CN109498869A - A kind of medicinal blood dialysis urea real-time monitoring sensing device - Google Patents

A kind of medicinal blood dialysis urea real-time monitoring sensing device Download PDF

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Publication number
CN109498869A
CN109498869A CN201910016773.1A CN201910016773A CN109498869A CN 109498869 A CN109498869 A CN 109498869A CN 201910016773 A CN201910016773 A CN 201910016773A CN 109498869 A CN109498869 A CN 109498869A
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CN
China
Prior art keywords
outer housing
sensing device
time monitoring
probe
urea
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Pending
Application number
CN201910016773.1A
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Chinese (zh)
Inventor
郑雪梅
刘洪菊
魏亿慧
宋春美
陶克波
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Individual
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Individual
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Priority to CN201910016773.1A priority Critical patent/CN109498869A/en
Publication of CN109498869A publication Critical patent/CN109498869A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607Regulation parameters
    • A61M1/3609Physical characteristics of the blood, e.g. haematocrit, urea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a kind of medicinal blood dialysis urea real-time monitoring sensing devices, are related to technical field of medical equipment, change mainly for solving the problems, such as accurately to monitor urea content in blood in real time;The monitoring sensor, including outer housing and the sensing device being set to inside outer housing, outer housing is internally provided with installation plate, plate is installed by outer housing inside division into upper chamber and reservoir chamber, the sensing device includes detection probe, external interface and signal adapter, inlet tube and outlet tube are provided on the corresponding side wall of the two of the outer housing, the detection probe includes outer framework and the multiple enzyme field-effect tube and multiple ion field-effect tube that are installed on outer framework, it is provided with flow velocity probe in the inlet tube, flow probe is installed in outlet tube.The configuration of the present invention is simple can monitor the content of urea in serum in real time, and monitoring is comprehensively and accurate, and easy to operate, practicability is stronger.

