CN109568124A - A kind of electrode catheter detection device and its application method - Google Patents
A kind of electrode catheter detection device and its application method Download PDFInfo
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- CN109568124A CN109568124A CN201811600508.XA CN201811600508A CN109568124A CN 109568124 A CN109568124 A CN 109568124A CN 201811600508 A CN201811600508 A CN 201811600508A CN 109568124 A CN109568124 A CN 109568124A
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- electrode
- electrode catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/02—Devices for locating such points
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/08—Devices for applying needles to such points, i.e. for acupuncture ; Acupuncture needles or accessories therefor
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- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The invention discloses a kind of electrode catheter detection device and its application methods, described device includes electrode catheter and needle position detection host, it includes main control module that host is detected in the needle position, detection module, man machine operation interface, communication interface, environmental parameter compensating module and data storage center, man machine operation interface, communication interface, environmental parameter compensating module and data storage center arranged in parallel respectively with main control module communication connection, detection module respectively with main control module, electrode catheter communication connection, detection module includes the resistance detection module with electrode catheter and main control module communication connection respectively, susceptance detection module, capacitive detection module and inductance detection module.The insertion position that the present invention is capable of accurate detecting electrode probe promotes effect to be conducive to for electrode catheter being accurately inserted into blood vessel.
Description
Technical field
Medical instruments field of the present invention, specifically a kind of electrode catheter detection device and its application method.
Background technique
The skill of handling needles refers to be pierced into needle set (being often referred to acupuncture needle) according to certain angle under the guidance of theory of traditional Chinese medical science and suffer from present
In person's body, with the twisted mesh for carrying out stimulating to reach treatment disease to human body privileged site with the manipulations of acupuncture such as slotting are proposed
's.It is pierced into point and is known as human acupoint, abbreviation acupuncture point.It is counted according to newest science of acupuncture and moxibustion teaching material, human body shares 361 decent acupuncture points.
Ancient Times in China using acupuncture needle, acupuncture needle treat it is sick and wounded always for a long time, be needle and length from ancient times " nine kinds of needles " according to legend
Needle develops.The traditional Chinese medicine and pharmacy system (theory of traditional Chinese medical science, Chinese pharmacology, the science of acupuncture and moxibustion) that Chinese nation ancestors found, the wherein science of acupuncture and moxibustion
Occupy relatively unique status.Acupuncture analgesia or even treatment pain are exactly widely known so far, wide-spread to all over the world.
But we are to silver needle acupuncture therapy, it have in terms of controlling pain unique late result be it is rarely known by the people, it is only in south
Patrilineal line of descent with only one son in each generation is continued to use in civil doctor.
The silver needle (silver production) used using folklore makees intensive acupuncture therapy, achieves unexpected treatment
Effect.Existing strong analgesic activity, and have pain treating effect at a specified future date.More surprisingly, it is found that all positions through needle thorn produce
The muscle spasmus phenomenon caused by pain that raw lasting muscle relaxation effect, i.e. people are difficult to tackle is released magically.This is
The breakthrough in a curative effect that traditional silver needle acupuncture therapy obtains under Soft tissue surgery theoretical direction.That is,
It is hard to work through general physical therapy and drug therapy, must perform the operation just curable intractable pain through surgical dissolution, use
Intensive silver needle acupuncture treatment can obtain significant curative effect (each diseased region only makees seance).
So far, the treatment method of this " with needle for knife " has been generalized to rapidly the numerous medical institutions in the whole nation.From certain meaning
It is said in justice, silver needle therapy seems the hand-manipulating of needle, still follows " rather losing its cave, do not follow its warp " principle, operation of actually loosening, it has also become
A unique branch in modern acupuncture therapy.Since nineteen seventies, there are about the serious waist-legs of more than 20000 examples
Bitterly, cervicobrachialgia, omarthralgia, knee joint pain patient are used the therapy, are received extremely satisfactorily curative effect, and cure rate is up to 90%
More than.Grams for having added a newcomer, being expected to very much as mankind's difficulty pain in the treatment family of chronic ache illness more
One of star.
