CN109633504A - A kind of compound magnetic resonance test body mould system of static-dynamic state - Google Patents
A kind of compound magnetic resonance test body mould system of static-dynamic state Download PDFInfo
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- CN109633504A CN109633504A CN201811537152.XA CN201811537152A CN109633504A CN 109633504 A CN109633504 A CN 109633504A CN 201811537152 A CN201811537152 A CN 201811537152A CN 109633504 A CN109633504 A CN 109633504A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/58—Calibration of imaging systems, e.g. using test probes, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material
- G01R33/583—Calibration of signal excitation or detection systems, e.g. for optimal RF excitation power or frequency
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
- G01R33/56308—Characterization of motion or flow; Dynamic imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
- G01R33/56509—Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
Abstract
The invention discloses a kind of static-dynamic compound magnetic resonance of state to test body mould system, including fixing shell, shell seal assembly, static magnetic resonance test module, dynamic magnetic resonance test module, paramagnetism solution I, paramagnetism solution II；Static magnetic resonance test module is solid cube, gets through hole in cross section, arrow section, coronal-plane；Dynamic magnetic resonance test module includes the fast test suite in two channels point, the fast test suite of four-way point, single channel test suite and dynamic shell；The fast test suite in two channels point includes the solid cube in two channels, two channel peripheral assemblies；The fast test suite of four-way point includes four-way hollow cube, four-way peripheral assembly；Single channel test suite includes single channel hollow cube, single channel peripheral assembly；Dynamic shell reserves shell water inlet and shell water outlet.The present invention sufficiently combines dynamic and static quality controling research, and considers high efficiency and accuracy, has the characteristics that low cost, structure is simple, measurement accuracy is high.
Description
Technical field
The present invention relates to magnetic resonance imaging (MRI) systems, and more specifically, it relates to a kind of static-dynamic compound magnetic resonance of state
Test body mould system.
Background technique
With the development of video diagnostic technology, medical nuclear magnetic resonance imaging technology is examined by itself peculiar advantage in medical image
Disconnected field plays a crucial role.MRI machine is capable of providing high-resolution static state in terms of the diagnosis such as soft-tissue imaging
The lesion of fine structure in observer's body may be implemented in image, substantially increases the high efficiency and accuracy of diagnosis.But it is imaged
The quality of quality directly image clinical diagnosis, therefore rest mass control has become the committed step in MRI machine use.
But simple structural images cannot illustrate lesion process, especially blood vessel kind disease well.In view of still image in the cerebrovascular
Limitation in terms of medical diagnosis on disease is also ensured to ensure to provide efficient, high-precision imaging in practical applications for MRI machine, is moved
The control of state quality is also particularly important.But structoure of the human body is complicated, and internal histoorgan contains multiphase like composition, complex-shaped and soft
Property interlaced adjoining, simple static state, Study on dynamic imaging there is certain one-sidedness.Ensure that MRI system is normally transported
Capable and clinical diagnosis validity develops a kind of compound magnetic resonance test of static-dynamic state in conjunction with dynamic and static quality controling research
Body mould system is conducive to comprehensive analysis patient's effective information, also controls the accurate medical diagnosis of human lesion, operation and radiation
Treating planning etc. has important references meaning.
Currently, in terms of static MRI geometric distortion test, International Electrotechnical Commission (IEC), national electrical manufacturers association
(NEMA), United States Medicine physicist association (AAPM) etc. has put into effect relevant criterion, while AAPM and beauty for the control of MRI mass
State's radiation institute (ACR) has developed corresponding MRI test body mould, and the routine quality for MRI controls.But existing body mould design
Majority can only realize the test on a direction, be unable to satisfy three dimension location demand.In terms of Dynamic MRI test, in view of
Limitation of the still image in terms of cerebrovascular disease diagnosis, also to agree with clinical demand at this stage, designing one kind can be to MRI
The dynamic calibration system that physical parameter in imaging is measured, verified, the key step being increasingly becoming in MRI machine use
Suddenly.
Summary of the invention
Purpose of the invention is to overcome the shortcomings in the prior art, meets the control work of MRI clinic routine quality
It needs, sufficiently combines dynamic and static quality controling research, and consider high efficiency and accuracy, propose that one kind is used to test MRI system
Body mould system is tested in the compound magnetic resonance of the static-dynamic state of three-dimensional of system, has the characteristics that low cost, structure is simple, measurement accuracy is high.
