CN109420097A - The purposes of pharmaceutical composition in medicine preparation - Google Patents
The purposes of pharmaceutical composition in medicine preparation Download PDFInfo
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- CN109420097A CN109420097A CN201710736304.8A CN201710736304A CN109420097A CN 109420097 A CN109420097 A CN 109420097A CN 201710736304 A CN201710736304 A CN 201710736304A CN 109420097 A CN109420097 A CN 109420097A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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Abstract
The purposes that the present invention relates to pharmaceutical compositions in medicine preparation.The drug is for treating or preventing red swelling of the skin, described pharmaceutical composition obtains in the following way: the fruit of summer cypress of the corter pseudolaricis of 15~25 parts by weight, the tuber of stemona of 10~20 parts by weight, the big maple meat of 10~20 parts by weight, the kuh-seng of 15~25 parts by weight, the sulphur of 5~15 parts by weight, the honeycomb of 10~20 parts by weight, the rhizoma polygonati of 15~25 parts by weight, the camphor of 5~10 parts by weight and 10~20 parts by weight being carried out pulverization process, to obtain crushed mixture；The crushed mixture is added in 75% ethyl alcohol of 450~600 parts by weight, carries out immersion treatment, and to obtain immersion mixture, the soaking time is 20~30；The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.The pharmaceutical composition is Chinese medicine preparation, which can allow skin preferably to absorb medicine liquid ingredient, to eliminate red swelling of the skin as early as possible.
Description
Technical field
The present invention relates to drug fields, in particular it relates to the purposes of pharmaceutical composition in medicine preparation.
Background technique
People often meet with bite by mosquitos in summer and autumn, bite rear skin in itch redness state.Mosquito passes through it
Mouthpart stabs skin, and saliva or venom invade skin, and due to containing in the saliva of mosquito or the leachate of poison gland, there are many antigens
Ingredient, these antigens can generate allergic reaction with antibody after entering human skin and cause inflammation so as to cause pruitus
Redness locally generates the severe reactions such as bleb, hemorrhagic necrosis when serious, be summer dermatology common disease disease.
However, it is possible to which the method for effectively treating the red swelling of the skin after bite by mosquitos also needs further to study.
Summary of the invention
The application is to be made based on inventor to the discovery of following facts and problem and understanding:
Bite by mosquitos Related product is mostly puted prevention first with mosquito repellent liquid in the prior art, and the skin being used for after bite by mosquitos is repaired
Multiple drug is than sparser.Based on the above issues, inventor repairs mosquito by using professional Chinese medicine preparation pharmaceutical composition
Red swelling of the skin state after biting.Inventors have found that the Chinese medicine preparation composition can allow skin preferably to absorb medicine liquid ingredient,
To eliminate red swelling of the skin.
The present invention is directed to solve at least some of the technical problems in related technologies.
In the first aspect of the present invention, the invention proposes a kind of purposes of pharmaceutical composition in medicine preparation.According to
The embodiment of the present invention, for the drug for treating or preventing red swelling of the skin, described pharmaceutical composition is to obtain in the following way
: by the corter pseudolaricis of 15~25 parts by weight, the tuber of stemona of 10~20 parts by weight, the big maple meat of 10~20 parts by weight, 15~25
The kuh-seng of parts by weight, the sulphur of 5~15 parts by weight, the honeycomb of 10~20 parts by weight, the rhizoma polygonati of 15~25 parts by weight, 5~10 weights
The fruit of summer cypress of the camphor and 10~20 parts by weight of measuring part carries out pulverization process, to obtain crushed mixture；Described crush is mixed
It closes object to be added in 75% medical ethanol of 450~600 parts by weight, immersion treatment is carried out, to obtain immersion mixture, the leaching
Steeping the time is 20~30；The immersion mixture is filtered processing, takes its filtrate, to obtain the pharmaceutical composition
Object.According to an embodiment of the invention, the pharmaceutical composition be Chinese medicine preparation, the Chinese medicine preparation pharmaceutical composition can allow skin more
Medicine liquid ingredient is absorbed well, to eliminate red swelling of the skin as early as possible.
