CN109481342A - 玻尿酸面膜及其制造方法 - Google Patents
玻尿酸面膜及其制造方法 Download PDFInfo
- Publication number
- CN109481342A CN109481342A CN201811531643.3A CN201811531643A CN109481342A CN 109481342 A CN109481342 A CN 109481342A CN 201811531643 A CN201811531643 A CN 201811531643A CN 109481342 A CN109481342 A CN 109481342A
- Authority
- CN
- China
- Prior art keywords
- phase materials
- total weight
- weight
- face mask
- hyaluronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims abstract description 22
- 229920002674 hyaluronan Polymers 0.000 title claims abstract description 22
- 229960003160 hyaluronic acid Drugs 0.000 title claims abstract description 22
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 11
- 239000000463 material Substances 0.000 claims abstract description 107
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 16
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 16
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 16
- 239000000758 substrate Substances 0.000 claims abstract description 15
- 230000008595 infiltration Effects 0.000 claims abstract description 6
- 238000001764 infiltration Methods 0.000 claims abstract description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 33
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 30
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 22
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 20
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 19
- -1 hydroxy phenylpropionyl Chemical group 0.000 claims description 13
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 12
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 claims description 12
- 235000011399 aloe vera Nutrition 0.000 claims description 12
- 229920001577 copolymer Polymers 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- WSGCRSMLXFHGRM-DEVHWETNSA-N (2s)-2-[[(2s)-6-amino-2-[[(2s,3r)-2-[[(2s,3r)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid Chemical group CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O WSGCRSMLXFHGRM-DEVHWETNSA-N 0.000 claims description 11
- 239000005711 Benzoic acid Substances 0.000 claims description 11
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims description 11
- 108010087806 Carnosine Proteins 0.000 claims description 11
- 229920001503 Glucan Polymers 0.000 claims description 11
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims description 11
- 235000010233 benzoic acid Nutrition 0.000 claims description 11
