CN109363175A - A kind of functionality integration of drinking and medicinal herbs food and preparation method thereof - Google Patents
A kind of functionality integration of drinking and medicinal herbs food and preparation method thereof Download PDFInfo
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- CN109363175A CN109363175A CN201811292911.0A CN201811292911A CN109363175A CN 109363175 A CN109363175 A CN 109363175A CN 201811292911 A CN201811292911 A CN 201811292911A CN 109363175 A CN109363175 A CN 109363175A
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- drinking
- medicinal herbs
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- herbs food
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of functional integration of drinking and medicinal herbs food, it is characterized in that, being made of the raw material of following parts by weight: 10-20 parts of rhizoma polygonati, 15-30 parts of Huang Shi, 10-15 parts of root of kirilow rhodiola, 10-20 parts of peach kernel, 5-10 parts of ginseng, 10-15 parts of Poria cocos, olive 15-30 parts of Yunnan, 10-20 parts of Flos Rosae Rugosae extract；Clinically acceptable capsule, tablet, pulvis or granule is made in the functionality integration of drinking and medicinal herbs food.The present invention using natural food materials, dual-purpose of drug and food article and can be used for the article of health food as primary raw material, it is green safe, without any preservative, synthetic dyestuff, certain range is strictly limited in dosage, finished product flavour obtained is pure, it is full of nutrition, it is without side-effects, applicant is in the article studied the article of a large amount of dual-purpose of drug and food and can be used for health food, a large amount of combination is attempted, synergistic effect is observed in said combination, especially creative is added to Yunnan olive and Flos Rosae Rugosae extract.Food prepared by the present invention significant effect in terms of strengthen immunity.
Description
Technical field
The present invention relates to field of functional food, in particular to a kind of functional integration of drinking and medicinal herbs food and preparation method thereof.
Background technique
It is immune, it is both resistance of the human body to disease, is also a kind of self-protection sexual function of body.Hypoimmunity
Body is easy to infected, and in the case, most direct performance is exactly liable to illness.Because of frequent illness, disappearing for body has been aggravated
Consumption, so generally having a delicate constitution, being apathetic, loss of appetite, sleep disturbance etc. show.Recovery time is long after illness, and
Frequent recurrent exerbation.Therefore, the immunity for enhancing human body is most important.
In recent years since, with gradually increasing for consumer healthcare's consciousness, health food is also gradually accepted by people and recognizes
It can." integration of drinking and medicinal herbs " property product is a kind of health care product of most important one.But existing health food majority is formulated effect
Indefinite, compatibility is unreasonable, takes the health food of this type, and while waste of resource, pair is even brought when some
Effect, is detrimental to health.
Summary of the invention
It is safe, without side-effects the technical problem to be solved in the present invention is to provide a kind of functional integration of drinking and medicinal herbs food, have
The effect of strengthen immunity.
In order to solve the above-mentioned technical problem, the technical solution of the present invention is as follows:
A kind of functionality integration of drinking and medicinal herbs food, is made of: 10-20 parts of rhizoma polygonati, Huang Shi 15-30 the raw material of following parts by weight
Part, 10-15 parts of root of kirilow rhodiola, 10-20 parts of peach kernel, 5-10 parts of ginseng, 10-15 parts of Poria cocos, olive 15-30 parts of Yunnan, rose are extracted
10-20 parts of object；
Clinically acceptable capsule, tablet, pulvis or granule, powder is made in the functionality integration of drinking and medicinal herbs food.
Preferably, the rhizoma polygonati is 12-15 parts, 24-27 parts of Huang Shi, 11-13 parts of root of kirilow rhodiola, 12-15 parts of peach kernel, ginseng
8-10 parts, 12-15 parts of Poria cocos, olive 24-27 parts of Yunnan, 15-18 parts of Flos Rosae Rugosae extract.
More preferably, the rhizoma polygonati is 12 parts, 24 parts of Huang Shi, 12 parts of root of kirilow rhodiola, 15 parts of peach kernel, 10 parts of ginseng, Poria cocos
12 parts, 24 parts of Yunnan olive, 18 parts of Flos Rosae Rugosae extract.
Each component involved in the present invention uses product available on the market.
The present invention also provides a kind of methods for preparing above-mentioned functional integration of drinking and medicinal herbs food, include the following steps:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Room temperature sunning is carried out to it respectively after cleaning or is dried rear spare；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component is crushed and is sieved for subsequent use respectively；
(4) each component and spare Flos Rosae Rugosae extract that crushed in parts by weight selecting step (3) according to the proportion,
It is uniformly mixed；
(5) it carries out disinfection to said mixture and sterilization processing, and customary adjuvant is added and is made clinically acceptable dose
Type to get.
