CN109439511A - A kind of biological material extraction element - Google Patents
A kind of biological material extraction element Download PDFInfo
- Publication number
- CN109439511A CN109439511A CN201811353770.9A CN201811353770A CN109439511A CN 109439511 A CN109439511 A CN 109439511A CN 201811353770 A CN201811353770 A CN 201811353770A CN 109439511 A CN109439511 A CN 109439511A
- Authority
- CN
- China
- Prior art keywords
- tube body
- biological material
- lumen
- extraction element
- material extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000012620 biological material Substances 0.000 title claims abstract description 27
- 238000000605 extraction Methods 0.000 title claims abstract description 23
- 238000005070 sampling Methods 0.000 claims abstract description 39
- 239000002274 desiccant Substances 0.000 claims abstract description 20
- 238000005192 partition Methods 0.000 claims description 12
- 238000005452 bending Methods 0.000 claims description 5
- 239000002250 absorbent Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002845 discoloration Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 238000001712 DNA sequencing Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002216 antistatic agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of biological material extraction elements, including the tube body with lumen and it is located at the intracorporal sampling swab of the pipe, the upper opening being connected to the lumen is offered on the top of the tube body, cooperation is equipped with a upper cover plug in the upper opening, and the upper cover plug, which is located on described intraluminal one end, is detachably connected the sampling swab；There is an accommodating chamber, the accommodating chamber is connected to by several air holes of the upper cover beyond the Great Wall with the lumen, and is built-in with desiccant in the upper cover plug.Desiccant built in the biological material extraction element not will increase tube body volume, and desiccant and extracting solution are encapsulated in same tube body.
Description
Technical field
The present invention relates to biological material extractive technique more particularly to a kind of biological material extraction elements.
Background technique
With the development of DNA sequencing technology, a large amount of criminal, civil cases, DNA have tracked down by DNA technique in public security organ
Technology plays increasingly important role fighting crime, protect in the work such as people's property safety.
In scene of a crime, for it is most of can not the contact biological material directly in kind that extracted, wiped usually using sampling
Son is extracted and is shifted as carrier, for example wipes or dip bloodstain with sampling swab.In the prior art, sampling swab
General and desiccant is encapsulated in together in same tube body, forms sampling pipe sleeve, and the effect of desiccant is the intracorporal steam of suction pipe,
The aridity for keeping lumen prevents mildew and bacterial growth, but desiccant is encapsulated in tube body undoubtedly will increase and is entirely taken
The volume of sample pipe sleeve is not easy to public security legal medical expert and carries.
In addition, public security legal medical expert when extracting biological material, needs first to dip extracting solution with sampling swab, allow on sampling swab
Swab head draw enough extracting solutions, wiping then is carried out to sampling point again and obtains biological material, existing extracting solution is past
Toward needing individually to carry, not only inconvenience, is also easy to omit.It is another in the prior art, have a kind of by sampling swab and extraction
Liquid is encapsulated in the intracorporal sampling pipe sleeve of same pipe together, although easy to carry, swab head is usually cotton or flocking, this
The sampling swab long period of soaking in pipe sleeve is sampled in extracting solution, be easy to make swab head have not been used just be immersed it is bad.
Moreover, desiccant and extracting solution can not be encapsulated in simultaneously in same tube body.
Summary of the invention
In order to solve above-mentioned the deficiencies in the prior art, the present invention provides a kind of biological material extraction element, built-in drying
Agent not will increase tube body volume, and desiccant and extracting solution are encapsulated in same tube body.
The technical problems to be solved by the invention are achieved by the following technical programs:
A kind of biological material extraction element including the tube body with lumen and is located at the intracorporal sampling swab of the pipe, institute
The upper opening for offering on the top of tube body and being connected to the lumen is stated, cooperation is equipped with a upper cover plug in the upper opening, described
Upper cover plug, which is located on described intraluminal one end, is detachably connected the sampling swab；There is an accommodating chamber in the upper cover plug,
The accommodating chamber is connected to by several air holes of the upper cover beyond the Great Wall with the lumen, and is built-in with desiccant.
Further, the desiccant is the water-absorbent material with humidity indicative function.
Further, the secondary opening of one be connected to the accommodating chamber is offered on the top surface of the upper cover plug, the pair is opened
Cooperation is equipped with a secondary lid plug on mouth.
Further, the upper cover plug includes interconnecting piece and handle portion, the connecting portion in the lumen for connecting
The sampling swab is connect, the handle position is used to take for user in outside the lumen.
