CN109620861A - A kind of itch-stopping bactericidal maintenance liquid and preparation method thereof - Google Patents
A kind of itch-stopping bactericidal maintenance liquid and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Abstract
The present invention discloses a kind of itch-stopping bactericidal maintenance liquid and preparation method thereof, wherein, itch-stopping bactericidal maintenance liquid includes following components by weight percent: 0.02~0.2 part of alkannin, 10~16 parts of tea tree ethereal oils, 0.1~0.8 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide, 5~10 parts of fat of Oromaius norvaehollandeae, 73~85 parts of base oils.The rotten foot bifurcation maintenance liquid for the treatment of provided by the invention is easy to use, has no toxic side effect, and itch-stopping bactericidal ability is strong, and can effectively facilitate the fast quick-recovery healing of site of disease skin.
Description
Technical field
The invention belongs to field of traditional Chinese medicine preparations more particularly to a kind of itch-stopping bactericidal maintenance liquid and preparation method thereof.
Background technique
Skin infection disease is the common disease for seriously affecting health of people, often perplexs the happy life of people, is stranded
Disturb the soul and spirit of people.
Some skin diseases be because fungi, bacterial skin infections etc. cause, common skin disease have psoriasis, eczema, dermatitis,
Neurodermatitis, verruca vulgaris, anaphylaxis erythema, scabies, whelk, tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, jock itch etc..In day
Often in life, foot is sealed in shoe lining, and not only easy infection tinea pedis also easily breeds germ.If not paying attention to the hygiene on foot, just
It is easy to cause various athlete's foots and dermopathic generation.Accurate perfect treatment can make people be full of to life have deep love for and oneself
Letter.
Existing Chinese medicine treats skin disease, and formula has single type or limitation or medicinal material composition compatibility unreasonable,
Or because imperfect to the extraction of its effective component during processing or processing or extraction is unreasonable, not in place, in certain journey
The effect of depth therapy is not achieved on degree, thus treatment is caused to be not thorough easy recurrence.Such as Publication No. CN104623252A
Chinese patent application discloses a kind of compound fenticonazole nitrate preparation and its application, by the way of Integrated TCM, reduces
Fenticonazole nitrate, toxic side effect are reduced, but said preparation is more using Chinese herb medicine component, lead to that the production cost increases.
There are also some existing Western medicine or Chinese medicine addition steroids or antibiotics different degrees of in treatment skin disease
Drug there are certain toxic side effect or is easy to produce antibody, and treatment is not achieved there are also some drugs and repairs diseased region
Purpose.
In addition to this, also lack the drug for foot's bacterium infection currently on the market, although portioned product has a constant current modulation
Effect, but toxin expelling sterilization is not thorough, and drug penetration is poor, can only kill except surface bacteria, leads to the course of disease repeatedly, cannot play thorough
The effect of bottom treatment.
Summary of the invention
The purpose of the present invention is to provide a kind of itch-stopping bactericidal maintenance liquid, good to the therapeutic effect of rotten foot bifurcation.
Itch-stopping bactericidal maintenance liquid of the present invention, in parts by weight, comprising:
Alkannin is added in the present invention, Asian puccoon is that China's pharmacopeia records clinical common traditional Chinese medicine, has antitumor, antioxygen
Change, antibacterial, it is anti-inflammatory, antiviral the effects of.The main effective component of Asian puccoon is naphthoquinone compound, i.e. alkannin
(Shikonin), clinic has been used for treatment acute hepatitis, chronic hepatitis, cirrhosis (ascites), treatment verruca plana, psoriasis and promotes wound
Healing.Preferably, alkannin is 0.1~0.2 part.
Derivative of the Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide (CAS:34096-83-8) as glycyrrhizic acid, polarity is between Radix Glycyrrhizae
Between acid and enoxolone, cell can be can smoothly enter into, in the intracorporal solubility of machine and transmembrane transport ability than glycyrrhizic acid and Radix Glycyrrhizae
Hypo acid is strong.It is anti-inflammatory antibacterial to assign its, restrain it is antipyretic, the effect of cooling and activating blood.Preferably, Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide is
0.4~0.8 part.
