CN109550030A - A kind of dipping Chinese medicine for preventing and treating icterus neonatorum - Google Patents
A kind of dipping Chinese medicine for preventing and treating icterus neonatorum Download PDFInfo
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Abstract
The present invention relates to the dipping Chinese medicines of prevention and treatment icterus neonatorum, it can effectively solve efficiently, the medication problem for the treatment of icterus neonatorum at low cost, its solve technical solution be, by the material medicine of following poidometer: oriental wormwood 13-17g, cape jasmine 9-11g, vinegar Radix Curcumae 9-11g, Bupleurum Chinese 4-6g, stir-baked FRUCTUS AURANTII in bran 4-6g, Rhizoma Atractylodis Macrocephalae 9-11g, stir-baked FRUCTUS CRATAEGI 9-11g, Poria cocos 9-11g, radix pseudostellariae 9-11g, Radix Salviae Miltiorrhizae 9-11g, caulis lonicerae 13-17g, honeysuckle 9-11g and Radix Glycyrrhizae 4-6g are made, first material medicine is mixed, it crushes, cross 30-60 mesh, at medicinal powder, it is reloaded into non-woven bag, .Prescription of the present invention is scientific and reasonable, and abundant raw material, preparation method is simple, preparation easy to produce, easy to use, and effect is good, can be effectively used for prevention and treatment icterus neonatorum, is the innovation treated on icterus neonatorum drug, there is good economic and social benefit.
Description
Technical field
The present invention relates to medicine, especially a kind of dipping Chinese medicine for preventing and treating icterus neonatorum.
Background technique
Jaundice in neonatal period belongs to a kind of disease of newborn Yi Fa, and disease incidence is high, accounts for 30-50%, neonatal period is to point out
28d after life to life causes blood mesobilirubin horizontal abnormality to increase more than 5~7mL/dL, to lead due to bilirubin metabolism exception
The clinical picture of skin, mucous membrane, sclera and whole body its hetero-organization xanthochromia is caused, the normal growth and development of infant is not only influenced, but also
The physical and mental health for seriously affecting parent brings heavy burden to society.Jaundice Crack cause includes that bilirubin generates excessive, liver
Cellular uptake and combination bilirubin inferior capabilities, bilirubin excretion exception, intestines liver circulation increase, if Neonatal jaundice therapy is not
When unconjugated bilirubin can be made to enter brain through blood-brain barrier, lead to bilirubin encephalopathy, serious patient can lead to death.Though existing
There are a variety of drugs for the treatment of jaundice in neonatal period, as oriental wormwood removing jaundice soup treats icterus neonatorum [ J ] China combination of Chinese tradiational and Western medicine paediatrics
Learn, 2018,10(2): 182-184, it is (clinical see Chinese material bathe treatment icterus neonatorum that there are also Chinese material bathe treatment icterus neonatorums
Observation and beta-glucuronidase level probe into [ J ] .2018,30(7): 1307-1310 [ 2 ]), " preventive treatment of disease " thought in Chinese medicine
Under guidance, newborn extremely raised for serum bilirubin selects the preventative carry out washout of effective formula and drug, it will significantly drop
The generation of low pathological jaundice or the symptom and harm for mitigating pathological jaundice reduce medical treatment to improve newborn's survival rate
Expense.But the problem as present on drug, its curative effect of drug therapy jaundice in neonatal period and use at present is simultaneously unsatisfactory, because
The improvement and innovation of this treatment jaundice in neonatal period drug are imperative.
Summary of the invention
For above situation, for the defect for overcoming the prior art, the purpose of the present invention is just to provide a kind of prevention and treatment newborn
The dipping Chinese medicine of jaundice can effectively solve the problems, such as the medication for the treatment of icterus neonatorum efficient, at low cost.
The technical solution that the present invention solves is that a kind of dipping Chinese medicine for preventing and treating icterus neonatorum, is by following poidometer
Material medicine: oriental wormwood 13-17g, cape jasmine 9-11g, vinegar Radix Curcumae 9-11g, Bupleurum Chinese 4-6g, stir-baked FRUCTUS AURANTII in bran 4-6g, Rhizoma Atractylodis Macrocephalae 9-11g,
Stir-baked FRUCTUS CRATAEGI 9-11g, Poria cocos 9-11g, radix pseudostellariae 9-11g, Radix Salviae Miltiorrhizae 9-11g, caulis lonicerae 13-17g, honeysuckle 9-11g and Radix Glycyrrhizae 4-
6g is made, and first mixes material medicine, crushes, and crosses 30-60 mesh and is reloaded into non-woven bag at medicinal powder,.
