CN109432167A - A kind of external application physical therapy plaster and preparation method thereof that can be recycled - Google Patents
A kind of external application physical therapy plaster and preparation method thereof that can be recycled Download PDFInfo
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- CN109432167A CN109432167A CN201811501471.5A CN201811501471A CN109432167A CN 109432167 A CN109432167 A CN 109432167A CN 201811501471 A CN201811501471 A CN 201811501471A CN 109432167 A CN109432167 A CN 109432167A
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- 238000000554 physical therapy Methods 0.000 title claims abstract description 66
- 239000011505 plaster Substances 0.000 title claims abstract description 63
- 238000002360 preparation method Methods 0.000 title claims description 19
- 239000000843 powder Substances 0.000 claims abstract description 112
- 239000000919 ceramic Substances 0.000 claims abstract description 73
- 239000000203 mixture Substances 0.000 claims abstract description 59
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 58
- 229910002012 Aerosil® Inorganic materials 0.000 claims abstract description 39
- 239000002245 particle Substances 0.000 claims abstract description 38
- 239000000463 material Substances 0.000 claims abstract description 25
- 239000000284 extract Substances 0.000 claims abstract description 24
- 239000002994 raw material Substances 0.000 claims abstract description 24
- 239000003814 drug Substances 0.000 claims description 42
- 238000002156 mixing Methods 0.000 claims description 38
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- 235000008434 ginseng Nutrition 0.000 claims description 24
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 23
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 23
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- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 23
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- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 23
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- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims description 19
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- 229910002027 silica gel Inorganic materials 0.000 claims description 5
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000008367 deionised water Substances 0.000 claims description 4
- 229910021641 deionized water Inorganic materials 0.000 claims description 4
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- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
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- 241000208688 Eucommia Species 0.000 description 2
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
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- 150000001637 borneol derivatives Chemical class 0.000 description 2
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- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
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- 241000723346 Cinnamomum camphora Species 0.000 description 1
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- 206010061218 Inflammation Diseases 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 235000011203 Origanum Nutrition 0.000 description 1
- 240000000783 Origanum majorana Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 244000203593 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
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- 239000006071 cream Substances 0.000 description 1
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- 230000027950 fever generation Effects 0.000 description 1
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- 230000036541 health Effects 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/44—Applying ionised fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0625—Warming the body, e.g. hyperthermia treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses the physical therapy plaster of a kind of sustainable fever and recycling, can be used for treating and/or relieving pain, improve local microcirculation etc..Physical therapy plaster of the present invention is demoulded by the mixture containing aerosil particles, modified superfine far-infared ceramic powder, plurality of Chinese and its extract, negative ion powder and other materials through high temperature vulcanized.Wherein, the use of modified superfine far-infared ceramic powder may make raw material to be sufficiently mixed dispersion, and various raw materials are combined, and solution disperses the technical issues of bad, fever is uneven, curative effect cannot give full play in the prior art.Physical therapy plaster of the present invention can effectively treat DOMS, improve internal microcirculation, restore physical function, there is therapeutic effect to the illnesss such as shoulder neck disease and joint ache, inflammation and pain can also be effectively eliminated, autoimmunity is improved, and be directed to some women disease such as dysmenorrhea, the proliferation of mammary gland, endocrine disturbance and palace cold etc. similarly to have significant curative effect.
Description
Technical field
The present invention relates to a kind of external application physical therapy plasters that can be recycled more particularly to a kind of treat to ache and improve microcirculation
External application physical therapy plaster and preparation method thereof, sustainable fever and recycling, and temperature pleasant not will cause skin burn.
Background technique
With the fast pace life of modern society, most work crowds lack under busy working environment and social pressures
It is weary it is effective take exercise, it is sedentary, many factors affect people's lives health.Resulting very much " office's synthesis
The illness rate of disease " also significantly rises, and " the comprehensive disease of office " refers to and bend over one's desk working for a long time, lacks shoulder neck disease caused by movement
Some women disease caused by disease, joint disease and sitting etc..Although this disease threatens the life of people not as cancer
Life, but strong influence is really caused to quality of the life.In the case, most of patients can seek some Chinese medicine means to delay
Pain, such as adhesive plaster etc. are solved, the cream in the big dosage form of plaster, that is, Chinese medicine five refers to medicinal substances extract, medicinal material and chemicals
It is sticked made of the matrix and substrate suitable with it for skin, can produce a kind of sheet external application system topically or systemically acted on
Agent.It is unpractical selection for sticking for a long time although plaster has of short duration treatment for specific slight illness, and by
In the form that it is pasted and removes, to patient skin, there is also certain damages.Therefore occur a variety of external applications in the prior art
Physical therapy plaster adds the functions raw materials such as far-infrared powder, negative ion powder, is made into external application physical therapy plaster using Chinese medicine material as physical therapy patch,
Facilitate long-time service, it will not be to skin tape come discomfort when removing.Far-infrared powder in physical therapy plaster can give off than just
The normal more far infrareds of object (infrared emittance is higher), can cause the resonance of the atom and molecule of human body cell, penetrate
Resonant absorption, frictional heat generation forms thermal response between molecule, promotes subcutaneous deep temperature to rise, and make Marjoram Extract, accelerates
Blood circulation promotes tissue to update.Negative ion powder can accelerate the recovery of function of human body comprehensively, so that smooth blood circulation, accelerates
Cell metabolism, and there is analgesic effect.
