CN109481609A - It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer - Google Patents

It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer Download PDF

Info

Publication number
CN109481609A
CN109481609A CN201811651609.XA CN201811651609A CN109481609A CN 109481609 A CN109481609 A CN 109481609A CN 201811651609 A CN201811651609 A CN 201811651609A CN 109481609 A CN109481609 A CN 109481609A
Authority
CN
China
Prior art keywords
radix
chinese medicine
adlay
pheretima
trigone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811651609.XA
Other languages
Chinese (zh)
Inventor
王红英
侯立玲
肖丽丽
李媛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201811651609.XA priority Critical patent/CN109481609A/en
Publication of CN109481609A publication Critical patent/CN109481609A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/84Valerianaceae (Valerian family), e.g. valerian
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to tcm fields, disclose a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer.Chinese medicine composition includes radix scutellariae 15-21g, adlay 9-12g, cordate houttuynia 9-15g, field pennycress 9-15g, trigone 6-9g, curcuma zedoary 6-9g, bombyx batryticatus 6-9g, pheretima 6-9g, tuber of pinellia 9-15g, dried orange peel 9-15g, Radix Paeoniae Alba 9-15g, Radix Angelicae Sinensis 9-15g, Prunella vulgaris 9-15g, oldenlandia diffusa 15-30g, Radix Glycyrrhizae 6-15g.Preparation method is to be put into casserole above-mentioned Chinese medicine, adds water 1000ml, impregnates 20 minutes, needs to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to small fire after enduring out and is slowly endured, small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures out, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each primary.The effect of clearing lung and eliminating phlegm is played in the mutual compatibility of each drug of the present invention, mutually auxiliary help altogether, activating microcirculation and removing stasis medicinal.