Tea tree ethereal oil is added, there is bactericidal antiphlogistic, convergence pore, treatment cold, cough, rhinitis, asthma and other effects.
Suitable for oiliness and acne-prone skin, treats suppurative wound and burn, tan severely, athlete's foot and dandruff.Preferably, tea tree ethereal oil 14
~16 parts.
Fat of Oromaius norvaehollandeae has powerful inflammation-diminishing function and outstanding skin permeability, and unsaturated fatty acid is high in pure fat of Oromaius norvaehollandeae
Up to 70%, wherein monomer unsaturated fatty acid accounts for the 40% of total fatty acids amount, also containing Omega (Omega) 3,6,7,9. these
The composition of fatty acid is unique in living nature, is to be most suitable for absorption of human body, closest to the pure day of human skin grease
Right ingredient, therefore penetrating power is preeminent, it can be by above-mentioned essential fatty acid and its Alphalin for naturally including, D, E, F, K2 are carried
It is absorbed into human body.Preferably, fat of Oromaius norvaehollandeae is 8~10 parts.
Above-mentioned effective component is dispersed in base oil, the base oil be selected from from the seed of plant, flower, rhizome or
The non-volatile grease extracted in fruit, Castor Oil skin can be directly used in skin massage, and the best base bottom of dilution essential oil
Oil.Common base oil has SIMMONDSIA CHINENSIS SEED OIL, Sweet Almond Oil, grape seed oil, olive oil etc..
SIMMONDSIA CHINENSIS SEED OIL: it has good permeability, as long as there is gap, can permeate；Also there is speciality resistant to high temperature, and
And molecules align and the grease of people are very similar, are the base oils that stability is high, ductility is particularly good, are suitble to Oily and hair
The skin of inflammation, eczema, chronic eczema, pimples.
Sweet Almond Oil: having good skin-friendly, and most delicate baby also can be used.And the spy containing high nutrition element
Matter is good moist and miscella.It is suitble to baby, stemness, wrinkle, acne and sensibility skin to use.
Grape seed oil: penetration is strong, and when can be used as facial massage and treatment, especially delicate and sensitive skin is oiliness, dark
Sore, acne-prone skin.Containing abundant vitaminF, minerals, protein, the moistening effect of skin can be enhanced, while can moisten, is soft
Skin, the salubrious non-greasy of quality are easily absorbed by skin.
Olive oil: it is rich in monounsaturated fatty acids, is exactly oleic acid.It can increase high-density lipoprotein cholesterol, a kind of
The good cholesterol flowed in our blood, and reduce bad cholesterol.It has blood vessel and joint there are also the effect of anti-inflammatory
Benefit, and rich in the black alcohols of the plant and polyphenols for having protective effect on cancer risk.
The present invention also provides the preparation methods of the itch-stopping bactericidal maintenance liquid, comprising: according to formula, in base oil
Alkannin, tea tree ethereal oil, Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide, fat of Oromaius norvaehollandeae is added, dissolution mixes.
Wherein, the temperature of dissolution is 45 DEG C~50 DEG C.
The beneficial effects of the present invention are:
Fat of Oromaius norvaehollandeae has powerful inflammation-diminishing function and outstanding skin permeability, adds tea tree ethereal oil, and flesh bottom of going directly is released
Dirt is put, the two and base oil especially SIMMONDSIA CHINENSIS SEED OIL can promote percutaneous absorption, can be well by alkannin and single Portugal
The effect of grape uronic acid enoxolone, reaches maximization.While reaching Quick itch stopping sterilization, moreover it is possible to while moisturizing water lock, it repairs
Multiple skin, makes the smooth exquisiteness of foot skin.In view of easy allergic human population, alkannin collocation Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide can
To play anti-allergic effects.
In formula composition of the invention, each ingredient interacts, wherein alkannin and Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide
Influence each other anti-inflammatory antibacterial antianaphylactic effect, and tea tree ethereal oil and alkannin influence each other skin repair effect, tea tree ethereal oil and
The fat of Oromaius norvaehollandeae calmness that influences each other is releived effect, and base oil and fat of Oromaius norvaehollandeae influence each other skin moisturizing water lock effect, and the present invention passes through
Recipe ingredient, and influence of the equilibrium composition additive amount to itch-stopping bactericidal and product appearance are reasonably selected, while maintaining preparation steady
It is qualitative.
