CN109416460A - The variable microscope of operating distance - Google Patents
The variable microscope of operating distance Download PDFInfo
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- CN109416460A CN109416460A CN201780039986.5A CN201780039986A CN109416460A CN 109416460 A CN109416460 A CN 109416460A CN 201780039986 A CN201780039986 A CN 201780039986A CN 109416460 A CN109416460 A CN 109416460A
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- lens
- operating distance
- variable
- moveable
- distance
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B15/00—Optical objectives with means for varying the magnification
- G02B15/14—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective
- G02B15/16—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective with interdependent non-linearly related movements between one lens or lens group, and another lens or lens group
- G02B15/20—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective with interdependent non-linearly related movements between one lens or lens group, and another lens or lens group having an additional movable lens or lens group for varying the objective focal length
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/20—Surgical microscopes characterised by non-optical aspects
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B15/00—Optical objectives with means for varying the magnification
- G02B15/14—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective
- G02B15/143—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having three groups only
- G02B15/1431—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having three groups only the first group being positive
- G02B15/143105—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having three groups only the first group being positive arranged +-+
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/0012—Surgical microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/02—Objectives
- G02B21/025—Objectives with variable magnification
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
- G02B21/20—Binocular arrangements
- G02B21/22—Stereoscopic arrangements
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
- G02B21/244—Devices for focusing using image analysis techniques
Abstract
The invention discloses a kind of microscopical system and method that can be changed for operating distance.The variable microscope of the operating distance includes eyepiece；It is optically coupled to the biocular systems of the eyepiece；It is optically coupled to the continuous zoom stereo of the eyepiece and the biocular systems；And it is optically coupled to the lens system that the operating distance of the eyepiece, the continuous zoom stereo and the biocular systems can be changed.The variable lens system of the operating distance includes the first lens；With the second lens of the first lens located in series；And between first lens and second lens located in series moveable the third lens, the moveable the third lens are configured so that the variation of the distance between the moveable the third lens and first lens changes microscopical operating distance.
Description
Technical field
Present invention relates in general to optical microscopies, more particularly to the microscopical system of object lens that can be changed for operating distance
System and method.
Background technique
Optical microscopy is used in various applications to provide the Sample Image of amplification in field of microscope for user.Example
Such as, microscope can be used for performing the operation, laboratory and quality assurance application.Optical microscopy is put using visible light and lens system
Bulk specimen.
A type of optical microscopy is to share principal goods mirror microscope.The use of principal goods mirror microscope is shared in a pair of of eyepiece
The single shared principal goods mirror shared between lens system.
Summary of the invention
According to some embodiments of the present disclosure, a kind of microscope that operating distance is variable is disclosed.The operating distance can
The microscope of change includes eyepiece；It is optically coupled to the biocular systems of the eyepiece；It is optically coupled to the eyepiece and the binocular
The continuous zoom stereo of system；And it is optically coupled to the eyepiece, the continuous zoom stereo and described double
The variable lens system of the operating distance of mesh system.The variable lens system of the operating distance includes the first lens；With it is described
Second lens of the first lens located in series；And between first lens and second lens located in series it is removable
Dynamic the third lens, the moveable the third lens are configured so that the moveable the third lens with described first thoroughly
The variation of the distance between mirror changes microscopical operating distance.
According to another embodiment of the present disclosure, a kind of microscopic system that operating distance is variable is disclosed.The system
Including processor；It is couple to the imaging sensor of the processor；The operating distance for being optically coupled to described image sensor can
The lens system of change；And motor, the motor are couple to the processor and the moveable the third lens and are matched
The mobile the third lens are set to so that the received image of described image sensor focuses.The variable lens system of the operating distance
System includes the first lens；With the second lens of the first lens located in series；And in first lens and described second
The moveable the third lens of located in series between lens, the moveable the third lens are configured so that described removable
The third lens and the variations of the distance between first lens change microscopical operating distance.
According to the further embodiment of the disclosure, a kind of side that the microscope for keeping operating distance variable focuses is disclosed
Method.The method includes capturing image at the microscopical imaging sensor that operating distance can be changed, institute is handled by processor
Image is stated to determine whether described image is focus alignment；And change the position of moveable the third lens, until the work
Make the image focal point alignment at the microscopical eyepiece of distance variable.The variable microscope of the operating distance includes operating distance
Variable lens system.The variable lens system of the operating distance includes the first lens；With the first lens located in series
The second lens；And between first lens and second lens located in series moveable the third lens, institute
It states moveable the third lens and is configured so that the distance between the moveable the third lens and first lens
Variation changes microscopical operating distance.