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 11
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims description 11
- 229940044199 carnosine Drugs 0.000 claims description 11
- TWNIBLMWSKIRAT-VFUOTHLCSA-N levoglucosan Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@H]2CO[C@@H]1O2 TWNIBLMWSKIRAT-VFUOTHLCSA-N 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000001243 zingiber officinale rosc. root absolute Substances 0.000 claims description 11
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 10
- 108010068370 Glutens Proteins 0.000 claims description 10
- 235000001855 Portulaca oleracea Nutrition 0.000 claims description 10
- 241000219304 Portulacaceae Species 0.000 claims description 10
- 241000209140 Triticum Species 0.000 claims description 10
- 235000021307 Triticum Nutrition 0.000 claims description 10
- 150000001412 amines Chemical class 0.000 claims description 10
- 235000021312 gluten Nutrition 0.000 claims description 10
- 229940051250 hexylene glycol Drugs 0.000 claims description 10
- 229940104261 taurate Drugs 0.000 claims description 10
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 10
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 9
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 9
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 9
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 8
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 8
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 8
- 229940036350 bisabolol Drugs 0.000 claims description 8
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 8
- ZGSCRDSBTNQPMS-UJURSFKZSA-N 3-O-Ethylascorbic acid Chemical compound CCOC1=C(O)C(=O)O[C@@H]1[C@@H](O)CO ZGSCRDSBTNQPMS-UJURSFKZSA-N 0.000 claims description 7
- 229940120145 3-o-ethylascorbic acid Drugs 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 5
- 239000006185 dispersion Substances 0.000 claims description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 4
- 235000010323 ascorbic acid Nutrition 0.000 claims description 4
- 229960005070 ascorbic acid Drugs 0.000 claims description 4
- 239000011668 ascorbic acid Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 3
- 238000012797 qualification Methods 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- WNJCXXCSCHKPRY-UHFFFAOYSA-N azanium 2-(dimethylamino)ethanesulfonate Chemical compound [NH4+].CN(C)CCS([O-])(=O)=O WNJCXXCSCHKPRY-UHFFFAOYSA-N 0.000 claims description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 2
