CN109520837A - Nano-hardness tester loading bench special bio soft tissue moisturizing device - Google Patents
Nano-hardness tester loading bench special bio soft tissue moisturizing device Download PDFInfo
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- CN109520837A CN109520837A CN201811551691.9A CN201811551691A CN109520837A CN 109520837 A CN109520837 A CN 109520837A CN 201811551691 A CN201811551691 A CN 201811551691A CN 109520837 A CN109520837 A CN 109520837A
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- soft tissue
- nano
- loading bench
- hardness tester
- water
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- 210000004872 soft tissue Anatomy 0.000 title claims abstract description 48
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 238000012360 testing method Methods 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 4
- 229910000838 Al alloy Inorganic materials 0.000 claims description 3
- 230000003647 oxidation Effects 0.000 claims description 3
- 238000007254 oxidation reaction Methods 0.000 claims description 3
- 238000009736 wetting Methods 0.000 claims description 3
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 238000005488 sandblasting Methods 0.000 claims 1
- 239000000243 solution Substances 0.000 abstract description 9
- 230000006378 damage Effects 0.000 abstract description 7
- 239000002504 physiological saline solution Substances 0.000 abstract description 4
- 238000011056 performance test Methods 0.000 abstract description 3
- 239000000463 material Substances 0.000 description 7
- 239000012620 biological material Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000003239 periodontal effect Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/08—Investigating strength properties of solid materials by application of mechanical stress by applying steady tensile or compressive forces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/02—Details
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention provides a kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, including humidity keeping component, humidity keeping component includes holding water-bed disk, hold the top surface of water-bed disk equipped with the water tank for accommodating biologic soft tissue, the bottom surface for holding water-bed disk is equipped with block board, holds water-bed disk and is contacted by block board with the loading bench of nano-hardness tester；This kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, to realize, instillation physiological saline or ringer's solution keep tested sample wettability around tested sample in the performance test of biologic soft tissue tested sample, and do not damage to loading bench when removing tested sample.
Description
Technical field
The present invention relates to a kind of nano-hardness tester loading bench special bio soft tissue moisturizing devices.
Background technique
Nanoindentation is to add unloading to material surface with given pace by pressure head, measures indented region correlation ginseng
Number, to evaluate the technology of material mechanical performance.Based on power-displacement data of impression under nanoscale, the micro- ruler of measured material is studied
Spend mechanical property parameters.Nanoindentation is small with the requirement of measured material size, measuring force high resolution, accurately tests position
It sets, the advantages that measured material is not damaged.In the past, Nanoindentation was mainly used in measurement thin-film material, synthetic material
Etc. mechanical properties.
In recent years, Nanoindentation becomes the powerful of biology and associated materials micro-structure mechanics properties testing, by
There is extremely complex mechanism in biomaterial, and there are sizes small, light weight, the features such as be difficult to position, causes measurement difficult,
It is limited to its research effect using the test equipment of stock size, therefore select the measurement of minute yardstick practical to characterize biomaterial
Mechanical property it is particularly important.Biomaterial can be divided into sclerous tissues and soft tissue according to different mechanical properties, mineral
Bone, tooth of matter etc. belong to sclerous tissues, it will usually elasticity modulus with higher and hardness；Cartilage, muscle, skin etc. belong to
In soft tissue, fresh soft tissue would generally have high viscoplasticity.In terms of dentistry, Nanoindentation is extensive
Applied to the Research on Mechanical Properties of the biological hard tissues such as tooth, alveolar bone, but to the nano-indenter test of periodontal film dynamic performance
It studies less.But the mechanical characteristics of soft tissue and its water content are closely related, need to protect when doing the external experiment of machanics of soft tissue
Hold its moist environment in living organism.
However lack a kind of moisture-keeping container that can be used when measuring biologic soft tissue using Nanoindentation at present.And
Original technology tested sample in test is directly adhered to smooth loading bench, it is difficult to remove tested sample, be difficult to when removing
Guarantee the integrality of tested tested sample.