Detailed description of the invention
In order to be more fully understood from the disclosure and its feature and advantage, referring now to the following theory carried out in conjunction with attached drawing
It is bright, in the accompanying drawings:
Fig. 1 is the shared microscopical schematic diagram of principal goods mirror for including the variable lens system of operating distance；
Fig. 2 is the schematic diagram of the variable lens system of the operating distance of Fig. 1；
Fig. 3 is the figure of the operating distance of the variable lens system of the operating distance of Fig. 1 and Fig. 2；
Fig. 4 is the operating distance of the variable lens system of operating distance shown in Fig. 3 and the figure of focal length；
Fig. 5 is the block diagram of the autofocus system of the variable lens system of operating distance shown in Fig. 1；And
Fig. 6 is the flow chart of the method for the lens system of operation element distance variable.
Specific embodiment
The disclosure provides the shared principal goods mirror microscope for the lens system that can be changed with operating distance, and the operating distance is variable
Lens system allow adjustable operating distance between microscope and sample, while keep whole interior in microscope away from
From sufficiently small, to allow to use microscope when execution activity at arm's length range, operation such as is executed to sample.Due to
When this microscope of user's manual focus, it has difficulties in terms of keeping focus, therefore shares principal goods mirror microscope and may be used also
To include autofocus system.
Referring to figs. 1 to Fig. 6 provide the embodiment of shared principal goods mirror microscope, its component and its application method into
One step explanation.
Fig. 1 is the shared microscopical schematic diagram of principal goods mirror for including the variable lens system of operating distance.Microscope 100 wraps
Include eyepiece 102a and 102b.Microscopical user checks the enlarged drawing of sample 104 by eyepiece 102.Sample 104 is in Fig. 1
In be shown as eyes, but can be any sample checked using microscope 100.Eyepiece 102a and 102b also can be replaced offer
The other component of the three-dimensional view of sample 104, such as two digital displays.
The image of sample 104 lens system 108 and variable by the stereoscopic lens system 106 of continuous zoom, operating distance
The series of biocular systems 126 is amplified.The variable lens system 108 of operating distance collects the light from sample 104.Continuous zoom
Stereoscopic lens system 106 may include one or more lens, and the lens can be moved relative to each other, to increase or reduce
Appear in the magnifying power of the image of the sample 104 of eyepiece 102.The stereoscopic lens system 106 of continuous zoom divides the image of sample 104
It is cut into three-dimensional view.Biocular systems 126 are further amplified image and provide image to user by eyepiece 102.
The variable lens system 108 of operating distance can replace shared principal goods mirror and may include being arranged to change to show
The lens 110,112 and 114 of the operating distance 116 of micro mirror 100.Operating distance 116 is the variable lens system 108 of operating distance
The distance between sample 104.Operating distance 116 provides space for the user of microscope 100 to execute behaviour to sample 104
Make.For example, operating distance 116 is made for surgeon when microscope 100 is for operation and sample 104 is operation target
The space of surgical action is executed with oneself hand and tool.Each user may be to operating distance according to any suitable variable
With different preferences, these variables include the figure of user, the movement to be executed on sample 104 type and be used for
The size for the tool that execution acts on sample 104.
Lens 110,112 and 114 can be with located in series.Change operating distance 116, it can be with mobile working distance variable
Lens 112 in lens system 108 are to change distance 118 and 120.Distance 118 is the distance between lens 110 and lens 112.
Distance 120 is the distance between lens 112 and lens 114.When lens 112 move between lens 110 and lens 114, work
Make the variation of distance 116, as being further explained in detail relative to Fig. 2 and Fig. 3.Although lens 110,112 and 114 are shown
For single lens, but each lens 110,112 and/or 114 can be single lens or compound lens.In addition, although in Fig. 1
The variable lens system 108 of operating distance illustratively comprises three lens, but the lens system 108 that operating distance can be changed can wrap
Include more than three lens.In addition, in the disclosure further including institute although only lens 112 move in the example being discussed herein
Have or system that more than one lens are movable within.