According to an embodiment of the invention, such use can also further comprise at least one following additional technical feature:
According to an embodiment of the invention, the red swelling of the skin is the red swelling of the skin after bite by mosquitos.Inventors have found that above-mentioned
Pharmaceutical composition is more significant to the red swelling of the skin therapeutic effect after bite by mosquitos.
According to an embodiment of the invention, described pharmaceutical composition obtains in the following way: by the soil of 20 parts by weight
Rose of Sharon skin, the tuber of stemona of 15 parts by weight, the big maple meat of 15 parts by weight, the kuh-seng of 20 parts by weight, the sulphur of 10 parts by weight, 15 parts by weight
Honeycomb, the rhizoma polygonati of 20 parts by weight, the camphor of 8 parts by weight and 15 parts by weight the fruit of summer cypress carry out pulverization process, to obtain powder
Broken mixture；The crushed mixture is added in 75% medical ethanol of 550 parts by weight, immersion treatment is carried out, to obtain
Immersion mixture, the soaking time are 25；The immersion mixture is filtered processing, takes its filtrate, to obtain
Described pharmaceutical composition.Inventors have found that the Chinese medicine preparation pharmaceutical composition obtained through the above way can allow skin more preferable
Ground absorbs medicine liquid ingredient, and the effect for eliminating red swelling of the skin is more excellent.
According to an embodiment of the invention, described pharmaceutical composition is in micella, albumin nano granular, liposome, capsule, ball
Agent, tablet, granule, liquid oral, paste, aerosol, spray, the form of tincture or patch.The preparation of pharmaceutical composition
Form is not limited to type cited by the application, as long as can be realized the preparation for the function of repairing red swelling of the skin in range of choice
Within.
According to a particular embodiment of the invention, described pharmaceutical composition is in tincture.Tincture preparation is simple, is easy to save.
According to a particular embodiment of the invention, described pharmaceutical composition is in patch.Patch is bonded skin, it is easier to fast direct
It connects and has an effect, detumescence effect is more preferable, and is disposable products, no cross contamination problem.
According to a particular embodiment of the invention, the patch is that described pharmaceutical composition is carried out to disposable filling formation
's.The patch is disposable products, no cross contamination problem.
It is described medication combined for treating or pre- the invention proposes a kind of medication combined in the second aspect of the present invention
Anti- red swelling of the skin.According to an embodiment of the invention, it is described it is medication combined include: the first pharmaceutical composition and the second drug, it is described
First pharmaceutical composition obtains in the following way: by the corter pseudolaricis of 15~25 parts by weight, 10~20 parts by weight the tuber of stemona,
The big maple meat of 10~20 parts by weight, the kuh-seng of 15~25 parts by weight, the sulphur of 5~15 parts by weight, 10~20 parts by weight bee
The fruit of summer cypress progress pulverization process in room, the rhizoma polygonati of 15~25 parts by weight, the camphor of 5~10 parts by weight and 10~20 parts by weight, with
Just crushed mixture is obtained；The crushed mixture is added in 75% medical ethanol of 450~600 parts by weight, is impregnated
Processing, to obtain immersion mixture, the soaking time is 20~30；The immersion mixture is filtered processing,
Its filtrate is taken, to obtain described pharmaceutical composition.Second drug is the drug different from the first pharmaceutical composition, described
Second drug is used for for treating or preventing red swelling of the skin.Inventors have found that this is medication combined, can quickly to eliminate skin red
Swollen, detumescence effect is more preferable.
According to an embodiment of the invention, said medicine joint can also further comprise following additional technical feature at least it
One:
According to an embodiment of the invention, second drug includes selected from least one of following: Herba portulacae, wild chrysanthemum,
Viola mandshurica, smilax.The selection of second drug is not limited to type cited by the application, as long as it is red to can be realized reparation skin
The drug of swollen function is within range of choice.
