CN109364315A - A kind of band alternating temperature two-chamber membrane oxygenator - Google Patents
A kind of band alternating temperature two-chamber membrane oxygenator Download PDFInfo
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- CN109364315A CN109364315A CN201811493031.XA CN201811493031A CN109364315A CN 109364315 A CN109364315 A CN 109364315A CN 201811493031 A CN201811493031 A CN 201811493031A CN 109364315 A CN109364315 A CN 109364315A
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- 239000012528 membrane Substances 0.000 title claims abstract description 39
- 239000008280 blood Substances 0.000 claims abstract description 115
- 210000004369 blood Anatomy 0.000 claims abstract description 115
- 238000006213 oxygenation reaction Methods 0.000 claims abstract description 107
- 239000007789 gas Substances 0.000 claims abstract description 89
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 66
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 66
- 239000001301 oxygen Substances 0.000 claims abstract description 66
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 39
- 239000012510 hollow fiber Substances 0.000 claims description 49
- 230000004087 circulation Effects 0.000 claims description 8
- 239000000835 fiber Substances 0.000 claims description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract description 31
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract description 15
- 239000001569 carbon dioxide Substances 0.000 abstract description 15
- 235000012489 doughnuts Nutrition 0.000 description 16
- 229960004424 carbon dioxide Drugs 0.000 description 15
- 230000001413 cellular effect Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 238000005192 partition Methods 0.000 description 3
- 101100243025 Arabidopsis thaliana PCO2 gene Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 241000790917 Dioxys <bee> Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 229910002090 carbon oxide Inorganic materials 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention discloses a kind of band alternating temperature two-chamber membrane oxygenators, including upper cover, lower cover, intermediate connection cover, core shaft structure, oxygenation chamber, temperature-changing chamber；The oxygenation chamber includes the first oxygenation chamber and the second oxygenation chamber, is made of oxygen press mold, plugged zone；The core shaft structure includes upper mandrel, lower mandrel, and the upper mandrel is connected to lower mandrel sidewall spaces by connecting shaft, and is connected to oxygen press mold gap；The upper cover, intermediate connection cover, lower cover are connected to gas nozzle；The first oxygenation chamber top, bottom are separately connected the upper cover, intermediate connection cover；The second oxygenation chamber top, bottom are separately connected the intermediate connection cover, lower cover；The temperature-changing chamber is made of alternating temperature film, plugged zone, and connection water nozzle and blood inlet, the alternating temperature intermembrane space are connected to oxygen press mold gap；The oxygenation chamber is connected to blood outlet nozzle.The present invention is adjusted blood temperature, can also effectively adjust carbon dioxide and oxygen content in blood according to demand before blood carries out gas exchanges.
Description
Technical field
The present invention relates to medical instruments fields, and in particular to a kind of band alternating temperature two-chamber membrane oxygenator.
Background technique
Hollow fiber membrane oxygenator (hereinafter referred to as oxygenator) is the goldstandard of current blood oxygenation, in long-term use
In the process, a kind of instrument of the support openheart surgery of oxygenator from the beginning is gradually applied to more medical fields, such as breathes
Support, first aid etc..
The binding ability of hemoglobin and oxygen in blood is influenced by carbon dioxide partial pressure (PCO2), when PCO2 liter
The binding ability of Gao Shi, hemoglobin and oxygen reduces.And oxygenator completes blood and when gas exchanges, blood side and gas
The oxygen that the difference in oxygen concentration of side directly affects blood closes effect, and carbon dioxide partial pressure is then mainly related with the flowing velocity of gas.
Membrane oxygenator currently on the market is the design of pure gas inverting chamber, and this design can only be passed through when in use
A kind of gas or the identical mixed gas of concentration, therefore the gas both needs to keep certain oxygen concentration when flowing through oxygenator
Guarantee that certain air velocity guarantees the quick removing of carbon dioxide again for the oxygen content adjustment in blood, so as to cause
The oxygen content of blood and carbon dioxide content effectively and rapidly adjusted in blood can not be reached when use, and cause a large amount of of gas
Waste, especially when division of respiratory disease or applicable object are the elderly, when use, needs better carbon dioxide elimination ability.
