CN109398980A - A kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application method - Google Patents
A kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application method Download PDFInfo
- Publication number
- CN109398980A CN109398980A CN201811251886.1A CN201811251886A CN109398980A CN 109398980 A CN109398980 A CN 109398980A CN 201811251886 A CN201811251886 A CN 201811251886A CN 109398980 A CN109398980 A CN 109398980A
- Authority
- CN
- China
- Prior art keywords
- medicinal extract
- collet
- extract tank
- chinese medicine
- tank liner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 57
- 239000003814 drug Substances 0.000 title claims abstract description 34
- 238000000605 extraction Methods 0.000 title claims abstract description 29
- 239000006071 cream Substances 0.000 claims abstract description 23
- 238000003756 stirring Methods 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 24
- 238000004140 cleaning Methods 0.000 claims description 21
- 230000001954 sterilising effect Effects 0.000 claims description 16
- 238000010438 heat treatment Methods 0.000 claims description 13
- 238000004659 sterilization and disinfection Methods 0.000 claims description 12
- 239000003638 chemical reducing agent Substances 0.000 claims description 11
- 238000003860 storage Methods 0.000 claims description 9
- 239000007921 spray Substances 0.000 claims description 7
- 238000007599 discharging Methods 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- 238000010792 warming Methods 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims 2
- 230000005611 electricity Effects 0.000 claims 1
- 239000008399 tap water Substances 0.000 claims 1
- 235000020679 tap water Nutrition 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000002398 materia medica Substances 0.000 description 3
- 239000000498 cooling water Substances 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 235000021186 dishes Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000009628 steelmaking Methods 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000005491 wire drawing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D88/00—Large containers
- B65D88/74—Large containers having means for heating, cooling, aerating or other conditioning of contents
- B65D88/744—Large containers having means for heating, cooling, aerating or other conditioning of contents heating or cooling through the walls or internal parts of the container, e.g. circulation of fluid inside the walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0053—Details of the reactor
- B01J19/0066—Stirrers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D88/00—Large containers
- B65D88/54—Large containers characterised by means facilitating filling or emptying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D90/00—Component parts, details or accessories for large containers
- B65D90/0093—Devices for cleaning the internal surfaces of the container and forming part of the container
Abstract
The invention discloses a kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application methods, including medicinal extract tank liner, the upper cover being arranged at the top of medicinal extract tank liner, the lower head that medicinal extract tank liner at the bottom is arranged in and the stirring system at the top of upper cover and being used to be stirred the medicinal extract in medicinal extract tank liner is set, medicinal extract tank collet is equipped on the outside of the medicinal extract tank liner, the upper cover is equipped with inlet, the lower head bottom is equipped with discharge port, the medicinal extract tank collet upper end is suitable for reading equipped with collet, and bottom is equipped with mouth under collet.The beneficial effects of the present invention are: after using traditional Chinese medicine extraction medicinal extract holding vessel, the receipts cream process investment solved in traditional Chinese medicine extraction is big, puzzlement in place can not be executed, and greatly change the process equipment selection that Chinese medicine receives cream process, increase the multiple choices for extracting the workshop conceptual level, keeps workshop arrangement more economical practical.
Description
Technical field
The present invention relates to traditional Chinese medicine extraction medicinal extract storage facilities technical fields, and in particular to a kind of traditional Chinese medicine extraction medicinal extract holding vessel
And its application method.
Background technique
Traditional Chinese medicine extraction process is one of the key link in Chinese materia medica preparation production process, Chinese medical extract --- medicinal extract it is excellent
It is bad to directly influence drug quality, the utilization rate of herb resource, production efficiency and economic interests.The wherein receipts cream problem one of medicinal extract
It is directly the hot issue paid close attention to by vast traditional Chinese medicine enterprise.
