CN109640855A

CN109640855A - Lung cancer therapy electrode catheter

Info

Publication number: CN109640855A
Application number: CN201780049724.7A
Authority: CN
Inventors: 森谦二
Original assignee: Japan Lifeline Co Ltd
Current assignee: Japan Lifeline Co Ltd
Priority date: 2016-11-10
Filing date: 2017-05-10
Publication date: 2019-04-16
Also published as: WO2018087948A1; JP2018075209A; JP6671077B2

Abstract

The purpose of the present invention is to provide the outer diameter variation that can make electrode and along the bronchial circumferential lung cancer therapy electrode catheter for carrying out uniform burn treatment.It has: catheter shaft (10)；Electrode (20), is fixed on the front end of catheter shaft (10), and the metal tube (M1) by being axially formed multiple slits (21) is constituted, and radially expands if axially compressed and is formed as basket shape；Front end blade (25), is fixed on the front end of electrode (20)；Operation handle (30), is fixed on the cardinal extremity of catheter shaft (10)；Conducting wire (40), connect and the internal stretch in catheter shaft (10) with electrode (20)；Temperature sensor (50) has the thermometric portion (55) for being fixed on electrode (20) and the internal stretch in catheter shaft (10)；Cable (60) are used in operation, are had and are fixed on the front ends (61) of front end blade (25), can axially inside movably extending in catheter shaft (10), cardinal extremity can be stretched operation.

Description

Lung cancer therapy electrode catheter

Technical field

The present invention relates to lung cancer therapy electrode catheters, relate to burn cancer cell by high frequency conduction in more detail Lung cancer therapy electrode catheter.

Background technique

In recent years, the treatment method as the lung cancer for replacing surgical treatment, the method that cancer cell is burnt by high frequency conduction It is attracted attention, as the equipment for such burn treatment method, proposition has the electrode for having temperature sensor (thermocouple) Conduit (referring to following patent documents 1).

Usage mode as lung cancer therapy electrode catheter can enumerate following manner, it may be assumed that prop up guide sleeves insert In the channel of airway wall (endoscope), lung cancer therapy is inserted through with electrode catheter and is extended from the front opening of bronchoscope The lumen of guide sleeves makes the preceding termination electrode of the lung cancer therapy electrode catheter extended from the front end of guide sleeves reach therapy section Position, the preceding termination electrode and attach patient body surface between pole plate connect high-frequency current and burn lung carcinoma cell.

Patent document 1: Japanese Unexamined Patent Publication 8-308853 bulletin

In lung cancer therapy electrode catheter as described above, in order to be inserted through it in channel of bronchoscope, and make Its preceding termination electrode reaches the bronchus (bronchiole) of tip, becomes with needing the outer diameter degree for making catheter shaft and preceding termination electrode Carefully.

However, can not be using the lung cancer therapy electrode catheter for the preceding termination electrode for having such thin footpath to appearing in thick branch The cancer cell of tracheae carries out sufficient burn treatment, such as the cancer cell that (complete cycle) occurs around main bronchus, only The cancer cell of the near sites of termination electrode contact before capable of burning.

Summary of the invention

The present invention is made based on above such situation.

The first object of the present invention is that electrode can be made according to the bronchial thickness of therapentic part by providing one kind Outer diameter variation, can be along the bronchial circumferential lung cancer therapy electrode catheter for carrying out uniform burn treatment.

The second object of the present invention is that provide a kind of can burn goes out in the bronchus (bronchiole), alveole of tip Existing cancer cell, and can to as main bronchus it is thick it is bronchial around (complete cycle) appearance cancer cell along the branch The lung cancer therapy electrode catheter that the circumferential direction of tracheae is equably burnt.

(1) lung cancer therapy of the invention has with electrode catheter:

Catheter shaft；

The electrode of high frequency conduction is fixed on the front end of the catheter shaft, by be formed with axially extend it is multiple narrow The metal tube of seam is constituted, and when axially compressed, the slit is opened and radially expanded, and is deformed by multiple protrusions The basket shape of composition；

Front end blade is fixed on the front end of the electrode；

Operation handle is fixed on the cardinal extremity of the catheter shaft；

Conducting wire is electrically connected and in the internal stretch of the catheter shaft with the electrode；And

Operation cable, has the front end for being fixed on the front end blade, can be on the inside edge of the catheter shaft Axially movably extend, cardinal extremity can be stretched operation.