Microscope 100 can include additionally autofocus system 122, as shown in further detail in Fig. 5.Auto-focusing
System 122 may include one or more motors, imaging sensor and processor.Imaging sensor can be couple to beam splitter
124, to allow imaging sensor to capture the figure of sample 104 in motor mobile lens 112 in the position range of lens 112
Picture.Processor can execute software program, and the software program determines which of imaging sensor captured image is focus
Alignment.Once processor determines which image is focus alignment, processor can send a command to motor, by lens
112 are moved to the position of capture focus alignment image.
Fig. 2 is the schematic diagram of the variable lens system of the operating distance of Fig. 1.The variable lens system 200 of operating distance is wrapped
Include lens 110,112 and 114.Lens 110 and lens 114 can have fixed position so that lens 110 and lens 114 it
Between distance 222 will not change.Lens 112 can be moveable, so that the position of lens 112 is changeable, to change lens
The distance between 110 and lens 112 118 and the distance between lens 112 and lens 114 120.Distance 118 and distance 120 have
Inverse one-to-one relationship, so that distance 120 increases identical amount when distance 118 reduces a certain amount of.
The variation of the position of lens 112 can change the microscopical focal length for the lens system 200 that can be changed including operating distance
With resulting operating distance.According to the following formula, the variation of 112 position of lens can change effective focal power of lens 110, and thoroughly
Effective focal power of mirror 114 has Back Up:
φ123=φ12+φ3-φ12φ3(L-t1+d′12)
(1)
Wherein
f123The focal length of the variable lens system 200 of=operating distance；
t1The distance between=lens 110 and lens 112 118；
t2=L-t1The distance between=lens 112 and lens 114 120；
φ12=φ1+φ2-φ1φ2t1The inverse of the combined focal length of=lens 110 and lens 112；
φ1The inverse of the focal length of=lens 110；
φ2The inverse of the focal length of=lens 112；And
φ3The inverse of the focal length of=lens 114.
The combination of two lens such as 110 lens 112 of lens, obtains the lens proportional to the change in location of lens 112
The linear change of total focal power.In order to obtain the large change of operating distance 116 and do not have to the lens 108 for making operating distance variable and have
Have and be equal to the size that operating distance 116 changes, the third lens 114 can be added.Therefore, variable and formula 1 are combined into individually
Formula obtains the formula of the combination inverse of the focal length of the variable lens system 200 of following operating distance:
Lens 110,112 and 114 can have lens peculiarity and be arranged so that the smaller of distance 118 and distance 120
Variation will lead to the focal length of the variable lens system 200 of operating distance and the large change of operating distance.For example, can be by iteration
Computer program is used to solve the combination of lens 110,112 and 114, so that minimizing distance 222 and therefore minimum chemical industry
When making the overall dimensions of lens system 200 of distance variable, the range of the operating distance of the variable lens system 200 of operating distance
It is maximized.
This iterative computing method program can be used in autofocus system 122.It can be changed in conjunction with more complicated operating distance
The revision of these formula can be used in the autofocus system 122 that lens system 108 uses, these revisions consider
Supplementary lens or the ability of more than one lens movement.Iterative computing method program can also be used to solve the public affairs of these modifications
Formula, so that the range of operating distance is maximized when the distance between one or more lens minimize.More relative to Fig. 5
Autofocus system 122 is described in detail.
Fig. 3 is the figure of the operating distance of the variable lens system of the operating distance of Fig. 1 and Fig. 2.It is exemplary shown in Fig. 3
Operating distance lens system includes three lens.Lens 110 have 300 millimeters of focal length, and lens 112 have 115 millimeters of coke
Away from, and lens 114 have -100 millimeters of focal length.The overall dimensions distance 222 of the variable lens system of operating distance is 25
Millimeter.
Fig. 3 shows three positions of lens 112.At position 302, lens 112 be oriented than lens 114 closer to
Lens 110, so that distance 118 is less than distance 120.At position 304, lens 112 be positioned in lens 110 and lens 114 it
Between, so that distance 118 is substantially equal to distance 120.At position 306, lens 112 are oriented than lens 114 further from lens
110, so that distance 118 is greater than distance 120.As shown in Figure 3, when lens 112 are mobile close to lens 110, in the x-axis of Fig. 3
The operating distance shown reduces.When lens 112 are mobile close to lens 114, operating distance increases.