According to an embodiment of the invention, first pharmaceutical composition obtains in the following manner: by 20 parts by weight
Corter pseudolaricis, the tubers of stemona of 15 parts by weight, the big maple meat of 15 parts by weight, the kuh-seng of 20 parts by weight, 10 parts by weight sulphur, 15 weights
The fruit of summer cypress for measuring the honeycomb of part, the rhizoma polygonati of 20 parts by weight, the camphor of 8 parts by weight and 15 parts by weight carries out pulverization process, so as to
To crushed mixture；The crushed mixture is added in 75% medical ethanol of 550 parts by weight, carries out immersion treatment, so as to
Immersion mixture is obtained, the soaking time is 25；The immersion mixture is filtered processing, takes its filtrate, so as to
Obtain described pharmaceutical composition.Inventors have found that Chinese medicine preparation pharmaceutical composition can allow skin preferably to absorb medicine liquid ingredient,
To eliminate red swelling of the skin as early as possible.
According to a particular embodiment of the invention, the red swelling of the skin is the red swelling of the skin after bite by mosquitos.
According to a particular embodiment of the invention, first pharmaceutical composition is in tincture.Tincture preparation is simple, is easy to protect
It deposits.
According to a particular embodiment of the invention, first pharmaceutical composition is in patch.Patch is bonded skin, it is easier to fast
Speed is directly had an effect, and detumescence effect is more preferable.
In the third aspect of the present invention, the invention proposes a kind of medicine boxs.According to an embodiment of the invention, the medicine box is used
In treating or preventing red swelling of the skin, comprising: the first container is provided with the first pharmaceutical composition in the first container, and described the
One pharmaceutical composition is for example above-mentioned to be limited.Inventors have found that the use of the medicine box can quickly eliminate red swelling of the skin, detumescence effect
Fruit is more preferable.
According to an embodiment of the invention, above-mentioned medicine box can also further comprise at least one following additional technical feature:
According to a particular embodiment of the invention, first pharmaceutical composition is in tincture.Tincture preparation is simple, is easy to protect
It deposits.
According to a particular embodiment of the invention, first pharmaceutical composition is in patch.Patch is bonded skin, it is easier to fast
Speed is directly had an effect, and detumescence effect is more preferable, and is disposable products, no cross contamination problem.
According to an embodiment of the invention, the medicine box further comprises: second container is provided with not in the second container
It is same as the drug of the first pharmaceutical composition, the drug for being different from the first pharmaceutical composition, which has, treats or prevents red swelling of the skin
Function.
According to a particular embodiment of the invention, the medicine box is for treating or preventing the red swelling of the skin after bite by mosquitos.
Detailed description of the invention
Fig. 1 is according to embodiments of the present invention 1 pharmaceutical composition using effect control schematic diagram, wherein
A indicates the red swelling of the skin state before use,
B indicates the skin detumescence state after use；
Fig. 2 is according to embodiments of the present invention 2 pharmaceutical composition using effect control schematic diagram, wherein
A indicates the red swelling of the skin state before use,
B indicates the skin detumescence state after use；And
Fig. 3 is according to embodiments of the present invention 3 pharmaceutical composition using effect control schematic diagram, wherein
A indicates the red swelling of the skin state before use,
B indicates the skin detumescence state after use.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings.Below with reference to
The embodiment of attached drawing description is exemplary, it is intended to is used to explain the present invention, and is not considered as limiting the invention.
Term " micella " refers to that surfactant is soluble in water, when its concentration is lower in monomolecular dispersion or being attracted to
Surface tension is reduced on the surface of solution.It has been saturated and cannot inhale again when the concentration of surfactant increases to solution surface
When attached, the molecule of surfactant starts to be transferred to inside solution, due to the hydrophobic part of surfactant molecule and the parent of water
It is smaller with power, and the attraction between hydrophobic part is larger, when a certain concentration is reached, many surfactant molecules are (general
50~150) hydrophobic part just attract each other, association together, forms association body, this association body is known as micelle or glue
Beam, micelle have various shape, such as spherical, and stratiform is rodlike.