Prescription of the present invention is scientific and reasonable, and abundant raw material, preparation method is simple, preparation easy to produce, easy to use, and effect is good,
It can be effectively used for prevention and treatment icterus neonatorum, be the innovation treated on icterus neonatorum drug, there is good economic and social benefit.
Specific embodiment
It elaborates with reference to embodiments to a specific embodiment of the invention.
The present invention can be realized in specific implementation by following embodiment.
Embodiment 1
In specific implementation, a kind of dipping Chinese medicine for preventing and treating icterus neonatorum, is by the material medicine of following poidometer to the present invention:
Oriental wormwood 15g, cape jasmine 10g, vinegar Radix Curcumae 10g, Bupleurum Chinese 5g, stir-baked FRUCTUS AURANTII in bran 5g, Rhizoma Atractylodis Macrocephalae 10g, stir-baked FRUCTUS CRATAEGI 10g, Poria cocos 10g, crown prince
Ginseng 10g, Radix Salviae Miltiorrhizae 10g, caulis lonicerae 15g, honeysuckle 10g and Radix Glycyrrhizae 5g are made, and first mix material medicine, crush, and cross 30-60 mesh
Sieve, at medicinal powder, is reloaded into non-woven bag,.
Embodiment 2
In specific implementation, a kind of dipping Chinese medicine for preventing and treating icterus neonatorum, is by the material medicine of following poidometer to the present invention:
Oriental wormwood 14g, cape jasmine 10.5g, vinegar Radix Curcumae 9.5g, Bupleurum Chinese 5.5g, stir-baked FRUCTUS AURANTII in bran 4.5g, Rhizoma Atractylodis Macrocephalae 10.5g, stir-baked FRUCTUS CRATAEGI 9.5g, Fu
Siberian cocklebur 10.5g, radix pseudostellariae 9.5g, Radix Salviae Miltiorrhizae 10.5g, caulis lonicerae 14g, honeysuckle 10.5g and Radix Glycyrrhizae 4.5g are made, first by material medicine
Mixing crushes, and crosses 30-60 mesh and is reloaded into non-woven bag at medicinal powder,.
Embodiment 3
In specific implementation, a kind of dipping Chinese medicine for preventing and treating icterus neonatorum, is by the material medicine of following poidometer to the present invention:
Oriental wormwood 16g, cape jasmine 9.5g, vinegar Radix Curcumae 10.5g, Bupleurum Chinese 4.5g, stir-baked FRUCTUS AURANTII in bran 5.5g, Rhizoma Atractylodis Macrocephalae 9.5g, stir-baked FRUCTUS CRATAEGI 10.5g, Fu
Siberian cocklebur 9.5g, radix pseudostellariae 10.5g, Radix Salviae Miltiorrhizae 9.5g, caulis lonicerae 16g, honeysuckle 9.5g and Radix Glycyrrhizae 5.5g are made, and first mix material medicine
It closes, crushes, cross 30-60 mesh and be reloaded into non-woven bag at medicinal powder,.
In said medicine, in which:
Oriental wormwood: it is mentioned on the dry ground harvested for compositae plant shore nest or oriental wormwood nest spring, made of part (capillary wormwood) is extracted
Take object gas fragrant, it is bitter, pungent, it is slightly cold.Returns spleen, stomach, liver, gallbladder channel.[function and cure mainly] eliminating dampness and heat, normalizing gallbladder to cure jaundice.For jaundice
Oliguria, damp-warm syndrome summer-heat and damp, itchy sore;
Cape jasmine: it is bitter in taste, it trembles with fear.Return heart, lung, tri-jiao channel.Purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body；Externally used detumescence analgesic.With
In Vexed, jaundice with damp-heat pathogen, the puckery pain of stranguria " blood-head tells nosebleed, red eye, swell pain, fire toxin all sores；Bruise pain is controlled outside.
Vinegar Radix Curcumae: it is pungent, bitter, it trembles with fear.Return liver, the heart, lung channel.[function and cure mainly] promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood,
Normalizing gallbladder to cure jaundice.For pricking pain in the chest, chest impediment and cardialgia, amenorrhea and algomenorrhea, swollen breasts, pyreticosis coma, epilepsy goes mad, blood-head tells nosebleed,
Jaundice and reddish urine.
