CN109632652B - Device and method for detecting plasma chyle and hemolysis suitable for test tubes of multiple specifications - Google Patents

Device and method for detecting plasma chyle and hemolysis suitable for test tubes of multiple specifications Download PDF

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CN109632652B
CN109632652B CN201910062385.7A CN201910062385A CN109632652B CN 109632652 B CN109632652 B CN 109632652B CN 201910062385 A CN201910062385 A CN 201910062385A CN 109632652 B CN109632652 B CN 109632652B
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test tube
color sensor
plastic shell
distance
plasma
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CN109632652A (en
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许波
陈晓云
许重远
王超群
彭朋
梁玉婷
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Nanfang Hospital of Southern Medical University
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Nanfang Hospital of Southern Medical University
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Abstract

本发明公开了适用于多规格试管的血浆乳糜和溶血的检测装置及方法,方法包括:通过颜色感应器实时获取放置在试管格中试管内血液样本的颜色感应信号;根据血液颜色感应信号,通过信号处理系统触发相应的控制信号,并将控制信号发送至电动机;电动机根据信号处理系统的控制信号转动相应幅度,进而带动动力轮转动相应的圈数,以实现对颜色感应器的高度位置调整;通过电源为信号处理系统、电动机和颜色感应器提供工作电源信号。本发明的检测结果准确率高且实用性高,可广泛应用于医疗设备技术领域。

Figure 201910062385

The invention discloses a detection device and method for plasma chyle and hemolysis suitable for multi-specification test tubes. The method includes: real-time acquisition of color sensing signals of blood samples in test tubes placed in test tube grids through a color sensor; The signal processing system triggers the corresponding control signal and sends the control signal to the motor; the motor rotates the corresponding amplitude according to the control signal of the signal processing system, and then drives the power wheel to rotate the corresponding number of turns to realize the height position adjustment of the color sensor; Provides operating power signals for signal processing systems, motors and color sensors through the power supply. The detection result of the invention has high accuracy and high practicability, and can be widely used in the technical field of medical equipment.

Figure 201910062385

Description

Device and method for detecting plasma chyle and hemolysis suitable for test tubes of multiple specifications
Technical Field
The invention relates to the technical field of medical equipment, in particular to a device and a method for detecting plasma chyle and hemolysis of a multi-specification test tube.
Background
In clinical tests, because of overlarge negative pressure during blood collection, violent shaking, large red blood cell fragility of a subject and the like, red blood cells in a collected blood sample are broken to generate hemolytic reaction, and because the components in the red blood cells are different from those in plasma, a large amount of intracellular substances enter the plasma which is light red, so that the accuracy of the clinical blood sample is influenced; when a subject suffers from hyperlipidemia, eats a large amount of fatty foods or is caused by other reasons, a large amount of chylomicrons are contained in plasma to form chylemia, the color of the plasma of the subject is milky, and when the subject suffers from chylemia, the detection of the concentration of a fat-soluble drug is affected, so that the degree of plasma chylemia and the degree of hemolysis of a recorded sample need to be observed after a blood sample is centrifuged.
In the process of collecting blood samples, different subjects may use test tubes of different specifications to collect blood samples, and the amount of blood collected by detection items is not necessarily the same, so the blood liquid level height collected in each collection test tube is not uniform, it is obviously impractical to use a device with a fixed height to obtain the blood conditions in test tubes of different specifications, the existing method generally distinguishes the degree of hemolysis and chyle by observing the color of plasma with naked eyes by medical personnel, and the error rate of the method of artificial subjective judgment is high.
Disclosure of Invention
To solve the above technical problems, the present invention aims to: the device and the method for detecting plasma chyle and hemolysis are high in practicability and accuracy and suitable for test tubes of multiple specifications.
On one hand, the technical scheme adopted by the invention is as follows:
the detection device is suitable for plasma chyle and hemolysis of test tubes of various specifications and comprises a base, wherein a signal processing system, a power supply and a motor are arranged in the base, a plurality of test tube lattices are arranged on the base, hard plastic shells are arranged on the test tube lattices, a color sensor is arranged on the side wall or the rear wall of each hard plastic shell, a fixing force wheel is arranged above the color sensor, a power wheel is arranged below the color sensor, the fixing force wheel is connected with the power wheel through double chains, and the color sensor is positioned between the double chains;
the color sensor is used for acquiring color sensing signals of a blood sample in a test tube placed in the test tube lattice in real time;
the signal processing system is used for generating a detection result of the chyle degree and the hemolysis degree of the plasma according to the blood color sensing signal; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor is used for rotating by a corresponding amplitude according to a control signal of the signal processing system so as to drive the power wheel to rotate by a corresponding number of turns, so that the height position of the color sensor is adjusted;
and the power supply is used for providing working power supply signals for the signal processing system, the motor and the color sensor.
