CN109381384A - A kind of oral cavity nursing agent containing friction factor - Google Patents
A kind of oral cavity nursing agent containing friction factor Download PDFInfo
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- CN109381384A CN109381384A CN201711434421.5A CN201711434421A CN109381384A CN 109381384 A CN109381384 A CN 109381384A CN 201711434421 A CN201711434421 A CN 201711434421A CN 109381384 A CN109381384 A CN 109381384A
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- oral cavity
- cavity nursing
- nursing agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
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- Mycology (AREA)
- Birds (AREA)
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- Cosmetics (AREA)
Abstract
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight: 0.5~2 part of Irish moss；1.5~4.5 parts of sodium lauroyl sarcosine；1.5~3.5 parts of Cocoamidopropyl betaine；28~40 parts of moisturizer；0.2~0.5 part of sweetener；0.3~0.7 part of thickener；30~50 parts of rubbing agent；10~25 parts of deionized water；0.3~0.8 part of glycyrrhiza glabra extract；The rubbing agent is the compounding of longan seed powder and Herba Euphorbiae Humifusae powder.By the present invention in that longan seed powder and the rubbing agent of the compounding of Herba Euphorbiae Humifusae powder as oral cavity nursing agent is used both effectively to drive away tooth stain, it is avoided that the phenomenon that therefore friction leads to bleeding gums again, and without adding new hemostatic compositions, to reduce the production cost of oral cavity nursing agent.
Description
Technical field
The present invention relates to a kind of technical field of daily necessities more particularly to a kind of oral cavity nursing agents containing friction factor.
Background technique
Periodontal disease is common mouth disease, and symptom mainly has bleeding gums, swelling, pain.There is statistics to show,
The main reason for periodontal disease is 35 years old or more crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But since patient is not easy
Discover, most people is not aware that oneself is suffered from this disease.Think to many human factor errors that people can just suffer from periodontal disease to old,
Actually 5 years old children can suffer from gingivitis.
Periodontosis is not only to influence the health of tooth, also will affect the health of whole body.Periodontosis is to whole body health in recent years
Influence caused the concern of people.Bacterial component and bacterial product be easy to be diffused by oral pocket ulcer surface nearby or
It is far apart organ, leads to or aggravate certain general diseases, such as coronary heart disease, low birth weight infant, diabetes, pulmonary infection disease
Occurrence and development, seriously endanger human health.It depends merely on stomatological hospital and drug therapy is to be unable to satisfy people's improvement oral cavity to be good for
The needs of Kang Shuiping, with the use of the oral cavity nursing health products with prevention and treatment periodontal disease, periodontal disease is gradually to obtain
To effectively prevention and control.
In order to preferably prevent and treat periodontal disease, many persons select and are added into rubbing agent in oral cavity nursing agent, but add
After entering rubbing agent, people's discovery gum when carrying out oral care using the oral cavity nursing agent with rubbing agent is easy bleeding, from
And it is be easy to cause infection, and in order to stop blooding, it also needs to be added into hemostatic compositions in also oral cavity nursing agent, must can increase in this way
Add the production cost of oral cavity nursing agent.
Summary of the invention
It is an object of the invention to overcome the shortcomings of that above and defect proposes a kind of oral care containing friction factor
Agent.
To achieve this purpose, the present invention adopts the following technical scheme:
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
0.5~2 part of Irish moss；
1.5~4.5 parts of sodium lauroyl sarcosine；
1.5~3.5 parts of Cocoamidopropyl betaine；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
15~30 parts of rubbing agent；
10~25 parts of deionized water；
0.3~0.8 part of glycyrrhiza glabra extract；
The rubbing agent is the compounding of longan seed powder and Herba Euphorbiae Humifusae powder.
It preferably, further include 0.02-0.06 portions of preservatives.
Preferably, the preservative be at least one of isothiazolinone, paraben esters, potassium sorbate or two kinds with
On mixture.
Preferably, the moisturizer is that the one or more of them of propylene glycol, butanediol or glycine betaine compounds.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener be sodium carboxymethylcellulose, hydroxyethyl cellulose, carbomer it is one or more
Compounding.