Term " albumin nano granular " refers to that albumin nano granular is to encapsulate or adsorb drug using albumin as carrier,
The solid sphere formed by solidifying separation.Due to albuminous material have safe and non-toxic, non-immunogenicity, can biology drop
The features such as solution, good biocompatibility, makes it have many advantages in drug transportation aspect tool
Term " liposome " (liposome) is a kind of artificial membrane.In water in phospholipid molecule hydrophilic head insertion water, rouge
Plastid hydrophobic tail stretches to air, and the spherical liposomes of the double-deck rouge molecule are formed after agitation, and 25~1000nm of diameter is differed.Lipid
Body can be used for transgenosis, or the drug of preparation, using liposome can and the characteristics of cell membrane fusion, drug is sent into intracellular
The definition of portion's biology: when amphiphatic molecule such as phosphatide and sphingolipid are scattered in water phase, the hydrophobic tail of molecule is tended to be gathered in one
It rises, avoids water phase, and hydrophilic head is exposed to water phase, forms the vesicle with bilayer structure, referred to as liposome.
Liposome is the closed particle with duplicature, and self assemble lipid molecule is encapsulated inner aqueous phase medium, can be divided into large and small more
Layer, few multilayer and unilamelar liposome, medical application are relatively mostly small unilamellar vesicle.
Term " capsule " (capsules), which is meant, is filled in hollow hard capsules or is sealed in elastomeric flexible for drug
Manufactured solid pharmaceutical preparation in capsule, the material for constituting above-mentioned hollow hard rubber softgel shell or elastomeric flexible capsule shells is gelatin, sweet
Oil, water and other medicinal materials, but the ratio of each ingredient is not quite similar, and preparation method is also different.
Term " pill " refers to that fine medicinal material powder or medicinal substances extract add spherical shape made of suitable bonding auxiliary material or class ball piece
Shape agent
Term " tablet " (tablets) means drug, pesticide and suitable auxiliary material sheet system made of preparation technique
Agent.It is made of raw medicine, filler, adsorbent, adhesive, lubricant, dispersing agent, wetting agent, disintegrating agent, fragrance, colorant etc..First will
Crushing material, granulation, it is dry, then sheet is made with tablet press machine, also some is not required to granulation and drying, is directly pressed into tablet.In piece
Require content accurate in agent quality, weight differential is small, and disintegration time or dissolution rate meet regulation, and hardness is appropriate, appearance beauty, color
Pool is good, meets sanitary inspection standard, stablize in regulation storage period property etc..Dosage is accurate, stable in physicochemical property, storage period compared with
It is long, use, transport and easy to carry, price be low, yield is high.
Term " granule " (Granules), which refers to, cooperates drug and suitable auxiliary material and manufactured granular formulations, and one
As can be divided into soluble granule, suspension granule and effervescency granule, if partial size in 105-500 micron range, again
Referred to as granula subtilis.It is mainly characterized by directly swallowing, and can also pour in water and drink into application and carrying are more convenient, molten
It is very fast with infiltration rate out.
Term " liquid oral " means mixture with unit dose package person, is grown up on the basis of decoction, injection
Novel form.
Term " paste " (paste), which refers to, decocts paste dosage-form made of concentration for drug water or vegetable oil.Have for oral administration
With two kinds of external application.
Term " aerosol " means that drug containing, lotion or suspension and suitable propellant are filled jointly and be encapsulated in special valve
In the pressure vessel of system, content object fog-like is sprayed by the pressure of propellant when use, for lung's sucking or straight
Connect the preparation for being sprayed onto cavity mucous membrane, skin and space disinfection.
Term " spray " (sprays) refers to be to be used as power with compressed air or inert gas, will with nonmetallic sprayer
The dosage form that medical fluid sprays.It is different from aerosol, the power that aerosol sprays drug is propellant, (now mostly not such as fluorochloroparaffins
With), hydrofluoroalkane, dimethyl ether etc..