Description

A kind of medicinal blood dialysis urea real-time monitoring sensing device
Technical field
The present invention relates to technical field of medical equipment, specifically a kind of medicinal blood dialysis urea real-time monitoring sensing device.
Background technique
Haemodialysis is one of acute or chronic renal failure kidneys of patients Replacement Therapy.It is by drawing internal blood Flow to it is external, through one by the dialyzer that forms without several hollow fibres, blood electrolyte similar with concentration containing body is molten Liquid (dialyzate) carries out mass exchange inside and outside hollow fibre one by one, through disperse/convection current, remove intracorporal metabolic waste, Maintain electrolyte and acid-base balance;Moisture excessive in vivo is removed simultaneously, and will be by the whole process of the blood recovery purified Referred to as haemodialysis.
The detection of urea is all made of and is drained to vitro detection in blood at present, can not real time monitoring, so can not be real-time The changes of contents of urea in accurate monitoring blood.
Summary of the invention
The purpose of the present invention is to provide a kind of medicinal blood dialysis urea real-time monitoring sensing devices, can not be real-time with solution In accurate monitoring blood the problem of urea content variation.
To achieve the above object, the invention provides the following technical scheme:
A kind of medicinal blood dialysis urea real-time monitoring sensing device, including outer housing and the induction being set to inside outer housing dress It sets, outer housing is internally provided with installation plate, installs plate for outer housing inside division into upper chamber and reservoir chamber, the sense Answering device includes detection probe, external interface and signal adapter, and the detection probe is two and is fixed on installation plate Bottom end, external interface and signal adapter are fixed on installation plate upper end and signal adapter input terminal and two detection probes are defeated Outlet is electrically connected, and there are two the connectivity ports being separately connected to power and transmit signal for setting on external interface, described outer It is provided with inlet tube and outlet tube on the corresponding side wall of the two of shell, the detection probe includes outer framework and is installed on outer framework Multiple enzyme field-effect tube and multiple ion field-effect tube, be provided with flow velocity probe in the inlet tube, be equipped in outlet tube The output end of flow probe, flow velocity probe and flow probe is connected to signal adapter.
Based on the above technical solution, the present invention also provides following optional technical solutions:
In a kind of optinal plan: multiple enzyme field-effect tube and multiple ion field-effect tube are installed in upright state and sequence.
In a kind of optinal plan: being connected with connecting wire on the connectivity port, the end of connecting wire is provided with slotting Connect end.
In a kind of optinal plan: the outer housing top end opening is arranged and is equipped with top cover with matching, installs Wall slip is cooperatively connected in the avris and outer housing of plate, and installation plate upper surface is provided with two connection vertical bars, two connections Vertical bar upper end is fixedly connected on top cover face.
In a kind of optinal plan: the take-up pulley to wind connecting wire is installed on the top cover.
In a kind of optinal plan: being provided with side chute from top to bottom, installation in side chute on the outer housing inner wall There is the connection sliding block being slidably fastened therewith, connection sliding block end side is fixedly connected with installation plate avris.
In a kind of optinal plan: the connection vertical bar is hollow setting and connecting wire passes through inside connection vertical bar.
Compared to the prior art, beneficial effects of the present invention are as follows:
1, detection accuracy can be increased by the setting mutual cooperation of multiple enzyme field-effect tube and ion field-effect tube;
2, velocity of blood flow and flow are detected by flow velocity probe and flow probe respectively, can detect more fully, further in real time Monitor haemodialysis urea content;
3, the configuration of the present invention is simple can monitor the content of urea in serum in real time, and monitoring is comprehensively and accurate, easy to operate, practical Property is stronger.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention.
Fig. 2 is the structural schematic diagram of detection probe in the present invention.
Appended drawing reference annotation: outer housing 1, inlet tube 2, outlet tube 3, detection probe 4, installation plate 5, external interface 6, letter Number converter 7, connectivity port 8, connecting wire 9, take-up pulley 10, grafting end 11, outer framework 12, enzyme field-effect tube 13, ion Field-effect tube 14, flow velocity probe 15, flow probe 16, top cover 17, connection vertical bar 18, side chute 19, connection sliding block 20.
Specific embodiment
Following embodiment can be described in detail the present invention in conjunction with attached drawing, in attached drawing or explanation, similar or identical part Using identical label, and in practical applications, shape, thickness or the height of each component can be expanded or shunk.Institute of the present invention Each embodiment enumerated is only to illustrate the present invention, is not used to limit the scope of the present invention.It is made for the present invention any aobvious And modification easy to know or change are without departure from spirit and scope of the invention.
Embodiment 1
Please refer to Fig. 1 and 2, in the embodiment of the present invention, a kind of medicinal blood is dialysed urea real-time monitoring sensing device, including outer housing 1 and the sensing device that is set to outer housing 1 inside, outer housing 1 be internally provided with installation plate 5, plate 5 is installed by outer housing 1 For inside division at upper chamber and reservoir chamber, the sensing device includes detection probe 4, external interface 6 and signal adapter 7, The detection probe 4 is two and is fixed on the bottom end of installation plate 5, and external interface 6 and signal adapter 7 are fixed on mounting plate 5 upper end of part and 7 input terminal of signal adapter and two 4 output ends of detection probe are electrically connected, on external interface 6 there are two settings It is separately connected the connectivity port 8 to power and transmit signal, connecting wire 9 is connected on connectivity port 8, connecting wire 9 End is provided with grafting end 11, is provided with inlet tube 2 and outlet tube 3, the detection on the corresponding side wall of the two of the outer housing 1 Probe 4 includes outer framework 12 and the multiple enzyme field-effect tube 13 and multiple ion field-effect tube 14 that are installed on outer framework 12, more A enzyme field-effect tube 13 and multiple ion field-effect tube 14 are installed in upright state and sequence, are provided in the inlet tube 2 Flow velocity probe 15, is equipped with flow probe 16 in outlet tube 3, and the output end of flow velocity probe 15 and flow probe 16 is connected to signal Converter 7, enzyme field-effect tube 13 detects the content of urea in blood using urease, and ion field-effect tube 14 is for detecting The data that population of ions changes and can detect to enzyme field-effect tube 13 be modified, and further increase the effect of detection, and more The setting of a enzyme field-effect tube 13 and ion field-effect tube 14 can increase detection accuracy, and flow velocity probe 15 and flow probe 16 Velocity of blood flow and flow are detected respectively, and the data that detection probe 4, flow velocity probe 15 and flow probe 16 detect are through signal adapter 7 are converted into uniformly showing through the output of connectivity port 8 to external equipment after electric signal, further monitor haemodialysis urine in real time Element.
Embodiment 2
The embodiment of the present invention difference from example 1 is that: 1 top end opening of outer housing setting and phase therewith is installed The top cover 17 of cooperation is equipped with the take-up pulley 10 to wind connecting wire 9 on the top cover 17, install the avris of plate 5 with Wall slip is cooperatively connected in outer housing 1, specifically, being provided with side chute 19 from top to bottom on 1 inner wall of the outer housing, breaks away The connection sliding block 20 being slidably fastened therewith is installed, 20 end side of connection sliding block is fixedly connected with installation 5 avris of plate, installation in slot 19 5 upper surface of plate is provided with two connection vertical bars 18, and two 18 upper ends of connection vertical bar are fixedly connected on 17 lower end surface of top cover, described Vertical bar 18 is connected as hollow setting and connecting wire 9 passes through inside connection vertical bar 18 in order to protect connecting wire 9, passes through top cover 17 and installation plate 5 and 1 side wall of outer housing sliding be equipped with may make sensing device take out and facilitate maintenance.
The above, the only specific embodiment of the disclosure, but the protection scope of the disclosure is not limited thereto, it is any Those familiar with the art can easily think of the change or the replacement in the technical scope that the disclosure discloses, and should all contain It covers within the protection scope of the disclosure.Therefore, the protection scope of the disclosure should be subject to the protection scope in claims.

