CN109394193A - A kind of method of ambulatory blood pressure logger real-time clock calibration - Google Patents

A kind of method of ambulatory blood pressure logger real-time clock calibration Download PDF

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Publication number
CN109394193A
CN109394193A CN201811422848.8A CN201811422848A CN109394193A CN 109394193 A CN109394193 A CN 109394193A CN 201811422848 A CN201811422848 A CN 201811422848A CN 109394193 A CN109394193 A CN 109394193A
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calibration
time
logger
real
clock
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CN201811422848.8A
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CN109394193B (en
Inventor
吕军
闫佩玉
王子南
刘雪芬
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CHANCEFINE Co Ltd
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CHANCEFINE Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F1/00Details not covered by groups G06F3/00 - G06F13/00 and G06F21/00
    • G06F1/04Generating or distributing clock signals or signals derived directly therefrom
    • G06F1/14Time supervision arrangements, e.g. real time clock

Abstract

A kind of method of ambulatory blood pressure logger real-time clock calibration, pass through the setting to memory block alignment area, the time of system one calibration error of every operation, it is low level (0) that corresponding calibration areas, which just has high-order (1) variation, when there is bad block in calibration areas, as long as also high-order variation is low level after bad block, mean that system is also being run, it is more than calibration failure after the calibration time limit between when running, time limit mark also can be low level (0) by high-order (1) variation;The present invention solves logger due to complex electromagnetic environment or the caused real-time clock deviation of data transmission interface interference, also evaded due to data bit read it is improper caused by real-time clock calibration error;Meanwhile but also the accuracy and reliability of ambulatory blood pressure logger real-time clock is greatly improved, also avoid as real-time clock is incorrect and caused by measurement process disorder the phenomenon that.

