CN1096264C - 类胡萝卜素和维生素的稳定含水增溶物 - Google Patents

类胡萝卜素和维生素的稳定含水增溶物 Download PDF

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Publication number
CN1096264C
CN1096264C CN97109610A CN97109610A CN1096264C CN 1096264 C CN1096264 C CN 1096264C CN 97109610 A CN97109610 A CN 97109610A CN 97109610 A CN97109610 A CN 97109610A CN 1096264 C CN1096264 C CN 1096264C
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CN
China
Prior art keywords
vitamin
carotenoid
hydrotrope
content
percentage
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Expired - Fee Related
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CN97109610A
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English (en)
Chinese (zh)
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CN1165653A (zh
Inventor
K·科尔特
F·鲁恩格
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BASF SE
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BASF SE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN97109610A 1996-03-11 1997-03-11 类胡萝卜素和维生素的稳定含水增溶物 Expired - Fee Related CN1096264C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19609477.1 1996-03-11
DE19609477A DE19609477A1 (de) 1996-03-11 1996-03-11 Stabile wäßrige Solubilisate von Carotinoiden und Vitamine

Publications (2)

Publication Number Publication Date
CN1165653A CN1165653A (zh) 1997-11-26
CN1096264C true CN1096264C (zh) 2002-12-18

Family

ID=7787924

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97109610A Expired - Fee Related CN1096264C (zh) 1996-03-11 1997-03-11 类胡萝卜素和维生素的稳定含水增溶物

Country Status (7)