Summary of the invention
In view of this, being used in blood oxygenation an embodiment of the present invention is intended to provide a kind of band alternating temperature two-chamber membrane oxygenator
In not only adjustable blood temperature, can also effectively adjust the carbon dioxide content in blood, while again can be effectively
The oxygen content of blood in blood is adjusted, furthermore it is also possible to carry out as individual band alternating temperature oxygenator using or as individual
Band alternating temperature carbon dioxide ejector uses.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows:
The embodiment of the invention provides a kind of band alternating temperature two-chamber membrane oxygenators, including upper cover, lower cover, further include intermediate connection
Lid, core shaft structure, oxygenation chamber, temperature-changing chamber；The oxygenation chamber includes the first oxygenation chamber and the second oxygenation chamber, by oxygen press mold, is set
The plugged zone at the top and bottom of the oxygen press mold is set to constitute；The core shaft structure includes upper mandrel, lower mandrel, the upper mandrel
Be connected to lower mandrel sidewall spaces by connecting shaft, and the upper mandrel and lower mandrel sidewall spaces with oxygen press mold gap
Connection；The upper cover, intermediate connection cover, lower cover are communicated with gas nozzle；The first oxygenation chamber top, bottom are separately connected described
Upper cover, intermediate connection cover；The second oxygenation chamber top, bottom are separately connected the intermediate connection cover, lower cover；The temperature-changing chamber
It is constituted by alternating temperature film, the plugged zone being arranged at the top and bottom of the alternating temperature film, and is communicated with water nozzle and blood inlet, the alternating temperature
Intermembrane space is connected to oxygen press mold gap；The oxygenation chamber is communicated with blood outlet nozzle.
Further, the temperature-changing chamber is communicated with water nozzle and blood inlet includes: that the temperature-changing chamber is communicated with water inlet tap, water outlet
Mouth, blood inlet.
Further, the oxygenation chamber is communicated with blood outlet nozzle and includes:
The temperature-changing chamber is connected with second oxygenation chamber, and first oxygenation chamber is communicated with blood outlet nozzle；
Or the temperature-changing chamber is connected with first oxygenation chamber, second oxygenation chamber is communicated with blood outlet nozzle.
Further, the oxygen press mold is made of hollow fiber conduit, and the alternating temperature film is made of hollow fiber conduit, the envelope
Blocking layer is in honeycomb structure.
Further, the plugged zone of the honeycomb structure is directed at connection with the hollow fiber conduit nozzle.
Further, the upper cover is communicated with the first suction nozzle, and the intermediate connection cover is communicated with first row gas nozzle, described
Lower cover is communicated with second row gas nozzle.
Further, it is equipped with partition in the intermediate connection cover or is connected to first oxygenation chamber and second oxygenation chamber
The plug-in switch of middle gas circulation.
Further, the core shaft structure further include: the mandrel link block of the connection upper mandrel and lower mandrel.
The present invention has the beneficial effect that: 1) present invention, which is used in blood oxygenation, can efficiently solve oxygen exchange and two
The problem of carbonoxide excludes improves oxygenation efficiency；2) present invention be also used as individually band alternating temperature oxygenator carry out using；3)
The present invention is also used as individually band alternating temperature carbon dioxide ejector and uses；It is 4) of the invention before blood carries out gas exchanges,
Adjustable blood temperature.
Detailed description of the invention
Fig. 1 is perspective view of the first embodiment with alternating temperature two-chamber membrane oxygenator of the invention；
Fig. 2 is the first embodiment band alternating temperature two-chamber membrane oxygenator sectional structure chart of the invention；
Fig. 3 (a) is the first embodiment of the invention with the core shaft structure floor map in alternating temperature two-chamber membrane oxygenator；
Fig. 3 (b) is the first embodiment of the invention with the upper mandrel inside structure figure in alternating temperature two-chamber membrane oxygenator；
Fig. 4 flows from above to below for the first embodiment of the invention with the blood in alternating temperature two-chamber membrane oxygenator and water flowing
Schematic diagram；
Fig. 5 is one of the first embodiment band alternating temperature two-chamber membrane oxygenator of the invention gas flow pattern schematic diagram；
Fig. 6 is that second of embodiment of the invention flows from bottom to top with the blood in alternating temperature two-chamber membrane oxygenator and water flowing is shown
It is intended to；
Fig. 7 is one of second of embodiment band alternating temperature two-chamber membrane oxygenator of present invention gas flow pattern schematic diagram；
Wherein: 1 being upper cover, 2 be lower cover, 3 be intermediate connection cover, 4 be oxygen press mold, 5 be plugged zone in oxygenation chamber, 6 be upper core
Axis, 7 be lower mandrel, 8 be mandrel link block, 9 be connecting shaft, 10 be upper mandrel sidewall spaces, 11 be lower mandrel sidewall spaces, 12
It is the first suction nozzle, 13 be first row gas nozzle, 14 be the second suction nozzle, 15 be second row gas nozzle, 16 be alternating temperature film, 17 is alternating temperature
Plugged zone in room, 18 be water inlet tap, 19 be faucet, 20 be blood inlet, 21 be temperature-changing chamber shell, 22 be blood outlet nozzle.
Specific embodiment
In order to more fully hereinafter understand the features of the present invention and technology contents, with reference to the accompanying drawing to reality of the invention
It is now described in detail, appended attached drawing purposes of discussion only for reference, is not used to limit the present invention.
