CN109602663A - A kind of content in freckle cream and preparation method thereof - Google Patents
A kind of content in freckle cream and preparation method thereof Download PDFInfo
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- CN109602663A CN109602663A CN201910098122.1A CN201910098122A CN109602663A CN 109602663 A CN109602663 A CN 109602663A CN 201910098122 A CN201910098122 A CN 201910098122A CN 109602663 A CN109602663 A CN 109602663A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The present invention relates to a kind of content in freckle cream and preparation method thereof, the raw material components of the content in freckle cream include: glycerol 4-8 parts by weight, propylene glycol 1.5-5 parts by weight, dormant oil 1-5 parts by weight, caprylic/capric triglyceride 4-8 parts by weight, alpha-arbutin 0.5-1.5 parts by weight, niacinamide 0.2-0.8 parts by weight, cetostearyl alcohol 1-3 parts by weight, the smooth stearate 0.2-0.6 parts by weight of sorb, stearine 0.5-1.5 parts by weight, PEG-100 stearate 1-2 parts by weight, isohexadecane 3-6 parts by weight, sodium acrylate/sodium acryloyldimethyl taurate copolymers 1-1.8 parts by weight, glycine betaine 2-4 parts by weight, tocopherol 0.1-0.3 parts by weight, Sodium Hyaluronate 0.02-0.1 parts by weight, preservative 0.0 5-0.07 parts by weight, water 53-80 parts by weight.Reasonable recipe of the present invention, freckle effect are significant and safe and non-stimulating.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of content in freckle cream and preparation method thereof.
Background technique
Color spot refers to spot different with ambient color, including freckle, blackspot, chloasma and senile plaque etc..It is due to skin
The increase of skin melanin and the common face of one kind that is formed is brown or the dyschromicum skin of melanin pigmentation, damage capacitive
Disease is mainly in cheek and forehead position, aggravates after solarization.
The Biochemical processes that melanin is formed, are tyrosine under the action of the tyrosinase of copper ion containing high price, oxidation
It generates 3,4-dihydroxyphenyl-L-alanine (DOPA), then DOPA quinone is oxidized to by tyrosinase, be further oxidized to 5,6- dihydroxy
Indoles generates melanin after polymerization.Therefore, inhibiting the generation of melanin can be realized by following approach: (1) directly inhibiting black
A variety of rate-limiting enzymes in pigment generating process, the activity including tyrosinase, dopachrome interconvertible enzyme；(2) it is thin to destroy melanin
Born of the same parents inhibit the formation of melanin granule；(3) DOPA quinone is restored, i.e., by the reduction to melanin intermediates, hinders junket ammonia
Acid arrives melanin process.It in addition, the formation of melanin is not only the behavior intracellular of melanocyte, while being also that extracellular substance is made
As a result, such as Endothelin, is that melanin forms signaling molecule important in signal transduction path.In addition there are also ultraviolet light because
Element also will affect the generation etc. of melanin.
Current Freckle removing cosmetics, which are substantially, forms middle tyrosine rate-limiting enzyme by effect melanin to influence black
The generation of element, action site is single, and effect is also not fully up to expectations.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the present invention provides a kind of content in freckle cream and preparation method thereof, institute
Stating content in freckle cream can act on reaction chain in melanin forming process on multiple sites, thus have the function that effective nti-freckle,
Freckle effect is substantially better than existing product.
The technical solution of the present invention is as follows:
A kind of content in freckle cream, raw material components include:
Glycerol 4-8 parts by weight, propylene glycol 1.5-5 parts by weight, dormant oil 1-5 parts by weight, caprylic/capric triglyceride 4-8 weight
Measure part, alpha-arbutin 0.5-1.5 parts by weight, niacinamide 0.2-0.8 parts by weight, cetostearyl alcohol 1-3 parts by weight, the smooth tristearin of sorb
Acid esters 0.2-0.6 parts by weight, stearine 0.5-1.5 parts by weight, PEG-100 stearate 1-2 parts by weight, isohexadecane
3-6 parts by weight, sodium acrylate/sodium acryloyldimethyl taurate copolymers 1-1.8 parts by weight, glycine betaine 2-4 parts by weight, fertility
Phenol 0.1-0.3 parts by weight, Sodium Hyaluronate 0.02-0.1 parts by weight, preservative 0.05-0.07 parts by weight, water 53-80 parts by weight.