Product of the present invention preferably has itch-stopping bactericidal, cooling and activating blood, anti-inflammatory antivirus plant ingredient, and has strong
The vegetable and animals oils of big skin-friendly, treatment and skin care are organically combined, and are excluded patient and are worried the impaired puzzlement of skin；It is easy to use,
It has no toxic side effect, itch-stopping bactericidal ability is strong, and can effectively facilitate the fast quick-recovery healing of site of disease skin, there is skin-care effect.
Specific embodiment
The technical solution that the present invention will be described in detail combined with specific embodiments below
Embodiment 1
In parts by weight, in 73.4 parts of olive oil, the alkannin of 0.2 part of addition, 16 parts of tea tree ethereal oil, 0.4 part
Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 2
In parts by weight, in 73.4 parts of Sweet Almond Oil, the alkannin of 0.2 part of addition, 16 parts of tea tree ethereal oil, 0.4
Part Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 3
In parts by weight, in 73.4 parts of grape seed oil, the alkannin of 0.2 part of addition, 16 parts of tea tree ethereal oil, 0.4
Part Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 4
In parts by weight, in 73.4 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.2 part of addition, 16 parts of tea tree ethereal oil, 0.4
Part Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 5
In parts by weight, in 79.4 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.2 part of addition, 10 parts of tea tree ethereal oil, 0.4
Part Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 6
In parts by weight, in 79.58 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.02 part of addition, 10 parts of tea tree ethereal oil,
0.4 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C of sufficiently dissolutions, stir evenly, cooling and standings, i.e.,
?.
Embodiment 7
In parts by weight, in 73.78 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.02 part of addition, 16 parts of tea tree ethereal oil,
0.2 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C of sufficiently dissolutions, stir evenly, cooling and standings, i.e.,
?.
Embodiment 8
In parts by weight, in 84.88 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.02 part of addition, 10 parts of tea tree ethereal oil,
0.1 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 5 parts of fat of Oromaius norvaehollandeae, 50 DEG C of sufficiently dissolutions, stir evenly, cooling and standings, i.e.,
?.
Embodiment 9
In parts by weight, in 73.58 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.02 part of addition, 16 parts of tea tree ethereal oil,
0.4 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C of sufficiently dissolutions, stir evenly, cooling and standings, i.e.,
?.
Embodiment 10
In parts by weight, in 73.5 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.1 part of addition, 16 parts of tea tree ethereal oil, 0.4
Part Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 11
In parts by weight, in 73.18 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.02 part of addition, 16 parts of tea tree ethereal oil,
0.8 part of Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C of sufficiently dissolutions, stir evenly, cooling and standings, i.e.,
?.
Embodiment 12
In parts by weight, in 73 parts of SIMMONDSIA CHINENSIS SEED OIL, the alkannin of 0.2 part of addition, 16 parts of tea tree ethereal oil, 0.8 part
Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide and 10 parts of fat of Oromaius norvaehollandeae, 50 DEG C sufficiently dissolution, stir evenly, cooling and standings to get.
Embodiment 13
The effect of the present embodiment measurement embodiment 1-4 maintenance liquid.
Treatment method: using maintenance liquid of the present invention in the morning, afternoon and evening daily, drips several drops in affected part, uniformly smears, massage a few minutes
Promote to absorb, one week as a treatment course, is used in conjunction 1-4 weeks.
40 rotten foot bifurcation patients are randomly selected, every 10 people is one group, the observation of curative effect after treating.
Slight measurement standard: there is itch but not acutely in affected part, and skin surface no longer deteriorates.
Obvious measurement standard: affected part has itch once in a while, and skin healing is slower.
Significant measurement standard: affected part stops itch, and skin healing is very fast.
Skin healing velocity standard: affected part skin after after one course for the treatment of of this product, seeing wound healing degree and healing is used
Skin exquisiteness degree.