Claims (7)

  1. The urea real-time monitoring sensing device 1. a kind of medicinal blood is dialysed including outer housing (1) and is set to outer housing (1) inside Sensing device, outer housing (1) are internally provided with installation plate (5), install plate (5) for outer housing (1) inside division into epicoele Room and reservoir chamber, the sensing device include detection probe (4), external interface (6) and signal adapter (7), and feature exists In the detection probe (4) is two and is fixed on the bottom end of installation plate (5), external interface (6) and signal adapter (7) It is fixed on installation plate (5) upper end and signal adapter (7) input terminal and two detection probe (4) output ends is electrically connected, outside It is arranged on connection interface (6) there are two the connectivity port (8) being separately connected to power and transmit signal, the outer housing (1) It is provided with inlet tube (2) and outlet tube (3) on two corresponding side walls, the detection probe (4) includes outer framework (12) and is installed on Multiple enzyme field-effect tube (13) and multiple ion field-effect tube (14) on outer framework (12), the inlet tube (2) is interior to be provided with Flow velocity probe (15), outlet tube (3) is interior to be equipped with flow probe (16), the output end of flow velocity probe (15) and flow probe (16) It is connected to signal adapter (7).
  2. The urea real-time monitoring sensing device 2. medicinal blood according to claim 1 is dialysed, which is characterized in that multiple enzyme field effects (13) and multiple ion field-effect tube (14) should be managed to install in upright state and sequence.
  3. The urea real-time monitoring sensing device 3. medicinal blood according to claim 1 is dialysed, which is characterized in that the connecting pin It is connected with connecting wire (9) on mouth (8), the end of connecting wire (9) is provided with grafting end (11).
  4. The urea real-time monitoring sensing device 4. medicinal blood according to claim 3 is dialysed, which is characterized in that the outer housing (1) top end opening is arranged and is equipped with top cover with matching (17), installs the avris and outer housing (1) inner wall of plate (5) Sliding is cooperatively connected, and installation plate (5) upper surface is provided with two connection vertical bars (18), and two connection vertical bar (18) upper ends are fixed It is connected to top cover (17) lower end surface.
  5. The urea real-time monitoring sensing device 5. medicinal blood according to claim 4 is dialysed, which is characterized in that the top cover (17) take-up pulley (10) to wind connecting wire (9) is installed on.
  6. The urea real-time monitoring sensing device 6. medicinal blood according to claim 4 is dialysed, which is characterized in that the outer housing (1) it is provided with side chute (19) from top to bottom on inner wall, the connection sliding block being slidably fastened therewith is installed in side chute (19) (20), connection sliding block (20) end side is fixedly connected with installation plate (5) avris.
  7. The urea real-time monitoring sensing device 7. medicinal blood according to claim 4 is dialysed, which is characterized in that the connection is perpendicular Bar (18) is hollow setting and connecting wire (9) passes through connection vertical bar (18) inside.
CN201910016773.1A 2019-01-08 2019-01-08 A kind of medicinal blood dialysis urea real-time monitoring sensing device Pending CN109498869A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910016773.1A CN109498869A (en) 2019-01-08 2019-01-08 A kind of medicinal blood dialysis urea real-time monitoring sensing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910016773.1A CN109498869A (en) 2019-01-08 2019-01-08 A kind of medicinal blood dialysis urea real-time monitoring sensing device