Further, a side wall distance sensor is arranged on one side of the inner side wall of the hard plastic shell;
the side wall distance sensor is used for measuring the distance between the side wall of the inner side of the rigid plastic shell and the side wall of the test tube.
Further, a bottom distance sensor is arranged at the bottom of the hard plastic shell;
the bottom distance sensor is used for measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube.
Furthermore, a gravity sensor is also arranged on the hard plastic shell;
wherein, the gravity inductor is used for acquiring the gravity signal of the test tube in the test tube lattice in real time.
The technical scheme adopted by the other aspect of the invention is as follows:
the method of the plasma chyle and hemolysis detection device suitable for the multi-specification test tubes comprises the following steps:
acquiring a color sensing signal of a blood sample in a test tube placed in a test tube lattice in real time through a color sensor;
triggering a corresponding control signal through a signal processing system according to the blood color sensing signal, and sending the control signal to the motor;
the motor rotates by a corresponding amplitude according to a control signal of the signal processing system, and then drives the power wheel to rotate by a corresponding number of turns so as to realize the height position adjustment of the color sensor;
the signal processing system, the motor and the color sensor are provided with working power supply signals through a power supply.
Further, the method also comprises the following steps:
and measuring the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube by using a side wall distance sensor.
Further, the method also comprises the following steps:
and measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube by using a bottom distance sensor.
Further, the method also comprises the following steps:
and acquiring the gravity signal of the test tube in the test tube lattice in real time through a gravity sensor.
Further, the method also comprises the following steps:
calculating the mass of the blood according to the gravity of the empty test tube and the gravity of the centrifuged test tube;
calculating the volume of blood based on the mass of blood;
calculating the diameter of the test tube according to the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube and the diameter of the rigid plastic shell;
calculating the height of the blood liquid level in the test tube according to the diameter of the test tube;
calculating the height of the liquid level of the plasma and the height of the midpoint of the plasma according to the height of the liquid level of the blood and the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube;
and adjusting the height position of the color sensor according to the plasma liquid level height and the plasma midpoint height.
Further, the step of adjusting the height position of the color sensor according to the plasma liquid level height and the plasma midpoint height comprises the following steps:
acquiring an initial starting position of a color sensor, and calculating the distance between the initial starting position and the bottom of the hard plastic shell;
calculating the moving height of the color sensor according to the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube, the height of the blood liquid level and the distance between the initial starting position and the bottom of the hard plastic shell;
calculating the number of turns of the power wheel according to the moving height of the color sensor;
generating a working control signal of the motor through a signal processing system according to the rotating number of turns of the power wheel;
and a signal processing system sends a working control signal to the motor to control the motor to rotate so as to adjust the height position of the color sensor.
The invention has the beneficial effects that: the device is additionally provided with the color sensor, so that the color signal of the plasma in the test tube can be obtained in real time, and the detection result of plasma chyle and hemolysis is obtained by matching with a signal processing system, so that the accuracy is high; in addition, the motor starts to work according to the control signal of the signal processing system, so that the power wheel is driven to rotate, the height position of the color sensor is adjusted by matching the fixing force wheel and the double chains, blood samples of test tubes of different specifications can be detected, and the practicability is high.
Drawings
FIG. 1 is a functional block diagram of an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of an embodiment of the present invention;
FIG. 3 is a schematic diagram of the connection of a fixed force wheel and a power wheel according to an embodiment of the invention.
Detailed Description
The invention will be further explained and explained with reference to the drawings and the embodiments in the description. The step numbers in the embodiments of the present invention are set for convenience of illustration only, the order between the steps is not limited at all, and the execution order of each step in the embodiments can be adaptively adjusted according to the understanding of those skilled in the art.