Description

It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer
Technical field
The invention belongs to technical field of Chinese medicine, specifically, being related to a kind of for treating syndrome of intermin-gled phlegm and blood stasis lung cancer Chinese medicine composition and preparation method.
Background technique
Lung cancer is one of most common malignant tumour all over the world, and disease incidence is still being increased in majority state, in China, lung Cancer accounts for the first place of common cancer in city, and rural area accounts for the 3rd, and disease incidence is increased significantly, and needs to cause widely weight Depending on.Patients with lung cancer complicated clinical manifestation, using cough, hemoptysis or blood-stained sputum, uncomfortable in chest, pectoralgia as main clinical manifestation.
Though ancient medicine is without pulmonary carcinosis name, early on the books to its symptom and sign.In detail such as " Plain Questions jade machine, which is really hidden, discusses a piece " Carefully describe advanced lung cancer fever, pectoralgia draws shoulder back, cachectic symptom, it is indicated that " serious disease is withered, obvious emaciation and muscular atrophy, and gas is full in the heart, Wheeze inconvenience, interior pain draws shoulder item, and it is broken that body heat takes off meat ", Difficult Classic claims that " product of lung, it is beautifully adorned that name says breath, under right rib, covers as large as bosom, long Endlessly, make us spilling wash rice fever and chills, breath with cough, hair lung is stopped up ".The scopes such as " cough " of lung cancer category Chinese medicine, " hemoptysis ", " pectoralgia ".
" phlegm " and " stasis of blood " is two class different pathological factors in Chinese medicine traditional theory, but closely related, reciprocal causation, often Often and folder is complex as disease, becomes a kind of pathological factor of new speciality, and pathological characters are phlegm and blood stasis, and the one of clinical manifestation Range of conditions is referred to as syndrome of intermin-gled phlegm and blood stasis.Though the title for proposing " phlegm and blood stasis " is not known in ancient literature, related phlegm and blood stasis being derived from the same source, It is long-standing with disease, the same theory and practice controlled.Modern study confirms:
" phlegm card " and " stasis syndrome " has common biochemical foundation.It is seriously ill by some difficulties are controlled from " phlegm and blood stasis " to face card Disease, often obtains effective, is the ring being of great significance in pathogenesis theory.Homogeny of clear fluid and blood is popular such as essence of water and grain institute metaplasia It is blood in person in arteries and veins, the micro- epigenesist in passages through which vital energy circulates of cloth is liquid, relies the gasification of internal organs, and inside and outside vascular, money is raw each other turns Change, illustrates that blood is raw with body fluid, saliva is deposited with blood.Therefore under pathological state, solidifying saliva is then phlegm, and then at the stasis of blood, phlegm gathers then blood knot for stasis, Then phlegm is raw for blood clotting so that reciprocal causation, with disease, heterozygosis is to suffer from, with and be phlegm-blood stasis with disease, provide theoretical foundation.
For the treatment of the symptoms such as patients with lung cancer cough and expectoration, chest distress, pectoralgia, clinical treatment is with radiotherapy, chemotherapy, target Based on treatment, in addition, having the drugs such as anti-inflammatory, analgesic still to improve patient's above-mentioned symptom.Anti-inflammatory drug there are digestive tract damage, The adverse reactions such as liver and kidney dysfunction, allergy, Cardiovascular Damage, there are constipation, nausea and vomiting, drowsiness and mistakes for analgesic drug product Spend the adverse reactions such as calmness, urinary hesitancy.Seriously affect life in patients.
In Chinese traditional treatment, lung cancer is divided into the strongly fragrant mutual knot card of phlegm, syndrome of deficiency of both qi and yin, spleen deficiency phlegm according to its different clinical manifestation Wet card, deficiency of Yin phlegm heat symptom-complex.Its syndrome of intermin-gled phlegm and blood stasis clinical manifestation: unsmooth, blood-stained sputum of coughing, chest and hypochondrium or uncomfortable in chest out of breath, purple lips, Dry, constipation, tongue is dark red, there is ecchymosis, whitish tongue or Huang, wiry and rolling pulse.Treatment is mostly using clearing lung and eliminating phlegm, activating microcirculation and removing stasis medicinal as principle of reatment.
Summary of the invention
It is above-mentioned it is a primary object of the present invention to overcome the shortcomings of, it provides a kind of for treating in syndrome of intermin-gled phlegm and blood stasis lung cancer Drug composition and preparation method thereof can be obviously improved the clinical symptoms such as patients with lung cancer cough and expectoration, chest distress, pectoralgia, subtract Few abuse of antibiotics and analgesic drug product application bring adverse reaction.
To achieve the above object, the present invention provides a kind of for treating the Chinese traditional medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer Object, including radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, summer are withered Grass, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned each raw material is respectively radix scutellariae 15-21g, adlay 9-12g, cordate houttuynia according to poidometer It is 9-15g, field pennycress 9-15g, trigone 6-9g, curcuma zedoary 6-9g, bombyx batryticatus 6-9g, pheretima 6-9g, tuber of pinellia 9-15g, dried orange peel 9-15g, white Chinese herbaceous peony 9-15g, Radix Angelicae Sinensis 9-15g, Prunella vulgaris 9-15g, oldenlandia diffusa 15-30g, Radix Glycyrrhizae 6-15g.
It is a kind of for treating the optimal technical scheme of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including Huang as the present invention A kind of reed mentioned in ancient books, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia Grass and Radix Glycyrrhizae etc., above-mentioned each raw material is respectively radix scutellariae 16-20g, adlay 10-11g, cordate houttuynia 10-13g, Patrinia scaniosaefolia according to poidometer Careless 10-13g, trigone 7-8g, curcuma zedoary 7-8g, bombyx batryticatus 7-8g, pheretima 7-8g, tuber of pinellia 10-13g, dried orange peel 10-14g, Radix Paeoniae Alba 10- 14g, Radix Angelicae Sinensis 10-13g, Prunella vulgaris 10-13g, oldenlandia diffusa 18-27g, Radix Glycyrrhizae 8-12g.