Fig. 1 is perspective view of the first embodiment with alternating temperature two-chamber membrane oxygenator of the invention, as shown in Figure 1, the band
Alternating temperature two-chamber membrane oxygenator includes upper cover 1, lower cover 2, intermediate connection cover 3, the between upper cover 1 and intermediate connection cover 3
One oxygenation chamber and temperature-changing chamber, the second oxygenation chamber between intermediate connection cover 3 and lower cover 2, the upper cover be communicated with first into
Gas nozzle 12, water inlet tap 18, the intermediate connection cover is communicated with the first outlet nozzle 13, faucet 19, the second suction nozzle 14, under described
Lid is communicated with the second outlet nozzle 15, and the oxygenator is also communicated with blood inlet 20, blood outlet nozzle 22.
Here, the water inlet tap of the upper cover connection is connected to temperature-changing chamber, the faucet of intermediate connection cover connection namely connection
Temperature-changing chamber.
As shown in Figure 2, Fig. 2 is the first embodiment band alternating temperature two-chamber membrane oxygenator section of the invention to specific internal structure
Structure chart, including upper cover 1, lower cover 2 further include intermediate connection cover 3, core shaft structure, oxygenation chamber, temperature-changing chamber；The oxygenation chamber packet
The first oxygenation chamber and the second oxygenation chamber are included, is made of oxygen press mold 4, the plugged zone 5 being arranged at the top and bottom of the oxygen press mold；
The core shaft structure includes upper mandrel 6, lower mandrel 7, and the upper mandrel is connected to lower mandrel sidewall spaces by connecting shaft 9, and
The upper mandrel sidewall spaces 10 and lower mandrel sidewall spaces 11 are connected to 4 gap of oxygen press mold；The upper cover 1, centre
Connection cover 3, lower cover 2 are communicated with gas nozzle；The first oxygenation chamber top, bottom are separately connected the upper cover 1, intermediate connection cover
3；The second oxygenation chamber top, bottom are separately connected the intermediate connection cover 3, lower cover 2；The temperature-changing chamber by alternating temperature film 16,
The plugged zone 17 at the top and bottom of the alternating temperature film is arranged in constitute, and is communicated with water nozzle and blood inlet 20, the alternating temperature film 16
Gap is connected to 4 gap of oxygen press mold；The oxygenation chamber is communicated with blood outlet nozzle 22.
Further, the temperature-changing chamber is communicated with water nozzle and blood inlet includes: that the temperature-changing chamber is communicated with water inlet tap 18, goes out
Water nozzle 19, blood inlet 20.
Here, the water inlet tap of the temperature-changing chamber connection is connected on the cover, the faucet of the temperature-changing chamber connection
I.e. connection is in the intermediate connection cover.
Further, the oxygenation chamber is communicated with blood outlet nozzle and includes:
The temperature-changing chamber is connected with second oxygenation chamber, and first oxygenation chamber is communicated with blood outlet nozzle；
Or the temperature-changing chamber is connected with first oxygenation chamber, second oxygenation chamber is communicated with blood outlet nozzle.
Here, temperature-changing chamber described in Fig. 2 is connected with first oxygenation chamber, so being connected to bleeding in the second oxygenation chamber
Mouth 22.
Further, the oxygen press mold 4 is made of hollow fiber conduit, and the alternating temperature film 16 is made of hollow fiber conduit, institute
Plugged zone is stated in honeycomb structure.
Further, the plugged zone of the honeycomb structure is directed at connection with the hollow fiber conduit nozzle.
Further, the upper cover 1 is communicated with the first suction nozzle 12, and the intermediate connection cover 3 is communicated with first row gas nozzle
13, the second suction nozzle 14, the lower cover 2 are communicated with second row gas nozzle 15.
Here, when blood is entered in temperature-changing chamber by blood inlet 20, blood engorgement is made of many hollow fiber conduits
In alternating temperature film 16, i.e., blood is covered in the doughnut pipe outer wall, separates with the water flow to circulate in the hollow fiber conduit.
Correspondingly, when blood enters in the first oxygenation chamber from the temperature-changing chamber, blood engorgement is by many hollow fibres
It ties up in the oxygen press mold 4 that pipe is constituted, i.e., blood is covered in the doughnut pipe outer wall, with the gas to circulate in the hollow fiber conduit
Body separates.
Here, blood enters the first oxygenation chamber from the temperature-changing chamber and enters particular by the hole on temperature-changing chamber shell 21
In first oxygenation chamber.
Here, the water flow come in from the water inlet tap 18 enters the hollow fiber conduit by the plugged zone of honeycomb structure
It is interior, and go out from the honeycomb structure plugged zone 17 of 16 bottom of alternating temperature film.