The implantation of conventional needle will lean on skilled doctor's handicraft, and accurate dynamics is held, but is also inevitably placed
The problem of position deviation.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of electrode catheter detection devices, being capable of accurate detecting electrode probe
Insertion position promote effect to be conducive to for electrode catheter being accurately inserted into blood vessel.
In order to solve the above-mentioned technical problem, the present invention takes following technical scheme:
A kind of electrode catheter detection device, described device include electrode catheter and needle position detection host, which detects host packet
Main control module, detection module, man machine operation interface, communication interface, environmental parameter compensating module and data storage center are included, it is man-machine
Operation interface, communication interface, environmental parameter compensating module and data storage center arranged in parallel are communicated with main control module respectively to be connected
Connect, detection module respectively with main control module, electrode catheter communication connection.
The detection module includes examining respectively with the resistance detection module of electrode catheter and main control module communication connection, susceptance
Survey module, capacitive detection module and inductance detection module.
The electrode catheter includes reference probe and electrode needle, is led to after the reference probe and electrode needle connection with detection module
News connection, the two poles of the earth of reference probe and electrode needle composition detection.
The reference probe is arranged one group, and electrode needle setting is at least one set of.
The communication interface is fixed network interface, radio network interface or interface of internet of things.
The main control chip of the main control module is single-chip microcontroller, digital information processing system chip DSP or embedded system core
Piece.
A kind of application method of electrode catheter detection device, comprising the following steps:
It is first implanted into reference probe in the arteries or vein blood vessel of affected areas tissue regions, is replanted into electrode needle, benchmark is visited
The two poles of the earth of needle and electrode needle composition detection；
The data information that detection module will test by reference probe and electrode needle feeds back the main control module root into main control module
According to the data in data storage center, the insertion situation of current reference probe and electrode needle is judged, and will be inserted into situation in people
It is displayed for checking in machine operation interface.
After the data information that the detection module will test feeds back to main control module, main control module according to environmental parameter into
Row compensation data, revised data are compared with the data of data storage center, so that judgement obtains reference probe and electricity
The insertion situation of pole needle.
The present invention passes through the position of real-time detection electrode catheter, so as to which electrode catheter is accurately inserted into blood vessel
In, accurate positioning, castering action effect.
Detailed description of the invention
Fig. 1 be in electrode catheter implanting tissue of the embodiment of the present invention with vessel position schematic diagram；
Fig. 2 is electrode catheter needle position of embodiment of the present invention detection control host block diagram；
Fig. 3 is the equivalent circuit diagram of electrode catheter implantable intravascular model of the embodiment of the present invention；
Fig. 4 is that the needle point that the embodiment of the present invention is being implanted into is in tissue location and corresponding resistance value relation schematic diagram；
Fig. 5 is that the needle point that the embodiment of the present invention is being implanted into is in tissue location and corresponding electric conductivity value relation schematic diagram.
Specific embodiment
To further understand the features of the present invention, technological means and specific purposes achieved, function, below with reference to
Present invention is further described in detail with specific embodiment for attached drawing.
As shown in Fig. 1, with vessel position schematic diagram in electrode catheter implanting tissue, 1.: the benchmark in arteries is electric
Pole probe；2.: pass through arterial vascular electrode needle；3.: the electrode needle in arteries；4.: the electrode needle in branch arteries；
5.: it is not inserted into arterial vascular electrode needle；6.: the reference electrode needle in vein blood vessel；7.: it is not inserted into the electrode of vein blood vessel
Needle；8.: the electrode needle in vein blood vessel；9.: the electrode needle in branch vein blood vessel；10.: across the electrode needle of vein blood vessel.
As shown in Fig. 2, present invention discloses a kind of electrode catheter detection devices, including electrode catheter and needle position detection master
Machine, it includes main control module, detection module, man machine operation interface, communication interface, environmental parameter compensating module which, which detects host,
And data storage center, man machine operation interface, communication interface, environmental parameter compensating module and data storage center arranged in parallel point
Not with main control module communication connection, detection module respectively with main control module, electrode catheter communication connection.Electrode catheter includes benchmark
Probe and electrode needle, the reference probe and electrode needle simultaneously connect rear and detection module communication connection, reference probe and electrode needle composition
The two poles of the earth of detection.The settable several groups of electrode needle, each group electrode needle are connected in parallel, convenient for the contact pin demand of different location.Pass through
Man machine operation interface can be inputted and be checked, the operation of staff is facilitated.