The lens used in the variable lens system of the operating distance of Fig. 1 to 3, which are to aid in, illustrates disclosure behind principle
Example.Lens with other focal lengths can be satisfactorily used with the variable lens system 108 of operating distance.In addition, can incite somebody to action
More than three lens are used for the lens system 108 that operating distance can be changed.Lens can have lens peculiarity and be arranged to cause
The variation that about 150 millimeters of operating distance.Lens can have lens peculiarity and be arranged so that operating distance range from big
About 125 millimeters to about 275 millimeters.Autofocus system 122 is particularly useful in microscope 100, and the microscope is working
Three lens shown in the total lens ratio Fig. 1 to 3 for including in the lens system 108 of distance variable are more, or described aobvious
In micro mirror, more than one lens are moveable in the variable lens system 108 of operating distance.Such system may be for the mankind
For be difficult to very much focus.
Fig. 4 is the operating distance of the variable lens system of operating distance shown in Fig. 3 and the figure of focal length.In the figure thoroughly
The distance between mirror 110 and lens 112 are shown in x-axis.The distance between lens 110 and lens 112 are at about 5 millimeters and big
Change between about 15 millimeters.One line representative can be changed saturating with the operating distance of the variation of distance between lens 110 and lens 112
The operating distance of mirror system.Operating distance range is from about 168 millimeters to about 256 millimeter.Another line is represented with lens 110
The focal length of the variable lens system of the operating distance of the variation of distance between lens 112.Focal range from about 226 millimeters to
About 307 millimeters.Therefore, about 10 millimeters of variation of the position of lens 112 will lead to about 90 millimeters of operating distance of change
Change and about 80 millimeters of focal length of variation.How the small change that Fig. 4 shows distance between lens 110 and lens 112 is led
Cause the large change of operating distance and focal length.
Fig. 5 is the block diagram of the autofocus system of the variable lens system of operating distance shown in Fig. 1.Auto-focusing system
System 122 may include computing subsystem 510, motor 515, imaging sensor 520, monitor 560 and communication link 565.Horse
Movable lens in the variable lens system of operating distance can be couple to up to 515, the lens 112 in such as Fig. 2.Horse can be started
Up to 515 to change the position of movable lens and therefore change the operating distance of the variable lens system of operating distance.Motor
515 can be the motor of any suitable type, including stepper motor, electric motor, servo motor, revolving actuator, linear activated
Device or any combination thereof.The position of movable lens may be recorded in lens position data 555, be detailed further below.
Imaging sensor 520 can capture the image of sample, all samples 104 as shown in Figure 1 in field of microscope.
Then image transmitting can be stored as image data 550 by imaging sensor 520 to computing subsystem 510, as follows further
It is described in detail.Image data 550 can be additionally included in information relevant to the position of movable lens when image is captured.Image passes
Sensor 520 can be any electronic equipment that can convert light to digital picture.For example, it can be digital camera, light-number
Word sensor, semiconductor charge-coupled device (CCD)), complementary metal oxide semiconductor (CMOS) device, N-type metal oxide
Semiconductor (NMOS) device contains another electricity of photodiode array as a part of one or more integrated circuits
Sub-device.Imaging sensor 520 may include supplementary lens or other elements are captured with assistant images.Imaging sensor 520 produces
The raw digital picture with enough resolution ratio is to generate available amendment image, even if being after image processing also such.
All or part of of computing subsystem 510 can be used as the component of microscope 100 or independently of the microscope
Or independently of any other operation of components shown in Fig. 1.Computing subsystem 510 may include being coupled in communication by bus 540
Processor 525, memory 530 and i/o controller 535.Processor 525 may include hard for what is executed instruction
Part, such as those of composition computer program such as application program 545.In a manner of property for example and not limitation, in order to execute instruction,
Processor 525 can retrieve (or acquisition) instruction from internal register, inner buffer and/or memory 530；By these instruction solutions
Code simultaneously executes；And internal register, inner buffer and/or memory 530 then is written into one or more results.The disclosure
Imagine under applicable circumstances, processor 525 includes any appropriate number of any suitable internal register.In applicable feelings
Under condition, processor 525 may include one or more arithmetic logic unit (ALU)；For multi-core processor；Or including one or more
A processor 260.Although this disclosure simultaneously shows par-ticular processor, the disclosure contemplates any suitable processor.