Further, a partition panel is provided in the lumen, lumen partition is not connected to mutually by the partition panel
Epicoele and cavity of resorption, the upper opening is connected to the epicoele, and the sampling swab is arranged；It is offered on the bottom of the tube body
The pair being connected to the cavity of resorption is open, and cooperation is intracavitary under described to be provided with extracting solution equipped with a lower cover plug in the secondary opening.
Further, it is attached between the lower cover plug and tube body by a flexible connecting member, the flexible connecting member
The lower cover plug plug can be made on the under shed after bending fold.
Further, the flexible connecting member includes one that a lantern ring and both ends are connect with the lantern ring and lower cover plug respectively
Connection strap, the lantern ring are sheathed on the outer wall of the lower opening of the tube body, and the connection strap can flexible bending folding.
Further, the tube body is antistatic part.
Further, there is an at least plane on the outer surface of the tube body.
Further, the outer surface of the tube body is frosting.
The invention has the following beneficial effects: the biological material extraction elements to empty the solid space in the upper cover plug
The accommodating chamber is formed, then the desiccant is encapsulated in the accommodating chamber in the upper cover plug, is taken full advantage of on described
The inner space for covering plug is carried without increasing the tube body volume convenient for public security legal medical expert.
Detailed description of the invention
Fig. 1 is the schematic diagram of biological material extraction element provided by the invention；
Fig. 2 is the schematic diagram of lower cover plug and flexible connecting member provided by the invention.
Specific embodiment
The present invention will be described in detail with reference to the accompanying drawings and examples.
As shown in Figure 1, a kind of biological material extraction element, including the tube body 1 with lumen and is located in the tube body 1
A sampling swab 3, offer the upper opening being connected to the lumen on the top of the tube body 1, cooperate in the upper opening
Equipped with a upper cover plug 4, the upper cover plug 4, which is located on described intraluminal one end, is detachably connected the sampling swab 3；On described
There is an accommodating chamber 41, the accommodating chamber 41 is connected by several air holes on the upper cover plug 4 with the lumen in lid plug 4
It is logical, and it is built-in with desiccant 5.
Existing upper cover plug 4 in order to fill in the upper opening and connect the sampling swab 3 can be reserved with it is more
Solid space.
The biological material extraction element empties the solid space in the upper cover plug 4 to form the accommodating chamber 41, then
The desiccant 5 is encapsulated in the accommodating chamber 41 in the upper cover plug 4, the inner space of the upper cover plug 4 is taken full advantage of,
Without increasing by 1 volume of tube body, carried convenient for public security legal medical expert.
The desiccant 5 can quickly absorb the intraluminal steam by the air hole on the upper cover plug 4, keep
It is dry in the lumen, prevent mildew and bacterial growth；The water-absorbent material with humidity indicative function can be used in the desiccant 5,
Such as discoloration silica gel, it is blue before water suction, starts to change colour after water suction, when becoming pink, just no longer play desiccation, root
According to the color of discoloration silica gel, it can judge it whether still effectively before sampling.
The sampling swab 3 is cotton stick swab or flocking swab, and swab head 31 is preferably flat, is easy to wiping and takes
Sample；The sampling swab 3 is suspended in the lumen.
Preferably, the secondary opening of one be connected to the accommodating chamber 41 is offered on the top surface of the upper cover plug 4, the pair is opened
Cooperation is equipped with a secondary lid plug 6 on mouth.
After the desiccant 5 water suction failure, the secondary lid plug 6 can be taken off from the secondary opening, then to institute
The desiccant 5 stated in accommodating chamber 41 is replaced.
The upper cover plug 4 includes interconnecting piece 42 and handle portion 43, and the interconnecting piece 42 is located in the lumen for connecting
The sampling swab 3, the handle portion 43, which is located at outside the lumen, to be used to take for user.
The interconnecting piece 42 connects the sampling swab 3 by inserting mode, with facilitate sampling after separate in the lab
The sampling swab 3 is detected.
Preferably, a partition panel 12 is provided in the lumen, the partition panel 12 does not connect lumen partition mutually
Logical epicoele 11 and cavity of resorption, the upper opening are connected to the epicoele 11, and the sampling swab 3 is arranged；The bottom of the tube body 1
On offer the secondary opening being connected to the cavity of resorption, cooperation is equipped with a lower cover plug 7 in the secondary opening, intracavitary under described to be provided with
Extracting solution 2.
Preferably, the partition panel 12 is structure as a whole with the tube body 1.