Further, the raw material components of the content in freckle cream include:
6 parts by weight of glycerol, 3 parts by weight of propylene glycol, 3 parts by weight of dormant oil, 6 parts by weight of caprylic/capric triglyceride, α-black bearberry
Smooth 0.5 parts by weight of stearate of 1 parts by weight of glycosides, 0.5 parts by weight of niacinamide, 2 parts by weight of cetostearyl alcohol, sorb, glyceryl stearate
1 parts by weight of acid esters, 1.5 parts by weight of PEG-100 stearate, 5 parts by weight of isohexadecane, sodium acrylate/acryloyldimethyl ox
1.5 parts by weight of sodium sulfonate copolymers, 3 parts by weight of glycine betaine, 0.2 parts by weight of tocopherol, 0.06 parts by weight of Sodium Hyaluronate, anti-corrosion
0.06 parts by weight of agent, 66 parts by weight of water.
The preparation method of the content in freckle cream, includes the following steps:
(1) it will stir and be warming up to 80-90 DEG C, obtain after water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate mix
Water phase；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine,
After PEG-100 stearate, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stir
It mixes and is warming up to 80-90 DEG C, obtain oily phase；
(3) under vacuum, the oil is added to the water phase, homogeneous obtains milk；
(4) milk is cooled to 40 DEG C hereinafter, then sequentially add alpha-arbutin, niacinamide, preservative, stirred
Uniformly to get the content in freckle cream.
Further, raw material components further include the snake mother-in-law of the ginkgo biloba extract of 0.5-1.5 parts by weight, 0.5-1.5 parts by weight
The Baical Skullcap root P.E of seed extract, the camomile extract of 0.5-1.5 parts by weight and 0.5-1.5 parts by weight.
The preparation method of the content in freckle cream, includes the following steps:
(1) it will stir and be warming up to 80-90 DEG C, obtain after water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate mix
Water phase；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine,
After PEG-100 stearate, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stir
It mixes and is warming up to 80-90 DEG C, obtain oily phase；
(3) under vacuum, the oil is added to the water phase, homogeneous obtains milk；
(4) by the milk be cooled to 40 DEG C hereinafter, then sequentially add alpha-arbutin, niacinamide, ginkgo biloba extract,
Waltheria indica extract, camomile extract, Baical Skullcap root P.E, preservative stir evenly to get the content in freckle cream.
Further, the preservative is the mixture of methyl hydroxybenzoate and Bis(hydroxymethyl)imidazolidinyl urea.
Further, in the water phase preparation, 85 DEG C are warming up to described in progress.
Further, during the oil is mutually prepared, 80 DEG C are warming up to described in progress.
Further, in step (3), the speed of the homogeneous is 3000-4000rpm, and the time of the homogeneous is 4-
6min。
Further, after the homogeneous, then with the revolving speed stirring 10-20min of 10-15rpm.
The invention has the benefit that
Content in freckle cream of the present invention, contains alpha-arbutin and niacinamide, wherein alpha-arbutin be extracted form natural plant at
Point, have the function of inhibiting tyrosinase activity, the melanosome that niacinamide can lower melanocyte to keratinocyte turns
Fortune to influence the calmness of melanin on the skin, while interfering the cell signal between melanocyte and keratinocyte logical
Road reduces the generation of melanin, uses simultaneously with alpha-arbutin, freckle effect can be enhanced.
Further, the raw material components of content in freckle cream of the present invention further include ginkgo biloba extract, waltheria indica extract, ocean it is sweet
Chrysanthemum extract and Baical Skullcap root P.E, the discovery this is because, present invention applicant is studied for a long period of time, ginkgo biloba extract, waltheria indica
Extract and Baical Skullcap root P.E are applied in combination, and can inhibit the activity of dopachrome interconvertible enzyme to a certain extent, and chamomile
Contain endothelin antagonist in extract, can weaken melanocyte formed in indispensable signal transduction process.This hair
It is bright to can act on anti-on multiple sites in melanin forming process from the source that color spot is formed by reasonable formula
Chain is answered, to have the function that effective nti-freckle, freckle effect is substantially better than existing product.Present component is natural, and safety is stingless
Swash, has both moisture-keeping function, be the ideal chose of color spot personage's skin care.
Specific embodiment
Below by specific embodiment, the invention will be further described.
1g is represented in following embodiment with 1 parts by weight.