Physical therapy plaster in the prior art, although containing radiation heat pyrexias such as plurality of Chinese component cooperation far-infrared powders, effect
In affected part, plays and relieve pain, the effect of recovery organization function, but due to the solid powder form of raw material, so that raw material is not
It is easily uniformly dispersed, heat generating spot is uneven, and the combination between raw material and raw material is not close, and drug effect, which is not achieved, sufficiently effectively to be sent out
It waves.It can include suitably a variety of fever class raw materials, so that temperature when sticking is not easily-controllable in addition to drug effect is made to play one's part to the full
System, since temperature control is improper, it may appear that burning sensation is sticked, is used for a long time and equally will cause certain damage to patient skin,
If excessively controlled temperature, while it will cause being unable to give full play for drug effect, drug effect duration is bad.
Summary of the invention
For this purpose, the present invention provides a kind of external application physical therapy plaster that can be recycled, by selecting the Chinese medicine of various reasonable former
Specific modified superfine far-infared ceramic powder is added in material, cooperates negative ion powder, obtained external application physical therapy plaster can effective therapic acid
Bitterly, improve internal microcirculation, restore physical function.By modified obtained ultra-fine far-infared ceramic powder, raw material is filled
Divide mixing dispersion, and various raw materials are combined, solution prior art dispersion is bad, uneven, curative effect of generating heat cannot fill
The technical issues of distribution is waved.Another technical solution of the invention provides a kind of external application physical therapy plaster that can be recycled, further
The burning sensation for sticking appearance is reduced, and by energy storage extension by keeping the temperature the thermal storage performance of temperature control layer containing heat preservation temperature control layer
Medicine raw material drug effect action time, reach the technical effect of effective continued treatment pain.
Therefore, the present invention provides a kind of external application physical therapy plaster that can be recycled, especially a kind for the treatment of is ached and is improved micro-
The external application physical therapy plaster and preparation method of circulation.It is realized by using following technical scheme:
A kind of external application physical therapy plaster that can be recycled is formulated according to parts by weight as 20-40 parts of Radix Angelicae Sinensis, 1-10 parts of ginseng, safflower
10-30 parts, 1-20 parts of peppermint, 1-10 parts of Radix Angelicae Pubescentis, 5-15 parts of Cortex Eucommiae, 1-10 parts of folium artemisiae argyi, 1-10 parts of cortex periplocae, 5-15 parts of borneol,
10-35 parts of gaultherolin, 5-20 parts of sorbic acid, 10-30 parts of modified superfine far-infared ceramic powder, 10-25 parts of negative ion powder, silicon
20-90 parts of glue particle.
Preferred external application physical therapy plaster of the invention is formulated according to parts by weight as 25-35 parts of Radix Angelicae Sinensis, 2-10 parts of ginseng, red
Flower 11-25 parts, 7-15 parts of peppermint, 3-5 parts of Radix Angelicae Pubescentis, 5-11 parts of Cortex Eucommiae, 2-8 parts of folium artemisiae argyi, 3-5 parts of cortex periplocae, 6-12 parts of borneol, water
15-33 parts of poplar acid methyl esters, 8-17 parts of sorbic acid, 13-26 parts of modified superfine far-infared ceramic powder, 14-23 parts of negative ion powder, silica gel
45-70 parts of particle.
Preferred external application physical therapy plaster of the invention is formulated according to weight fraction as 28 parts of Radix Angelicae Sinensis, 5 parts of ginseng, safflower 14
Part, 8 parts of peppermint, 3 parts of Radix Angelicae Pubescentis, 7 parts of Cortex Eucommiae, 6 parts of folium artemisiae argyi, 3 parts of cortex periplocae, 11 parts of borneol, 25 parts of gaultherolin, sorbic acid 17
Part, 21 parts of modified superfine far-infared ceramic powder, 14 parts of negative ion powder, 50 parts of aerosil particles.
Preferred external application physical therapy plaster of the invention is formulated according to weight fraction as 31 parts of Radix Angelicae Sinensis, 7 parts of ginseng, safflower 17
Part, 11 parts of peppermint, 5 parts of Radix Angelicae Pubescentis, 5 parts of Cortex Eucommiae, 4 parts of folium artemisiae argyi, 5 parts of cortex periplocae, 7 parts of borneol, 18 parts of gaultherolin, sorbic acid 12
Part, 20 parts of modified superfine far-infared ceramic powder, 17 parts of negative ion powder, 65 parts of aerosil particles.
The present invention also provides a kind of external application physical therapy plaster that can be recycled, containing Chinese medicine material extract and substrate,
Middle Chinese medicine material extract is by according to parts by weight are as follows: 20-40 parts of Radix Angelicae Sinensis, 1-10 parts of ginseng, 10-30 parts of safflower, peppermint 1-20
The mixing Chinese medicine material extraction of part, 1-10 parts of Radix Angelicae Pubescentis, 5-15 parts of Cortex Eucommiae, 1-10 parts of folium artemisiae argyi, 1-10 parts of cortex periplocae, 5-15 parts of borneol
And it is concentrated and dried, also, the parts by weight of substrate are relative to Chinese medicine material, are gaultherolin 1-6 parts, sorbic acid 2-5
Part, 1-6 parts of modified superfine far-infared ceramic powder, 2-5 parts of negative ion powder, 3-25 parts of aerosil particles.
