CN109420258A - Neutron capture treatment system - Google Patents
Neutron capture treatment system Download PDFInfo
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- CN109420258A CN109420258A CN201710733144.1A CN201710733144A CN109420258A CN 109420258 A CN109420258 A CN 109420258A CN 201710733144 A CN201710733144 A CN 201710733144A CN 109420258 A CN109420258 A CN 109420258A
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- 238000007493 shaping process Methods 0.000 claims abstract description 34
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- 230000015556 catabolic process Effects 0.000 claims abstract description 5
- 238000006731 degradation reaction Methods 0.000 claims abstract description 5
- 229910001245 Sb alloy Inorganic materials 0.000 claims description 12
- 239000002140 antimony alloy Substances 0.000 claims description 12
- 238000010521 absorption reaction Methods 0.000 claims description 10
- 238000005266 casting Methods 0.000 claims description 5
- 229910000838 Al alloy Inorganic materials 0.000 claims description 4
- 238000000465 moulding Methods 0.000 claims description 4
- 230000001225 therapeutic effect Effects 0.000 claims description 3
- 239000000956 alloy Substances 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 12
- 239000011162 core material Substances 0.000 description 48
- 230000005855 radiation Effects 0.000 description 13
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- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 10
- 229910052796 boron Inorganic materials 0.000 description 10
- 230000004888 barrier function Effects 0.000 description 9
- 238000010586 diagram Methods 0.000 description 9
- 229910052787 antimony Inorganic materials 0.000 description 7
- 238000013461 design Methods 0.000 description 7
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 description 6
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- 229910052751 metal Inorganic materials 0.000 description 3
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- GUTLYIVDDKVIGB-OUBTZVSYSA-N Cobalt-60 Chemical compound [60Co] GUTLYIVDDKVIGB-OUBTZVSYSA-N 0.000 description 1
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- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
- H05H3/06—Generating neutron beams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/109—Neutrons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1094—Shielding, protecting against radiation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/30—Nuclear fission reactors
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- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Pathology (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Radiation-Therapy Devices (AREA)
- Particle Accelerators (AREA)
Abstract
The application provides a kind of neutron capture treatment system, the neutron capture treatment system includes the accelerator for generating charged particle beam, the neutron generating unit of neutron beam is generated after charged particle beam irradiation, the beam-shaping body of shaping is carried out to neutron beam, the beam-shaping body includes slow body and the reflecting part for being coated on slow external week, the neutron generating unit generates neutron after charged particle beam irradiation, the slow body will be from the neutron degradation that neutron generating unit generates to default power spectrum, the reflecting part includes that the neutron that can be will deviate from is led back to improve the reflector of neutron intensity in default power spectrum and can form the supporting element supported to reflector.It is supported the creep effect to overcome lead material to lead material by the way that alloy material is arranged, the structural strength of beam-shaping body is improved in the case where not influencing neutron beam quality.
Description
Technical field
The present invention relates to a kind of radioactive ray treatment system more particularly to a kind of neutron capture treatment systems.
Background technique
As the radiation cures such as the development of atomics, such as cobalt 60, linear accelerator, electron beam have become cancer
One of the main means of disease treatment.However conventional photonic or electronic therapy are limited by radioactive ray physical condition itself, are being killed
While dead tumour cell, normal tissue a large amount of in beam approach can also be damaged；Additionally, due to tumour cell to putting
The difference of radiation-sensitive degree, traditional radiation therapy is for relatively having the malignant tumour of radiation resistance (such as: multirow glioblast
Tumor (glioblastoma multiforme), melanocytoma (melanoma)) treatment effect it is often bad.
Target therapy in order to reduce the radiation injury of tumour surrounding normal tissue, in chemotherapy (chemotherapy)
Concept is just applied in radiation cure；And it is directed to the tumour cell of radiation resistance, also actively development has high phase at present
To the radiation source of biological effect (relative biological effectiveness, RBE), as proton therapeutic, heavy particle are controlled
Treatment, neutron capture treatment etc..Wherein, neutron capture treatment is to combine above two concept, if boron neutron capture is treated, by
Boracic drug gathers in the specificity of tumour cell, and accurately neutron beam regulates and controls for cooperation, provides more better than conventional radiation
Treatment of cancer selection.