Here, pass through the closure of honeycomb structure in first oxygenation chamber from the gas that first suction nozzle 12 is come in
Layer 5 enters in the hollow fiber conduit, and goes out from the honeycomb structure plugged zone of oxygen press mold bottom.
Further, partition is equipped in the intermediate connection cover 3 or be connected to first oxygenation chamber and second oxygen conjunction
The plug-in switch that gas circulates in room.
Here, independent double-layer structure is equipped in the intermediate connection cover 3, it is slotting in the intermediate connection cover when being arranged in
When pin switch is closed, the first outlet nozzle 13 being connected in the intermediate connection cover is not communicated with the second suction nozzle 14, i.e., only
It works in vertical double-layer structure, correspondingly, first oxygenation chamber is separated with the gas circulation in the second oxygenation chamber；Work as setting
When plug-in switch in the intermediate connection cover is opened, the first outlet nozzle 13 for being connected in the intermediate connection cover 3 and the
Two suction nozzles 14 communicate, and correspondingly, first oxygenation chamber is connected to the gas circulation in the second oxygenation chamber, therefore, it is desirable to
Second suction nozzle 14 is blocked, i.e., described second suction nozzle 14 is not passed through gas, is not so passed through from the second suction nozzle 14
Gas can be expelled directly out from first outlet nozzle 13.
Further, the core shaft structure further include: the mandrel link block 8 of the connection upper mandrel 6 and lower mandrel 7.
Fig. 3 (a) is the first of the invention embodiment with the core shaft structure floor map in alternating temperature two-chamber membrane oxygenator,
As shown, including the mandrel link block 8 of upper mandrel 6, lower mandrel 7, the connection upper mandrel and lower mandrel.
Here, the core shaft structure is that position, the mandrel knot is arranged among the band alternating temperature two-chamber membrane oxygenator
Structure center is solid construction, and the upper mandrel sidewall spaces 10 and lower mandrel sidewall spaces 11 are connected to oxygen press mold gap,
The upper mandrel sidewall spaces 10 are connected to lower mandrel sidewall spaces 11 by connecting shaft.
Here, the side of the upper mandrel sidewall spaces 10 and lower mandrel sidewall spaces 11 and the oxygen press mold gap-contact
There is the gap 101 passed through for blood, therefore the upper mandrel sidewall spaces and lower mandrel sidewall spaces are between the oxygen press mold
Gap connection.
Fig. 3 (b) is the first embodiment of the invention with the upper mandrel inside structure figure in alternating temperature two-chamber membrane oxygenator, such as
It is solid construction among upper mandrel 6 shown in figure, side wall forms space 10, has blood supply with the side of the oxygen press mold gap-contact
The gap 101 that liquid passes through.
Here, lower mandrel inside structure repeats no more as above-mentioned upper mandrel inside structure.
Fig. 4 flows from above to below for the first embodiment of the invention with the blood in alternating temperature two-chamber membrane oxygenator and water
Flow schematic diagram, as shown in figure 4, the temperature-changing chamber bottom is equipped with blood inlet, second oxygenation chamber bottom is equipped with blood outlet nozzle.
Here, when blood enters the temperature-changing chamber from the blood inlet, blood can be filled by many hollow fiber conduits
In the alternating temperature film of composition, i.e. blood is covered in the doughnut pipe outer wall, by with flowing water in the hollow fiber conduit
After stream carries out cold and hot exchange, entered in first oxygenation chamber by the hole on the temperature-changing chamber shell, blood can also fill at this time
Be full of in the oxygen press mold being made of many hollow fiber conduits, i.e. blood is covered in the doughnut pipe outer wall, by with it is described
After the gas molecule exchange flowed in hollow fiber conduit, by upper mandrel sidewall spaces be connected to the oxygen press mold, to dirty
It is logical, successively by connecting connecting shaft, the lower mandrel sidewall spaces of the lower mandrel and upper mandrel sidewall spaces, enter later described
In second oxygenation chamber, blood is equally covered in the doughnut pipe outer wall, and by with flowed in the hollow fiber conduit
After gas molecule exchange, the blood outlet nozzle being arranged from second oxygenation chamber bottom is gone out.
Here, blood carries out cold and hot exchange in the temperature-changing chamber can be the temperature by adjusting water flow specifically to control
Blood temperature.
Here, blood carries out gas molecule exchange in first oxygenation chamber specifically can be by adjusting gas in institute
The speed flowed in hollow fiber conduit is stated to divide to control the carbon dioxide in blood.
Here, blood carries out gas molecule exchange in second oxygenation chamber specifically can be by adjusting oxygen in gas
Concentration controls the partial pressure of oxygen and blood oxygen saturation in blood, and such as the second oxygenation chamber is passed through the empty oxygen that oxygen concentration is 66% and mixes
Gas, by blood partial pressure of oxygen and blood oxygen saturation be promoted to operation it is clinical needed for.