It is a kind of for treating the optimal technical scheme of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including Huang as the present invention A kind of reed mentioned in ancient books, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia Grass and Radix Glycyrrhizae etc., above-mentioned each raw material is respectively radix scutellariae 18g, adlay 11g, cordate houttuynia 12g, field pennycress 12g, three according to poidometer Rib 8g, curcuma zedoary 8g, bombyx batryticatus 8g, pheretima 8g, tuber of pinellia 12g, dried orange peel 11g, Radix Paeoniae Alba 12g, Radix Angelicae Sinensis 11g, Prunella vulgaris 11g, oldenlandia Careless 23g, Radix Glycyrrhizae 10g.
It is a kind of for treating the optimal technical scheme of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including Huang as the present invention A kind of reed mentioned in ancient books, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia Grass and Radix Glycyrrhizae etc., above-mentioned each raw material is respectively as follows: radix scutellariae 15g, adlay 9g, cordate houttuynia 15g, field pennycress 15g, trigone according to poidometer 9g, curcuma zedoary 9g, bombyx batryticatus 9g, pheretima 6g, tuber of pinellia 9g, dried orange peel 9g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 9g, Prunella vulgaris 15g, oldenlandia diffusa 30g, Radix Glycyrrhizae 8g.
Further, the present invention also provides a kind of for treating the preparation side of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer Method includes the following steps, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine are put into casserole, add water 1000ml, need to cover Medicine impregnates 20 minutes, needs to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, after enduring out Switch to small fire slowly to endure, small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, is continued big Fire is endured out, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, sooner or later temperature It takes each primary.
Compared with prior art, the present invention has the beneficial effects that
The effect of clearing lung and eliminating phlegm is played in the mutual compatibility of each drug of the present invention, mutually auxiliary help altogether, activating microcirculation and removing stasis medicinal.It gets rid of evils and does not hurt just, And pay attention to caring for shield taste, mitigation anti-inflammatory drug, relieve the pain drug bring side effect of digestive tract and the side reactions such as constipation, drowsiness.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all It belongs to the scope of protection of the present invention.
A specific embodiment of the invention is described in further detail and is illustrated below:
Embodiment 1
It is provided by the invention a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including radix scutellariae, adlay, fish raw meat Grass, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., Each raw material is respectively radix scutellariae 15g, adlay 9g, cordate houttuynia 15g, field pennycress 15g, trigone 9g, curcuma zedoary 9g, bombyx batryticatus according to poidometer 9g, pheretima 6g, tuber of pinellia 9g, dried orange peel 9g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 9g, Prunella vulgaris 15g, oldenlandia diffusa 30g, Radix Glycyrrhizae 15g.
The present invention also provides a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including with Lower step, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, when Return, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine is put into casserole, and adds water 1000ml, needs to cover Chinese medicine, is impregnated 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to after enduring out small Fire is slowly endured, and small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures Open, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each Once.
Embodiment 2
It is provided by the invention a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including radix scutellariae, adlay, fish raw meat Grass, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., Each raw material is respectively radix scutellariae 18g, adlay 11g, cordate houttuynia 12g, field pennycress 12g, trigone 8g, curcuma zedoary 8g, bombyx batryticatus according to poidometer 8g, pheretima 8g, tuber of pinellia 12g, dried orange peel 11g, Radix Paeoniae Alba 12g, Radix Angelicae Sinensis 11g, Prunella vulgaris 11g, oldenlandia diffusa 23g, Radix Glycyrrhizae 10g.
The present invention also provides a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including with Lower step, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, when Return, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine is put into casserole, and adds water 1000ml, needs to cover Chinese medicine, is impregnated 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to after enduring out small Fire is slowly endured, and small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures Open, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each Once.
Embodiment 3
It is provided by the invention a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including radix scutellariae, adlay, fish raw meat Grass, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., Each raw material is respectively radix scutellariae 20g, adlay 11g, cordate houttuynia 13g, field pennycress 13g, trigone 8g, curcuma zedoary 8g, bombyx batryticatus according to poidometer 8g, pheretima 8g, tuber of pinellia 13g, dried orange peel 14g, Radix Paeoniae Alba 14g, Radix Angelicae Sinensis 13g, Prunella vulgaris 13g, oldenlandia diffusa 27g, Radix Glycyrrhizae 12g.
The present invention also provides a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including with Lower step, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, when Return, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine is put into casserole, and adds water 1000ml, needs to cover Chinese medicine, is impregnated 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to after enduring out small Fire is slowly endured, and small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures Open, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each Once.
Embodiment 4
It is provided by the invention a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including radix scutellariae, adlay, fish raw meat Grass, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., Each raw material is respectively radix scutellariae 21g, adlay 12g, cordate houttuynia 9g, field pennycress 9g, trigone 6g, curcuma zedoary 6g, bombyx batryticatus according to poidometer 6g, pheretima 9g, tuber of pinellia 15g, dried orange peel 15g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 15g, Prunella vulgaris 9g, oldenlandia diffusa 15g, Radix Glycyrrhizae 6g.
