CN109432246A - A kind of Chinese materia medica preparation and preparation method thereof of postpartum uterus rehabilitation - Google Patents
A kind of Chinese materia medica preparation and preparation method thereof of postpartum uterus rehabilitation Download PDFInfo
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Abstract
The invention discloses a kind of Chinese materia medica preparations of postpartum uterus rehabilitation, including following component based on parts by weight of raw materials: 10~20 parts of saururus chinensis, 7~15 parts of Caulis Spatholobi, 2~5 parts of safflower, 2~5 parts of Radix Angelicae Sinensis, 6~20 parts of fructus lycii, 5~15 parts of folium artemisiae argyi, 10~20 parts of motherwort, 2~8 parts of mulberries, 2~8 parts of bird's nest powder, 10~20 parts of Radix Glycyrrhizae.The compatibility that the present invention passes through optimization effective component of chinese medicine, having the Chinese materia medica preparation has tonifying kidney and benefiting sperm, nourishing blood and invigorating qi, promoting blood circulation enriching yin, promotes the effect of benign contraction in uterus, and wide indications, there is significant curative effect to treatment metrorrhagia, lochia non-stop, uterine inertia.The invention also discloses the preparation method of the Chinese materia medica preparation, simple process, strong operability is conducive to large-scale industrial production.
Description
Technical field
The present invention relates to tcm field, in particular to a kind of Chinese materia medica preparation of postpartum uterus rehabilitation.
Background technique
It is a kind of postpartum common disease, frequently-occurring disease that involution of uterus is bad.Involution of uterus refers to the uterus after placenta is given birth to gradually
Restore to the process of non-pregnant state, is mainly shown as that body muscle fibre contracting in palace is multiple and Endometrium regenerates, generally requires 6 weeks or so.With
The raising of cesarean delivery rate, the occurrence of this disease rate gradually increase, while this disease is also to lead to postpartum haemorrhage or late puerperal hemorrhage
One of inducement.Modern medicine believes that, involution of uterus of puerperal is bad for part placenta, fetal membrane residual or placenta attachment area sense
Dye makes part be unable to normal restoration, influences uterine contraction and cause involution of uterus of puerperal bad.Currently, still with Resident placenta membrane,
Intrauterine infection is common.If endometrium and pelvic infection, retroversion, tumour between uterine muscular, multifetation, uterus is fine
Dimension tissue is opposite to be increased, and placenta attachment changes uterine muscular form, structure, and Placental measurement increases, and causes uterus myotility weak,
Inner membrance vessel open section increases, and amount of bleeding is big, the bleeding time is long.Blood stasis of blood in uterine cavity, aggravate uterus contract again it is bad, increase
Retrograde infection.It is clinically mostly treated at present with antibiotic and uterine contraction agent, antibiotic, uterine contraction agent are rapid-action, but action time
It is short, and oxytocin receptor reach saturation after just lose effect, and the treatment method can often bring larger side effect, at the same by
Larger dose oxytocins is used in postpartum, makes uterus tetanic contraction, furthermore oxytocins half-life short, often makes uterus secondary contraction not
It is good, and often there is insufferable uterine contraction pain and refuses to continue to use in puerpera, and ineffective for Abortion person, using model
It encloses and effect is limited.Chinese traditional treatment, most common oral drugs have: yimucao drop preparation, Chanfukang granule etc., but curative effect is simultaneously
It is not fairly obvious.
Summary of the invention
It is an object of the invention in view of the above shortcomings of the prior art, provide a kind of Chinese medicine system of postpartum uterus rehabilitation
Agent, while the preparation method of the Chinese materia medica preparation being provided.
The technical solution used in the present invention is: a kind of Chinese materia medica preparation of postpartum uterus rehabilitation, based on parts by weight of raw materials
Including following component: 10~20 parts of saururus chinensis, 7~15 parts of Caulis Spatholobi, 2~5 parts of safflower, 2~5 parts of Radix Angelicae Sinensis, fructus lycii 6~20
Part, 5~15 parts of folium artemisiae argyi, 10~20 parts of motherwort, 2~8 parts of mulberries, 2~8 parts of bird's nest powder, 10~20 parts of Radix Glycyrrhizae.