The data of data storage center storage have: ethnic group data, gender, age, type blood, blood pressure, pulse, heartbeat frequency
The parameters such as rate, blood parameters, body temperature, data are fitted based on practical experience, form decision system, carry out needle position in conjunction with measured data
Judgement.It is, of course, also possible to store other kinds of data, it will not enumerate herein, enumerating above is not to this programme
It limits.
The detection module includes examining respectively with the resistance detection module of electrode catheter and main control module communication connection, susceptance
Survey module, capacitive detection module and inductance detection module, by multiple and different detection modules, detect respectively tissue inductance and
Susceptance, by between reference electrode probe and electrode needle resistance data and susceptance Data Detection come out and feed back main control module,
Compensation data, revised number are carried out according to environmental parameter (parameters such as temperature, humidity, height above sea level, longitude, latitude, local time)
It is compared according to the data with data storage center, judges whether to enter skin, if implanting tissue, if implantable intravascular is
Various electrode catheters, are accurately implanted in blood vessel by the various states such as no puncture blood vessel.
The communication interface is fixed network interface, radio network interface or interface of internet of things, convenient for straight with external equipment
Communication connection is connect, or is wirelessly connected.
The main control module is the core and data hub transmission for controlling host, in the present embodiment, the master of main control module
Controlling chip can be single-chip microcontroller, digital information processing system chip DSP, embedded system chip etc., specific main control chip model
It can choose according to actual needs, such as existing known products may be selected in the present embodiment: embedded-microcontroller Freescale
High-performance ARM9 processor.
As shown in Fig. 3, the equivalent circuit diagram of electrode catheter implantable intravascular model, is fitted by data, complicated life
Object tissue is equivalent to variable resistance R1, variable inductance L1, connects with variable capacitance C1, and with variable resistance R2, variable inductance
L2, it is in parallel with variable capacitance C3 after concatenated model again.According to measurement R1, L1, C1 and R2, the corresponding ginseng of L2, C2 under different conditions
Number, and it is stored in data center, the reference frame as follow-up test.By by bio-tissue be equivalent to corresponding resistance,
Inductance etc. a, so that model convenient for calculating is set up, as judgment basis.
In addition, present invention further teaches a kind of application methods of electrode catheter detection device, comprising the following steps:
It is first implanted into reference probe in the arteries or vein blood vessel of affected areas tissue regions, is replanted into electrode needle, benchmark is visited
The two poles of the earth of needle and electrode needle composition detection, can detected susceptance, the resistance data between reference probe and electrode needle.
The data information that detection module will test by reference probe and electrode needle feeds back the master control mould into main control module
Root tuber judges the insertion situation of current reference probe and electrode needle according to the data in data storage center, and will be inserted into situation
It is displayed for checking in man machine operation interface.
Specific operation:
As shown in Fig. 4, the needle point being implanted into is in tissue location and corresponding resistance value relation schematic diagram, reference electrode probe
In implantable intravascular, each position data of another electrode catheter tissue, data 1 ~ 10 be electrode catheter be implanted into skin, by shallowly to
Deep resistance change is successively decreased variation by 350000 Ω to 240000 Ω respectively；Data 11 ~ 20 are electrode catheter implantation fat,
Resistance change from shallow to deep is changed by 200000 Ω to 10000 Ω rapid decrements respectively；Data 21 ~ 30 are electrode catheter
Implantable intravascular, resistance change from shallow to deep, respectively by 4000 Ω to 2600 Ω, the U-shaped curve of 2600 Ω to 5000 Ω becomes
Change, characterizes electrode catheter at this time and reach target position；Data 31 ~ 40 are that electrode catheter is pierced by blood vessel, leave target from the near to the remote
The resistance change of blood vessel, respectively by the slow incremental variations of 10000 Ω to 27000 Ω；Data 41 ~ 50 are electrode catheter far from mesh
It marks blood vessel and leaves the resistance change of target blood from the near to the remote into other offspring vascular tissues, respectively extremely by 27000 Ω
The slow incremental variations of 33000 Ω；Resistance value curve leading portion data variation is obvious, and Back end data variation is slow.