A kind of preferred external application physical therapy plaster that can be recycled of the invention, containing Chinese medicine material extract and substrate,
Middle Chinese medicine material extract is by according to parts by weight are as follows: 25-35 parts of Radix Angelicae Sinensis, 2-7 parts of ginseng, 11-25 parts of safflower, peppermint 7-15
Part, 3-5 parts of Radix Angelicae Pubescentis, 5-11 parts of Cortex Eucommiae, 2-8 parts of folium artemisiae argyi, 3-5 parts of cortex periplocae, 6-12 parts of borneol mixing Chinese medicine material extract simultaneously
Be concentrated and dried, also, the parts by weight of substrate are relative to Chinese medicine material, be gaultherolin 2-4 parts, 3-4 parts of sorbic acid,
2-5 parts of modified superfine far-infared ceramic powder, 2-3 parts of negative ion powder, 5-15 parts of aerosil particles.
Modified superfine far-infared ceramic powder in physical therapy plaster of the present invention, it is modified to far-infared ceramic powder using coupling agent, to
Coupling agent is added in far-infared ceramic powder, is sufficiently stirred, filtration drying, then air-flow crushing, it is far red to finally obtain modified superfine
Outer ceramic powder, by changing the surface property of far-infared ceramic powder, allow itself and Chinese medicine material is fully dispersed mixes, improve
Combination between raw material has the function that the uniform raising medicament validity of heat generating spot.It is preferred that modified superfine far infrared
The average grain diameter d of ceramic powder50For 200-2000nm.
The coupling agent is selected from silane coupling agent or titanate coupling agent, preferably silane coupling agent, further preferably
KH550, KH560, KH570 or KH792.The dosage of coupling agent is 0.1~5% parts by weight of far-infared ceramic powder, preferably remote red
1% parts by weight of outer ceramic powder.
External application physical therapy plaster of the invention, using following preparation method:
(1) according to composition of raw materials measurement aerosil particles, the heating melting at 185-230 DEG C, for use;
(2) coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum drying,
Using air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
(3) silicon of step (1) melting is added in the modified superfine far-infared ceramic powder and negative ion powder of the step of taking formula ratio (2)
It is stirred in glue particle, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes;
(4) by the Radix Angelicae Sinensis in formula, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae, borneol, gaultherolin, mountain
Pears acid is stirred, and is added in the mixture of step (3), and stirring 40 minutes, mixing speed 250r/min are continued;
(5) vulcanizing agent is added in the mixture for obtaining step (4), injects in mold, high temperature vulcanized to demould up to external application physical therapy plaster,
Wherein high temperature vulcanized temperature is 150-180 DEG C.
In another embodiment, preparation method of the invention includes:
(1) aerosil particles are measured according to composition of raw materials, the heating melting at 185-230 DEG C injects desulfurization in mold and obtains silica gel
Particle substrate;
(2) coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum drying,
Using air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
(3) the modified superfine far-infared ceramic powder of the step of taking formula ratio (2), negative ion powder, gaultherolin, sorbic acid stirring
It is mixed, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes;
(4) Radix Angelicae Sinensis of formula ratio, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are mixed 40 points
Clock, mixing speed 250r/min;
(5) mixture for obtaining step (3) and step (4) mixes, and the painting of gained mixture is pressed on aerosil particles substrate, obtains
External application physical therapy plaster.
In another embodiment, preparation method of the invention includes:
(1) Radix Angelicae Sinensis, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are weighed according to formula ratio, use is ultra-fine
Pulverizer carries out co-grinding, reaches 95% or more sporoderm-broken rate;
(2) deionized water is added in the powder obtained to step (1) and carries out infiltration 30 minutes;
Chinese medicine liquid extraction is carried out to the mixture of step (2) at (3) 100 DEG C, extracts 3 times repeatedly, obtains Chinese medicine extract, to
With;
(4) coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum drying,
Using air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
The modified superfine far-infared ceramic powder that (5) obtains (4) the step of Chinese medicine extract and formula ratio that step (3) obtains,
Negative ion powder, gaultherolin, sorbic acid are stirred stirring, are kept for 200 DEG C of temperature, mixing speed 200r/min stirs 40 points
Clock;
(6) aerosil particles, the heating melting at 185-230 DEG C are measured according to composition of raw materials, the mixture that step (5) are added adds
Enter vulcanizing agent, inject mold, high temperature vulcanized demoulding obtains external application physical therapy plaster, and curing temperature therein is 160 DEG C.
Further, external application physical therapy plaster of the invention also contains heat preservation temperature control layer, by including aerosil 10-25
Part, 5-20 parts of diatomite and 5-20 parts of polyvinyl alcohol glue;It is preferred that 15-24 parts of aerosil, 10-18 parts of diatomite and poly-
The mixture that 10-15 parts of vinyl alcohol glue is prepared.