Electrode catheter according to such composition, due to being made of the metal tube for being formed with the multiple slits axially extended Electrode, therefore the outer diameter of electrode when undergauge can be made sufficiently to reduce, the electrode can be made to reach bronchus (the ramuscule gas of tip Pipe), the cancer cell occurred in bronchiole, alveole can be burnt.

In addition, stretched operation is carried out with cable to operation, to electrode (metal tube for being formed with multiple slits) along axial pressure Contracting, thus the electrode radially expands and is deformed into basket shape.Thus it enables that the outer diameter (maximum diameter) of electrode when expanding fills Point become larger, can to as main bronchus it is thick it is bronchial around (complete cycle) appearance cancer cell along the bronchial week To equably being burnt.

In addition, constituting the protrusion of the electrode (electrode of basket shape) when expansion, the slit by being formed in metal tube is beaten Open and the tube wall of the metal tube circumferentially be divided and formed, even therefore thin footpath metal tube can also be reliably formed it is more A protrusion, thus, it is possible to along the bronchial circumferential uniform burn treatment of progress.

(2) in electrode catheter of the invention preferably, the metal tube be configured to include:

Electrode composition part is formed with the slit axially extended；With

Axis composition part is covered by insulation in the base end side of the electrode composition part, and constitutes the catheter shaft,

Spiral helicine slit or slot are formed in the axis composition part.

Electrode can be firmly secured to the front end of catheter shaft by electrode catheter according to such composition, and can It is formed with spiral helicine slit or slot in the axis composition part of metal tube, thus, it is possible to substantially ensure the front end portion of catheter shaft Flexible, flexibility.

(3) in electrode catheter of the invention preferably, the catheter shaft is in the axis constituting portion than the metal tube Divide the position by base end side that there is multi-cavity configuration.Electrode catheter according to such composition, can make operation cable, conducting wire with And temperature sensor does not interfere, and in the internal stretch of catheter shaft.

(4) in electrode catheter of the invention preferably, the outer diameter of the catheter shaft is 2.0mm or less.

Catheter shaft can be inserted through in the channel of bronchoscope by electrode catheter according to such composition, and can The electrode for the front end for being fixed on catheter shaft is set reliably to reach the bronchus (bronchiole) of tip.

(5) in electrode catheter of the invention preferably, it is formed in the slit of the metal tube axially extended Quantity be 6 or more.

Electrode catheter according to such composition reliably can uniformly burn along bronchial circumferential progress and control It treats.

(6) in electrode catheter of the invention preferably, have temperature sensor, there is the survey for being fixed on the electrode Warm portion and in the internal stretch of the catheter shaft, the thermometric portion of the temperature sensor is by being formed with spiral helicine slit Collapsible tube and be fixed on the inner circumferential side for constituting at least 1 protrusion of the electrode and be fixed on and be equivalent to the electrode The position in maximum diameter portion.

Electrode catheter according to such composition can reliably measure the position (bronchus of electrode (protrusion) contact Inner wall) temperature.

In addition, by using the collapsible tube of spiral helicine slit is formed with, even if the slit being thus axially formed does not have The end for reaching metal tube, can also make the collapsible tube be wound in protrusion, therefore can be reliably by the survey of temperature sensor Protrusion is fixed in warm portion.

(7) in electrode catheter of the invention preferably, the formation of the metal tube has the slit axially extended Part front-end side region and rear-end side region by insulation cover, thus only to the middle area clipped by described two regions Domain carries out high frequency conduction.

Electrode catheter according to such composition only carries out high frequency conduction to the intermediate region of basket, therefore is able to suppress The loss of high-frequency energy.

(8) in electrode catheter of the invention preferably, the electrode has: front end side conical portion, straight trunk with And rear end side conical portion,

The multiple slits for being formed in the metal tube are axially extended in the straight trunk respectively, and before described End side conical portion is tilted to radially inner side and extreme direction extends forward, is inclined in the rear end side conical portion to radially inner side Tiltedly and backward extreme direction extends,

When the electrode is axially compressed, the electrode is in the axial straight line for constituting the tube wall of the straight trunk Property be maintained, and the slit open and radially expand, be deformed into the basket shape being made of multiple protrusions.

Electrode catheter according to such composition makes the straight trunk of electrode abut (face contact) with bronchial inner wall, Thus along the bronchial circumferential direction and uniform burn treatment can not only be carried out along axial.

(9) in the electrode catheter of above-mentioned (8) preferably, the front end side conical portion of the metal tube and described Rear end side conical portion is covered by insulation, and thus only carrying out high frequency conduction to the straight trunk, (the straight trunk becomes high frequency The electrode of energization).

