CN109632653B - Plasma chyle and hemolysis detection device and method based on camera - Google Patents

Plasma chyle and hemolysis detection device and method based on camera Download PDF

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CN109632653B
CN109632653B CN201910062386.1A CN201910062386A CN109632653B CN 109632653 B CN109632653 B CN 109632653B CN 201910062386 A CN201910062386 A CN 201910062386A CN 109632653 B CN109632653 B CN 109632653B
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test tube
plasma
camera
blood
processing system
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CN109632653A (en
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许波
许重远
王超群
陈晓云
梁玉婷
苏清霞
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Southern Hospital Southern Medical University
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Southern Hospital Southern Medical University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation

Abstract

The invention discloses a device and a method for detecting plasma chyle and hemolysis based on a camera, wherein the method comprises the following steps: shooting picture information of blood or plasma in a sample test tube stored in a test tube lattice by a camera; generating a detection result of the chyle degree and the hemolysis degree of the blood plasma through a signal processing system according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor; the motor rotates according to the control signal of the signal processing system, and the rotating amplitude drives the rotating number of turns of the corresponding power wheel; storing the information of the test tubes in the test tube grids, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system by a storage device; and working power supplies are provided for the camera, the storage, the signal processing system and the motor through the power supply. The invention has high accuracy and high practicability, and can be widely applied to the technical field of medical equipment.

Description

Plasma chyle and hemolysis detection device and method based on camera
Technical Field
The invention relates to the technical field of medical equipment, in particular to a device and a method for detecting plasma chyle and hemolysis based on a camera.
Background
In clinical tests, because of overlarge negative pressure during blood collection, violent shaking, large red blood cell fragility of a subject and the like, red blood cells in a collected blood sample are broken to generate hemolytic reaction, and because the components in the red blood cells are different from those in plasma, a large amount of intracellular substances enter the plasma which is light red, so that the accuracy of the clinical blood sample is influenced; when a subject suffers from hyperlipidemia, eats a large amount of fatty foods or is caused by other reasons, a large amount of chylomicrons are contained in plasma to form chylemia, the color of the plasma of the subject is milky, and when the subject suffers from chylemia, the detection of the concentration of a fat-soluble drug is affected, so that the degree of plasma chylemia and the degree of hemolysis of a recorded sample need to be observed after a blood sample is centrifuged.
In the process of collecting blood samples, different subjects may use test tubes with different specifications for collection, and the blood volume collected in different clinical tests is not necessarily the same, so the blood liquid level height collected in each collection test tube is not uniform, it is obviously impractical to use a fixed-height device to obtain the blood conditions in the test tubes with different specifications, the existing method generally distinguishes the hemolysis degree and the chyle degree by observing the color of plasma with naked eyes by medical staff, and the error rate of the method of artificial subjective judgment is high.
Disclosure of Invention
To solve the above technical problems, the present invention aims to: the device and the method for detecting plasma chyle and hemolysis based on the camera are high in practicability and accuracy.
On one hand, the technical scheme adopted by the invention is as follows:
the plasma chyle and hemolysis detection device based on the camera comprises a base, wherein a signal processing system, a power supply, a motor and a storage device are arranged in the base, a plurality of test tube lattices are arranged on the base, hard plastic shells are arranged on the test tube lattices, the camera is arranged on the side wall or the rear wall of each hard plastic shell, a fixing force wheel is arranged above the camera, a power wheel is arranged below the camera, the fixing force wheel and the power wheel are connected through double chains, the camera is positioned between the double chains, and an output shaft of the motor is connected with the power wheel;
the camera is used for shooting picture information of blood or blood plasma in a sample test tube stored in the test tube lattice;
the signal processing system is used for generating a detection result of the chyle degree and the hemolysis degree of the blood plasma according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor is used for rotating according to the control signal of the signal processing system, and the rotating amplitude drives the rotating turns of the corresponding power wheel;
the storage device is used for storing the information of the test tubes in the test tube lattices, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system;
and the power supply is used for providing working power supply for the camera, the storage, the signal processing system and the motor.
Furthermore, an RFID chip reader is also arranged on the test tube lattice;
the RFID chip reader is used for acquiring the RFID chip data of the blood sample test tube in the test tube lattice in real time.