As a further improvement of the foregoing solution, including following component based on parts by weight of raw materials: 10~15 parts of saururus chinensis,
7~10 parts of Caulis Spatholobi, 2~4 parts of safflower, 2~4 parts of Radix Angelicae Sinensis, 8~15 parts of fructus lycii, 5~10 parts of folium artemisiae argyi, motherwort 10~15
Part, 5~8 parts of mulberries, 2~5 parts of bird's nest powder, 15~20 parts of Radix Glycyrrhizae.
As a further improvement of the foregoing solution, the particle size of the bird's nest powder is 200~500nm.
Another technical solution adopted by the present invention is: a kind of Chinese materia medica preparation of postpartum uterus as described above rehabilitation
Preparation method, it is characterised in that comprise the technical steps that:
1) 80~90% ethyl alcohol measured saururus chinensis, Caulis Spatholobi, safflower and Radix Angelicae Sinensis with 3 times based on parts by weight of raw materials is molten
Liquid impregnate 1~2h, heating extraction 2h, recycle ethyl alcohol, filtering, concentration filtrate be at 60 DEG C relative density be 1.30~1.35 it is thick
Cream, it is spare；
2) based on parts by weight of raw materials by fructus lycii, folium artemisiae argyi, motherwort, mulberries and Radix Glycyrrhizae co-grinding at 100~200 purposes
Powder adds the water of 4~6 times of amounts to impregnate 1~2h, decocts 2h, filtering, is repeated twice and merging filtrate, heating are concentrated at 60 DEG C
The concentrate that relative density is 1.10~1.20, it is spare；
3) bird's nest powder is mixed with concentrate obtained by thick paste obtained by step 1) and step 2) based on parts by weight of raw materials, through spraying
It is dry, 100~150 mesh fine powders are obtained, granule is made in the rear auxiliary material that is added, and obtains finished product.
The beneficial effects of the present invention are:
The present invention by optimization effective component of chinese medicine compatibility, make the Chinese materia medica preparation have tonifying kidney and benefiting sperm, nourishing blood and invigorating qi,
Invigorate blood circulation enriching yin, promote the effect of benign contraction in uterus, and wide indications, have to treatment metrorrhagia, lochia non-stop, uterine inertia
There is significant curative effect.
Preparation method simple process of the invention, strong operability are conducive to large-scale industrial production.
Specific embodiment
The present invention is specifically described below with reference to embodiment, in order to technical field personnel to of the invention
Understand.It is necessary to it is emphasized that embodiment is only intended to, the present invention will be further described herein, should not be understood as to this
The limitation of invention protection scope, fields person skilled in the art, the non-intrinsically safe that the present invention is made according to foregoing invention content
The modifications and adaptations of property, should still fall within protection scope of the present invention.Mentioned raw materials following simultaneously are unspecified, are
Commercial product；The processing step or preparation method not referred in detail be processing step known to a person skilled in the art or
Preparation method.
Embodiment 1
The Chinese materia medica preparation of a kind of postpartum uterus rehabilitation, including following component based on parts by weight of raw materials: 10 parts of saururus chinensis, chicken
10 parts of blood rattan, 2 parts of safflower, 4 parts of Radix Angelicae Sinensis, 8 parts of fructus lycii, 10 parts of folium artemisiae argyi, 10 parts of motherwort, 8 parts of mulberries, particle size are
15 parts of 5 parts of the bird's nest powder of 200nm, Radix Glycyrrhizae.
Preparation method:
1) 80% ethanol solution that saururus chinensis, Caulis Spatholobi, safflower and Radix Angelicae Sinensis and 3 times are measured is soaked based on parts by weight of raw materials
2h, heating extraction 2h are steeped, recycles ethyl alcohol, filtering, concentration filtrate is the thick paste that relative density is 1.30 at 60 DEG C, spare；
2) based on parts by weight of raw materials by fructus lycii, folium artemisiae argyi, motherwort, mulberries and Radix Glycyrrhizae co-grinding at 200 mesh powders,
Add the water of 4 times of amounts to impregnate 2h, decocts 2h, filtering, is repeated twice and merging filtrate, heating are concentrated into relative density at 60 DEG C and are
1.10 concentrate, it is spare；
3) bird's nest powder is mixed with concentrate obtained by thick paste obtained by step 1) and step 2) based on parts by weight of raw materials, through spraying
It is dry, 150 mesh fine powders are obtained, granule is made in the rear auxiliary material that is added, and obtains 1 finished product of embodiment.
