CN109381559A - One group for treating the Chinese medicine of rheumatic arthritis - Google Patents
One group for treating the Chinese medicine of rheumatic arthritis Download PDFInfo
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- CN109381559A CN109381559A CN201710688812.3A CN201710688812A CN109381559A CN 109381559 A CN109381559 A CN 109381559A CN 201710688812 A CN201710688812 A CN 201710688812A CN 109381559 A CN109381559 A CN 109381559A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
Abstract
The invention discloses one group for treating the Chinese medicine of rheumatic arthritis, to solve the problems, such as that it is arthritic that current drug is unable to radical cure of rheumatic.It includes the substance of following parts by weight: excrementum pteropi 10-20g, fructus lycii 6-12g, Radix Salviae Miltiorrhizae 6-12g, radix paeoniae rubra 3-9g, rhizome of chuanxiong 5-15g, monkshood 5-15g, peach kernel 5-15g, Radix Angelicae Sinensis 3-9g, Radix Glycyrrhizae 3-9g.The advantage of the invention is that used Chinese medicine is without side-effects, safe and reliable, curative for effect, quick, cure rate is high.
Description
Technical field
The invention belongs to field of medicaments, and in particular to one group for treating the Chinese medicine of rheumatic arthritis.
Background technique
Rheumatic arthritis is a kind of common acute or chronic connective tissue inflammation.Rheumatic arthritis broadly should
Including rheumatoid arthritis, recurrent exerbation and heart can be involved.Belong to allergic disease, be rheumatic fever main performance it
One, mostly with febris acuta and arthralgia onset.Rheumatic arthritis is performance of the rheumatic fever in joint, and classical symptom is trip
The property walked, multiple large joint are scorching, common to be transferred to another joint by a joint, and lesion locally presents red, swollen, scorching hot, acute
Bitterly, some patients also have several joints while falling ill.Atypical patient only has arthralgia and shows without other inflammation, non-steroid
Body anti-inflammatory drugs effect is obvious, and acute inflammation generally subsided in 2~4 weeks, does not stay sequelae, but normal recurrent exerbation.Patient Chang You
Joint and muscle it is migrans it is miserable, rewrite, the symptoms such as pain.
The cause of disease of rheumatic arthritis is not yet completely understood.According to symptom, epidemiology and immune analysis, it is believed that with people
Body hemolytic streptococcal infection is closely related, notices that virus infection and this disease also have certain relationship at present.Rheumatic arthritis
Principle of reatment be early diagnosis and as early as possible rationally, drug combination.Common antirheumatic object have as follows non-steroidal anti-inflammatory drugs,
Slow effect antirheumatic drug, cell toxicity medicament, cortex hormone of aadrenaline, but these drugs are unable to radical cure of rheumatic arthritis mostly.
Surgical treatment and bone-marrow transplantation clinically can also be used, but this method wound is larger, and the treatment later period can stay scar, to disease
The body and mind of people causes greatly to negatively affect.On the market there are also the Chinese medicine for the treatment of acute mastitis, although these medicines have one
Fixed curative effect, big but there is doses, the time is long and is unable to the arthritic problem of radical cure of rheumatic.
Summary of the invention
It, cannot with the drug for solving current the object of the present invention is to provide one group for treating the Chinese medicine of rheumatic arthritis
The arthritic problem of radical cure of rheumatic.
Technical scheme is as follows: one group for treating the Chinese medicine of rheumatic arthritis, by the original of following parts by weight
Material composition: excrementum pteropi 10-20g, fructus lycii 6-12g, Radix Salviae Miltiorrhizae 6-12g, radix paeoniae rubra 3-9g, rhizome of chuanxiong 5-15g, monkshood 5-15g, peach kernel 5-
15g, Radix Angelicae Sinensis 3-9g, Radix Glycyrrhizae 3-9g.