Table 1
| Embodiment | The antipruritic situation in affected part | Skin healing speed | Moistening effect |
| 1 | Without positive effect | Slowly | It absorbs slow |
| 2 | There is positive effect | Comparatively fast | It absorbs fast, moist |
| 3 | There is slight effect | It is relatively slow | It absorbs fast, moist |
| 4 | There is remarkable result | Quickly | It absorbs fast, moist |
Embodiment 1-4's is set as measuring different base oils to dermopathic curative effect situation, and table 1 is the results show that basis
Oil is that SIMMONDSIA CHINENSIS SEED OIL can significantly improve therapeutic effect.
Embodiment 14
The effect of the present embodiment measurement embodiment 4-12 maintenance liquid.
Treatment method: using maintenance liquid of the present invention in the morning, afternoon and evening daily, drips several drops in affected part, uniformly smears, massage a few minutes
Promote to absorb, one week as a treatment course, is used in conjunction 1-4 weeks.
360 rotten foot bifurcation patients are randomly selected, every 40 people is one group, the observation of curative effect after treating.
The above case criterion of therapeutical effect determines are as follows: treats not recur in latter year and is confirmed as rehabilitation；Treating latter year once in a while has gently
Micro- itch is to improve；It is invalid that the state of an illness is unchanged after treatment.
Table 2
It the results are shown in Table 2, oily based on SIMMONDSIA CHINENSIS SEED OIL, Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide, alkannin, tea tree ethereal oil add
Dosage has an impact curative effect, and the effect of embodiment 4,5,12 is more preferable.
Claims (9)
1. a kind of itch-stopping bactericidal maintenance liquid, in parts by weight characterized by comprising
2. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the base oil is selected from the kind from plant
The non-volatile grease extracted in son, flower, rhizome or fruit.
3. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the base oil is selected from SIMMONDSIA CHINENSIS SEED OIL, sweet tea
One or more of apricot kernel oil, grape seed oil, olive oil.
4. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the parts by weight of the alkannin are 0.1~0.2
Part.
5. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the parts by weight of the tea tree ethereal oil are 14~16
Part.
6. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the weight of the Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide
Measuring part is 0.4~0.8 part.
7. itch-stopping bactericidal maintenance liquid as described in claim 1, which is characterized in that the parts by weight of the fat of Oromaius norvaehollandeae are 8~10 parts.
8. the preparation method of described in any item itch-stopping bactericidal maintenance liquid according to claim 1~7 characterized by comprising root
According to formula, alkannin, tea tree ethereal oil, Glycyrrhetic acid 3-O-mono-BETA-D-glucuronide, fat of Oromaius norvaehollandeae are added in base oil, dissolution mixes.
9. the preparation method of itch-stopping bactericidal maintenance liquid according to claim 8, which is characterized in that the temperature of dissolution is 45 DEG C
~50 DEG C.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112608800A (en) * | 2020-12-17 | 2021-04-06 | 江苏耐雀生物工程技术有限公司 | Handmade soap with anti-allergy function and preparation method thereof |
| CN114392263A (en) * | 2021-12-20 | 2022-04-26 | 亿利耐雀生物科技有限公司 | Glycyrrhiza neoside hair loss prevention and hair growth promotion composition and preparation method thereof |
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| CN107411987A (en) * | 2017-05-25 | 2017-12-01 | 江苏耐雀生物工程技术有限公司 | A kind of clear acne compound essential oil of face and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112608800A (en) * | 2020-12-17 | 2021-04-06 | 江苏耐雀生物工程技术有限公司 | Handmade soap with anti-allergy function and preparation method thereof |
| CN114392263A (en) * | 2021-12-20 | 2022-04-26 | 亿利耐雀生物科技有限公司 | Glycyrrhiza neoside hair loss prevention and hair growth promotion composition and preparation method thereof |
| CN114392263B (en) * | 2021-12-20 | 2023-11-14 | 亿利耐雀生物科技有限公司 | Liquiritigenin hair-loss preventing and hair-growing composition and preparation method thereof |
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Application publication date: 20190416 |