Bupleurum Chinese: it is pungent, bitter, it is slightly cold.Return liver, gallbladder, lung channel.[function with cure mainly] evacuation is brought down a fever, and soothing liver-qi stagnation rises and lifts sun
Gas.For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, uterine prolapse, rectal prolapse.
Stir-baked FRUCTUS AURANTII in bran: it is bitter, pungent, sour, it is slightly cold.Returns spleen, stomach meridian.[function and cure mainly] regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row.For chest
The stagnation of the circulation of vital energy, turgor pain are coerced, accumulation of food in the stomach and intes tine due to indigestion stops in phlegm retention, visceral organ ptosis.
Rhizoma Atractylodis Macrocephalae: this product is thousand dry rhizomes of compositae plant Rhizoma Atractylodis Macrocephalae, and property is hidden and channel tropism J hardship, sweet, warm.Returns spleen, stomach meridian.[function
With cure mainly] Jian spleen QI invigorating, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration,
Threatened abortion.
Stir-baked FRUCTUS CRATAEGI: sour, sweet, tepor.Returns spleen, stomach, Liver Channel.[function and cure mainly] scattered stasis, changes turbid lipid-loweringing.For meat
It is stagnant, gastral cavilty turgor, diarrhea dysentery abdominal pain, blood stasis closed, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipidemia.
Charred FRUCTUS CRATAEGI promoting digestion effect enhancing.For meat stagnation, dysentery is not well.
Poria cocos: it is sweet, light, it puts down.Return heart, lung, spleen, kidney channel.[function and cure mainly] clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema
Oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Radix pseudostellariae: it is sweet, bitter, it puts down.Returns spleen, lung channel.[function with cure mainly] replenishes qi to invigorate the spleen, promoting production of body fluid and nourishing the lung.It is tired for spleen deficiency body,
Loss of appetite, eak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration and thirst, dryness of the lung dry cough.
Radix Salviae Miltiorrhizae: it is bitter, it is slightly cold.Converge to heart and liver channels.[function and cure mainly] promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood disappears
Carbuncle.For chest impediment and cardialgia, stomach duct and abdomen hypochondriac pain , lumps in the chest and abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea menostasis, sore is swollen
Bitterly.
Caulis lonicerae: it is sweet, it trembles with fear.It attaches to the lung and stomach meridians.[function with cure mainly] is clearing heat and detoxicating, dredges phoenix dredging collateral.For warm disease heating, heat
Malicious bloody flux, carbuncle swells sore, beriberoid pyretic arthralgia, the red arsine heat pain in joint.
Honeysuckle: it is sweet, it trembles with fear.Return lung, the heart, stomach meridian.[function with cure mainly] clearing heat and detoxicating, dispelling wind and heat from the body.For carbuncle swells furunculosis,
Sore throat, erysipelas, toxic-heat and blood stasis, wind-heat cold, warm disease and fever.
Radix Glycyrrhizae: it is sweet, it puts down.Return heart, lung, spleen, stomach meridian.[function and cure mainly] , Cheongju thermal detoxification of invigorating the spleen and benefiting qi, expelling phlegm and arresting coughing delay
Anxious analgesic, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle
Swollen sore alleviates drug toxicity, strong.
Said medicine efficient combination supports there is clearing heat and detoxicating, dispelling wind and eliminating dampness, qi-regulating easypro liver, strengthening the spleen and stomach, benefit mutually
Gallbladder dispel Huang the effect of, effective for prevent and treat icterus neonatorum (disease), and through experiment achieve extraordinary advantageous effects, have
It is as follows to close experimental data:
To the newborn of 28d after raw, serum bilirubin increases extremely for all births, the alternatively standard of case, and uses
Chinese medicine of the present invention carries out dipping.Therapeutic scheme is that Chinese medicine 125g of the present invention is packed into non-woven bag, prevents adding water 60- into bathtub
70 liters are soaked into water-bath medical fluid, 36-38 DEG C of water temperature, 26-28 DEG C of room temperature, have a new student in each bathtub, newborn is allowed to exist
Swimming in bathtub, carries out dipping, once a day, 20-30 minutes each, 7 days courses for the treatment of.8 hours after newborn's birth, to breast milk
It can start within 60 minutes, one-to-one operation is carried out by the nurse Jing Guo professional training.Neonatal clothing is sloughed with soft movement
Clothes, and waterproof navel patch is sticked in umbilical region, safe swim ring is put on according to specification, there are commonly international pharmaceutical grade KPU materials
The swim ring with dual fail-safe and music of production, it is lightly into the water by newborn, main to neonatal four limbs in pond
The positions such as joint, including shoulder, elbow, wrist, knee and ankle-joint carry out regular passive relaxing exercise, and 8 to be born from newborn are small
When, serum bilirubin is percutaneously surveyed in daily 8:00-9:00, measurement site is forehead center, shirtfront and big leg outer side, takes it
Average value.