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CN109498869A true CN109498869A (en) 2019-03-22

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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1034432A (en) * 1988-01-08 1989-08-02 大洋渔业株式会社 Biology sensor
US4909921A (en) * 1988-02-10 1990-03-20 Nec Corporation Electrochemical sensor facilitating repeated measurement
US5858186A (en) * 1996-12-20 1999-01-12 The Regents Of The University Of California Urea biosensor for hemodialysis monitoring
US20080099331A1 (en) * 2006-01-12 2008-05-01 Chung Yuan Christian University Solid-state urea biosensor and its data acquisition system
CN104605864A (en) * 2015-01-23 2015-05-13 吴晔旻 Hematodialysis urea real-time monitoring sensor
CN204618247U (en) * 2015-01-23 2015-09-09 吴晔旻 Hemodialysis carbamide real-time monitoring sensing device
CN204924382U (en) * 2015-05-23 2015-12-30 肖孝宾 A two level sensor for urea case
CN205538796U (en) * 2016-04-15 2016-08-31 温州瓯科科技有限公司 Electrical capacitance tomography system sensor
CN107807093A (en) * 2016-09-09 2018-03-16 美敦力公司 Fluid sensor equipment
CN108627502A (en) * 2017-03-17 2018-10-09 株式会社理光 Chemiluminescence analysis device, apparatus for purifying blood and blood purification system

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1034432A (en) * 1988-01-08 1989-08-02 大洋渔业株式会社 Biology sensor
US4909921A (en) * 1988-02-10 1990-03-20 Nec Corporation Electrochemical sensor facilitating repeated measurement
US5858186A (en) * 1996-12-20 1999-01-12 The Regents Of The University Of California Urea biosensor for hemodialysis monitoring
US20080099331A1 (en) * 2006-01-12 2008-05-01 Chung Yuan Christian University Solid-state urea biosensor and its data acquisition system
CN104605864A (en) * 2015-01-23 2015-05-13 吴晔旻 Hematodialysis urea real-time monitoring sensor
CN204618247U (en) * 2015-01-23 2015-09-09 吴晔旻 Hemodialysis carbamide real-time monitoring sensing device
CN204924382U (en) * 2015-05-23 2015-12-30 肖孝宾 A two level sensor for urea case
CN205538796U (en) * 2016-04-15 2016-08-31 温州瓯科科技有限公司 Electrical capacitance tomography system sensor
CN107807093A (en) * 2016-09-09 2018-03-16 美敦力公司 Fluid sensor equipment
CN108627502A (en) * 2017-03-17 2018-10-09 株式会社理光 Chemiluminescence analysis device, apparatus for purifying blood and blood purification system

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Application publication date: 20190322

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