The present invention also provides a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including with Lower step, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, when Return, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine is put into casserole, and adds water 1000ml, needs to cover Chinese medicine, is impregnated 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to after enduring out small Fire is slowly endured, and small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures Open, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each Once.
Embodiment 5
It is provided by the invention a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including radix scutellariae, adlay, fish raw meat Grass, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., Each raw material is respectively radix scutellariae 16g, adlay 10g, cordate houttuynia 10g, field pennycress 10g, trigone 7g, curcuma zedoary 7g, bombyx batryticatus according to poidometer 7g, pheretima 7g, tuber of pinellia 10g, dried orange peel 10g, Radix Paeoniae Alba 10g, Radix Angelicae Sinensis 10g, Prunella vulgaris 10g, oldenlandia diffusa 18g, Radix Glycyrrhizae 8g.
The present invention also provides a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, including with Lower step, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, when Return, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine is put into casserole, and adds water 1000ml, needs to cover Chinese medicine, is impregnated 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, and is switched to after enduring out small Fire is slowly endured, and small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water enter the dregs of a decoction, continues high fire and endures Open, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two equal portions, is warmly taken sooner or later each Once.
The Chinese medicine composition for being used to treat syndrome of intermin-gled phlegm and blood stasis lung cancer in the present invention, also known as clearing lung-heatization product side.
Wherein, the radix scutellariae in above-mentioned clearing lung-heatization product side, adlay are monarch drug in a prescription, and removing summer-heat lung heat is relieving cough and reducing sputum;Cordate houttuynia, Patrinia scaniosaefolia Careless clearing lung and eliminating phlegm;Trigone, curcuma zedoary, bombyx batryticatus, pheretima dissipating blood stasis with potent drugs;Radix Angelicae Sinensis, Radix Paeoniae Alba nourshing blood and promoting blood circulation;The tuber of pinellia, dried orange peel clearing damp resolving sputum;Summer The clearing heat and detoxicating dissipating bind of withered grass, oldenlandia diffusa is swollen;Radix Glycyrrhizae tune medicine is in.Clinically, it can be carried out facing card plus-minus according to patient's state of an illness.
The nature and flavor of each raw material, channel tropism and effect and effect in the above various embodiments disclosed by the invention are as follows:
Radix scutellariae: it is bitter, cold in nature, can heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention have heat-clearing and damp-drying drug, cool blood miscarriage prevention, removing toxic substances Effect.Shennong's Herbal: main all hot jaundice, intestines Bleach let out benefit, relieve oedema or abdominal distension through diuresis or purgation, and lower blood closes, (controlling) malignant sore, subcutaneous ulcer erosion, fiery ulcer." Bie Lu ": phlegm is treated Heat, pathogenic heat in the stomach, small eilema, disappear paddy, and sharp small intestine, woman's blood closes, and lower blood, abdominal pain in children are revealed in leaching.Clinic still have antibacterial, decompression, Platelet aggregation-against, anticancer and other effects.The clinical application good anti-bacterial effect of radix scutellariae, and do not develop drug resistance.
Adlay: property slightly sweet flavor is slightly cold, has inducing diuresis for removing edema, invigorating spleen to remove dampness, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus and other effects, is common Damp-clearing drug." book on Chinese herbal medicine is newly organized ": the most kind Li Shui of adlay, the gas that unlikely loss is Kidney-Yin, all wetness hyperactivity are most preferably used in lower part of the body person It, depending on the weight of disease, the number of mutatis mutandis medicine, then yin-yang is not hurt, and diseases caused by dampness is easily gone.Therefore all diseases for meeting water-wet, with one, two liang of adlay For monarch, and the taste of the invigorating spleen to remove dampness of assistant, do not have it is not fast in the person of proving effective, if its thin smell gentle and gently with it, it is unhelpful.The heart of a lotus seed Rice has antitumor, raising immunity, hypoglycemic, blood pressure lowering, beauty face-whitening-nourishing and other effects.
Cordate houttuynia: acrid flavour, it is cold, it is distributed in lung channel.It can clearing heat and detoxicating, detumescence treatment sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach invigorating It helps digestion, is pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from real heat, heat toxin, damp evil, disease heat is controlled." herbal guiding principle Mesh ": radiate malicious carbuncle swells, sore hemorrhoid rectal prolapse, shop disease of breaking, solution Nao poison." the southern regions of the Yunnan Province book on Chinese herbal medicine ": controlling pulmonary abscess cough band purulence blood, phlegm have it is stench, greatly Intestines heat toxin treats hemorrhoid.Modern pharmacology experiment shows that this product has the effects that antibacterial, antiviral, raising immunity of organisms, diuresis.
Field pennycress: cool in nature, acrid flavour, hardship.It can clearing heat and detoxicating, removing blood stasis and expelling pus.Modern pharmacological research, field pennycress are anti-with having The effects of pathogenic microorganism, calmness, anticancer, Hepatoprotective cholagogue.
Trigone: it is pungent, bitter, it puts down.For abdominal mass lump in the abdomen, dysmenorrhea, blood stasis closed, chest impediment and cardialgia, dyspepsia distending pain." herbal guiding principle Mesh ": logical Liver Channel hematocele, woman month water, postpartum extravesated blood." opening treasured ": old addiction abdominal mass, accumulation agglomeration, postpartum extravesated blood blood knot lead to the moon Water, induced abortion relieve pain sharp gas.
Curcuma zedoary: pungent, bitter, temperature.Return liver, the spleen channel.Energy breaking blood and promoting the circulation of qi, clearing stagnation and killing pain.For abdominal pain due to blood stasis, hepatosplenomegaly, the heart Abdominal distention and pain, accumulation, women's blood stasis, traumatic injury are had a pain eating accumulation.It still can promoting digestion and removing indigestion: being used for the stomach abdomen of eating accumulation Distending pain often matches melanoidin malt, charred SEMEN ARECAE." Thunder God processes pharmacological property solution ": " empty people prohibits it." " book on Chinese herbal medicine is just ": " property firmness is high, non-to have heavily fortified point Stupid product should not be used."