Further, temperature dry in the step (1) is 30-45 DEG C.
Further, the mesh number being sieved in the step (3) is 150-200.
In each component contained by functionality integration of drinking and medicinal herbs food of the present invention:
Ginseng: being described as the superfine product of " King of Herbs " " life is mended in enriching yin, is strengthened the body resistance to consolidate the constitution " from ancient times, and sweet in flavor, slight bitter is mild-natured, returns spleen,
Lung, the heart channel of Hang-Shaoyin, containing ingredients such as ginsenoside, ginseng protein, panaxans.Ginsenoside is a kind of steroid compound, is people
Active constituent in ginseng has and inhibits cancer cell to other organ metastasis, has and removes free radical and anti-oxidant, enhancing body
The effect of immunity, fast quick-recovery constitution.
Poria cocos: Poria cocos effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, regardless of cold, temperature, wind, wet all
Disease can play its unique effects, therefore be all adjutant.Poria cocos is sweet in flavor, light, mild-natured, be used as medicine with clearing damp and promoting diuresis, beneficial spleen and
The function of stomach, antitoxic heart-soothing and sedative.Modern medicine study shows: Poria cocos can enhance body's immunity, and pachymaran has apparent anti-
Tumour and liver protecting effect.
Rhizoma polygonati: for Liliaceae Polygonatum herbaceos perennial, medicinal effects are dry rhizome.Rhizoma polygonati is supported with tonifying Qi
The effect of yin, invigorating the spleen, moistening lung, kidney-nourishing.For deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, overstrain cough
Hemoptysis, asthenia of essence and blood, soreness and weakness of waist and knees, poliosis, Heat Diabetes.Modern pharmacological studies have shown that: rhizoma polygonati has anti-aging, drop blood
Sugar, reducing blood lipid, raising and improvement are remembered, are antitumor, adjusting the effects of immune, antiviral, anti-inflammatory.
Huang Shi: contain active stronger triterpenoid saponin, flavonoids, polysaccharide, amino acid and microelement in Radix Astragali.Radix Astragali
It is a kind of important Chinese medicine tonifying Qi key medicine.Modern studies have found that this " tonifying Qi " effect of Radix Astragali is mainly manifested in enhancing and is immunized
Power improves heart function and blood microcirculation etc., can treat coronary heart disease, heart failure, ischemic cerebrovascular disease.
Root of kirilow rhodiola: there is qi and activate blood circulation, the function of promotes blood circulation and relievings asthma.It is mainly used for qi deficiency to blood stasis, chest impediment and cardialgia, hemiplegia,
Burnout asthma.
Peach kernel: vitamin B and vitamin E rich in can prevent cell senescence, have brain tonic, enhancing memory and
The effect of anti-aging.
Yunnan olive: also known as Yunnan emblic, it is the fruit of Euphorbiaceae machaka or magaphanerophytes' emblic.Yunnan olive fruit
Juice unique flavor, it is full of nutrition, other than containing amino acid and microelement, more importantly its Vc content is high, and due to
The protection of flavones and tannin, the retention ratio of its Vc is still up to 72% after Yunnan olive is processed, significantly larger than other fruits and vegetables.
Fruit medicine has clearing heat, relieving sore-throat, moistening lung for removing phlegm, the effect of promoting the production of body fluid to quench thirst.Modern medicine study shows: Yunnan olive has antioxygen
The effects of changing, removing free radical, is antitumor, anti-aging.
Flos Rosae Rugosae extract: containing various chemical components in rose, such as fragrance alcohol, aldehyde, fatty acid, phenol and contain essence
Oil and rouge.Oxidation-resistant active ingredient in rose, with the extremely strong ability for removing free radical, for anti-aging, enhancing
Immunity, protection skin, beautifying face and moistering lotion significant effect.
The present invention by monarch in mentioned component, minister, help, be allowed between synergistic effect so that the effective medicine component of monarch drug in a prescription can be with
Under the booster action of ministerial drug, promote the ingredient for reinforcing the performance of monarch drug in a prescription drug effect in monarch drug in a prescription and ministerial drug that can preferably act on trouble
Portion, to effectively absorb for human body, further ensuring the effective medicine component of monarch drug in a prescription can go directly affected part after fully absorbing, and reach
Ease up the effect of physical fatigue to strengthen immunity, is effectively improved sub-health state.
The beneficial effects of the present invention are:
(1) present invention using natural food materials, dual-purpose of drug and food article and can be used for the article of health food as primary raw material, it is green
Color safety is free of any preservative, synthetic dyestuff, is strictly limited in certain range in dosage, and finished product flavour obtained is pure,
It is full of nutrition, it is without side-effects, for promoting immunity with preferable effect.