Electrode catheter according to such composition only carries out high frequency conduction to the straight trunk of basket, therefore is able to suppress The loss of high-frequency energy.

(10) electrode catheter of the invention is preferably inserted through in the channel of bronchoscope and uses.

Lung cancer therapy electrode catheter of the invention can make the outer of electrode according to the bronchial thickness of therapentic part Diameter (maximum diameter) variation, can be along the bronchial circumferential uniform burn treatment of progress.

In addition, can occur in the bronchus (bronchiole), alveole of tip using the cauterizing electrode of undergauge state Cancer cell, and electrode can be kept expanding and carrying out stretched operation with cable to operation, thus to such in main bronchus It is thick it is bronchial around (complete cycle) occur cancer cell equably carry out burn treatment along the bronchial circumferential direction.

Detailed description of the invention

Main view when Fig. 1 is the electrode undergauge of the electrode catheter of first embodiment.

Fig. 2 is the main view when electrode of the electrode catheter of first embodiment is expanding.

The main view of main portions when Fig. 3 is the electrode undergauge for indicating the electrode catheter of first embodiment.

Fig. 4 is the IV-IV cross-sectional view of Fig. 3.

Fig. 5 is the main view for indicating the main portions when electrode of the electrode catheter of first embodiment is expanding.

Fig. 6 is the VI-VI cross-sectional view of Fig. 5.

Fig. 7 is the VII-VII cross-sectional view of Fig. 5.

Fig. 8 A is the VIIIA-VIIIA cross-sectional view of Fig. 5.

Fig. 8 B is the VIIIB-VIIIB cross-sectional view of Fig. 5.

Fig. 9 is that the portion IX of Fig. 6 schemes in detail.

Figure 10 is the X-X cross-sectional view of Fig. 5.

Figure 11 is that the portion XI of Figure 10 schemes in detail.

Figure 12 is that the portion XII of Fig. 6 schemes in detail.

Figure 13 is the perspective view for indicating for be fixed in the thermometric portion of temperature sensor the state of protrusion.

The explanatory diagram of main portions when Figure 14 is the electrode undergauge for indicating the electrode catheter of second embodiment, (a) are Main view, (b) be (a) XIVB-XIVB cross-sectional view.

Figure 15 is the explanatory diagram for indicating the main portions when electrode of the electrode catheter of second embodiment is expanding, and (a) is Main view, (b) be (a) XVB-XVB cross-sectional view.

Figure 16 is the explanatory diagram for indicating the main portions when electrode of the electrode catheter of third embodiment is expanding, and (a) is Main view is (b) that the portion XVIB of (a) schemes in detail.

Specific embodiment

< first embodiment >

The lung cancer therapy electrode catheter 100 of present embodiment shown in Fig. 1~Figure 13 has: catheter shaft 10；High frequency is logical The electrode 20 of electricity, is fixed on the front end of catheter shaft 10, by being formed with axially extend 16 slits 21 in undergauge Metal tube M1 is constituted, and when axially compressed, slit 21 is opened and radially expands (expanding), is deformed into and is opened by slit 21 So that the tube wall of metal tube M1 is divided and the basket shape of 16 protrusions 23 composition of formation；Front end blade 25, is fixed on The front end of electrode 20；Operation handle 30 is fixed on the cardinal extremity of catheter shaft 10；Conducting wire 40 is electrically connected and is being led with electrode 20 The internal stretch of pipe axis 10；Temperature sensor 50 has the thermometric portion 55 for being fixed on electrode 20 and in the inside of catheter shaft 10 Extend；And operation cable 60, there is the front end 61 for being fixed on front end blade 25, it can be on the inside edge of catheter shaft 10 Axially movably extend, cardinal extremity can be stretched operation.

The catheter shaft 10 of the electrode catheter 100 of present embodiment is constituted by base end part 11, front end 12 and front end portion 13 are constituted.

As shown in Figure 8A and 8B, the base end part 11 of catheter shaft 10 and front end 12 are by inside 17 and covering internal 17 Outside 18 formed, be formed with central lumen 15 in the inside 17 of base end part 11 and front end 12, and formed around it There is sub- lumen 161~168.

Operation cable 60 extends in central lumen 15, and conducting wire 40 extends in sub- lumen 161, and temperature sensor 50 exists Extend in sub- lumen 165.

As shown in Figure 8 B, it has been incorporated into braided fabric 19 in the outside of base end part 11 18, has been incorporated into the base end part 11 of braided fabric 19 (woven tube) is that have component that is flexible and having both rigidity to a certain degree, and thus electrode catheter 100 becomes with good The component of promotion ability and torque transitivity.