Boron neutron capture treatment (Boron Neutron Capture Therapy, BNCT) be using boracic (10B) drug
There is the characteristic of high capture cross section to thermal neutron, by10B(n,α)7Li neutron capture and nuclear fission reaction generate4He and7Li two
A heavy burden charged particle.It referring to Fig.1, is the schematic diagram of boron neutron capture reaction, the average energy of two charged particles is about
There is 2.33MeV High Linear to shift (Linear Energy Transfer, LET), short range feature, the linear energy of α particle
Transfer and range are respectively 150keV/ μm, 8 μm, and7Li heavy burden particle is then 175keV/ μm, 5 μm, and the integrated range of two particle is about
It is equivalent to a cell size, therefore the radiation injury for caused by organism can be confined to cell level, when boracic drug selects
It is gathered in tumour cell to selecting property, neutron appropriate of arranging in pairs or groups penetrates source, just can be before not normal tissue causes too major injury
It puts, achievees the purpose that tumour cell is killed in part.
In the treatment of accelerator boron neutron capture, the neutron or other particles that one side neutron generating unit generates, as γ is penetrated
Line has radioactivity, and the neutron that another aspect neutron generating unit generates is usually required to adjust power spectrum by beam-shaping body, be improved
Neutron yield rate, it is therefore desirable to install reflector to reduce particle radiation leakage rate, adjustment power spectrum and improve neutron yield rate.Lead or lead
Alloy is conventionally used for the material being reflected or shielded, however, the creep effect of lead is significant, can not provide structural rigidity and permanent
Service life.Metal (such as lead-antimony alloy) reduces creep effect using different additive ratios, improves structural strength,
It can be used as stacked structures object.It is common to be stacked using blocky lead-antimony alloy, it is applied to radiation shield.For boron neutron capture
For treatment, neutron beam quality is not only related with beam-shaping body, also related with reflector and shield.Since lead-antimony closes
Antimony in gold has high neutron absorption section, is reflecting layer according to lead-antimony alloy, can significantly reduce neutron beam quality.
If stacking lead can lead to structure because of the creep effect of lead although eliminating the antimony in high neutron absorption section for reflecting layer
Precision is insufficient, or even influences the safety of entire boron neutron capture treatment.
Summary of the invention
In order to solve the above technical problems, one aspect of the present invention provides a kind of neutron capture treatment system,
It can be improved beam-shaping body structural strength/precision under the premise of not significantly affecting neutron beam quality.The neutron capture is controlled
Treatment system includes that the neutron generation of neutron beam is generated for generating the accelerator of charged particle beam, after charged particle beam irradiation
Portion, the beam-shaping body that shaping is carried out to neutron beam, the beam-shaping body include slow body and are coated on slow external all
Reflecting part, the neutron generating unit generates neutron after charged particle beam irradiation, and the slow body will be produced from neutron generating unit
For raw neutron degradation to default power spectrum, the reflecting part includes that the neutron that can be will deviate from is led back to improve neutron in default power spectrum
The reflector of intensity and the supporting element that support can be formed to reflector.
Further, the reflecting part includes multiple lattice cells, and each lattice cell forms the core with accommodating space, more
A core connects to form the supporting element, and the reflector is set in the accommodating space of the core.
Further, the supporting element is an integral molding structure, and the reflector material casting is set to the core
In accommodating space.
Modularized design preferably is carried out to reflecting part as a kind of, specifically, the core using specified quantity connects shape
At supporting element, the outside of the supporting element is equipped with the top plate and bottom plate being oppositely arranged and connect and enclose with top plate and bottom plate and is set to
The side plate of core periphery, core, the reflector in core, top plate and bottom plate and the side plate shape of the specified quantity connection
At reflection module, the reflector module stack forms the reflecting part.In view of what is stacked between subsequent reflection module
Convenient, specified quantity described in this preferred embodiment is 20.