Description

A kind of method of ambulatory blood pressure logger real-time clock calibration
Technical field
The present invention relates to Medical Instruments technical field, in particular to a kind of side of ambulatory blood pressure logger real-time clock calibration Method.
Technical background
Blood pressure is the weight for reflecting the physiological parameters such as cardiac pumping function, vascular resistence, viscosity of blood and whole body blood volume Index is wanted, there is important diagnostic value.With the development of electronic technology, computer and signal processing, automatic noninvasive blood Pressure monitoring technology is clinically widely applied.Blood pressure, which has, significantly changes over time characteristic, in the list that clinic carries out The fluctuation and the situation under active state that secondary or few blood pressure measurement cannot reliably reflect blood pressure.Ambulatory blood pressure measurement is 24 In hour under automatic discontinuous property Timing measurement daily life state blood pressure a kind of diagnostic techniques.It is examined since ambulatory blood pressure overcomes Institute's blood pressure measurement number is less, the limitation of the error of observation and White coat effect etc., can objectively reflect the real standard of blood pressure With fluctuation situation, therefore makes a definite diagnosis in clinical doubtful hypertensive patient, judge " white coat hypertension " and resistant hypertension, evaluate The curative effect of drug for hypertension and guiding treatment etc. are more and more widely used.
Ambulatory blood pressure in clinical application, needs to set the measurement frequency in different time periods in a measurement period Fixed, then equipment could carry out blood pressure data monitoring and record to patient according to the preset work frequency.This requires that conduct The ambulatory blood pressure logger of acquisition equipment will have very accurate and reliable Real Time Clock System, establish in such system base On plinth, logger can accurately and reliably work according to the set work frequency, without there is the phenomenon that measurement process disorder.
Ambulatory blood pressure logger has been generally integrated real-time timepiece chip.Real-time timepiece chip is in daily life using the most One of extensive consumer electronics product.It provides accurate real-time time for people, or provides accurately for electronic system Time reference.
However in the actual use environment, user's discovery is when using ambulatory blood pressure logger record data, real-time clock The environment on periphery or the transmission of data can all have an impact the real-time clock of logger.When logger is in record data When state, the electromagnetic environment on real-time clock periphery will become more complicated, generate partially so as to cause the real-time clock of logger Difference;When logger is in the state of transmission data, since the coffret of data is in the moment of connection host computer, level occurs Variation, this variation can to real-time clock generate interference so that transmission data at the beginning of and transmission time generate deviation or Mistake.
The appearance of problems above directly results in the confusion and not confirmability of measurement process, how to avoid such existing The appearance of elephant becomes the important indicator of ambulatory blood pressure logger product reliability;The importance of real-time clock and its unreliability Contradiction to solve this technical application problem extremely urgent.
Summary of the invention
In order to overcome the contradiction between real-time clock importance and its unreliability, the object of the present invention is to provide one The method of kind ambulatory blood pressure logger real-time clock calibration solves logger since complex electromagnetic environment or data transmission connect Dry disturbs caused real-time clock deviation, evaded due to data bit read it is improper caused by real-time clock calibration mistake Difference;When logger is restarted or transmits data, logger carries out the calibration of real-time clock, by system clock and real-time clock Time compares, if the two error is more than defined error, needs to adjust the time of system clock to ensure that logger is remembered Record corresponding with the time accuracy and reliability of patient data, avoid as system clock is incorrect and caused by measurement process it is disorderly Random phenomenon.
In order to achieve the above object, the technical solution of the present invention is as follows:
A kind of method of ambulatory blood pressure logger real-time clock calibration, comprising the following steps:
Step 1: the design of real-time clock calibration memory block 101
Real-time clock calibration memory block 101 is divided for 3 parts: timestamp 102, calibration areas 103 and time limit mark 104, 101 size of memory block is designed according to calibration error and calibration time limit.
After logger starting, all data bit in memory block 101 are all in high-order (1), the starting time X X of logger X divides X seconds with the first six byte representation when month X days X, writes in timestamp 102;
Calibration the time limit in, as soon as logger it is every operation calibration error time, calibration areas 103 have a byte by High-order (1) becomes low level (0);Since memory block 101 has bad block or non-readable data bit once in a while, calibration areas 103 makes With multiple data bit, this problem is evaded with the relationship of "or", in 101 reading process of memory block, as long as current read Word, byte value be less than the maximum value of word or byte, mean that system operates normally, effective modification carried out to flag bit;When Runing time is prescribed a time limit when being more than calibration, and time limit mark 104 will become low level (0) from high-order (1), at this point, logger automatically into The function of row real-time clock calibration will fail, and calibration later enters manual calibration mode;
Step 2: the design calibrated under ambulatory blood pressure logger different working condition
1. logger, which is in, continues recording status, after each measurement, measurement interval next time is calculated,
2. logger log-on data is transmitted,
3. logger is in data continuous transmission state, set prover time interval (such as 5 minutes),
The above state (1. 2. 3.) needs to carry out real-time clock calibration to logger, when calibration, starts to remember by timestamp The time of record is added with the period that calibration areas is run, and obtains the time of real-time clock, compares with system clock, if the two Error is more than specification error, then needs to be adjusted system clock, achievees the purpose that real-time clock is calibrated.
4. due to complex electromagnetic environment, logger is restarted automatically into recording status,
5. since coffret is caused logger to be restarted by the interference of electromagnetic compatibility,
4. 5. by soft and hardware house dog, logger can be restarted automatically the above state immediately after crashing, and guarantee that system is normal The reliability of work and calibration function, after logger starting, by time of timestamp start recording and calibration areas operation when Between section be added to obtain the time of real-time clock, compared with system clock, if the two error is more than specification error, adjusts and be System clock achievees the purpose that real-time clock is calibrated.
Beneficial effects of the present invention:
1, it is added to obtain reality with the period that calibration areas (103) are run by the time for starting timestamp (102) record When clock time, compared with system clock, carry out real-time clock calibration, this set not only ensures user using ambulatory blood pressure The system's real-time clock time will not be chaotic when equipment, also improves the precision of system clock, more accurately to obtain patients' blood Information provides safeguard.
2, the one-to-one correspondence that ambulatory blood pressure logger record information and real-time clock greatly improved, ensure that logger In the case where transmission data, the environment such as restarting, accurate patient information and corresponding time still can recorde.
Detailed description of the invention
Fig. 1 is the division of memory block of the invention.
Fig. 2A is the flow diagram in real-time clock calibration areas of the invention;Fig. 2 B is the stream in real-time clock calibration areas Journey illustrates figure.
Fig. 3 is the flow diagram of ambulatory blood pressure logger real-time clock calibration of the invention.
Specific embodiment
The invention will now be described in detail with reference to the accompanying drawings.
A kind of method of ambulatory blood pressure logger real-time clock calibration, referring to Fig. 3, into work shape after logger booting Then state reads real time clock information, and is calibrated.When calibration, real-time clock is compared with system clock, if The two error is more than specification error, then needs to adjust system clock, so that logger works normally, specifically includes the following steps:
Step 1: real-time clock calibrates the design of memory block 101 referring to Fig. 1
Real-time clock calibration memory block 101 is divided for 3 parts: timestamp 102, calibration areas 103 and time limit mark 104, 101 size of memory block is designed according to calibration error and calibration time limit.
After logger starting, all data bit in memory block 101 are all in high-order (1).The starting time X X of logger X divides X seconds with the first six byte representation when month X days X, writes in timestamp 102;
Calibration the time limit in, as soon as logger it is every operation calibration error time, calibration areas 103 have a byte or Person one etc. becomes low level (0) from high-order (1);Since memory block 101 has bad block or non-readable data bit, school once in a while Quasi- area 103 uses multiple data bit, this problem is evaded with the relationship of "or", in 101 reading process of memory block, as long as There are also to the variation of low level (0), mean that system is also being run by high-order (1) after bad block;It is more than the calibration time limit between when running When, time limit mark 104 will become low level (0) from high-order (1), at this point, logger carries out the function of real-time clock calibration automatically It will fail, calibration later enters manual calibration mode;
For example: regulation calibration error 1 minute is calibrated the time limit 30 hours, and 101 length of memory block is then 1807 words Section: X divides X seconds when X X starting time, X month X day of preceding 6 byte representation loggers, writes in timestamp 102;Intermediate calibration areas 103 each byte represents 1 minute;The last byte is calibration time limit mark 104.The big of memory block 101 can to sum up be obtained Small is 6+30x 60+1=1807 byte.
Referring to fig. 2, after logger starts, all data bit in memory block 101 are all in high-order (1), with preceding 6 words Section indicates that X divides X seconds when X X starting time, X month X day of logger, the time of one calibration error of the later every operation of system, phase Corresponding calibration areas 103 will occur by the variation of high-order (1) to low level (0), when the time of logger operation being more than calibration In limited time, time limit mark 104 is also low level (0) by high-order (1) variation, indicates the calibration failure of logger.
For example: all data of memory block 101 are expressed as 0xFF, when the starting of preceding 6 byte representation loggers Between X X month X day X when X divide X seconds;In calibration areas 103, each byte representation one minute, then the every operation of system one minute, calibration The correspondence of area 103 just has a 0xFF is write as 0x00, therefore how many 0x00 in calibration areas 103, means that system is run How many minute, it can be obtained by a time point in this way, this time point compared with system clock, if error exists Within the scope of defined calibration error, then do not have to carry out system clock adjustment, if error is more than prescribed limit, when needing to system Clock is adjusted, so that real-time clock is more accurate, obtained patient data is corresponding with time height.
When there are bad block or non-readable data bit in memory block 101, then the relationship of "or" is used, as long as calibration areas There are also to the variation of low level (0), meant that system is also being run by high-order (1), only run to number thereafter after 101 bad block According to position, all there is no variations, then it represents that system end of run.Such as with one byte representation one minute, in calibration areas (103) Nth byte is run to, all there is no variations for data bit thereafter, and at this moment the runing time of system is (to note: fortune for N minutes The byte number gone is not offered as the runing time of system), the requirement to memory block 101 had not only been reduced in this way, but also improved note Record the accuracy of device calibration.
Step 2: the design calibrated under ambulatory blood pressure logger different working condition
2. recording device and being in and continue recording status, after each measurement, measurement interval next time is calculated,
2. logger log-on data is transmitted,
3. logger is in data continuous transmission state, set prover time interval (such as 5 minutes),
1. 2. 3. the above state needs to carry out real-time clock calibration to logger, when calibration, pass through timestamp start recording Time be added with the period that calibration areas is run, obtain the time of real-time clock, compared with system clock, if the two miss Difference is more than specification error, then needs to be adjusted system clock, achievees the purpose that real-time clock is calibrated.
4. due to complex electromagnetic environment, logger is restarted automatically into recording status,
5. since coffret is caused logger to be restarted by the interference of electromagnetic compatibility,
4. 5. by soft and hardware house dog, logger can be restarted automatically the above state immediately after crashing, and guarantee that system is normal The reliability of work and calibration function.After logger starting, by time of timestamp start recording and calibration areas operation when Between section be added to obtain the time of real-time clock, compared with system clock, if the two error is more than specification error, adjusts and be System clock achievees the purpose that real-time clock is calibrated.
Logger is at work, it is also possible to because the interference of coffret is either because complicated electromagnetic environment, causes Logger crashes, and at this moment the soft and hardware house dog in system then guarantees that system restarts, and carries out real-time clock calibration.Record Device is when continue record, every time after measurement, requires to calculate the time interval measured next time, at this time, it may be necessary to right Real-time clock is calibrated, to guarantee the accuracy of real-time clock.When transmitting data, after log-on data transmission each time, Carry out the calibration of real-time clock.Or logger is when being in continuous transmission data mode, in predetermined time interval, in real time Clock will be calibrated accordingly, so that the error of real-time clock is at the appointed time, it is ensured that at the beginning of transmission data It is accurate with finish time.