Preferably, longan seed powder, the size of Herba Euphorbiae Humifusae powder are 500-1000 mesh.If the powder used crosses conference
It is laborious when causing to brush teeth, cause the inconvenience brushed teeth；If too small, it is easy to remain in the gap of tooth in friction process, drops
Low friction, to reduce the ability of tooth stain expeling.And longan seed powder, Herba Euphorbiae Humifusae floury texture be not hard, not will cause
Injury of teeth.
The present invention has passed through the compounding that longan seed powder and Herba Euphorbiae Humifusae powder are added in oral cavity nursing agent as friction
Agent enables the oral cavity nursing agent obtained quickly to remove the dirt for being attached to dental surface, avoids tooth jaundice or long decayed tooth, together
When due to friction effect, gum is easy bleeding, and longan seed powder, humid euphorbia grass meal itself have effects that cooling blood and hemostasis, because
This uses longan seed powder and the compounding of Herba Euphorbiae Humifusae powder as the oral cavity nursing agent of rubbing agent and both effectively drives away tooth stain,
It can be avoided the phenomenon that therefore friction leads to bleeding gums again, and without adding new hemostatic compositions, to reduce oral cavity
The production cost of care agent.
Specific embodiment
The technical scheme of the invention is further explained by means of specific implementation.
Embodiment 1
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
0.5 part of Irish moss；
1.5 parts of sodium lauroyl sarcosine；
1.5 parts of Cocoamidopropyl betaine；
28 parts of glycine betaine；
0.2 part of saccharin sodium；
0.3 part of sodium carboxymethylcellulose；
Longan seed powder, Herba Euphorbiae Humifusae powder: additive amount is added by table 1；
0.02 part of paraben esters；
10 parts of deionized water；
0.3 part of glycyrrhiza glabra extract.
Table 1 is influence of the additive amount of rubbing agent to tooth stain ability is driven away
It can be obtained by table 1, after having used the rubbing agent of longan seed powder and Herba Euphorbiae Humifusae powder as compounding, it is dirty to drive away tooth
The ability of dirt enhances, and either can reach for the expeling dirt ability for the tooth stain for being aged 15 days or 30 days
To 91 or more, and it is optimal drive away soils be using longan seed powder and the compounding proportion of Herba Euphorbiae Humifusae powder be 2:1.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral cavity nursing agent, carry out small
The clinical hemostasis of the clinical hemostasis experiment mice of mouse is tested.
Clinical trial of stopping blooding supports gum using blank lotion, Yunnan Baiyao oral cavity nursing agent, Radix zanthoxyli and protects tooth oral care
The oral cavity nursing agent of agent, embodiment 1-1 into embodiment 1-3 is as examination object sample.
It is carried out using hemostasis observation method is damaged to mouse liver local woanded surface.Take kunming mice 108 of health, body
Weigh 18~22g, male and female dual-purpose.After anesthetized mice, liver is cut in left lobe of liver with operating scissors and is about 0.5cm, wide about 0.5cm, it is high
About 0.5cm after the blood for wiping ejection, immediately in situation portion spreading object sample 0.5g to be tried, oppresses 1min with 200g counterweight,
Counterweight is removed after 1min, haemostatic effect is observed, until not bleeding.Such as still bleeding, adds to apply and pressurize after trying object sample, every
30s observation is primary, records bleeding stopping period, is such as no more than 3min, being then denoted as can stop blooding；Such as fail to stop blooding more than 3min, is then denoted as
Fail to stop blooding, experimental result is shown in Table 2.
The clinical blood coagulation hemostasis experimental result of 2 mouse of table
| Try object sample | Experiment number | Bleeding stopping period |
| Blank lotion | 18 | > 3 |
| Colgate-Palmolive toothpaste | 18 | 2.65±0.22 |
| Crest toothpaste | 18 | 2.51±0.18 |
| The oral cavity nursing agent of embodiment 1-1 | 18 | 2.17±0.15 |
| The oral cavity nursing agent of embodiment 1-2 | 18 | 2.11±0.13 |
| The oral cavity nursing agent of embodiment 1-3 | 18 | 2.06±0.12 |
As shown in Table 3, the oral cavity nursing agent of embodiment 1-1 to embodiment 1-3 is to mouse liver local woanded surface bleeding due to trauma
There is apparent blood coagulation haemostatic effect.