Summary of the invention
The object of the present invention is to provide a kind of nano-hardness tester loading bench special bio soft tissue moisturizing devices, solve existing
Lack a kind of moisture-keeping container that can be used when measuring biologic soft tissue using Nanoindentation present in technology, and original
Technology tested sample in test is directly adhered to smooth loading bench, it is difficult to the problem of removing tested sample.
The technical solution of the invention is as follows:
A kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, i.e. humidity keeping component.Humidity keeping component includes holding the bottom
Disk holds the top surface of water-bed disk equipped with the water tank for accommodating biologic soft tissue, and the bottom surface for holding water-bed disk is equipped with block board, Rong Shui
Chassis is contacted by block board with the loading bench of nano-hardness tester.
Further, block board is equipped with locating slot and several side slots, and locating slot is set to the middle part of block board, and side grooved ring is around fixed
Position slot setting.
Further, the surface of water tank uses water-wetted surface, and micropore, surface are done by carrying out surface in the surface of water tank
Coating, differential arc oxidation, sandblast technology are realized to obtain water-wetted surface.
Further, block board is using circle, and locating slot is using circle, and side slot is using semicircle.
Further, the slot bottom of water tank is equipped with frosted layer.
Further, holding water-bed disk uses circle to hold water-bed disk, and for water tank using circle, water tank and the water-bed disk of appearance are concentric
Setting.
Further, hold water-bed disk to be made of aluminium alloy.
Further, hold water-bed disk and block board uses integral structure.
Further, the use process of the nano-hardness tester loading bench special bio soft tissue moisturizing device are as follows: by detent
Plate is bonded on the objective table of loading bench, and the objective table of locating slot and the not be bonded loading bench of side slot, tested sample is adhered to Rong Shui
In the water tank on chassis, instillation wetting solution is around tested sample to keep the wettability of tested sample；After test completion, it takes
The lower nano-hardness tester loading bench special bio soft tissue moisturizing device.
The beneficial effects of the present invention are:
One, this kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, to realize in biologic soft tissue tested sample
Performance test in around tested sample instillation physiological saline or ringer's solution keep tested sample wettability, and removing
Loading bench is not damaged when tested sample, it is wet to biologic soft tissue that the solution prior art cannot achieve Nanoindentation
The problem of test under physiological status.
Two, this kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, can by be arranged side slot be easy to by
Test sample sheet is removed from loading bench, avoids the destruction to loading bench and tested sample, can guarantee to be tested tested sample after removing
Integrality solves the prior art and removes the tested sample for being bonded in loading bench more difficult, need to be prized down with blade, may be to adding
Microscope carrier and tested sample cause the problem of damage.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of nano-hardness tester loading bench special bio soft tissue moisturizing device of the embodiment of the present invention；
Fig. 2 is the structural representation of the bottom surface of nano-hardness tester loading bench special bio soft tissue moisturizing device of the embodiment of the present invention
Figure；
Fig. 3 is the knot that water tank uses water-wetted surface in embodiment nano-hardness tester loading bench special bio soft tissue moisturizing device
Structure schematic diagram；
Wherein: 1- holds water-bed disk, 2- water tank, 3- block board, 4- locating slot, the side 5- slot.
Specific embodiment
The preferred embodiment that the invention will now be described in detail with reference to the accompanying drawings.
Embodiment
A kind of nano-hardness tester loading bench special bio soft tissue moisturizing device is protected such as Fig. 1 and Fig. 2, including humidity keeping component
Wet component includes holding water-bed disk 1, and the top surface of the water-bed disk 1 of appearance is equipped with the water tank 2 for accommodating biologic soft tissue, holds water-bed disk 1
Bottom surface be equipped with block board 3, hold water-bed disk 1 and contacted by block board 3 with the loading bench of nano-hardness tester.
This kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, to realize in biologic soft tissue tested sample
Performance test in around tested sample instillation physiological saline or ringer's solution keep tested sample wettability, and removing
Loading bench is not damaged when tested sample, it is wet to biologic soft tissue that the solution prior art cannot achieve Nanoindentation
The problem of test under physiological status.