Slow down medicament using its structural void degree by addition aerosil and diatomite and directly act on skin
The side effect of skin reconciles Chinese drugs agentia to the burning sensation of skin, controls temperature, obtains the comfortable sense that sticks, and pass through energy storage function
Effect mitigates medicament drug effect, extends pharmacy effect.
Further physical therapy plaster of the present invention the preparation method comprises the following steps:
(1) according to composition of raw materials measurement aerosil particles, the heating melting at 185-230 DEG C, for use;
(2) coupling agent is added into ultra-fine far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum
It is dry, using air-flow crushing, obtain average grain diameter d50For the modified superfine far-infared ceramic powder of 200-2000nm;
(3) molten silicon of step (2) is added in the modified superfine far-infared ceramic powder and negative ion powder of the step of taking formula ratio (2)
It is stirred in glue particle, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes, obtains mixture a;
(4) aerosil, diatomite and polyvinyl alcohol glue of formula ratio are taken, it is mixed with the speed of mixing speed 200r/min
Stirring 20 minutes is closed, mixture b is obtained;
(5) by the Radix Angelicae Sinensis of formula ratio, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae, borneol, gaultherolin and
Sorbic acid is stirred, and is added in the mixture a of step (3), and stirring 40 minutes, mixing speed 250r/min are continued;
(6) the mixture b of step (4) is added in the mixture of step (5), stirs 30 points with mixing speed 250r/min
Clock;
(7) mixture of step (6) is added in sulfide injection mold, it is high temperature vulcanized to demould up to external application physical therapy plaster, high temperature
Curing temperature is 150-180 DEG C.
In another embodiment, preparation method of the invention includes:
(1) Radix Angelicae Sinensis, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are weighed according to formula ratio, use is ultra-fine
Pulverizer carries out co-grinding, reaches 95% or more sporoderm-broken rate;
(2) deionized water is added in the powder obtained to step (1) and carries out infiltration 30 minutes;
Chinese medicine liquid extraction is carried out to the mixture that step (2) obtains at (3) 100 DEG C, extracts 3 times repeatedly, obtains Chinese medicine extract,
For use;
(4) coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum drying,
Using air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm, for use;
(5) aerosil, diatomite and polyvinyl alcohol glue of formula ratio are taken, it is mixed with the speed of mixing speed 200r/min
Stirring 20 minutes is closed, mixture is obtained;
(6) by the Chinese medicine extract of step (3), step (5) mixture and formula ratio the step of (4) modified superfine far infrared
Ceramic powder, negative ion powder, gaultherolin, sorbic acid are stirred stirring, are kept for 200 DEG C of temperature, mixing speed 200r/min
Stirring 40 minutes;
(7) aerosil particles, the heating melting at 185-230 DEG C are measured according to composition of raw materials, the mixture that step (6) are added adds
Enter sulfide, inject mold, high temperature vulcanized demoulding obtains external application physical therapy plaster;Wherein high temperature vulcanized temperature is 180 DEG C
In another embodiment, preparation method of the invention includes:
(1) aerosil particles are measured according to composition of raw materials, the heating melting at 185-230 DEG C injects desulfurization in mold and obtains silica gel
Particle substrate;
(2) coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, vacuum drying,
Using air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
(3) the modified superfine far-infared ceramic powder of the step of taking formula ratio (2), negative ion powder, gaultherolin, sorbic acid stirring
It is mixed, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes, obtains mixture a;
(4) aerosil, diatomite and polyvinyl alcohol glue of formula ratio are taken, it is mixed with the speed of mixing speed 200r/min
Stirring 20 minutes is closed, mixture b is obtained;
(5) by the Radix Angelicae Sinensis of formula ratio, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae, borneol, 40 points are mixed
Clock, mixing speed 250r/min obtain mixture c;
(6) mixture c obtained in mixture a obtained in step (3) and step (5) is mixed, with mixing speed 250r/
Min is stirred 30 minutes;
(7) painting of mixture obtained in step (6) is pressed on aerosil particles substrate;
(8) mixture b painting will be obtained in step (4) to be pressed on the substrate that step (7) obtains, and obtains external application physical therapy plaster.
Compared with prior art, the modified superfine far-infared ceramic powder that the present invention uses is made by specific method of modifying
It obtains far-infared ceramic powder and has excellent surface property, can have good dispersibility with other components, existing skill will not be generated
Physical therapy plaster fever in art is uneven, the incomplete technical problem of drug action;In addition present invention adds silica gas is molten
Glue and diatomite reach control temperature using its textural porosity, alleviate the burn feeling that drug effect continuingly acts on skin generation,
And the time that drug effect plays is extended by energy storage effect, while in patient in use, can make according to pain degree appropriate adjustment
With the time, can also repeatedly be repeatedly circulated, it is flexible and convenient to use.
Physical therapy plaster of the invention, which has close to the comfortable of body temperature, sticks impression, while guaranteeing that drug effect can give full play to, and has
Effect treatment pain, improves body microcirculation, restores the effect of body function.
Specific embodiment
The present invention is further explained combined with specific embodiments below.