Referring to fig. 1, the embodiment of the invention provides a plasma chyle and hemolysis detection device suitable for test tubes of multiple specifications, which comprises a base, wherein a signal processing system, a power supply and a motor are arranged in the base, a plurality of test tube grids are arranged on the base, hard plastic shells are arranged on the test tube grids, color sensors are arranged on the side wall or the rear wall of each hard plastic shell, a fixing force wheel is arranged above each color sensor, a power wheel is arranged below each color sensor, the fixing force wheel and the power wheel are connected through double chains, and the color sensors are positioned between the double chains;
the color sensor is used for acquiring color sensing signals of a blood sample in a test tube placed in the test tube lattice in real time;
the signal processing system is used for generating a detection result of the chyle degree and the hemolysis degree of the plasma according to the blood color sensing signal; triggering a corresponding control signal, and then sending the control signal to the motor;
the motor is used for rotating by a corresponding amplitude according to a control signal of the signal processing system so as to drive the power wheel to rotate by a corresponding number of turns, so that the height position of the color sensor is adjusted;
and the power supply is used for providing working power supply signals for the signal processing system, the motor and the color sensor.
Further as a preferred embodiment, a side wall distance sensor is arranged on one side of the inner side wall of the hard plastic shell;
the side wall distance sensor is used for measuring the distance between the side wall of the inner side of the rigid plastic shell and the side wall of the test tube.
Further as a preferred embodiment, the bottom of the hard plastic shell is provided with a bottom distance sensor;
the bottom distance sensor is used for measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube.
Further as a preferred embodiment, a gravity sensor is further arranged on the hard plastic shell;
wherein, the gravity inductor is used for acquiring the gravity signal of the test tube in the test tube lattice in real time.
Based on the device shown in fig. 1, the embodiment of the invention also provides a method for detecting plasma chyle and hemolysis of a multi-specification test tube, which comprises the following steps:
acquiring a color sensing signal of a blood sample in a test tube placed in a test tube lattice in real time through a color sensor;
triggering a corresponding control signal through a signal processing system according to the blood color sensing signal, and sending the control signal to the motor;
the motor rotates by a corresponding amplitude according to a control signal of the signal processing system, and then drives the power wheel to rotate by a corresponding number of turns so as to realize the height position adjustment of the color sensor;
the signal processing system, the motor and the color sensor are provided with working power supply signals through a power supply.
Further as a preferred embodiment, the method further comprises the following steps:
and measuring the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube by using a side wall distance sensor.
Further as a preferred embodiment, the method further comprises the following steps:
and measuring the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube by using a bottom distance sensor.
Further as a preferred embodiment, the method further comprises the following steps:
and acquiring the gravity signal of the test tube in the test tube lattice in real time through a gravity sensor.
Further as a preferred embodiment, the method further comprises the following steps:
calculating the mass of the blood according to the gravity of the empty test tube and the gravity of the centrifuged test tube;
calculating the volume of blood based on the mass of blood;
calculating the diameter of the test tube according to the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube and the diameter of the rigid plastic shell;
calculating the height of the blood liquid level in the test tube according to the diameter of the test tube;
calculating the height of the liquid level of the plasma and the height of the midpoint of the plasma according to the height of the liquid level of the blood and the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube;
and adjusting the height position of the color sensor according to the plasma liquid level height and the plasma midpoint height.
Further, as a preferred embodiment, the step of adjusting the height position of the color sensor according to the plasma level height and the plasma midpoint height includes the following steps:
acquiring an initial starting position of a color sensor, and calculating the distance between the initial starting position and the bottom of the hard plastic shell;
calculating the moving height of the color sensor according to the distance between the bottom of the inner side of the hard plastic shell and the bottom of the test tube, the height of the blood liquid level and the distance between the initial starting position and the bottom of the hard plastic shell;
calculating the number of turns of the power wheel according to the moving height of the color sensor;
generating a working control signal of the motor through a signal processing system according to the rotating number of turns of the power wheel;
and a signal processing system sends a working control signal to the motor to control the motor to rotate so as to adjust the height position of the color sensor.
The working principle of the detection device for plasma chyle and hemolysis suitable for the multi-specification test tube of the invention is explained in detail below with the accompanying drawings of the specification:
as shown in fig. 2, the color sensor 1.4 is located on the side wall or the rear wall of the rigid plastic shell 1.1;
a fixed power wheel 1.8 and a power wheel 1.9 are arranged above the side wall or the rear wall of the hard plastic shell 1.1;
as shown in figure 3, the fixed force wheel 1.8 is connected with the power wheel 1.9 through double chains, the color sensor 1.4 is positioned between the double chains, and the movement of the double chains can drive the color sensor 1.4 to move up and down on the hard plastic shell 1.1.