In order to reduce influence of the material of core, top plate and bottom plate and side plate to neutron beam quality to the greatest extent, in the application
The material of the core, top plate and bottom plate and side plate is the alloy material of low neutron absorption cross-section and low activation, the alloy material
The total volume of material accounts for the ratio of the reflector material volume less than 10%.
Preferably as one kind, the material of the reflector is lead, the material of the core, top plate and bottom plate and side plate
For aluminium alloy or lead-antimony alloy.
In order to solve the above technical problems, another aspect of the present invention provides a kind of neutron capture treatment system,
It can be improved beam-shaping body structural strength/precision under the premise of not significantly affecting neutron beam quality.The neutron capture
Therapeutic device includes the neutron production that neutron beam is generated for generating the accelerator of charged particle beam, after charged particle beam irradiation
Life portion, the beam-shaping body that shaping is carried out to neutron beam, the beam-shaping body include slow body and are coated on slow external
The reflecting part in week, the neutron generating unit generate neutron after charged particle beam irradiation, and the slow body will be from neutron generating unit
To default power spectrum, the neutron that the reflecting part will deviate from leads back to strong to improve the neutron in default power spectrum the neutron degradation of generation
Degree, the reflecting part periphery are also wrapped on shielding part, and the shielding part includes supporting element and the shield that is set in supporting element.
Further, the shielding part includes multiple lattice cells, and each lattice cell forms the core with accommodating space, institute
Shield is stated in the accommodating space of the core, multiple cores connect to form the supporting element, and the supporting element is integrated
Molding structure, the shield material casting are set in the accommodating space of the core.
As a kind of modularized design preferably is carried out to shielding part, specifically, the core of specified quantity is connected and to be formed
It is equipped with the top plate and bottom plate being oppositely arranged on the outside of supporting element and the side plate set on core periphery is connect and enclosed with top plate and bottom plate, institute
Core, the shield in core, top plate and bottom plate and the side plate for stating specified quantity connection form shielding module, described
Shield module stack forms the shielding part, and the shield material is lead, the core, top plate and bottom plate and side plate
Material is low neutron absorption cross-section and low-activation material, and the material total volume of the core, top plate and bottom plate and side plate accounts for described
The ratio of the material volume of reflector is less than 10%.The convenience stacked between module, institute in the application are shielded in view of subsequent
Stating specified quantity is 20.
Further, the reflecting part includes that the neutron that can be will deviate from is led back to improve neutron intensity in default power spectrum
Reflector and the supporting element that support can be formed to reflector.
Compared with prior art, supporting element or/and shielding of the application neutron capture treatment system by setting reflecting part
The supporting element in portion is supported reflecting material or/and shielding material, that is, passes through low neutron-absorbing and the alloy material of low activation
It is supported the creep effect to overcome lead material to lead material, improves beam in the case where not influencing neutron beam quality
The structural strength of shaping body.
Detailed description of the invention
Fig. 1 is the application boron neutron capture reaction schematic diagram；
Fig. 2 is the schematic diagram of the neutron capture treatment system for being installed on barrier shield in the embodiment of the present application one, is had
Shielding part, and only shielding part has supporting element；
Fig. 3 is the schematic diagram of the cored structure of the shielding part in the embodiment of the present application one；
Fig. 4 is to shield the decomposition diagram of module in the embodiment of the present application one under not set shield materials behavior；
Fig. 5 is the schematic diagram of the neutron capture treatment system for being installed on barrier shield in the embodiment of the present application two, wherein penetrating
Beam shaping body does not have shielding part, and only reflecting part has supporting element；
Fig. 6 is the schematic diagram of the cored structure of the reflecting part in the embodiment of the present application two；
Fig. 7 is to reflect the decomposition diagram of module under the not set reflector material state in the embodiment of the present application two；
Fig. 8 is the schematic diagram of the neutron capture treatment system for being installed on barrier shield in the embodiment of the present application three, wherein instead
It penetrates portion and shielding part all has supporting element.