Embodiment 1
The preparation for the external application physical therapy plaster that the present invention can be recycled:
(1) aerosil particles for taking 500 grams are put into electronic thermostatic reaction pot after being heated to molten condition at 200 DEG C and keep molten
Melt and stand-by;
(2) 300 grams of far-infared ceramic powder are taken, 3 grams of coupling agent KH550 are added thereto, is uniformly mixed, in reaction pot at 250 DEG C
Middle stirring 30 minutes, takes out, and is dried under vacuum 150 minutes after washing filtering with vacuum oven, cooling after taking-up, is placed in city
It sells and carries out air-flow crushing in airslide disintegrating mill, obtain average grain diameter d50For the modified superfine far-infared ceramic powder of 200-2000nm
267.7 gram;
(3) 210 grams of modified superfine far-infared ceramic powders obtained in step (2) and 140 grams of negative ion powders are taken, are added step (1)
Melting aerosil particles in constant temperature stirring, keep 200 DEG C of temperature, mixing speed 200r/min, stir 40 minutes;
(4) by 280 grams of Radix Angelicae Sinensis, 50 grams of ginsengs, 140 grams of safflowers, 80 grams of peppermints, 30 grams of Radix Angelicae Pubescentis, 70 grams of Cortex Eucommiaes, 60 grams of folium artemisiae argyis, 30
Gram cortex periplocae, 110 grams of borneols, 250 grams of gaultherolins, 170 Keshan pears acid-mixeds are closed, and are added in the mixture of step (3), are protected
It holds 200 DEG C of temperature and continues stirring 40 minutes, mixing speed 250r/min;
(5) appropriate vulcanizing agent is added after taking out the mixture of step (4) and injects mold, the high temperature vulcanized demoulding at 150 DEG C
Up to external application physical therapy plaster.About 10-110 external application physical therapy plasters can be made according to mold size and actual use dimensional thickness, preferably
20-40.
Embodiment 2
External application physical therapy plaster of the invention is formulated according to weight fraction as 310 grams of Radix Angelicae Sinensis, 7 grams of ginseng, 170 grams of safflower, peppermint 110
Gram, 50 grams of Radix Angelicae Pubescentis, 50 grams of Cortex Eucommiae, 40 grams of folium artemisiae argyi, 50 grams of cortex periplocae, 70 grams of borneol, 180 grams of gaultherolin, sorbic acid 120
Gram, 170 grams of negative ion powder, 650 grams of aerosil particles.280 grams of far-infrared ceramic powder raw material, coupling agent used is KH792, and dosage is
1.4 grams, 269.1 grams of far infrared ultrafine ceramic powder are obtained, takes 200 grams of uses.Preparation method and reaction condition are the same as embodiment 1.Root
About 10-112 external application physical therapy plasters can be made according to mold size and actual use dimensional thickness, preferably 20-40 opens.
Embodiment 3
With the same component of embodiment 1 and formula, the preparation method is as follows:
(1) Radix Angelicae Sinensis, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are weighed according to formula ratio, use is ultra-fine
Pulverizer carries out co-grinding, reaches 95% or more sporoderm-broken rate;
(2) 1200ml deionized water is added in the powder obtained to step (1) and carries out infiltration 30 minutes;
Chinese medicine liquid extraction is carried out to mixture to step (2) at (3) 100 DEG C, is mentioned using conventional medium-sized traditional Chinese medicine extraction system
It takes, extracts 3 times repeatedly, merging obtains Chinese medicine extract, is further concentrated and dried, obtains 63.2 grams of rough materials, for use;
(4) 180 grams of far-infared ceramic powder are taken, 3.2 grams of coupling agent KH560 are added thereto, is uniformly mixed, is being reacted at 250 DEG C
It stirs 30 minutes, takes out in pot, be dried under vacuum 150 minutes after washing filtering with vacuum oven, it is cooling after taking-up, it is placed in
Air-flow crushing is carried out in commercially available airslide disintegrating mill, obtains average grain diameter d50For the modified superfine far-infared ceramic powder of 200-2000nm
168.3 gram;
(5) take the traditional Chinese medicine extraction of step (3) that the modified superfine far-infared ceramic powder of rough material and 50 grams of steps (4), 30 grams is concentrated
Negative ion powder, 40 grams of gaultherolins, 35 grams of sorbic acids are stirred stirring, are kept for 200 DEG C of temperature, mixing speed 200r/min
Stirring 40 minutes;
(6) 120 grams of aerosil particles are taken, the heating melting at 220 DEG C is added the mixture of step (5), injects mould after mixing
Tool is added the high temperature vulcanized demoulding of appropriate vulcanizing agent and obtains external application physical therapy plaster;Curing temperature is 178 DEG C.According to mold size and reality
About 3-15 external application physical therapy plasters can be made using dimensional thickness in border, and preferably 2.
Embodiment 4
(1) 500 grams of aerosil particles are taken, heating melting in electronic thermostatic reaction pot is put at 200 DEG C, injects in mold and sulphur is added
Agent vulcanization demoulding obtains the thin substrate of aerosil particles;About 10-110 can be made according to mold size and actual use dimensional thickness
Substrate, preferably 20-40.