Further, a yellow light lamp is arranged at the bottom of the test tube lattice;
the yellow light lamp is used for emitting yellow light to illuminate the sample test tube in the test tube lattice according to a control signal of the signal processing system so as to prevent the medicine or metabolite in the blood plasma from being decomposed in natural light.
Further, a side wall distance sensor is arranged on one side of the inner side wall of the hard plastic shell, and a bottom distance sensor is arranged at the bottom of the hard plastic shell;
the side wall distance sensor is used for measuring the distance between the side wall of the inner side of the rigid plastic shell and the side wall of the test tube;
and the bottom distance sensor is used for measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube.
The technical scheme adopted by the other aspect of the invention is as follows:
a plasma chyle and hemolysis detection method based on a camera comprises the following steps:
shooting picture information of blood or plasma in a sample test tube stored in a test tube lattice by a camera;
generating a detection result of the chyle degree and the hemolysis degree of the blood plasma through a signal processing system according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor rotates according to the control signal of the signal processing system, and the rotating amplitude drives the rotating number of turns of the corresponding power wheel;
storing the information of the test tubes in the test tube grids, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system by a storage device;
and working power supplies are provided for the camera, the storage, the signal processing system and the motor through the power supply.
Further, the method also comprises the following steps:
acquiring RFID chip data of the blood sample test tube in the test tube lattice in real time through an RFID chip reader;
and according to the control signal of the signal processing system, the yellow light is emitted by the yellow light lamp to illuminate the sample test tube in the test tube lattice.
Further, the method also comprises the following steps:
measuring the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube by using a side wall distance sensor;
and measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube by using a bottom distance sensor.
Further, the method also comprises the following steps:
scanning the shot picture information based on the area proportion relation of the blood cell area, the plasma area and the blank area in the same picture, and identifying to obtain a picture of the plasma area;
and matching and comparing the picture of the identified plasma area with a pre-stored standard picture to obtain the detection results of the chyle degree and the hemolysis degree of the plasma to be detected.
Further, the method also comprises the following steps:
calculating the mass of the blood;
calculating the volume of blood based on the mass of blood;
calculating the liquid level area in the test tube according to the diameter of the hard plastic shell and the distance between the inner side wall of the hard plastic shell and the side wall of the test tube;
calculating the height of the blood in the test tube according to the volume of the blood and the liquid level area;
the empty tube height in the tube is calculated based on the tube size and the height of the blood in the tube.
The invention has the beneficial effects that: the invention is additionally provided with the camera, can obtain the color picture of the plasma in the test tube in real time, and is matched with the signal processing system and the storage to obtain the detection results of plasma chyle and hemolysis, so that the accuracy is high; in addition, the motor starts to work according to a control signal of the signal processing system, so that the power wheel is driven to rotate, the height position of the camera is adjusted by matching the fixing force wheel and the double chains, blood samples of test tubes of different specifications can be detected, and the practicability is high.
Drawings
FIG. 1 is a block diagram of the overall functional modules of an embodiment of the present invention;
FIG. 2 is a schematic overall structure diagram of an embodiment of the present invention;
FIG. 3 is a schematic diagram of the connection of a fixed force wheel and a power wheel according to an embodiment of the invention.
Detailed Description
The invention will be further explained and explained with reference to the drawings and the embodiments in the description.
The embodiment of the invention provides a plasma chyle and hemolysis detection device based on a camera, which comprises a base, wherein a signal processing system, a power supply, a motor and a storage device are arranged in the base, a plurality of test tube lattices are arranged on the base, hard plastic shells are arranged on the test tube lattices, the camera is arranged on the side wall or the rear wall of each hard plastic shell, a fixing force wheel is arranged above the camera, a power wheel is arranged below the camera, the fixing force wheel and the power wheel are connected through double chains, the camera is positioned between the double chains, and an output shaft of the motor is connected with the power wheel;
the camera is used for shooting picture information of blood or blood plasma in a sample test tube stored in the test tube lattice;
the signal processing system is used for generating a detection result of the chyle degree and the hemolysis degree of the blood plasma according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor is used for rotating according to the control signal of the signal processing system, and the rotating amplitude drives the rotating turns of the corresponding power wheel;
the storage device is used for storing the information of the test tubes in the test tube lattices, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system;
and the power supply is used for providing working power supply for the camera, the storage, the signal processing system and the motor.
