover, deposit in and be protected from light, be spare at dry and ventilated.
Application method: so that it is heated to 60 ~ 80 DEG C with micro-wave oven when use and take in right amount, then wrap up in cloth or gauze hot compress Affected part, 8-14 hours each, 1-2 times daily, every patch is 1 course for the treatment of with 1 day, 14 days.
Clinical test 1
1 clinical data
1.1 general information
All cases are our hospital's orthopaedics protrusion of lumber intervertebral disc patient 120, wherein male 57, female 63;Age 30 ~ 79 years old, disease 1 week ~ 12 anniversary of journey;Meet the Diagnosis of Lumber Disc Prolapse standard in " disease of tcm Standardization of diagnosis and curative effect ", through CT or MRI It is diagnosed as protrusion of lumber intervertebral disc.L3 ~ L4 protrusion of lumber intervertebral disc 12, L4 ~ L5 protrusion of lumber intervertebral disc 45, L5 ~ S1 lumber ertebral disc It is 22 prominent.Patient source Shijiazhuang District town and country, patient symptom sign is checked by CT examination, MRI, meets lumber ertebral disc Herniation diagnosis.
1.2 cases are included in standard
(1) meet diagnostic criteria, the person of clarifying a diagnosis;(2) between 30-79 years old, male or female;(3) informed consent is volunteered tested Person.
1.3 case exclusion criterias
(1) diseases such as serious cardiovascular and cerebrovascular or liver kidney, severe infection person are associated with;(2) tuberculosis of lumbar spine, tumor patient;(3) With phrenoblabia, rheumatism, rheumatoid, gout and serious heart and brain kidney diaseases person;(4) gestational period and breast feeding women;(5) Because a variety of causes interrupts curer.
2 treatment methods
2.1 Chai Shi bone fracture plasters
The rules for the treatment of: inducing diuresis for removing edema is removed obstruction in channels to relieve pain, promoting the circulation of qi dissolving stasis.The plaster that embodiment 1 obtains is given, applys and applies a hot compress to the affected part, every time 14 Hour, one time a day, every patch is 1 course for the treatment of with 1 day, 14 days.
2.2 points for attention
1. not scalding, preferably keep warm, wind sheltering is cold;2. patient has wound, person should not be used;3. local anaphylaxis person stops treatment;4. dividing Curative effect is not evaluated in the 1st, the 2nd course for the treatment of;5. disabling anti-inflammatory analgesic or other physical therapy measures during treatment.
3 observation of curative effect
3.1 observation index
120 patients with pretherapy and post-treatment reference the credibility of pain in the loins patient " Disability index evaluation " (Chinese spine and spinal cord Magazine, 2002,12(1): 13.) to include pain (influence of pain degree, pain to sleep), individual event function (mention/take object, Seat is stood, walking) and 3 aspect of personal comprehensive function (daily activities, social activities and outing), 9 functions progress The evaluation of Oswestry Disability index (ODI), ODI score (accumulative point/45 × 100% i.e. practical), the higher pain of score Degree is more serious.Statistical procedures carry out t inspection using SPSS15.0 statistics software.
3.2 curative effect determinate standard
Referring to relevant criterion in " new Chinese medicine clinical guidance principle ".Cure: clinical symptoms and sign disappear, leg raising straight examination It tests and is greater than 70 °, functional rehabilitation is normal;Improve: clinical symptoms and sign disappear or mitigate substantially, and functional activity is close to normally;Nothing Effect: clinical symptoms and sign are not improved.
3.3 treatment results
In 120 patients, 59 are cured, is improved 47, invalid 14, total effective rate 86.67%.Before and after treatment The evaluation result of Oswestry Disability index is shown in Table 1.
The pretherapy and post-treatment ODI of table 1 120 scoring situation compares ± s, %
Time n Improve
Before treatment 120 51.30±13.08
After treatment 120 28.66±9.35*
P < 0.05 * compared with before treatment
3.3.1 the safety for the treatment of
It observes except 1 skin allergy has fash in 120 patients, disappears quickly after stopping treatment outer, remaining is not incumbent out What side effect.
