CN109490178B - Flow cytometer and lens adjusting mechanism thereof - Google Patents
Flow cytometer and lens adjusting mechanism thereof Download PDFInfo
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- CN109490178B CN109490178B CN201811604089.7A CN201811604089A CN109490178B CN 109490178 B CN109490178 B CN 109490178B CN 201811604089 A CN201811604089 A CN 201811604089A CN 109490178 B CN109490178 B CN 109490178B
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- 230000000670 limiting effect Effects 0.000 claims abstract description 15
- 229910000831 Steel Inorganic materials 0.000 claims description 26
- 239000010959 steel Substances 0.000 claims description 26
- 230000006835 compression Effects 0.000 claims description 21
- 238000007906 compression Methods 0.000 claims description 21
- 210000004907 gland Anatomy 0.000 claims description 5
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000003754 machining Methods 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 238000009434 installation Methods 0.000 description 4
- 230000007547 defect Effects 0.000 description 3
- 238000000684 flow cytometry Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
- G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
- G02B7/023—Mountings, adjusting means, or light-tight connections, for optical elements for lenses permitting adjustment
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- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Lens Barrels (AREA)
- Mounting And Adjusting Of Optical Elements (AREA)
Abstract
The invention discloses a flow cytometer and a lens adjusting mechanism thereof. The lens adjustment mechanism includes: a lens barrel base and a flow Chi De for mounting a flow cell; the lens assembly comprises a lens barrel positioned on a lens barrel base and a lens arranged on the lens barrel, wherein the lens barrel is arranged on the lens barrel base, and after the flow type pool is arranged on the flow type pool base, the center of the lens and the center of the flow type pool are positioned on the same axis; the circumferential limiting component is abutted against the lens barrel to prevent the radial runout and circumferential rotation of the lens barrel; and the axial adjusting assembly is abutted against the lens barrel to adjust the axial position of the lens barrel. Through setting up circumference spacing subassembly can eliminate and prevent lens cone radial runout and circumference rotation, guaranteed the accuracy of flow type pond and focus lens location, improve lens adjustment mechanism's stability simultaneously, lens adjustment mechanism processing cost is low, adjustment performance is reliable, the precision is high.
Description
Technical Field
The invention relates to the technical field of optical adjustment of flow cytometry, in particular to a flow cytometer and a lens adjusting mechanism thereof.
Background
The flow cytometer is a device for automatically analyzing and sorting cells or biological particles, can rapidly detect, store and display a series of important biophysical and biochemical characteristic parameters of dispersed cells suspended in liquid, can sort out designated cell subsets according to a preselected parameter range, and is widely applied to basic researches of cell biology, immunology, physiology, molecular biology and the like, and meanwhile, is also applied to clinical diagnosis of medicine, environmental detection and the like. The optical system is one of the core systems of the flow cytometry, and the cells dyed by the specific fluorescence emit fluorescence after being irradiated and excited by a proper light source, and the fluorescence is collected and detected to finally obtain relevant parameters and data of the cells.
For the flow cytometer, the center of the focusing lens and the center of the flow cell are required to be located on the same axis, and meanwhile, the axial position of the focus of the polychromatic laser beam is adjustable and positionable, so that the accuracy and stability of the focusing position of the laser beam are ensured.
The existing focusing lens adjusting mechanism comprises a round lens barrel and a round base, the round lens barrel can axially move in the round base through precision machining, but the round lens barrel is not limited in the circumferential direction of the round lens barrel, the lens barrel can circumferentially rotate in a round groove to further influence the stability and the centering of an optical path, and meanwhile, the machining difficulty is high and the cost is high. The chinese patent with publication No. CN205665453U discloses a combined adjuster for a flow cell and a focusing lens, the chinese patent with publication No. CN205665592U discloses an adjustable angle combined adjuster for a flow cytometer, the combined adjusters disclosed in CN205665453U and CN205665592U can realize axial position adjustment of the focusing lens, but a lens sleeve seat for mounting the focusing lens is not constrained in radial direction, radial runout is easy to occur, and at the same time, the lens sleeve seat is subject to axial position adjustment of the combined adjuster, but axial runout also occurs, so that the center of a flow cell and the center of the focusing lens are not on the same axis, and accuracy and stability of a focusing position of a laser beam are affected.