It is not to be connected to mutually that a partition panel 12, which is arranged, by lumen partition in the biological material extraction element in the tube body 1
Epicoele 11 and cavity of resorption, for being arranged the sampling swab 3, the cavity of resorption makes the epicoele 11 for the extracting solution 2 to be arranged
It obtains the sampling swab 3 and extracting solution 2 is separately positioned in the different cavity body of same tube body 1, the two is avoided to connect before use
It touches and soaks the swab head 3131 for being broken the sampling swab 33, and realize the desiccant 5 and extracting solution 2 while encapsulating
Purpose in same tube body 1.
When in use, after the upper cover plug 4 being taken out out of described epicoele 11 together with the sampling swab 3, institute is further taken out
The lower cover plug 7 under shed is stated, before wiping sampling point, the sampling swab 3 is first dipped into the extracting solution 2, so that
The swab head 31 draws enough extracting solutions 2；It is dipping the extracting solution 2 and then the lower cover plug 7 is got back into institute
It states under shed；It completes after sampling, then the upper cover plug 4 is got back into the upper opening together with the sampling swab 2.
It is attached between the lower cover plug 7 and tube body 1 by a flexible connecting member 8, the flexible connecting member 8 is being bent
The plug of lower cover plug 7 can be made on the under shed after folding.
As shown in Fig. 2, the flexible connecting member 8 include a lantern ring 81 and both ends respectively with the lantern ring 81 and lower cover plug 7
One connection strap 82 of connection, the lantern ring 81 are sheathed on the outer wall of the lower opening of the tube body 1, and the connection strap 82 can be soft
Property bending fold.The flexible connecting member 8 can prevent the lower cover plug 7 from accidentally losing after taking-up；Preferably, the connection
Item 82 is structure as a whole with the lantern ring 81 and lower cover plug 7 respectively.
The tube body 1 is antistatic part, i.e., the described tube body 1 can be made or on its inner sidewall of antistatic material
Coated with one layer of anti-static coating, to prevent Electrostatic Absorption and destroy the biological material extracted, and the outer surface of the tube body 1
It is upper that there is an at least plane, rolling when preventing from laying flat.Meanwhile the outer surface of the tube body 1 is frosting, passes through oil to facilitate
Property connect on the outer surface of the tube body 1 record case information straight.
Embodiments of the present invention above described embodiment only expresses, the description thereof is more specific and detailed, but can not
Therefore limitations on the scope of the patent of the present invention are interpreted as, as long as skill obtained in the form of equivalent substitutions or equivalent transformations
Art scheme should all be fallen within the scope and spirit of the invention.
Claims (10)
1. a kind of biological material extraction element including the tube body with lumen and is located at the intracorporal sampling swab of the pipe,
The upper opening being connected to the lumen is offered on the top of the tube body, cooperation is equipped with a upper cover plug, institute in the upper opening
It states upper cover plug and is located on described intraluminal one end and be detachably connected the sampling swab；It is characterized in that, in the upper cover plug
With an accommodating chamber, the accommodating chamber is connected to by several air holes of the upper cover beyond the Great Wall with the lumen, and is built-in with dry
Drying prescription.
2. biological material extraction element according to claim 1, which is characterized in that the desiccant is that band humidity instruction is made
Water-absorbent material.
3. biological material extraction element according to claim 1 or 2, which is characterized in that opened on the top surface of the upper cover plug
Equipped with the secondary opening being connected to the accommodating chamber, cooperation is equipped with a secondary lid plug in the secondary opening.
4. biological material extraction element according to claim 1 or 2, which is characterized in that the upper cover plug includes interconnecting piece
And handle portion, the connecting portion is in, for connecting the sampling swab, the handle position is in the lumen in the lumen
It is outer to be used to take for user.
5. biological material extraction element according to claim 1, which is characterized in that be provided with a partition in the lumen
Lumen partition is connected to for mutual disconnected epicoele and cavity of resorption, the upper opening with the epicoele by plate, the partition panel, if
Set the sampling swab；The secondary opening being connected to the cavity of resorption is offered on the bottom of the tube body, is cooperated in the secondary opening
It is intracavitary under described to be provided with extracting solution equipped with a lower cover plug.
6. biological material extraction element according to claim 4, which is characterized in that pass through between the lower cover plug and tube body
One flexible connecting member is attached, and the flexible connecting member can make the lower cover plug plug in the under shed after bending fold
On.
7. biological material extraction element according to claim 5, which is characterized in that the flexible connecting member includes a lantern ring
The connection strap connecting respectively with the lantern ring and lower cover plug with both ends, the lantern ring are sheathed on the lower opening of the tube body
On outer wall, the connection strap can flexible bending folding.