Term " tincture " refers to crude drug is immersed in alcohol or chemicals are dissolved in alcohol made of medicament, such as run
Eggplant tincture, orange peel tincture, tincture of iodine etc., abbreviation tincture.
Term " patch " means Pasting on the skin, and drug can produce a kind of systemic or local action flake system
Agent.Modern transdermal absorption formulation is a kind of by skin absorption, and can need dosage by the state of an illness by controlled release mechanism, quickly, is held
Enter the patch or patch drug of whole body long.
Hereinafter, inventor is to the preparation method of pharmaceutical composition, the preparation method of preparation and pharmaceutical composition for controlling
Red swelling of the skin carries out further detailed description after treating bite by mosquitos.
Embodiment one
By the corter pseudolaricis of 15 parts by weight, the tuber of stemona of 10 parts by weight, the big maple meat of 10 parts by weight, the kuh-seng of 15 parts by weight, 5
The sulphur of parts by weight, the honeycomb of 10 parts by weight, the rhizoma polygonati of 15 parts by weight, the camphor of 5 parts by weight and 10 parts by weight the fruit of summer cypress into
Row pulverization process, to obtain crushed mixture；
The crushed mixture is added in 75% medical ethanol of 450 parts by weight, immersion treatment is carried out, to be soaked
Bubble mixt, the soaking time are 20；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.
The pharmaceutical composition Chinese medicine preparation pharmaceutical composition obtained by above-mentioned preparation method can allow skin preferably to be inhaled
Medicine liquid ingredient is received, to eliminate red swelling of the skin as early as possible.
The pharmaceutical composition obtained by the above method is coated at red swelling of the skin, skin can be eliminated within about 5 minutes or so
Skin is red and swollen, and detumescence effect is good, and specific effect picture is referring to attached drawing 1.
Embodiment two
By the corter pseudolaricis of 25 parts by weight, the tuber of stemona of 20 parts by weight, the big maple meat of 20 parts by weight, 25 parts by weight kuh-seng,
The sulphur of 15 parts by weight, the honeycomb of 20 parts by weight, the rhizoma polygonati of 25 parts by weight, the camphor of 10 parts by weight and 20 parts by weight the fruit of summer cypress
Pulverization process is carried out, to obtain crushed mixture；
The crushed mixture is added in 75% medical ethanol of 600 parts by weight, immersion treatment is carried out, to be soaked
Bubble mixt, the soaking time are 30；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.
The pharmaceutical composition Chinese medicine preparation pharmaceutical composition obtained by above-mentioned preparation method can allow skin preferably to be inhaled
Medicine liquid ingredient is received, eliminates red swelling of the skin as early as possible.
The pharmaceutical composition obtained by the above method is coated at red swelling of the skin, skin can be eliminated within about 5 minutes or so
Skin is red and swollen, and detumescence effect is good, and specific effect picture is referring to attached drawing 2.
Embodiment three
By the corter pseudolaricis of 20 parts by weight, the tuber of stemona of 15 parts by weight, the big maple meat of 15 parts by weight, 20 parts by weight kuh-seng,
The sulphur of 10 parts by weight, the honeycomb of 15 parts by weight, the rhizoma polygonati of 20 parts by weight, the camphor of 8 parts by weight and 15 parts by weight the fruit of summer cypress
Pulverization process is carried out, to obtain crushed mixture；
The crushed mixture is added in 75% medical ethanol of 550 parts by weight, immersion treatment is carried out, to be soaked
Bubble mixt, the soaking time are 25；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.
The pharmaceutical composition Chinese medicine preparation pharmaceutical composition obtained by above-mentioned preparation method can allow skin preferably to be inhaled
Medicine liquid ingredient is received, the effect for eliminating red swelling of the skin is more excellent.
The pharmaceutical composition obtained by the above method is coated at red swelling of the skin, skin can be eliminated within about 3~5 minutes
Redness, detumescence effect is more excellent, and specific effect picture is referring to attached drawing 3.