Claims (1)

1. a kind of method of ambulatory blood pressure logger real-time clock calibration, which comprises the following steps:
Step 1: the design of real-time clock calibration memory block 101
Real-time clock calibration memory block 101 is divided for 3 parts: timestamp 102, calibration areas 103 and time limit mark 104, according to Calibration error and calibration time limit design 101 size of memory block;
After logger starting, all data bit in memory block 101 are all in high-order (1), month X day starting time X X of logger X divides X seconds with the first six byte representation when X, writes in timestamp 102;
Within the calibration time limit, as soon as the time of the every operation calibration error of logger, calibration areas 103 has a byte by a high position (1) become low level (0);Since memory block 101 has bad block or non-readable data bit once in a while, calibration areas 103 uses more A data bit evades this problem with the relationship of "or", in 101 reading process of memory block, as long as currently reading word, word The value of section is less than the maximum value of word or byte, means that system operates normally, has carried out effective modification to flag bit;When running Between prescribe a time limit when being more than calibration, time limit mark 104 will become low level (0) from high-order (1), at this point, logger carries out in real time automatically The function of clock alignment will fail, and calibration later enters manual calibration mode;
Step 2: the design calibrated under ambulatory blood pressure logger different working condition
1. logger, which is in, continues recording status, after each measurement, measurement interval next time is calculated,
2. logger log-on data is transmitted,
3. logger is in data continuous transmission state, prover time interval is set,
The above state (1. 2. 3.) needs to carry out real-time clock calibration to logger, when calibration, passes through timestamp start recording Time is added with the period that calibration areas is run, and obtains the time of real-time clock, compares with system clock, if the two error It more than specification error, then needs to be adjusted system clock, achievees the purpose that real-time clock is calibrated;
4. due to complex electromagnetic environment, logger is restarted automatically into recording status,
5. since coffret is caused logger to be restarted by the interference of electromagnetic compatibility,
4. 5. by soft and hardware house dog, logger can be restarted automatically the above state immediately after crashing, and guarantee system worked well With the reliability of calibration function, after logger starting, pass through the period of the time of timestamp start recording and calibration areas operation Addition obtains the time of real-time clock, compares with system clock, if the two error is more than specification error, when adjusting system Clock achievees the purpose that real-time clock is calibrated.
CN201811422848.8A 2018-11-27 2018-11-27 Method for calibrating real-time clock of dynamic blood pressure recorder Active CN109394193B (en)

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