CN109612770A - A kind of sampling device of histopathology sample - Google Patents

A kind of sampling device of histopathology sample Download PDF

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Publication number
CN109612770A
CN109612770A CN201910138982.3A CN201910138982A CN109612770A CN 109612770 A CN109612770 A CN 109612770A CN 201910138982 A CN201910138982 A CN 201910138982A CN 109612770 A CN109612770 A CN 109612770A
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CN
China
Prior art keywords
needle tubing
piston rod
card slot
sample
placement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910138982.3A
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Chinese (zh)
Inventor
周斌
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First Affiliated Hospital of Suzhou University
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First Affiliated Hospital of Suzhou University
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Filing date
Publication date
Application filed by First Affiliated Hospital of Suzhou University filed Critical First Affiliated Hospital of Suzhou University
Priority to CN201910138982.3A priority Critical patent/CN109612770A/en
Publication of CN109612770A publication Critical patent/CN109612770A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a kind of sampling devices of histopathology sample, including support construction, for dispose specimen samples sliding installing structure, for the vertically lifting structure of stable lifting, control lifting structure driving mechanism and for the sampling mechanism of collect specimen, the sampling mechanism includes the needle tubing of the piston rod being fixed below driving mechanism and the piston rod periphery that is slidably located in, and the needle tubing is driven by elevating mechanism and gone up and down.Needle tubing of the present invention deepens continuously into histopathology sample, and needle tubing and piston rod cooperation constantly sucking sample can also be observed to control the length of sample acquisition in real time by the scale on needle tubing, be drawn materials so more convenient so as to complete to acquire;And two groups of staggered clamping position-limit mechanisms grip histopathology sample automatically, such design is convenient for when in use putting histopathology sample, the automatic effect for carrying out centralized positioning can be obtained, the sampling of multiple groups part is thus easily facilitated, it is more convenient to use.

