CN109512550B - Artificial crystal with composite structure - Google Patents
Artificial crystal with composite structure Download PDFInfo
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- CN109512550B CN109512550B CN201910035582.XA CN201910035582A CN109512550B CN 109512550 B CN109512550 B CN 109512550B CN 201910035582 A CN201910035582 A CN 201910035582A CN 109512550 B CN109512550 B CN 109512550B
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- Prior art keywords
- layer
- lens
- pmma
- edge
- silica gel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
Abstract
The invention provides an artificial lens with a composite structure. According to the technical scheme, firstly, a hydrophilic acrylate layer and a hyaluronic acid sodium layer are utilized to coat the PMMA material, the edge of the PMMA material is sealed by a hydrophobic acrylate ring, and in the sealed space, the hard PMMA material is prevented from being contacted with eye tissues, and meanwhile, good light transmittance and refractive index can be kept; on the basis, the composite material layer, the silica gel layer and the hydrogel layer form a composite structure, the flexible silica gel and the hydrogel are used for sealing, and the lower layer of silica gel is turned upwards to form a wrapping edge, so that good sealing performance is guaranteed. By applying the invention, the tensile strength of the artificial lens can be improved on the premise of not influencing the optical performance, and the direct contact between a hard structure and eye tissues is avoided, so that the use is more comfortable.
Description
Technical Field
The invention relates to the technical field of artificial lenses, in particular to an artificial lens with a composite structure.
Background
Intraocular lenses, also known as intraocular lenses, are precision optical components that are surgically implanted into the eye to replace the removed, self-opacified lens. The main components of human crystals are protein and water, which can cause fogging or clouding due to aging, and the fogging crystals can block light and images from being projected onto the retina. The phenomenon of crystal atomization can be caused by eye damage, certain diseases and even certain drug treatments; according to statistics, more than 90% of cataract cases are also caused by the essential aging process of human beings, namely, the eye crystals become turbid and then the vision is affected, the mechanism is not clear, and the drug treatment has not been developed in a breakthrough manner so far. The only truly effective treatment for cataracts is surgical treatment, which involves removing the lens that has become opaque and replacing it with an artificial lens, known as an intraocular lens. Intraocular lens implantation is the most effective means of treating cataracts, with thousands of cataract patients achieving good vision through this safe and effective surgical procedure.
An intraocular lens is a lens with a fixed diopter and is synthesized by artificial materials, and the materials for manufacturing the intraocular lens have the following characteristics: (1) the optical property is good, the refractive index is high, and the visible light transmittance is high (the light transmittance is more than 90%); (2) the weight is light, and the tensile resistance is strong; (3) the physical and chemical properties in eyes are stable, the durability is strong, and the biological degradation effect is achieved; (4) no toxicity, no inflammation and no carcinogenicity; (5) no antigenicity; (6) the processing is easy. In the prior art, the artificial lens is mostly made of a single-layer PMMA material, the hardness of the artificial lens is high, but the tensile strength is insufficient, so that certain damage risk exists on eye tissues in the using process, and the low tensile strength is not beneficial to long-term use.
Disclosure of Invention
The invention aims to provide an artificial lens with a composite structure aiming at the technical defects of the prior art, and aims to solve the technical problems that the artificial lens made of a single-layer PMMA material in the prior art is high in hardness and can damage eye tissues.
Another technical problem to be solved by the present invention is how to increase the tensile strength of the intraocular lens.
In order to achieve the technical purpose, the invention adopts the following technical scheme:
an artificial lens with a composite structure comprises a lens sheet, lens loops, hooks, a silica gel layer, a hydrogel layer, a composite material layer, a wrapping edge, a hydrophilic acrylate layer, a sodium hyaluronate layer, a PMMA layer and a hydrophobic acrylate ring, wherein the lens sheet is connected with at least two lens loops, and the tail end of each lens loop is provided with a hook; the crystal sheet comprises a silica gel layer, a hydrogel layer, a composite material layer and a covered edge, wherein the silica gel layer is covered on the upper surface of the composite material layer, the silica gel layer is covered on the lower surface of the composite material layer, the covered edge is arranged at the edge of the silica gel layer, and the covered edge is turned upwards and pressed on the edge of the upper end of the silica gel layer; the composite material layer comprises a hydrophilic acrylate layer, a sodium hyaluronate layer, a PMMA layer and a hydrophobic acrylate ring, wherein the hydrophilic acrylate layer is attached to the upper surface of the PMMA layer, the sodium hyaluronate layer is attached to the lower surface of the PMMA layer, and the hydrophobic acrylate ring is encircled at the edge of the PMMA layer.
Preferably, the hydrophilic acrylate layer, the sodium hyaluronate layer and the PMMA layer are equal in thickness.