Further as a preferred embodiment, an RFID chip reader is further disposed on the test tube lattice;
the RFID chip reader is used for acquiring the RFID chip data of the blood sample test tube in the test tube lattice in real time.
Further as a preferred embodiment, the bottom of the test tube lattice is provided with a yellow light lamp;
the yellow light lamp is used for emitting yellow light to illuminate the sample test tube in the test tube lattice according to a control signal of the signal processing system so as to prevent the medicine or metabolite in the blood plasma from being decomposed in natural light.
Further as a preferred embodiment, a side wall distance sensor is arranged on one side of the inner side wall of the hard plastic shell, and a bottom distance sensor is arranged at the bottom of the hard plastic shell;
the side wall distance sensor is used for measuring the distance between the side wall of the inner side of the rigid plastic shell and the side wall of the test tube;
and the bottom distance sensor is used for measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube.
Based on the device shown in fig. 1, the embodiment of the invention also provides a plasma chyle and hemolysis detection method based on a camera, which comprises the following steps:
shooting picture information of blood or plasma in a sample test tube stored in a test tube lattice by a camera;
generating a detection result of the chyle degree and the hemolysis degree of the blood plasma through a signal processing system according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor rotates according to the control signal of the signal processing system, and the rotating amplitude drives the rotating number of turns of the corresponding power wheel;
storing the information of the test tubes in the test tube grids, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system by a storage device;
and working power supplies are provided for the camera, the storage, the signal processing system and the motor through the power supply.
Further as a preferred embodiment, the method further comprises the following steps:
acquiring RFID chip data of the blood sample test tube in the test tube lattice in real time through an RFID chip reader;
and according to the control signal of the signal processing system, the yellow light is emitted by the yellow light lamp to illuminate the sample test tube in the test tube lattice.
Further as a preferred embodiment, the method further comprises the following steps:
measuring the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube by using a side wall distance sensor;
and measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube by using a bottom distance sensor.
Further as a preferred embodiment, the method further comprises the following steps:
scanning the shot picture information based on the area proportion relation of the blood cell area, the plasma area and the blank area in the same picture, and identifying to obtain a picture of the plasma area;
and matching and comparing the picture of the identified plasma area with a pre-stored standard picture to obtain the detection results of the chyle degree and the hemolysis degree of the plasma to be detected.
Further as a preferred embodiment, the method further comprises the following steps:
calculating the mass of the blood;
calculating the volume of blood based on the mass of blood;
calculating the liquid level area in the test tube according to the diameter of the hard plastic shell and the distance between the inner side wall of the hard plastic shell and the side wall of the test tube;
calculating the height of the blood in the test tube according to the volume of the blood and the liquid level area;
the empty tube height in the tube is calculated based on the tube size and the height of the blood in the tube.
The following describes in detail the specific working principle of a camera-based plasma chyle and hemolysis detection device according to the present invention with reference to the attached drawings:
as shown in fig. 2, the camera 1.4 is located on the side wall or the rear wall of the rigid plastic shell;
a side wall distance sensor 1.6 is additionally arranged above the left side or the right side or the front side and the rear side of the inner side wall of the rigid plastic shell 1.1 and is used for measuring the distance between the inner side wall of the rigid plastic shell 1.1 and the side wall of the test tube; the camera is positioned below the side wall distance sensor 1.6;
a bottom distance sensor 1.7 is added in the right middle of the bottom of the inner side of the rigid plastic shell and is used for measuring the distance between the bottom of the inner side of the rigid plastic shell and the bottom of the test tube;
when the sidewall distance sensor 1.6 and the bottom distance sensor 1.7 sense that the test tube is inserted, the camera scans the test tube, and stores the scanned test tube in the form of a picture, and finally obtains the picture of the whole test tube after centrifugation.
According to the invention, the storage device is used for storing pictures corresponding to different plasma chyle degrees and plasma hemolysis degrees, after the camera acquires the actual picture, the signal processing system compares the actual picture with the picture stored in the storage device through the prior art to obtain the plasma chyle degree and the plasma hemolysis degree corresponding to the plasma in the actual test tube.