Disclosure of Invention
In order to overcome the defects of the prior art, one of the purposes of the invention is to provide a lens adjusting mechanism of a flow cytometer, which can effectively eliminate radial runout and circumferential rotation of a lens barrel, has high stability, and can realize the axial position adjustment of the lens barrel, ensure that the center line of a flow cell and the center of a focusing lens are on the same axis, and has high accuracy and stability of the focusing position of a laser beam.
Another object of the present invention is to provide a flow cytometer using the above-described lens adjustment mechanism.
The invention adopts the following technical scheme:
a lens adjustment mechanism for a flow cytometer, comprising:
A lens barrel base and a flow Chi De for mounting a flow cell;
The lens assembly comprises a lens barrel positioned on a lens barrel base and a lens arranged on the lens barrel, wherein the lens barrel is arranged on the lens barrel base, and after a flow type pool is arranged on the flow type pool base, the center of the lens and the center line of the flow type pool are positioned on the same axis;
The circumferential limiting component is abutted against the lens barrel to prevent the radial runout and circumferential rotation of the lens barrel;
And the axial adjusting assembly is abutted against the lens barrel to adjust the axial position of the lens barrel.
Preferably, the circumference limiting component comprises a pressing block, a pressing jackscrew, a first steel ball, a guide block and a disc spring group, wherein the pressing block is fixed on the lens cone base and is positioned above the lens cone, the pressing block is provided with a screw hole penetrating through the lens cone, the screw hole of the pressing block is internally provided with the first steel ball, the guide block and the disc spring group from bottom to top in sequence, the lower end of the pressing jackscrew is screwed into the screw hole of the pressing block from the upper part of the pressing block and is abutted to the disc spring group, and the outer surface of the upper part of the lens cone is provided with a first groove extending in the axial direction, and the first steel ball extends out of the screw hole of the pressing block and is abutted to the first groove of the lens cone.
Preferably, the first groove of the lens barrel is a V-shaped groove, a U-shaped groove or a semicircular groove.
Preferably, the circumferential limiting assembly further comprises a lock nut, and the lock nut is installed at the upper end of the compression jackscrew to lock the compression jackscrew.
Preferably, the upper surface of the lens barrel base is provided with a second groove extending axially, the lower part of the lens barrel is arranged in the second groove, and the second groove is a V-shaped groove, a U-shaped groove or a semicircular groove.
Preferably, the axial adjusting assembly comprises an adjusting rod, a thread pair, a fixed block and a second steel ball, wherein the fixed block is fixed on the lens barrel base, the thread pair is fixed on the fixed block, the adjusting rod axially penetrates through a screw hole of the thread pair, and the second steel ball is positioned between the adjusting rod and the lens barrel and respectively abuts against the rear end of the adjusting rod and the front end face of the lens barrel.
Preferably, the device further comprises a rebound assembly, the rebound assembly comprises a compression spring and a spring baffle, the rear end face of the lens barrel is provided with an axially extending accommodating hole, the spring baffle is fixed on the lens barrel base, the front end of the compression spring is accommodated in the accommodating hole, and the rear end of the compression spring extends out of the accommodating hole and abuts against the spring baffle.
Preferably, the flow cell base is integrally formed with the barrel base.
Preferably, the lens assembly further comprises a gland, the lens barrel is provided with an axially extending through hole, a limiting boss is arranged in the through hole of the lens barrel, and the gland compresses the lens on the limiting boss of the lens barrel.
A flow cytometer comprising a lens adjustment mechanism of the flow cytometer described above.
Compared with the prior art, the invention has the beneficial effects that at least the following steps are included:
According to the lens adjusting mechanism, the center of the lens and the center line of the flow type pool are positioned on the same axis, the axial position of the lens barrel can be adjusted by arranging the axial adjusting component, the axial positions of the lens and the laser beam focus can be adjusted, radial runout and circumferential rotation of the lens barrel can be eliminated and prevented by arranging the circumferential limiting component, the positioning accuracy of the flow type pool and the focusing lens is ensured, the stability of the lens adjusting mechanism is improved, the processing cost of the lens adjusting mechanism is low, the adjusting performance is reliable, and the precision is high.
Drawings
FIG. 1 is a perspective view of a lens adjustment mechanism of a flow cytometer in accordance with an embodiment of the present invention.
FIG. 2 is a left side view of a lens adjustment mechanism of a flow cytometer in accordance with an embodiment of the present invention.