(2) functional integration of drinking and medicinal herbs food of the present invention, applicant is in the article for studying a large amount of dual-purpose of drug and food and can
For having attempted a large amount of combination in the article of health food, synergistic effect, especially creativeness are observed in said combination
Be added to Yunnan olive and Flos Rosae Rugosae extract.Food prepared by the present invention has the extremely strong ability for removing free radical, is increasing
Significant effect in terms of strong immunity.
Specific embodiment
Below with reference to embodiment, specific embodiments of the present invention will be further explained.It should be noted that right
It is used to help understand the present invention in the explanation of these embodiments, but and does not constitute a limitation of the invention.In addition, being retouched below
Technical characteristic involved in each embodiment of the present invention stated can be combined with each other as long as they do not conflict with each other.
Embodiment 1
A kind of functionality integration of drinking and medicinal herbs food, is made of the raw material of following parts by weight: 10 parts of rhizoma polygonati, 15 parts of Huang Shi, red
13 parts of red-spotted stonecrop, 10 parts of peach kernel, 8 parts of ginseng, 15 parts of Poria cocos, 30 parts of Yunnan olive, 15 parts of Flos Rosae Rugosae extract；
Functionality integration of drinking and medicinal herbs food of the present invention is made by the steps to obtain:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Carry out room temperature sunning after cleaning to it respectively, drying to moisture content is spare after being lower than 2%；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component is crushed and is sieved with 100 mesh sieve respectively, spare；
(4) spare rose in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Flower extract is uniformly mixed；
(5) ultraviolet disinfection and sterilization processing are carried out to said mixture, and be added customary adjuvant be made pulvis to get.
Embodiment 2
A kind of functionality integration of drinking and medicinal herbs food, is made of the raw material of following parts by weight: 20 parts of rhizoma polygonati, 27 parts of Huang Shi, red
10 parts of red-spotted stonecrop, 12 parts of peach kernel, 5 parts of ginseng, 13 parts of Poria cocos, 15 parts of Yunnan olive, 10 parts of Flos Rosae Rugosae extract；
Functionality integration of drinking and medicinal herbs food of the present invention is made by the steps to obtain:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Carry out room temperature sunning after cleaning to it respectively, drying to moisture content is spare after being lower than 2%；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component crushes respectively and crosses 150 meshes, spare；
(4) spare rose in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Flower extract is uniformly mixed；
(5) ultraviolet disinfection and sterilization processing are carried out to said mixture, and be added customary adjuvant be made tablet to get.
Embodiment 3
A kind of functionality integration of drinking and medicinal herbs food, is made of the raw material of following parts by weight: 12 parts of rhizoma polygonati, 24 parts of Huang Shi, red
12 parts of red-spotted stonecrop, 15 parts of peach kernel, 10 parts of ginseng, 12 parts of Poria cocos, 24 parts of Yunnan olive, 18 parts of Flos Rosae Rugosae extract；
Functionality integration of drinking and medicinal herbs food of the present invention is made by the steps to obtain:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Carry out room temperature sunning after cleaning to it respectively, drying to moisture content is spare after being lower than 2%；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component is crushed and is sieved with 100 mesh sieve respectively, spare；
(4) spare rose in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Flower extract is uniformly mixed；
(5) ultraviolet disinfection and sterilization processing are carried out to said mixture, and customary adjuvant is added, tablet, every slice weight is made
0.5g to get.
Embodiment 4
A kind of functionality integration of drinking and medicinal herbs food, is made of the raw material of following parts by weight: 15 parts of rhizoma polygonati, 30 parts of Huang Shi, red
15 parts of red-spotted stonecrop, 20 parts of peach kernel, 9 parts of ginseng, 10 parts of Poria cocos, 27 parts of Yunnan olive, 20 parts of Flos Rosae Rugosae extract；
Functionality integration of drinking and medicinal herbs food of the present invention is made by the steps to obtain:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Carry out room temperature sunning after cleaning to it respectively, drying to moisture content is spare after being lower than 2%；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component crushes respectively and crosses 120 meshes, spare；
(4) spare rose in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Flower extract is uniformly mixed；
(5) ultraviolet disinfection and sterilization processing are carried out to said mixture, and be added customary adjuvant be made tablet to get.