Preferably, the parts by weight group of each raw material becomes, excrementum pteropi 15g, fructus lycii 9g, Radix Salviae Miltiorrhizae 9g, radix paeoniae rubra 6g, rhizome of chuanxiong 10g, attached
Sub- 10g, peach kernel 10g, Radix Angelicae Sinensis 6g, Radix Glycyrrhizae 6g.
Said medicine preparation process is as follows: by material medicine excrementum pteropi, fructus lycii, Radix Salviae Miltiorrhizae, radix paeoniae rubra, rhizome of chuanxiong, monkshood, peach kernel,
Radix Angelicae Sinensis, Radix Glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry, and obtain aseptic raw material, then by nothing
Bacterium raw material are made Chinese materia medica preparation and can take.
Excrementum pteropi has promoting blood circulation to remove blood stasis in the present invention, and the function of fries charcoal hemostasis is monarch drug in a prescription.It is fructus lycii, Radix Salviae Miltiorrhizae, radix paeoniae rubra, rhizome of chuanxiong, attached
Sub nourishing liver and kidney, benefiting shrewd head, promoting blood circulation is inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle, heat-clearing, the scattered stasis of blood, promoting the circulation of qi, wind-dispelling,
Recuperating depleted yang, mends fire supporing yang, cold dispelling are ministerial drug.Peach kernel, Radix Angelicae Sinensis promoting blood circulation, relax bowel and defecation is relieving cough and asthma, enriches blood, and menstruation regulating stops
Pain is adjutant.Radix Glycyrrhizae is invigorated the spleen and benefited qi, moistening lung to arrest cough, clearing heat and detoxicating, alleviates analgesic, and coordinating the drug actions of a prescription is to make medicine.
The pharmacological property and its effect of each component of the present invention are as follows:
Excrementum pteropi, warm-natured, sweet in flavor, return liver warp.Major function: promoting blood circulation to remove blood stasis, fries charcoal hemostasis.The major functions: trusted subordinate's extravasated blood, pain
Through, blood stasis, postpartum congestion and abdominal pain, metrostaxis, traumatic injury.
Fructus lycii, it is mild-natured, it is sweet in flavor, return liver and kidney channel.Major function: nourishing liver and kidney, benefiting shrewd head.The major functions: vertigo,
Hypopsia, soreness and weakness of waist and knees, spermatorrhea, the deficiency of Yin are quenched one's thirst.
Radix Salviae Miltiorrhizae, meridian distribution of property and flavor: cold nature, bitter, converge to heart and liver channels.Major function: promoting blood circulation, inducing meastruation to relieve menalgia, clear away heart-fire and remove
It is tired, cool blood to disappear carbuncle.The major functions: chest impediment and cardialgia, stomach duct and abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea warp
It closes, sore swell and ache curative.
Radix paeoniae rubra, meridian distribution of property and flavor: cold nature, bitter, return liver warp.Major function: clearing heat and cooling blood, removing blood stasis and acesodyne.The major functions: hot
People's ying blood, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, amenorrhea and algomenorrhea, addiction lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore
Ulcer.
Rhizome of chuanxiong, meridian distribution of property and flavor: warm-natured, acrid flavour returns liver, gallbladder, pericardium channel.Major function: blood-activating and qi-promoting, wind-expelling pain-stopping.It is main
It controls: irregular menstruation, amenorrhea and algomenorrhea, abdominal pain, sternal rib shouting pain, tumbling and swelling, headache, rheumatic arthralgia.
Monkshood, property heat is acrid flavour, sweet, belongs to the heart, kidney, spleen channel.Major function: recuperating depleted yang, mends fire supporing yang, eliminating cold to stop pain.
The major functions: irregular menstruation, urine gonorrhoea, urine void are closed, ten refer to pain.
Peach kernel, mild-natured, bitter, sweet, return heart, liver, large intestine channel.Major function: promoting blood circulation, relax bowel and defecation, cough-relieving are flat
Asthma.The major functions: amenorrhea and algomenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Radix Angelicae Sinensis, meridian distribution of property and flavor: it is warm-natured, it is sweet in flavor, pungent, return liver, the heart, the spleen channel.Major function: replenishing and activating blood, menstruction regulating and pain relieving,
Relax bowel and defecation.The major functions: blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down,
Ulcer sores, dry constipation of intestines.