Fig. 3 is a schematic cross-sectional view of the lens adjustment mechanism of fig. 2 along line AA.
Fig. 4 is a front view of a lens adjustment mechanism of a flow cytometer in accordance with an embodiment of the present invention.
Fig. 5 is a schematic cross-sectional view of the lens adjustment mechanism of fig. 4 along line BB.
In the figure: 1. a lens adjustment mechanism; 10. a lens barrel base; 11. a second groove; 20. stream Chi De; 30. a lens assembly; 31. a lens barrel; 311. a through hole; 312. a limit boss; 313. a first groove; 32. a lens; 33. a gland; 40. a circumferential limit assembly; 41. briquetting; 42. compressing the jackscrews; 43. a first steel ball; 44. a guide block; 45. a disc spring set; 46. a connecting column; 47. a lock nut; 50. an axial adjustment assembly; 51. an adjusting rod; 52. a thread pair; 53. a fixed block; 54. a second steel ball; 60. a rebound assembly; 61. a compression spring; 62. spring baffle.
Detailed Description
Example embodiments will now be described more fully with reference to the accompanying drawings. However, the exemplary embodiments can be embodied in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus a repetitive description thereof will be omitted.
The words expressing the positions and directions described in the present invention are described by taking the drawings as an example, but can be changed according to the needs, and all the changes are included in the protection scope of the present invention.
Referring to fig. 1 to 5, the present invention provides a flow cytometer and a lens adjustment mechanism 1 of the flow cytometer, the lens adjustment mechanism 1 includes a lens barrel base 10, a flow cell base 20, a lens assembly 30, a circumferential limit assembly 40, and an axial adjustment assembly 50.
The lens barrel base 10 is used for installing the lens assembly 30, the flow type pool base 20 is used for installing the flow type pool (not shown), the existing lens barrel base 10 and the flow type pool base 20 are two separated parts, machining errors and assembly errors are easy to introduce during machining and installation of the structure, assembly accumulated errors are large, the flow type pool and the focusing lens are difficult to ensure in theoretical positions, the center of the flow type pool and the center of the focusing lens are difficult to ensure to be on the same axis, and researches show that the integral forming of the flow type pool base 20 and the lens barrel base 10 can avoid the installation errors, effectively overcome the defects, ensure that the center line of the flow type pool and the center of the focusing lens are on the same axis, and meanwhile, the installation and the debugging are simple and the efficiency is high.
The lens assembly 30 includes a lens barrel 31 and a lens 32, and may further include a pressing cover 33, wherein the lens barrel 31 is positioned on the barrel base 10, the lens 32 is mounted on the lens barrel 31, and the lens 32 may be a focusing lens. By machining, after the lens barrel 31 is mounted on the lens barrel base 10 and the flow cell is mounted on the flow cell base 20, the center of the lens 32 and the center of the flow cell are located on the same axis, and the center of the flow cell is the path of the flow of cells or particles in the flow cell, so that the light beam passing through the lens 32 is focused on the sample flow path of the flow cell.
Specifically, referring to fig. 3 and 5, the lens barrel 31 has an axially extending through hole 311, the through hole 311 is used for accommodating the lens 32 and passing the light source, a limiting boss 312 is arranged in the through hole 311 of the lens barrel 31, the lens 32 abuts against the limiting boss 312 after being placed in the through hole 311, and the pressing cover 33 presses the lens 32 against the limiting boss 312 of the lens barrel 31, so that the lens 32 is fixed.
In the combined regulator disclosed by CN205665453U and CN205665592U, the base of the lens barrel is arranged on a linear guide rail, the straightness of the axial position of the lens barrel is guaranteed through the linear guide rail, the following defects are found in practice, the linear guide rail has a gap, errors are also introduced during the installation of the linear guide rail, and an adjusting mechanism is unstable. The solution proposed by the present application for the above-mentioned problem is that a second groove 11 extending axially is provided on the upper surface of the lens barrel base 10, the lower portion of the lens barrel 31 is placed in the second groove 11, the second groove 11 is a V-shaped groove or a U-shaped groove, in other words, the cross section of the second groove 11 along the direction perpendicular to the extending direction is V-shaped or U-shaped, the second groove 11 is preferably a V-shaped groove, by pressing the lens barrel 31 into the V-shaped groove, the clearance and error which may be generated by the lens barrel base 10 in the prior art are eliminated, the stability of the lens adjusting mechanism 1 is improved, and the axial position of the lens barrel 31 can be adjusted and the straightness can be ensured.