Constituent material as base end part 11 and front end 12 is able to use polyolefin, polyamide, polyether-polyamide, gathers The synthetic resin such as urethane, nylon, polyether block amide (PEBAX), the PEBAX being able to use in them.

In addition, the constituent material of the braided fabric 19 as the outside 18 for being programmed into base end part 11 can be enumerated by embedded And the metal or resin material of reinforcing effect can be played.

Hardness as the resin for constituting base end part 11 is usually 55D~80D, preferably 63D~75D.

Hardness as the resin for constituting front end 12 is usually 25D~55D, preferably 30D~45D.

As shown in Fig. 7 and Fig. 9, the cardinal extremity of the metal tube M1 linked with front end 12 in the front end portion 13 of catheter shaft 10 Part is insulated by resin layer 14 to be covered.

It is formed with spiral helicine slit 131 in the base end portion (axis composition part) of metal tube M1, before thus ensuring most The flexibility (flexibility) of end 13.

The spacing of spiral helicine slit 131 narrows towards preceding extreme direction, and thus, it is possible to realize the raising of operability.

Length as catheter shaft 10 is usually 1100~2000mm, is 1200mm if showing a preferred example.

In addition, the length of base end part 11 (woven tube of multi-cavity configuration) is usually 900~1970mm, if showing preferred one A example is then 1120mm.

In addition, the length of front end 12 (the non-woven pipe of multi-cavity configuration) is typically set to 30~200mm, if showing preferred One example is then 80mm.

In addition, the length in front end portion 13 is usually 10~40mm, it is 25mm if a preferred example is shown.

The outer diameter of catheter shaft 10 is preferably 2.0mm hereinafter, more preferably 1.7mm is hereinafter, if show a preferred example It is then 1.35mm.

If the catheter shaft 10 of such thin footpath, then can be inserted through in the channel of bronchoscope (using guide sleeves In the case of, for the lumen of the guide sleeves), in addition, the branch for the electrode arrival tip for being configured at the front end of the catheter shaft 10 can be made The therapentic part of tracheae (bronchiole), alveole.

Constitute the electrode 20 of the high frequency conduction of the electrode catheter 100 of present embodiment, when undergauge axially extend 16 Slit 21 is made of the metal tube M1 for being circumferentially equiangularly spaced formation.

As shown in Fig. 1, Fig. 3 and Fig. 4, the shape of the electrode 20 when undergauge is cylindric.

16 slits 21 for being formed in electrode 20 (the electrode composition part of metal tube M1) are circumferentially equiangularly spaced (22.5 ° of intervals) is formed.

In addition, 16 slits 21 are mutually formed in identical axial position, the front end and rear end of 16 slits 21 less than Up to the front end and rear end of metal tube M1.

If the electrode 20 of undergauge state is axially compressed, each slit 21 is opened and makes the electrode 20 (metal tube M1 Electrode composition part) radially expand.

At this point, being opened by each slit 21 is divided into the tube wall of the metal tube M1 of electrode composition part circumferentially 16 parts, the electrode 20 that 16 protrusions are consequently formed is deformed into basket shape.

In the electrode catheter 100 of present embodiment, the shape of the electrode 20 when expansion is shown in Fig. 2, Fig. 5 and Fig. 6 Ellipse it is spherical (using the pipe axis of metal tube M1 as the ellipsoid of revolution of rotary shaft), axial central location is as maximum diameter Portion.

Additionally, it is preferred that the electrode 20 of undergauge state is not complete cylindrical position, protrusion 23 is become when expanding The slightly outside lateral bend in the central location of tube wall and become intermediate high shape.

As a result, when compressing the electrode 20, a part of the tube wall part of Ying Chengwei protrusion 23 is not curved to the inside, and It is that can reliably expand and become elliptical shape ball shape.

Roughly same outer diameter with catheter shaft 10 for the outer diameter of electrode 20 when undergauge.

The thinning of electrode 20 when undergauge can be realized for the first time and constituting electrode 20 by metal tube M1.

The outer diameter (maximum diameter of basket shape electrode) of electrode 20 when expansion is preferably 1.35mm or more, and more preferably 1.5 ~2.0mm is 1.6mm if showing a preferred example.Thereby, it is possible to make the maximum diameter portion of electrode 20 and main bronchus that The thick bronchial inner wall contact of sample, can equably burn around this is bronchial the cancer cell of (complete cycle) appearance.