(2) 300 grams of far-infrared ceramic powder raw material are taken, coupling agent KH550 is added thereto, is uniformly mixed, anti-at 250 DEG C
It answers in pot and stirs 30 minutes, take out, be dried under vacuum 150 minutes after washing filtering with vacuum oven, it is cooling after taking-up, it sets
Air-flow crushing is carried out in commercially available airslide disintegrating mill, obtains average grain diameter d50For the modified superfine far-infrared ceramic of 200-2000nm
265.3 grams of powder;
(3) 210 grams of modified superfine far-infared ceramic powder, 140 grams of negative ion powders, 250 grams of gaultherolins, 170 Keshan pears are taken
Acid is stirred stirring, is kept for 200 DEG C of temperature, and mixing speed 200r/min is stirred 40 minutes, obtains mixture a;
(4) 200 grams of aerosils, 150 grams of diatomite and 130 grams of polyvinyl alcohol glues are taken, are placed in reaction pot, 200
It is mixed 20 minutes at DEG C with the speed of mixing speed 200r/min, obtains molten mixture b;
(5) by 280 grams of Radix Angelicae Sinensis, 50 grams of ginsengs, 140 grams of safflowers, 80 grams of peppermints, 30 grams of Radix Angelicae Pubescentis, 70 grams of Cortex Eucommiaes, 60 grams of folium artemisiae argyis, 30
Gram cortex periplocae, 110 grams of borneols are mixed 40 minutes at 200 DEG C, and mixing speed 250r/min obtains mixture c;
(6) mixture c obtained in mixture a obtained in step (3) and step (5) is mixed, is kept 200 at 200 DEG C,
With mixing speed 250r/min stirring 30 minutes;
(7) mixture that step (6) obtains is divided into 10-110 parts, is preferably divided into 20-40 parts, painting is pressed onto aerosil particles substrate
On;
(8) mixture b obtained in step (4) is divided into 10-110 parts, is preferably divided into 20-40 parts, painting is pressed in step (7) and obtains
Substrate on, obtain external application physical therapy plaster.
Comparative example 1
The formula and embodiment 1 of physical therapy plaster are identical, replace modified superfine far infrared therein with common commercially available far-infared ceramic powder
Ceramic powder, the preparation method is the same as that of Example 1
Comparative example 2
The formula of physical therapy plaster are as follows: 5 parts of pepper, 4 parts of peppermint, 3 parts of camphor, 13 parts of heat sensitizer, 11 parts of macrobiosis sand powder, 3 parts of borneol, remote
15 parts of infrared ceramic powder, 10 parts of negative ion powder.It is specific that the preparation method is the same as that of Example 1
Comparative example 3
Choose commercially available far-infrared physiotherapy patch.
It detects the treatment pain condition of each embodiment and comparative example, stick temperature and efficacy time.
Treat pain effective evaluation: 1 disappears for original symptom, and functional recovery is normal;2 disappear substantially for original symptom, ache
Pain is alleviated;3 are mitigated for original symptom;4 absolutely not improve for symptom.
70 patients with shoulder aches are taken to test, random test embodiment 1-4 and comparative example 1-3 are sticked outer
With two courses for the treatment of of physical therapy plaster, one the course for the treatment of seven days, the results are shown in Table 1:
Table 1
As it can be seen that external application physical therapy plaster of the present invention has reached treatment pain by the selection and cooperation of component formula, improve that body is micro- to follow
Ring, so that the technical effect of functional recovery.
Temperature and efficacy time evaluation and test are sticked, the results are shown in Table 2:
Table 2
The experimental results showed that, external application physical therapy plaster of the present invention, which obviously has, comfortably sticks temperature above, not will cause the burning of skin
It burns and feels, and keep lasting efficacy time simultaneously.
Physical therapy plaster of the present invention can effectively treat the illnesss such as various aching pain of muscles, shoulder neck disease and joint ache, can also be effective
It diminishes inflammation and pain, improves autoimmunity, and it is disorderly to be directed to some women disease such as dysmenorrhea, the proliferation of mammary gland, endocrine
Random and palace cold etc. similarly has significant curative effect.
Although a specific embodiment of the invention is hereinbefore described, it is to be understood that above-described embodiment is specific
Example is not considered as limiting the invention, and those skilled in the art are not departing from the principle of the present invention and objective
In the case where, above-described embodiment can be modified and be changed within the scope of the invention.
Claims (10)
1. a kind of external application physical therapy plaster that can be recycled, which is characterized in that containing Chinese medicine material ingredient and substrate, wherein Chinese medicine is pressed
According to parts by weight are as follows: 20-40 parts of Radix Angelicae Sinensis, 1-10 parts of ginseng, 10-30 parts of safflower, 1-20 parts of peppermint, 1-10 parts of Radix Angelicae Pubescentis, Cortex Eucommiae 5-
15 parts, 1-10 parts of folium artemisiae argyi, 1-10 parts of cortex periplocae, 5-15 parts of borneol;Also, substrate is according to parts by weight are as follows: gaultherolin 10-
40 parts, 5-30 parts of sorbic acid, 10-40 parts of modified superfine far-infared ceramic powder, 10-30 parts of negative ion powder, aerosil particles 20-90
Part.
2. a kind of external application physical therapy plaster that can be recycled according to claim 1, which is characterized in that containing Chinese medicine material ingredient and
Substrate, it is therein it is important according to parts by weight are as follows: 25-35 parts of Radix Angelicae Sinensis, 2-7 parts of ginseng, 11-25 parts of safflower, 7-15 parts of peppermint, solely
3-5 parts, 5-11 parts of Cortex Eucommiae, 2-8 parts of folium artemisiae argyi, 3-5 parts of cortex periplocae, 6-12 parts of borneol living;Also, substrate is according to parts by weight are as follows:
15-33 parts of gaultherolin, 8-17 parts of sorbic acid, 13-26 parts of modified superfine far-infared ceramic powder, 14-23 parts of negative ion powder, silicon
45-70 parts of glue particle.
