CN109528356B

CN109528356B - Composite insert

Info

Publication number: CN109528356B
Application number: CN201910054113.2A
Authority: CN
Inventors: 王彩梅; 周一新; 周梦
Original assignee: Beijing AK Medical Co Ltd
Current assignee: Beijing AK Medical Co Ltd
Priority date: 2019-01-21
Filing date: 2019-01-21
Publication date: 2021-01-26
Anticipated expiration: 2039-01-21
Also published as: CN109528356A

Abstract

The invention provides a composite insert which can be implanted into a target bone, the composite insert comprises a fixing part and a friction part, the fixing part can be fixedly connected with the target bone, the friction part is arranged on the fixing part, the wear resistance of the friction part is better than that of the fixing part, and the fixing part comprises a porous structure. The technical scheme of the invention effectively solves the problem that an effective means for intervening femoral head lesion is lacking clinically in the prior art.

Description

Composite insert

Technical Field

The invention relates to the field of orthopedic surgery implants, in particular to a composite insert.

Background

Articular cartilage damage is a common disease in orthopedics. In the field of orthopedic surgery, arthritis caused by traumatic and degenerative cartilage tissue injury due to diseases, wounds and the like is a problem in the medical field all over the world, and the cartilage tissue has no blood supply, and nutrition comes from moistening of peripheral joint synovial fluid, so that regeneration is difficult after injury. Traditional methods for treating cartilage damage include joint grinding, drilling, microfracture, and arthroscopic lavage, which fail to restore damaged cartilage and subchondral bone to their original normal tissue structures. The autologous tissue transplantation has better curative effect but limited material supply; foreign materials are relatively abundant in origin, but may cause immune rejection and risk of disease transmission. Currently, the development of tissue substitutes for damaged tissue using tissue engineering is currently in the laboratory research phase, and there is no more effective treatment available.

Thighbones are the most important bones of human bodies, the thighbones are more important, and the supporting function of the thighbones is relied on for the vertical walking, the movement and the labor of people. The femoral head is also the most vulnerable site. After the femoral head is diseased, a severe patient can have bone fracture, a trabecula disappears or most of the trabecula disappears, large-area saccular light transmission at multiple positions in the femoral head changes, multiple positions of sclerotic high-density bone changes, the femoral head seriously collapses and deforms, and is flat and large, so hip joint pain, joint function limitation, walking lameness and other symptoms are often caused. If not effectively treated early, the femoral head will eventually be cut off and hip replacement surgery performed clinically in the late stages of the patient. Therefore, early intervention plays an important role in retaining the femoral head and preventing rapid disease deterioration, but currently, clinically effective intervention means are lacking.

Disclosure of Invention

The invention aims to provide a composite insert to solve the problem that an effective means for intervening femoral head lesion is lacking clinically in the prior art.

In order to achieve the above object, according to one aspect of the present invention, there is provided a composite insert implantable in a target bone, the composite insert comprising a fixing portion capable of being fixedly connected with the target bone and a friction portion provided on the fixing portion, the friction portion having a wear resistance superior to that of the fixing portion, the fixing portion comprising a porous structure.

Further, the fixation part further comprises a support structure, the porous structure comprising a first porous structure and a second porous structure, the first porous structure being arranged on a side of the support structure facing the target bone, and the second porous structure being arranged on a side of the support structure facing the friction part.

Further, the support structure comprises a first support part and a positioning convex part, the first porous structure is arranged on one side of the first support part facing the target bone, the second porous structure is arranged on one side of the first support part facing the friction part, and the positioning convex part can extend into the positioning hole of the friction part.

Furthermore, the positioning convex part is provided with a necking part, and the shape of the positioning hole is matched with that of the positioning convex part.

Further, the first support part is in a cone shape, and the positioning convex part extends from the side with the smaller diameter of the cone-shaped first support part to the side with the larger diameter.