The purpose of the present invention is what is be achieved through the following technical solutions.
Body mould system is tested in the compound magnetic resonance of static-dynamic state of the invention, and the fixing shell including cylindrical, hollow is described solid
Determine shell left and right ends mouth and be respectively arranged with shell seal assembly, the fixing shell is internally provided with static magnetic resonance test mould
Block, the static state magnetic resonance test module are internally provided with dynamic magnetic resonance test module, the static state magnetic resonance test module
Inside is filled with paramagnetism solution I, is filled with paramagnetism solution II inside the dynamic magnetic resonance test module；
The static state magnetic resonance test module is set as solid cube structure, and respectively in cross section, arrow section, coronal
Hole is uniformly got through in face, is integrally formed cube static cost control point model；
The dynamic magnetic resonance test module includes two channels point fast test suite, four of successively nested setting from inside to outside
The fast test suite in channel point, single channel test suite and dynamic shell；
The fast test suite in two channel point includes the solid cube in two channels, is set outside the solid cube in two channels
It is equipped with two channel peripheral assemblies；Six surfaces of the solid cube in two channels are uniformly provided with cylindrical hole, and described two
It is semicircular rectangular channel that two sections are opened along Y, Z, X-direction respectively in the upper, left of the solid cube in channel, lower surface, and respectively
It will be the connection of semicircular rectangular channel along the section of Y, Z, X-direction that along X, Y, Y-direction, to open two sections, which be semicircular rectangular channel,
To penetrate through upper, left, lower surface；Two channel peripheral assembly includes six working faces, and each working face offers logical
Hole and transverse and longitudinal groove, wherein trailing face is provided with two channel components water outlets, and top working face is provided with two channel components
Water inlet, right end working face and bottom end working face inner surface offer circulation groove, so as to two channel components water inlets and two-way
Under the solid cube in road, the connection that left, upper surface section is semicircular rectangular channel and two channel components water outlets；
The fast test suite of the four-way point is reserved with four-way component water inlet and four-way component water outlet, and described four
Channel components water outlet is connected with two channel components water inlets；The fast test suite of the four-way point includes that four-way is hollow vertical
Cube is provided with four-way peripheral assembly outside the four-way hollow cube；Six of the four-way hollow cube
Surface is uniformly provided with cylindrical hole, and the upper, left of four-way hollow cube, lower surface are opened along Y, Z, X-direction respectively
Four sections are semicircular rectangular channel, and opening two sections along X, Y, Y-direction respectively is that semicircular rectangular channel will be along Y, Z, X
The section in direction is the connection of semicircular rectangular channel, to penetrate through upper, left, lower surface；The four-way peripheral assembly includes six
Working face, each working face offer through-hole and transverse and longitudinal groove, and the four-way peripheral assembly inner surface offers stream
Through slot, so as under four-way component water inlet and four-way hollow cube, left, upper surface section be semicircular rectangular channel
And the connection of four-way component water outlet；
The single channel test suite is reserved with single channel component water inlet and single channel component water outlet, the single channel
Component water outlet is connected with four-way component water inlet；The single channel test suite includes single channel hollow cube, institute
It states and is provided with single channel peripheral assembly outside single channel hollow cube；Six surfaces of the single channel hollow cube are uniform
Cylindrical hole is offered, it is semicircular rectangular channel that section is opened in the upper, left of single channel hollow cube, lower surface, with
Bow font is uniformly distributed connection, to penetrate through upper, left, lower surface；The single channel peripheral assembly includes six working faces, Mei Gesuo
It states working face and offers through-hole, the single channel peripheral assembly inner surface offers circulation groove, so that single channel component enters water
Mouthful in single channel hollow cube, left, lower surface section be semicircular rectangular channel and single channel component water outlet
Connection；
The dynamic shell uses hollow cubic body case, is reserved with shell water inlet and shell water outlet, the shell
Water inlet is connected with single channel component water inlet, and the shell water outlet is connected with two channel components water outlets.
The fixing shell is internally provided with square through-hole, and the fixing shell bottom is provided with body film support member,
The body film support member bottom is provided with horizontal calibration mechanism, and the fixing shell is provided with spatial scales scale, described solid
Determine shell and body film support member is provided with horizontal alignment bubble.