Description

A kind of sampling device of histopathology sample
Technical field
The present invention relates to the field of medical instrument technology, the sampling device of specifically a kind of histopathology sample.
Background technique
The materials of histopathology sample (hereinafter referred to as sample), refer to acquired in the tissue of monolith or bulk it is representational Part production pathological section, is used for histopathogenic diagnosis, is a very important link in histopathogenic diagnosis.For big Can the histopathology sample of block collect the diagnosis extremely pass that representational diseased region is presented to diagnostician for disease It is important.Currently used conventional method is first to fix the sample of bulk with neutral formalin, and the set time usually requires 24- 72 hours, it is adjusted that (the processing time of entire sample is generally in 3-5 work according to factors such as the sizes, quality, temperature of sample Make day, it is seen that the length of set time is very important to the influence the time required to completing pathological diagnosis), sample is bigger, fills Divide the fixed required time longer.After sufficiently fixing, there may be the part of diagnostic value for making by pathologist acquisition Make pathological section.If not collecting the tissue of diagnostic value for the first time, need to carry out second or even third time acquisition group It knits, the selection at this acquisition position has apparent empirical and subjectivity.
In the prior art, the materials of pathological tissue specimen be typically all be sliced materials, and sample inside materials simply by Common extruding materials, not only larger to pathological tissue specimen destruction, the sample of materials also has different degrees of damage;And it is normal Rule draw sampling using needle tubing, are suitable only for the sample of fluidised form, because needle tubing is generally fixed, gelatinous pathological tissue Sample is then difficult to completely sample.
Summary of the invention
The purpose of the present invention is to provide a kind of sampling devices of histopathology sample, to solve to mention in above-mentioned background technique Out the problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of sampling device of histopathology sample, including support construction, for disposing the sliding of specimen samples to dispose knot Structure, for the vertically lifting structure of stable lifting, control lifting structure driving mechanism and for the sampler of collect specimen Structure, the sampling mechanism include the needle tubing of the piston rod being fixed below driving mechanism and the piston rod periphery that is slidably located in, The needle tubing is driven by elevating mechanism and is gone up and down.
Further, the support construction passes through a pair of of strut by bottom plate disposed in parallel and partition and symmetrically connects, described Through through hole is connected in the middle part of partition, partition upper end two sides, which are symmetrically embedded in, is provided with rolling bearing, the lifting Mechanism is connected by rolling bearing with the partition;The sliding installing structure, which is slidably connected, to be arranged on the strut.
Further, the sliding installing structure includes the be slidably located in slip ring and two sides slip ring of strut periphery Between parcel shelf connected horizontally, the parcel shelf upper center, which is fixedly connected, is provided with placement card slot, the placement card slot and It is described identical by pore size and be oppositely arranged;The slip ring side is provided with end and institute by being threadedly engaged flexible connection State the locking knob of strut side activity fitting.
Further, the elevating mechanism includes being rotatablely connected the threaded support bar being arranged on the rolling bearing, leading to It crosses and is threadedly engaged the screwed ring for being set in threaded support bar periphery and lifter plate in the screwed ring is arranged in connection, it is described Screwed ring be symmetricly set on two sides threaded support bar periphery, the lifter plate horizontal connection be arranged in two sides screwed ring it Between, the threaded support bar upper end is connected with driving mechanism.
Further, the driving mechanism includes upper cover, sprocket wheel and driving chain, and the upper cover lower end passes through bearing and spiral shell The peripherally pivoted connection of line support rod;The sprocket wheel, which is arranged, is fixed on the threaded support bar periphery, the sprocket wrap of two sides Mating connection is provided with driving chain;The threaded support bar upper end of side, which is also fixedly connected, is provided with control handle, the control Knob is located above the upper cover.
Further, the sampling structure includes being fixed on the piston rod of driving structure lower end and being set under piston rod Hold the needle tubing of periphery, the needle tubing and piston rod is mating is provided with multiple groups, the needle tubing and the corresponding setting of through hole, institute It states needle tubing connection to be arranged on elevating mechanism, the needle tubing is the tapered hollow glass structure of side end pack, the needle Pipe surface has scale, and the piston-rod lower end has and the piston of cannula slides cooperation.
Further, further include in the placement card slot two groups it is opposite be in 90 ° of clamping position-limit mechanisms being staggered, two groups The clamping position-limit mechanism is divided into height different in the placement card slot;The clamping position-limit mechanism includes two symmetrical sliding The dynamic limit plate being arranged between the placement card slot side wall and sliding block through the limit plate and both ends and the placement The connected sliding placement pole of groove sidewall;The limit bullet that the limit plate of two sides is connected by one end with the placement card slot side wall Spring is resiliently arranged in middle part in the placement card slot, and the sliding placement pole, which symmetrically runs through, to be arranged in the limit plate two sides.
Compared with prior art, the beneficial effects of the present invention are: being able to drive threaded support bar by rotating control handle Rotation, so that the threaded support bar of two sides can cooperatively form synchronous fortune with the sprocket wheel chain that driving chain is formed by sprocket wheel Dynamic, when threaded support bar rotation, screwed ring can form up and down motion and being threadedly engaged in threaded support bar periphery Effect moves up and down so that lifter plate is horizontal therewith, and sample is passed through the lifting moving of parcel shelf to needle first when in use Below pipe, needle tubing is driven to decline by controlling the lifting of lifter plate, needle tubing opposing pistons bar declines, and it is negative to form vacuum in needle tubing Pressure, needle tubing deepen continuously into histopathology sample, and needle tubing and piston rod cooperation constantly sucking sample, so as to complete Acquisition can also be observed to control the length of sample acquisition in real time by the scale on needle tubing, be drawn materials so more convenient; And two groups of staggered clamping position-limit mechanisms grip histopathology sample automatically, such design is convenient for when in use by tissue When Pathologic specimen is put, the automatic effect for carrying out centralized positioning can be obtained, the sampling of multiple groups part is thus easily facilitated, using more Add conveniently.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the sampling device of histopathology sample.
Fig. 2 is the structural schematic diagram of partition in a kind of sampling device of histopathology sample.
Fig. 3 is the structural schematic diagram of driving mechanism in a kind of sampling device of histopathology sample.
Fig. 4 is the structural schematic diagram of A-A in a kind of sampling device of histopathology sample.
Fig. 5 is the structural schematic diagram that card slot is disposed in a kind of sampling device of histopathology sample.