Clinical test 2
1 data and method
1.1 general information
Choose in December, 2016 our hospital's private prosecution in December, -2017 waist have damage with history of pain patient 120, after CT is detected It is diagnosed as lumbar vertebrae and asks disc protrusion, be randomly divided into two groups each 60.Treatment group male 41, women 19;Age 27~69 is (flat Equal 42.36) year;The course of disease 3 months~13 years.Simple pain in the loins 30, simple skelagia 10, pain in the loins and skelagia 20, wherein 21 With skin of lower extremity stolidity, CT shows that L4-L5 is 32 prominent, and L5-S1 protrusion person 17, two sections are all 11 prominent, outside rear profile It is 36, Central protrusion 24 prominent.Control group male 38, women 22;Age 29~65 (average 40.12) year;The course of disease 2 A month~11.8.Simple pain in the loins 23, simple skelagia 16, pain in the loins and skelagia 21, wherein 18 are felt with skin of lower extremity Numbness, CT show that L4-L5 is 30 prominent, and L5-S1 protrusion person 16, two sections are all 14 prominent, and outside rear profile is 31 prominent, center Prominent 29, type, two groups of gender, age, the course of disease, symptom compare P > 0.05, are comparable.All patients exclude other diseases Pain in the loins caused by disease, pregnancy and nursing period, serious cardiovascular and cerebrovascular disease, liver and kidney disease person.
1.2 diagnostic criteria draft following diagnosis according to " lumbar vertebrae asks disc protrusion " and Standards for Diagnosis and Curative Effect of Chinese Medical Symptom Standard: 1. flank pain and to lower limb radiate;2. pain locally has obvious tender point;3. straight-leg raising test is positive;4. skin Stolidity or ant sting sense, and muscular strength, tendon reflex change;5. spine posture changes;6. CT prompt has lumbar intervertebral disc bulge.
1.3 treatment method
Treatment group: being pasted on lumbar vertebrae protruding parts using Chai Shi plaster prepared by 2 method of embodiment, and 14 hours every time, daily 1 Secondary, every patch is 1 course for the treatment of with 1 time, 14 days.It is not required to lie up during treatment, manual labor in power can be carried out in right amount.
Control group: being treated using electromagnetic wave curing instrument, irradiates waist and huckle, 30min is each, 2 times a day, is within 14 days 1 course for the treatment of treats 2 courses for the treatment of altogether, it is proposed that lies up, reduces manual labor.
1.4 efficacy assessment standard
It is evaluated according to Macnab efficacy assessment standard.Recovery from illness: clinical symptoms completely disappear, and ability to work is restored completely, complete It does not influence to live entirely.It is effective: to there is pain in the loins or skelagia, intermittent slight pain in the loins or Rediating Pain to occur once in a while, but can restore substantially Ability to work does not influence quality of life.Invalid: pain, dermal sensation or muscular strength are even aggravated without improvement, nerve root injury sign The positive, ability of losing the job.Total effective rate=cure rate+obvious effective rate.
1.5 all data application SPSSl3.0 statistical softwares carry out statistical procedures, and enumeration data examined with x2, with P < 0.05 is statistically significant for difference.
2 results
2.1 two groups of curative effects compare, and treatment group fully recovers 29, and effective 20, invalid 11, total effective rate 81.67%, control group Recovery from illness 10, effective 34, invalid 19, total effective rate 68.33%, treatment group's curative effect is substantially better than control group, P < 0.01, With significant statistical difference.It is shown in Table 2.
2 treatment group of table and control group statistical result
Group Number of cases Recovery from illness Effectively In vain Total effective rate (%)
Treatment group 60 19(31.67) 30(50) 11(18.33) 81.67
Control group 60 10(16.67) 31(51.67) 19(31.67) 68.33
Clinical test 3
1 data and method
1.1 general information
To the patient for 100 protrusion of lumber intervertebral disc accepted for medical treatment during in May, 2017, all patients meet in August, 2015 " the disease of tcm Standardization of diagnosis and curative effect " promulgated in 2000 of diagnosis and exclusion in to(for) protrusion of lumber intervertebral disc.By above 100 Patient is randomly divided into study group and control group, and every group has patient 50.Study group male patient 30, female patient 20, Year at age (43.3 ± 1.8), the course of disease (6.5 ± 0.9) year;Control group male patient 34, female patient 16, the age (42.5 ± 1.9) year, the course of disease (6.8 ± 1.2) year, not significant through two groups of patient's general information differences of comparative analysis, between can carry out Compare.This clinical application scheme patient has right to know, and signs informed agreement with us.