Bombyx batryticatus: it is acrid flavour, salty, it is mild-natured, have and expels endogenous wind to relieve convulsion, reducing phlegm and resolving masses, the effect of, clinic is chiefly used in controlling tangible packet Block, such as tubercle, pharynx swelling pain, scrofula, wind sore urticaris etc..It is all taken to lead to scattered energy." Bencao Jingshu ": all apoplexy lockjaws, children are frightened The epilepsy morbid night crying of babies caused by deficiency of blood channels and collaterals strength urgency, and is that patient avoids it without exopathogen since the state of mind of having a guilty conscience is not peaceful.Modern pharmacological research has Internal heat anticance, for carcinoma product poison: it is anticonvulsion, anti-inflammatory the effects of.
Pheretima: cold in nature, taste is salty.There is the effect of heat-clearing, calming the liver, Zhichuan, dredging collateral.Return liver, stomach, lung, bladder meridian." book on Chinese herbal medicine Through dredging " the manic person of typhoid fever Fei Yangming real heat should not use, and warm disease should not be used without high fever and taste element weak person, jaundice edge great Lao, abdominal distension Belong to spleen kidney deficiency, the deficiency of Yin is at labor illness person, at being avoided.Modern pharmacological research has antipyretic, calm, anticonvulsant action.Have slowly and Lasting antihypertensive effect.The significant diastole bronchus of energy, and play antiasthmatic effect.There is apparent inhibition thrombosis to act on.
The tuber of pinellia: eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, coma due to blocking of the respiratory system head Bitterly, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus;It is raw to use controlling outward carbuncle swells subcutaneous nodule.Shennong's Herbal: " main typhoid fever fever and chills, hardness in the epigastrium, lower gas, Laryngopharynx swelling and pain, dizzy chest is swollen, and cough is inverse, borborygmus, hidroschesis." modern pharmacological research, the tuber of pinellia still have antibechic, eliminating the phlegm, antitumor, anticoagulant The effects of.Clinically there is the tuber of pinellia to obtain good therapeutic effect to treatment cancer of the esophagus, gastric cancer, tongue cancer, cutaneum carcinoma and malignant lymphoma Report.
It is dried orange peel, bitter, pungent, it is warm-natured.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum. " Mingyi Bielu ": lower gas, preventing or arresting vomiting.Compendium of Material Medica: treat vomiting gastric disorder causing nausea it is noisy, when hydroptysis.Modern pharmacological research, dried orange peel have The effects of expansion bronchus, eliminating the phlegm, anti-inflammatory, prevention of arterial hardening, promotion digestion.
Radix Paeoniae Alba is bitter, sour, slightly cold.Calming the liver and relieving pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For headache and dizziness, hypochondriac pain, abdominal pain, four limbs Contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat.Shennong's Herbal: " bitter is put down." " Wu Pu Bencao ": " paulownia monarch: it is sweet, it is nontoxic.Qi Primary: salty.Li Shi: Slight Cold.Thunder God: acid." modern pharmacological research Radix Paeoniae Alba has antibacterial action.
Radix Angelicae Sinensis is sweet, pungent, temperature compensation blood;Promoting blood circulation;Menstruction regulating and pain relieving;Moisturizing dryness and lubricating intestine.The main all cards of the deficiency of blood;Irregular menstruation;Menostasis;Bitterly Through;Abdominal mass knot is poly-;Metrorrhagia and metrostaxis;Asthenia cold abdominalgia;Flaccidity syndrome and arthralgia syndrome;Numbness;Intestines are dry and shit is difficult;Weight after dysentery with bloody stool;Ulcer sores;Injury from falling down. " medicine to ": disliking wet face, fears ginger." Bencao Jingshu ": stomach is weak, and diarrhea is half congealed thin and all the spleen-stomach diseases dislike food, do not think to eat and eat Do not disappear, and disable it, i.e., must not also enter before postpartum tire.
Motherland's medicine thinks that Radix Angelicae Sinensis is sweet in flavor and weighs, therefore can specially enrich blood, and gas is light and pungent, thus again can promoting circulation of blood, bowl spares has, There is benefit in row, is the key medicine in blood.Thus, it can enrich blood and invigorate blood circulation, not only can promoting menstruation, but also can be active.
Prunella vulgaris: it is pungent, bitter, it trembles with fear.Return liver, gallbladder channel.Its effect: clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating.Shennong's Herbal: " main fever and chills, scrofula, mouse fistula, head sore break disease.Goitre knot gas is dissipated, foot swells arthritis with fixed pain caused by dampness.' modern clinic to treat high blood pressure, helps Decompression;It takes its mass dissipating and swelling eliminating and common control Thyroid Gland Swell, enlargement of lymph nodes, the proliferation of mammary gland, hypertension etc. and belong to the hot person of liver.
Oldenlandia diffusa: the major functions: dyspnea and cough due to lung-heat;Abscess of throat;Acute appendicitis;Furuncle sore;Venomous snake bite;Puckery pain of heat gonorrhea;Water It is swollen;Dysentery;Enteritis;Jaundice with damp-heat pathogen;It is good at a variety of cancerous swellings for the treatment of.Pharmacological action: 1, enhance immune function;2, tumor-inhibiting action.
Radix Glycyrrhizae is flat, sweet, is the Chinese medicine of tonifying Qi benefit spleen simply, and inside Chinese medicine, there are many effect of Radix Glycyrrhizae, mends except having Except gas, beneficial spleen, also has the function of clearing heat and detoxicating, diuresis promoting.Radix Glycyrrhizae energy emergency, moreover it is possible to play the work of the reconciliation to all medicines With.
Doctor trained in Western medicine therapeutic evaluation: according to Lung Cancer Symptoms scalar quantization table, wherein
Patient takes orally criterion of therapeutical effect behind clearing lung-heatization product side:
Above-mentioned symptom evaluates criterion of therapeutical effect after symptomatic treatment:
It is effective: rank scores alleviate earlier above 60% or more or patient after treating without above-mentioned symptom exist;
Effective: rank scores alleviate 30% or more earlier above;
Invalid: symptom is without alleviation or exacerbation of symptoms;