The wall thickness (thickness of protrusion 23) of tube wall as the metal tube M1 for constituting electrode 20 be preferably 0.3mm hereinafter, More preferably 0.02~0.2mm is 0.05mm if showing a preferred example.

In the case where the wall thickness is blocked up, the outer diameter of metal tube when contraction is excessive, it is difficult to electrode 20 be made to reach tip The therapentic part of bronchus (bronchiole), alveole.

Constituent material as electrode 20 (metal tube M1) is able to use the preceding termination electrode with known ablation catheter Identical material.

Specifically, the high platinum of x-ray imaging, gold, platinum-iridium alloy etc. can be enumerated, but as preferred material energy Enough enumerate Ni-Ti alloy.

It is fixedly arranged at the front end with front end blade 25 in electrode 20, the front end 61 of cable 60 is used in the front end of electrode 20 and operation Link via the front end blade 25.

Constituent material as front end blade 25 can enumerate platinum, gold, platinum-iridium alloy etc..

As shown in Figure 1 and Figure 2, operation handle 30 is fixed in the cardinal extremity of catheter shaft 10.

The operation handle 30 for constituting the electrode catheter 100 of present embodiment is that have handle main body 31 and with grips The operation portion of 32 swivel plate 33.

As shown in figure 9, the inner peripheral surface in the base end portion (axis composition part) for the metal tube M1 for constituting electrode 20 passes through not The front end of the fixed conducting wire 40 of the scolding tin of diagram, thus conducting wire 40 is electrically connected with electrode 20.

The conducting wire 40 for constituting the electrode catheter 100 of present embodiment extends in the inside (sub- lumen 161) of catheter shaft 10, and It is connected to the inside of operation handle 30.In addition, the base end part of conducting wire 40 is connect with the connector being installed on inside operation handle 30.

1 protrusion 231 as shown in Figure 10~Figure 13, in 16 protrusions 23 of the electrode 20 when constituting expansion The central location (the comparable position in maximum diameter portion with electrode 20) of the length direction of inner circumferential side and the protrusion 231, passes through receipts The draw 57 is fixed with the thermometric portion 55 for the temperature sensor 50 being made of thermocouple.

In the central location (position in the maximum diameter portion of the electrode 20 when being equivalent to expansion) of the length direction of protrusion 231 Configured with thermometric portion 55, thus, it is possible to reliably measure the position (bronchial inner wall) of electrode 20 (protrusion 231) contact Temperature.

Temperature sensor 50 enters the inside in catheter shaft 10 (front end portion 13) along the inner circumferential side of protrusion 231, is leading The inside (sub- lumen 165) of pipe axis 10 extends and is communicated to the inside of operation handle 30.The base end part and peace of temperature sensor 50 Connector connection inside operation handle 30.

As shown in figure 13, in 57 shape of collapsible tube for the thermometric portion 55 of temperature sensor 50 to be fixed on to protrusion 231 At there is spiral helicine slit 59.

As has been described, before the front end and rear end for dividing the slit 21 of protrusion 231 do not reach metal tube M1 End and rear end (front end or rear end of protrusion 231 are not free ends).

Therefore, protrusion 231 can not be installed in common collapsible tube, if but being formed with spiral helicine slit 59 Collapsible tube 57, then 55 1 roll set of thermometric portion after becoming ribbon spiral shape and stretching to it, with temperature sensor 50 It is around in protrusion 231, thus it enables that the thermometric portion 55 is held in protrusion 231.

However, the collapsible tube 57 is shunk in the same manner as common collapsible tube by heating the collapsible tube 57, thus, it is possible to will The inner circumferential side of protrusion 231 is fixed in the thermometric portion 55 of temperature sensor 50.

As shown in figure 11, the thermometric portion 55 of temperature sensor 50 is fixed on grand in the state of being covered by the insulation of resin 58 Play the inner circumferential side in portion 231.Thus it when using electrode catheter 100 (when high frequency conduction), can prevent mutually made of metal Conducting between protrusion 231 and thermometric portion 55 (temperature sensor 50), result are able to carry out correct temperature measuring.

In addition, filling bonding agent in the inside (gap) for the collapsible tube 57 for being fixed with thermometric portion 55, or in collapsible tube 57 Surrounding coats bonding agent, and thus, it is possible to improve the consolidating relative to protrusion 231 (electrode 20) of thermometric portion 55 of temperature sensor 50 Determine power.

As shown in fig. 6, the front end 61 of cable 60 is used in the operation for constituting the electrode catheter 100 of present embodiment, by not The scolding tin of diagram and be fixed on front end blade 25, and enter inside (the front end portion of catheter shaft 10 by the inside of electrode 20 13), extend in the inside (central lumen 15) of catheter shaft 10 and be communicated to the inside of operation handle 30.