- 244000186892 Aloe vera Species 0.000 claims 3
- 230000001815 facial effect Effects 0.000 abstract description 8
- 239000000419 plant extract Substances 0.000 abstract description 4
- 230000003712 anti-aging effect Effects 0.000 abstract description 3
- 230000001153 anti-wrinkle effect Effects 0.000 abstract description 3
- 230000003020 moisturizing effect Effects 0.000 abstract description 3
- 238000003672 processing method Methods 0.000 abstract description 2
- 244000144927 Aloe barbadensis Species 0.000 description 9
- OGNHOGPWQTWKGQ-VGWMRTNUSA-N (2S)-5-amino-2-[[(2S)-1-[2-[[(2S)-5-amino-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid Chemical compound NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N1[C@H](C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 OGNHOGPWQTWKGQ-VGWMRTNUSA-N 0.000 description 5
- 230000003750 conditioning effect Effects 0.000 description 4
- 241000195493 Cryptophyta Species 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000004909 Moisturizer Substances 0.000 description 2
- 125000002252 acyl group Chemical group 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002906 microbiologic effect Effects 0.000 description 2
- 230000001333 moisturizer Effects 0.000 description 2
- 244000228367 Lewisia rediviva Species 0.000 description 1
- 235000007279 Lewisia rediviva Nutrition 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 125000004464 hydroxyphenyl group Chemical group 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
本发明涉及一种面膜及其制造方法，尤其是一种玻尿酸面膜及其加工方法。该面膜包括基材及浸润与基材中的敷料，其特征在于：所述的敷料按重量计包括A相物料90.87‑94.47％、B相物料0.82‑0.98％、C相物料4.46‑8.06％、D相物料0.09‑0.25％。本发明的玻尿酸面膜及其制造方法通过多相物料的组配，结合玻尿酸和多种特殊的植物提取成分，并根据各种植物提取成分的特性分组配比及加工，实现保湿、祛皱、抗衰、紧致肌肤的综合作用。
Description
技术领域
本发明涉及一种面膜及其制造方法，尤其是一种玻尿酸面膜及其加工方法。
背景技术
面膜是一种常用的改善脸部皮肤的护肤品，现在的面膜包括很多成分种类，其中，玻尿酸面膜是一个重要的分类，玻尿酸是一种透明质酸，可以保持皮肤的柔软度和弹性，所以使用玻尿酸面膜可以在面部加强营养物质的供给，保持皮肤弹性，延缓皱纹产生。现有的玻尿酸面膜在保湿效果外一般效果比较单一，往往不能综合的对皮肤缺陷进行护理。
发明内容
本发明的目的之一是提供一种既能够发挥玻尿酸的有效作用、又加入天然植物成分辅助调理、消炎等效果的玻尿酸面膜。
该面膜包括基材及浸润与基材中的敷料，其特征在于：所述的敷料按重量计包括A相物料90.87-94.47％、B相物料0.82-0.98％、C相物料4.46-8.06％、D相物料0.09-0.25％；其中，
A相物料按总重量计包括水76.77-78.57％、丁二醇3.7-4.3％、丙二醇5.7-6.3％、甘油4.7-5.3％；
B相物料按总重量计包括库拉索芦荟0.08-0.12％、燕麦β-葡聚糖0.28-0.32％、海藻糖0.18-0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28-0.32％；