3. a kind of external application physical therapy plaster that can be recycled, which is characterized in that containing Chinese medicine material extract and substrate, wherein Chinese medicine
Raw extract is by according to parts by weight are as follows: 20-40 parts of Radix Angelicae Sinensis, 1-10 parts of ginseng, 10-30 parts of safflower, 1-20 parts of peppermint, Radix Angelicae Pubescentis
1-10 parts, 5-15 parts of Cortex Eucommiae, 1-10 parts of folium artemisiae argyi, 1-10 parts of cortex periplocae, 5-15 parts of borneol mixing Chinese medicine material extract and be concentrated
Drying forms, also, the parts by weight of substrate are gaultherolin 1-6 parts, 2-5 parts of sorbic acid, are modified relative to Chinese medicine material
Ultra-fine far-infared ceramic powder 1-6 parts, 2-5 parts of negative ion powder, 3-25 parts of aerosil particles.
4. a kind of external application physical therapy plaster that can be recycled of claim 3, which is characterized in that contain Chinese medicine material extract and base
Material, wherein Chinese medicine material extract is by according to parts by weight are as follows: 25-35 parts of Radix Angelicae Sinensis, 2-7 parts of ginseng, 11-25 parts of safflower, peppermint
7-15 parts, 3-5 parts of Radix Angelicae Pubescentis, 5-11 parts of Cortex Eucommiae, 2-8 parts of folium artemisiae argyi, 3-5 parts of cortex periplocae, 6-12 parts of borneol mixing Chinese medicine material mention
It takes and is concentrated and dried, also, the parts by weight of substrate are relative to Chinese medicine material, are gaultherolin 2-4 parts, sorbic acid 3-
4 parts, 2-5 parts of modified superfine far-infared ceramic powder, 2-3 parts of negative ion powder, 5-15 parts of aerosil particles.
5. external application physical therapy plaster according to claim 1-4, which is characterized in that the modified superfine far-infrared ceramic
Powder is that coupling agent is added into far-infared ceramic powder, is sufficiently stirred that filtration drying, then air-flow crushing, it is remote to obtain modified superfine
Infrared ceramic powder;It is preferred that the average grain diameter d of the modified superfine far-infared ceramic powder50For 200-2000nm;It is preferred that described
Coupling agent be selected from silane coupling agent or titanate coupling agent.
6. external application physical therapy plaster according to claim 1-4, which is characterized in that the coupling agent be KH550,
KH560, KH570 or KH792, dosage are 0.1~5% parts by weight of far-infared ceramic powder, preferably 1% parts by weight.
7. external application physical therapy plaster according to claim 1 or 2, which is characterized in that further comprise aerosil 10-
25 parts, 5-20 parts of diatomite and 5-20 parts of polyvinyl alcohol glue;It is preferred that 15-24 parts of aerosil, 10-18 parts of diatomite and
10-15 parts of polyvinyl alcohol glue.
8. a kind of preparation method for the external application physical therapy plaster that can be recycled, which is characterized in that -2 or 5-6 appoints according to claim 1
The formula of one external application physical therapy plaster, prepares in accordance with the following methods:
According to composition of raw materials measurement aerosil particles, the heating melting at 185-230 DEG C, for use;
Coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, and vacuum drying is adopted
With air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
The modified superfine far-infared ceramic powder and negative ion powder of the step of taking formula ratio (2) are added in melting aerosil particles and stir,
Kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes;
By Radix Angelicae Sinensis, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae, borneol, gaultherolin, the sorb in formula
Acid is stirred, and is added in the mixture of step (3), and stirring 40 minutes, mixing speed 250r/min are continued;
Vulcanizing agent is added in the mixture that step (4) is obtained, and injects mold, high temperature vulcanized to demould up to physical therapy plaster product, wherein
High temperature vulcanized temperature is 150-180 DEG C;
Alternatively, preparing in accordance with the following methods:
Aerosil particles are measured according to composition of raw materials, and the heating melting at 185-230 DEG C injects in mold that obtain silica gel micro- for desulfurization
Grain substrate;
Coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, and vacuum drying is adopted
With air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
The modified superfine far-infared ceramic powder of the step of taking formula ratio (2), negative ion powder, gaultherolin, sorbic acid stirring are mixed
Stirring is closed, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes;
The Radix Angelicae Sinensis of formula ratio, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are mixed 40 minutes,
Mixing speed 250r/min;
The mixture that step (3) and step (4) are obtained mixes, and the painting of gained mixture is pressed on aerosil particles substrate, obtains outer
Use physical therapy plaster.