Embodiment 2
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1.2 parts of Irish moss；
3.5 parts of sodium lauroyl sarcosine；
3.5 parts of Cocoamidopropyl betaine；
30 parts of butanediol；
0.3 part of saccharin sodium；
0.7 part of hydroxyethyl cellulose；
17 parts of longan seed powder, 8 parts of Herba Euphorbiae Humifusae powder；
0.06 part of potassium sorbate；
20 parts of deionized water；
0.8 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for 30 days tooth stains of ageing is 91/12 day.
Embodiment 3
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1 part of Irish moss；
4.5 parts of sodium lauroyl sarcosine；
2.5 parts of Cocoamidopropyl betaine；
32 parts of propylene glycol；
0.5 part of xylitol；
0.6 part of carbomer；
13.5 parts of longan seed powder, Herba Euphorbiae Humifusae powder 11.5；
0.04 part of isothiazolinone；
15 parts of deionized water；
0.5 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for 30 days tooth stains of ageing is 92/11 day.
Embodiment 4
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1.75 parts of Irish moss；
3 parts of sodium lauroyl sarcosine；
2.6 parts of Cocoamidopropyl betaine；
35 parts of glycine betaine；
0.3 part of saccharin sodium；
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer；
8 parts of longan seed powder 11, Herba Euphorbiae Humifusae powder；
Paraben esters 0.25,0.15 part of potassium sorbate；
22 parts of deionized water；
0.65 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 96/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for 30 days tooth stains of ageing is 92/19 day.
Embodiment 5
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1.6 parts of Irish moss；
2.5 parts of sodium lauroyl sarcosine；
3.2 parts of Cocoamidopropyl betaine；
30 parts of butanediol；
0.4 part of xylitol；
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 7 parts of Herba Euphorbiae Humifusae powder；
0.02 part of isothiazolinone, 0.03 part of paraben esters；
14 parts of deionized water；
0.7 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 96/9 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for 30 days tooth stains of ageing is 91/18 day.
Embodiment 6
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1.5 parts of Irish moss；
4 parts of sodium lauroyl sarcosine；
2.8 parts of Cocoamidopropyl betaine；
38 parts of propylene glycol；
0.3 part of xylitol, 0.2 part of saccharin sodium；
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer；
10 parts of longan seed powder, 11.5 parts of Herba Euphorbiae Humifusae powder；
0.05 part of isothiazolinone；
17.5 parts of deionized water；
0.4 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing 30 days tooth stains is 91/13 day.
Embodiment 7
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
2 parts of Irish moss；
4.5 parts of sodium lauroyl sarcosine；
3.2 parts of Cocoamidopropyl betaine；
10 parts of propylene glycol, 21 parts of glycine betaine；
0.3 part of saccharin sodium；
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer；
11 parts of longan seed powder, 11 parts of Herba Euphorbiae Humifusae powder；
0.01 part of isothiazolinone, 0.01 part of potassium sorbate；
14.5 parts of deionized water；
0.45 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/7 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for 30 days tooth stains of ageing is 92/12 day.
Embodiment 8
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
1.8 parts of Irish moss；
4.2 parts of sodium lauroyl sarcosine；
2.1 parts of Cocoamidopropyl betaine；
24 parts of butanediol, 10 parts of glycine betaine；
0.3 part of xylitol, 0.1 part of saccharin sodium；
0.55 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 15 parts of Herba Euphorbiae Humifusae powder；
0.01 part of isothiazolinone, 0.02 part of paraben esters；
20.5 parts of deionized water；
0.8 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing 30 days tooth stains is 91/17 day.
Embodiment 9
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
0.9 part of Irish moss；
1.8 parts of sodium lauroyl sarcosine；
2.7 parts of Cocoamidopropyl betaine；
Propylene glycol, butanediol or 28 parts of glycine betaine；
0.25 part of xylitol；
0.35 part of sodium carboxymethylcellulose；
8 parts of longan seed powder, 10 parts of Herba Euphorbiae Humifusae powder；
0.02 part of isothiazolinone, 0.01 part of paraben esters, 0.03 part of potassium sorbate；
15 parts of deionized water；
0.55 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing 30 days tooth stains is 91/15 day.
Embodiment 10
A kind of oral cavity nursing agent containing friction factor, includes following components in parts by weight:
0.8 part of Irish moss；
2.1 parts of sodium lauroyl sarcosine；
3.3 parts of Cocoamidopropyl betaine；
14 parts of propylene glycol, 23 parts of butanediol；
0.2 part of xylitol, 0.25 part of saccharin sodium；
0.5 part of carbomer；
12 parts of longan seed powder, 8 parts of Herba Euphorbiae Humifusae powder；
0.01 part of potassium sorbate, 0.02 part of isothiazolinone；
25 parts of deionized water；
0.35 part of glycyrrhiza glabra extract.