Processor 525 can execute instruction, such as so that the lens system auto-focusing that operating distance can be changed.For example, place
Manage device 525 can by execute or interpretation software, script, program, function, executable file or be included in application program 545 in
Other modules run application program 545.Processor 525 can execute one or more operations relevant to Fig. 6.By handling
The received input data of device 525 may include image data 550 and lens position number by the output data that processor 525 generates
According to 555.
Memory 530 may include, for example, random access memory (RAM), storage equipment are (for example, writeable read-only storage
Device (ROM) or other storage equipment), hard disk, solid storage device or other kinds of storage medium.By from another source (example
Such as, from CD-ROM, by data network from another computer equipment or otherwise) loading procedure, by computing subsystem
510 pre-programmeds or programming (and reprograming).I/o controller 535 can be couple to input-output apparatus (for example, prison
Visual organ 560, motor 515, imaging sensor 520, mouse, keyboard or other input-output apparatus) and it is couple to communication link
565.Input-output apparatus can receive and transmit data by communication link 565 in the form of analog or digital.
Memory 530 can store it is relevant to operating system, computer applied algorithm and other resources instruction (for example,
Computer code).Memory 530 can also store can be by the one or more application program that runs on computing subsystem 510
Or application data and data object that virtual machine is explained.For example, image data 550, lens position data 555 and apply journey
Sequence 545 is storable in memory 530.In some embodiments, it may include additional or different for calculating the memory of equipment
Data, application program, model or other information.
Image data 550 may include information relevant to 520 captured image of imaging sensor is passed through, and the information can
For determining whether image is focus alignment.Lens position data 555 may include in the lens system that can be changed with operating distance
The relevant information in the position of movable lens, all lens 112 as shown in Figure 2.Lens position data 555 can be with image data
Each image in 550 is related, and computing subsystem is allowed to determine the position of movable lens for each captured image.Come
It can be used for calculating the position of movable lens from the value of image data 550 and lens position data 555, wherein using operating distance
The image that variable lens system is checked is focus alignment.
Application program 545 may include software application, script, program, function, executable file or can be by processor
525 other modules explained or executed.Application program 545 may include the instruction of machine-readable, these instructions are for executing
One or more operations relevant to Fig. 6.Application program 545 may include machine readable instruction, these instructions are for calculating
It when is that focus is aligned by the image that the lens system that operating distance can be changed is checked.For example, application program 545 can be configured
At analysis image data 550 to determine when the variable lens system of operating distance is that focus is aligned.Application program 545 can be with
It generates output data and output data is stored in memory 530, another local medium or one or more remote equipment (examples
Such as, by sending output data via communication link 565) in.
Communication link 565 may include any kind of communication channel, connector, data communication network or other links.
For example, communication link 565 may include that wirelessly or non-wirelessly network, local area network (LAN), wide area network (WAN), dedicated network are public
Network (such as internet), wireless network, comprising satellite link, serial link, Radio Link (for example, infrared ray, radio frequency or its
He), the network or other kinds of data communication network of parallel link.
Processor 525 can order motor 515 mobile movable lens (lens 112 in such as Fig. 1 to 3) pass through it is removable
A series of positions of dynamic lens.Although motor 515 changes the position of movable lens, imaging sensor 520 can recorde can
One or more images at each position of mobile lens.Image is storable in image data 550, and corresponding with image
Lens position is storable in lens position data 555.Processor 525 then can be with executing application 545 to determine image
Which image in data 550 is focus alignment.Once application program 545 determines that focus is directed at image, application program 545 is just
It can determine the position of the movable lens of capture focus alignment image on it.Processor 525 then can order motor 515
Movable lens are moved to the position that image is focus alignment.
Fig. 6 is the flow chart of the method for the lens system of operation element distance variable.The step of method 600, can be by people, each
Kind computer program, model or any combination thereof execute, and the method is configured to control and analyze from microscopic system, fills
Set the information with equipment.Program and model may include the instruction being stored on computer-readable medium, and be performed
It can be operated later to execute one or more of steps described below.Computer-readable medium may include being configured to deposit
Storage and search program or any system, device or equipment of instruction, such as hard disk drive, CD, flash memories or any
Other suitable equipment.Program and model can be configured to instruction processor or other suitable units are retrieved and executed from meter
The instruction of calculation machine readable medium.For example, program and model can be an application program in application program 545 shown in Fig. 5.