The fixing shell, shell seal assembly, static magnetic resonance test module and dynamic magnetic resonance test module are adopted
It is made of polymethyl methacrylate.
It is described static state magnetic resonance test module internal liquid using analog biological tissue conductance property, can be in magnetic resonance
The paramagnetism solution I of different T1 and T2 characterisitic parameter numerical value is generated in imaging；The dynamic magnetic resonance test module internal liquid
It is matched using the paramagnetism solution different from static magnetic resonance test module or various concentration, it is special with the T1 and T2 that generate different
Property parameter values.
Compared with prior art, the beneficial effects brought by the technical solution of the present invention are as follows:
The present invention takes into account high efficiency and accuracy to meet MRI clinic routine quality control requirements of one's work.Dynamic is surveyed
Die trial block, when design by the way of nested layer by layer.It is followed successively by single channel, 4 channels, 2 channel dynamic detections from outside to inside, it can
Physical parameter in MRI imaging is measured, is verified, i.e., the dynamic calibration of basic unit on realization three-dimensional space, to be
MRI machine provides precision guarantee, also provides precisely auxiliary foundation for clinical vascular medical diagnosis on disease.Static test module, when design
Based on the testing requirement in three directions, geometric distortion test suite is cube that the aperture of dynamic test module non-active area is constituted
Point model is controlled, accurate space orientation can be carried out, and then complete the test of three-dimensional geometry distortion.Composite test body mould can be right
Physical parameter in MRI imaging is measured, is verified, and is realized three-dimensional distortion correction work, is also provided one for three-dimensional reconstruction
Important reference.It on this basis, can, influencing each other dynamic test module between static with comprehensive analysis, sufficiently excavation
Patient's effective information provides important reference for medical diagnosis on disease and radiotherapy planning etc..
Detailed description of the invention
Fig. 1 is the fast test suite explosive view in two channels point；
Fig. 2 is the fast test suite explosive view of four-way point；
Fig. 3 is single channel test suite explosive view；
Fig. 4 is dynamic shell schematic diagram；
Fig. 5 is static magnetic resonance test module schematic diagram；
Fig. 6 is fixing shell schematic diagram；
Fig. 7 is the compound magnetic resonance test body mould system explosive view of the static-dynamic state of the present invention；
Fig. 8 is the working principle of the invention figure；Wherein, (a) dynamic magnetic resonance test module working principle diagram；
(b) static magnetic resonance test module working principle diagram；(c) composite test body mould working principle diagram.
Appended drawing reference: 1 fixing shell, 2 shell seal assemblies, 3 water inlets, 4 water outlets, 5 body film support members, 6 is horizontal
Correcting mechanism, 7 horizontal alignment bubbles, 8 static magnetic resonance test modules, 901 dynamic shells, the solid cube in 902 2 channels,
903 2 channel peripheral assemblies, 904 2 channel components water outlets, 905 2 channel components water inlets, 906 four-way hollow cubics
Body, 907 four-way peripheral assemblies, 908 four-way component water inlets, 909 four-way component water outlets, 910 single channels are hollow vertical
Cube, 911 single channel peripheral assemblies, 912 single channel component water inlets, 913 single channel component water outlets.
Specific embodiment
The invention will be further described with reference to the accompanying drawing.
The present invention is sufficiently ground in conjunction with the control of dynamic and static quality to meet MRI clinic routine quality control requirements of one's work
Study carefully, and consider high efficiency and accuracy, has developed a kind of compound magnetic resonance test body mould system of static-dynamic state.Dynamic is tested
Module is in design, by the way of nested layer by layer, the relevant informations such as single channel flow velocity on tri- directions outermost layer X, Y, Z
Detect (wherein, patient coordinate: cross section × arrow section × coronal-plane；Space coordinate: X (horizontal axis) × X (longitudinal axis) × Z (vertical pivot),
Similarly hereinafter).Internal layer is followed successively by 4 channels, 2 channels point speed, also achieves the detection of space flow speed etc. in design.Static test mould
Block, the testing requirement based on three directions when design, geometric distortion test suite are cube structure, and the component is in three directions
It constitutes square grid and controls point model, whole then composition cube static cost control point model can carry out accurate space orientation, energy
Enough complete the test of three-dimensional geometry distortion.The static-dynamic compound magnetic resonance test body mould of state can not only join the physics in MRI imaging
Number is measured, is verified, i.e., the dynamic calibration of basic unit on realization three-dimensional space, so that precision guarantee is provided for MRI machine,
Also precisely auxiliary foundation is provided for clinical vascular medical diagnosis on disease；And subsequent three-dimensional distortion correction work may be implemented, for three-dimensional
Reconstruction provides an important reference.It on this basis, can be static with comprehensive analysis, mutual between dynamic test module
It influences, sufficiently excavates patient's effective information, provide important reference for medical diagnosis on disease and radiotherapy planning etc..Due to being certainly
Body mould processed also also effectively controls cost while meeting required precision to a certain extent.