The swivel plate 33 of operation handle 30 is fixed in operation with the base end part of cable 60.

Constituent material as operation cable 60 can enumerate the metal materials such as superelastic alloy of stainless steel, Ni-Ti system Material, high-intensitive non-conductive material etc..

Stretched operation is carried out with the cardinal extremity of cable 60 to operation and rotating the swivel plate 33 of operation handle 30, thus Operation is mobile to base end side in the inside of catheter shaft 10 with cable 60, the fixed front end blade in the front end 61 of operation cable 60 25 is mobile to base end side, so that the electrode 20 of undergauge state is axially compressed.Thus the electrode composition part edge of metal tube M1 Radial dilatation, electrode 20 are deformed into the basket shape of oval spherical shape.

The electrode catheter 100 of present embodiment is inserted through in the channel as the bronchoscope of endoscope, visual Observation is lower to be used.

For example, guide sleeves are inserted through in the channel of bronchoscope, draw what is extended from the front opening of bronchoscope The electrode catheter 100 that present embodiment is inserted in the lumen of guide sleeve, makes the electrode catheter 100 extended from the front end of guide sleeves Electrode 20 reaches therapentic part as a purpose, in the electrode 20 and attaches in patient body-surface to connecting high frequency between pole plate Electric current burns lung carcinoma cell.

Electrode catheter 100 according to the present embodiment can make electricity according to the bronchial thickness as therapentic part The outer diameter (maximum diameter of basket shape electrode) of pole 20 changes, can be along the bronchial circumferential uniform burn treatment of progress.

In addition, due to constituting electricity by the metal tube M1 (electrode composition part) for being formed with axially extend 16 slits 21 Pole 20, therefore the outer diameter of the electrode 20 when undergauge can be made fully to reduce (as the journey same with the outer diameter of catheter shaft 10 Degree).

It, also can be in bronchiole, alveole thereby, it is possible to make electrode 20 reach the bronchus (bronchiole) of tip The cancer cell of appearance carries out burn treatment.

In addition, carrying out stretched operation to metal tube M1 compressive press forces with cable 60 to operation, thus electrode 20 is along diameter It is deformed into basket shape to expansion, therefore can fully increase the outer diameter (maximum diameter) of electrode 20.

As a result, also can to as main bronchus it is thick it is bronchial around (complete cycle) appearance cancer cell along the branch The circumferential direction of tracheae carries out uniform burn treatment.

In addition, each of 16 protrusions 23 of the electrode 20 of basket shape when composition expansion is by being formed in metal tube The slit 21 of M1 is opened and the tube wall of metal tube M1 (electrode composition part) is made circumferentially to divide and be formed, therefore even if the gold Belong to the component that pipe M1 is thin footpath, can also be reliably formed 16 protrusions 23.

In addition, forming axial slit 21, in metal tube M1 so as to constitute the electrode 20 of basket shape, therefore electrode 20 Be easy to make, the productivity as electrode catheter is excellent.

If here, being for example intended to be made of each of the protrusion of basket shape electrode the pitch tube for being equipped with ring electrode in periphery A, then in the inside of pitch tube configuration conducting wire, core wire etc., therefore the production job of the protrusion becomes cumbersome, and by the tree The outer diameter for the protrusion that rouge pipe is constituted becomes quite thick.

Moreover, even if wanting through such protrusion, the electrode 20 of manufacture and the electrode catheter 100 for constituting present embodiment Same basket shape electrode, is also not by the inside that the pencil body of the base end part of 16 protrusions (pitch tube) is inserted through catheter shaft It is possible.

In addition, if the radical of protrusion to be reduced to the journey that the pencil body of base end part can be inserted into the inside of catheter shaft Spend (can be inserted into the radical inside catheter shaft is several or so at most), then can not using such basket shape electrode along The bronchial circumferential uniform burn treatment of progress.

More than, an embodiment of the invention is illustrated, but it's not limited to that for electrode catheter of the invention, But it is able to carry out various changes.

Such as the quantity of the protrusion of the electrode of composition basket shape is not limited to 16.

In electrode catheter of the invention, the quantity as the protrusion for constituting electrode is (with the slit for being formed in metal tube Quantity it is consistent) be preferably 6 or more, more preferably 8 or more, further preferably 12 or more.

In the case where the quantity of protrusion (slit) is very few, it is difficult to thin to the cancer that (complete cycle) occurs around bronchial Born of the same parents are along the bronchial circumferential uniform burn treatment of progress.

