CN109464498A - A kind of Chinese medicinal capsule for treating psoriasis - Google Patents

A kind of Chinese medicinal capsule for treating psoriasis Download PDF

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Publication number
CN109464498A
CN109464498A CN201910039898.6A CN201910039898A CN109464498A CN 109464498 A CN109464498 A CN 109464498A CN 201910039898 A CN201910039898 A CN 201910039898A CN 109464498 A CN109464498 A CN 109464498A
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parts
chinese medicinal
capsule
medicinal capsule
treating psoriasis
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CN201910039898.6A
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Inventor
史延雷
李天忠
孟现彬
谢斯涛
朱志华
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
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Abstract

A kind of Chinese medicinal capsule for treating psoriasis, matching according to prescription selects Chinese medicine to be processed into, prescription proportion includes 100 parts of radix euphorbiae lantu, 60 parts of indigo naturalis, 40 parts of the root of Dahurain angelica, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of licorice, 10 parts of borneol, it is milled into fine powder, is uniformly mixed, is dispensed into Capsules, each capsule is packed into fine powder 0.35-0.45g, Chinese medicinal capsule is made, is placed in container bottle, drying is protected from light storage.The present invention is for when treating psoriasis, 2-3 times oral daily, a Chinese medicinal capsule, plain boiled water to be taken every time.When diagnosis and treatment, according to the different physical condition of each patient and specific symptom, it is advised to take according to explanation.90% or more effective percentage, cure rate 80%.

