CN109394652B - Repairing emulsion for removing whelks and acnes and preparation method thereof - Google Patents

Repairing emulsion for removing whelks and acnes and preparation method thereof Download PDF

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Publication number
CN109394652B
CN109394652B CN201811630580.7A CN201811630580A CN109394652B CN 109394652 B CN109394652 B CN 109394652B CN 201811630580 A CN201811630580 A CN 201811630580A CN 109394652 B CN109394652 B CN 109394652B
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traditional chinese
chinese medicine
medicine extract
whelks
acnes
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CN109394652A (en
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李玉萍
戴好富
蔡彩虹
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Hainan Shiboli Biotechnology Co ltd
Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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Hainan Shiboli Biotechnology Co ltd
Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

Abstract

The invention discloses a repair milk for removing whelks and acnes and a preparation method thereof, wherein the repair milk comprises the following components in parts by weight: 3-6% of traditional Chinese medicine extract, 5-40% of oil phase raw material, 0.05-10% of skin care product additive, 0.05-1% of nutritional additive and 50-91.9% of deionized water. Wherein the traditional Chinese medicine extract is dendrobium, kohlrabi, caltrop, ligusticum wallichii, fructus momordicae and motherwort fruit, and the weight ratio is 20-40: 15-30: 10-20: 10-20: 10-20: 5-10. The repair cream has good repair effect on facial problems such as whelks, acnes and the like, and the whelks and the acnes can be cured within 8 weeks after the repair cream is used.