Embodiment 1
The present embodiment provides a kind of content in freckle cream, raw material components include:
4 parts by weight of glycerol, 1.5 parts by weight of propylene glycol, 1 parts by weight of dormant oil, 4 parts by weight of caprylic/capric triglyceride, α-bear
Smooth 0.2 parts by weight of stearate of 0.5 parts by weight of fruit glycosides, 0.2 parts by weight of niacinamide, 1 parts by weight of cetostearyl alcohol, sorb, glycerol
0.5 parts by weight of stearate, 1 parts by weight of PEG-100 stearate, 3 parts by weight of isohexadecane, sodium acrylate/acryloyl diformazan
1 parts by weight of base Taurate Copolymer, 2 parts by weight of glycine betaine, 0.1 parts by weight of tocopherol, 0.02 parts by weight of Sodium Hyaluronate, water
80 parts by weight, 0.01 parts by weight of methyl hydroxybenzoate, 0.05 parts by weight of Bis(hydroxymethyl)imidazolidinyl urea, 0.001 parts by weight of essence,
0.0001 parts by weight of toner (CI 19140), 0.5 parts by weight of ginkgo biloba extract, 0.5 parts by weight of waltheria indica extract, chamomile mention
Take 0.5 parts by weight of object, 0.5 parts by weight of Baical Skullcap root P.E.
Further, a kind of method preparing the content in freckle cream is provided, is included the following steps:
(1) it after mixing water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate, methyl hydroxybenzoate, stirs and is warming up to 80
DEG C, obtain water phase；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine,
After PEG-100 stearate, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stir
It mixes and is warming up to 80 DEG C, obtain oily phase；
(3) under vacuum, the oil is added to the water phase, with the revolving speed homogeneous 6min of 3000rpm, then with 10rpm
Revolving speed stir 20min, obtain milk；
(4) milk is cooled to 40 DEG C, then sequentially adds alpha-arbutin, niacinamide, ginkgo biloba extract, snake mother-in-law
Seed extract, camomile extract, Baical Skullcap root P.E, Bis(hydroxymethyl)imidazolidinyl urea, stir evenly, and filtering obtains nti-freckle
White semi-finished product, after the content in freckle cream semi-finished product are stood, through detection, filling, packaging to get the content in freckle cream finished product.
Embodiment 2
The present embodiment provides a kind of content in freckle cream, raw material components include:
8 parts by weight of glycerol, 5 parts by weight of propylene glycol, 5 parts by weight of dormant oil, 8 parts by weight of caprylic/capric triglyceride, α-black bearberry
Smooth 0.6 parts by weight of stearate of 1.5 parts by weight of glycosides, 0.8 parts by weight of niacinamide, 3 parts by weight of cetostearyl alcohol, sorb, glycerol are hard
1.5 parts by weight of resin acid ester, 2 parts by weight of PEG-100 stearate, 6 parts by weight of isohexadecane, sodium acrylate/acryloyldimethyl
1.8 parts by weight of Taurate Copolymer, 4 parts by weight of glycine betaine, 0.3 parts by weight of tocopherol, 0.1 parts by weight of Sodium Hyaluronate, water
53 parts by weight, 0.01 parts by weight of methyl hydroxybenzoate, 0.05 parts by weight of Bis(hydroxymethyl)imidazolidinyl urea, 0.001 parts by weight of essence,
0.0001 parts by weight of toner (CI 19140), 1.5 parts by weight of ginkgo biloba extract, 1.5 parts by weight of waltheria indica extract, chamomile mention
Take 1.5 parts by weight of object, 1.5 parts by weight of Baical Skullcap root P.E.
Further, a kind of method preparing the content in freckle cream is provided, is included the following steps:
(1) it after mixing water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate, methyl hydroxybenzoate, stirs and is warming up to 90
DEG C, obtain water phase；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine,
After PEG-100 stearate, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stir
It mixes and is warming up to 90 DEG C, obtain oily phase；
(3) under vacuum, the oil is added to the water phase, with the revolving speed homogeneous 4min of 4000rpm, then with 15rpm
Revolving speed stir 10min, obtain milk；
(4) milk is cooled to 35 DEG C, then sequentially adds alpha-arbutin, niacinamide, ginkgo biloba extract, snake mother-in-law
Seed extract, camomile extract, Baical Skullcap root P.E, Bis(hydroxymethyl)imidazolidinyl urea, stir evenly, and filtering obtains nti-freckle
White semi-finished product, after the content in freckle cream semi-finished product are stood, through detection, filling, packaging to get the content in freckle cream finished product.