Block board 3 is equipped with locating slot 4 and several side slots 5, and locating slot 4 is set to the middle part of block board 3, and side slot 5 is around positioning
Slot 4 is arranged.This kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, can be by being arranged side slot 5, reducing and adding
The contact area of microscope carrier is easy to tested sample and removes from loading bench, avoids the destruction to loading bench, and solving the prior art will be bonded
More difficulty is removed in the tested sample of loading bench, need to be prized down with blade, loading bench and tested sample may be caused to damage
The problem of.
In embodiment, tested sample is adhered in water tank 2, humidity keeping component is placed on loading bench.Nano-hardness tester
Device during the test, instillation physiological saline or ringer's solution can keep the wet of biologic soft tissue tested sample in water tank 2
Lubricant nature, such as Fig. 3, the surface of water tank 2 are that water-wetted surface impacts test to prevent liquid accumulation on tested sample surface.
Micropore, surface covering, differential arc oxidation, sandblast technology reality are done by carrying out surface in the surface of water tank 2 in embodiment
It now obtains water-wetted surface, realizes the purpose for increasing surface hydrophilicity.
In embodiment, block board 3 is using circle, and locating slot 4 is using circle, and side slot 5 is using semicircle.The slot of water tank 2
Bottom is equipped with frosted layer.Hold water-bed disk 1 and use the water-bed disk 1 of round appearance, for water tank 2 using circle, water tank 2 and the water-bed disk 1 of appearance are same
Heart setting.Hold water-bed disk 1 to be made of aluminium alloy.Hold water-bed disk 1 and block board 3 uses integral structure, ensure that the whole of structure
Body stability and durability.
The use process of the nano-hardness tester loading bench special bio soft tissue moisturizing device are as follows: be bonded in block board 3
On the objective table of loading bench, the objective table of locating slot 4 and the not be bonded loading bench of side slot 5, it is water-bed that tested tested sample is adhered to appearance
In the water tank 2 of disk 1, instillation wetting solution is around tested tested sample to keep the wettability of tested sample；It completes to test
Afterwards, the nano-hardness tester loading bench special bio soft tissue moisturizing device is removed；To effectively avoid may to loading bench and
Tested sample causes the problem of damage.
The nano-hardness tester loading bench special bio soft tissue moisturizing device of embodiment can be avoided to loading bench and be tested
The destruction of sample can guarantee the integrality that tested sample is tested after removing.
Claims (9)
1. a kind of nano-hardness tester loading bench special bio soft tissue moisturizing device, it is characterised in that: including humidity keeping component, moisturizing
Component includes holding water-bed disk, and the top surface of the water-bed disk of appearance is equipped with the water tank for accommodating biologic soft tissue, holds the bottom surface of water-bed disk
Equipped with block board, holds water-bed disk and contacted by block board with the loading bench of nano-hardness tester.
2. nano-hardness tester loading bench special bio soft tissue moisturizing device as described in claim 1, it is characterised in that: detent
Plate is equipped with locating slot and several side slots, and locating slot is set to the middle part of block board, and side grooved ring is arranged around locating slot.
3. nano-hardness tester loading bench special bio soft tissue moisturizing device as described in claim 1, it is characterised in that: Rong Shui
The surface of slot uses water-wetted surface, and micropore, surface covering, differential arc oxidation, sandblasting skill are done by carrying out surface in the surface of water tank
Art is realized to obtain water-wetted surface.
4. nano-hardness tester loading bench special bio soft tissue moisturizing device as claimed in claim 3, it is characterised in that: detent
Plate is using circle, and locating slot is using circle, and side slot is using semicircle.
5. nano-hardness tester loading bench special bio soft tissue moisturizing device according to any one of claims 1-4, feature
Be: the slot bottom of water tank is equipped with frosted layer.
6. nano-hardness tester loading bench special bio soft tissue moisturizing device as claimed in claim 5, it is characterised in that: Rong Shui
Chassis uses the water-bed disk of round appearance, and using circle, water tank is arranged concentrically water tank with bottom disk is held.