Embodiment 2
The Chinese materia medica preparation of a kind of postpartum uterus rehabilitation, including following component based on parts by weight of raw materials: 15 parts of saururus chinensis, chicken
7 parts of blood rattan, 4 parts of safflower, 2 parts of Radix Angelicae Sinensis, 15 parts of fructus lycii, 5 parts of folium artemisiae argyi, 15 parts of motherwort, 5 parts of mulberries, particle size are
20 parts of 2 parts of the bird's nest powder of 500nm, Radix Glycyrrhizae.
Preparation method:
1) 90% ethanol solution that saururus chinensis, Caulis Spatholobi, safflower and Radix Angelicae Sinensis and 3 times are measured is soaked based on parts by weight of raw materials
1h, heating extraction 2h are steeped, recycles ethyl alcohol, filtering, concentration filtrate is the thick paste that relative density is 1.35 at 60 DEG C, spare；
2) based on parts by weight of raw materials by fructus lycii, folium artemisiae argyi, motherwort, mulberries and Radix Glycyrrhizae co-grinding at 100 mesh powders,
Add the water of 6 times of amounts to impregnate 1h, decocts 2h, filtering, is repeated twice and merging filtrate, heating are concentrated into relative density at 60 DEG C and are
1.20 concentrate, it is spare；
3) bird's nest powder is mixed with concentrate obtained by thick paste obtained by step 1) and step 2) based on parts by weight of raw materials, through spraying
It is dry, 100 mesh fine powders are obtained, granule is made in the rear auxiliary material that is added, and obtains 2 finished product of embodiment.
Embodiment 3
The Chinese materia medica preparation of a kind of postpartum uterus rehabilitation, including following component based on parts by weight of raw materials: 12 parts of saururus chinensis, chicken
8 parts of blood rattan, 3 parts of safflower, 3 parts of Radix Angelicae Sinensis, 10 parts of fructus lycii, 8 parts of folium artemisiae argyi, 12 parts of motherwort, 7 parts of mulberries, particle size are
18 parts of 4 parts of the bird's nest powder of 350nm, Radix Glycyrrhizae.
Preparation method:
1) 85% ethanol solution that saururus chinensis, Caulis Spatholobi, safflower and Radix Angelicae Sinensis and 3 times are measured is soaked based on parts by weight of raw materials
1.5h, heating extraction 2h are steeped, recycles ethyl alcohol, filtering, concentration filtrate is the thick paste that relative density is 1.30 at 60 DEG C, spare；
2) based on parts by weight of raw materials by fructus lycii, folium artemisiae argyi, motherwort, mulberries and Radix Glycyrrhizae co-grinding at 150 mesh powders,
Add the water of 5 times of amounts to impregnate 1.5h, decocts 2h, filtering, is repeated twice and merging filtrate, heating are concentrated into relative density at 60 DEG C and are
1.15 concentrate, it is spare；
3) bird's nest powder is mixed with concentrate obtained by thick paste obtained by step 1) and step 2) based on parts by weight of raw materials, through spraying
It is dry, 150 mesh fine powders are obtained, granule is made in the rear auxiliary material that is added, and obtains 3 finished product of embodiment.
Embodiment 4: case
1, Chen, 24 years old, after patient has given birth to child, lochia was prolonged not clean, lochia muddiness companion's stink, always the hidden pain of abdomen,
There is tenderness feeling, is diagnosed as postpartum subinvolution of uterus.It gives 1 finished product of the embodiment of the present invention to be treated, once a day, often
Readme above-mentioned symptom is substantially reduced after secondary one, 7 days, continues after taking 3 days, and above-mentioned symptom disappears, and reinspection physical recovery is normal,
It has fully recovered.