The Article 11 of Chinese materia medica preparation annex proposes receipts cream process and clearly requires:
" traditional Chinese medicine extraction, concentration receive cream process and preferably closed system are used to be operated, and are cleaned online, with prevent pollution and
Cross contamination.Using closed system production, operating environment can be in non-clean area；It is produced, is operated using open mode
Environment should be adapted with the cleanliness class in its preparation formulation operations area."
For Chinese materia medica preparation mainly based on oral solid formulation, production rank is D grades.It is more due to extracting workshop appliance arrangement, and
Based on Class A workshop, cream process will be received and be arranged in D grades of clean areas, often larger difficulty is brought to technology arrangement, increase simultaneously
Extract the air conditioning energy consumption in workshop.
Therefore cream is received using in non-clean area at present by most of enterprise, but laminar flow trolley is arranged in inspissator medicinal extract exit
Method, to evade the inspectoral inspection of GMP.The often negligence of management of such method, just becomes to perform practically no function for a long time, laminar flow
Trolley is only just enabled when inspector comes, the medicinal extract quality safety that can not really guarantee.
Although above two method all meets GMP requirement simultaneously, suffer from the drawback that
1) need to be arranged in clean area due to receiving cream process, keep workshop arrangement limited, inspissator receives cream pipeline and wears floor, pipeline compared with
Long, there is risk in pipeline cleaning, medicinal extract residual；
2) the general storage temperature of medicinal extract is between 2 ~ 10 DEG C, in order to store extra medicinal extract, generally requires to add dedicated freezer；
3) medicinal extract is such as long-term places, and microorganism is easily exceeded, generally requires to increase sterilization process before storage, need to add sterilizing and set
It is standby.
Summary of the invention
In order to solve the problems in the existing technology, the present invention provides a kind of storages of structurally reasonable traditional Chinese medicine extraction medicinal extract
Deposit tank and its application method；It is intended to both be able to satisfy the requirement of GMP specification, while reducing unnecessary storage transhipment process, reduce
Production cost saves the production energy, preferably creates profit for enterprise.
Technical scheme is as follows:
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that including medicinal extract tank liner, be arranged in it is upper at the top of medicinal extract tank liner
End socket, the lower head that medicinal extract tank liner at the bottom is set and it is arranged at the top of upper cover and for the medicinal extract in medicinal extract tank liner
The stirring system being stirred, the medicinal extract tank liner outside are equipped with medicinal extract tank collet, and the upper cover is equipped with inlet, institute
Lower head bottom is stated equipped with discharge port, the medicinal extract tank collet upper end is suitable for reading equipped with collet, and bottom is equipped with mouth under collet.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that the stirring system includes that motor and motor pass
The speed reducer of dynamic connection and the anchor formula agitating paddle connecting with speed reducer drive, the motor use fire-proof motor, the speed reducer
Using worm and gear horizontal type structure.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that the upper cover is equipped with visor observation panel, puts
It eats dishes without rice or wine, manhole, Butterworth Hatch, pressure gauge connection and interface of the level gauge, the medicinal extract tank liner are equipped with thermometer boss, the view
Sem observation mouth, drain, manhole, cleaning sprays ball and interface of the level gauge is all made of flange or ready-packaged joint is connected to upper cover
On.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that the medicinal extract tank liner operating pressure be-
0.1MPa~0.3MPa, the medicinal extract tank collet operating pressure are normal pressure 0.1MPa~0.4MPa, the medicinal extract tank liner work
Temperature is 7 DEG C~121 DEG C, the medicinal extract tank collet operating temperature are as follows: 5 DEG C~151 DEG C.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that the medicinal extract tank liner is equipped with for its peace
The vertical trunnion of dress.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that be furnished with LED spotlight on the visor observation panel.
A kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that cleaning spray ball is equipped on the Butterworth Hatch.