Radix Glycyrrhizae, mild-natured, sweet in flavor, return 12 warps.Major function: invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency is stopped
Bitterly, coordinating the drug actions of a prescription.The major functions: weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle swells sore
Poison alleviates drug toxicity, strong.
The Chinese medicine that the present invention treats rheumatic arthritis has promoting blood circulation to remove blood stasis, and fries charcoal hemostasis is nourishing liver and kidney, benefiting shrewd head,
Dissolving stasis, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle, the scattered stasis of blood, promoting the circulation of qi, wind-dispelling, recuperating depleted yang, mends fire supporing yang, cold dispelling, ease constipation are logical
Just, it relievings asthma, enriches blood, invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency, the effect of coordinating the drug actions of a prescription, and it is significant in efficacy, it takes effect
Fastly, securely and reliably, no obvious toxic-side effects can effectively treat rheumatic arthritis.
Specific embodiment
The following examples can further illustrate the present invention, but do not limit the invention in any way.
Embodiment 1, the drug for treating rheumatic arthritis form: excrementum pteropi 15g, fructus lycii 9g, Radix Salviae Miltiorrhizae 9g, radix paeoniae rubra
6g, rhizome of chuanxiong 10g, monkshood 10g, peach kernel 10g, Radix Angelicae Sinensis 6g, Radix Glycyrrhizae 6g.The present embodiment effect is best.
Embodiment 2, the drug for treating rheumatic arthritis form: excrementum pteropi 20g, fructus lycii 12g, Radix Salviae Miltiorrhizae 12g, radix paeoniae rubra
9g, rhizome of chuanxiong 15g, monkshood 15g, peach kernel 15g, Radix Angelicae Sinensis 9g, Radix Glycyrrhizae 9g.The present embodiment drug effect is stronger.
Embodiment 3, the drug for treating rheumatic arthritis form: excrementum pteropi 10g, fructus lycii 6g, Radix Salviae Miltiorrhizae 6g, radix paeoniae rubra
3g, rhizome of chuanxiong 5g, monkshood 5g, peach kernel 5g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 3g.Embodiment drug effect is slightly weak.
Above-described embodiment preparation process is as follows: by material medicine excrementum pteropi, fructus lycii, Radix Salviae Miltiorrhizae, radix paeoniae rubra, rhizome of chuanxiong, monkshood, peach
Benevolence, Radix Angelicae Sinensis, Radix Glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry, and obtain aseptic raw material, then
Chinese materia medica preparation, which is made, in aseptic raw material to take, and in each 1 time of daily evening in morning, 7 as a treatment course.
" clinical trial "
For the curative effect for showing drug of the present invention, take 300 patients for being diagnosed as rheumatic arthritis, cardinal symptom be joint and
Muscle it is migrans it is miserable, rewrite, the symptoms such as pain.
It is divided into two groups to be treated, wherein one group is control group, one group is observation group, and two groups of cases each 150, two groups sick
Example is in terms of age, gender, illness without comparativity.Control group presses by specification to leflunomide and methotrexate (MTX)
It uses, 7 as a treatment course, treats the 2-6 course for the treatment of；Drug made from observation group's one after each meal embodiment of the present invention 1, morning and evening each one
Secondary, 7 as a treatment course, treats the 2-6 course for the treatment of.Two groups with cardinal symptom: joint and muscle it is migrans it is miserable, rewrite, pain
Symptom mitigation be it is effective, with cardinal symptom: joint and muscle it is migrans it is miserable, rewrite, pain symptom disappear be fully recover.Vertical shelves
Stay to look into and be subject to Statistical Comparison, statistics shows to the results are shown in Table 1(control group curative effect situation) and table 2(experimental group curative effect situation), pass through
The effect of comparison to control group and experimental group, drug therapy rheumatic arthritis of the present invention is substantially better than leflunomide and first ammonia
The effect of pterin.Medication effect of the present invention: efficient: 88%, cure rate 83.3%.