2, Liao, 29 years old, 28 days after patient's caesarean birth, lochia was substantially clean, and bleeding again, 45 staggering amounts increase at 42 days, quilt
It is diagnosed as postpartum subinvolution of uterus.It gives 2 finished product of the embodiment of the present invention to be treated, twice daily, after one every time, 7 days
Above-mentioned symptom completely disappears, and continues after taking 5 days, and reinspection physical recovery is normal, has fully recovered.
3, Zheng, 33 years old, patient's lochia of cutting open the belly was prolonged not clean, was diagnosed as postpartum subinvolution of uterus.Give this
3 finished product of inventive embodiments is treated, and once a day, above-mentioned symptom completely disappears after two every time, 7 days, continues to take 3 days
Afterwards, reinspection physical recovery is normal, has fully recovered.
Above-described embodiment is the preferred embodiment of the present invention, all with similar technique of the invention and made equivalence changes,
It should belong to protection category of the invention.
Claims (4)
1. a kind of Chinese materia medica preparation of postpartum uterus rehabilitation, it is characterised in that including following component based on parts by weight of raw materials: saururus chinensis
10~20 parts, 7~15 parts of Caulis Spatholobi, 2~5 parts of safflower, 2~5 parts of Radix Angelicae Sinensis, 6~20 parts of fructus lycii, 5~15 parts of folium artemisiae argyi, benefit mother
Careless 10~20 parts, 2~8 parts of mulberries, 2~8 parts of bird's nest powder, 10~20 parts of Radix Glycyrrhizae.
2. a kind of Chinese materia medica preparation of postpartum uterus rehabilitation according to claim 1, it is characterised in that based on parts by weight of raw materials
Including following component: 10~15 parts of saururus chinensis, 7~10 parts of Caulis Spatholobi, 2~4 parts of safflower, 2~4 parts of Radix Angelicae Sinensis, fructus lycii 8~15
Part, 5~10 parts of folium artemisiae argyi, 10~15 parts of motherwort, 5~8 parts of mulberries, 2~5 parts of bird's nest powder, 15~20 parts of Radix Glycyrrhizae.
3. a kind of Chinese materia medica preparation of postpartum uterus rehabilitation according to claim 1 or 2, it is characterised in that: the bird's nest powder
Particle size be 200~500nm.
4. a kind of preparation method of the Chinese materia medica preparation of postpartum uterus as claimed in any one of claims 1 to 3 rehabilitation, feature exist
In comprising the technical steps that:
1) 80~90% ethanol solution that saururus chinensis, Caulis Spatholobi, safflower and Radix Angelicae Sinensis and 3 times are measured is soaked based on parts by weight of raw materials
1~2h, heating extraction 2h to be steeped, ethyl alcohol, filtering are recycled, concentration filtrate is the thick paste that relative density is 1.30~1.35 at 60 DEG C,
It is spare；
2) based on parts by weight of raw materials by fructus lycii, folium artemisiae argyi, motherwort, mulberries and Radix Glycyrrhizae co-grinding at the powder of 100~200 mesh
End adds the water of 4~6 times of amounts to impregnate 1~2h, decocts 2h, filtering, is repeated twice and merging filtrate, heating are concentrated into phase at 60 DEG C
The concentrate for being 1.10~1.20 to density, it is spare；
3) bird's nest powder is mixed based on parts by weight of raw materials with concentrate obtained by thick paste obtained by step 1) and step 2), is done by spraying
It is dry, 100~150 mesh fine powders are obtained, granule is made in the rear auxiliary material that is added, and obtains finished product.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1833682A (en) * | 2006-01-05 | 2006-09-20 | 吉林省力源药业股份有限公司 | Chinese medicinal compsns. for treating postpartum disease |
| CN102397326A (en) * | 2010-09-19 | 2012-04-04 | 谭宝平 | Formula of Chinese angelica-motherwort herb decoction and preparation thereof |
| CN107737330A (en) * | 2017-12-15 | 2018-02-27 | 河南中医药大学 | A kind of Chinese medicinal lotion for treating postpartum pain of body |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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Application publication date: 20190308 |