A kind of application method of the traditional Chinese medicine extraction medicinal extract holding vessel, which comprises the steps of:
1) receive cream process: the medicinal extract after concentrated is delivered into medicinal extract tank liner by inlet, and medicinal extract tank collet leads to refrigerant
Water, chilled water mouth under collet are passed through in medicinal extract tank collet, and from collet outflow suitable for reading, are exchanged heat by medicinal extract tank collet,
Medicinal extract in medicinal extract tank liner is cooled to 5 DEG C hereinafter, the temperature is kept to store, anchor formula agitating paddle carries out in cooling procedure
Stirring, keeps temperature uniform；
2) sterilization process: emptying chilled water, be passed through steam, keep the temperature 30-60 minutes after being warming up to 100-121 DEG C in medicinal extract collet,
Heat sterilization process is carried out, anchor formula agitating paddle is stirred in temperature-rise period, keeps temperature uniform, passes through pressure during sterilization process
Power table, thermometer monitor pressure and temp in real time, to judge whether to meet process set value；
3) melt cream process: in medicinal extract collet after emptying chilled water, being passed through hot water heating to 25 DEG C -30 DEG C, and when heating passes through anchor formula
Agitating paddle is stirred, and keeps heating temperature uniform；After heating, pressure in medicinal extract tank liner 1 by drain discharge to
Normal pressure is transported through after being then emitted into storage vat by discharge port；
4) cleaning process: completing the medicinal extract tank liner 1 of discharging, need to carry out cleaning process, is successively passed through hot water, originally in Butterworth Hatch
Water or purified water complete the cleaning to medicinal extract tank liner by cleaning spray ball.
The beneficial effects of the present invention are:
1) medicinal extract being conveyed using pipeline liquid injecting device, final discharge port docks insulation barrel using sealed valve, without open operating process, because
This medicinal extract tank arrangement can be not arranged in clean area, reduce workshop and receive cream purifying area arrangement；
2) medicinal extract storage directly completed in medicinal extract tank, medicinal extract tank by collet be passed through cooling water holding tank in temperature on 5 DEG C of left sides
The right side reduces the configuration needs of workshop freezer；
3) when needing medicinal extract to discharge, hot water completion melt cream process is passed through by collet, work is passed through by collet if you need to sterilize
Industry steam, heating complete sterilization process after a certain period of time, have saved the equipment investment of melt cream equipment and sterilizing installation；
4) on-line cleaning can be achieved after medicinal extract discharging, prevents cross contamination, meet the requirement of GMP cleaning verifying；
5) big using the receipts cream process investment after traditional Chinese medicine extraction medicinal extract holding vessel, solved in traditional Chinese medicine extraction, it can not go to
The puzzlement of position, and greatly change the process equipment selection that Chinese medicine receives cream process, increase a variety of choosings for extracting the workshop conceptual level
It selects, keeps workshop arrangement more economical practical.
Detailed description of the invention
Fig. 1 is overall structure diagram of the invention；
Fig. 2 is overlooking structure diagram of the present invention；
In figure: 1- medicinal extract tank liner, 2- medicinal extract tank collet, 3- stirring system, 4- upper cover, 5- lower head, 6- inlet, 7- view
Sem observation mouth, 8- drain, 9- manhole, 10- Butterworth Hatch, 11- thermometer boss, 12- pressure gauge connection, 13- interface of the level gauge,
14- discharge port, 16- collet is suitable for reading, mouth under 17- collet, 18- anchor formula agitating paddle, 19- motor, 20- speed reducer, the vertical branch of 21-
Ear.
Specific embodiment
Below in conjunction with Figure of description, the invention will be further described.
As shown in Figs. 1-2, a kind of traditional Chinese medicine extraction medicinal extract holding vessel, including medicinal extract tank liner 1, medicinal extract tank collet 2, stirring system
System 3, upper cover 4, lower head 5, inlet 6, visor observation panel 7, drain 8, manhole 9, Butterworth Hatch 10, thermometer boss 11,
Pressure gauge connection 12, interface of the level gauge 13, discharge port 14, collet be suitable for reading 16, mouth 17 under collet, anchor formula agitating paddle 18, motor 19,
Speed reducer 20 and vertical trunnion 21.