As shown in Figures 1 to 8, body mould system is tested in the compound magnetic resonance of static-dynamic state of the invention, including cylindrical, hollow
Fixing shell 1,1 left and right ends of fixing shell mouthful are respectively arranged with shell seal assembly 2, set inside the fixing shell 1
It is equipped with static magnetic resonance test module 8, the static state magnetic resonance test module 8 is internally provided with dynamic magnetic resonance test module,
It is filled with paramagnetism solution I inside the static state magnetic resonance test module 8, is filled with inside the dynamic magnetic resonance test module
Paramagnetism solution II.
The fixing shell 1 is designed as cylindrical structure, can conveniently be placed in the various radio-frequency coils of MRI, cylindrical body
Inside center is got through with the square body Model for being suitable for size, is formed with square through-hole, so that cylindrical, hollow shell is constituted, with
Just static magnetic resonance test module 8 and dynamic magnetic resonance test module are embedded in.The shell seal assembly 2 is using of corresponding size
Cylindrical body, to close static 8 internal liquid of magnetic resonance test module, the shell seal assembly 2 is provided with water inlet 3 and goes out
The mouth of a river 4.1 bottom of fixing shell is provided with body film support member 5, and 5 bottom of body film support member is provided with horizontal school
Quasi- mechanism 6, the fixing shell 1 are provided with spatial scales scale, and the fixing shell 1 and body film support member 5 are provided with
Horizontal alignment bubble 7.Wherein, horizontal calibration mechanism 6 and horizontal alignment bubble 7 make body mould system of the present invention and body film support portion
When the cooperation of part 5 is placed in magnetic resonance imaging system, user can simply and easily adjust test macro to horizontal position；Space
Graduated scale provides corresponding reference frame for the compound calibration of the static-dynamic state in space.
The fixing shell 1, shell seal assembly 2, static magnetic resonance test module 8 and dynamic magnetic resonance test module etc.
It is all made of polymethyl methacrylate and (PMMA) is made.To meet the needs of user controls MRI machine quality, design specification
Equal test body mould and patient's different parts do not match to carry out the compound calibration of the static-dynamic state of MRI machine.Body mould system of the present invention
Whole laterally maximum external measurement after being placed in body film support member 5 is not more than 250mm, to be adapted to most of MRI scan
The maximum closing coil of system.
8 internal liquid of static state magnetic resonance test module using analog biological tissue conductance property, can be total in magnetic
The paramagnetism solution I of different T1 and T2 characterisitic parameter numerical value is generated in vibration imaging.Liquid inside the dynamic magnetic resonance test module
Body is matched using the paramagnetism solution different from static magnetic resonance test module 8 or various concentration, with generate different T1 and
T2 characterisitic parameter numerical value.
The static state magnetic resonance test module 8 i.e. geometric distortion test suite, is set as solid cube structure, and respectively
Hole is uniformly got through in cross section, arrow section, coronal-plane, is integrally formed cube static cost control point model.The dynamic magnetic resonance is surveyed
Die trial block includes the fast test suite in two channels point, four-way point fast test suite, single channel of successively nested setting from inside to outside
Test suite and dynamic shell 901.