Description

A kind of Chinese medicinal capsule for treating psoriasis
Technical field
The present invention relates to the drugs more particularly to Chinese medicinal capsule for the treatment of psoriasis.
Background technique
Psoriasis is a kind of common chronic inflammation skin disease, is commonly called as psoriasis, is mostly influenced, infected by h and E, Mental element, climatic factor, dietary factor can be used as inducement, inspire this disease, and characteristic skin damage is red papules or plate The multilayer silvery white scales of skin that peel off is born on block, often feels itch.Common treatment method be generally oral vitamin A, vitamin C, aminophylline, Cimetidine, intramuscular injection 654-2 injection etc. or compound Danshen Root 16ml are dissolved in 5% glucose or Dextran 5 00ml, and intravenous infusion is every Day is primary, is used in conjunction 20-30 days.Part applies Ta Zhaluo and orders ointment progress external treatment simultaneously.Although these methods can be effectively The table disease of psoriasis is treated, but has used chemicals after all, treatment is more troublesome, is easy to produce dependence, and the time is long It will appear repeatedly, effect is not also fairly obvious.
Summary of the invention
The purpose of the present invention, be exactly on the basis of existing pharmacological research, using tcm methods to patient's human body itself into Row conditioning removes toxin, fundamentally improves autoimmunity from the inside to the outside, plays the role for the treatment of psoriasis.
The task of the present invention is what is completed in this way: studying a kind of Chinese medicinal capsule for treating psoriasis, matches and select according to prescription Be processed into Chinese medicine, prescription proportion include 100 parts of radix euphorbiae lantu, 60 parts of indigo naturalis, 40 parts of the root of Dahurain angelica, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of licorice, 10 parts of borneol, it is milled into fine powder, is uniformly mixed, is dispensed into Capsules, each capsule is packed into fine powder 0.35-0.45g, Chinese medicinal capsule is made, is placed in container bottle, drying is protected from light storage.When for treating psoriasis, 2-3 is taken orally daily according to explanation Secondary, a Chinese medicinal capsule, plain boiled water take every time.
The Chinese medicine that prescription proportion of the present invention is selected respectively has feature: radix euphorbiae lantu bitter, property is pungent flat, very toxic, distributed in lung channel, there is row Blood breaks phlegm, dissolving phlegm disinsection efficiency, can control malignant sore stubborn dermatitis；Indigo naturalis taste cold in nature is salty, return lung stomach meridian, has clearing heat and detoxicating, blood cooling and ecchymoses removing Function；Radix Salviae Miltiorrhizae bitter cold nature, has the function of activating blood circulation and dissipating phlegm, controls scabies；Root of Dahurain angelica bitter is warm-natured, can dispel pathogenic wind and remove dampness, pungent-warm It is sensible；Borneol acrid flavour is cool, gas faint scent, can open hole powder stagnated fire；Licorice sweet in flavor and neutral in nature, return heart lung taste warp is clearing heat and detoxicating, and in Adjust all medicines.Select the above 6 taste Chinese medicines to form prescription proportion of the invention, have clearing heat and detoxicating, blood circulation and removing stasis, dispel pathogenic wind and remove dampness, Calm down antipruritic effect, complex treatment psoriasis.
When it is implemented, prescription according to the invention proportion selects each taste Chinese medicine, with medicinal material pulverizer by each taste Chinese medicine Material crushes to form smalls, is uniformly mixed, and is packed into Capsules, Chinese medicinal capsule of the present invention is made, takes treatment by patient.Experience Card, 90% or more effective percentage, cure rate 80% or so.
It manufactured experimently, tested according to above-mentioned technical proposal, it was demonstrated that rationally, production method is simple for prescription proportion of the invention, Convenient to take, applicable patients are in extensive range, achieve comparatively ideal curative effect in terms for the treatment of psoriasis, admirably achieve Predetermined purpose.
Specific embodiment
Below with reference to embodiment, a specific embodiment of the invention is illustrated.
When practical application, radix euphorbiae lantu 100g, indigo naturalis 60g, root of Dahurain angelica 40g, Radix Salviae Miltiorrhizae 30g, licorice 30g, borneol are selected every time 10g is milled into fine powder with the Chinese medicine material crushing machine of shop of Chinese medicines, is uniformly mixed, is dispensed into Capsules, and each capsule is packed into Chinese medicinal capsule of the present invention is made in fine powder 0.35-0,45g, is placed in container bottle, and drying is protected from light storage.When diagnosis and treatment, according to each The respective different physical condition of patient and specific symptom, advise it to take according to explanation.The present invention is for hepatic and kidney function obstacle, stomach And patient and the child patient of duodenal ulcer, it should all be used with caution.It is not taken by pregnant women.
Case 1, Mr. Wang, male, Liaocheng City Chiping County Leping town people from the village Shi Zhuan, on May 6th, 2012 is medical, Shi Nian 42 Year.Readme suffers from psoriasis 7 years, and local health clinics in towns and townships is treated with oral and external applied medicine, weight when state of an illness is light, again and again.It examines Treatment is shown in that whole body plays red patch, above covers the scales of skin that peel off, and fash color is scarlet, and majority has been linked to be piece, flush, and furfur is more.Diagnosis For psoriasis vulgaris, capsule 200 of the present invention are given.It advises and takes orally 2 daily, respectively take one after morning and evening dinner, be changed to after ten days 3 are taken daily, Morning Afternoon Evening respectively takes one after meal, and avoids eating tobacco and wine, the smelling of fish or mutton, maror.Current year further consultation on July 20, the scales of skin that peel off by It gradually falls off, skin lesion is thinning soft.200 capsules of the present invention are taken again, are continued oral according to explanation.It is examined within 1 day three to October current year, skin Restore normal.Continue capsule 200 of the present invention of clothes again to be consolidated, rear follow-up 1 year fully recovers, do not recur again.
Case 2, Lu so-and-so, female lives Liaocheng City Dongchangfu District dragon gulf cell, and on September 7th, 2015 are medical, Shi Nian 16 Year.Readme suffers from psoriasis 2 years, seeks medical advice through many places, and curative effect is not shown, diagnosis and treatment physical examination symptoms include, shirtfront back respectively has many places skin lesion, above covers The scales of skin that peel off is stripped off rear human body in dark brown, is relatively dried.It is diagnosed as psoriasis, gives capsule 60 of the present invention.It advises and takes orally 2 daily, One is respectively taken after morning and evening dinner.Current year further consultation on October 9, skin lesion obviously becomes smaller, and without the scales of skin that peel off, base color shoals, then gives this Invention capsule 100,3 are taken daily, Morning Afternoon Evening respectively takes one after meal.It is examined within 20 days three to November current year, private prosecution duration of medication has abdomen Phenomenon is rushed down, actually normal toxin expelling.Its skin lesion is seen without then taking 200 capsules of the present invention, consolidated, still by daily oral 2 Grain, respectively takes one after morning and evening dinner.Effect of follow-up visit by telephone after half a year, answer have been fully recovered, and restore normal.Instrucion avoids eating the peppery food of raw meat, continues Keep, after do not recur again.
Case 3, Feng so-and-so, male, Liaocheng City Guan County Xinji Feng Duzhuan people, on March 15th, 2008 is medical, Shi Nian 45 years old.From Tell illness 20 years, obstinate has been lost the confidence, and is come here through friend's introduction and is sought doctor.Through investigating, patient's incidence, on Lower limb, the back skin lesion of waist abdomen above cover the scales of skin that peel off, substrate flush up to 80% or more.It is diagnosed as red integumentary pattern psoriasis.Give glue of the present invention 200, capsule.It advises and takes orally 3 daily, Morning Afternoon Evening respectively takes one after meal, and avoids eating tobacco and wine, the smelling of fish or mutton, maror.May 25 current year Further consultation, range estimation four limbs are almost recovered, and waist abdomen back also takes an evident turn for the better.Give capsule 200 of the present invention again, administration is ditto not Become.It was examined to current year September 1 day three, each position has restored normally, to be almost recovered.Capsule 200 of the present invention are taken again, are consolidated and are controlled It treats, takes daily 2, respectively take one after morning and evening dinner.When end of the year Effect of follow-up visit by telephone, answer has been fully recovered, has not been recurred again.
Case 4, Mr. Wang, male, Yanggu County area just outside a city gate Zhen Cheng Jiao Xu people from village, on 2 8th, 2009 are medical, and Shi Nian 39 years old.Readme Illness is more than 3 years, and treatment is multiple, the inside and outside used many of drug, and curative effect is little.Physical examination, which is examined, to be seen, the big face of scalp, body trunk, four limbs Product skin lesion, surface cover the multilayer silvery white scales of skin that peel off, around have obvious blush, more after breakout.Conscious gargalesthesia is obvious.It is diagnosed as silver Bits disease.Give capsule 200 of the present invention.Oral 3 daily are advised, Morning Afternoon Evening respectively takes one after meal, and avoids eating the tobacco and wine, smelling of fish or mutton, pungent Peppery food.It is effective after one month, it is free from side effects, dosage is taken, and takes daily secondary, takes orally after morning and evening dinner, 2 tablets each time.To working as On July 20, three in examines, and sees body surface rehabilitation 90%, then take capsule 200 of the present invention, and decrement is taken, 2 oral daily, One is respectively taken after morning and evening dinner.Current year, Effect of follow-up visit by telephone, answer whole rehabilitations advised its season in spring and autumn according still further to each clothes of explanation by the end of October One month, consolidate to prevent recurrence.So far it does not recur again.
Case 5, Jiang, female, Hebei province, foundation town people from the village Gong Zhuan, Hengshui City Gucheng County, on November 17th, 2016 is medical, When year 56 years old.Readme illness more than ten years.Integrative therapy is multiple, and effect is unobvious.Physical examination, which is examined, to be seen, the full crown covers silvery white The scales of skin that peel off, sheet fall off, and trunk four limbs spread size fash, and silver bits increase after scratching, it is red to remove base coat colour by force, and have sieve-like Blutpunkte, chest and abdomen back fash is more, and part has been merged in flakes.Diagnosis is psoriasis vulgaris.Give capsule of the present invention 200.It advises and takes orally 3 daily, Morning Afternoon Evening respectively takes one after meal, and avoids eating tobacco and wine, the smelling of fish or mutton, maror.On 2 3rd, 2017 It calls and reflects the fruit that taken effect, surface symptom mitigates, and posts course for the treatment of capsule of the present invention 200, and continuation is taken according to explanation. Further consultation on May 18 in 2017 has 80% and restores normal, the still band illness of Shang You 20% or so, and takes the present invention of a course for the treatment of Capsule 200, decrement is taken, and takes daily 2 times, respectively takes 1 after morning and evening dinner daily.Medication treatment terminates, and when Effect of follow-up visit by telephone, replies Recovery from illness restores normal.Capsule 200 of the present invention are posted again, it is daily oral primary, one every time, for consolidating curative effect.So far not It recurs again.
Chinese medicinal capsule efficacy stability of the present invention, applicable psoriatic's range is wide, quick after taking, uneasy to recur, Production application is simple and convenient, has significant curative effect and good popularization and application foreground.