A side wall distance sensor 1.6 is additionally arranged on the left side or the right side or the front side and the rear side of the inner side wall of the rigid plastic shell 1.1 and used for measuring the distance between the inner side wall of the rigid plastic shell 1.1 and the side wall of the test tube.
A bottom distance sensor 1.7 is added in the middle of the bottom of the inner side of the rigid plastic shell 1.1 and is used for measuring the distance between the bottom of the inner side of the rigid plastic shell 1.1 and the bottom of the test tube.
Because the same collection test tube but different blood volumes of adopting or use test tube height and/or size when gathering the sample inequality, it is unsettled to lead to plasma in the test tube for the position of test tube check after the centrifugation, therefore color inductor 1.4 need constantly adjust the height in the test tube check, just can effectively discern the colour of plasma in the test tube. The invention can automatically adjust the height of the color sensor 1.4 according to the test tube after being placed in the centrifuge, and has high practicability.
In addition, as shown in fig. 2, the detection device of the present invention comprises a test tube 1, a signal processing system 2, a base 3, a power source 4, a storage 5, and a display 7; test tube lattice 1 is the cuboid structure of adiactinic top open-ended, and blood sample test tube 6 after a centrifugation is placed to each test tube lattice 1, test tube lattice 1 is used for responding to the information of blood sample test tube 6 after the centrifugation and gives signal processing system 2 with information transmission, a plurality of test tube lattices 1 can be settled to base 3, signal processing system 2 is arranged in receiving gravity inductor 1.2, RFID chip reader 1.3 and color inductor 1.4's signal and will handle back information transmission to display 7, power 4 is arranged in providing electric power for signal processing system 2, gravity inductor 1.2, color inductor 1.4, RFID chip reader 1.3, yellow-light 1.5 and display 7.
Preferably, the test tube lattice 1 consists of a hard plastic shell 1.1, a gravity sensor 1.2, a color sensor 1.4, an RFID chip reader 1.3 and a yellow light lamp 1.5, wherein the hard plastic shell 1.1 is a cuboid with an open upper end, and the hard plastic shell 1.1 has a round upper end; the diameter of the opening at the upper end of the hard plastic shell 1.1 is larger than the diameter of the centrifuged blood sample test tube 6 and smaller than the diameter of the centrifuged blood sample test tube 6 cap.
Hard plastic shell 1.1 upper end opening inner wall passes through the 6 wall contacts of blood sample test tube after elastic material and centrifugation, and blood sample test tube 6 after both accessible elastic material fixed centrifugation can avoid outside light source to get into again and influence colour inductor 1.4 response result in the test tube check 1, the optional black silica gel that uses of elastic material, the opening of silica gel slightly is less than the external diameter of test tube.
Gravity inductor 1.2 is located stereoplasm plastic shell 1.1 upper end for whether there is gravity above the response test tube check 1, and send signal processing system 2 with gravity signal. When gravity exists on the test tube lattice 1, the test tube lattice 1 is inserted with the centrifuged blood sample test tube 6, and when no gravity exists above the test tube lattice 1, the test tube lattice 1 is not inserted with the centrifuged blood sample test tube 6.
The RFID chip reader 1.3 is located on the left side of the rigid plastic shell 1.1, and after the test tube lattice 1 is inserted into the centrifuged blood sample test tube 6, the RFID chip reader 1.3 reads information of a built-in RFID chip tag on the centrifuged blood sample test tube 6 and sends the information to the signal processing system 2.
The color sensor 1.4 is located on the inner wall of the front side of the rigid plastic shell 1.1, and the color sensor 1.4 is used for sensing the RGB value of the plasma color in the centrifuged blood sample tube 6 and sending the information to the signal processing system 2.
The yellow light lamp 1.5 is located at the bottom of the inner side of the hard plastic shell 1.1, and the yellow light lamp 1.5 is used for providing a light source for the color sensor 1.4.
The signal processing system 2 is positioned in the base 3, the signal processing system 2 is used for receiving the information of the gravity sensor 1.2, the color sensor 1.4 and the RFID chip reader 1.3 and sending the processed information to the display 7, when the gravity sensor 1.2 senses that a gravity signal exists above the test tube lattice 1, the signal processing system 2 sends a signal to the RFID chip reader 1.3, the RFID chip reader 1.3 reads information of a built-in RFID chip label on the centrifuged blood sample test tube 6 and sends the read information to the signal processing system 2, the signal processing system 2 sends the read information to the display 7, meanwhile, the signal processing system 2 sends signals to the color sensor 1.4 and the yellow light lamp 1.5, the yellow light lamp 1.5 is turned on, the color sensor 1.4 senses the RGB value of the blood plasma and sends the RGB value to the signal processing system 2, the signal processing system 2 obtains the degree of chyle and the degree of hemolysis of the detected plasma and sends the results to a display 7.