Furthermore, the supporting structure also comprises a second supporting piece, the second supporting piece is arranged at the opening of the first supporting piece and is connected with the end part of the first supporting piece, part of the second porous structure is arranged along one side surface of the second supporting piece facing the target bone and protrudes inwards to form a clamping part, and the friction part is provided with a concave part matched with the clamping part.

Further, the fixing portion further includes a third porous structure disposed on a side of the second support facing the friction portion.

Further, the support structure further comprises a reinforcing rib, and the reinforcing rib is arranged on the first support piece along a direction perpendicular to the axis of the support structure.

Further, the friction part is also provided with a wrapping edge, and the first porous structure is provided with an avoiding part matched with the wrapping edge.

Further, the support structure, the first porous structure and the second porous structure are made by 3D printing techniques.

Further, the friction portion is injection molded.

Further, the target bone is the femoral head.

By applying the technical scheme of the invention, the fixing part and the friction part are respectively arranged according to different structural requirements on two sides of the insert, the wear resistance of the friction part is similar to that of the native cartilage of a patient, and the joint function of a diseased region can be filled and reconstructed; the fixing part is used for fixing the friction part, the porous structure can form a structure similar to a bone trabecula, and bone of a target bone can grow into pores of the porous structure along with the growth of the bone of a patient after operation, so that the fixation is facilitated. The fixing part and the friction part are fixedly connected together to form the composite insert. By implanting the composite insert to replace a diseased region in a target bone, the stress environment of the diseased region of the target bone is effectively improved, and rapid stress collapse caused by the diseased region is resisted.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the invention and, together with the description, serve to explain the invention and not to limit the invention. In the drawings:

FIG. 1 shows a schematic cross-sectional structural view of a first embodiment of a composite insert according to the present invention;

FIG. 2 shows a schematic structural view of the fixed portion of the composite insert of FIG. 1;

FIG. 3 shows a schematic view of the friction portion of the composite insert of FIG. 1;

FIG. 4 shows a schematic cross-sectional structural view of a second embodiment of a composite insert according to the present invention;

FIG. 5 shows a schematic view of the fastening portion of the composite insert of FIG. 4; and

FIG. 6 shows a schematic view of the friction portion of the composite insert of FIG. 4.

Wherein the figures include the following reference numerals:

10. a support structure; 11. a first support member; 12. a second support member; 13. a positioning projection; 14. shrinking the neck part; 15. reinforcing ribs; 20. a porous structure; 21. a first porous structure; 22. a second porous structure; 23. a third porous structure; 24. a clamping part; 25. an avoidance part; 30. a friction portion; 31. a friction surface; 32. positioning holes; 33. a recessed portion; 34. and (6) edge covering.

Detailed Description

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.

The first embodiment is as follows:

the composite insert of the present application can be implanted into a femoral head with a femoral head as a target bone, as shown in fig. 1 to 3, the composite insert of the first embodiment includes a fixing portion and a friction portion 30, the fixing portion can be fixedly connected with the femoral head, the friction portion 30 is disposed on the fixing portion, the wear resistance of the friction portion 30 is better than that of the fixing portion, and the fixing portion includes a porous structure 20.

By applying the technical scheme of the embodiment, the fixing part and the friction part 30 are respectively arranged according to different structural requirements on two sides of the insert, the wear resistance of the friction part 30 is similar to that of the native femoral cartilage of a patient, and the joint function of a diseased region can be filled and reconstructed; the fixing part is used for fixing the friction part 30, the porous structure 20 can form a structure similar to a bone trabecula, and bone of femoral head can grow into pores of the porous structure 20 along with the growth of bones of a patient after operation, so that the fixation is facilitated. The fixed portion and the friction portion 30 are fixedly connected together to form a composite insert, so that the composite insert has structural stability of connection with the femur and physical properties close to those of the contact surface of the acetabulum. By implanting the composite insert block to replace a diseased region in the femoral head, the stress environment of the diseased region of the femoral head is effectively improved, and rapid stress collapse caused by the diseased region is resisted.