Description

Repairing emulsion for removing whelks and acnes and preparation method thereof
Technical Field
The invention relates to the field of cosmetics, in particular to a repair cream for removing whelks and acnes and a preparation method thereof.
Background
Acne is a chronic inflammation of hair follicles and sebaceous glands, and mainly occurs in the greasy areas of the face, chest and back, etc. Self-limiting, skin lesions are in multiple forms. Such as acne, papules, pustules, nodules. Seborrhea is often accompanied, and most of the seborrhea is cured or relieved after puberty. In the past, acne is considered to be sebaceous gland diseases, substantially damages hair follicles, sebaceous glands and epidermis, belongs to the field of lung wind acne in traditional Chinese medicine, and in the traditional Chinese medicine, aiming at the lung wind acne, the traditional Chinese medicine considers that the acne can be treated by methods of dispelling wind and relieving heat, clearing heat and purging fire, promoting blood circulation and removing blood stasis and the like.
Dendrobe is slightly cold in nature and sweet in taste, enters stomach and kidney meridians, can nourish yin, promote the production of body fluid, clear lung-heat and stomach deficiency-heat, and is used for clearing and nourishing heat in ancient times. The book of formation is listed as the head of the 'Chinese Jiuda Mesona' from the classic Daojia medicine 'Daozha' more than one thousand years ago. The herba Cibotii is bitter in taste and cold in nature, and has effects of clearing heat, cooling blood, promoting urination, calming liver, and improving eyesight. The caltrop is bitter and pungent in taste, enters liver meridian, and has the effects of calming liver, resolving depression, promoting blood circulation, dispelling wind, improving eyesight and relieving itching. The rhizoma ligustici wallichii is pungent in flavor and warm in nature, enters liver, gallbladder and pericardium channels, and has the effects of activating blood circulation to remove stasis, promoting qi circulation and relieving depression. Du Ruo has the effects of regulating qi, relieving pain, dispelling wind and relieving swelling. The motherwort fruit is sweet and pungent in flavor and slightly cold in nature, enters liver meridian, and has the effects of activating blood and regulating menstruation.
Disclosure of Invention
Therefore, the invention aims to provide a repair milk for treating whelk and acne and a preparation method thereof.
The technical scheme of the invention is realized as follows:
a repair cream for removing whelk and acne comprises the following components by weight: 3-6% of traditional Chinese medicine extract, 5-40% of oil phase raw material, 0.05-10% of skin care product additive, 0.05-1% of nutritional additive and 50-91.9% of deionized water.
Further, the traditional Chinese medicine extract comprises: herba Dendrobii, herba Setariae viridis, fructus Tribuli, rhizoma Ligustici Chuanxiong, fructus Leonuri and fructus Dolichoris extract; wherein the weight ratio of the dendrobium to the green dog liver, the caltrop to the ligusticum wallichii to the duckweed to the motherwort fruit is 20-40: 15-30: 10-20: 10-20: 10-20: 5-10.
Further, the oil phase raw materials comprise white oil, volatile cyclic silicone oil and glycerol.
Further, the skin care product additive comprises cetyl alcohol, glyceryl stearate, disodium polyethoxylated lauryl ether citrate succinate, PEG-2OO reduced glyceryl palmitate, PEG-7 glyceryl cocoate and preservative.
A preparation method of a repair emulsion for removing whelks and acnes comprises the following steps:
step 1: cleaning fresh herba Dendrobii, fresh herba Setariae viridis, fructus Tribuli, rhizoma Ligustici Chuanxiong, fructus Leonuri and fructus Piperis Longi, oven drying, and cutting into segments; according to the weight ratio of 20-40: 15-30: 10-20: 10-20: 10-20: 10-20 mixing;
step 2: adding 15-20 times of ethanol-deionized water into the mixture, and leaching for 4-5 times, wherein the leaching time is 5-10h each time;
and step 3: collecting the leaching liquor obtained in the step 2, and concentrating;
and 4, step 4: heating oil phase raw materials to 70-90 deg.C under oxygen-isolated condition, adding deionized water, skin care product additive and nutritional additive, homogenizing, emulsifying, stirring, cooling to 45-60 deg.C, adding Chinese medicinal extract, stirring, and cooling to room temperature;
and 5: and (4) sterilizing the emulsion obtained in the step (4), inspecting the quality and packaging.
Compared with the prior art, the invention has the beneficial effects that:
1) the traditional Chinese medicine composition adopts six traditional Chinese medicines of dendrobium, doggie, tribulus terrestris, ligusticum wallichii, fructus psoraleae and motherwort fruit, has a reasonable formula, and has a beneficial effect on treating whelk and acne.
2) The invention adopts hyaluronic acid, vitamin A and collagen, wherein the hyaluronic acid has the effects of tenderizing and smoothing skin, removing wrinkles and the like, and promotes transdermal absorption of other nutrient substances while preserving moisture; vitamin a can prevent abnormal keratinization of epidermal cells.
3) The preparation method is simple in preparation process, stable in product quality and applicable to large-scale production.
Detailed Description
For clear and complete description of the technical solutions in the present invention, it is obvious that the inventor combines the embodiments to describe, but the following embodiments describe only some embodiments of the present invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
A repair cream for removing whelk and acne comprises the following components by weight: 3-6% of traditional Chinese medicine extract, 5-40% of oil phase raw material, 0.05-10% of skin care product additive, 0.05-1% of nutritional additive and 50-91.9% of deionized water.
Further, the traditional Chinese medicine extract comprises: herba Dendrobii, herba Setariae viridis, fructus Tribuli, rhizoma Ligustici Chuanxiong, fructus Leonuri and fructus Dolichoris extract; wherein the weight ratio of the dendrobium to the green dog liver, the caltrop to the ligusticum wallichii to the duckweed to the motherwort fruit is 20-40: 15-30: 10-20: 10-20: 10-20: 5-10.
Further, the oil phase raw materials comprise white oil, volatile cyclic silicone oil and glycerol.
Further, the skin care product additive comprises cetyl alcohol, glyceryl stearate, disodium polyethoxylated lauryl ether citrate succinate, PEG-2OO reduced glyceryl palmitate, PEG-7 glyceryl cocoate and preservative.
Extracting the traditional Chinese medicine composition:
cleaning fresh herba Dendrobii, fresh herba Setariae viridis, fructus Tribuli, rhizoma Ligustici Chuanxiong, fructus Leonuri and fructus Piperis Longi, oven drying, and cutting into segments; mixing the raw materials according to the proportion of examples 1-4 and comparative examples 1-4 to obtain a traditional Chinese medicine mixture; adding 15-20 times of ethanol-deionized water for leaching for 4-5 times, wherein the leaching time is 5-10h each time; collecting the obtained leaching solution, and concentrating.
Table 1: the dosage ratios of the traditional Chinese medicine compositions in examples 1-4 and comparative examples 1-5 are as follows:
Figure GDA0003300857820000031
selecting 30 severe volunteers with acne, diluting the above Chinese medicinal extract with commercially available common emulsion to 5 wt%, coating on affected part, and using for a period of time. And taking a picture under the same light, and comparing the conditions before and after use. The results are shown in Table 2:
table 2, examples 1-4, comparative examples 1-5 use cases:
Figure GDA0003300857820000032
Figure GDA0003300857820000041
in combination with the examples 1-4 and the comparative example 5, the traditional Chinese medicine composition obtained according to the proportion provided by the invention has good healing effect on whelks and acnes, and the traditional Chinese medicine composition which exceeds the proportion provided by the invention has certain effect on treating the whelks and the acnes, but the effect is reduced.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (1)