In figure: 1- bottom plate, 2- strut, 3- slip ring, 4- locking knob, 5- parcel shelf, 6- dispose card slot, 61- sliding peace Set bar, 62- limit plate, 63- limit spring, 7- partition, 8- through hole, 9- rolling bearing, 10- threaded support bar, 11- screw thread Ring, 12- lifter plate, 13- upper cover, 14- sprocket wheel, 15- driving chain, 16- control handle, 17- needle tubing, 18- piston rod.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
Please refer to Fig. 1~4, in the embodiment of the present invention, a kind of sampling device of histopathology sample, including support construction, For disposing the sliding installing structure of specimen samples, for the driving of the vertically lifting structure of stable lifting, control lifting structure Mechanism and sampling mechanism for collect specimen, the sampling mechanism include be fixed on piston rod 18 below driving mechanism with And the needle tubing 17 for 18 periphery of piston rod that is slidably located in, the needle tubing 17 are driven by elevating mechanism and are gone up and down.
The support construction passes through a pair of of strut 2 by bottom plate 1 disposed in parallel and partition 7 and symmetrically connects, in the partition 7 Portion is through through hole 8 is connected with, and the 7 upper end two sides of partition, which are symmetrically embedded in, is provided with rolling bearing 9, the elevating mechanism It is connected by rolling bearing 9 with the partition 7;The sliding installing structure, which is slidably connected, to be arranged on the strut 2.
The sliding installing structure includes the water between the slip ring 3 and two sides slip ring 3 of 2 periphery of strut that is slidably located in The parcel shelf 5 of flushconnection, 5 upper center of parcel shelf, which is fixedly connected, is provided with placement card slot 6, the placement card slot 6 and institute It is identical and be oppositely arranged to state 8 size of through hole;3 side of slip ring is provided with end and institute by being threadedly engaged flexible connection State the locking knob 4 of 2 side activity of strut fitting.Placement card slot 6 on can dispose histopathology sample for acquire sampling.
The elevating mechanism includes being rotatablely connected the threaded support bar 10 being arranged on the rolling bearing 9, passing through screw thread The lifter plate 12 that cooperation is set in the screwed ring 11 of 10 periphery of threaded support bar and connection is arranged in the screwed ring 11, institute 10 periphery of threaded support bar that screwed ring 11 is symmetricly set on two sides is stated, the spiral shell of two sides is arranged in 12 horizontal connection of lifter plate Between line ring 11,10 upper end of threaded support bar is connected with driving mechanism.When threaded support bar 10 rotates, screwed ring 11 can form the effect of up and down motion in 10 periphery of threaded support bar and being threadedly engaged, so that lifter plate 12 is horizontal therewith Move up and down.
The driving mechanism includes upper cover 13, sprocket wheel 14 and driving chain 15, and 13 lower end of upper cover passes through bearing and spiral shell The peripherally pivoted connection of line support rod 10;The sprocket wheel 14, which is arranged, is fixed on 10 periphery of threaded support bar, the chain of two sides 14 periphery of wheel, which is cooperatively connected, is provided with driving chain 15;10 upper end of threaded support bar of side, which is also fixedly connected, is provided with control rotation Button 16, the control handle 16 are located at 13 top of upper cover.Threaded support bar 10 is able to drive by rotating control handle 16 Rotation, so that the threaded support bar 10 of two sides can be cooperatively formed together by the sprocket wheel chain that sprocket wheel 14 and driving chain 15 are formed Step movement, so that lifter plate 12 be driven to carry out horizontal lifting.
The sampling structure includes being fixed on the piston rod 18 of driving structure lower end and being set in outside 18 lower end of piston rod The needle tubing 17 enclosed, the needle tubing 17 and piston rod 18 is mating is provided with multiple groups, the needle tubing 17 and through hole 8 is corresponding sets It sets, the connection of needle tubing 17 is arranged on adding elevating mechanism, and the needle tubing 17 is the tapered hollow glass of side end pack Structure, 17 surface of needle tubing have scale, the piston that 18 lower end of piston rod has and the needle tubing 17 is slidably matched.
Below the lifting moving to needle tubing 17 that sample can be passed through parcel shelf 5 first when in use by such design, lead to The lifting of control lifter plate 12 is crossed to drive needle tubing 17 to decline, the decline of 17 opposing pistons bar 18 of needle tubing, needle tubing 17 is interior to form vacuum Negative pressure, needle tubing 17 deepen continuously into histopathology sample, and needle tubing 17 and piston rod 18 cooperate constantly sucking sample, thus It can complete to acquire, can also be observed in real time by the scale on needle tubing 17 to control the length of sample acquisition.
Embodiment 2
Referring to Fig. 5, in the embodiment of the present invention, a kind of sampling device of histopathology sample, on the basis of embodiment 1 On, further include two groups in the placement card slot 6 with respect to being in 90 ° of clamping position-limit mechanisms being staggered, limit is clamped described in two groups Branch construction height different in the placement card slot 6;The clamping position-limit mechanism includes two and is symmetrically slidably arranged in institute It states the limit plate 62 between placement 6 side wall of card slot and slides through the limit plate 62 and both ends and 6 side of placement card slot The connected sliding placement pole 61 of wall;The limit that the limit plate 62 of two sides is connected by one end with placement 6 side wall of card slot Spring 63 is resiliently arranged in middle part in the placement card slot 6, and the sliding placement pole 61 is symmetrically through setting in the limit plate 62 two sides.
When such design is convenient for when in use putting histopathology sample, automatic progress centralized positioning can be obtained Effect thus easily facilitates the sampling of multiple groups part, more convenient to use.
The working principle of the invention is: the rotation of threaded support bar 10 is able to drive by rotating control handle 16, thus two The threaded support bar 10 of side can be cooperatively formed by the sprocket wheel chain that sprocket wheel 14 and driving chain 15 are formed and be moved synchronously, and spiral shell is worked as When line support rod 10 rotates, screwed ring 11 can form the effect of up and down motion in 10 periphery of threaded support bar and being threadedly engaged Fruit moves up and down so that lifter plate 12 is horizontal therewith, and sample is passed through the lifting moving of parcel shelf 5 to needle first when in use 17 lower section of pipe, drives needle tubing 17 to decline by controlling the lifting of lifter plate 12, the decline of 17 opposing pistons bar 18 of needle tubing, needle tubing 17 Interior formation negative pressure of vacuum, needle tubing 17 deepen continuously into histopathology sample, and needle tubing 17 and piston rod 18 cooperate continuous suction Enter sample, so as to complete to acquire, can also be observed in real time by the scale on needle tubing 17 to control sample acquisition Length is drawn materials more convenient in this way;And two groups of staggered clamping position-limit mechanisms grip histopathology sample automatically, it is such Design is convenient for that when in use putting histopathology sample, can obtain the automatic effect for carrying out centralized positioning, thus more Add and is sampled convenient for multiple groups part, it is more convenient to use.
The standardized element that the present invention uses can commercially, and shaped piece is according to specification and attached drawing note Load can carry out customized, and the specific connection type of each part is all made of in the prior art mature bolt, rivet, welding etc. Conventional means, mechanical, part and equipment are all made of in the prior art, conventional model, in addition circuit connection uses the prior art Middle conventional connection type, this will not be detailed here.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (7)