A fixed force wheel 1.8 and a power wheel 1.9 are arranged above the side wall or the rear wall of the hard plastic shell;
as shown in figure 3, the fixed force wheel 1.8 is connected with the power wheel 1.9 through double chains, the camera 1.4 is positioned between the double chains, and the movement of the double chains can drive the camera 1.4 to move up and down on the hard plastic shell.
And a side wall distance sensor 1.6 is additionally arranged on the left side or the right side or the front side and the rear side of the inner side wall of the hard plastic shell and used for measuring the distance between the inner side wall of the hard plastic shell and the side wall of the test tube.
And a bottom distance sensor 1.7 is added in the right middle of the bottom of the inner side of the rigid plastic shell and is used for measuring the distance between the bottom of the inner side of the rigid plastic shell and the bottom of the test tube.
Because the same collection test tube but the different blood volumes of taking a blood sample or use the test tube height when gathering the sample inequality, it is unsettled to lead to plasma in the test tube for the position of test tube check after the centrifugation, therefore camera 1.4 need constantly adjust the height in the test tube check, just can effectively shoot the color picture of plasma in the test tube. The invention can automatically adjust the height of the camera 1.4 according to the test tube after being placed in the centrifuge, and has high practicability.
In addition, as shown in fig. 2, the detection device of the present invention comprises a test tube 1, a signal processing system 2, a base 3, a power source 4, a reservoir 5, a blood sample test tube 6, and a display 7; test tube lattice 1 be adiactinic top open-ended cuboid structure, blood sample test tube 6 after each test tube lattice 1 placed a centrifugation, test tube lattice 1 be used for responding to the blood sample test tube 6's after the centrifugation information and give signal processing system 2 with information transmission, base 3 can settle a plurality of test tube lattices 1, signal processing system 2 be arranged in receiving gravity inductor 1.2, RFID chip reader 1.3 and camera 1.4's signal and will handle the back information transmission to display 7, power 4 be used for providing electric power for signal processing system 2, gravity inductor 1.2, camera 1.4, RFID chip reader 1.3, yellow-light lamp 1.5 and display 7.
Preferably, the test tube lattice 1 consists of a hard plastic shell 1.1, a gravity sensor 1.2, a camera 1.4, an RFID chip reader 1.3 and a yellow light lamp 1.5, wherein the hard plastic shell 1.1 is a cuboid with an opening at the upper end, and the opening at the upper end of the hard plastic shell 1.1 is circular; the diameter of the opening at the upper end of the hard plastic shell 1.1 is larger than the diameter of the centrifuged blood sample test tube 6 and smaller than the diameter of the centrifuged blood sample test tube 6 cap.
Hard plastic shell 1.1 upper end opening inner wall pass through the 6 wall contacts of blood sample test tube after elastic material and centrifugation, blood sample test tube 6 after both accessible elastic material fixes the centrifugation can avoid outside light source to get into again and influence camera 1.4 in the test tube check 1 and shoot the result, the optional black silica gel of using of elastic material, the opening of silica gel slightly is less than the external diameter of test tube.
Gravity inductor 1.2 be located stereoplasm plastic shell 1.1 upper end for whether there is gravity above the response test tube check 1, and send gravity signal to signal processing system 2. When gravity exists on the test tube lattice 1, the test tube lattice 1 is inserted with the centrifuged blood sample test tube 6, and when no gravity exists above the test tube lattice 1, the test tube lattice 1 is not inserted with the centrifuged blood sample test tube 6.
The RFID chip reader 1.3 is located on the left side of the rigid plastic shell 1.1, and after the test tube lattice 1 is inserted into the centrifuged blood sample test tube 6, the RFID chip reader 1.3 reads information of a built-in RFID chip label on the centrifuged blood sample test tube 6 and sends the information to the signal processing system 2.
The camera 1.4 is located on the inner wall of the front side of the rigid plastic shell 1.1, and the camera 1.4 is used for shooting images of the color of blood plasma in the centrifuged blood sample test tube 6 and sending information to the signal processing system 2.