The fast test suite in two channel point includes the solid cube 902 in bis- channel PMMA of a suitable size, described
Two channel peripheral assemblies 903 are provided with outside the solid cube 902 in two channels.Six of the solid cube 902 in two channels
Surface is uniformly provided with cylindrical hole, and solid the upper, left of cube 902 in two channel, lower surface are respectively along Y, Z, X-direction
Open two sections be semicircular rectangular channel, and respectively along X, Y, Y-direction open two sections be semicircular rectangular channel will along Y,
Z, the section of X-direction is the connection of semicircular rectangular channel, to penetrate through upper, left, lower surface.Two channel peripheral assembly 903 wraps
Six working faces are included, each working face offers through-hole and transverse and longitudinal groove, wherein trailing face is provided with two channels
Component water outlet 904 (to be connected to four-way component water outlet 909), top working face is provided with two channel components water inlets
905 (to constitute the water outlet of dynamic magnetic resonance test module), right end working face and bottom end working face inner surface offer
Circulation groove, so as under the solid cube 902 of two channel components water inlets 905 and two channels, left, upper surface section be semicircle
Rectangular channel and two channel components water outlets 904 connection.Correspondingly, in six working faces of two channel peripheral assemblies 903
Upper fluting processing constitutes the fast test suite in two channels point to cooperate to correspond to surface layer manufacturing procedure.
The fast test suite of the four-way point is reserved with four-way component water inlet 908 and four-way component water outlet 909,
The four-way component water outlet 909 is connected with two channel components water inlets 905.The fast test suite of the four-way point includes
The PMMA four-way hollow cube 906 of one appropriate volume, certain thickness (hereinafter referred thickness H), so as to two channels point speed
Test suite is embedded, and is provided with four-way peripheral assembly 907 outside the four-way hollow cube 906.The four-way
Six surfaces of road hollow cube 906 are uniformly provided with cylindrical hole, thick in the H/2 of the fast test suite 907 of four-way point
It is semicircular rectangle that the upper, left of four-way hollow cube 906 of degree, lower surface, which open four sections along Y, Z, X-direction respectively,
Slot, and along X, Y, Y-direction, to open two sections be semicircular rectangular channel to be semicircular square along the section of Y, Z, X-direction respectively
Shape slot connection, to penetrate through upper, left, lower surface.The four-way peripheral assembly 907 includes six working faces, each work
Face offers through-hole and transverse and longitudinal groove, and 907 inner surface of four-way peripheral assembly offers circulation groove, so as to four-way group
Under part water inlet 908 and four-way hollow cube 906, left, upper surface section be semicircular rectangular channel and four-way
The connection of component water outlet 909.Correspondingly, six in four-way peripheral assembly 907 add with a thickness of fluting on the working face of H/2
Work constitutes the fast test suite of four-way point to cooperate to correspond to surface layer manufacturing procedure.
The single channel test suite is reserved with single channel component water inlet 912 and single channel component water outlet 913, described
Single channel component water outlet 913 is connected with four-way component water inlet 908.The single channel test suite includes a thickness
For the PMMA single channel hollow cube 910 of H, so that the fast test suite of four-way point is embedded, the single channel is hollow vertical
Single channel peripheral assembly 911 is provided with outside cube 910.Six surfaces of the single channel hollow cube 910 uniformly open up
There is cylindrical hole, opens section in the upper, left of single channel hollow cube 910 of single channel test suite H/2 thickness, lower surface
For semicircular rectangular channel, it is uniformly distributed connection to bend font, to penetrate through upper, left, lower surface.The single channel peripheral assembly
911 include six working faces, and each working face offers through-hole, and 911 inner surface of single channel peripheral assembly opens up
Have circulation groove, so as in single channel component water inlet 912 and single channel hollow cube 910, left, lower surface section be semicircle
The connection of the rectangular channel and single channel component water outlet 913 of shape.Correspondingly, in six thickness of single channel peripheral assembly 911
Single channel test suite is constituted to cooperate for processing of slotting on the working face of H/2 to correspond to surface layer manufacturing procedure.
The dynamic shell 901 uses hollow cubic body case, is reserved with shell water inlet 914 and shell water outlet 915,
The shell water inlet 914 is connected with single channel component water inlet 912, and the shell water outlet 915 goes out with two channel components
The mouth of a river 904 is connected.