1.2 diagnostic criteria
Referring to " disease of tcm Standardization of diagnosis and curative effect ", cure: the symptom of lumbocrural pain disappears, and can restore positive work, straight legs Portion is raised above 70 °;Improve: the symptom of lumbocrural pain mitigates, and the activity of waist and lower limb is apparent to be improved;Invalid: clinic is treated Effect and quality of life do not reach more than standard.Totall effective rate in clinical treatment+(healing+improvement)/total number of cases * 100%.
1.3 treatment method
Control group: the prominent plaster of Chai Shi waist removes Chinese ephedra, with asarum 30g, lepidium seed 30g, semen brassicae 75g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.It is applied a hot compress to the affected part with above-mentioned plaster, 14 hours every time, one time a day, every patch was 1 course for the treatment of with 1 day, 14 days.
Study group: Chai Shi waist is dashed forward plaster: Chinese ephedra 50g, asarum 30g, lepidium seed 30g, semen brassicae 75g, rhizoma corydalis 80g, sweet Careless 80g, Radix Astragali 150g, are applied a hot compress to the affected part with above-mentioned plaster, and 14 hours every time, one time a day, every patch was 1 course for the treatment of with 1 day, 14 days.
1.4 evaluate pain degree using VAS method before and after treatment, and score is higher to illustrate that pain is more obvious
1.5 two groups of statistical is completed in SPSS20.0, and metering is examined with t, and enumeration data Chi-square Test is compared P < 0.05 indicates significant difference afterwards.
2 results
The statistical result of 2.1 study groups and control group is shown in Table 3.
The statistical result of table 3 study group and control group
Group Number of cases It cures It improves In vain Total effective rate (%)
Study group 50 17(34.0) 23(46.0) 10(20.0) 80.0
Control group 50 13(26.0) 16(32.0) 21(42.0) 58.0
2.2 two groups of curative effects compare, and study group's totall effective rate in clinical treatment is 80.0%, and control group 58.0%, two groups poor It is different significant, it specifically the results are shown in Table 4.
4 two groups of Clinical efficacy comparisons of table [n (%)]
2 value of Χ 4.6751
P value <0.05
The VAS score of two groups of patients reduces after 2.3 pretherapy and post-treatment two groups of VAS compare treatment, and study group reduces result It is significantly better than control group, specifically the results are shown in Table 5.
(x- ± s divides) is compared in 5 pretherapy and post-treatment two groups of VAS scorings of table
Time Study group Control group T value P value
Before treatment 6.3±1.0 6.2±1.4 0.05 >0.05
After treatment 2.0±0.9 2.8±1.1 1.06 <0.05
T value 1.36 1.19 - -
P value <0.05 <0.05 - -
Clinical test 4
1 data and method
1.1 general information
Totally 90, it is the patient that 2 months 2016 to 2 months 2017 our hospital accept for medical treatment, is randomly divided into treatment group and control group each 45 Example.Treatment group male 28, female 17, the age 35 ~ 74 years old, the course of disease 5 months ~ 8 years.Control group male 27, female 18, the age 37 ~ 70 years old, the course of disease 7 months ~ 7 years.Two groups of genders, age, courses of disease etc. compare difference and look like (P > 0.05) without statistics, have Comparativity.
1.2 diagnostic criteria
The protrasion of the lumbar intervertebral disci examines in reference " clinic diagnosis guide-orthopaedics fascicle " (people's health version society, 2009:97-99.) Disconnected standard and Standards for Diagnosis and Curative Effect of Chinese Medical Symptom (publishing house, Nanjing University, 1994:202.) protrasion of the lumbar intervertebral disci are examined Disconnected foundation, syndrome-classification.
1.3 treatment method
Control group: the prominent plaster of Chai Shi waist removes lepidium seed, with asarum 30g, Chinese ephedra 50g, semen brassicae 75g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.It is applied a hot compress to the affected part with above-mentioned plaster, 14 hours every time, one time a day, every patch was 1 course for the treatment of with 1 day, 14 days.