C相物料按总重量计包括透明质酸钠0.15-0.25％、小麦蛋白0.05-0.15％、马齿苋3.53-6.47％、对羟基苯乙酮0.25-0.35％、己二醇0.25-0.35％、1/2-戊二醇0.025-0.075％、羟苯基丙酰胺苯甲酸0.005-0.015％、红没药醇0.15-0.25％、姜根提取物0.05-0.15％；
D相物料按总重量计包括棕榈酰五肽0.005-0.015％、六肽-90.005-0.015％、肌肽0.03-0.07％、3-o-乙基抗环血酸0.05-0.15％。
优选地，所述的A相物料按重量计占总量92.67％，其中按总重量计包含水77.67％、丁二醇4％、丙二醇6％、甘油6％；
优选地，所述的B相物料按重量计占总量0.9％，其中按总重量计包括库拉索芦荟0.1％、燕麦β-葡聚糖0.3％、海藻糖0.2％、丙烯酰二甲基牛磺酸铵/VP共聚物0.3％；
优选地，所述的C相物料按重量计占总量6.26％，其中，包括透明质酸钠0.2％、小麦蛋白0.1％、马齿苋5％、对羟基苯乙酮0.3％、己二醇0.3％、1/2-戊二醇0.05％、羟苯基丙酰胺苯甲酸0.01％、红没药醇0.2％、姜根提取物0.1％。
优选地，所述的D相物料按重量计占总量0.17％，其中，包括按总重量计包括棕榈酰五肽0.01％、六肽-9 0.01％、肌肽0.05％、3-o-乙基抗环血酸0.1％。
本发明还提供一种玻尿酸面膜制造方法，其特征在于：包括如下步骤：
S1、A相物料处理：乳化锅中加入A相物料，搅拌均匀分散完全后，高速搅拌分散均匀，然后搅拌升温至80-85℃；
S2、B相物料处理：加入B相物料，搅拌保温20min左右，确保溶解完全；
S3、C相物料处理：降温至43-45℃，加入C组物料,搅拌均匀。
S4、D相物料处理：继续降温至40℃以下，加入D组物料，慢速搅拌均匀；
S5、检验过滤：取料检验，合格后过滤出料，得到敷料；
S6、敷料浸润基材，包装、喷码；
其中，所述的敷料按重量计包括A相物料90.87-94.47％、B相物料0.82-0.98％、C相物料4.46-8.06％、D相物料0.09-0.25％；其中，
A相物料按总重量计包括水76.77-78.57％、丁二醇3.7-4.3％、丙二醇5.7-6.3％、甘油4.7-5.3％；
B相物料按总重量计包括库拉索芦荟0.08-0.12％、燕麦β-葡聚糖0.28-0.32％、海藻糖0.18-0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28-0.32％；
C相物料按总重量计包括透明质酸钠0.15-0.25％、小麦蛋白0.05-0.15％、马齿苋3.53-6.47％、对羟基苯乙酮0.25-0.35％、己二醇0.25-0.35％、1/2-戊二醇0.025-0.075％、羟苯基丙酰胺苯甲酸0.005-0.015％、红没药醇0.15-0.25％、姜根提取物0.05-0.15％；
D相物料按总重量计包括棕榈酰五肽0.005-0.015％、六肽-90.005-0.015％、肌肽0.03-0.07％、3-o-乙基抗环血酸0.05-0.15％。
本发明的玻尿酸面膜及其制造方法通过多相物料的组配，结合玻尿酸和多种特殊的植物提取成分，并根据各种植物提取成分的特性分组配比及加工，实现保湿、祛皱、抗衰、紧致肌肤的综合作用。
具体实施方式
本发明的实施例中由于取值范围变化较小，所以先在第一实施例和第二实施例中以端值为取值说明各个具体成分的配比，其中第一实施例的玻尿酸面膜包括基材及浸润与基材中的敷料，所述的敷料按重量计包括A相物料90.87％、B相物料0.82％、C相物料8.06％、D相物料0.25％；其中，
A相物料按总重量计包括水76.77％、丁二醇3.7％、丙二醇5.7％、甘油4.7％；
B相物料按总重量计包括库拉索芦荟0.08％、燕麦β-葡聚糖0.28％、海藻糖0.18％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28％；
C相物料按总重量计包括透明质酸钠0.25％、小麦蛋白0.15％、马齿苋6.47％、对羟基苯乙酮0.35％、己二醇0.35％、1/2-戊二醇0.075％、羟苯基丙酰胺苯甲酸0.015％、红没药醇0.25％、姜根提取物0.15％；
D相物料按总重量计包括棕榈酰五肽0.015％、六肽-9 0.015％、肌肽0.07％、3-o-乙基抗环血酸0.15％。
第二实施例中的玻尿酸面膜包括基材及浸润与基材中的敷料，所述的敷料按重量计包括A相物料94.47％、B相物料0.98％、C相物料4.46％、D相物料0.09％；其中，
A相物料按总重量计包括水78.57％、丁二醇4.3％、丙二醇6.3％、甘油5.3％；
B相物料按总重量计包括库拉索芦荟0.12％、燕麦β-葡聚糖0.32％、海藻糖0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.32％；
C相物料按总重量计包括透明质酸钠0.15％、小麦蛋白0.05％、马齿苋3.53％、对羟基苯乙酮0.25％、己二醇0.25％、1/2-戊二醇0.02％、羟苯基丙酰胺苯甲酸0.005％、红没药醇0.15％、姜根提取物0.05％；
D相物料按总重量计包括棕榈酰五肽0.005％、六肽-9 0.005％、肌肽0.03％、3-o-乙基抗环血酸0.05％。
在第三实施例中，以上述端值的中间值为例说明配比组成，该中间值配比为最优实施例，第二实施例中的玻尿酸面膜包括基材及浸润与基材中的敷料，所述的敷料按重量计包括：
A相物料按重量计占总量92.67％，其中按总重量计包含水77.67％、丁二醇4％、丙二醇6％、甘油6％；
B相物料按重量计占总量0.9％，其中按总重量计包括库拉索芦荟0.1％、燕麦β-葡聚糖0.3％、海藻糖0.2％、丙烯酰二甲基牛磺酸铵/VP共聚物0.3％；