The friction portion 30 may be made of polyurethane and formed by thermoplastic injection molding according to the structural characteristics of the cartilage on the femoral head. When the composite insert is implanted into the femoral head, the friction surface 31 of the friction part 30 is flush with the outer surface of the femoral head so as to fill up the defect of the primary bone in the pathological change area and restore the physiological function of the femoral head.

As shown in fig. 1 and 2, the anchoring portion of the present embodiment further comprises a support structure 10, the support structure 10 preferably being a solid structure to provide skeletal support for the porous structure 20. The porous structure 20 comprises a first porous structure 21 and a second porous structure 22, the first porous structure 21 being arranged on the side of the support structure 10 facing the femur for improving the integration of the composite insert with the femoral head; the second porous structure 22 is arranged on the side of the support structure 10 facing the friction portion 30, and during the thermoplastic injection molding of the polyurethane material, the still liquid polyurethane material can penetrate into the pores of the second porous structure 22, and can be firmly connected with the second porous structure 22 when the polyurethane material is solidified into a solid. The solid support structure 10 is able to naturally form a barrier layer preventing the polyurethane material from seeping out.

Preferably, the support structure 10, the first porous structure 21 and the second porous structure 22 of the present embodiment are integrally formed by a 3D printing technique. The structure fully utilizes the excellent osseointegration function and the physiological bone self-healing function of the 3D printing bone trabecula porous structure to rebuild the expected effect of excellent bone and joint functions. In order for the porous structure 20 to function close to the femoral head bone, the first porous structure 21 and the second porous structure 22 should have a pore size of less than 1 mm.

As shown in fig. 2 and 3, the support structure 10 of the present embodiment includes a first support 11 and a positioning protrusion 13, a first porous structure 21 is provided on a side of the first support 11 facing the femoral head, a second porous structure 22 is provided on a side of the first support 11 facing the friction portion 30, and the first support 11 plays a role of supporting and isolating between the first porous structure 21 and the second porous structure 22. The positioning convex part 13 can extend into the positioning hole 32 of the friction part 30 to fix the relative position between the friction part 30 and the fixing part, thereby improving the structural stability of the composite insert and reducing the material consumption of polyurethane. Specifically, the positioning protrusion 13 of the present embodiment has a constricted portion 14, and the positioning hole 32 is shaped to fit the positioning protrusion 13. The necked-down portion 14 is in a first abutting relationship with the inner wall of the positioning hole 32 of the friction portion to prevent the friction portion 30 from separating from the fixing portion.

The first supporting part 11 is conical, and the positioning convex part 13 extends from the side with the smaller diameter of the conical first supporting part 11 to the side with the larger diameter, so that the side of the composite insert, which faces the femoral head, is conical, and the composite insert is convenient to implant.

As shown in fig. 2 and 3, the supporting structure 10 of the present embodiment further includes a second supporting member 12, the second supporting member 12 is disposed at the opening of the first supporting member 11 and is connected to the supporting structure 10 with the end of the first supporting member 11, and the second supporting member 12 provides a supporting plane for the edge of the friction part 30. A portion of the second porous structure 22 is disposed along a side surface of the second support 12 facing the femoral head and projects inwardly to form a snap-fit portion 24. The friction portion 30 has a recess 33 adapted to the snap portion 24. The snap-in portion 24 and the recessed portion 33 form a second abutting relationship, further avoiding the friction portion 30 from separating from the fixing portion. Meanwhile, because the first support piece 11 is tapered to form a trend of narrow lower part and wide upper part, the necking part 14 and the clamping part 24 occupy a part of space in the tapered space formed by the first support piece 11 in an enclosing manner, so that the thickness of the part of the friction part 30 matched with the fixing part is relatively uniform, the injection molding is facilitated, and the injection molding quality is ensured.

Example two:

the composite insert of the second embodiment changes the specific structure of the support structure 10, the porous structure 20 and the friction part 30 on the basis of the first embodiment, as shown in fig. 4 to 6, the fixing part of the second embodiment further includes a third porous structure 23, the third porous structure 23 is disposed on the side of the second support 12 facing the friction part 30, and during the injection molding process, the polyurethane material can also penetrate into the pores of the third porous structure 23, so as to further improve the connection strength between the friction part 30 and the fixing part.