Specific embodiment
The particle (such as neutron) that accelerator generates needs to install reflector to reduce particle radiation leakage rate, needs to install screen
Body is covered to provide radiation safety shielding.Lead or metal are conventionally used for the material being reflected or shielded, however, the creep of lead is imitated
Should be significant, structural rigidity and permanent service life can not be provided.Metal (such as lead-antimony alloy) uses different additive ratios
Example reduces creep effect, improves structural strength, can be used as stacked structures object.It is common to be stacked using blocky lead-antimony alloy, it answers
For radiation shield.For boron neutron capture treatment for, neutron beam quality is not only related with beam-shaping body, also with reflection
Body and shield are related.It is reflecting layer according to lead-antimony alloy since the antimony in lead-antimony alloy has high neutron absorption section,
Neutron quality can significantly be reduced.It, can be because of although eliminating the antimony in high neutron absorption section if stacking lead is reflecting layer
The creep effect of lead causes structure precision insufficient, or even influences the safety of entire boron neutron capture treatment.
As shown in Fig. 2, the application provides a kind of neutron capture treatment system 100, the neutron capture treatment system 100 is wrapped
The neutron generating unit for including accelerator 200 for generating charged particle beam P, generating after charged particle beam P irradiation neutron beam
10, the beam-shaping body 20 and collimator 30 of shaping are carried out to neutron beam.The beam-shaping body 20 include slow body 21,
It is coated on the reflecting part 22 in slow external week.The neutron generating unit 10 generates neutron beam N after charged particle beam irradiation, described
The neutron beam N generated from neutron generating unit 10 is decelerated to default power spectrum, the neutron that the reflecting part 22 will deviate from by slow body 21
It leads back to improve the neutron intensity in default power spectrum, the collimator 30 concentrates the neutron that neutron generating unit 10 generates.
As embodiment one, the neutron capture treatment system 100 further includes shielding part 40.In conjunction with Fig. 3, the shielding part
40 include supporting element 41 and the shield 42 being set in supporting element 41.The supporting element 41 includes multiple lattice cells 43, each grid
Member 43 forms the core 45 with accommodating space 44, and the shield 42 is set in the accommodating space 44, and multiple cores 45 connect
Form the supporting element 41.As a preferred embodiment, the supporting element 41 is an integral molding structure, the shield
Material is cast in the accommodating space 44 of each core 45 of the supporting element 41.
In conjunction with Fig. 4, the supporting element 41 formed using the connection of core 45 of specified quantity, supporting element 41 has the cross of hexagon
Section is readily formed and stacks.Top plate 46, bottom plate 47 and and the top plate being oppositely arranged are equipped in the outside of supporting element 41
46, bottom plate 47 connects and encloses four side plates 48 set on 45 periphery of core.The core 45 of the specified quantity connection is set to core
Shield 42, top plate 46, bottom plate 47 and side plate 48 in 45 form shielding module 49, and the shielding module 49 stacks shape
At the shielding part 40.In the application, it is contemplated that the convenience stacked between subsequent shielding module 49, reality as one preferred
Example is applied, the specified quantity is 20.Certainly, those skilled in the art can adjust the number of side plate according to the design needs, and such as 3
It is a, 6 etc.；The specified quantity of adjustment shielding module, such as 10,30 etc. according to the design needs.
The material of the shield 42 be lead, the top plate 46, bottom plate 47 and with top plate 46, bottom plate 47 and side plate 48
It is absorbed by low neutron cross section and the alloy material of low neutron activation is made.In order to reduce alloy material to the greatest extent to neutron beam quality
Influence, the total volume of the alloy material accounts for the ratio of 42 material volume of shield less than 10%.
In the present embodiment, reflecting part 22 is the structure made of lead material with creep effect, and shielding part 40 wraps
It is overlying on the periphery of the reflecting part 22, beam-shaping body 20 is embedded in for being shielded to the radiation for irradiating indoor generation
In barrier shield W, the shielding part 40 is supported directly upon the barrier shield W, and the supporting element 41 inside shielding part 40 is to shield 42
Strength support also is provided to reflecting part 22 while support is provided itself, so that the structure for improving entire beam-shaping body 20 is strong
Degree.