7. nano-hardness tester loading bench special bio soft tissue moisturizing device as described in claim 1, it is characterised in that: Rong Shui
Chassis is made of aluminium alloy.
8. nano-hardness tester loading bench special bio soft tissue moisturizing device as described in claim 1, it is characterised in that: Rong Shui
Chassis and block board use integral structure.
9. nano-hardness tester loading bench special bio soft tissue moisturizing device as described in claim 1, it is characterised in that: this is received
The use process of rice impression instrument loading bench special bio soft tissue moisturizing device are as follows: block board is bonded in the objective table of loading bench
On, the objective table of locating slot and the not be bonded loading bench of side slot, tested sample is adhered in the water tank for holding water-bed disk, is tested tested
Instillation wetting solution is around sample to keep the wettability of tested sample；After test completion, nano-hardness tester load is removed
Platform special bio soft tissue moisturizing device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811551691.9A CN109520837A (en) | 2018-12-19 | 2018-12-19 | Nano-hardness tester loading bench special bio soft tissue moisturizing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811551691.9A CN109520837A (en) | 2018-12-19 | 2018-12-19 | Nano-hardness tester loading bench special bio soft tissue moisturizing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109520837A true CN109520837A (en) | 2019-03-26 |
Family
ID=65796609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811551691.9A Pending CN109520837A (en) | 2018-12-19 | 2018-12-19 | Nano-hardness tester loading bench special bio soft tissue moisturizing device |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2262707Y (en) * | 1996-07-31 | 1997-09-17 | 山东省千佛山医院 | Pathological tissue embedding box |
| CN102338714A (en) * | 2011-03-07 | 2012-02-01 | 北京工业大学 | Anisotropic nanometer press-in test table of biological soft tissues and method for performing nanometer press-in experiment by using anisotropic nanometer press-in test table |
| CN103543065A (en) * | 2013-10-14 | 2014-01-29 | 北京工业大学 | Ice nano-grade indentation sample bench and related experiment method |
| CN103575591A (en) * | 2013-10-14 | 2014-02-12 | 北京工业大学 | Articular cartilage microstructure nanoindentation inlaying and water-retaining sample stage and experiment method |
| CN205483873U (en) * | 2016-01-25 | 2016-08-17 | 中国科学院声学研究所东海研究站 | Biological tissue elasticity measuring apparatu |
| CN209894597U (en) * | 2018-12-19 | 2020-01-03 | 南京医科大学附属口腔医院 | Special biological soft tissue moisturizing device for nano-indentation instrument loading platform |
-
2018
- 2018-12-19 CN CN201811551691.9A patent/CN109520837A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2262707Y (en) * | 1996-07-31 | 1997-09-17 | 山东省千佛山医院 | Pathological tissue embedding box |
| CN102338714A (en) * | 2011-03-07 | 2012-02-01 | 北京工业大学 | Anisotropic nanometer press-in test table of biological soft tissues and method for performing nanometer press-in experiment by using anisotropic nanometer press-in test table |
| CN103543065A (en) * | 2013-10-14 | 2014-01-29 | 北京工业大学 | Ice nano-grade indentation sample bench and related experiment method |
| CN103575591A (en) * | 2013-10-14 | 2014-02-12 | 北京工业大学 | Articular cartilage microstructure nanoindentation inlaying and water-retaining sample stage and experiment method |
| CN205483873U (en) * | 2016-01-25 | 2016-08-17 | 中国科学院声学研究所东海研究站 | Biological tissue elasticity measuring apparatu |
| CN209894597U (en) * | 2018-12-19 | 2020-01-03 | 南京医科大学附属口腔医院 | Special biological soft tissue moisturizing device for nano-indentation instrument loading platform |
Non-Patent Citations (1)
| Title |
|---|
| 刘志远 等: "基于纳米压痕法的关节软骨保湿测量技术", 《医用生物力学》, vol. 26, no. 5, 31 October 2011 (2011-10-31), pages 408 - 412 * |
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