Above-mentioned dynamic magnetic resonance test module and static magnetic resonance test module 8 collectively form composite test body mould, this hair
The infomation detections such as the flow velocity on three-dimensional space may be implemented in phaneroplasm modular system；And cube static cost control point model is constituted, to realize
The functions such as the compound magnetic resonance parameters detection of static-dynamic state, correction.It fills internal liquid respectively inside corresponding module, is embedded in circle
Composite test body mould is finally placed in body film support member 5 by the fixing shell 1 of cylindrical hollow, is put into magnetic resonance imaging use
Excitation/detection coil in, can be tested after integrated regulation to level.Concrete operations are as follows:
(1) dynamic magnetic resonance test module
The physical parameters such as flow rate of liquid, flow, flow direction when the body mould system is by being imaged MRI in body mould carry out
Measurement, verification, can be realized the dynamic calibration of MRI machine.With this parameter measurement of the flow rate of liquid in single channel test suite
For, it is briefly described as follows:
1. defining the flow rate of liquid of Mechanical course in single channel test suite are as follows:
Vx、V-x、Vy、V-y、Vz、V-z
Flow rate of liquid when 2. MRI is imaged in single channel test suite are as follows:
Vx'、V-x'、Vy'、V-y'、Vz'、V-z'
3. will 1. in known Mechanical course flow velocity with 2. in measurement parameter compare, analyze, by evaluating accordingly
(such as normalization root-mean-square error, linearly dependent coefficient), correction index etc., to verify the measurement parameter of magnetic resonance equipment, from
And precision guarantee is provided for MRI machine.
(2) static magnetic resonance test module
1. distorted image pre-processes: distorted image pretreatment mainly includes that adaptive threshold, binary conversion treatment and the spiced salt are made an uproar
Sound denoising.
2. improving the precision of images: carrying out bilinear interpolation processing to pretreated distorted image data, improve image essence
Degree.
3. the determination of control point detection zone: estimating the center of distorted image first, and with the position of estimation for a vertex
And a suitable square area is generated, the mass center in the region is detected, and using this mass center as benchmark, between adjacent control points
It is divided into step-length and determines next detection zone, until determining the plane whole detection zone.
4. control point coordinates determine: in each monitoring area coverage all pixels, determining the center-of-mass coordinate in the region, as
Coordinate when corresponding control point distortion.
Coordinate (x ', y ', z ') when coordinate (x, y, z) and corresponding control point when not being distorted according to control point are distorted, easily
Visually detect the geometric distortion situation of the image on cross section, arrow section, coronal-plane, the i.e. three-dimensional distortion map at control point, control
The three-dimensional distortion of system point is as shown in (1)-(4) formula, wherein i, the control point in three axial directions of distorted image acquired in j, k expression
Number.
dxijk=xijk-xijk (1)
dyijk=yijk-yijk (2)
dzijk=zijk-zijk (3)
Or
After obtaining three-dimensional distortion map, subsequent distortion correction process can be realized by (5) formula.Wherein x, y, z are not to be distorted
When control point coordinate information, x ', y ', the coordinate information at corresponding control point when z ' is distortion, p indicates during distortion correction
Coordinates matrix transformation model.
(3) comprehensive analysis
It compares single in related patents " a kind of Dynamic MRI test body mould system " and " a kind of static state MRI test body mould system "
Only dynamic, static properties test result, analyze the similarities and differences between its important technological parameters and this system, and carry out synthesis and comment
The related works such as valence, calibration and correction preferably realize precisely medical treatment sufficiently to excavate patient's effective information.
Specific embodiment:
The fast test suite in two channel point is 80 × 80 × 80mm3The solid cube of PMMA, volume be 60 × 60
×60mm3Solid the upper, left of cube 902 in two channels, lower surface respectively along Y, Z, X-direction open two length be 20mm,
It is semicircular rectangular channel away from the section for 20mm, and opens along X, Y, Y-direction that two length are 20mm, spacing is 20mm's respectively
Section is that semicircular rectangular channel will be that semicircular rectangular channel is connected to along the section of Y, Z, X-direction.The section is semicircle
Rectangular channel diameter be 5mm, similarly hereinafter.Correspondingly, at six of two channel peripheral assemblies 903 with a thickness of on the working face of 10mm
Fluting processing constitutes the fast test suite in two channels point to cooperate to correspond to surface layer manufacturing procedure.