Table 1.
Table 2.
" typical case ":
1, revive certain, female, 29 years old, occur joint and muscle it is migrans it is miserable, rewrite, pain symptom 1 month.Using of the present invention
Drug treated, once in the morning and once at night, 7 are as a treatment course, and after 2 courses for the treatment of are used in conjunction, joint and muscle are migrans miserable, again
Write, pain symptom mitigates, after 3 courses for the treatment of, joint and muscle it is migrans it is miserable, rewrite, pain symptom disappears.It is further continued for taking 1
A course for the treatment of day is to consolidate curative effect, and follow-up 2 years without recurrence.
2, Chen, male, 35 years old, occur joint and muscle it is migrans it is miserable, rewrite, pain symptom 2 months.Using the present invention
The drug is treated, and once in the morning and once at night, 7 are as a treatment course, after 3 courses for the treatment of are used in conjunction, joint and muscle it is migrans it is miserable,
Rewrite, pain symptom mitigates, after 4 courses for the treatment of, joint and muscle it is migrans it is miserable, rewrite, pain symptom disappears.It is further continued for taking
1 course for the treatment of day is to consolidate curative effect, and follow-up 2 years without recurrence.
Claims (2)
1. one group for treating the Chinese medicine of rheumatic arthritis, it is characterised in that it is made of the raw material of following parts by weight: five spirits
Rouge 10-20g, fructus lycii 6-12g, Radix Salviae Miltiorrhizae 6-12g, radix paeoniae rubra 3-9g, rhizome of chuanxiong 5-15g, monkshood 5-15g, peach kernel 5-15g, Radix Angelicae Sinensis 3-9g,
Radix Glycyrrhizae 3-9g.
2. the Chinese medicine for being used to treat rheumatic arthritis according to claim 1, it is characterised in that: the weight of each raw material
Part group becomes, excrementum pteropi 15g, fructus lycii 9g, Radix Salviae Miltiorrhizae 9g, radix paeoniae rubra 6g, rhizome of chuanxiong 10g, monkshood 10g, peach kernel 10g, Radix Angelicae Sinensis 6g, Radix Glycyrrhizae
6g。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710688812.3A CN109381559A (en) | 2017-08-13 | 2017-08-13 | One group for treating the Chinese medicine of rheumatic arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710688812.3A CN109381559A (en) | 2017-08-13 | 2017-08-13 | One group for treating the Chinese medicine of rheumatic arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109381559A true CN109381559A (en) | 2019-02-26 |
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ID=65415551
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710688812.3A Pending CN109381559A (en) | 2017-08-13 | 2017-08-13 | One group for treating the Chinese medicine of rheumatic arthritis |
Country Status (1)
| Country | Link |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101259201A (en) * | 2008-04-21 | 2008-09-10 | 全光彪 | Antirheumatic pain relieving medicaments |
| CN103007108A (en) * | 2011-09-20 | 2013-04-03 | 李秀芝 | Traditional Chinese medicine for treatments of rheumatic arthritis, rheumatoid arthritis and hyperosteogeny |
-
2017
- 2017-08-13 CN CN201710688812.3A patent/CN109381559A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101259201A (en) * | 2008-04-21 | 2008-09-10 | 全光彪 | Antirheumatic pain relieving medicaments |
| CN103007108A (en) * | 2011-09-20 | 2013-04-03 | 李秀芝 | Traditional Chinese medicine for treatments of rheumatic arthritis, rheumatoid arthritis and hyperosteogeny |
Non-Patent Citations (2)
| Title |
|---|
| 潘碧琦,等: "活血化淤通络法治疗类风湿性关节炎60例", 《实用中医药杂志》 * |
| 董庆平,等: "身痛逐瘀汤加味治疗风湿性关节炎38例疗效观察", 《四川中医》 * |
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Application publication date: 20190226 |