As shown in figure 5, the setting of the shielding part 40 in embodiment one is directly applied to reflecting part 22 as embodiment two
In, the reflecting part 22 is arranged to include supporting element 221 structure, and be not provided with shielding part 40.
In conjunction with Fig. 6, the reflecting part 22 includes supporting element 221 and the reflector 222 being set in supporting element 221.It is described
Supporting element 221 includes multiple lattice cells 223, and each lattice cell 223 forms the core 225 with accommodating space 224, the reflector
222 are set in the accommodating space 224, and multiple connections of core 225 form the supporting element 221.Embodiment party as one preferred
Formula, the supporting element 221 are integrally formed, and the material of the reflector 222 is cast in the core 225 of the supporting element 221.
As shown in fig. 7, modularized design is carried out to reflecting part 22, specifically, the core 225 using specified quantity connects shape
At supporting element 221, the outside of the supporting element 221 be equipped with the top plate 226 being oppositely arranged, bottom plate 227 and with top plate 226,
Bottom plate 227 connects and encloses four side plates 228 set on 225 periphery of core.The core 225 of the specified quantity connection is set to core
Reflector 222, top plate 226, bottom plate 227 and side plate 228 in portion 225 form reflection module 229, the reflection module
229 stackings form the reflecting part 22.It the top plate 226, bottom plate 227 and connect and encloses and be set to top plate 226, bottom plate 227
Four side plates 228 of 225 periphery of core are the alloy material of the absorption of low neutron cross section and low activation, the alloy material total volume
The ratio of 42 material volume of shield is accounted for less than 10%.
Fig. 8 show embodiments herein three, and place unlike the embodiments above is, in the present embodiment, reflecting part
It is the structure design with supporting element with shielding part, and in the present embodiment, reflecting part in the setting and embodiment two of reflecting part
Setting it is identical, as soon as the setting of shielding part is identical as the setting of shielding part in embodiment, text in no longer in detail narration.By beam
When shaping body 20 is embedded in barrier shield W, shielding part 40 is supported directly upon barrier shield W, which penetrates not influencing neutron
In the case where Shu Pinzhi, by be arranged supporting element 221 reflector 222 is supported, setting supporting element 41 to shield 42 into
Row support, to overcome the problems, such as that reflector and shield lead to structure precision because generating creep effect using lead material.
It should be pointed out that as described in embodiment two and embodiment three, when reflecting part is set as having reflection module
Structure when, since reflecting part 22 is coated on the periphery of the slow body 21, and the outer surface of slow body 21 is usually cylinder
Or at least one cone-shaped structure, therefore the reflecting part formed is stacked by reflection module 230 and is coated on slow body
When 21 outer surface, it is also contemplated that the combination problem in structure, to direct and slow 21 surface junction of body reflector
Module carries out structural adjustment, for example, by cutting with the reflection module of slow 21 contact portion of body, so that reflecting part is bonded
In the outer surface of slow body 21, so that the neutron for not influencing 222 pairs of reflector deviations in reflecting part 22 reflects.
The core that lattice cell described herein is formed can be any enclosed construction with poroid accommodating space, such as
Cross section is square, the geometry of triangle perhaps hexagon has the tetrahedron of poroid accommodating space, octahedron or
Dodecahedron is also possible to the non-enclosed structure with poroid accommodating space, just no longer illustrates one by one herein.The lead
It is set to by way of casting in the poroid accommodating space, and is surrounded by core material tight, so that core
Alloy material forms lead material and supports.
In the embodiment of the present application two and embodiment three, in order to reflect module and/or shield module stacking it is convenient with
And it is easily manufactured, the core of reflecting part and the core of shielding part are all made of the structure that cross section is hexagon.Certainly, the reflection
The structure of the supporting element in portion can also be different from the supporting piece structure of the shielding part.Such as the core knot of the supporting element of shielding part
Structure is the geometry that cross section is hexagon, and the cored structure of the supporting element of reflecting part is tetrahedron, as long as supporting element
Alloy material can form lead material and support, and generate minor impact to neutron beam quality, herein just no longer
Narration in detail.