Claims (1)

1. a kind of Chinese medicinal capsule for treating psoriasis matches according to prescription and Chinese medicine is selected to be processed into, it is characterised in that prescription Proportion includes 100 parts of radix euphorbiae lantu, 60 parts of indigo naturalis, 40 parts of the root of Dahurain angelica, 30 parts of Radix Salviae Miltiorrhizae, 30 parts of licorice, 10 parts of borneol, is milled into fine powder End is uniformly mixed, is dispensed into Capsules, and each capsule is packed into fine powder 0.35-0,45g, and Chinese medicinal capsule is made, and merging is held In device bottle, drying is protected from light storage, 2-3 times oral daily according to explanation when for treating psoriasis, every time a Chinese medicinal capsule, Plain boiled water takes.
CN201910039898.6A 2019-01-16 2019-01-16 A kind of Chinese medicinal capsule for treating psoriasis Pending CN109464498A (en)

Priority Applications (1)

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CN201910039898.6A CN109464498A (en) 2019-01-16 2019-01-16 A kind of Chinese medicinal capsule for treating psoriasis

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101322802A (en) * 2008-07-10 2008-12-17 马连光 Paste for curing psoriasis and preparation thereof
CN102247433A (en) * 2010-05-19 2011-11-23 郑秀琴 'Compound astragalus paste' navel plaster Chinese medicinal powder for treating psoriasis
CN102885943A (en) * 2011-07-22 2013-01-23 潘健 External Chinese medicinal liniment for treating psoriasis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101322802A (en) * 2008-07-10 2008-12-17 马连光 Paste for curing psoriasis and preparation thereof
CN102247433A (en) * 2010-05-19 2011-11-23 郑秀琴 'Compound astragalus paste' navel plaster Chinese medicinal powder for treating psoriasis
CN102885943A (en) * 2011-07-22 2013-01-23 潘健 External Chinese medicinal liniment for treating psoriasis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
郭玉波: "复方狼毒胶囊治疗银屑病250例观察", 《河北中医》 *

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Application publication date: 20190315