The yellow light lamp 1.5 is located at the bottom of the inner side of the hard plastic shell 1.1, and the yellow light lamp 1.5 is used for providing a light source for the camera 1.4.
The signal processing system 2 is positioned in the base 3, the signal processing system 2 is used for receiving the information of the gravity sensor 1.2, the camera 1.4 and the RFID chip reader 1.3 and sending the processed information to the display 7, when the gravity sensor 1.2 senses that a gravity signal exists above the test tube lattice 1, the signal processing system 2 sends a signal to the RFID chip reader 1.3, the RFID chip reader 1.3 reads information of a built-in RFID chip label on the centrifuged blood sample test tube 6 and sends the read information to the signal processing system 2, the signal processing system 2 sends the read information to the display 7, meanwhile, the signal processing system 2 sends signals to the camera 1.4 and the yellow light lamp 1.5, the yellow light lamp 1.5 is turned on, the camera 1.4 shoots the color image of the blood plasma and sends the image to the signal processing system 2, the signal processing system 2 obtains the chyle degree and the hemolysis degree of the detected plasma and sends the result to the display 7.
The power supply 4 is positioned in the base 3, and the power supply 4 is used for providing power for the signal processing system 2, the gravity sensor 1.2, the camera 1.4, the RFID chip reader 1.3, the yellow light lamp 1.5 and the display 7.
The storage device 5 is located in the base 3 and used for storing test tube information and the chyle degree and the hemolysis degree of plasma in the test tube.
The display 7 is positioned in front of the upper end of the test tube lattice 1 and is used for displaying the information of the centrifuged blood sample test tube 6 sent by the signal processing system 2 and the chyle degree and the hemolysis degree of the plasma.
The display 7 is positioned in front of the upper end of the test tube lattice 1 and is used for displaying the test tube information of the centrifuged blood sample and the chyle degree and the hemolysis degree of the plasma sent by the signal processing system 2.
The specific implementation steps of the detection method of plasma chyle and hemolysis based on the camera are described in detail as follows:
s1, calculating the quality of blood;
first, an empty test tube for blood collection is set in the device of the present invention, and a gravity sensor in the device reads the gravity W of the empty test tube1
Then, the centrifuged tube is placed in the apparatus, and the gravity sensor in the apparatus reads the gravity W of the centrifuged tube2Then, the gravity Δ W (W) of the change before and after the calculation is calculated2-W1);
Finally, the mass of the blood collected in the test tube is calculated
Figure BDA0001954562830000071
Wherein g is 9.8N/KG.
S2, calculating the volume of the blood;
according to the formula of density
Figure BDA0001954562830000072
To calculate the volume of blood
Figure BDA0001954562830000073
Wherein the relative density of blood to water is 1.05-1.06, and in the calculation process of the embodiment, the average relative density of 1.055 is selected as the blood density, and the volume of blood is calculated to be
Figure BDA0001954562830000074
S3, calculating the diameter and the inserted length of the test tube;
side wall distance sensor for measuring diameter d of hard plastic shell1And the distance L between the rigid plastic shell and the test tube wall1. Diameter d of outer side wall of test tube2=d1-2×L1Thus the inside diameter d of the test tube3=d2-2L2Wherein L is2For the thickness of the blood sampling test tube, the value in the embodiment is 1 mm, the area in the test tube is obtained by calculation
Figure BDA0001954562830000081
Measuring the height H of a rigid plastic housing by means of a bottom distance sensor1And after the test tube is inserted into the test tube lattice, the distance L between the bottom of the test tube lattice and the hard plastic shell3Thus, for the inserted test tube length L2Which is equal to the height H of the rigid plastic shell1At the distance L3The difference between, i.e.: l is2=H1-L3
Because a fixed distance L exists between the camera and the opening at the upper end of the hard plastic shell4Thus for the tube length L obtained by scanning5Equal to the length L of the inserted test tube2At the distance L4The difference between, i.e.: l is5=L2-L4
S4, calculating the height H of the blood in the test tube1
The height of the collected blood in the test tube is
Figure BDA0001954562830000082
Because the blood in human body mainly consists of plasma and blood cells, the volume percentage of the blood cells in the blood is called hematocrit, the hematocrit of a normal adult male is 40% -50%, the hematocrit of a normal adult female is 37% -48%, and the height of the blood cells in a test tube after centrifugation is about equal to that of the blood cells in the test tube after centrifugation
Figure BDA0001954562830000083
The height of the plasma is
Figure BDA0001954562830000084
S5, calculating the height H of the tube hollow tube scanned2
Scanning to the height H of the hollow tube of the test tube2Equal to the length L of the scanned test tube5Height H of blood in test tube1The difference between, i.e.: h2=L5-H1
S6, scanning the proportion of a blood cell area, a plasma area and a blank area in a picture;
the proportion of the blood cell area in the picture in the whole picture is
Figure BDA0001954562830000085
The ratio of the plasma region to the whole picture is
Figure BDA0001954562830000086
The proportion of the blank area in the whole picture is
Figure BDA0001954562830000087
In the picture, the lowest layer is blood cells, the middle layer is blood plasma, and the uppermost layer is a hollow tube area, so the picture is divided into a plurality of equal parts according to the distribution ratio of the three areas, the area of the blood plasma is found according to the proportion, and the picture corresponding to the blood plasma is obtained by screenshot.