The power supply 4 is located in the base 3, and the power supply 4 is used for providing power for the signal processing system 2, the gravity sensor 1.2, the color sensor 1.4, the RFID chip reader 1.3, the yellow light lamp 1.5 and the display 7.
The storage device 5 is located in the base 3 and used for storing test tube information and the chyle degree and the hemolysis degree of plasma in the test tube.
The display 7 is positioned in front of the upper end of the test tube lattice 1 and is used for displaying the information of the centrifuged blood sample test tube 6 sent by the signal processing system 2 and the chyle degree and the hemolysis degree of the plasma.
The following describes in detail the specific implementation steps of the method of the present invention for a device for detecting plasma chyle and hemolysis in a multi-format test tube:
s1, calculating the quality of blood;
firstly, placing an empty test tube for blood collection in the device, and reading the gravity W1 of the empty test tube by a gravity sensor in the device;
then, placing the centrifuged test tube into the device, and reading the gravity W2 of the centrifuged test tube by a gravity sensor;
finally, the two obtained gravity change results Δ W ═ are calculated (W)2-W1) Obtaining the quality of the collected blood
Figure GDA0003351925410000071
Wherein g is 9.8N/KG.
S2, calculating the volume of the blood;
firstly, according to the density formula
Figure GDA0003351925410000072
Calculating the volume of blood
Figure GDA0003351925410000073
Since the relative density of blood with respect to water is 1.05-1.06. The average relative density of 1.055 was selected as the blood density in this example. Thus, the volume of blood is calculated as
Figure GDA0003351925410000074
S3, calculating the diameter of the test tube;
firstly, the diameter d of the rigid plastic shell is measured by a side wall distance sensor1And the distance L between the rigid plastic shell and the test tube wall1And the diameter calculation result of the outer side wall of the test tube is d2=d1-2×L1So that the calculation of the inside diameter of the test tube is d3=d2-2L2Wherein L is2The thickness of the blood sampling test tube is usually 1 mm, and the area of the blood level in the test tube is calculated
Figure GDA0003351925410000075
S4, calculating the height H of the blood in the test tube;
the height of the collected blood in the test tube is
Figure GDA0003351925410000076
Because the blood in human body is composed of plasma and blood cells, the volume percentage of the blood cells in the blood is called hematocrit, the hematocrit of a normal adult male is 40% -50%, the hematocrit of a normal adult female is 37% -48%, and the height of the blood cells in a test tube after centrifugation is about equal to that of the blood cells in the test tube after centrifugation
Figure GDA0003351925410000081
I.e. the height of the plasma is
Figure GDA0003351925410000086
S5, calculating the height H of the plasma relative to the test tube lattice3And plasma mid-point height H4
Firstly, the distance H between the bottom of the rigid plastic shell and the bottom of the test tube is measured by a bottom distance sensor1The distance of the plasma from the bottom of the rigid plastic shell
Figure GDA0003351925410000082
The calculated plasma midpoint height is:
Figure GDA0003351925410000083
s6, calculating the moving height of the color sensor;
when the device is just started, the color sensor of this embodiment is disposed at a fixed position on the device, namely, an initial starting position, between the initial starting position and the bottom of the rigid plastic shellAt a distance H5The color sensor of the present invention can obtain the color of plasma at different locations, wherein:
1) when the device needs to start the color sensor to obtain the color of the blood plasma in the whole test tube, the color sensor is controlled to ascend at a distance
Figure GDA0003351925410000084
Start recording color at the time of and at a rising distance L3=H1+H-H5The recording of the color is stopped, and the color sensing signal obtained by the color sensor in the ascending distance is the color of the blood plasma in the whole test tube.
2) When the device needs to start the color sensor to sense the color of the middle part of the blood plasma, the color sensor is controlled to ascend at a distance
Figure GDA0003351925410000085
The color is recorded.