In the case where the quantity of protrusion is few, the configuration gap of bronchial circumferential electrode becomes larger, it is difficult to along this The bronchial circumferential uniform burn treatment of progress.

In addition, the quantity for constituting the temperature sensor of electrode catheter of the invention is not limited to 1, each thermometric portion can also To have circumferentially 2 or 3 or more the temperature sensors that electrode is fixed at equiangularly interval.Alternatively, it is also possible to make Use sensor other than the thermocouple of compensation by thermistor etc. as temperature sensor.

In addition, electrode catheter of the invention is also possible to have the front end for enabling the curved mechanism in the front end portion of catheter shaft The conduit of enough deflecting operations.

Electrode catheter of the invention can also use in the treatment of benign tumor of lung.

< second embodiment >

Structure (the basket of Figure 14 and the lung cancer therapy of the present embodiment shown in figure 15 electrode of electrode catheter 200 Shape) it is different from the electrode catheter of first embodiment.

It in Figure 14 and Figure 15, is identical with first embodiment with the part that symbol identical with Fig. 3~Fig. 5 indicates Structure, and the description thereof will be omitted.

The electrode 70 for constituting the electrode catheter 200 of present embodiment is configured to include: front end side conical portion 701, straight body Cadre 702 and rear end side conical portion 703.

The electrode 70 is axially extended by being fixed on the front end of catheter shaft 10 and being formed in columnar straight trunk 702 The metal tube M2 of 16 slits 71 constitute, when axially compressed, constitute the axial straight line of the tube wall of straight trunk 702 Property be maintained, and slit 71 is opened and radially expands (expanding), and slit 71 is opened to being deformed by the pipe of metal tube M2 Wall is divided and the basket shape of 16 protrusions 73 composition of formation.

16 slits 71 of metal tube M2 are formed in undergauge respectively from the front end of front end side conical portion 701 to rear end The rear end of side conical portion 703 and formed.

16 slits 71 extend in the straight trunk 702 of electrode 70 along axial direction (pipe of metal tube M2 is axial) respectively, preceding End side conical portion 701 is to the inclination of radial direction (caliber of metal tube M2 to) inside and extreme direction extends forward, in rear end side circle Tapered portion 703 is tilted to radially inner side and extreme direction extends backward.

By it is in the tube wall for the metal tube M2 that 16 slits 71 divide and respectively become protrusion 73 in expansion, constitute electricity The tube wall part of the straight trunk 702 of pole 70, though keep metal tube M2 axially compressed and when radially expanding, also with dimension It holds respective linear mode and carries out shape memory.The straight trunk 702 of the electrode 70 of expansion state also has cylinder as a result, Shape.

Such electrode 70 can be by (constituting the metal tube for being formed with axially extend 16 slits in mold The columnar metal tube M1 of the electrode 20 of first embodiment) heated and is formed (to straight trunk and cone The boundary in portion assigns curved trace) and manufacture.

Electrode catheter 200 according to the present embodiment can all play the effect played by first embodiment.

In addition, even if the straight trunk 702 of electrode 70 is also able to maintain that cylindrical shape, therefore makes straight body under expanding state Cadre 702 abuts (face contact) with bronchial inner wall, thus, it is possible to not only along it is bronchial circumferential and also axially into The uniform burn treatment of row.

< third embodiment >

The structure and first embodiment of the lung cancer therapy of present embodiment shown in Figure 16 electrode of electrode catheter 300 Electrode catheter and second embodiment electrode catheter it is different.

It is that (first is real with second embodiment with the part that symbol identical with Figure 14 and Figure 15 indicates in Figure 16 Apply mode) identical structure, and the description thereof will be omitted.

The front end side circular cone of the electrode of the electrode catheter of 300 pairs of electrode catheter composition second embodiments of present embodiment Shape portion (front-end side region 801 for being formed with the part of slit) and rear end side conical portion are (after being formed with the part of slit End side region 803) it is implemented with insulation-coated 85.

As a result, in the electrode catheter of present embodiment 300, front-end side region 801 and rear-end side region 803 not into Row high frequency conduction only (constitutes the electrode of the electrode catheter of second embodiment to the intermediate region 802 for not covering insulation-coated 85 Straight trunk) carry out high frequency conduction, only the intermediate region 802 is functioned as electrode 80.

The electrode catheter 300 of present embodiment can all play the effect played by second embodiment.