Treatment group: Chai Shi waist is dashed forward plaster: Chinese ephedra 50g, asarum 30g, lepidium seed 30g, semen brassicae 75g, rhizoma corydalis 80g, sweet Careless 80g, Radix Astragali 150g, are applied a hot compress to the affected part with above-mentioned plaster, 8-14 hours each, 1-2 times daily, and every patch is 1 with 1 day, 14 days The course for the treatment of.
1.4 criterion of therapeutical effect
Recovery from illness: lumbocrural pain disappears, and 70 ° of leg raising straight or more, somatic feature score mitigates 95%.Effective: lumbocrural pain disappears substantially, 50 ° of straight-leg raising test or more, somatic feature score mitigates 70% ~ 95%.Effective: lumbocrural pain mitigates, and waist movable function improves, body Sign integral mitigates 30% ~ 70%.Invalid: without improvement, somatic feature score mitigates less than 30% for symptom, sign
1.5 are analyzed with SPSS13.0 software package, and enumeration data is examined using X2, and measurement data is examined using t, and P < 0.05 is Difference is statistically significant.
2 treatment results
Two groups of Clinical efficacy comparisons are shown in Table 6.
6 two groups of Clinical efficacy comparisons (%) of table
Grouping Example Recovery from illness It is effective Effectively In vain Total effective rate
Treatment group 45 14 15 10 6 (86.67)
Control group 45 8 7 19 11 (75.56)
Note: X2=8.8091 compared with the control group, P < 0.05.
Typical case 1
Tang XX gender 43 years old age at noon of female occupation worker's admission time August in 2018 09:03 on the 4th;Discharge time August 18 in 2018 Day, 10:00 was hospitalized 14 days altogether.
Be admitted to hospital situation: patient's main cause pain in the loins part vola is numb, is admitted to hospital within limitation of activity 2 weeks.Primary symptom when being admitted to hospital, flank pain, Vola is numb, limitation of activity.Without afternoon low-heat, night sweat out of strength, no waist is tetanic etc..Recently receive can, sleep and feel unwell, two just adjust.Tongue Matter is dark, and coating colour is white, and coating nature is thin, pulse condition string.Stretched: T36.2C, P72 beat/min, R18 beats/min, Bp124/69mmHg, lumbar vertebrae is raw It manages curvature to exist, back muscle tonue, tenderness (+) between L3-S1 spine and by spine kowtows pain (+), Rediating Pain (+).Bilateral pyriformis tenderness (+), Rediating Pain (+).A straight-leg raising test left side 50 ", it is 50 ° right.Yue vertebra mobility:, extending back 20 ° by anteflexion 60 °, and 20 ° of left side Lee, Right lateral bend 20 ", left-handed 20 ", dextrorotation 20*.5 grades of double lower limb muscular strength, Muscle tensility, dermal sensation are shown no obvious abnormalities.Physiological reflex In the presence of pathologic reflex is not drawn.
Diagnosis and treatment by: auxiliary examination is improved after being admitted to hospital;Lumber ertebral disc CT: consider that waist 4-5 interverbebral disc slightly protrudes.Blood is normal Rule: NEUT76. 4%, LYMPH18. 7%, E00. 3%, NEUT6. 86*10 9/L, HGBI12g/L, MCH26. 4pg.It is biochemical Quan Xiang: AST/ALT2. 03, Apo-A1. 62mol/L. five indexes of hepatitis b, rheumatism three fixed most measurements, erythrocyte sedimentation rate (ESR) measurements (ESR) Non Apparent Abnormality.Tumour nine: CEA4. 43ng/ml, Ferritin9. 51ng/m1.
Admission diagnosis: tcm diagnosis: waist numbness disease syndrome of blood stasis and stagnant qi.
Doctor trained in Western medicine diagnosis: protrusion of lumber intervertebral disc.
It is treated after being admitted to hospital: giving externally applied ointment of the present invention, apply a hot compress to the affected part, it is 14 hours every time, one time a day, every to paste with 1 day, 14 are 1 course for the treatment of.