C相物料按重量计占总量6.26％，其中，包括透明质酸钠0.2％、小麦蛋白0.1％、马齿苋5％、对羟基苯乙酮0.3％、己二醇0.3％、1/2-戊二醇0.05％、羟苯基丙酰胺苯甲酸0.01％、红没药醇0.2％、姜根提取物0.1％。
D相物料按重量计占总量0.17％，其中，包括按总重量计包括棕榈酰五肽0.01％、六肽-9 0.01％、肌肽0.05％、3-o-乙基抗环血酸0.1％。
本发明的第四实施例提供一种玻尿酸面膜制造方法，包括如下步骤：
S1、A相物料处理：乳化锅中加入A相物料，搅拌均匀分散完全后，高速搅拌分散均匀，然后搅拌升温至80-85℃；
S2、B相物料处理：加入B相物料，搅拌保温20min左右，确保溶解完全；
S3、C相物料处理：降温至43-45℃，加入C组物料,搅拌均匀。
S4、D相物料处理：继续降温至40℃以下，加入D组物料，慢速搅拌均匀；
S5、检验过滤：取料检验，合格后过滤出料，得到敷料；
S6、敷料浸润基材，包装、喷码；
其中，所述的敷料按重量计包括A相物料90.87-94.47％、B相物料0.82-0.98％、C相物料4.46-8.06％、D相物料0.09-0.25％；其中，
A相物料按总重量计包括水76.77-78.57％、丁二醇3.7-4.3％、丙二醇5.7-6.3％、甘油4.7-5.3％；
B相物料按总重量计包括库拉索芦荟0.08-0.12％、燕麦β-葡聚糖0.28-0.32％、海藻糖0.18-0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28-0.32％；
C相物料按总重量计包括透明质酸钠0.15-0.25％、小麦蛋白0.05-0.15％、马齿苋3.53-6.47％、对羟基苯乙酮0.25-0.35％、己二醇0.25-0.35％、1/2-戊二醇0.025-0.075％、羟苯基丙酰胺苯甲酸0.005-0.015％、红没药醇0.15-0.25％、姜根提取物0.05-0.15％；
D相物料按总重量计包括棕榈酰五肽0.005-0.015％、六肽-90.005-0.015％、肌肽0.03-0.07％、3-o-乙基抗环血酸0.05-0.15％。
上述成分中，A相物料中的水7作为溶剂，丁二醇、丙二醇、甘油和D相物料中的棕榈酰五肽作为保湿剂；B相物料中库拉索芦荟、燕麦β-葡聚糖、海藻糖作为皮肤调理剂，丙烯酰二甲基牛磺酸铵/VP共聚物作为增稠剂，C相物料中的透明质酸钠作为保湿剂，其余皆作为皮肤调理剂；D相物料中除棕榈酰五肽外皆作为皮肤调理剂，其中A相物料主要作为保湿功用，B、C、D相物料主要起到祛皱、抗衰、紧致肌肤的综合作用。
B相物料按总重量计包括库拉索芦荟0.12％、燕麦β-葡聚糖0.32％、海藻糖0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.32％；
C相物料按总重量计包括透明质酸钠0.15％、小麦蛋白0.05％、马齿苋3.53％、对羟基苯乙酮0.25％、己二醇0.25％、1/2-戊二醇0.02％、羟苯基丙酰胺苯甲酸0.005％、红没药醇0.15％、姜根提取物0.05％；
D相物料按总重量计包括棕榈酰五肽0.005％、六肽-9 0.005％、肌肽0.03％、3-o-乙基抗环血酸0.05％。
基于上述各个实施例中所得的敷料特性为：颜色：无色；性状：透明粘稠液体；气味：植物清香。
由于各个实施例中的成分的取值比较接近，以下以第三实施例中的配比制造的面膜的实验数据为例进行说明具体的检验数据：
生产设备清单：
【卫生化学指标】
表2卫生化学指标
| 检测项目 | 指标 |
| 汞 | ≤1mg/kg |
| 铅 | ≤10mg/kg |
| 砷 | ≤2mg/kg |
| 镉 | ≤5mg/kg |
【微生物指标】
表3微生物指标
| 检测项目 | 指标 |
| 菌落总数 | ≤500CFU/g |
| 霉菌和酵母菌总数 | ≤100CFU/g |
| 粪大肠菌群 | 不得检出/g |
| 铜绿假单胞菌 | 不得检出/g |
| 金黄色葡萄球菌 | 不得检出/g |
【检验方法】
表4检验方法
以上所述仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书内容所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。
Claims (6)
1.玻尿酸面膜，包括基材及浸润与基材中的敷料，其特征在于：所述的敷料按重量计包括A相物料90.87-94.47％、B相物料0.82-0.98％、C相物料4.46-8.06％、D相物料0.09-0.25％；其中，
A相物料按总重量计包括水76.77-78.57％、丁二醇3.7-4.3％、丙二醇5.7-6.3％、甘油4.7-5.3％；
B相物料按总重量计包括库拉索芦荟0.08-0.12％、燕麦β-葡聚糖0.28-0.32％、海藻糖0.18-0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28-0.32％；
C相物料按总重量计包括透明质酸钠0.15-0.25％、小麦蛋白0.05-0.15％、马齿苋3.53-6.47％、对羟基苯乙酮0.25-0.35％、己二醇0.25-0.35％、1/2-戊二醇0.025-0.075％、羟苯基丙酰胺苯甲酸0.005-0.015％、红没药醇0.15-0.25％、姜根提取物0.05-0.15％；
D相物料按总重量计包括棕榈酰五肽0.005-0.015％、六肽-90.005-0.015％、肌肽0.03-0.07％、3-o-乙基抗环血酸0.05-0.15％。
2.如权利要求1所述的玻尿酸面膜，其特征在于：所述的A相物料按重量计占总量92.67％，其中按总重量计包含水77.67％、丁二醇4％、丙二醇6％、甘油6％。