1. a kind of sampling device of histopathology sample, sliding installing structure including support construction, for disposing specimen samples, For the vertically lifting structure of stable lifting, control the driving mechanism of lifting structure and for the sampling mechanism of collect specimen, It is characterized in that, the sampling mechanism includes piston rod (18) and the piston rod that is slidably located in being fixed below driving mechanism (18) peripheral needle tubing (17), the needle tubing (17) are driven by elevating mechanism and are gone up and down.
2. a kind of sampling device of histopathology sample according to claim 1, which is characterized in that the support construction by Bottom plate (1) disposed in parallel and partition (7) pass through a pair of of strut (2) and symmetrically connect, through connection setting in the middle part of the partition (7) Have through hole (8), partition (7) the upper end two sides, which are symmetrically embedded in, is provided with rolling bearing (9), and the elevating mechanism passes through rotation Bearing (9) is connected with the partition (7);The sliding installing structure, which is slidably connected, to be arranged on the strut (2).
3. a kind of sampling device of histopathology sample according to claim 2, which is characterized in that the sliding placement knot Structure includes the parcel shelf connected horizontally between the slip ring (3) and two sides slip ring (3) of strut (2) periphery that is slidably located in (5), parcel shelf (5) upper center, which is fixedly connected, is provided with placement card slot (6), the placement card slot (6) and described passes through Hole (8) size is identical and is oppositely arranged;Slip ring (3) side by be threadedly engaged flexible connection be provided with end with it is described The locking knob (4) of strut (2) side activity fitting.
4. a kind of sampling device of histopathology sample according to claim 3, which is characterized in that the placement card slot It (6) further include two groups in respect to being in 90 ° of clamping position-limit mechanisms being staggered, clamping position-limit mechanism described in two groups is divided into described Dispose height different in card slot (6);The clamping position-limit mechanism includes two and is symmetrically slidably arranged in the placement card slot (6) Limit plate (62) and sliding between side wall run through the limit plate (62) and both ends are connected with placement card slot (6) side wall Sliding placement pole (61);The limit that the limit plate (62) of two sides is connected by one end with described placement card slot (6) side wall Spring (63) is resiliently arranged in middle part in the placement card slot (6), and the sliding placement pole (61) is symmetrically through setting described Limit plate (62) two sides.
5. a kind of sampling device of histopathology sample according to claim 1, which is characterized in that the elevating mechanism packet It includes and is rotatablely connected the threaded support bar (10) being arranged on the rolling bearing (9), be set in threaded support by being threadedly engaged The lifter plate (12) that the screwed ring (11) of bar (10) periphery and connection are arranged on the screwed ring (11), the screwed ring (11) it is symmetricly set on threaded support bar (10) periphery of two sides, the screw thread of two sides is arranged in lifter plate (12) horizontal connection Between ring (11), threaded support bar (10) upper end is connected with driving mechanism.
6. a kind of sampling device of histopathology sample according to claim 5, which is characterized in that the driving mechanism packet Upper cover (13), sprocket wheel (14) and driving chain (15) are included, upper cover (13) lower end passes through bearing and threaded support bar (10) outside Enclose rotation connection;The sprocket wheel (14), which is arranged, is fixed on the threaded support bar (10) periphery, and the sprocket wheel (14) of two sides is outside It encloses mating connection and is provided with driving chain (15);Threaded support bar (10) upper end of side, which is also fixedly connected, is provided with control handle (16), the control handle (16) is located above the upper cover (13).
7. the sampling device of any a kind of histopathology sample according to claim 1~6, which is characterized in that described to take Spline structure includes the piston rod (18) for being fixed on driving structure lower end and the needle tubing for being set in piston rod (18) lower end periphery (17), the needle tubing (17) and the piston rod (18) is mating is provided with multiple groups, the needle tubing (17) and through hole (8) are corresponding Setting, the needle tubing (17) connection are arranged on elevating mechanism, and the needle tubing (17) is tapered hollow of side end pack Glass structure, needle tubing (17) surface have scale, and piston rod (18) lower end has and the needle tubing (17) sliding is matched The piston of conjunction.
CN201910138982.3A 2019-02-25 2019-02-25 A kind of sampling device of histopathology sample Pending CN109612770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910138982.3A CN109612770A (en) 2019-02-25 2019-02-25 A kind of sampling device of histopathology sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910138982.3A CN109612770A (en) 2019-02-25 2019-02-25 A kind of sampling device of histopathology sample