Preferably, the hydrophilic acrylate layer, the sodium hyaluronate layer and the hydrophobic acrylate ring jointly enclose a closed space, and the PMMA layer is positioned in the closed space.
Preferably, there are two of the lens haptics, and the lens haptics are C-shaped haptics.
Preferably, the crystalline sheet is circular; the number of the crystal loop is two, the two crystal loops are in a centrosymmetric relation, and the symmetric centers of the two crystal loops are the circle centers of the crystal sheets.
The invention provides an artificial lens with a composite structure. According to the technical scheme, firstly, a hydrophilic acrylate layer and a hyaluronic acid sodium layer are utilized to coat the PMMA material, the edge of the PMMA material is sealed by a hydrophobic acrylate ring, and in the sealed space, the hard PMMA material is prevented from being contacted with eye tissues, and meanwhile, good light transmittance and refractive index can be kept; on the basis, the composite material layer, the silica gel layer and the hydrogel layer form a composite structure, the flexible silica gel and the hydrogel are used for sealing, and the lower layer of silica gel is turned upwards to form a wrapping edge, so that good sealing performance is guaranteed. By applying the invention, the tensile strength of the artificial lens can be improved on the premise of not influencing the optical performance, and the direct contact between a hard structure and eye tissues is avoided, so that the use is more comfortable.
Drawings
FIG. 1 is a schematic structural view of the present invention as a whole;
FIG. 2 is a cross-sectional view of a crystal sheet in the present invention;
FIG. 3 is a cross-sectional view of a composite layer of the present invention;
in the figure:
1. crystal sheet 2, crystal loop 3, hook 4, silicone gel layer
5. Hydrogel layer 6, composite material layer 7, edge cover 8 and hydrophilic acrylate layer
9. A sodium hyaluronate layer 10, a PMMA layer 11, and a hydrophobic acrylate ring.
Detailed Description
Hereinafter, specific embodiments of the present invention will be described in detail. Well-known structures or functions may not be described in detail in the following embodiments in order to avoid unnecessarily obscuring the details. Approximating language, as used herein in the following examples, may be applied to identify quantitative representations that could permissibly vary in number without resulting in a change in the basic function. Unless defined otherwise, technical and scientific terms used in the following examples have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
Example 1
An intraocular lens with a composite structure, as shown in fig. 1-3, comprises a lens sheet 1, lens loops 2, hooks 3, a silicone gel layer 4, a hydrogel layer 5, a composite material layer 6, a wrapping 7, a hydrophilic acrylate layer 8, a sodium hyaluronate layer 9, a PMMA layer 10, and hydrophobic acrylate rings 11, wherein at least two lens loops 2 are connected to the lens sheet 1, and a hook 3 is arranged at the end of each lens loop 2; the crystal sheet 1 comprises a silica gel layer 4, a hydrogel layer 5, a composite material layer 6 and an edge covering 7, wherein the hydrogel layer 5 covers the upper surface of the composite material layer 6, the silica gel layer 4 covers the lower surface of the composite material layer 6, the edge of the silica gel layer 4 is provided with the edge covering 7, and the edge covering 7 is turned upwards and pressed on the edge of the upper end of the hydrogel layer 5; the composite material layer 6 comprises a hydrophilic acrylate layer 8, a sodium hyaluronate layer 9, a PMMA layer 10 and a hydrophobic acrylate ring 11, wherein the hydrophilic acrylate layer 8 is attached to the upper surface of the PMMA layer 10, the sodium hyaluronate layer 9 is attached to the lower surface of the PMMA layer 10, and the hydrophobic acrylate ring 11 is encircled at the edge of the PMMA layer 10.