In addition, only high frequency conduction is carried out to the intermediate region 802 (straight trunk) contacted with bronchial inner wall, not to not The front-end side region 801 contacted with inner wall and rear-end side region 803 carry out high frequency conduction, therefore are able to suppress high-frequency energy Loss.

Description of symbols: 100 ... electrode catheters；M1 ... metal tube；10 ... catheter shafts；11 ... base end parts；12 ... front ends Portion；13 ... front ends portion；131 ... spiral helicine slits；14 ... resin layers；15 ... central lumens；161~168 ... sub- lumens； 17 ... is internal；18 ... is external；19 ... braided fabrics；20 ... electrodes；21 ... slits；23 ... protrusions；231 ... protrusions；25 ... is preceding Hold blade；30 ... operation handles；31 ... handle main bodies；32 ... grips；33 ... swivel plates；40 ... conducting wires；50 ... temperature sensing Device；55 ... thermometric portions；57 ... collapsible tubes；The resin in the thermometric portion of 58 ... covering temperature sensors；Cable is used in 60 ... operations；61… The front end of cable is used in operation；200 ... electrode catheters；M2 ... metal tube；70 ... electrodes；701 ... front end side conical portions； 702 ... straight trunks；703 ... rear end side conical portions；71 ... slits；73 ... protrusions；300 ... electrode catheters；80 ... electrodes； 801 ... front-end side regions；803 ... rear-end side regions；802 ... intermediate regions；85 ... is insulation-coated.

Claims

1. a kind of lung cancer therapy electrode catheter, which is characterized in that have:

Catheter shaft；

The electrode of high frequency conduction is fixed on the front end of the catheter shaft, by being formed with the multiple slits axially extended Metal tube is constituted, and when axially compressed, the slit is opened and radially expanded, and is deformed into and is made of multiple protrusions Basket shape；

Front end blade is fixed on the front end of the electrode；

Operation handle is fixed on the cardinal extremity of the catheter shaft；

Operation cable, has and is fixed on the front end of the front end blade, can the catheter shaft axially inside Movably extend, cardinal extremity can be stretched operation.

2. lung cancer therapy electrode catheter according to claim 1, which is characterized in that

The metal tube is configured to

Electrode composition part is formed with the slit axially extended；With

Spiral helicine slit or slot are formed in the axis composition part.

3. lung cancer therapy electrode catheter according to claim 1 or 2, which is characterized in that

The catheter shaft has multi-cavity configuration by the position of base end side in the axis composition part than the metal tube.

4. lung cancer therapy electrode catheter described according to claim 1~any one of 3, which is characterized in that

The outer diameter of the catheter shaft is 2.0mm or less.

5. lung cancer therapy electrode catheter described according to claim 1~any one of 4, which is characterized in that

The quantity for being formed in the slit of the metal tube axially extended is 6 or more.

6. lung cancer therapy electrode catheter described according to claim 1~any one of 5, which is characterized in that

Have temperature sensor, there is the thermometric portion for being fixed on the electrode and in the internal stretch of the catheter shaft,

The thermometric portion of the temperature sensor is fixed on described in composition by the collapsible tube for being formed with spiral helicine slit The inner circumferential side of at least 1 protrusion of electrode and it is fixed on the position for being equivalent to the maximum diameter portion of the electrode.

7. lung cancer therapy electrode catheter described according to claim 1~any one of 6, which is characterized in that

The formation of the metal tube has front-end side region and the rear-end side region quilt of the part of the slit axially extended Insulation covering, thus only carries out high frequency conduction to the intermediate region clipped by described two regions.

8. lung cancer therapy electrode catheter according to claim 1, which is characterized in that

The electrode has: front end side conical portion, straight trunk and rear end side conical portion,

The multiple slits for being formed in the metal tube are axially extended in the straight trunk respectively, and in the front end side Conical portion is tilted to radially inner side and extreme direction extends forward, is tilted simultaneously in the rear end side conical portion to radially inner side And extreme direction extends backward,

When the electrode is axially compressed, the electrode is in the axial linearity quilt for constituting the tube wall of the straight trunk It maintains, and the slit is opened and radially expanded, and the basket shape being made of multiple protrusions is deformed into.

9. lung cancer therapy electrode catheter according to claim 8, which is characterized in that

The front end side conical portion and the rear end side conical portion of the metal tube are covered by insulation, thus only to institute It states straight trunk and carries out high frequency conduction.

10. lung cancer therapy electrode catheter described according to claim 1~any one of 9, which is characterized in that

The lung cancer therapy is inserted through in the channel of bronchoscope with electrode catheter to be used.