No matter above any embodiment, consider, the core, top plate, bottom for entire beam-shaping body weight
Plate and the alloy material for selecting lighter weight set on the material of the side plate of core periphery is connect and enclosed with top plate and bottom plate, tie
Neutron beam quality is considered in conjunction, and the material of the core, top plate and bottom plate and side plate should also select low neutron absorber material
And low-activation material, and the material total volume of the top plate and bottom plate, side plate and core accounts for reflector material or accounts for shield
The ratio of material volume is less than 10%.In the application, the preferential aluminium of the material of the top plate and bottom plate, side plate and core is closed
Golden material.Also lead-antimony alloy substitution aluminium alloy can be used, because while the neutron absorption cross-section of lead-antimony alloy material is higher than
Aluminum alloy materials, but since the material total volume of the top plate and bottom plate, side plate and core accounts for reflector material or accounts for screen
The ratio of body material volume is covered less than 10%, and equivalent overall antimony content is less than 1%, therefore the antimony pair in lead-antimony alloy material
Neutron beam quality does not make significant difference yet.
Although the reflector or/and shield in herein described beam-shaping body are the lead material system with creep effect
At, but when beam-shaping body is embedded in the barrier shield W of exposure cell because be supported in barrier shield W reflector or/and
Shield can form support, therefore entire beam to the lead material with creep effect by supporting element made of alloy material
The structure precision of shaping body is improved.
On the one hand shielding part described herein passes through setting alloy material and is supported to lead material, on the other hand having
Alloy material support lead material periphery setting top plate, low plate and with top plate, low plate side plate interconnected, enhancing shield
The modularized design to shielding part is realized while portion's structural strength, structure is simple, therefore, can also be by the shielding part in the application
Occasion is shielded applied to other.
The beam-shaping body for neutron capture treatment that the application discloses is not limited to interior described in above embodiments
Structure represented by appearance and attached drawing.Done aobvious of material and shape and position on the basis of the application to wherein component and
Easy insight changes, substitution or modification, all this application claims within the scope of.
Claims (10)
1. a kind of neutron capture treatment system, it is characterised in that: the neutron capture treatment system includes for generating band electrochondria
The accelerator of beamlet, carries out shaping to neutron beam at the neutron generating unit that neutron beam is generated after charged particle beam irradiation
Beam-shaping body, the beam-shaping body include slow body and the reflecting part for being coated on slow external week, the neutron generating unit
Generate neutron after charged particle beam irradiation, the slow body by from the neutron degradation that neutron generating unit generates to default power spectrum,
The reflecting part includes that the neutron that can be will deviate from is led back to improve the reflector of neutron intensity in default power spectrum and can be right
Reflector forms the supporting element of support.
2. neutron capture treatment system according to claim 1, it is characterised in that: the reflecting part includes multiple lattice cells,
Each lattice cell forms the core with accommodating space, and multiple cores connect to form the supporting element, and the reflector is set to
In the accommodating space of the core.
3. neutron capture treatment system according to claim 2, it is characterised in that: the supporting element is integrally formed knot
Structure, the reflector material casting are set in the accommodating space of the core.
4. neutron capture treatment system according to claim 2, it is characterised in that: the core of specified quantity, which connects, to be formed
The supporting element, the supporting element outside are equipped with the top plate and bottom plate being oppositely arranged and connect and enclosed set on core with top plate and bottom plate
The side plate of portion periphery, the core of specified quantity connection, the reflector in the accommodating space of core, top plate and bottom plate with
And side plate forms reflection module, the reflector module stack forms the reflecting part.
5. neutron capture treatment system according to claim 4, it is characterised in that: the core, top plate and bottom plate and side
The material of plate is low neutron absorption cross-section and low-activation material, and the material total volume of the core, top plate and bottom plate and side plate accounts for
The ratio of the reflector material volume is less than 10%.