Example IV
The patch of preparation aforementioned pharmaceutical compositions can use new medical alcohol disinfecting piece packing machine and full-automatic alcohol
Cotton piece packing machine carries out, wherein the technical parameter of two kinds of packing machines is as shown in Table 1 and Table 2.
Table 1: new medical alcohol disinfecting piece packing machine
Table 2；Full-automatic alcohol cotton piece packing machine
| Device name | Full-automatic alcohol cotton piece packing machine |
| Specifications and models | JL-D220 |
| Speed of production | 50-120 packet/minute (double is double) |
| Package size | Long 45-150mm × wide 50-100mm |
| Wet tissue size | Long 80-220mm × wide 70-200mm |
| Folding mode | Longitudinal most 8 fold cross are to most 4 foldings |
| General power | 220V/50Hz/2.5kw |
| Outer dimension | Long 1000mm × wide 1500mm × high 2000mm |
| Weight of equipment | 900kg |
| Packaging material | Film |
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include at least one this feature.In the description of the present invention, the meaning of " plurality " is at least two, such as two, three
It is a etc., unless otherwise specifically defined.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office
It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field
Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples
It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, modifies, replacement and variant.
Claims (10)
1. the purposes of pharmaceutical composition in medicine preparation, the drug is for treating or preventing red swelling of the skin, the medicine group
Object is closed to obtain in the following way:
By the corter pseudolaricis of 15~25 parts by weight, the tuber of stemona of 10~20 parts by weight, 10~20 parts by weight big maple meat, 15~25 weights
Measure the kuh-seng of part, the sulphur of 5~15 parts by weight, the honeycomb of 10~20 parts by weight, the rhizoma polygonati of 15~25 parts by weight, 5~10 weight
The camphor of part and the fruit of summer cypress of 10~20 parts by weight carry out pulverization process, to obtain crushed mixture；
The crushed mixture is added in 75% ethyl alcohol of 450~600 parts by weight, immersion treatment is carried out, to be impregnated
Mixture, the soaking time are 20~30；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.
2. purposes according to claim 1, which is characterized in that the red swelling of the skin is the red swelling of the skin after bite by mosquitos.
3. purposes according to claim 1, which is characterized in that described pharmaceutical composition obtains in the following way:
By the corter pseudolaricis of 20 parts by weight, the tuber of stemona of 15 parts by weight, the big maple meat of 15 parts by weight, the kuh-seng of 20 parts by weight, 10 weights
The fruit of summer cypress for measuring the sulphur of part, the honeycomb of 15 parts by weight, the rhizoma polygonati of 20 parts by weight, the camphor of 8 parts by weight and 15 parts by weight carries out
Pulverization process, to obtain crushed mixture；
The crushed mixture is added in 75% ethyl alcohol of 550 parts by weight, carries out immersion treatment, to obtain impregnating mixing
Object, the soaking time are 25；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition.
4. purposes according to claim 1, which is characterized in that described pharmaceutical composition is in micella, albumin nano granular, rouge
Plastid, capsule, pill, tablet, granule, liquid oral, paste, aerosol, spray, the form of tincture or patch.
5. purposes according to claim 4, which is characterized in that described pharmaceutical composition is in tincture；
Preferably, described pharmaceutical composition is in patch.
6. purposes according to claim 5, which is characterized in that the patch is to carry out described pharmaceutical composition disposably
Filling formation.
7. it is a kind of medication combined, it is described medication combined for treating or preventing red swelling of the skin characterized by comprising the first medicine
Compositions, first pharmaceutical composition obtain in the following way:
By the corter pseudolaricis of 15~25 parts by weight, the tuber of stemona of 10~20 parts by weight, 10~20 parts by weight big maple meat, 15~25 weights
Measure the kuh-seng of part, the sulphur of 5~15 parts by weight, the honeycomb of 10~20 parts by weight, the rhizoma polygonati of 15~25 parts by weight, 5~10 weight
The camphor of part and the fruit of summer cypress of 10~20 parts by weight carry out pulverization process, to obtain crushed mixture；
The crushed mixture is added in 75% ethyl alcohol of 450~600 parts by weight, immersion treatment is carried out, to be impregnated
Mixture, the soaking time are 20~30；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition；
And second drug, second drug are the drug different from the first pharmaceutical composition, second drug is for controlling
Treat or prevent red swelling of the skin.