In summary, the invention has the following advantages:
1. the camera can shoot a high-definition image of plasma, so that a signal processing system can obtain objective detection results of plasma chyle degree and hemolysis degree, particularly when the collected blood sample has chyle blood and hemolysis at the same time, the conditions that the standard is not uniform and the judgment result is not uniform due to subjective factors of an operator can be avoided, and the chyle degree and the hemolysis degree of the plasma in the test tube can be timely and accurately reflected through the picture shot by the camera;
2. the whole test tube lattice is sealed and light-proof, natural light cannot enter the test tube lattice, and meanwhile, the yellow light provides a light source for the camera, so that the medicine or metabolite in blood plasma can be effectively prevented from being decomposed under the natural light, detection errors are avoided, and the quality of a sample is improved;
3. the motor starts to work according to the control signal of the signal processing system, so that the power wheel is driven to rotate, the height position of the camera is adjusted by matching the fixing force wheel and the double chains, blood samples of test tubes with different specifications can be detected, and the motor is wide in application range and high in practicability.
4. According to the invention, the distance between the rigid plastic shell and the test tube is sensed in real time through the side wall distance sensor and the bottom distance sensor, the signal processing system triggers corresponding control signals according to the sensed distance signals to control the work of the modules such as the motor and the display, so that collision between the test tube and the rigid plastic shell due to the close distance can be prevented, and the safety is high.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (5)

1. Plasma chyle and hemolysis detection device based on camera, its characterized in that: the test tube test device comprises a base, wherein a signal processing system, a power supply, a motor and a storage device are arranged in the base, a plurality of test tube lattices are arranged on the base, hard plastic shells are arranged on the test tube lattices, cameras are arranged on the side walls or the rear walls of the hard plastic shells, a fixing force wheel is arranged above the cameras, a power wheel is arranged below the cameras, the fixing force wheel and the power wheel are connected through double chains, the cameras are positioned between the double chains, and an output shaft of the motor is connected with the power wheel;
the camera is used for shooting picture information of blood or blood plasma in a sample test tube stored in the test tube lattice;
the signal processing system is used for comparing the picture shot by the camera with the picture stored in the memory to generate a detection result of the chyle degree and the hemolysis degree of the blood plasma; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor is used for rotating according to the control signal of the signal processing system, and the rotating amplitude drives the rotating turns of the corresponding power wheel;
the storage device is used for storing information of test tubes in the test tube grids, pictures corresponding to different plasma chyle degrees and plasma hemolysis degrees, detection results of the chyle degrees and the hemolysis degrees of the plasma in the test tubes and control signals of the signal processing system;
the power supply is used for providing a working power supply for the camera, the storage, the signal processing system and the motor;
the test tube lattice is of a light-tight cuboid structure with an opening at the upper part;
a yellow light lamp is arranged at the bottom of the test tube lattice;
the yellow light lamp is used for emitting yellow light to illuminate the sample test tube in the test tube lattice according to a control signal of the signal processing system so as to prevent the medicine or metabolite in the blood plasma from being decomposed in natural light;
a side wall distance sensor is arranged on one side of the inner side wall of the hard plastic shell, and a bottom distance sensor is arranged at the bottom of the hard plastic shell;
the side wall distance sensor is used for measuring the distance between the side wall of the inner side of the rigid plastic shell and the side wall of the test tube; and the bottom distance sensor is used for measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube.