The holding vessel be it is a kind of can be used in medicinal extract storage, sterilizing, melt cream Chinese medical concrete special container, Chinese medicine can be met
Receipts cream, sterilizing, the melt cream, cleaning process of medicinal extract, and meet GMP laws and regulations requirement.It include medicinal extract tank liner 1, medicinal extract tank collet 2
And stirring system 3.
The upper cover 4 at 1 top of medicinal extract tank liner, the lower head 5 that 1 bottom of medicinal extract tank liner is arranged in, upper cover 4 are equipped with
Visor observation panel 7, drain 8, manhole 9, cleaning spray ball 10, pressure gauge connection 12 and interface of the level gauge 13, medicinal extract tank liner 1
It is equipped with thermometer boss 11, visor observation panel 7, drain 8, manhole 9, Butterworth Hatch 10 and interface of the level gauge 13 are all made of flange
Or ready-packaged joint is connected on upper cover 4；1 operating pressure of medicinal extract tank liner is -0.1MPa~0.3MPa, 1 work of medicinal extract tank liner
Making temperature is 7 DEG C~121 DEG C.
Medicinal extract tank collet 2 is equipped on the outside of medicinal extract tank liner 1, upper cover 4 is equipped with inlet 6, and 5 bottom of lower head is equipped with
Material mouth 14,2 upper end of medicinal extract tank collet are equipped with collet suitable for reading 16, and bottom is equipped with mouth 17 under collet.The medicinal extract tank collet 2 is equipped with
Mouth 17 under collet suitable for reading 16 and collet, can the public medium such as external cooling water, hot water, steam, compressed air.Medicinal extract tank collet 2
Operating pressure is normal pressure 0.1MPa~0.4MPa, 2 operating temperature of medicinal extract tank collet are as follows: 5 DEG C~151 DEG C.
Stirring system includes motor 19, the speed reducer 20 being sequentially connected with motor 19 and the anchor being sequentially connected with speed reducer 20
Formula agitating paddle 18, the motor 19 use fire-proof motor, and the speed reducer 20 uses worm and gear horizontal type structure.Stirring system 3,
It should be top dress anchor formula agitating paddle 18 to install, speed of agitator is about 20rpm, and the paddle bottom amount of radially wobbling is less than 1mm.
Medicinal extract tank liner 1 is equipped with the vertical trunnion 21 for its installation.
Visor observation panel 7 need to match light-focusing type visor LED spotlight, have antifog, explosion-proof, waterproof, resistance to 100 DEG C or more high temperature,
Illuminance is not less than 2000 lux.
The metal of equipment and material contact component selects the stainless steel making of SUS304, and non-metallic component meets medicinal requirements,
Be all made of it is nontoxic, without fall off, the material without absorption.Equipment surface and all fasteners are all stainless steel material, equipment and attachment
Outer surface is wire drawing process；Inner surface carries out electrobrightening processing, surface roughness Ra≤0.2 μm.
Receive cream process: the medicinal extract after concentrated delivers into medicinal extract tank liner 1 by inlet 6, and medicinal extract tank collet 2 leads to cold
Matchmaker's water, chilled water mouth 17 under collet are passed through medicinal extract tank collet 2, from collet 16 outflow suitable for reading, by jacket for heat exchange, by holding vessel
Interior medical fluid is cooled to 5 DEG C hereinafter, the temperature is kept to be stored, and anchor formula agitating paddle 18 is stirred in cooling procedure, makes temperature
Uniformly.Sterilization process: after being connected to discharging instruction, medicinal extract collet 2 empties chilled water, is passed through steam, keeps the temperature after being warming up to 121 DEG C
30 minutes, heat sterilization process is carried out, anchor formula agitating paddle 18 is stirred in temperature-rise period, keeps temperature uniform.Sterilization process mistake
Pressure and temp is monitored in real time by pressure gauge, thermometer in journey, to judge whether to meet process set value.