Country Link
US (1) US5891907A (OSRAM)
EP (1) EP0800825A1 (OSRAM)
JP (1) JPH09249554A (OSRAM)
CN (1) CN1096264C (OSRAM)
AU (1) AU1620497A (OSRAM)
CA (1) CA2199415A1 (OSRAM)
DE (1) DE19609477A1 (OSRAM)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19653410A1 (de) 1996-12-20 1998-06-25 Basf Ag Verwendung von Carotinoid-Solubilisaten zum Färben von Lebensmitteln und pharmazeutischen Zubereitungen
AU752468B2 (en) 1997-04-04 2002-09-19 Phyllis E. Bowen Lutein esters having high bioavailability
AT408186B (de) * 1998-12-15 2001-09-25 Sanochemia Pharmazeutika Ag Wässerige zubereitung von beta-carotin
PT1171100E (pt) * 1999-04-13 2003-11-28 Leo Pharma As Composicao farmaceutica solubilizada para administracao parenteral
IN2000KO00299A (OSRAM) * 1999-05-28 2005-11-18 Johnson & Johnson Consumer
US6582721B1 (en) 1999-09-17 2003-06-24 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
US8137699B2 (en) * 2002-03-29 2012-03-20 Trustees Of Princeton University Process and apparatuses for preparing nanoparticle compositions with amphiphilic copolymers and their use
DE10126446A1 (de) * 2001-05-31 2002-12-05 Cognis Deutschland Gmbh Haarpflegemittel mit natürlichen Ölen
US6635293B2 (en) * 2001-10-23 2003-10-21 Kemin Foods, L.C. Finely dispersed carotenoid suspensions for use in foods and a process for their preparation
DE10221212A1 (de) * 2002-05-13 2003-11-27 Andreas Maack Sporopollenin enthaltende lösliche Zusammensetzung und Verwendung
WO2004012707A1 (de) * 2002-07-24 2004-02-12 Basf Aktiengesellschaft Suspensionen von salzen der ascorbinsäure und ihre verwendung als antioxidantien
EP1532108B1 (en) * 2002-07-29 2016-06-29 Cardax Pharma, Inc. Astaxanthin esters for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US7763649B2 (en) * 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US7723327B2 (en) * 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
GB0218932D0 (en) * 2002-08-14 2002-09-25 Zoolife Internat Ltd Composition for dietary enrichment
DE10243437A1 (de) * 2002-09-18 2004-04-29 Pm-International Ag Kosmetische Formulierung
US20050037115A1 (en) * 2003-08-15 2005-02-17 Linda Fullmer Carotenoid nanodispersions for use in water-based systems and a process for their preparation
WO2005102356A1 (en) * 2004-04-14 2005-11-03 Hawaii Biotech, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US7351424B2 (en) * 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
WO2006047475A2 (en) * 2004-10-25 2006-05-04 Sytera, Inc. Detection and analysis of ophthalmically-relevant fluorescent molecules
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
JP2007270073A (ja) * 2006-03-31 2007-10-18 Fujifilm Corp エマルジョン組成物
US7435846B2 (en) 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
JP5019885B2 (ja) * 2007-01-05 2012-09-05 富士フイルム株式会社 分散組成物及びスキンケア用化粧料並びに分散組成物の製造方法
JP5046756B2 (ja) * 2007-06-27 2012-10-10 富士フイルム株式会社 分散組成物及びスキンケア用化粧料並びに分散組成物の製造方法
ES2361276T5 (es) 2007-01-16 2017-06-09 Basf Se Formulaciones líquidas, que contienen carotenoides
DE502008002299D1 (de) * 2007-02-23 2011-02-24 Brain Biotechnology Res & Information Network Ag Verfahren zur geschmacksmodulation von stofflichen zusammensetzungen, die mindestens einen high intensity sweetener (his) enthalten
DE202008006492U1 (de) 2007-02-23 2008-08-21 Basf Se Verwendung von wasserdispergierbaren Carotinoid-Nanopartikeln als Geschmacksmodulatoren, Geschmacksmodulatoren, enthaltend wasserdispergierbare Carotinoid-Nanopartikel
ATE494799T1 (de) * 2007-02-23 2011-01-15 Brain Biotechnology Res & Information Network Ag Verwendung von wasserdispergierbaren carotinoid- nanopartikeln als geschmacksmodulatoren, geschmacksmodulatoren, enthaltend wasserdispergierbare carotinoid-nanopartikel, und verfahren zur geschmacksmodulation
JP5101193B2 (ja) * 2007-07-06 2012-12-19 富士フイルム株式会社 化粧品組成物
WO2009068432A1 (de) 2007-11-29 2009-06-04 Basf Se Pulverförmige carotinoidzubereitung für die färbung von getränken
JP5728152B2 (ja) * 2008-07-07 2015-06-03 株式会社ファンケル 乾燥リポソーム製剤
EP2151231B1 (de) * 2008-08-05 2017-08-02 PM-International AG Kosmetische Formulierung
DK2343986T4 (da) 2008-10-07 2021-07-26 Basf Se Brugsklar, stabil emulsion
DK2192160T3 (en) * 2008-12-01 2016-12-12 Aquanova Ag INTEGRATED oxidation of micelles FOR NATURAL DYES
FR2949063B1 (fr) * 2009-08-11 2011-09-30 Pf Medicament Composition pharmaceutique comprenant un ester de dha destinee a etre administree par voie parenterale
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
US9849096B2 (en) 2013-03-28 2017-12-26 Omniactive Health Technologies Limited Neuroprotective effect of carotenoids in brain
AT514764A1 (de) 2013-09-02 2015-03-15 Sanochemia Ag Beta-Carotin Zubereitung
US9622970B2 (en) * 2014-05-08 2017-04-18 Yaguang Liu Pharmaceutical composition containing lutein and antioxidant for treating and preventing human disease
JP7774292B2 (ja) * 2018-11-26 2025-11-21 オルファニクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 水性の小児用レチノール製剤
AT521983A1 (de) * 2018-11-26 2020-06-15 Orphanix Gmbh Wässrige pädiatrische Retinolpräparate
CN111568858A (zh) * 2020-04-30 2020-08-25 佛山科学技术学院 一种虾青素水溶液的制备方法
CN111991301A (zh) * 2020-09-21 2020-11-27 四川梅奥由享生物科技有限公司 具有抗炎美白修复保湿多重功效的乳液
CN114081069A (zh) * 2021-11-11 2022-02-25 光明乳业股份有限公司 一种含虾青素的乳制品及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3048000A1 (de) * 1980-12-19 1982-07-15 Basf Ag Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung
DE4031094A1 (de) * 1990-10-02 1992-04-09 Basf Ag Verfahren zur herstellung von stabilen injizierbaren (beta)-carotin-solubilisaten
GB9219524D0 (en) * 1992-09-15 1992-10-28 Smithkline Beecham Plc Novel composition
CH685325A5 (de) * 1994-01-04 1995-06-15 Marigen Sa Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit schwer löslichen Carotinen.

Also Published As

Publication number Publication date
EP0800825A1 (de) 1997-10-15
CA2199415A1 (en) 1997-09-11
DE19609477A1 (de) 1997-09-18
AU1620497A (en) 1997-09-18
CN1165653A (zh) 1997-11-26
JPH09249554A (ja) 1997-09-22
US5891907A (en) 1999-04-06

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