Publications (1)

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CN109612770A true CN109612770A (en) 2019-04-12

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110658047A (en) * 2019-11-12 2020-01-07 宁夏医科大学 Animal experiment pathological specimen fixing, dehydrating and decalcifying system and method
CN111122284A (en) * 2020-01-20 2020-05-08 兰州大学 Wax device is gone into in assistance of pathology sample

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110658047A (en) * 2019-11-12 2020-01-07 宁夏医科大学 Animal experiment pathological specimen fixing, dehydrating and decalcifying system and method
CN110658047B (en) * 2019-11-12 2024-02-06 宁夏医科大学 Animal experiment pathology specimen fixing, dehydrating and decalcification system and method
CN111122284A (en) * 2020-01-20 2020-05-08 兰州大学 Wax device is gone into in assistance of pathology sample
CN111122284B (en) * 2020-01-20 2020-12-29 兰州大学 Wax device is gone into in assistance of pathology sample

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Inventor after: Zhou Bin

Inventor after: Chen Weichang

Inventor after: Wu Hongya

Inventor after: Zhang Guangbo

Inventor after: Zhang Xueguang

Inventor before: Zhou Bin

CB03 Change of inventor or designer information
RJ01 Rejection of invention patent application after publication

Application publication date: 20190412

RJ01 Rejection of invention patent application after publication