8. according to claim 7 medication combined, which is characterized in that second drug include selected from it is following at least it
One: Herba portulacae, wild chrysanthemum, viola mandshurica, smilax.
9. according to claim 7 medication combined, which is characterized in that first pharmaceutical composition is in the following manner
It obtains:
By the corter pseudolaricis of 20 parts by weight, the tuber of stemona of 15 parts by weight, the big maple meat of 15 parts by weight, the kuh-seng of 20 parts by weight, 10 weights
The fruit of summer cypress for measuring the sulphur of part, the honeycomb of 15 parts by weight, the rhizoma polygonati of 20 parts by weight, the camphor of 8 parts by weight and 15 parts by weight carries out
Pulverization process, to obtain crushed mixture；
The crushed mixture is added in 75% medical ethanol of 550 parts by weight, carries out immersion treatment, it is mixed to obtain impregnating
Object is closed, the soaking time is 25；
The immersion mixture is filtered processing, takes its filtrate, to obtain described pharmaceutical composition；
Preferably, the red swelling of the skin is the red swelling of the skin after bite by mosquitos；
Preferably, first pharmaceutical composition is in tincture；
Preferably, first pharmaceutical composition is in patch.
10. a kind of medicine box, which is characterized in that the medicine box is for treating or preventing red swelling of the skin, comprising:
The first container is provided with the first pharmaceutical composition, the first pharmaceutical composition such as claim 1 in the first container
Or defined in 3；
Preferably, first pharmaceutical composition is in tincture；
Preferably, first pharmaceutical composition is in patch；
Optionally, the medicine box further comprises:
Second container is provided with the drug different from the first pharmaceutical composition in the second container, described to be different from the first medicine
The drug of compositions has the function for the treatment of or prevention red swelling of the skin,
Preferably, the medicine box is for treating or preventing the red swelling of the skin after bite by mosquitos.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710736304.8A CN109420097A (en) | 2017-08-24 | 2017-08-24 | The purposes of pharmaceutical composition in medicine preparation |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710736304.8A CN109420097A (en) | 2017-08-24 | 2017-08-24 | The purposes of pharmaceutical composition in medicine preparation |
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| CN109420097A true CN109420097A (en) | 2019-03-05 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710736304.8A Pending CN109420097A (en) | 2017-08-24 | 2017-08-24 | The purposes of pharmaceutical composition in medicine preparation |
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| CN (1) | CN109420097A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1814225A (en) * | 2005-12-11 | 2006-08-09 | 赵桂荣 | External-use liquor for treating thinea corporis and tinea cruris |
| CN101347395A (en) * | 2008-09-12 | 2009-01-21 | 南京巴黎贝丽丝香水有限公司 | Chinese medicine floral water for preventing and treating bite by mosquitos |
| CN102366457A (en) * | 2011-10-24 | 2012-03-07 | 汕头市江源化工有限公司 | Tinea treating medicinal liquid and preparation method thereof |
-
2017
- 2017-08-24 CN CN201710736304.8A patent/CN109420097A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1814225A (en) * | 2005-12-11 | 2006-08-09 | 赵桂荣 | External-use liquor for treating thinea corporis and tinea cruris |
| CN101347395A (en) * | 2008-09-12 | 2009-01-21 | 南京巴黎贝丽丝香水有限公司 | Chinese medicine floral water for preventing and treating bite by mosquitos |
| CN102366457A (en) * | 2011-10-24 | 2012-03-07 | 汕头市江源化工有限公司 | Tinea treating medicinal liquid and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 崔力争等: "《儿童保健与健康》", 28 February 2013, 北京艺术与科学电子出版社 * |
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