8. biological material extraction element according to claim 1, which is characterized in that the tube body is antistatic part.
9. biological material extraction element according to claim 1, which is characterized in that have extremely on the outer surface of the tube body
A few plane.
10. biological material extraction element according to claim 1, which is characterized in that the outer surface of the tube body is frosted
Face.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811353770.9A CN109439511A (en) | 2018-11-14 | 2018-11-14 | A kind of biological material extraction element |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811353770.9A CN109439511A (en) | 2018-11-14 | 2018-11-14 | A kind of biological material extraction element |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109439511A true CN109439511A (en) | 2019-03-08 |
Family
ID=65553252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811353770.9A Pending CN109439511A (en) | 2018-11-14 | 2018-11-14 | A kind of biological material extraction element |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109439511A (en) |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1405599A1 (en) * | 2002-10-04 | 2004-04-07 | bj-diagnostic GmbH | Device with ventilation openings for taking a sample |
| CN102634448A (en) * | 2012-03-23 | 2012-08-15 | 宁波高新区绿邦科技发展有限公司 | Biological sampling swab |
| CN103033391A (en) * | 2012-12-16 | 2013-04-10 | 广州市刑事科学技术研究所 | Biological detection material collection and storage device |
| CN103389222A (en) * | 2013-08-08 | 2013-11-13 | 苏州麦格华恒贸易有限公司 | Contact biomaterial DNA gathering storage method and device |
| CN106103686A (en) * | 2013-12-04 | 2016-11-09 | 杭州金源生物技术有限公司 | There is the sample cell assembly that improved leakage is taken precautions against |
| CN106190802A (en) * | 2016-07-17 | 2016-12-07 | 佛山市大臻医学检验所有限公司 | Sampling swab for oral cavity |
| CN206026361U (en) * | 2016-07-15 | 2017-03-22 | 武汉康立优医疗发展有限公司 | Integrative device of disposable secretion sampling |
| CN206082572U (en) * | 2016-09-30 | 2017-04-12 | 朱乐文 | Novel rubber head drip tube |
| US20170248498A1 (en) * | 2016-02-25 | 2017-08-31 | Signature Science, Llc | Swab canister equipped with moisture permeable membrane and dessicant |
| CN108455089A (en) * | 2018-04-16 | 2018-08-28 | 深圳市麦瑞科林科技有限公司 | A kind of biological specimen collection and save set |
| CN209481648U (en) * | 2018-11-14 | 2019-10-11 | 广东佛润斯科生物科技有限公司 | A kind of biological material extraction element |
-
2018
- 2018-11-14 CN CN201811353770.9A patent/CN109439511A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1405599A1 (en) * | 2002-10-04 | 2004-04-07 | bj-diagnostic GmbH | Device with ventilation openings for taking a sample |
| CN102634448A (en) * | 2012-03-23 | 2012-08-15 | 宁波高新区绿邦科技发展有限公司 | Biological sampling swab |
| CN103033391A (en) * | 2012-12-16 | 2013-04-10 | 广州市刑事科学技术研究所 | Biological detection material collection and storage device |
| CN103389222A (en) * | 2013-08-08 | 2013-11-13 | 苏州麦格华恒贸易有限公司 | Contact biomaterial DNA gathering storage method and device |
| CN106103686A (en) * | 2013-12-04 | 2016-11-09 | 杭州金源生物技术有限公司 | There is the sample cell assembly that improved leakage is taken precautions against |
| US20170248498A1 (en) * | 2016-02-25 | 2017-08-31 | Signature Science, Llc | Swab canister equipped with moisture permeable membrane and dessicant |
| CN206026361U (en) * | 2016-07-15 | 2017-03-22 | 武汉康立优医疗发展有限公司 | Integrative device of disposable secretion sampling |
| CN106190802A (en) * | 2016-07-17 | 2016-12-07 | 佛山市大臻医学检验所有限公司 | Sampling swab for oral cavity |
| CN206082572U (en) * | 2016-09-30 | 2017-04-12 | 朱乐文 | Novel rubber head drip tube |
| CN108455089A (en) * | 2018-04-16 | 2018-08-28 | 深圳市麦瑞科林科技有限公司 | A kind of biological specimen collection and save set |
| CN209481648U (en) * | 2018-11-14 | 2019-10-11 | 广东佛润斯科生物科技有限公司 | A kind of biological material extraction element |
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