1. A repair cream for removing whelk and acne is characterized by comprising 3 to 6 percent of traditional Chinese medicine extract by weight; the traditional Chinese medicine extract comprises the following components: the weight ratio of the extracts of dendrobium, kojic vegetable, tribulus terrestris, ligusticum wallichii, duckweed and motherwort fruit is 20-40: 15-30: 10-20: 10-20: 10-20: 5-10;
the traditional Chinese medicine extract is prepared by the following method:
step 1: cleaning fresh herba Dendrobii, fresh herba Setariae viridis, fructus Tribuli, rhizoma Ligustici Chuanxiong, fructus Leonuri and fructus Piperis Longi, oven drying, cutting into segments, and mixing;
step 2: adding 15-20 times of ethanol-deionized water into the mixture, and leaching for 4-5 times, wherein the leaching time is 5-10h each time;
and step 3: collecting the leaching liquor obtained in the step 2, and concentrating to obtain the traditional Chinese medicine extract.
CN201811630580.7A 2018-12-29 2018-12-29 Repairing emulsion for removing whelks and acnes and preparation method thereof Active CN109394652B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102648968A (en) * 2011-02-26 2012-08-29 晏素琼 External traditional Chinese medicine composition for eye health
CN105999062A (en) * 2016-05-31 2016-10-12 安徽皖斛堂生物科技有限公司 Moisture-preserving acne-curing dendrobium officinale extract medicated soap and preparation method thereof
KR101725969B1 (en) * 2013-12-31 2017-04-11 주식회사 풀무원 A cosmetic composition effective for skin whitening comprising multiple herbal extracts
CN107875089A (en) * 2017-11-22 2018-04-06 天津市蓝宝石化妆品有限公司 A kind of skin care item containing dendrobium candidum and its preparation method and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050108045A1 (en) * 2003-11-17 2005-05-19 Jiao Gong Method of network hospital of reclassification of diseases that have been made a diagnosis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102648968A (en) * 2011-02-26 2012-08-29 晏素琼 External traditional Chinese medicine composition for eye health
KR101725969B1 (en) * 2013-12-31 2017-04-11 주식회사 풀무원 A cosmetic composition effective for skin whitening comprising multiple herbal extracts
CN105999062A (en) * 2016-05-31 2016-10-12 安徽皖斛堂生物科技有限公司 Moisture-preserving acne-curing dendrobium officinale extract medicated soap and preparation method thereof
CN107875089A (en) * 2017-11-22 2018-04-06 天津市蓝宝石化妆品有限公司 A kind of skin care item containing dendrobium candidum and its preparation method and application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中西医结合治疗痤疮的疗效观察;赵斌等;《中国麻风皮肤病杂志》(第09期);第741页 *

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