In the present invention, the color sensor rises by a distance L3Equal to the rotating perimeter of the power wheel, so that the ascending distance L of the color sensor can be accurately controlled by controlling the rotating angle of the power wheel3
After the plasma color sensing operation is completed, the color sensor is controlled to return to the initial starting position in the device to wait for the next sensing operation.
The following describes in detail another embodiment of the method of the present invention for detecting plasma chyle and hemolysis in a multi-size test tube.
Since blood in the human body consists of main plasma and blood cells, the mass of the blood cells is greater than that of the plasma, under the action of centrifugal force. The blood cell layer is arranged at the bottom of the test tube, the blood plasma layer is arranged above the blood cell layer, the respective colors of the blood cell layer and the blood plasma layer are uniformly distributed, but the color of the blood cell layer is obviously different from that of the blood plasma layer. Therefore, the color sensor scans and records the RGB values in the test tube from the bottom of the test tube to obtain RGB value 1, RGB value 2, RGB value 3, RGB value 4, RGB value 5, RGB value 6, RGB value 7 and RGB value 8, respectively.
When the RGB value 1 ≠ RGB value 2 ≠ RGB value 3 ≠ RGB value 4 ≠ RGB value 5 ≠ RGB value 6 ≠ RGB value 7 ≠ RGB value 8, then:
the RGB value 1 is the color value of the test tube lattice;
the RGB values 2, 3 and 4 are the color values of the blood cell layer in the test tube lattice;
the RGB value 5, the RGB value 6 and the RGB value 7 are color values of the plasma layer in the test tube lattice;
the RGB value 8 is the color value of the tube lattice after being inserted into the tube.
Therefore, the RGB value 6 is compared with the RGB values pre-stored in the database, and the database feeds back the chyle index and the degree of hemolysis corresponding to the RGB values.
When the RGB value 1 ═ RGB value 2 ═ RGB value 3 ≠ RGB value 4 ≠ RGB value 5 ≠ RGB value 6 ≠ RGB value 7 ≠ RGB value 8, then:
the RGB value 1, the RGB value 2, the RGB value 3 and the RGB value 4 are color values of the blood cell layer in the test tube lattice;
the RGB value 5, the RGB value 6 and the RGB value 7 are color values of the plasma layer in the test tube lattice;
the RGB value 8 is the color value of the tube lattice after being inserted into the tube.
Therefore, the RGB value 6 is compared with RGB in the database, and the database feeds back the chylomicron index and the degree of hemolysis corresponding to the RGB value.
In addition, the invention can also measure the distance H between the bottom of the rigid plastic shell and the bottom of the test tube through the bottom distance sensor1When the device is just started, the color sensor of this embodiment is disposed at a fixed position on the device, i.e., an initial starting position, and the distance between the initial starting position and the bottom of the rigid plastic shell is H5When H is present5>H1While, the color sensor is lowered H5-H1The distance of (d); when H is present5<H1While, the color sensor rises H1-H5The distance of (d); at this time, the color values of the test tube lattices are recorded, and then RGB values 1, 2, 3, 4, 5, 6, 7 and 8 are obtained.
When the RGB value 1 ═ RGB value 2 ═ RGB value 3 ≠ RGB value 4 ≠ RGB value 5 ≠ RGB value 6 ≠ RGB value 7 ≠ RGB value 8, then:
the RGB value 1, the RGB value 2, the RGB value 3 and the RGB value 4 are color values of the blood cell layer in the test tube lattice;
the RGB value 5, the RGB value 6 and the RGB value 7 are color values of the plasma layer in the test tube lattice;
the RGB value 8 is the color value of the tube lattice after being inserted into the tube.
Therefore, the RGB value 6 is compared with RGB in the database, and the database feeds back the chylomicron index and the degree of hemolysis corresponding to the RGB value.
In summary, the invention has the following advantages:
1. the color sensor can accurately distinguish slight color changes, can objectively observe the chyle degree and the hemolysis degree of the plasma, and particularly can avoid the conditions of non-uniform standard and non-uniform judgment result caused by subjective factors of operators when the collected blood sample has chyle blood and hemolysis simultaneously;
2. the whole test tube lattice is sealed and light-proof, natural light cannot enter the test tube lattice, and meanwhile, a light source required by the color sensor is a yellow light lamp, so that the decomposition of medicines or metabolites in blood plasma under the natural light can be effectively prevented, the detection error is avoided, and the quality of a sample is improved;
3. the motor starts to work according to the control signal of the signal processing system, so that the power wheel is driven to rotate, the height position of the color sensor is adjusted by matching the fixing force wheel and the double chains, blood samples of test tubes of different specifications can be detected, and the motor is wide in application range and high in practicability.