As shown in Fig. 5, the needle point being implanted into is in tissue location and corresponding electric conductivity value relation schematic diagram, reference electrode
In probe implantable intravascular, each position data of another electrode catheter tissue, data 1 ~ 10 are that electrode catheter is implanted into skin, by
It is shallow to change to deep susceptance value, respectively by the slow incremental variations of 100uS to 400uS；Data 11 ~ 20 are that electrode catheter is implanted into rouge
Fat, susceptance value variation from shallow to deep, respectively by the quick incremental variations of 450uS to 1800uS；Data 21 ~ 30 are electrode catheter plant
Enter blood vessel, susceptance value variation from shallow to deep, respectively by 2000uS to 2500uS, the inverted u-shaped curve of 2500uS to 2000uS becomes
Change, characterizes electrode catheter at this time and reach target position；Data 31 ~ 40 are that electrode catheter is pierced by blood vessel, leave target from the near to the remote
The susceptance value change dramatically of blood vessel is changed by 800uS to 70uS rapid decrement respectively；Data 41 ~ 50 are electrode catheter far from mesh
Blood vessel is marked, into other offspring vascular tissues, the susceptance value variation of target blood is left from the near to the remote, respectively by 50uS to 25uS
Slow variation of successively decreasing；Susceptance value curve leading portion data variation is gentle, and Back end data variation is obvious.In conjunction with resistance Value Data and susceptance
Value Data comprehensive descision more acurrate can judge whether electrode catheter reaches target position.
It can be seen that by above-mentioned, by the real-time detection to electrode catheter, visited so as to accurately control and operate electrode
Needle, the position and depth for being inserted into electrode catheter are all controlled effectively, it is ensured that are accurately inserted into blood vessel.
It should be noted that these are only the preferred embodiment of the present invention, it is not intended to restrict the invention, although ginseng
According to embodiment, invention is explained in detail, for those skilled in the art, still can be to aforementioned reality
Technical solution documented by example is applied to modify or equivalent replacement of some of the technical features, but it is all in this hair
Within bright spirit and principle, any modification, equivalent replacement, improvement and so on should be included in protection scope of the present invention
Within.
Claims (8)
1. a kind of electrode catheter detection device, which is characterized in that described device includes electrode catheter and needle position detection host, the needle
Position detection host includes main control module, detection module, man machine operation interface, communication interface, environmental parameter compensating module and data
Storage center, man machine operation interface, communication interface, environmental parameter compensating module and data storage center arranged in parallel respectively with master
Control module communication connection, detection module respectively with main control module, electrode catheter communication connection.
2. electrode catheter detection device according to claim 1, which is characterized in that the detection module include respectively with electricity
The resistance detection module of pole probe and main control module communication connection, susceptance detection module, capacitive detection module and inductance detection mould
Block.
3. electrode catheter detection device according to claim 2, which is characterized in that the electrode catheter includes reference probe
And it electrode needle, the reference probe and electrode needle and is detected with detection module communication connection, reference probe and electrode needle composition after connecing
The two poles of the earth.
4. electrode catheter detection device according to claim 3, which is characterized in that the reference probe is arranged one group, electricity
Needle setting in pole is at least one set of.
5. electrode catheter detection device according to claim 4, which is characterized in that the communication interface connects for fixed network
Mouth, radio network interface or interface of internet of things.
6. electrode catheter detection device according to claim 5, which is characterized in that the main control chip of the main control module is
Single-chip microcontroller, digital information processing system chip DSP or embedded system chip.
7. a kind of application method of electrode catheter detection device according to claim 6, comprising the following steps:
It is first implanted into reference probe in the arteries or vein blood vessel of affected areas tissue regions, is replanted into electrode needle, benchmark is visited
The two poles of the earth of needle and electrode needle composition detection；
The data information that detection module will test by reference probe and electrode needle feeds back the main control module root into main control module
According to the data in data storage center, the insertion situation of current reference probe and electrode needle is judged, and will be inserted into situation in people
It is displayed for checking in machine operation interface.