Melt cream process: according to technique, the medicinal extract for not needing partially to sterilize can skip sterilization process, 2 row of medicinal extract collet
After empty chilled water, it is passed through hot water heating to 25 DEG C, when heating is stirred by anchor formula agitating paddle 18, keeps heating temperature uniform.
After heating, medicinal extract pressure inside the tank is discharged by drain 8 to normal pressure, is turned after being then emitted into IBC barrels by discharge port 14
It is transported to other workshops.
Cleaning process: completing the medicinal extract tank of discharging, need to carry out cleaning process, is successively passed through hot water, originally in Butterworth Hatch 10
Water, purified water complete the cleaning to medicinal extract tank by cleaning spray ball.
Claims (8)
1. a kind of traditional Chinese medicine extraction medicinal extract holding vessel, which is characterized in that including medicinal extract tank liner (1), be arranged in medicinal extract tank liner (1)
The upper cover (4) at top, setting at the top of upper cover (4) and are used in the lower head (5) of medicinal extract tank liner (1) bottom and setting
To the stirring system (3) that the medicinal extract in medicinal extract tank liner (1) is stirred, medicinal extract tank is equipped on the outside of the medicinal extract tank liner (1)
Collet (2), the upper cover (4) are equipped with inlet (6), and lower head (5) bottom is equipped with discharge port (14), the medicinal extract
Tank collet (2) upper end is (16) suitable for reading equipped with collet, and bottom is equipped with mouth (17) under collet.
2. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 1, which is characterized in that the stirring system includes electricity
Machine (19), the anchor formula agitating paddle (18) with the speed reducer (20) of motor (19) transmission connection and with speed reducer (20) transmission connection,
The motor (19) uses fire-proof motor, and the speed reducer (20) uses worm and gear horizontal type structure.
3. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 1, which is characterized in that set on the upper cover (4)
There are visor observation panel (7), drain (8), manhole (9), cleaning spray ball (10), pressure gauge connection (12) and interface of the level gauge
(13), the medicinal extract tank liner be equipped with thermometer boss (11), the visor observation panel (7), drain (8), manhole (9),
Butterworth Hatch (10) and interface of the level gauge (13) are all made of flange or ready-packaged joint is connected on upper cover (4).
4. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 1, which is characterized in that the medicinal extract tank liner (1)
Operating pressure is -0.1MPa~0.3MPa, and medicinal extract tank collet (2) operating pressure is normal pressure 0.1MPa~0.4MPa, described
Medicinal extract tank liner (1) operating temperature is 7 DEG C~121 DEG C, medicinal extract tank collet (2) operating temperature are as follows: 5 DEG C~151 DEG C.
5. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 1, which is characterized in that the medicinal extract tank liner (1)
It is equipped with the vertical trunnion (21) for its installation.
6. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 3, which is characterized in that the visor observation panel (7)
It is upper to be furnished with LED spotlight.
7. a kind of traditional Chinese medicine extraction medicinal extract holding vessel according to claim 3, which is characterized in that on the Butterworth Hatch (10)
Ball is sprayed equipped with cleaning.