4. According to the invention, the distance between the rigid plastic shell and the test tube is sensed in real time through the side wall distance sensor and the bottom distance sensor, the signal processing system triggers corresponding control signals according to the sensed distance signals to control the work of the modules such as the motor and the display, so that collision between the test tube and the rigid plastic shell due to the close distance can be prevented, and the safety is high.
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (4)

1.适用于多规格试管的血浆乳糜和溶血的检测装置,其特征在于:包括底座,所述底座内设有信号处理系统、电源和电动机,所述底座上设有多个试管格,所述试管格上设有硬质塑料壳,所述硬质塑料壳侧壁或者后壁上设有颜色感应器,所述颜色感应器上方安装有固定力轮,所述颜色感应器下方安装有动力轮,所述固定力轮和动力轮通过双链条连接,所述颜色感应器位于双链条之间;1. be applicable to the detection device of the plasma chyle and hemolysis of multi-specification test tubes, it is characterized in that: comprise base, described base is provided with signal processing system, power supply and electric motor, described base is provided with a plurality of test tube grids, described There is a hard plastic shell on the test tube grid, a color sensor is arranged on the side wall or rear wall of the hard plastic shell, a fixed force wheel is installed above the color sensor, and a power wheel is installed below the color sensor , the fixed force wheel and the power wheel are connected by double chains, and the color sensor is located between the double chains; 其中,所述颜色感应器,用于实时获取放置在试管格中试管内血液样本的颜色感应信号;Wherein, the color sensor is used to acquire the color sensing signal of the blood sample in the test tube placed in the test tube grid in real time; 所述信号处理系统,用于根据血液颜色感应信号,生成血浆的乳糜程度及溶血程度检测结果;并触发相应的控制信号,然后将控制信号发送至电动机;The signal processing system is used to generate the detection results of the degree of chyle and the degree of hemolysis of the plasma according to the blood color sensing signal; and trigger the corresponding control signal, and then send the control signal to the motor; 所述电动机,用于根据信号处理系统的控制信号转动相应幅度,进而带动动力轮转动相应的圈数,以实现对颜色感应器的高度位置调整;The motor is used for rotating the corresponding amplitude according to the control signal of the signal processing system, and then driving the power wheel to rotate the corresponding number of turns, so as to realize the adjustment of the height position of the color sensor; 所述电源,用于为信号处理系统、电动机和颜色感应器提供工作电源信号;The power supply is used to provide working power signals for the signal processing system, the motor and the color sensor; 所述硬质塑料壳的内侧壁的一侧设有侧壁距离传感器;A side wall distance sensor is provided on one side of the inner side wall of the rigid plastic shell; 其中,所述侧壁距离传感器,用于测量硬质塑料壳内侧侧壁与试管侧壁之间的距离;所述硬质塑料壳的底部设有底部距离传感器;Wherein, the side wall distance sensor is used to measure the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube; the bottom of the rigid plastic shell is provided with a bottom distance sensor; 其中,所述底部距离传感器,用于测量硬质塑料壳内侧底部与试管底部之间的距离;所述硬质塑料壳上还设有重力感应器;Wherein, the bottom distance sensor is used to measure the distance between the inner bottom of the rigid plastic shell and the bottom of the test tube; the rigid plastic shell is also provided with a gravity sensor; 其中,所述重力感应器,用于实时获取试管格中试管的重力信号;Wherein, the gravity sensor is used to obtain the gravity signal of the test tube in the test tube grid in real time; 所述硬质塑料壳内侧的底部设置有黄光灯,所述黄光灯用于给所述颜色感应器提供光源;所述试管格为不透光的上方开口的长方体结构。The bottom of the inner side of the rigid plastic shell is provided with a yellow light, and the yellow light is used to provide a light source for the color sensor; the test tube grid is a cuboid structure with an opaque upper opening. 2.