The above realizes temperature of the blood in this example belt alternating temperature two-chamber membrane oxygenator and adjusts, is complete twice
Gas exchange process, specific gas flow pattern are shown in Fig. 5.
Fig. 5 is the gas flow pattern signal of one of the first embodiment band alternating temperature two-chamber membrane oxygenator of the invention
Figure, as shown, the first suction nozzle and the second suction nozzle for being connected to of centre connection cover that the gas is connected to from upper cover respectively into
Enter, and goes out respectively from the second outlet nozzle that the first outlet nozzle that intermediate connection cover is connected to is connected to lower cover.
Here, independent double-layer structure is equipped in the intermediate connection cover.
Here, the plug-in switch of the intermediate connection cover setting is to close, that is, has separated first oxygenation chamber and institute
The gas circulation in the second oxygenation chamber is stated, but also the independent double-layer structure operating alone being equipped in the intermediate connection cover, i.e.,
The second suction nozzle that gas will not be made to be connected to from the intermediate connection cover is passed to the first outlet that the intermediate connection cover is connected to
At mouth.
Here, the second suction nozzle that the gas is connected to from intermediate connection cover enters, and is entered by cellular plugged zone
In many a hollow fiber conduits in communication, and go out from the honeycomb plugged zone that the hollow fiber conduit bottom end is attached thereto
It goes, goes out finally by the second outlet nozzle that the lower cover is connected to.
Here, the second suction nozzle that the gas is connected to from intermediate connection cover enters, and can be covered with the intermediate connection cover tool
There is autonomous working structure sheaf one week, and is circulated down by the cellular plugged zone.
Likewise, the first suction nozzle that the gas is connected to from upper cover enters, entered therewith by cellular plugged zone
It in many a hollow fiber conduits of connection, and goes out from the honeycomb plugged zone that the hollow fiber conduit bottom end is attached thereto, most
It is gone out afterwards by the first outlet nozzle of the intermediate connection cover connection.
Here, gas can be carried out by additional components from the gas that the first suction nozzle that the intermediate connection cover is connected to enters
Flow velocity adjustment divides by adjusting the speed that gas flows in the hollow fiber conduit to control the carbon dioxide in blood.
Here, from the upper cover be connected to the second suction nozzle enter gas contain suitable oxygen concentration, by adjusting
The gas oxygen concentration to circulate in the hollow fiber conduit controls the partial pressure of oxygen and blood oxygen saturation in blood.
Here, when the band alternating temperature two-chamber membrane oxygenator works, water flowing, blood flow, gas are flowed while being carried out.
Fig. 6 is that the blood in second of embodiment two-chamber membrane oxygenator of the invention flows from bottom to top and water flowing is illustrated
The setting of figure, i.e. temperature-changing chamber is connected with the second oxygenation chamber, as shown in fig. 6, the temperature-changing chamber bottom is equipped with blood inlet, described first
Oxygenation chamber bottom is equipped with blood outlet nozzle, and kinetic pump is equipped on the blood inlet interface of temperature-changing chamber bottom end connection.Blood is from alternating temperature
The blood inlet of room bottom connection enters, and in the full alternating temperature film being made of many hollow fiber conduits, i.e., blood is covered in institute
Doughnut pipe outer wall is stated, after carrying out cold and hot exchange with flowing water stream in the hollow fiber conduit, passes through the alternating temperature
Hole on the shell of room enters in second oxygenation chamber, and blood can also fill the oxygen pressure being made of many hollow fiber conduits at this time
In film, i.e., blood is covered in the doughnut pipe outer wall, by exchanging with the gas molecule flowed in the hollow fiber conduit
Afterwards, it by the lower mandrel sidewall spaces being connected to the oxygen press mold, circulates upwards, successively by connecting the lower mandrel and upper core
The connecting shaft of axis sidewall spaces, upper mandrel sidewall spaces enter in first oxygenation chamber later, and blood is equally covered with described
Doughnut pipe outer wall, and after being exchanged with the gas molecule flowed in the hollow fiber conduit, from first oxygenation chamber
The blood outlet nozzle of bottom setting is gone out.
It should be noted that the first suction nozzle that the preferred gas of embodiment is connected to from upper cover here is closed into first oxygen
Room, and the second row gas nozzle discharge that the first row gas nozzle being connected to from intermediate connection cover and the second oxygenation chamber bottom are connected to, i.e., it is described
The plug-in switch of intermediate connection cover setting is open, the gas being connected in first oxygenation chamber and second oxygenation chamber
Circulation, specific gas flow pattern are shown in Fig. 7.