For ease of description, method 600 is described relative to microscope similar with microscope 100 shown in Fig. 1；However, method
600 can be used for focusing the variable microscopical image of any operating distance.
Method 600 can be since step 602, and wherein the variable microscopical user of operating distance can position microscope
Above sample.It is the comfortable position of ergonomics for user's execution task that microscope can be located in by user
Place.For example, can be compared with the position of position finding microscope with the biggish user of type, the lesser user of figure can position microscope
At the position closer to sample.
In step 604, user or autofocus system can capture the image of sample.Imaging sensor can be used to catch
Obtain image or can by checked by eyepiece sample user capture image.Autofocus system can be pressed micro- by user
Button starting on mirror.
In step 606, user or autofocus system can determine whether image is focus alignment.User can pass through
It checks image and determines image whether there appears to be focus alignment to determine whether image is focus alignment.Autofocus system can
Determine whether image is focus alignment by executing the software application of analysis image sharpness.If image is focus alignment
, then method 600 may proceed to step 608, and wherein movable lens are positioned at the position of capture image.If image is not
It is that focus is aligned, then method 600 may proceed to step 610.
In step 610, user or autofocus system can change and move in the variable lens system of operating distance
The position of lens.User can change the position of movable lens by adjusting the control on microscope.Autofocus system
The position of movable lens can be changed by starter motor.Motor can be couple to movable lens, and when being activated, can
To change the position of movable lens.
In step 612, user or autofocus system can recorde the position of movable lens.User can pass through note
Record position is carried out in the position of control on lower microscope.Autofocus system can in the database of computing subsystem record position.
Method 600 may then return to step 604 to capture image in the current location of movable lens.
Without departing from the scope of the disclosure, method 600 can be modified, adds or is omitted.For example, step
Rapid sequence can be different from the mode mode execute and some steps can be performed simultaneously.In addition, not departing from this public affairs
In the case where the range opened, each individually step may include additional step.
Claims (17)
1. a kind of variable microscope of operating distance, comprising:
Eyepiece；
It is optically coupled to the biocular systems of the eyepiece；
It is optically coupled to the continuous zoom stereo of the eyepiece and the biocular systems；And
The operating distance for being optically coupled to the eyepiece, the continuous zoom stereo and the biocular systems is variable
Lens system；The variable lens system of the operating distance includes:
First lens；
With the second lens of the first lens located in series；And
The moveable the third lens of located in series between first lens and second lens, described moveable
It is micro- that three lens are configured so that the variation of the distance between the moveable the third lens and first lens changes
The operating distance of mirror.
2. the variable microscope of operating distance as described in claim 1, wherein the moveable the third lens include being matched
It is set to movable independently multiple lens.
3. the variable microscope of operating distance as described in claim 1, in which:
First lens have positive focal length；
Second lens have negative focal length；And
The moveable the third lens have positive focal length.
4. the variable microscope of operating distance as described in claim 1, wherein the operating distance can be at 125 millimeters and 275
Change between millimeter.
5. the variable microscope of operating distance as described in claim 1, wherein in first lens and second lens
At least one be can be movable independently.
6. a kind of variable microscopic system of operating distance, comprising:
Processor；
It is couple to the imaging sensor of the processor；
It is optically coupled to the variable lens system of the operating distance of described image sensor, the variable lens system of the operating distance
System includes:
First lens；
With the second lens of the first lens located in series；And
The moveable the third lens of located in series between first lens and second lens, described moveable
It is micro- that three lens are configured so that the variation of the distance between the moveable the third lens and first lens changes
The operating distance of mirror；And
Motor, the motor are couple to the processor and the moveable the third lens and are configured to move described
Three lens are so that the received image of described image sensor focuses.
7. the variable microscopic system of operating distance as claimed in claim 7, wherein the moveable the third lens include
It is configured to movable independently multiple lens.
8. the variable microscopic system of operating distance as claimed in claim 7, in which:
First lens have positive focal length；
Second lens have negative focal length；And
The moveable the third lens have positive focal length.
9. the variable microscopic system of operating distance as claimed in claim 7, wherein the operating distance can be at 125 millimeters
With 275 millimeters between change.