Referring to fig. 1,3 and 5, the circumferential limit assembly 40 abuts against the lens barrel 31 to prevent radial runout and circumferential rotation of the lens barrel 31, and the circumferential limit assembly 40 includes a pressing block 41, a pressing jackscrew 42, a first steel ball 43, a guide block 44 and a disc spring group 45.
Wherein, the pressing block 41 is fixed on the lens barrel base 10 and is located above the lens barrel 31, in this embodiment, the pressing block 41 is fixed on the lens barrel base 10 through a connecting column 46 on the side, the connecting column 46 is fixed on the lens barrel base 10 through a screw, the pressing block 41 is provided with a screw hole penetrating up and down, a first steel ball 43, a guide block 44 and a disc spring group 45 are sequentially placed in the screw hole of the pressing block 41 from bottom to top, the disc spring group 45 can be composed of one or more disc springs, the lower end of the pressing jackscrew 42 is screwed into the screw hole of the pressing block 41 from above the pressing block 41 and is abutted against the disc spring group 45, the outer surface above the lens barrel 31 is provided with a first groove 313 extending axially, and the first steel ball 43 extends out of the screw hole of the pressing block 41 and is abutted against the first groove 313 of the lens barrel 31. The compressing jackscrew 42 provides proper compressing force through the disc spring group 45, the guide block 44 and the first steel ball 43, the compressing jackscrew 42 is matched with the disc spring group 45, the guide block 44 and the first steel ball 43 to enable the first steel ball 43 to be pressed into the first groove 313 of the lens cone 31, rebound compressing force is provided for the lens cone 31, compressing force of the compressing jackscrew 42 to the lens cone 31 can be adjusted by adjusting screwing quantity of the compressing jackscrew 42, the lens cone 31 is guaranteed not to jump radially and rotate circumferentially, limiting effect is achieved on the lens cone 31, coaxiality of a center line of a flow type pool and the center of the lens 32 is guaranteed, and finally stability and centering of an optical path are guaranteed.
The first groove 313 of the lens barrel 31 may be a V-groove, a U-groove or a semicircular groove, in other words, the cross section of the first groove 313 along the direction perpendicular to the extending direction is V-shaped, U-shaped or semicircular, when the axial position of the lens barrel 31 needs to be adjusted, the pressing jackscrew 42 is reversely screwed out, the first steel ball 43 is loosened, and the first groove 313 of the lens barrel 31 moves axially under the guiding action of the first steel ball 43; after the adjustment is finished, the first steel ball 43 is tightly pressed in the first groove 313 by screwing the pressing jackscrew 42, the lens barrel 31 cannot generate circumferential rotation, radial runout and circumferential rotation of the lens barrel 31 are effectively prevented, and the stability and the centering of an optical path are ensured. Referring to fig. 1,3 and 5, the circumferential limit assembly 40 further includes a lock nut 47, the lock nut 47 may be a thin nut, the lock nut 47 is installed at an upper end of the compression jackscrew 42, and after the position adjustment of the lens barrel 31 is completed, the compression jackscrew 42 may be locked by the lock nut 47 at the upper end of the compression jackscrew 42, thereby preventing the compression jackscrew 42 from loosening and ensuring the stability of the structure.
Referring to fig. 1 and 3, the axial adjustment assembly 50 includes an adjustment rod 51, a screw pair 52, a fixed block 53, and a second steel ball 54. Wherein, the fixed block 53 is fixed on the lens barrel base 10, the screw pair 52 is fixed on the fixed block 53, in this embodiment, the screw pair 52 is fixed on one side of the fixed block 53 facing away from the lens barrel 31, the adjusting rod 51 axially passes through the screw hole of the screw pair 52, the second steel ball 54 is located between the adjusting rod 51 and the lens barrel 31 and respectively abuts against the rear end of the adjusting rod 51 and the front end face of the lens barrel 31, the adjusting rod 51 is screwed in and then transmits the acting force to the lens barrel 31 through the second steel ball 54, so as to promote the lens barrel 31 to move, thereby adjusting the axial position of the lens barrel 31. Optionally, the rear end of the adjusting rod 51 is an inward concave conical surface, and the rear end conical surface of the adjusting rod 51 and the second steel ball 54 are coated with grease, so that the second steel ball 54 can be attached to the rear end conical surface of the adjusting rod 51.