It is observed that 100 patients cough is obvious, after clearing lung-heatization product side is treated, 80 people are effective, and 10 people are effective, 10 people without Effect, effective percentage 90%;95 people of expectoration patient, 68 people are effective, and 12 people are effective, and 15 people are invalid, effective percentage 84.2%;Patients with hemoptysis 47 People, 21 people are effective, and 13 people are effective, and 13 people are invalid, effective percentage 72.3%;98 people of chest pain patients, effective 54 people, effective 26 people, nothing Imitate 18 people, effective percentage 81.6%.Total effective rate 82.0%.
Practical typical case:
Case 1: Ma, male, 66 years old, address was Dezhou City Shandong Province Yueling City, was engaged in agriculture, and IV phase of adenocarcinoma of lung, cranium brain turns Shifting, Bone tumour, adrenal gland transfer.Once in 2 radiotherapy of Yueling City the People's Hospital row, parallel anti-Bone tumour treatment, when showing patient still Have a cough and expectoration, cough spits the viscous phlegm of white, when there is night cough to wake up, influence to sleep, no hemoptysis, no pectoralgia cough after anti-inflammatory treatment Shape slightly improves, and by oral administration after clearing lung-heatization product Chinese medicine, patient's cough symptom is obviously improved after 5 days, occasionally there is cough daytime, and night sleeps Sleeping improves, follow-up after medication 1 month, patient experiences stable disease, and no cough aggravates.
Case 2: it is huge so-and-so, male, 67 years old, address was the Dezhou City Shandong Province Pingyuan County town Qian Cao, the retired, lung cancer, lung Interior transfer, pleural effusion, row local lesion RF ablation, and give gemcitabine+4 period of Nedaplatin chemotherapy.There is chest when existing patient Bitterly, non-oral pain alleviating drug, NRS4 point occasionally have cough and expectoration a daytime, night not cough, no chest distress, no hemoptysis.It advises oral clear Lungization product side, patient's pectoralgia remission after 1 week, NRS2 points, following the service top, follow-up after 1 month, patient experiences stable disease, NRS0 Point.
Case 3: Mr. Li, male, 59 years old, address was the town Yucheng majoy Xin Dian, and resident, lung cancer, mediastinal lymph carries down It moves.Non- row other treatment.When have a cough and expectoration, cough spits the viscous phlegm of white, and occasionally there is cough at night, spits blood, 5 mouthfuls or so of day, blood/phlegm: 1/2.Oral Yunnan Baiyao Capsule, and give we and take orally, it is evaluated after 1 week, patient is alleviated without hemoptysis, cough symptom, still there is daytime Cough, expectoration are easily spat, and advise deactivated Yunnan Baiyao, the following the service party, patient is alleviated, occasionally had dry without hemoptysis, cough symptom after 1 month Cough.
Case 4: Mr. Wang, male, 65 years old, address was Shandong Province, city, Qihe County, resident, adenocarcinoma of lung, intrapulmonary transfer thoracic cavity Hydrops.Oral Gefitinib drug is so far.Have a cough and expectoration now, cough spits the viscous phlegm of white, and occasionally there is a cough at night, when have uncomfortable in chest suppress Gas, when have sigh, no hemoptysis, no pectoralgia.Anti-inflammatory treatment is given, and gives we and takes orally, is evaluated after 1 week, cough and expectoration remission, Occasionally there is cough on daytime, slight chest distress deactivates anti-inflammation drugs.Follow-up after following the service 1 month, patient experiences stable disease, when have daytime Dry cough, slight chest distress.
Case 5: Mr. Wang, female, 60 years old, address was Shandong Province, city, the Xiajin County street Yin Cheng, resident, adenocarcinoma of lung, intrapulmonary Shift Bone tumour.Oral Gefitinib drug is so far.Existing pectoralgia, takes orally opioid analgesia drug by NRS6 points, and alimentary canal is bad anti- Ying great, nausea and vomiting, difference of receiving are imitated bad after antiemetic.Deactivate opium analgesics.Give the court's homemade traditional Chinese drug pain caused by cancer It is peaceful be applied with 5 days after, NRS is down to 4 points, and it is oral to give we, evaluate, NRS2 points, can tolerate after 1 week, patient without obvious digestion road not Good reaction.Follow-up in 1 month, patient experiences stable disease, pectoralgia symptom are relieved, and NRS0-1 points or so.
Case 6: Sun, male, 62 years old, address was Dezhou City Shandong Province Pingyuan County, retirement, small cell carcinoma of lung, intrapulmonary turn It moves, cranium brain transfer, Bone tumour.6 period of Etoposide+cisplatin chemotherapy is given, now has cough, irritation dry cough, night cough when patient It coughs obvious, no hemoptysis, no chest distress, no pectoralgia.After advising we to take 1 week, patient's cough symptom is clearly better, and when daytime has Occasionally there are cough, no chest distress, no chest at cough, day 5 times or so, night without cough, the following the service medicine, follow-up after 1 month, patient Bitterly, stable disease.
Case 7: Liu, male, 69 years old, address was Hebei province Gucheng County, resident, lung squamous cancer, mediastinal lymph node metastasis.It gives Lung cancer lesion stereotactic radiotherapy, and give taxol+4 period of lobaplatin chemotherapy, therapeutic evaluation SD.There is cough when showing patient still Expectoration, and blood-stained sputum block, no chest distress, no pectoralgia.And give we and take orally, it is evaluated after 1 week, cough and expectoration remission, Occasionally have a cough on daytime, no blood-stained sputum, follow-up after following the service 1 month, patient experiences stable disease, when have dry cough on daytime, no blood-stained sputum.
Case 8: Zhao so-and-so, male, 78 years old, address be Hebei province Jing County, resident, adenocarcinoma of lung, pleural effusion.It is not antitumor to control It treats.Have a cough and expectoration now, cough spits the viscous phlegm of white, and occasionally there is a cough at night, when have chest distress, about 50 meters of walking i.e. sense is felt suffocated, Without hemoptysis, no pectoralgia.And it is oral to give we, evaluates after 1 week, cough and expectoration remission, occasionally there is a cough on daytime, chest distress compared with Preceding improvement, walking about 200m sense are felt suffocated.Follow-up after following the service 1 month, patient experiences stable disease, when have dry cough on daytime, it is slight uncomfortable in chest to suppress Gas can walk to 500m.
The invention belongs to then make clearing lung-heatization product side by oneself, patients with lung cancer cough and expectoration, chest distress, pectoralgia can be obviously improved Etc. clinical symptoms, reduce abuse of antibiotics and analgesic drug product application bring adverse reaction.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (5)