Meanwhile, the friction part 30 of the present embodiment further has a covered edge 34, and the first porous structure 21 has an escape part 25 adapted to the covered edge 34. The matching of the edge cover 34 and the avoiding part 25 reduces the possibility that the edge of the friction part 30 is separated from the edge of the fixed part and is lifted, and the function of the composite insert is influenced.

As shown in fig. 5, the support structure 10 of the present embodiment further includes a reinforcing rib 15, the reinforcing rib 15 is disposed on the first support 11 in a direction perpendicular to the axis of the support structure 10, and the first porous structure 21 is divided into three parts by the reinforcing rib 15 and the second support 12.

From the above description, it can be seen that the above-described embodiments of the present invention achieve the following technical effects:

the fixing part and the friction part are respectively arranged according to different structural requirements on two sides of the insert, the wear resistance of the friction part is similar to that of the native femoral cartilage of a patient, and the joint function of a diseased region can be filled and reconstructed; the fixing part is used for fixing the friction part, the porous structure can form a structure similar to a bone trabecula, and along with the growth of the bone of a patient after operation, bone of femoral head can grow into the pores of the porous structure, so that the fixation is facilitated. The fixing part and the friction part are fixedly connected together to form the composite insert. By implanting the composite insert block to replace a diseased region in the femoral head, the stress environment of the diseased region of the femoral head is effectively improved, and rapid stress collapse caused by the diseased region is resisted.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A composite insert implantable in a target bone, characterized in that it comprises a fixation part which can be fixedly connected with the target bone, and a friction part (30) arranged on the fixation part, the friction part (30) having a better wear resistance than the fixation part, the fixation part comprising a porous structure (20), the fixation part further comprising a support structure (10), the porous structure (20) comprising a first porous structure (21) and a second porous structure (22), the support structure (10) comprising a first support (11) and a positioning protrusion (13), the first porous structure (21) being arranged on a side of the first support (11) facing the target bone, the second porous structure (22) being arranged on a side of the first support (11) facing the friction part (30), the positioning convex part (13) can extend into a positioning hole (32) of the friction part (30), the positioning convex part (13) is provided with a necking part (14), the shape of the positioning hole (32) is matched with that of the positioning convex part (13), the supporting structure (10) further comprises a second supporting part (12), the second supporting part (12) is arranged at the opening of the first supporting part (11) and is connected with the end part of the first supporting part (11) to form the supporting structure (10), part of the second porous structure (22) is arranged along one side surface of the second supporting part (12) facing to the target bone and protrudes inwards to form a clamping part (24), the friction part (30) is provided with a concave part (33) matched with the clamping part (24), and the necking part (14) and the inner wall of the positioning hole (32) of the friction part (30) form a first abutting relation, the clamping portion (24) and the recess portion (33) form a second abutting relation.

2. The composite insert according to claim 1, wherein the first support (11) is tapered, and the positioning protrusion (13) extends from the side of the tapered first support (11) with the smaller diameter to the side with the larger diameter.

3. The composite insert according to claim 1, wherein the fixing portion further comprises a third porous structure (23), the third porous structure (23) being arranged on a side of the second support (12) facing the friction portion (30).

4. The composite insert according to claim 1, wherein the support structure (10) further comprises a stiffening rib (15), the stiffening rib (15) being arranged on the first support (11) in a direction perpendicular to the axis of the support structure (10).

5. The composite insert according to claim 1, wherein the friction portion (30) further has a border (34), and the first porous structure (21) has an escape (25) adapted to the border (34).

6. The composite insert according to claim 1, wherein the support structure (10), the first porous structure (21) and the second porous structure (22) are made by 3D printing techniques.

7. The composite insert according to claim 1, wherein the friction portion (30) is formed by injection molding.

8. The composite insert according to claim 1, wherein the target bone is a femoral head.