Referring to fig. 3, the lens adjusting mechanism 1 of the flow cytometer further includes a rebound assembly 60, the rebound assembly 60 includes a compression spring 61 and a spring baffle 62, an axially extending accommodating hole is provided on a rear end surface of the lens barrel 31, the spring baffle 62 is fixed on the lens barrel base 10, a front end of the compression spring 61 is accommodated in the accommodating hole, a rear end of the compression spring 61 extends out of the accommodating hole and abuts against the spring baffle 62, after the rebound assembly 60 is adopted, after the adjusting rod 51 is screwed into the screw pair 52 to cause the lens barrel 31 to move toward the spring baffle 62, the lens barrel 31 compresses the compression spring 61 and causes the compression spring 61 to accumulate elastic force; when the adjusting lever 51 is reversely rotated out, the compression spring 61 releases the elastic force and urges the lens barrel 31 to move in a direction opposite to the spring shutter 62, so that the use of the rebound assembly 60 can ensure smoothness and reliability in reverse adjustment of the lens barrel 31.
In summary, the center of the lens and the center line of the flow type pool are positioned on the same axis, the axial position of the lens barrel can be adjusted by arranging the axial adjusting component, the axial positions of the lens and the laser beam focus can be adjusted, the radial runout and the circumferential rotation of the lens barrel can be eliminated and prevented by arranging the circumferential limiting component, the positioning accuracy of the flow type pool and the focusing lens is ensured, the stability of the lens adjusting mechanism is improved, the processing cost of the lens adjusting mechanism is low, the adjusting performance is reliable, and the precision is high.
While embodiments of the present invention have been shown and described, it will be understood that the above embodiments are illustrative and not to be construed as limiting the invention, and that changes, modifications, substitutions and alterations may be made therein by those of ordinary skill in the art without departing from the spirit and scope of the invention, all such changes being within the scope of the appended claims.
Claims (7)
1. A lens adjustment mechanism for a flow cytometer, comprising:
A lens barrel base and a flow Chi De for mounting a flow cell;
The lens assembly comprises a lens barrel positioned on a lens barrel base and a lens arranged on the lens barrel, wherein the lens barrel is arranged on the lens barrel base, and after a flow type pool is arranged on the flow type pool base, the center of the lens and the center line of the flow type pool are positioned on the same axis;
The circumferential limiting component is abutted against the lens barrel to prevent the radial runout and circumferential rotation of the lens barrel;
an axial adjustment assembly abutting the barrel to adjust an axial position of the barrel;
the circumferential limiting assembly comprises a pressing block, a pressing jackscrew, a first steel ball, a guide block and a disc spring group, wherein the pressing block is fixed on a lens barrel base and is positioned above the lens barrel, the pressing block is provided with a screw hole penetrating through the top and bottom, the first steel ball, the guide block and the disc spring group are sequentially arranged in the screw hole of the pressing block from bottom to top, the lower end of the pressing jackscrew is screwed into the screw hole of the pressing block from above the pressing block and is abutted against the disc spring group, the outer surface above the lens barrel is provided with a first groove extending axially, and the first steel ball extends out of the screw hole of the pressing block and is abutted against the first groove of the lens barrel;
The axial adjusting assembly comprises an adjusting rod, a thread pair, a fixed block and a second steel ball, the fixed block is fixed on the lens barrel base, the thread pair is fixed on the fixed block, the adjusting rod axially penetrates through a screw hole of the thread pair, and the second steel ball is positioned between the adjusting rod and the lens barrel and respectively abuts against the rear end of the adjusting rod and the front end face of the lens barrel;
The device comprises a lens barrel, and is characterized by further comprising a rebound assembly, wherein the rebound assembly comprises a compression spring and a spring baffle, an accommodating hole extending axially is formed in the rear end face of the lens barrel, the spring baffle is fixed on the lens barrel base, the front end of the compression spring is accommodated in the accommodating hole, and the rear end of the compression spring extends out of the accommodating hole and abuts against the spring baffle.
2. The lens adjustment mechanism of claim 1, wherein the first groove of the barrel is a V-groove, a U-groove, or a semi-circular groove.