It is 120 × 120 × 120mm that the fast test suite of the four-way point, which is a volume,3, it is empty with a thickness of the PMMA of 20mm
Body-centred cube.It is 100 × 100 × 100mm in volume3The upper, left of four-way hollow cube 906, lower surface respectively along Y,
Z, X-direction opens that four length are 60mm, the section that spacing is 20mm is semicircular rectangular channel, and opens respectively along X, Y, Y-direction
Two length are 60mm, the section that spacing is 20mm is that semicircular rectangular channel will be semicircular along the section of Y, Z, X-direction
Rectangular channel connection.Correspondingly, six in four-way peripheral assembly 907 are processed with a thickness of fluting on the working face of 10mm, with right
Surface layer manufacturing procedure is answered, constitutes the fast test suite in two channels point to cooperate.
The single channel test suite is that a volume is 160 × 160 × 160mm3, it is hollow vertical with a thickness of the PMMA of 20mm
Cube.It is 140 × 140 × 140mm in volume3The upper, left of single channel hollow cube 910, lower surface open section be semicircle
The rectangular channel of shape is uniformly distributed connection to bend font, to penetrate through upper, left, lower surface.Correspondingly, in single channel peripheral assembly 911
Six with a thickness of processing of slotting on the working face of 10mm, to correspond to surface layer manufacturing procedure, constitute single channel point speed to cooperate
Test suite.
By the fast test suite in two channel point, the fast test suite of four-way point, single channel test suite is nested layer by layer, matches
It closes and forms dynamic magnetic resonance test module.The static state magnetic resonance test module, i.e. geometric distortion test suite is in dynamic magnetic
On the basis of the test module that resonates, gets through hole in cross section, arrow section, coronal-plane respectively and form.Wherein, through-hole diameter 5mm,
Adjacent through-holes spacing is 20mm.
The fixing shell 1 of the cylindrical, hollow is in center with 160 × 160 × 160mm3Square body Model beat
It is logical, square through-hole is formed, to be embedded in static magnetic resonance test module 8 and dynamic magnetic resonance test module.By the static state
Diameter is by magnetic resonance test module 8 and dynamic magnetic resonance test module, the fixing shell of cooperation insertion cylindrical, hollow
240mm, the shell seal assembly 2 of a height of 5mm and fixing shell 1 are placed in body film support member 5 after cooperating, and whole composition is multiple
Close magnetic resonance test body mould.The compound magnetic resonance test body mould is put into excitation/detection coil of magnetic resonance imaging, is adjusted
Whole horizontal calibration mechanism 6 to horizontal alignment bubble 7 is tested when being in a horizontal position (i.e. body mould system is in level).
Although function and the course of work of the invention are described above in conjunction with attached drawing, the invention is not limited to
Above-mentioned concrete function and the course of work, the above mentioned embodiment is only schematical, rather than restrictive, ability
The those of ordinary skill in domain under the inspiration of the present invention, is not departing from present inventive concept and scope of the claimed protection situation
Under, many forms can also be made, all of these belong to the protection of the present invention.
Claims (4)
1. body mould system is tested in a kind of compound magnetic resonance of static-dynamic state, feature is, the fixing shell including cylindrical, hollow
(1), fixing shell (1) left and right ends mouthful are respectively arranged with shell seal assembly (2), are set inside the fixing shell (1)
It is equipped with static magnetic resonance test module (8), the static state magnetic resonance test module (8) is internally provided with dynamic magnetic resonance test mould
Block, is filled with paramagnetism solution I inside static state magnetic resonance test module (8), inside the dynamic magnetic resonance test module
It is filled with paramagnetism solution II；
The static state magnetic resonance test module (8) is set as solid cube structure, and respectively in cross section, arrow section, coronal
Hole is uniformly got through in face, is integrally formed cube static cost control point model；
The dynamic magnetic resonance test module includes two channels point fast test suite, four-way of successively nested setting from inside to outside
Divide fast test suite, single channel test suite and dynamic shell (901)；
The fast test suite in two channel point includes the solid cube in two channels (902), the solid cube in two channels (902)
Outside is provided with two channel peripheral assemblies (903)；Six surfaces of the solid cube in two channels (902) are uniformly provided with circle
Cylindricality through-hole, it is half that two sections are opened along Y, Z, X-direction respectively in the upper, left of the solid cube in two channels (902), lower surface
Circular rectangular channel, and opening two sections along X, Y, Y-direction respectively is that semicircular rectangular channel will be along the section of Y, Z, X-direction
Semicircular rectangular channel connection, to penetrate through upper, left, lower surface；Two channel peripheral assembly (903) includes six working faces,