Discharge situation: through treating: patient's waist pain, vola numbness mitigate, and limitation of activity improves.Without afternoon low-heat, weary Power night sweat, no waist are tetanic etc..Recently receive can, peace of sleeping, two just adjust.Dark tongue quality, coating colour is white, and coating nature passes, pulse condition string.Patient is general Situation can, the clear language benefit of mind, in body cooperation.Physical examination: lumbar physiological-curvature exists, back muscle tonue.Back muscle tonue, L3-S1 spine Between and spine by tenderness (-), kowtow pain (-), Rediating Pain (-).Bilateral pyriformis tenderness (-), Rediating Pain (-).Straight-leg raising test is left It is 50 °, 50 ° right.Lumbar vertebrae mobility: anteflexion 60 °, 20 ° are extended back, curved 20 °, 20 ° of right lateral bend, left-handed 20 °, 20 ° of dextrorotation of left side.It is double 5 grades of lower-limb muscular strength, Muscle tensility, dermal sensation are shown no obvious abnormalities.Physiological reflex exists, and pathologic reflex is not drawn.
Discharge instructions: 1. wind shelterings are cold, regulating spirit and emotion by oneself, having regular daily life, temperance for food and drink, fit movement.2. abnormal index is checked after 1 week, Uncomfortable follow-up.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although Present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: it still may be used To modify to technical solution documented by previous embodiment or equivalent replacement of some of the technical features;And These are modified or replaceed, the spirit and model of technical solution of the embodiment of the present invention that it does not separate the essence of the corresponding technical solution It encloses.

Claims (6)

1. a kind of Chinese medicinal ointment for treating the protrasion of the lumbar intervertebral disci, which is characterized in that it is made of following raw material: Chinese ephedra 40-50g, asarum 20-30g, lepidium seed 20-30g, semen brassicae 60-80g, rhizoma corydalis 70-80g, Radix Glycyrrhizae 70-80g, Radix Astragali 140- 150g。
2. a kind of Chinese medicinal ointment for treating the protrasion of the lumbar intervertebral disci according to claim 1, which is characterized in that it is by as follows Raw material is made: Chinese ephedra 40g, asarum 30g, lepidium seed 30g, semen brassicae 80g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
3. a kind of Chinese medicinal ointment for treating the protrasion of the lumbar intervertebral disci according to claim 1, which is characterized in that it is by as follows Raw material is made: Chinese ephedra 50g, asarum 20g, lepidium seed 20g, semen brassicae 60g, rhizoma corydalis 70g, Radix Glycyrrhizae 70g, Radix Astragali 140g.
4. a kind of Chinese medicinal ointment for treating the protrasion of the lumbar intervertebral disci according to claim 1, which is characterized in that it is by as follows Raw material is made: Chinese ephedra 50g, asarum 30g, lepidium seed 30g, semen brassicae 75g, rhizoma corydalis 80g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
5. a kind of Chinese medicinal ointment for treating the protrasion of the lumbar intervertebral disci according to claim 1, which is characterized in that it is by as follows Raw material is made: Chinese ephedra 50g, asarum 20g, lepidium seed 30g, semen brassicae 60g, rhizoma corydalis 70g, Radix Glycyrrhizae 80g, Radix Astragali 150g.
6. a kind of preparation method of the described in any item traditional Chinese medicine plasters of the claims 1-5, which is characterized in that weigh above-mentioned each Raw material is ground into powdery, and the above powder of Chinese herbs is added in 60 ~ 80 DEG C of pockmarks oil vessels of preheating, is heated to 250 ~ 350 DEG C, stirring Lead powder is added, 60 ~ 80 DEG C are cooled to after herb powder is merged with lead powder, stops stirring when paste is presented in container, it will Paste is contained to cover into the small container got ready in advance, deposits in and is protected from light, is spare at dry and ventilated, makes it with micro-wave oven when use It is heated to 60 ~ 80 DEG C to take in right amount, then wraps up in and affected part is spread on cloth or gauze.
CN201811310566.9A 2018-11-06 2018-11-06 A kind of traditional Chinese medicine plaster and preparation method thereof for treating the protrasion of the lumbar intervertebral disci Pending CN109662995A (en)

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Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
卢璐等: "天灸治疗腰椎间盘突出症之腰痛的临床疗效研究"", 《中国全科医学》 *
王付: "《疑难杂病 八大证治》", 31 July 2017, 河南科学技术出版社 *
绝技秘方: "黄芪外洗根除腰椎间盘突出症", 《HTTP://BLOG.SINA.COM.CN/S/BLOG_493A723C01011C96.HTML》 *
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Application publication date: 20190423