1. a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, it is characterised in that: including radix scutellariae, adlay, cordate houttuynia, Field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., it is above-mentioned Each raw material is respectively according to poidometer, radix scutellariae 15-21g, adlay 9-12g, cordate houttuynia 9-15g, field pennycress 9-15g, trigone 6-9g, Curcuma zedoary 6-9g, bombyx batryticatus 6-9g, pheretima 6-9g, tuber of pinellia 9-15g, dried orange peel 9-15g, Radix Paeoniae Alba 9-15g, Radix Angelicae Sinensis 9-15g, Prunella vulgaris 9- 15g, oldenlandia diffusa 15-30g, Radix Glycyrrhizae 6-15g.
2. according to claim 1 a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, it is characterised in that: packet Include radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, white flower HERBA HEDYOTIS DIFFUSAE and Radix Glycyrrhizae etc., above-mentioned each raw material be respectively according to poidometer, radix scutellariae 16-20g, adlay 10-11g, cordate houttuynia 10-13g, Field pennycress 10-13g, trigone 7-8g, curcuma zedoary 7-8g, bombyx batryticatus 7-8g, pheretima 7-8g, tuber of pinellia 10-13g, dried orange peel 10-14g, Radix Paeoniae Alba 10-14g, Radix Angelicae Sinensis 10-13g, Prunella vulgaris 10-13g, oldenlandia diffusa 18-27g, Radix Glycyrrhizae 8-12g.
3. according to claim 1 or 2 a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, feature exists In: it is withered including radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, summer Grass, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned each raw material is respectively radix scutellariae 18g, adlay 11g, cordate houttuynia 12g, to lose according to poidometer Sauce grass 12g, trigone 8g, curcuma zedoary 8g, bombyx batryticatus 8g, pheretima 8g, tuber of pinellia 12g, dried orange peel 11g, Radix Paeoniae Alba 12g, Radix Angelicae Sinensis 11g, Prunella vulgaris 11g, oldenlandia diffusa 23g, Radix Glycyrrhizae 10g.
4. according to claim 1 a kind of for treating the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, it is characterised in that: packet Include radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, the tuber of pinellia, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, white flower HERBA HEDYOTIS DIFFUSAE and Radix Glycyrrhizae etc., above-mentioned each raw material according to poidometer be respectively as follows: radix scutellariae 15g, adlay 9g, cordate houttuynia 15g, field pennycress 15g, Trigone 9g, curcuma zedoary 9g, bombyx batryticatus 9g, pheretima 6g, tuber of pinellia 9g, dried orange peel 9g, Radix Paeoniae Alba 9g, Radix Angelicae Sinensis 9g, Prunella vulgaris 15g, oldenlandia diffusa 30g, Radix Glycyrrhizae 8g.
5. it is according to claim 1 a kind of for treating the preparation method of the Chinese medicine composition of syndrome of intermin-gled phlegm and blood stasis lung cancer, It is characterized in that: including the following steps, firstly, by radix scutellariae, adlay, cordate houttuynia, field pennycress, trigone, curcuma zedoary, bombyx batryticatus, pheretima, half Summer, dried orange peel, Radix Paeoniae Alba, Radix Angelicae Sinensis, Prunella vulgaris, oldenlandia diffusa and Radix Glycyrrhizae etc., above-mentioned Chinese medicine are put into casserole, and add water 1000ml, are needed Cover Chinese medicine, impregnate 20 minutes, need to stir frequently during bubble, after put to boiling on fire;High fire is used before enduring out, Switch to small fire after enduring out slowly to endure, small fire is endured 20 minutes, and medical fluid is then filtered out;Again plus 500ml temperature is that 60 DEG C of water are used as medicine Slag continues high fire and endures out, after switch to small fire and slowly endure 20 minutes, filter out medical fluid again;Medical fluid is uniformly mixed twice, is divided into two etc. Part, it warmly takes sooner or later each primary.
CN201811651609.XA 2018-12-31 2018-12-31 It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer Pending CN109481609A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811651609.XA CN109481609A (en) 2018-12-31 2018-12-31 It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811651609.XA CN109481609A (en) 2018-12-31 2018-12-31 It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer

Publications (1)

Publication Number Publication Date
CN109481609A true CN109481609A (en) 2019-03-19

Family

ID=65713678

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811651609.XA Pending CN109481609A (en) 2018-12-31 2018-12-31 It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer

Country Status (1)

Country Link
CN (1) CN109481609A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332393A (en) * 2021-06-03 2021-09-03 丁金泉 Prescription of "Changqi" refined ointment for treating tumor and its preparing process
CN114344434A (en) * 2022-02-18 2022-04-15 南京中医药大学 Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101209334A (en) * 2007-12-25 2008-07-02 孙绍彬 Lung cancer-treating medicament and preparation thereof
CN103169904A (en) * 2013-02-26 2013-06-26 孙胜波 Traditional Chinese medicine composition for treating lung cancer
CN106390026A (en) * 2016-10-28 2017-02-15 李爱伏 Traditional Chinese medicine treatment composition aiming at middle and late period primary lung cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101209334A (en) * 2007-12-25 2008-07-02 孙绍彬 Lung cancer-treating medicament and preparation thereof
CN103169904A (en) * 2013-02-26 2013-06-26 孙胜波 Traditional Chinese medicine composition for treating lung cancer
CN106390026A (en) * 2016-10-28 2017-02-15 李爱伏 Traditional Chinese medicine treatment composition aiming at middle and late period primary lung cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
瞿岳云: "《中医专方全书(珍藏本)豪华精装版》", 31 January 2018, 湖南科学技术出版社 *
马湃等: "《肿瘤》", 31 May 2005, 济南出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332393A (en) * 2021-06-03 2021-09-03 丁金泉 Prescription of "Changqi" refined ointment for treating tumor and its preparing process
CN114344434A (en) * 2022-02-18 2022-04-15 南京中医药大学 Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof

Similar Documents

Publication Publication Date Title
CN101745065B (en) Pharmaceutical composition with effects of resisting cancer and alleviating pain
CN103041317B (en) A kind of Chinese medicine composition for the treatment of tumor and preparation method thereof
CN109481609A (en) It is a kind of for treating the Chinese medicine composition and preparation method of syndrome of intermin-gled phlegm and blood stasis lung cancer
CN104043057A (en) Traditional Chinese medicinal composition for treating lymph cancer
CN105213974A (en) One treats lymphadenomatous Chinese medicine composition and application thereof
CN101085269B (en) Internal-applied traditional Chinese medicine composition for treating lung cancer
CN101856446B (en) Chinese medicinal composition for treating costalgia
CN104548141A (en) Digestive tract contrast agent having effect of treating gastrointestinal ulcer and good smearing effect
CN102671070A (en) Traditional Chinese medicine composition for treating cancers or tumors
CN102698114B (en) Chinese medicinal composition comprising Radix Scutellariae for treating tympanites, and preparation method thereof
CN110368440A (en) Alleviate the Chinese medicine composition and preparation method thereof of side effect of digestive tract
CN109528976A (en) It is a kind of for treating the Chinese medicine composition and preparation method of body surface metastatic tumor
CN103893603A (en) Medicine for treating radiation proctitis and preparation method
CN103520341A (en) Traditional Chinese medicine prescription used for treating esophageal cancer
CN101940643B (en) Medicament for treating gastric cancer and esophagus cancer
CN114533831B (en) Traditional Chinese medicine composition with effects of warming middle-jiao, dispelling cold, eliminating dampness, promoting blood circulation, removing obstruction in channels and relieving pain and heat-covered bag thereof
CN102716191A (en) Poria cocos traditional Chinese herbal preparation for treating tympanites and method for preparing poria cocos traditional Chinese herbal preparation
CN105641422A (en) Traditional Chinese medicine decoction for treating hyperthyroidism
CN105250701A (en) Natural Chinese herbal medicine for treating phthisis
CN105412679A (en) Traditional Chinese medicine preparation for treating lung abscess and preparation method thereof
CN104138518B (en) Chinese herb preparation for treating septicemia at initial stage and preparation method thereof
CN103735999A (en) Traditional Chinese medicinal preparation for treating gout and preparation method thereof
CN105395872A (en) Spleen strengthening and stomach harmonizing oral liquid for resisting chemotherapy side reaction
CN103100012B (en) Traditional Chinese medicine composition for treating cardiac carcinoma
CN103027986B (en) Traditional Chinese medicine ointment for treating tumors

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20190319