Embodiment 3
The present embodiment provides a kind of content in freckle cream, raw material components include:
6 parts by weight of glycerol, 3 parts by weight of propylene glycol, 3 parts by weight of dormant oil, 6 parts by weight of caprylic/capric triglyceride, α-black bearberry
Smooth 0.5 parts by weight of stearate of 1 parts by weight of glycosides, 0.5 parts by weight of niacinamide, 2 parts by weight of cetostearyl alcohol, sorb, glyceryl stearate
1 parts by weight of acid esters, 1.5 parts by weight of PEG-100 stearate, 5 parts by weight of isohexadecane, sodium acrylate/acryloyldimethyl ox
1.5 parts by weight of sodium sulfonate copolymers, 3 parts by weight of glycine betaine, 0.2 parts by weight of tocopherol, 0.06 parts by weight of Sodium Hyaluronate, water 66
Parts by weight, 0.01 parts by weight of methyl hydroxybenzoate, 0.05 parts by weight of Bis(hydroxymethyl)imidazolidinyl urea, 0.001 parts by weight of essence, coloring
0.0001 parts by weight of agent (CI 19140), 1 parts by weight of ginkgo biloba extract, 1 parts by weight of waltheria indica extract, camomile extract 1
Parts by weight, 1 parts by weight of Baical Skullcap root P.E.
Further, a kind of method preparing the content in freckle cream is provided, is included the following steps:
(1) it after mixing water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate, methyl hydroxybenzoate, stirs and is warming up to 85
DEG C, obtain water phase；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine,
After PEG-100 stearate, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stir
It mixes and is warming up to 80 DEG C, obtain oily phase；
(3) under vacuum, the oil is added to the water phase, with the revolving speed homogeneous 5min of 3500rpm, then with 15rpm
Revolving speed stir 15min, obtain milk；
(4) milk is cooled to 35 DEG C, then sequentially adds alpha-arbutin, niacinamide, ginkgo biloba extract, snake mother-in-law
Seed extract, camomile extract, Baical Skullcap root P.E, Bis(hydroxymethyl)imidazolidinyl urea, stir evenly, and filtering obtains nti-freckle
White semi-finished product, after the content in freckle cream semi-finished product are stood, through detection, filling, packaging to get the content in freckle cream finished product.
Experimental example
1, the content in freckle cream finished product that above-described embodiment 3 is prepared is examined, the method for inspection and concrete outcome
It see the table below 1~4:
1 method of inspection of table
2 organoleptic indicator of table
| Inspection project | Inspection result |
| Color | Yellow |
| Character | Lotion |
| Smell | Slightly characteristic odor |
3 hygienic chemistry index of table
4 microbiological indicator of table
| Inspection project | Inspection result |
| Total plate count | ≤1000CFU/g |
| Yeast and mold sum | ≤100CFU/g |
| Heat-resisting coliform | It is not detected |
| Staphylococcus aureus | It is not detected |
| Pseudomonas aeruginosa | It is not detected |
2, the content in freckle cream being prepared with above-described embodiment 3 has carried out following Efficacy experiments to verify nti-freckle effect of the invention
Fruit.
122 ages are chosen at 30~45 years old, face has different degrees of pigmented experimenter, is randomly divided into test group
And control group, every group of 61 people, the content in freckle cream that test group is prepared using the embodiment of the present invention 3, control group use commercially available nti-freckle
Frost advises and is uniformly applied to face after washing one's face daily morning and evening, is used continuously 3 months, the results are shown in Table 5.