3. The lens adjustment mechanism of claim 1, wherein the circumferential limit assembly further comprises a lock nut mounted on an upper end of the compression jackscrew to lock the compression jackscrew.
4. The lens adjusting mechanism of the flow cytometer of claim 1 wherein the upper surface of the barrel base has a second axially extending groove, the lower portion of the barrel is disposed in the second groove, and the second groove is a V-groove, a U-groove, or a semi-circular groove.
5. The flow cytometer lens adjustment mechanism of claim 1 wherein the flow cell base is integrally formed with the barrel base.
6. The lens adjustment mechanism of claim 1, wherein the lens assembly further comprises a gland, the barrel having an axially extending through bore, the barrel having a limit boss therein, the gland compressing the lens against the limit boss of the barrel.
7. A flow cytometer comprising a lens adjustment mechanism of the flow cytometer of any of claims 1 to 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811604089.7A CN109490178B (en) | 2018-12-26 | 2018-12-26 | Flow cytometer and lens adjusting mechanism thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811604089.7A CN109490178B (en) | 2018-12-26 | 2018-12-26 | Flow cytometer and lens adjusting mechanism thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109490178A CN109490178A (en) | 2019-03-19 |
| CN109490178B true CN109490178B (en) | 2024-05-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811604089.7A Active CN109490178B (en) | 2018-12-26 | 2018-12-26 | Flow cytometer and lens adjusting mechanism thereof |
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| Country | Link |
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| CN (1) | CN109490178B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114137724A (en) * | 2022-01-19 | 2022-03-04 | 北京层浪生物科技有限公司 | Optical system for particle analyzer |
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|---|---|---|---|---|
| JPS6061710A (en) * | 1983-09-16 | 1985-04-09 | Ricoh Co Ltd | Installing position adjusting device of image forming element |
| CN201322720Y (en) * | 2008-12-12 | 2009-10-07 | 深圳迈瑞生物医疗电子股份有限公司 | Optical adjusting bracket |
| CN103307553A (en) * | 2013-06-21 | 2013-09-18 | 嘉善加斯戴克医疗器械有限公司 | Device for accurately adjusting one-dimensional position with hand wheel |
| WO2014138038A1 (en) * | 2013-03-05 | 2014-09-12 | Exelis Inc. | Translational optic alignment locking device |
| CN204575500U (en) * | 2015-04-23 | 2015-08-19 | 广州埃克森生物科技有限公司 | Differential hematology analyzer optical system governor motion |
| CN205665453U (en) * | 2016-06-06 | 2016-10-26 | 常州必达科生物科技有限公司 | Combination regulator of flow chamber and focusing mirror |
| CN209280529U (en) * | 2018-12-26 | 2019-08-20 | 常州必达科生物科技有限公司 | A kind of flow cytometer and its lens adjusting mechanism |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107250762B (en) * | 2015-03-06 | 2020-06-30 | 贝克顿·迪金森公司 | Light collection system and methods of making and using same |
-
2018
- 2018-12-26 CN CN201811604089.7A patent/CN109490178B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6061710A (en) * | 1983-09-16 | 1985-04-09 | Ricoh Co Ltd | Installing position adjusting device of image forming element |
| CN201322720Y (en) * | 2008-12-12 | 2009-10-07 | 深圳迈瑞生物医疗电子股份有限公司 | Optical adjusting bracket |
| WO2014138038A1 (en) * | 2013-03-05 | 2014-09-12 | Exelis Inc. | Translational optic alignment locking device |
| CN103307553A (en) * | 2013-06-21 | 2013-09-18 | 嘉善加斯戴克医疗器械有限公司 | Device for accurately adjusting one-dimensional position with hand wheel |
| CN204575500U (en) * | 2015-04-23 | 2015-08-19 | 广州埃克森生物科技有限公司 | Differential hematology analyzer optical system governor motion |
| CN205665453U (en) * | 2016-06-06 | 2016-10-26 | 常州必达科生物科技有限公司 | Combination regulator of flow chamber and focusing mirror |
| CN209280529U (en) * | 2018-12-26 | 2019-08-20 | 常州必达科生物科技有限公司 | A kind of flow cytometer and its lens adjusting mechanism |
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| Publication number | Publication date |
|---|---|
| CN109490178A (en) | 2019-03-19 |
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