According to the above technical scheme, through checking certain hospital's full-term normal delivery, breast-feeding, direct rooming-in, no asphyxia history, mother
Normal newborn 100 is used as experimental subjects, is randomly divided into two groups, every group each 50 yuan.Control group 50, wherein boy baby 28
Example, girl baby 22；Pregnant 37-42 weeks, average pregnant week (39.54 ± 0.27) week；Weight 2.5- 4.2kg, average weight (3.33 ±
0.42) kg.Observation group's (Chinese medicine group of the present invention) 50, wherein boy baby 29, girl baby 21；Pregnant 37-42 weeks, average pregnant week
(39.69 ± 0.35) all；Weight 2.5-4.25kg, average weight (3.34 ± 0.47) kg.Two groups of neonatal genders, pregnant weeks
Compare with general information such as weight, no significant difference (P > 0.05) is comparable.
Observation index
Two groups of neonatal meconiums turn yellow time, percutaneous ballon mitral valvuloplasty value are counted, the hair of hyperbilirubinemia is recorded
Raw situation.
Observing two groups of neonatal skin integrities, umbilical region clean level and other adverse reactions, a situation arises, and
It is recorded.
8 hours, bilirubin is percutaneously measured in daily 8:00-9:00, measurement site is forehead after newborn's birth
Center, shirtfront and big leg outer side, take its average value.
Statistical procedures
Data processing is carried out using 19.0 software of SPSS, measurement data is indicated with x ± s, is examined using t, and enumeration data is with hundred
Divide than indicating, using χ2It examines, P < 0.05 is that difference has statistical significance.
Two groups of icterus neonatorum situations compare
The meconium of observation group turns yellow, the removing jaundice time is considerably shorter than control group, and the incidence of hyperbilirubinemia is 6.07 %,
Substantially less than 17.35 % of control group, difference have statistical significance (P < 0.05), dipping Chinese medicine effective percentage 100% of the present invention.
Conclusion
Hyperbilirubinemia of newborn is non-neonate common disease, refer to neonatal period due to bilirubin metabolism exception, from
And lead to the clinical picture of its hetero-organization xanthochromia of skin, mucous membrane, sclera and whole body, the normal growth and development of infant is not only influenced,
And the physical and mental health of parent is seriously affected, heavy burden is brought to society.Jaundice Crack cause includes that bilirubin generated
More, liver cell intake and combination bilirubin inferior capabilities, bilirubin excretion exception, intestines liver circulation increase.If icterus neonatorum is controlled
It is improper to treat, and unconjugated bilirubin can be made to enter brain through blood-brain barrier, lead to bilirubin encephalopathy, serious patient can lead to death.
Chinese medicine " preventive treatment of disease " thought guidance under, newborn extremely raised for serum bilirubin, select effective formula and drug it is preventative
Carry out washout, it will the generation of pathological jaundice is greatly lowered or mitigates the symptom and harm of pathological jaundice, to improve
Newborn's survival rate reduces medical expense.
Chinese prescription of the present invention is scientific and reasonable, preparation easy to produce, easy to use, and effect is good, and expense is low, props up mutually between drug
Hold, have clearing heat and detoxicating, dispelling wind and eliminating dampness, qi-regulating relax liver, strengthening the spleen and stomach, cholagogue dispel Huang the effect of, effective for preventing and treating newborn
Jaundice (disease), in only experiment, for effective percentage up to 100%, expense can reduce by 50%, and have no adverse reaction, and show drug safety, treat
It imitates reliable and stable, is the innovation prevented and treated on icterus neonatorum disease, economic and social benefit is huge.