5 freckle effect of table
| Total number of persons | Efficiently individual quantity | Effective number | Invalid number | It is efficient | |
| Test group | 61 | 26 | 23 | 12 | 80.33% |
| Control group | 61 | 29 | 8 | 24 | 60.66% |
The result shows that the freckle effect of content in freckle cream of the present invention is substantially better than commercial product, effective percentage reaches
80.33%, it is the ideal chose of color spot problem crowd.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of content in freckle cream, which is characterized in that raw material components include:
Glycerol 4-8 parts by weight, propylene glycol 1.5-5 parts by weight, dormant oil 1-5 parts by weight, caprylic/capric triglyceride 4-8 parts by weight,
Alpha-arbutin 0.5-1.5 parts by weight, niacinamide 0.2-0.8 parts by weight, cetostearyl alcohol 1-3 parts by weight, the smooth stearate of sorb
0.2-0.6 parts by weight, stearine 0.5-1.5 parts by weight, PEG-100 stearate 1-2 parts by weight, isohexadecane 3-6
Parts by weight, sodium acrylate/sodium acryloyldimethyl taurate copolymers 1-1.8 parts by weight, glycine betaine 2-4 parts by weight, tocopherol
0.1-0.3 parts by weight, Sodium Hyaluronate 0.02-0.1 parts by weight, preservative 0.05-0.07 parts by weight, water 53-80 parts by weight.
2. content in freckle cream according to claim 1, which is characterized in that raw material components include:
6 parts by weight of glycerol, 3 parts by weight of propylene glycol, 3 parts by weight of dormant oil, 6 parts by weight of caprylic/capric triglyceride, alpha-arbutin 1
Smooth 0.5 parts by weight of stearate of parts by weight, 0.5 parts by weight of niacinamide, 2 parts by weight of cetostearyl alcohol, sorb, stearine
1 parts by weight, 1.5 parts by weight of PEG-100 stearate, 5 parts by weight of isohexadecane, sodium acrylate/acryloyldimethyl taurine
Sodium copolymer 1 .5 parts by weight, 3 parts by weight of glycine betaine, 0.2 parts by weight of tocopherol, 0.06 parts by weight of Sodium Hyaluronate, preservative
0.06 parts by weight, 66 parts by weight of water.
3. content in freckle cream according to claim 1, which is characterized in that raw material components further include the ginkgo of 0.5-1.5 parts by weight
Extract, the waltheria indica extract of 0.5-1.5 parts by weight, 0.5-1.5 parts by weight camomile extract and 0.5-1.5 weight
The Baical Skullcap root P.E of part.
4. content in freckle cream according to claim 1, which is characterized in that the preservative includes methyl hydroxybenzoate and bis- (methylols)
Imidazolidinyl urea.
5. the preparation method of content in freckle cream as claimed in claim 1 or 2, which comprises the steps of:
(1) it will stir and be warming up to 80-90 DEG C, and obtain water phase after water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate mix；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine, PEG-
After 100 stearates, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stirring is simultaneously
It is warming up to 80-90 DEG C, obtains oily phase；
(3) under vacuum, the oil is added to the water phase, homogeneous obtains milk；
(4) milk is cooled to 40 DEG C hereinafter, then sequentially adding alpha-arbutin, niacinamide, preservative, stirring is equal
It is even to get the content in freckle cream.
6. the preparation method of content in freckle cream described in claim 3, which comprises the steps of:
(1) it will stir and be warming up to 80-90 DEG C, and obtain water phase after water, glycerol, propylene glycol, glycine betaine, Sodium Hyaluronate mix；
(2) by dormant oil, caprylic/capric triglyceride, cetostearyl alcohol, the smooth stearate of sorb, stearine, PEG-
After 100 stearates, isohexadecane, sodium acrylate/sodium acryloyldimethyl taurate copolymers, tocopherol mixing, stirring is simultaneously
It is warming up to 80-90 DEG C, obtains oily phase；
(3) under vacuum, the oil is added to the water phase, homogeneous obtains milk；
(4) milk is cooled to 40 DEG C hereinafter, then sequentially adding alpha-arbutin, niacinamide, ginkgo biloba extract, snake mother-in-law
Seed extract, camomile extract, Baical Skullcap root P.E, preservative stir evenly to get the content in freckle cream.
7. according to the preparation method of the content in freckle cream of claim 5 or 6, which is characterized in that in the water phase preparation, described in progress
It is warming up to 85 DEG C.
8. according to the preparation method of the content in freckle cream of claim 5 or 6, which is characterized in that during the oil is mutually prepared, described in progress
It is warming up to 80 DEG C.
9. according to the preparation method of the content in freckle cream of claim 5 or 6, which is characterized in that in step (3), the speed of the homogeneous
Degree is 3000-4000rpm, and the time of the homogeneous is 4-6min.
10. according to the preparation method of the content in freckle cream of claim 5 or 6, which is characterized in that after the homogeneous, then with 10-
The revolving speed of 15rpm stirs 10-20min.
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