3.如权利要求1所述的玻尿酸面膜，其特征在于：所述的B相物料按重量计占总量0.9％，其中按总重量计包括库拉索芦荟0.1％、燕麦β-葡聚糖0.3％、海藻糖0.2％、丙烯酰二甲基牛磺酸铵/VP共聚物0.3％。
4.如权利要求1所述的玻尿酸面膜，其特征在于：所述的C相物料按重量计占总量6.26％，其中，包括透明质酸钠0.2％、小麦蛋白0.1％、马齿苋5％、对羟基苯乙酮0.3％、己二醇0.3％、1/2-戊二醇0.05％、羟苯基丙酰胺苯甲酸0.01％、红没药醇0.2％、姜根提取物0.1％。
5.如权利要求1所述的玻尿酸面膜，其特征在于：所述的D相物料按重量计占总量0.17％，其中，包括按总重量计包括棕榈酰五肽0.01％、六肽-90.01％、肌肽0.05％、3-o-乙基抗环血酸0.1％。
6.玻尿酸面膜制造方法，其特征在于：包括如下步骤：
S1、A相物料处理：乳化锅中加入A相物料，搅拌均匀分散完全后，高速搅拌分散均匀，然后搅拌升温至80-85℃；
S2、B相物料处理：加入B相物料，搅拌保温20min左右，确保溶解完全；
S3、C相物料处理：降温至43-45℃，加入C组物料,搅拌均匀。
S4、D相物料处理：继续降温至40℃以下，加入D组物料，慢速搅拌均匀；
S5、检验过滤：取料检验，合格后过滤出料，得到敷料；
S6、敷料浸润基材，包装、喷码；
其中，所述的敷料按重量计包括A相物料90.87-94.47％、B相物料0.82-0.98％、C相物料4.46-8.06％、D相物料0.09-0.25％；其中，
A相物料按总重量计包括水76.77-78.57％、丁二醇3.7-4.3％、丙二醇5.7-6.3％、甘油4.7-5.3％；
B相物料按总重量计包括库拉索芦荟0.08-0.12％、燕麦β-葡聚糖0.28-0.32％、海藻糖0.18-0.22％、丙烯酰二甲基牛磺酸铵/VP共聚物0.28-0.32％；
C相物料按总重量计包括透明质酸钠0.15-0.25％、小麦蛋白0.05-0.15％、马齿苋3.53-6.47％、对羟基苯乙酮0.25-0.35％、己二醇0.25-0.35％、1/2-戊二醇0.025-0.075％、羟苯基丙酰胺苯甲酸0.005-0.015％、红没药醇0.15-0.25％、姜根提取物0.05-0.15％；
D相物料按总重量计包括棕榈酰五肽0.005-0.015％、六肽-90.005-0.015％、肌肽0.03-0.07％、3-o-乙基抗环血酸0.05-0.15％。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811531643.3A CN109481342A (zh) | 2018-12-14 | 2018-12-14 | 玻尿酸面膜及其制造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811531643.3A CN109481342A (zh) | 2018-12-14 | 2018-12-14 | 玻尿酸面膜及其制造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109481342A true CN109481342A (zh) | 2019-03-19 |
Family
ID=65710324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811531643.3A Pending CN109481342A (zh) | 2018-12-14 | 2018-12-14 | 玻尿酸面膜及其制造方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109481342A (zh) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040161435A1 (en) * | 2003-02-14 | 2004-08-19 | Gupta Shyam K. | Skin Firming Anti-Aging Cosmetic Mask Compositions |
| CN104739744A (zh) * | 2013-12-28 | 2015-07-01 | 大连美乐生物技术开发有限公司 | 一种紧致美白面膜及其制备方法 |
| CN105878048A (zh) * | 2016-03-30 | 2016-08-24 | 韩玉逍 | 一种多肽蚕丝面膜的制作方法 |
| CN106667870A (zh) * | 2017-01-19 | 2017-05-17 | 杭州心悦化妆品有限公司 | 一种面膜 |
| CN108478469A (zh) * | 2018-06-27 | 2018-09-04 | 孙涛 | 一种极润补水修护面膜 |
| CN108969435A (zh) * | 2018-08-16 | 2018-12-11 | 苏州火睿新材料科技有限公司 | 含富勒烯的修复营养面膜及其制备和使用方法 |
-
2018
- 2018-12-14 CN CN201811531643.3A patent/CN109481342A/zh active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040161435A1 (en) * | 2003-02-14 | 2004-08-19 | Gupta Shyam K. | Skin Firming Anti-Aging Cosmetic Mask Compositions |