Each working face offers through-hole and transverse and longitudinal groove, wherein trailing face is provided with two channel components water outlets
(904), top working face is provided with two channel components water inlets (905), and right end working face and bottom end working face inner surface are opened
Equipped with circulation groove, so as under two channel components water inlets (905) and the solid cube in two channels (902), left, upper surface section
For the connection of semicircular rectangular channel and two channel components water outlets (904)；
The fast test suite of the four-way point is reserved with four-way component water inlet (908) and four-way component water outlet (909),
The four-way component water outlet (908) is connected with two channel components water inlets (905)；The fast test suite of the four-way point
Including four-way hollow cube (906), four-way peripheral assembly is provided with outside the four-way hollow cube (906)
(907)；Six surfaces of the four-way hollow cube (906) are uniformly provided with cylindrical hole, and the four-way is hollow
The upper, left of cube (906), lower surface respectively along Y, Z, X-direction open four sections be semicircular rectangular channel, and respectively along X,
Y, it is semicircular rectangular channel that Y-direction, which opens two sections, to be that semicircular rectangular channel is connected to along the section of Y, Z, X-direction, to pass through
Logical upper, left, lower surface；The four-way peripheral assembly (907) includes six working faces, and each working face offers logical
Hole and transverse and longitudinal groove, four-way peripheral assembly (907) inner surface offers circulation groove, so as to four-way component water inlet
(908) with four-way hollow cube (906) under, left, upper surface section be semicircular rectangular channel and four-way component
The connection of water outlet (908)；
The single channel test suite is reserved with single channel component water inlet (912) and single channel component water outlet (913), described
Single channel component water outlet (913) is connected with four-way component water inlet (908)；The single channel test suite includes single-pass
Road hollow cube (910), the single channel hollow cube (910) is external to be provided with single channel peripheral assembly (911)；It is described
Six surfaces of single channel hollow cube (910) are uniformly provided with cylindrical hole, the single channel hollow cube (910)
To open section be semicircular rectangular channel upper, left, lower surface, connection is uniformly distributed to bend font, to penetrate through upper, a left side, lower surface；
The single channel peripheral assembly (911) includes six working faces, and each working face offers through-hole, outside the single channel
It encloses component (911) inner surface and offers circulation groove, so as to single channel component water inlet (912) and single channel hollow cube
(910) on, the connection that left, lower surface section is semicircular rectangular channel and single channel component water outlet (913)；
The dynamic shell (901) uses hollow cubic body case, is reserved with shell water inlet (914) and shell water outlet
(915), the shell water inlet (914) is connected with single channel component water inlet (912), the shell water outlet (915) with
Two channel components water outlets (904) are connected.
2. body mould system is tested in the compound magnetic resonance of static-dynamic state according to claim 1, which is characterized in that outside the fixation
Shell (1) is internally provided with square through-hole, and fixing shell (1) bottom is provided with body film support member (5), the body film branch
Support part part (5) bottom is provided with horizontal calibration mechanism (6), and the fixing shell (1) is provided with spatial scales scale, the fixation
Shell (1) and body film support member (5) are provided with horizontal alignment bubble (7).
3. body mould system is tested in the compound magnetic resonance of static-dynamic state according to claim 1, which is characterized in that outside the fixation
Shell (1), shell seal assembly (2), static magnetic resonance test module (8) and dynamic magnetic resonance test module are all made of poly- methyl-prop
E pioic acid methyl ester is made.
4. body mould system is tested in the compound magnetic resonance of static-dynamic state according to claim 1, which is characterized in that the static-magnetic
Resonance test module (8) internal liquid using analog biological tissue conductance property, difference can be generated in magnetic resonance imaging
The paramagnetism solution I of T1 and T2 characterisitic parameter numerical value；The dynamic magnetic resonance test module internal liquid uses total with static-magnetic
The different paramagnetism solution of test module of shaking or various concentration proportion, to generate different T1 and T2 characterisitic parameter numerical value.
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| CN110448298A (en) * | 2019-07-03 | 2019-11-15 | 清华大学 | Body mould for carotid plaques magnetic resonance imaging |
| CN112951384A (en) * | 2021-02-04 | 2021-06-11 | 慧影医疗科技（北京）有限公司 | Data simulation generation method and system for medical imaging equipment |
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