9. a kind of preparation method for the external application physical therapy plaster that can be recycled, which is characterized in that appointed according to claim 3-4 or 5-6
The formula of one external application physical therapy plaster is prepared according to following preparation method:
Radix Angelicae Sinensis, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae and borneol are weighed according to formula ratio, using superfine powder
Broken machine carries out co-grinding, reaches 95% or more sporoderm-broken rate;
Deionized water is added into obtained powder and carries out infiltration 30 minutes;
Chinese medicine liquid extraction is carried out to the mixture that step (2) obtains at 100 DEG C, extracts 3 times repeatedly, obtains Chinese medicine extract, to
With;
Coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, and vacuum drying is adopted
With air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
By modified superfine far-infared ceramic powder, negative ion powder, the water of (4) the step of the Chinese medicine extract and formula ratio of step (3)
Poplar acid methyl esters, sorbic acid are stirred stirring, are kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes;
Aerosil particles are measured according to composition of raw materials, the mixture of step (5) is added in the heating melting at 185-230 DEG C, is added
Vulcanizing agent injects mold, and high temperature vulcanized demoulding obtains external application physical therapy plaster, wherein high temperature vulcanized temperature is 150-180 DEG C.
10. a kind of preparation method for the external application physical therapy plaster that can be recycled, which is characterized in that external application reason according to claim 7
The formula for treating patch, prepares in accordance with the following methods:
Aerosil particles, the heating melting at 185-230 DEG C are measured according to composition of raw materials, injection mold cure demoulds to obtain silica gel
Particle substrate;
Coupling agent is added into far-infared ceramic powder, is uniformly mixed, 250 DEG C are stirred 30 minutes, washing filtering, and vacuum drying is adopted
With air-flow crushing, average grain diameter d is obtained50For the modified superfine far-infared ceramic powder of 200-2000nm;
The modified superfine far-infared ceramic powder of the step of taking formula ratio (2), negative ion powder, gaultherolin, sorbic acid stirring are mixed
Stirring is closed, is kept for 200 DEG C of temperature, mixing speed 200r/min is stirred 40 minutes, obtains mixture a;
The aerosil, diatomite and polyvinyl alcohol glue of formula ratio are taken, is mixed with the speed of mixing speed 200r/min
Stirring 20 minutes, obtains mixture b;
By the Radix Angelicae Sinensis of formula ratio, ginseng, safflower, peppermint, Radix Angelicae Pubescentis, Cortex Eucommiae, folium artemisiae argyi, cortex periplocae, borneol, it is mixed 40 minutes,
Mixing speed 250r/min obtains mixture c;
The mixing of mixture c obtained in mixture a and step (5) will be obtained in step (3), with mixing speed 250r/min stirring
30 minutes;
The painting of mixture obtained in step (6) is pressed on aerosil particles substrate;
The mixture b painting of step (4) is pressed on the substrate that step (7) obtains, external application physical therapy plaster is obtained.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110433237A (en) * | 2019-09-18 | 2019-11-12 | 郑州伊品医药科技有限公司 | A kind of cream peace health-care patch and preparation method thereof |
CN111568632A (en) * | 2020-05-22 | 2020-08-25 | 天津缔道生物科技股份有限公司 | Preparation method of intelligent constant-temperature physiotherapy patch |
CN113577569A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Method for preparing far infrared physiotherapy plaster by irradiation foaming |
CN113577043A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Preparation process of far infrared physiotherapy plaster |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004203849A (en) * | 2002-12-20 | 2004-07-22 | Hasegawa Yuichi | Fiber and textile product produced by using medicinal herb |
CN101058663A (en) * | 2007-05-15 | 2007-10-24 | 中南大学 | Far infrared health care macromolecule composite material |
CN105943238A (en) * | 2016-06-15 | 2016-09-21 | 马南行 | Hot compress sticker for improving microcirculation and preparation method thereof |
CN108478932A (en) * | 2018-03-29 | 2018-09-04 | 缔道(天津)生物科技有限责任公司 | Multifunction infrared mild moxibustion physiotherapy note product and preparation method thereof |
-
2018
- 2018-12-10 CN CN201811501471.5A patent/CN109432167A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004203849A (en) * | 2002-12-20 | 2004-07-22 | Hasegawa Yuichi | Fiber and textile product produced by using medicinal herb |
CN101058663A (en) * | 2007-05-15 | 2007-10-24 | 中南大学 | Far infrared health care macromolecule composite material |
CN105943238A (en) * | 2016-06-15 | 2016-09-21 | 马南行 | Hot compress sticker for improving microcirculation and preparation method thereof |
CN108478932A (en) * | 2018-03-29 | 2018-09-04 | 缔道(天津)生物科技有限责任公司 | Multifunction infrared mild moxibustion physiotherapy note product and preparation method thereof |
Non-Patent Citations (2)
Title |
---|
孙宝勇 等: "纳米远红外陶瓷粉填充UHMWPE复合材料的性能研究", 《塑料工业》 * |
弓太生 等: "远红外粉体表面处理的工艺优化", 《中国皮革》 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110433237A (en) * | 2019-09-18 | 2019-11-12 | 郑州伊品医药科技有限公司 | A kind of cream peace health-care patch and preparation method thereof |
CN111568632A (en) * | 2020-05-22 | 2020-08-25 | 天津缔道生物科技股份有限公司 | Preparation method of intelligent constant-temperature physiotherapy patch |
CN113577569A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Method for preparing far infrared physiotherapy plaster by irradiation foaming |
CN113577043A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Preparation process of far infrared physiotherapy plaster |
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