Here, the gas being connected in first oxygenation chamber and second oxygenation chamber circulates, and also can just make the hair
It is bright use using or separately as carbon dioxide ejector separately as oxygenator.
Blood carries out cold and hot exchange in the temperature-changing chamber can be the temperature by adjusting water flow specifically to control blood
Temperature.
Blood carried out in second oxygenation chamber and the first oxygenation chamber gas molecule exchange specifically can be by adjusting
Oxygen concentration controls the partial pressure of oxygen and blood oxygen saturation in blood in gas, and such as the first oxygenation chamber and the second oxygenation chamber flow through oxygen
The empty oxygen gas mixture that concentration is 66%, by blood partial pressure of oxygen and blood oxygen saturation be promoted to operation it is clinical needed for, i.e. the hair
It is bright separately as oxygenator carry out using.
Or blood carries out specific can be of gas molecule exchange in second oxygenation chamber and the first oxygenation chamber and passes through
The speed that gas flows in the hollow fiber conduit in first oxygenation chamber and the second oxygenation chamber is adjusted to control in blood
Carbon dioxide partial pressure, i.e., the invention separately as carbon dioxide ejector carry out using.
Here, when the band alternating temperature two-chamber membrane oxygenator works, water flowing, blood flow, gas are flowed while being carried out.
Fig. 7 is the gas flow pattern signal of one of second of embodiment band alternating temperature two-chamber membrane oxygenator of the present invention
Figure, as shown in fig. 7, the type of flow of gas can be such that the embodiment of the present invention carries out separately as the oxygenator with alternating temperature in Fig. 7
It is used using or separately as the carbon dioxide ejector with alternating temperature.
Here, having partition or being connected to first oxygenation chamber for being arranged in the intermediate connection cover is closed with second oxygen
The plug-in switch that gas circulates in room is open, that is, the gas being connected in first oxygenation chamber and second oxygenation chamber
Circulation, i.e. gas enter from the first suction nozzle of the upper cover, the first outlet nozzle for being connected to respectively from the intermediate connection cover and
Second outlet nozzle of lower cover connection is gone out.
Specifically, the gas is connected to from upper cover the first suction nozzle enters, and is covered with entire upper cover one week, and from described the
Cellular plugged zone enters in the hollow fiber conduit in one oxygenation chamber, and the plugged zone from the hollow fiber conduit bottom end
It is passed in the intermediate connection cover, and is covered with the intermediate connection cover one week, a part of gas connects from the intermediate connection cover
The first logical outlet nozzle is gone out, and another part gas continues to be passed in second oxygenation chamber, i.e., is closed by second oxygen
The honeycomb plugged zone on interior hollow fibre pipe top enters, and comes out from the honeycomb plugged zone of the doughnut bottom of the tube,
It is covered with the lower cover one week, and goes out from the second outlet nozzle that the lower cover is connected to.
Here, when the gas that the first suction nozzle being connected to from the upper cover enters contains suitable oxygen concentration, the present invention
Embodiment can be carried out separately as the oxygenator with alternating temperature using；When the gas that the first suction nozzle being connected to from the upper cover enters
Body, by adjusting gas in the hollow fiber conduit when flow velocity, the embodiment of the present invention can be separately as the dioxy with alternating temperature
Change carbon ejector carry out using.
For Fig. 4 and Fig. 5 embodiment, using the band alternating temperature two-chamber membrane oxygenator, the water inlet tap of upper cover connection into
Enter the water flow of certain temperature, and is entered in hollow fiber conduit by the plugged zone of temperature-changing chamber；First air inlet of the upper cover connection
Mouth enters the gas of certain flow rate and coconnected second suction nozzle of the intermediate connection cover enters containing appropriate oxygen concentration
Gas, and entered in hollow fiber conduit by the plugged zone of the first oxygenation chamber and the second oxygenation chamber；Blood is from the temperature-changing chamber bottom
The blood inlet of end connection enters in the alternating temperature film being made of multiple hollow fiber conduits, i.e., blood is covered with outside the hollow fiber conduit
Wall, by after carrying out cold and hot exchange into flowing water stream in the temperature-changing chamber hollow fiber conduit, blood passes through the alternating temperature
Hole on the shell of room enters in first oxygenation chamber, that is, enters in the oxygen press mold being made of multiple hollow fiber conduits, blood cloth
It is full in the doughnut pipe outer wall, by with enter after the gas molecule flowed in the hollow fiber conduit exchanges, by with
The upper mandrel sidewall spaces of the oxygen press mold connection, circulate downwards, successively empty by connecting the upper mandrel and lower mandrel side wall
Between connecting shaft, lower mandrel sidewall spaces, later enter second oxygenation chamber in, blood is equally covered in the doughnut
Pipe outer wall, and after being exchanged with the gas molecule flowed in the hollow fiber conduit, it is arranged from second oxygenation chamber bottom end
Blood outlet nozzle go out；The faucet outlet being connected to simultaneously from the water flow that water inlet tap enters from intermediate connection cover；In addition from described
The gas that the second suction nozzle that first suction nozzle of lid connection is connected to the intermediate connection cover enters connects from the centre respectively
The second outlet nozzle that the first outlet nozzle that lid is connected to is connected to the lower cover is connect to go out.