| CN104739744A (zh) * | 2013-12-28 | 2015-07-01 | 大连美乐生物技术开发有限公司 | 一种紧致美白面膜及其制备方法 |
| CN105878048A (zh) * | 2016-03-30 | 2016-08-24 | 韩玉逍 | 一种多肽蚕丝面膜的制作方法 |
| CN106667870A (zh) * | 2017-01-19 | 2017-05-17 | 杭州心悦化妆品有限公司 | 一种面膜 |
| CN108478469A (zh) * | 2018-06-27 | 2018-09-04 | 孙涛 | 一种极润补水修护面膜 |
| CN108969435A (zh) * | 2018-08-16 | 2018-12-11 | 苏州火睿新材料科技有限公司 | 含富勒烯的修复营养面膜及其制备和使用方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Pereira dos Santos et al. | Chitosan/essential oils formulations for potential use as wound dressing: Physical and antimicrobial properties | |
| Khan et al. | Development of edible gelatin composite films enriched with polyphenol loaded nanoemulsions as chicken meat packaging material | |
| JP5503888B2 (ja) | 化粧品パック用ゲルシート | |
| CN103462843A (zh) | 一种温和护肤凝胶 | |
| EP2177220B1 (en) | Gel containing pirfenidone | |
| Pagano et al. | Development and characterization of xanthan gum and alginate based bioadhesive film for pycnogenol topical use in wound treatment | |
| Zarandona et al. | 3D printed chitosan-pectin hydrogels: From rheological characterization to scaffold development and assessment | |
| Carriço et al. | Design and characterization of a new quercus suber-based pickering emulsion for topical application | |
| CN103181861A (zh) | 泡泡面膜及其制作工艺 | |
| Spiridon et al. | Development and performance of bioactive compounds-loaded cellulose/collagen/polyurethane materials | |
| CN104416996B (zh) | 一种有球型石墨层的pet薄膜及其制备方法 | |
| US20110135746A1 (en) | Protective lip balm composition | |
| CN106118838A (zh) | 可稀释循环回收使用光伏硅晶片线切割液 | |
| CN104622778A (zh) | 一种沐浴露及其制备方法 | |
| CN109481342A (zh) | 玻尿酸面膜及其制造方法 | |
| Lupu et al. | Temperature induced gelation and antimicrobial properties of Pluronic F127 based systems | |
| Khattak et al. | Formulation, in vitro characterization and antibacterial activity of chitosan-decorated cream containing bacitracin for topical delivery | |
| CN104139625A (zh) | 一种具有杀菌功能的温和润版液及其制备方法 | |
| CN104139626B (zh) | 一种低刺激性润版液及其制备方法 | |
| CN104139631A (zh) | 一种含天然抗氧化剂的润版液及其制备方法 | |
| CN106243909A (zh) | 一种用于体育器材表面的高抗菌涂层的制备方法 | |
| CN104830180A (zh) | 一种水性防腐涂料 | |
| Kiseļova et al. | Analysis of Extemporaneous Prescriptions Prescribed by Dermatovenerologists in Latvia and Comparison with Standardized Compounded Preparation Monographs of Germany and USA | |
| CN103690403A (zh) | 一种具有生物杀菌消炎功能的剃须液及其制备方法 | |
| CN103766362B (zh) | 用于防治水稻病害的农药悬浮剂 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190319 |