8. the application method of electrode catheter detection device according to claim 1, which is characterized in that the detection module will
After the data information detected feeds back to main control module, main control module carries out compensation data, revised number according to environmental parameter
It is compared according to the data with data storage center, so that judgement obtains the insertion situation of reference probe and electrode needle.
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| CN201811600508.XA CN109568124A (en) | 2018-12-26 | 2018-12-26 | A kind of electrode catheter detection device and its application method |
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| CN201811600508.XA CN109568124A (en) | 2018-12-26 | 2018-12-26 | A kind of electrode catheter detection device and its application method |
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Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86105980A (en) * | 1986-09-09 | 1988-03-23 | 顾涵森 | Bioelectric signal measuring apparatus |
| TW197943B (en) * | 1992-07-22 | 1993-01-11 | Jih Hua Co Ltd | Precision acupuncture tester |
| CN1391104A (en) * | 2001-06-12 | 2003-01-15 | 生命扫描有限公司 | Device and method for sampling and testing components of biologic fluid via skin |
| KR100579936B1 (en) * | 2004-11-30 | 2006-05-15 | 주식회사 에스피메디텍 | An apparatus measuring parameter of cerebrovascular and method thereof |
| CN101011247A (en) * | 2006-02-04 | 2007-08-08 | 霍夫曼-拉罗奇有限公司 | Puncturing device with impedance measuring facility |
| CN101361696A (en) * | 2008-09-25 | 2009-02-11 | 东南大学 | Electronic informatics measuring method and device for human channels and collaterals |
| CN103069001A (en) * | 2010-06-23 | 2013-04-24 | 美敦力迷你迈德公司 | Sensor systems having multiple probes and electrode arrays |
| CN107206230A (en) * | 2015-02-03 | 2017-09-26 | 罗琮柱 | The therapeutic system of blood vessel in skin |
| CN107233664A (en) * | 2017-07-18 | 2017-10-10 | 南京骓迈医疗科技有限公司 | A kind of electroacupuncture treatment system based on acupoint impedance |
| CN109010011A (en) * | 2018-08-17 | 2018-12-18 | 广州中医药大学(广州中医药研究院) | A kind of ear acupuncture point detector |
-
2018
- 2018-12-26 CN CN201811600508.XA patent/CN109568124A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86105980A (en) * | 1986-09-09 | 1988-03-23 | 顾涵森 | Bioelectric signal measuring apparatus |
| TW197943B (en) * | 1992-07-22 | 1993-01-11 | Jih Hua Co Ltd | Precision acupuncture tester |
| CN1391104A (en) * | 2001-06-12 | 2003-01-15 | 生命扫描有限公司 | Device and method for sampling and testing components of biologic fluid via skin |
| KR100579936B1 (en) * | 2004-11-30 | 2006-05-15 | 주식회사 에스피메디텍 | An apparatus measuring parameter of cerebrovascular and method thereof |
| CN101011247A (en) * | 2006-02-04 | 2007-08-08 | 霍夫曼-拉罗奇有限公司 | Puncturing device with impedance measuring facility |
| CN101361696A (en) * | 2008-09-25 | 2009-02-11 | 东南大学 | Electronic informatics measuring method and device for human channels and collaterals |
| CN103069001A (en) * | 2010-06-23 | 2013-04-24 | 美敦力迷你迈德公司 | Sensor systems having multiple probes and electrode arrays |
| CN107206230A (en) * | 2015-02-03 | 2017-09-26 | 罗琮柱 | The therapeutic system of blood vessel in skin |
| CN107233664A (en) * | 2017-07-18 | 2017-10-10 | 南京骓迈医疗科技有限公司 | A kind of electroacupuncture treatment system based on acupoint impedance |
| CN109010011A (en) * | 2018-08-17 | 2018-12-18 | 广州中医药大学(广州中医药研究院) | A kind of ear acupuncture point detector |
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Application publication date: 20190405 |
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