适用于多规格试管的血浆乳糜和溶血的检测装置的方法,其特征在于:应用于如权利要求1所述的适用于多规格试管的血浆乳糜和溶血的检测装置,所述方法包括以下步骤:2. The method for the detection device of plasma chyle and hemolysis suitable for multi-specification test tubes, characterized in that: applied to the detection device for plasma chyle and hemolysis of multi-specification test tubes as claimed in claim 1, the method comprises the following step: 通过颜色感应器实时获取放置在试管格中试管内血液样本的颜色感应信号;Obtain the color sensing signal of the blood sample placed in the test tube in real time through the color sensor; 根据血液颜色感应信号,通过信号处理系统触发相应的控制信号,并将控制信号发送至电动机;According to the blood color sensing signal, the corresponding control signal is triggered through the signal processing system, and the control signal is sent to the motor; 电动机根据信号处理系统的控制信号转动相应幅度,进而带动动力轮转动相应的圈数,以实现对颜色感应器的高度位置调整;The motor rotates the corresponding amplitude according to the control signal of the signal processing system, and then drives the power wheel to rotate the corresponding number of turns to realize the height position adjustment of the color sensor; 通过电源为信号处理系统、电动机和颜色感应器提供工作电源信号;Provide working power signal for signal processing system, motor and color sensor through power supply; 还包括以下步骤:Also includes the following steps: 通过侧壁距离传感器测量硬质塑料壳内侧侧壁与试管侧壁之间的距离;Measure the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube through the side wall distance sensor; 通过底部距离传感器测量硬质塑料壳内侧底部与试管底部之间的距离;Measure the distance between the inner bottom of the rigid plastic shell and the bottom of the test tube by the bottom distance sensor; 通过重力感应器实时获取试管格中试管的重力信号。The gravity signal of the test tube in the test tube grid is obtained in real time through the gravity sensor. 3.根据权利要求2所述的适用于多规格试管的血浆乳糜和溶血的检测装置的方法,其特征在于:还包括以下步骤:3. the method for the detection device of plasma chyle and hemolysis suitable for multi-specification test tubes according to claim 2, is characterized in that: also comprises the following steps: 根据空试管的重力和离心后的试管重力,计算血液的质量;Calculate the mass of blood according to the gravity of the empty test tube and the gravity of the test tube after centrifugation; 根据血液的质量计算血液的体积;Calculate the volume of blood based on its mass; 根据硬质塑料壳内侧侧壁与试管侧壁之间的距离以及硬质塑料壳的直径,计算试管的直径;Calculate the diameter of the test tube according to the distance between the inner side wall of the rigid plastic shell and the side wall of the test tube and the diameter of the rigid plastic shell; 根据试管的直径计算试管内的血液液面高度;Calculate the blood level in the test tube according to the diameter of the test tube; 根据血液液面高度以及硬质塑料壳内侧底部与试管底部之间的距离,计算血浆液面高度和血浆中点高度;Calculate the plasma level and the plasma midpoint height according to the blood level and the distance between the inner bottom of the rigid plastic shell and the bottom of the test tube; 根据血浆液面高度和血浆中点高度,对颜色感应器的高度位置进行调整。Adjust the height position of the color sensor according to the plasma level and the plasma midpoint height. 4.根据权利要求3所述的适用于多规格试管的血浆乳糜和溶血的检测装置的方法,其特征在于:所述根据血浆液面高度和血浆中点高度,对颜色感应器的高度位置进行调整这一步骤,包括以下步骤:4. The method for the detection device of plasma chyle and hemolysis suitable for multi-specification test tubes according to claim 3, characterized in that: the height position of the color sensor is carried out according to the height of the plasma level and the height of the midpoint of the plasma. Adjust this step to include the following steps: 获取颜色感应器的初始启动位置,并计算所述初始启动位置与硬质塑料壳底部之间的距离;Obtain the initial starting position of the color sensor, and calculate the distance between the initial starting position and the bottom of the hard plastic shell; 根据硬质塑料壳内侧底部与试管底部之间的距离、血液液面高度以及初始启动位置与硬质塑料壳底部之间的距离,计算颜色感应器的移动高度;Calculate the moving height of the color sensor according to the distance between the inner bottom of the hard plastic case and the bottom of the test tube, the height of the blood level and the distance between the initial start position and the bottom of the hard plastic case; 根据颜色感应器的移动高度,计算动力轮的转动圈数;Calculate the number of turns of the power wheel according to the moving height of the color sensor; 根据动力轮的转动圈数,通过信号处理系统生成电动机的工作控制信号;According to the number of turns of the power wheel, the working control signal of the motor is generated through the signal processing system; 通过信号处理系统向电动机发出工作控制信号,控制电动机转动,以对颜色感应器的高度位置进行调整。A working control signal is sent to the motor through the signal processing system to control the rotation of the motor to adjust the height position of the color sensor.
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