10. the variable microscopic system of operating distance as claimed in claim 7, wherein first lens and described second
At least one of lens are can be movable independently.
11. a kind of for the variable microscopical method of operating distance of focusing, comprising:
Image is captured at the microscopical imaging sensor that operating distance can be changed, the variable microscope of the operating distance includes
The variable lens system of operating distance, the variable lens system of the operating distance include:
First lens；
With the second lens of the first lens located in series；And
The moveable the third lens of located in series between first lens and second lens, described moveable
It is micro- that three lens are configured so that the variation of the distance between the moveable the third lens and first lens changes
The operating distance of mirror；
Described image is handled by processor to determine whether described image is focus alignment；And
Change the position of moveable the third lens, until the image focal point at the microscopical eyepiece that the operating distance can be changed
Alignment.
12. method as claimed in claim 13, further comprises:
Sweep multiple positions of the moveable the third lens；
Image is captured at each of the multiple position of moveable the third lens place；And
Described image is handled to determine which of described image is that focus is aligned.
13. method as claimed in claim 14, further comprises:
Record captures the position of the moveable the third lens of each image；And
The moveable the third lens are moved to the corresponding position of image being aligned with focus.
14. method as claimed in claim 13, wherein the moveable the third lens are movable independently including being configured to
Multiple lens.
15. method as claimed in claim 13, in which:
First lens have positive focal length；
Second lens have negative focal length；And
The moveable the third lens have positive focal length.
16. method as claimed in claim 13, wherein the operating distance changes 150 millimeters.
17. method as claimed in claim 13, wherein the operating distance can change between 125 millimeters and 275 millimeters.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662361270P | 2016-07-12 | 2016-07-12 | |
| US62/361,270 | 2016-07-12 | ||
| PCT/IB2017/053572 WO2018011644A1 (en) | 2016-07-12 | 2017-06-15 | Variable working distance microscope |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109416460A true CN109416460A (en) | 2019-03-01 |
Family
ID=59227783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780039986.5A Pending CN109416460A (en) | 2016-07-12 | 2017-06-15 | The variable microscope of operating distance |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20180017776A1 (en) |
| EP (1) | EP3443400A1 (en) |
| JP (1) | JP2019525231A (en) |
| CN (1) | CN109416460A (en) |
| AU (1) | AU2017296254A1 (en) |
| CA (1) | CA3024401A1 (en) |
| WO (1) | WO2018011644A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116699820B (en) * | 2023-08-04 | 2023-11-28 | 杭州安劼医学科技有限公司 | Imaging lens group of operation microscope |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1196392B (en) * | 1963-07-06 | 1965-07-08 | Leitz Ernst Gmbh | Pancratic lens for microscopes |
| DE102004052253B4 (en) * | 2003-12-10 | 2018-02-08 | Carl Zeiss Meditec Ag | Lens for a surgical microscope, surgical microscope and method for adjusting a lens |
| DE102005011781B4 (en) * | 2005-03-11 | 2007-06-06 | Carl Zeiss Surgical Gmbh | Ophthalmic surgical microscope with focus offset |
| DE102013219379B3 (en) * | 2013-09-26 | 2015-03-12 | Carl Zeiss Meditec Ag | Optical imaging system |
-
2017
- 2017-06-15 JP JP2019500646A patent/JP2019525231A/en active Pending
- 2017-06-15 AU AU2017296254A patent/AU2017296254A1/en not_active Abandoned
- 2017-06-15 US US15/624,248 patent/US20180017776A1/en not_active Abandoned
- 2017-06-15 EP EP17733541.1A patent/EP3443400A1/en not_active Withdrawn
- 2017-06-15 CA CA3024401A patent/CA3024401A1/en not_active Abandoned
- 2017-06-15 CN CN201780039986.5A patent/CN109416460A/en active Pending
- 2017-06-15 WO PCT/IB2017/053572 patent/WO2018011644A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017296254A1 (en) | 2018-11-29 |
| JP2019525231A (en) | 2019-09-05 |
| EP3443400A1 (en) | 2019-02-20 |
| CA3024401A1 (en) | 2018-01-18 |
| WO2018011644A1 (en) | 2018-01-18 |
| US20180017776A1 (en) | 2018-01-18 |
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Application publication date: 20190301 |