6. neutron capture treatment system according to claim 5, it is characterised in that: the material of the reflector is lead, institute
The material for stating core, top plate and bottom plate and side plate is aluminium alloy or lead-antimony alloy.
7. a kind of neutron capture treatment system, it is characterised in that: the neutron capture therapeutic device includes for generating band electrochondria
The accelerator of beamlet, carries out shaping to neutron beam at the neutron generating unit that neutron beam is generated after charged particle beam irradiation
Beam-shaping body, the beam-shaping body include slow body and the reflecting part for being coated on slow external week, the neutron generating unit
Generate neutron after charged particle beam irradiation, the slow body by from the neutron degradation that neutron generating unit generates to default power spectrum,
The neutron that the reflecting part will deviate from is led back to improve the neutron intensity in default power spectrum, and the reflecting part periphery is also wrapped on screen
Portion is covered, the shielding part includes the shield that can reflector formed the supporting element of support and is set in supporting element.
8. neutron capture treatment system according to claim 7, it is characterised in that: the shielding part includes multiple lattice cells,
Each lattice cell forms the core with accommodating space, and the shield is set in the accommodating space of the core, Duo Gexin
Portion connects to form the supporting element, and the supporting element is an integral molding structure, and the shield material casting is set to the core
In the accommodating space in portion.
9. neutron capture treatment system according to claim 7, it is characterised in that: the core of specified quantity, which connects, to be formed
The supporting element, the outside of the supporting element are equipped with the top plate and bottom plate being oppositely arranged and connect and enclose with top plate and bottom plate and be set to
The side plate of core periphery, core, the shield in core, top plate and bottom plate and the side plate shape of the specified quantity connection
At shielding module, the shield module stack forms the shielding part, and the shield material is lead, the core, top
The material of plate, bottom plate and side plate is low neutron absorption cross-section and low-activation material, the core, top plate and bottom plate and side plate
Material total volume account for the reflector material volume ratio less than 10%.
10. neutron capture treatment system according to claim 7, it is characterised in that: the reflecting part includes can will be inclined
From neutron lead back to improve the reflector of neutron intensity in default power spectrum and the supporting element of support can be formed to reflector.
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710733144.1A CN109420258B (en) | 2017-08-24 | 2017-08-24 | Neutron capture therapy system |
| CN202410064516.6A CN117839103A (en) | 2017-08-24 | 2017-08-24 | Beam shaping body |
| JP2020509150A JP7175964B2 (en) | 2017-08-24 | 2018-08-15 | Neutron capture therapy system |
| RU2020109214A RU2743972C1 (en) | 2017-08-24 | 2018-08-15 | Neutron capture therapy system |
| EP18847580.0A EP3666336B1 (en) | 2017-08-24 | 2018-08-15 | Neutron capture therapy system |
| EP21177917.8A EP3895760B1 (en) | 2017-08-24 | 2018-08-15 | Neutron capture therapy system |
| PCT/CN2018/100572 WO2019037624A1 (en) | 2017-08-24 | 2018-08-15 | Neutron capture therapy system |
| TW107129503A TWI683683B (en) | 2017-08-24 | 2018-08-23 | Neutron capture therapy system |
| US16/798,644 US11458336B2 (en) | 2017-08-24 | 2020-02-24 | Neutron capture therapy system comprising a beam shaping assembly configured to shape a neutron beam |
| US17/892,254 US11986680B2 (en) | 2017-08-24 | 2022-08-22 | Neutron capture therapy system comprising a beam shaping assembly configured to shape a neutron beam |
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| CN201710733144.1A CN109420258B (en) | 2017-08-24 | 2017-08-24 | Neutron capture therapy system |
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| TW201912201A (en) | 2019-04-01 |
| TWI683683B (en) | 2020-02-01 |
| CN109420258B (en) | 2024-02-23 |
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Application publication date: 20190305 Assignee: China boron (Xiamen) medical equipment Co.,Ltd. Assignor: NEUBORON MEDTECH LTD. Contract record no.: X2019320000054 Denomination of invention: Radiant ray detection system and radiant ray detection method for neutron capture treatment system License type: Common License Record date: 20190910 |
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