The oral cavity nursing agent of the present embodiment is 98/8 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing 30 days tooth stains is 92/12 day.
The technical principle of the invention is described above in combination with a specific embodiment.These descriptions are intended merely to explain the present invention
Principle, and shall not be construed in any way as a limitation of the scope of protection of the invention.Based on the explanation herein, this field
Technical staff can associate with other specific embodiments of the invention without creative labor, these modes are all
It will fall under the scope of the present invention.
Claims (7)
1. a kind of oral cavity nursing agent containing friction factor, which is characterized in that it includes following components in parts by weight:
0.5~2 part of Irish moss；
1.5~4.5 parts of sodium lauroyl sarcosine；
1.5~3.5 parts of Cocoamidopropyl betaine；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
30~50 parts of rubbing agent；
10~25 parts of deionized water；
0.3~0.8 part of glycyrrhiza glabra extract；
The rubbing agent is the compounding of longan seed powder and Herba Euphorbiae Humifusae powder.
2. a kind of oral cavity nursing agent containing friction factor according to claim 1, it is characterised in that: it further includes
0.02-0.06 portions of preservatives.
3. a kind of oral cavity nursing agent containing friction factor according to claim 2, it is characterised in that: the preservative is
The mixture of one or more of isothiazolinone, paraben esters, potassium sorbate.
4. a kind of oral cavity nursing agent containing friction factor according to claim 1, it is characterised in that: the moisturizer is
The one or more of them of propylene glycol, butanediol or glycine betaine compounds.
5. a kind of oral cavity nursing agent containing friction factor according to claim 1, it is characterised in that: the sweetener is
The one or two of saccharin sodium or xylitol.
6. a kind of oral cavity nursing agent containing friction factor according to claim 1, it is characterised in that: the thickener is
One or more compoundings of sodium carboxymethylcellulose, hydroxyethyl cellulose, carbomer.
7. a kind of oral cavity nursing agent containing friction factor according to claim 1, it is characterised in that: the longan seed powder
Last, Herba Euphorbiae Humifusae powder size is 500-1000 mesh.
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| CN201711434421.5A CN109381384A (en) | 2017-12-26 | 2017-12-26 | A kind of oral cavity nursing agent containing friction factor |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711434421.5A CN109381384A (en) | 2017-12-26 | 2017-12-26 | A kind of oral cavity nursing agent containing friction factor |
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| CN109381384A true CN109381384A (en) | 2019-02-26 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225576A (en) * | 1997-04-04 | 1999-08-11 | 奥普蒂瓦公司 | Antimicrobial agent for oral hygiene products |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104523562A (en) * | 2015-01-09 | 2015-04-22 | 俄热 | Tibetan worm grass, fritillaria and saffron crocus toothpaste |
| CN105342912A (en) * | 2015-11-12 | 2016-02-24 | 施庚伟 | Traditional Chinese medicine toothpaste adopting grape seed matrix abrasive and preparation method of traditional Chinese medicine toothpaste |
| CN105380855A (en) * | 2015-12-03 | 2016-03-09 | 赵凌霄 | Natural plant toothpaste and preparation method thereof |
-
2017
- 2017-12-26 CN CN201711434421.5A patent/CN109381384A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225576A (en) * | 1997-04-04 | 1999-08-11 | 奥普蒂瓦公司 | Antimicrobial agent for oral hygiene products |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104523562A (en) * | 2015-01-09 | 2015-04-22 | 俄热 | Tibetan worm grass, fritillaria and saffron crocus toothpaste |
| CN105342912A (en) * | 2015-11-12 | 2016-02-24 | 施庚伟 | Traditional Chinese medicine toothpaste adopting grape seed matrix abrasive and preparation method of traditional Chinese medicine toothpaste |
| CN105380855A (en) * | 2015-12-03 | 2016-03-09 | 赵凌霄 | Natural plant toothpaste and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 熊辅信等: "《中药现代研究荟萃》", 31 May 2002, 云南科技出版社 * |
| 老中医养生堂编著: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 * |
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