For Fig. 6 and Fig. 7 embodiment, using the band alternating temperature two-chamber membrane oxygenator, the intermediate connection cover connection into
Water nozzle enters the water flow of certain temperature, and is entered in hollow fiber conduit by the plugged zone of temperature-changing chamber；The of upper cover connection
One suction nozzle enters the gas of certain flow rate, and enters in hollow fiber conduit and enter by the plugged zone of the first oxygenation chamber
In hollow fiber conduit in second oxygenation chamber；The blood inlet that blood is connected to from the temperature-changing chamber bottom end enters by multiple doughnuts
In the alternating temperature film that pipe is constituted, i.e. blood is covered in the doughnut pipe outer wall, by with enter the temperature-changing chamber doughnut
After flowing water stream carries out cold and hot exchange in pipe, blood enters second oxygenation chamber by the hole on the temperature-changing chamber shell
In, that is, enter in the oxygen press mold that is made of multiple hollow fiber conduits, blood is covered in the doughnut pipe outer wall, by with into
After entering the gas molecule exchange flowed in the hollow fiber conduit, by the lower mandrel sidewall spaces being connected to the oxygen press mold,
Circulation upwards, successively by connecting connecting shaft, the upper mandrel sidewall spaces of the lower mandrel and upper mandrel sidewall spaces, it is laggard
Enter in first oxygenation chamber, blood is equally covered in the doughnut pipe outer wall, and by in the hollow fiber conduit
After the gas molecule exchange of flowing, the blood outlet nozzle being arranged from first oxygenation chamber bottom is gone out；Enter simultaneously from water inlet tap
The faucet outlet that water flow is connected to from lower cover；In addition the gas that the first suction nozzle being connected to from the upper cover enters is respectively from described
The second outlet nozzle that first outlet nozzle of intermediate connection cover connection is connected to the lower cover is gone out.
The concrete model of device referred to above is with no restriction and detailed description, device referred to above go deep into connection side
Formula is not described in detail, as common knowledge, those skilled in the art can understand that.
The embodiment of the present invention only introduces its specific embodiment, does not limit the protection scope thereof.The technology of the industry
Personnel can make certain modifications under the inspiration of the present embodiment, thus all equivalence changes done according to the invention patent range or
Modification, belongs in the invention patent scope of the claims.
Claims (8)
1. a kind of band alternating temperature two-chamber membrane oxygenator, including upper cover, lower cover, which is characterized in that further include intermediate connection cover, mandrel
Structure, oxygenation chamber, temperature-changing chamber；The oxygenation chamber includes the first oxygenation chamber and the second oxygenation chamber, by oxygen press mold, is arranged described
Plugged zone at the top and bottom of oxygen press mold is constituted；The core shaft structure includes upper mandrel, lower mandrel, the upper mandrel and lower mandrel
Sidewall spaces are connected to by connecting shaft, and the upper mandrel and lower mandrel sidewall spaces are connected to oxygen press mold gap；Institute
It states upper cover, intermediate connection cover, lower cover and is communicated with gas nozzle；At the top of first oxygenation chamber, bottom be separately connected the upper cover, in
Between connection cover；The second oxygenation chamber top, bottom are separately connected the intermediate connection cover, lower cover；The temperature-changing chamber is by alternating temperature
Film, the plugged zone being arranged at the top and bottom of the alternating temperature film constitute, and are communicated with water nozzle and blood inlet, the alternating temperature intermembrane space
It is connected to oxygen press mold gap；The oxygenation chamber is communicated with blood outlet nozzle.
2. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that the temperature-changing chamber is communicated with
Water nozzle and blood inlet include: that the temperature-changing chamber is communicated with water inlet tap, faucet, blood inlet.
3. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that the oxygenation chamber is communicated with
Blood outlet nozzle includes:
The temperature-changing chamber is connected with second oxygenation chamber, and first oxygenation chamber is communicated with blood outlet nozzle；
Or the temperature-changing chamber is connected with first oxygenation chamber, second oxygenation chamber is communicated with blood outlet nozzle.
4. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that the oxygen press mold is by hollow
Fibre pipe is constituted, and the alternating temperature film is made of hollow fiber conduit, and the plugged zone is in honeycomb structure.
5. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 4, which is characterized in that the honeycomb structure
Plugged zone is directed at connection with the hollow fiber conduit nozzle.
6. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that the upper cover is communicated with
One suction nozzle, the intermediate connection cover are communicated with first row gas nozzle, and the lower cover is communicated with second row gas nozzle.
7. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that in the intermediate connection cover
Equipped with the plug-in switch for separating or being connected to gas circulation in first oxygenation chamber and second oxygenation chamber.
8. a kind of band alternating temperature two-chamber membrane oxygenator according to claim 1, which is characterized in that the core shaft structure is also
It include: the mandrel link block for connecting the upper mandrel and lower mandrel.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811493031.XA CN109364315A (en) | 2018-12-07 | 2018-12-07 | A kind of band alternating temperature two-chamber membrane oxygenator |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811493031.XA CN109364315A (en) | 2018-12-07 | 2018-12-07 | A kind of band alternating temperature two-chamber membrane oxygenator |
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| CN109364315A true CN109364315A (en) | 2019-02-22 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023284152A1 (en) * | 2021-07-14 | 2023-01-19 | 江苏赛腾医疗科技有限公司 | Membrane oxygenator having built-in filter |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201510571U (en) * | 2009-09-29 | 2010-06-23 | 山东威高新生医疗器械有限公司 | Membrane type oxygenator |
| US20100272605A1 (en) * | 2009-04-23 | 2010-10-28 | Kevin Mclntosh | Radial design oxygenator with heat exchanger and pump |
| CN201978219U (en) * | 2011-02-09 | 2011-09-21 | 朱宗涛 | Flow-controllable blood extracorporeal circulation oxygenator |
| CN203663149U (en) * | 2014-01-08 | 2014-06-25 | 陈樱 | Membrane oxygenator |
| CN105828848A (en) * | 2013-12-23 | 2016-08-03 | 马里兰大学，巴尔的摩 | Blood oxygenator |
| CN105833373A (en) * | 2016-06-13 | 2016-08-10 | 北京米道斯医疗器械有限公司 | Hollow fiber membrane oxygenator and method |
| CN109364314A (en) * | 2018-12-07 | 2019-02-22 | 江苏美思康医疗科技有限公司 | A kind of two-chamber membrane oxygenator and oxygen close method |
| CN209286304U (en) * | 2018-12-07 | 2019-08-23 | 江苏美思康医疗科技有限公司 | A kind of two-chamber membrane oxygenator |
| CN209286303U (en) * | 2018-12-07 | 2019-08-23 | 江苏美思康医疗科技有限公司 | A kind of band alternating temperature two-chamber membrane oxygenator |
-
2018
- 2018-12-07 CN CN201811493031.XA patent/CN109364315A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100272605A1 (en) * | 2009-04-23 | 2010-10-28 | Kevin Mclntosh | Radial design oxygenator with heat exchanger and pump |
| CN201510571U (en) * | 2009-09-29 | 2010-06-23 | 山东威高新生医疗器械有限公司 | Membrane type oxygenator |
| CN201978219U (en) * | 2011-02-09 | 2011-09-21 | 朱宗涛 | Flow-controllable blood extracorporeal circulation oxygenator |
| CN105828848A (en) * | 2013-12-23 | 2016-08-03 | 马里兰大学，巴尔的摩 | Blood oxygenator |
| CN203663149U (en) * | 2014-01-08 | 2014-06-25 | 陈樱 | Membrane oxygenator |
| CN105833373A (en) * | 2016-06-13 | 2016-08-10 | 北京米道斯医疗器械有限公司 | Hollow fiber membrane oxygenator and method |
| CN109364314A (en) * | 2018-12-07 | 2019-02-22 | 江苏美思康医疗科技有限公司 | A kind of two-chamber membrane oxygenator and oxygen close method |
| CN209286304U (en) * | 2018-12-07 | 2019-08-23 | 江苏美思康医疗科技有限公司 | A kind of two-chamber membrane oxygenator |
| CN209286303U (en) * | 2018-12-07 | 2019-08-23 | 江苏美思康医疗科技有限公司 | A kind of band alternating temperature two-chamber membrane oxygenator |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023284152A1 (en) * | 2021-07-14 | 2023-01-19 | 江苏赛腾医疗科技有限公司 | Membrane oxygenator having built-in filter |
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Effective date of registration: 20240929 Address after: 215000 Jinshi Building 8A-22, Shishan Road, Suzhou High tech Zone, Suzhou City, Jiangsu Province Applicant after: Suzhou Xiaoshuai Medical Equipment Co.,Ltd. Country or region after: China Address before: 225300 East side of Tai Road at the entrance of China Pharmaceutical City, Taizhou City, Jiangsu Province, and west side of G25 first floor on the north side of Xinyang Road Applicant before: JIANGSU MEISIKANG MEDICAL TECHNOLOGY Co.,Ltd. Country or region before: China |