8. the application method of -7 any a kind of traditional Chinese medicine extraction medicinal extract holding vessels according to claim 1, which is characterized in that packet
Include following steps:
1) receive cream process: the medicinal extract after concentrated is delivered into medicinal extract tank liner (1) by inlet (6), medicinal extract tank collet
(2) lead to chilled water, chilled water mouth (17) under collet is passed through in medicinal extract tank collet (2), and is flowed out from collet (16) suitable for reading, is passed through
Medicinal extract tank collet (2) exchanges heat, and the medicinal extract in medicinal extract tank liner (1) is cooled to 5 DEG C hereinafter, the temperature is kept to store up
It deposits, anchor formula agitating paddle (18) is stirred in cooling procedure, keeps temperature uniform；
2) sterilization process: emptying chilled water, be passed through steam in medicinal extract collet (2), 30-60 points are kept the temperature after being warming up to 100-121 DEG C
Clock carries out heat sterilization process, and anchor formula agitating paddle (18) is stirred in temperature-rise period, keeps temperature uniform, sterilization process process
In pressure and temp is monitored in real time by pressure gauge, thermometer；
3) melt cream process: in medicinal extract collet (2) after emptying chilled water, being passed through hot water heating to 25 DEG C -30 DEG C, and when heating passes through anchor
Formula agitating paddle (18) is stirred, and keeps heating temperature uniform；After heating, the pressure in medicinal extract tank liner 1 passes through drain
(8) release is transported through after being then emitted into storage vat by discharge port (14) to normal pressure；
4) cleaning process: complete discharging medicinal extract tank liner 1, cleaning process need to be carried out, Butterworth Hatch (10) be successively passed through hot water,
Tap water or purified water complete the cleaning to medicinal extract tank liner (1) by cleaning spray ball.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811251886.1A CN109398980A (en) | 2018-10-25 | 2018-10-25 | A kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811251886.1A CN109398980A (en) | 2018-10-25 | 2018-10-25 | A kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109398980A true CN109398980A (en) | 2019-03-01 |
Family
ID=65469195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811251886.1A Pending CN109398980A (en) | 2018-10-25 | 2018-10-25 | A kind of traditional Chinese medicine extraction medicinal extract holding vessel and its application method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109398980A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110406825A (en) * | 2019-07-26 | 2019-11-05 | 商丘市安俪嘉建材科技有限公司 | Holding vessel is used in a kind of production of exterior wall latex paint |
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|---|---|---|---|---|
| CN203493950U (en) * | 2013-09-28 | 2014-03-26 | 大理药业股份有限公司 | Sterilization tank for sterilization of astragalus injection intermediate goods |
| CN204395541U (en) * | 2015-01-07 | 2015-06-17 | 温州市龙强乳品机械厂 | A kind of alcohol precipitation tank |
| CN105251237A (en) * | 2015-11-12 | 2016-01-20 | 河北智同生物制药有限公司 | Vertical type tubulation heat exchange extraction tank and application thereof |
| CN206746027U (en) * | 2017-01-23 | 2017-12-15 | 南京企鸿制药设备有限公司 | Frame type stirring Agitation Tank |
| CN209684466U (en) * | 2018-10-25 | 2019-11-26 | 浙江省天正设计工程有限公司 | A kind of traditional Chinese medicine extraction medicinal extract holding vessel |
-
2018
- 2018-10-25 CN CN201811251886.1A patent/CN109398980A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203493950U (en) * | 2013-09-28 | 2014-03-26 | 大理药业股份有限公司 | Sterilization tank for sterilization of astragalus injection intermediate goods |
| CN204395541U (en) * | 2015-01-07 | 2015-06-17 | 温州市龙强乳品机械厂 | A kind of alcohol precipitation tank |
| CN105251237A (en) * | 2015-11-12 | 2016-01-20 | 河北智同生物制药有限公司 | Vertical type tubulation heat exchange extraction tank and application thereof |
| CN206746027U (en) * | 2017-01-23 | 2017-12-15 | 南京企鸿制药设备有限公司 | Frame type stirring Agitation Tank |
| CN209684466U (en) * | 2018-10-25 | 2019-11-26 | 浙江省天正设计工程有限公司 | A kind of traditional Chinese medicine extraction medicinal extract holding vessel |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110406825A (en) * | 2019-07-26 | 2019-11-05 | 商丘市安俪嘉建材科技有限公司 | Holding vessel is used in a kind of production of exterior wall latex paint |
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