Claims (4)
1. a kind of dipping Chinese medicine for preventing and treating icterus neonatorum, which is characterized in that by the material medicine of following poidometer: oriental wormwood 13-
17g, cape jasmine 9-11g, vinegar Radix Curcumae 9-11g, Bupleurum Chinese 4-6g, stir-baked FRUCTUS AURANTII in bran 4-6g, Rhizoma Atractylodis Macrocephalae 9-11g, stir-baked FRUCTUS CRATAEGI 9-11g, Poria cocos
9-11g, radix pseudostellariae 9-11g, Radix Salviae Miltiorrhizae 9-11g, caulis lonicerae 13-17g, honeysuckle 9-11g and Radix Glycyrrhizae 4-6g are made, first by bulk pharmaceutical chemicals
Object mixing, crushes, and crosses 30-60 mesh and is reloaded into non-woven bag at medicinal powder,.
2. the dipping Chinese medicine of prevention and treatment icterus neonatorum according to claim 1, which is characterized in that by the original of following poidometer
Expect drug: oriental wormwood 15g, cape jasmine 10g, vinegar Radix Curcumae 10g, Bupleurum Chinese 5g, stir-baked FRUCTUS AURANTII in bran 5g, Rhizoma Atractylodis Macrocephalae 10g, stir-baked FRUCTUS CRATAEGI 10g, Poria cocos
10g, radix pseudostellariae 10g, Radix Salviae Miltiorrhizae 10g, caulis lonicerae 15g, honeysuckle 10g and Radix Glycyrrhizae 5g are made, and first mix material medicine, crush,
30-60 mesh is crossed, at medicinal powder, is reloaded into non-woven bag,.
3. the dipping Chinese medicine of prevention and treatment icterus neonatorum according to claim 1, which is characterized in that by the original of following poidometer
Expect drug: oriental wormwood 14g, cape jasmine 10.5g, vinegar Radix Curcumae 9.5g, Bupleurum Chinese 5.5g, stir-baked FRUCTUS AURANTII in bran 4.5g, Rhizoma Atractylodis Macrocephalae 10.5g, stir-baked FRUCTUS CRATAEGI
9.5g, Poria cocos 10.5g, radix pseudostellariae 9.5g, Radix Salviae Miltiorrhizae 10.5g, caulis lonicerae 14g, honeysuckle 10.5g and Radix Glycyrrhizae 4.5g are made, and first will
Material medicine mixing, crushes, and crosses 30-60 mesh and is reloaded into non-woven bag at medicinal powder,.
4. the dipping Chinese medicine of prevention and treatment icterus neonatorum according to claim 1, which is characterized in that by the original of following poidometer
Expect drug: oriental wormwood 16g, cape jasmine 9.5g, vinegar Radix Curcumae 10.5g, Bupleurum Chinese 4.5g, stir-baked FRUCTUS AURANTII in bran 5.5g, Rhizoma Atractylodis Macrocephalae 9.5g, stir-baked FRUCTUS CRATAEGI
10.5g, Poria cocos 9.5g, radix pseudostellariae 10.5g, Radix Salviae Miltiorrhizae 9.5g, caulis lonicerae 16g, honeysuckle 9.5g and Radix Glycyrrhizae 5.5g are made, first will be former
Expect drug mixing, crush, crosses 30-60 mesh and be reloaded into non-woven bag at medicinal powder,.
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Citations (4)
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| CN1742980A (en) * | 2005-10-01 | 2006-03-08 | 南宁市第一人民医院 | Chinese medicinal lotion for new-borne baby's removing jaundice |
| CN103638161A (en) * | 2013-12-06 | 2014-03-19 | 杜士明 | Preparation method and application of Jinyin heat clearing oral liquid |
| CN106389947A (en) * | 2016-10-21 | 2017-02-15 | 代立新 | Traditional Chinese medicine for curing neonatal jaundice and preparation method thereof |
| WO2018101515A1 (en) * | 2016-12-01 | 2018-06-07 | 정희권 | Method for manufacturing mushroom fritters |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1742980A (en) * | 2005-10-01 | 2006-03-08 | 南宁市第一人民医院 | Chinese medicinal lotion for new-borne baby's removing jaundice |
| CN103638161A (en) * | 2013-12-06 | 2014-03-19 | 杜士明 | Preparation method and application of Jinyin heat clearing oral liquid |
| CN106389947A (en) * | 2016-10-21 | 2017-02-15 | 代立新 | Traditional Chinese medicine for curing neonatal jaundice and preparation method thereof |
| WO2018101515A1 (en) * | 2016-12-01 | 2018-06-07 | 정희권 | Method for manufacturing mushroom fritters |
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