2. The camera-based plasma chyle and hemolysis detection device of claim 1, wherein: the test tube grids are also provided with RFID chip readers;
the RFID chip reader is used for acquiring the RFID chip data of the blood sample test tube in the test tube lattice in real time.
3. Plasma chyle and hemolysis detection method based on camera, which is characterized in that: applied to the camera-based plasma chyle and hemolysis detection device of claim 2, the method comprising the steps of:
shooting picture information of blood or plasma in a sample test tube stored in a test tube lattice by a camera;
generating a detection result of the chyle degree and the hemolysis degree of the blood plasma through a signal processing system according to the picture shot by the camera; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor rotates according to the control signal of the signal processing system, and the rotating amplitude drives the rotating number of turns of the corresponding power wheel;
storing the information of the test tubes in the test tube grids, the detection results of the chyle degree and the hemolysis degree of the plasma in the test tubes and the control signals of the signal processing system by a storage device;
working power supplies are provided for the camera, the storage, the signal processing system and the motor through a power supply;
measuring the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube by using a side wall distance sensor;
measuring the distance between the bottom of the inner side of the rigid plastic shell and the bottom of the test tube by a bottom distance sensor;
scanning the shot picture information based on the area proportion relation of the blood cell area, the plasma area and the blank area in the same picture, and identifying to obtain a picture of the plasma area;
and matching and comparing the picture of the identified plasma area with a pre-stored standard picture to obtain the detection results of the chyle degree and the hemolysis degree of the plasma to be detected.
4. The camera-based plasma chyle and hemolysis detection method of claim 3, wherein: further comprising the steps of:
acquiring RFID chip data of the blood sample test tube in the test tube lattice in real time through an RFID chip reader;
and according to the control signal of the signal processing system, the yellow light is emitted by the yellow light lamp to illuminate the sample test tube in the test tube lattice.
5. The camera-based plasma chyle and hemolysis detection method of claim 4, wherein: further comprising the steps of:
calculating the mass of the blood;
calculating the volume of blood based on the mass of blood;
calculating the liquid level area in the test tube according to the diameter of the hard plastic shell and the distance between the inner side wall of the hard plastic shell and the side wall of the test tube;
calculating the height of the blood in the test tube according to the volume of the blood and the liquid level area;
the empty tube height in the tube is calculated based on the tube size and the height of the blood in the tube.
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CN111829962B (en) * 2020-06-28 2023-03-28 中国科学院苏州生物医学工程技术研究所 Plasma chyle degree detection method and system
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101581676A (en) * 2008-05-14 2009-11-18 基立福有限公司 Microtube reader device for the analysis of blood samples
CN201945596U (en) * 2010-11-24 2011-08-24 广东紫金正天药业有限公司 Blood clots detector
CN204286545U (en) * 2014-12-08 2015-04-22 重庆南方数控设备有限责任公司 Blood plasma extraction equipment
CN105637370A (en) * 2013-11-12 2016-06-01 株式会社日立高新技术 Analyte testing automation system, biological sample check module, and biological sample check method
CN205562387U (en) * 2016-05-03 2016-09-07 青岛市中心血站 Plasma chyle degree dynamic verification device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101581676A (en) * 2008-05-14 2009-11-18 基立福有限公司 Microtube reader device for the analysis of blood samples
CN201945596U (en) * 2010-11-24 2011-08-24 广东紫金正天药业有限公司 Blood clots detector
CN105637370A (en) * 2013-11-12 2016-06-01 株式会社日立高新技术 Analyte testing automation system, biological sample check module, and biological sample check method
CN204286545U (en) * 2014-12-08 2015-04-22 重庆南方数控设备有限责任公司 Blood plasma extraction equipment
CN205562387U (en) * 2016-05-03 2016-09-07 青岛市中心血站 Plasma chyle degree dynamic verification device

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