Example 2
An intraocular lens with a composite structure, as shown in fig. 1-3, comprises a lens sheet 1, lens loops 2, hooks 3, a silicone gel layer 4, a hydrogel layer 5, a composite material layer 6, a wrapping 7, a hydrophilic acrylate layer 8, a sodium hyaluronate layer 9, a PMMA layer 10, and hydrophobic acrylate rings 11, wherein at least two lens loops 2 are connected to the lens sheet 1, and a hook 3 is arranged at the end of each lens loop 2; the crystal sheet 1 comprises a silica gel layer 4, a hydrogel layer 5, a composite material layer 6 and an edge covering 7, wherein the hydrogel layer 5 covers the upper surface of the composite material layer 6, the silica gel layer 4 covers the lower surface of the composite material layer 6, the edge of the silica gel layer 4 is provided with the edge covering 7, and the edge covering 7 is turned upwards and pressed on the edge of the upper end of the hydrogel layer 5; the composite material layer 6 comprises a hydrophilic acrylate layer 8, a sodium hyaluronate layer 9, a PMMA layer 10 and a hydrophobic acrylate ring 11, wherein the hydrophilic acrylate layer 8 is attached to the upper surface of the PMMA layer 10, the sodium hyaluronate layer 9 is attached to the lower surface of the PMMA layer 10, and the hydrophobic acrylate ring 11 is encircled at the edge of the PMMA layer 10. Wherein, the thickness of the hydrophilic acrylate layer 8, the thickness of the sodium hyaluronate layer 9 and the thickness of the PMMA layer 10 are equal. The hydrophilic acrylate layer 8, the sodium hyaluronate layer 9 and the hydrophobic acrylate ring 11 jointly enclose a closed space, and the PMMA layer 10 is positioned in the closed space. The number of the crystal loop 2 is two, and the crystal loop 2 is a C-shaped loop. The crystal sheet 1 is circular; the number of the crystal loop 2 is two, the two crystal loop 2 are in a centrosymmetric relation, and the symmetric center of the two crystal loop 2 is the center of a circle of the crystal sheet 1.
The embodiments of the present invention have been described in detail, but the description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention. Any modification, equivalent replacement, and improvement made within the scope of the application of the present invention should be included in the protection scope of the present invention.
Claims (5)
1. An artificial lens with a composite structure is characterized by comprising a lens sheet (1), lens loops (2), hooks (3), a silica gel layer (4), a hydrogel layer (5), a composite material layer (6), a wrapping edge (7), a hydrophilic acrylate layer (8), a sodium hyaluronate layer (9), a PMMA layer (10) and hydrophobic acrylate rings (11), wherein at least two lens loops (2) are connected to the lens sheet (1), and the hooks (3) are arranged at the tail end of each lens loop (2); the crystal sheet (1) comprises a silica gel layer (4), a hydrogel layer (5), a composite material layer (6) and a covered edge (7), wherein the hydrogel layer (5) is coated on the upper surface of the composite material layer (6), the silica gel layer (4) is coated on the lower surface of the composite material layer (6), the covered edge (7) is arranged on the edge of the silica gel layer (4), and the covered edge (7) is turned upwards and pressed on the edge of the upper end of the hydrogel layer (5); the composite material layer (6) comprises a hydrophilic acrylate layer (8), a sodium hyaluronate layer (9), a PMMA layer (10) and a hydrophobic acrylate ring (11), wherein the hydrophilic acrylate layer (8) is attached to the upper surface of the PMMA layer (10), the sodium hyaluronate layer (9) is attached to the lower surface of the PMMA layer (10), and the hydrophobic acrylate ring (11) is encircled at the edge of the PMMA layer (10).
2. Intraocular lens of composite construction according to claim 1, characterised in that the hydrophilic acrylate layer (8), the sodium hyaluronate layer (9) and the PMMA layer (10) are of equal thickness.
3. Intraocular lens of composite construction according to claim 1, characterised in that the hydrophilic acrylate layer (8), the sodium hyaluronate layer (9) and the hydrophobic acrylate ring (11) together enclose a closed space in which the PMMA layer (10) is located.
4. A composite construction intraocular lens according to claim 1, characterised in that there are two of said haptics (2), said haptics (2) being C-shaped haptics.
5. A composite structure intraocular lens according to claim 1, characterised in that the lens sheet (1) is circular; the number of the crystal loop (2) is two, the two crystal loop (2) are in a centrosymmetric relation, and the symmetric center of the two crystal loop (2) is the circle center of the crystal sheet (1).
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CN109512550B true CN109512550B (en) | 2020-11-06 |
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Family Cites Families (6)
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US4919663A (en) * | 1987-08-24 | 1990-04-24 | Grendahl Dennis T | Laminated zone of focus artificial hydrogel lens |
US6702853B1 (en) * | 2000-10-02 | 2004-03-09 | Gholam A. Peyman | Intraocular lens system utilizing an adhesive and method for implanting the same |
US6695880B1 (en) * | 2000-10-24 | 2004-02-24 | Johnson & Johnson Vision Care, Inc. | Intraocular lenses and methods for their manufacture |
CA2552122A1 (en) * | 2003-12-29 | 2005-07-21 | Advanced Medical Optics, Inc. | Intraocular lenses having a visible light-selective-transmissive-region |
KR101538026B1 (en) * | 2006-06-12 | 2015-07-22 | 하이 퍼포먼스 옵틱스 인코퍼레이티드 | Color balanced ophthalmic system with selective light inhibition |
CN107212949B (en) * | 2017-07-12 | 2019-05-14 | 无锡蕾明视康科技有限公司 | A kind of multifocal intraocular lenses |
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