Embodiment 5
A kind of functionality integration of drinking and medicinal herbs food, is made of the raw material of following parts by weight: 13 parts of rhizoma polygonati, 26 parts of Huang Shi, red
12 parts of red-spotted stonecrop, 10 parts of peach kernel, 10 parts of ginseng, 12 parts of Poria cocos, 24 parts of Yunnan olive, 20 parts of Flos Rosae Rugosae extract；
Functionality integration of drinking and medicinal herbs food of the present invention is made by the steps to obtain:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and
Carry out room temperature sunning after cleaning to it respectively, drying to moisture content is spare after being lower than 2%；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component crushes respectively and crosses 150 meshes, spare；
(4) spare rose in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Flower extract is uniformly mixed；
(5) ultraviolet disinfection and sterilization processing are carried out to said mixture, and be added customary adjuvant be made capsule to get.
Strengthen immunity experiment:
Experimental animal: weight 18-22g, 6-8 week old inbred mouse 60 is chosen, male and female respectively account for half.
Experimental method: testing and set a blank control group and basic, normal, high three dosage groups, and every group 15.It chooses and implements
Gained tablet sample, is taken twice daily according to adult in example 3, and each one, adult weight is calculated by 60kg, and equivalent dosage is
33mg/kg BW.With 5 times of adult human dose, 10 times, 20 times, i.e. 165mg/kg BW, 330mg/kg BW, 660mg/kg BW add
Distilled water carries out feeding test mice to 200ml, while control group is given equal amount of distilled water and fed.Twice daily, continuous 30 days.
Testing index: the following terms index: 1, internal organs/weight ratio is measured respectively within 24 hours after last is fed；2, tardy
Allergic reaction type (toes thicken method)；3, the measurement of half hemolytic value (HC50)；4, carbonic clearance index；5, mouse peritoneal macrophage is thin
Endocytosis bites the influence of flesh red blood cell；6, NK cell activity influences.
Experimental result:
1, each group mice organs/weight ratio situation
1 sample of table is to mice organs/weight ratio influence (means standard deviation)
| Group | Spleen weight/weight | Chest gland weight/weight | P value |
| Control group | 38.28±3.75 | 19.36±3.57 | — |
| Low dose group | 43.06±4.50 | 22.15±3.43 | P > 0.05 |
| Middle dose group | 48.28±4.66 | 24.22±3.39 | P < 0.05 |
| High dose group | 50.71±5.21 | 25.07±3.64 | P < 0.05 |
As can be seen from Table 1, the tested material of orally administration mouse various dose is after 30 days, each dosage group thymus gland/weight
Ratio is both greater than control group, wherein internal organs/weight ratio of middle and high dosage group is noticeably greater than control group, shows that the sample has and promotees
The effect increased into mouse immune organ.
2, influence of the sample to mouse delayed allergy (toes thicken method)
Influence (means standard deviation) of 2 sample of table to mouse delayed allergy (toes thicken method)
| Group | Attack front and back toes thickness difference (mm) | P value |
| Control group | 0.41±0.07 | — |
| Low dose group | 0.46±0.07 | P > 0.05 |
| Middle dose group | 0.50±0.06 | P < 0.05 |
| High dose group | 0.56±0.06 | P < 0.05 |
3, influence of the sample to mouse half hemolytic value (HC50)
Influence (means standard deviation) of 3 sample of table to mouse half hemolytic value (HC50)
From table 3 it is observed that the half hemolytic value (HC50) of each dosage group is above control class value, and middle and high dosage
There is significant difference in group, and difference (P < 0.05) is statistically significant compared with the control.Show that sample has and increases mouse half
The effect of hemolysis value (HC50).
4, the influence that sample tests mouse carbonic clearance
The influence (means standard deviation) that 4 sample of table tests mouse carbonic clearance
| Group | Phagocytic index | P value |
| Control group | 4.73±0.65 | — |
| Low dose group | 5.02±1.05 | P > 0.05 |
| Middle dose group | 6.25±1.17 | P < 0.05 |
| High dose group | 6.37±1.31 | P < 0.05 |
Can take a fancy to from table 4, the phagocytic index of each dosage group is all larger than control group, wherein middle and high dosage group with compare
The phagocytic index of group shows that the sample has the function of increasing the phagocytic index of mouse there are significant difference (P < 0.05).
5, influence of the sample to Turnover of Mouse Peritoneal Macrophages phagocytosis flesh red blood cell
Influence (means standard deviation) of 5 sample of table to Turnover of Mouse Peritoneal Macrophages phagocytosis flesh red blood cell
| Group | Phagocytic percentage (%) | Phagocytic index | P value |
| Control group | 13.82±1.44 | 0.17±0.04 | — |
| Low dose group | 14.77±1.254 | 0.19±0.05 | P > 0.05 |
| Middle dose group | 17.22±1.60 | 0.23±0.04 | P < 0.05 |
| High dose group | 18.35±1.95 | 0.26±0.05 | P < 0.05 |
As can be seen from Table 5, each dosage group compared with the control group of sample, phagocytic percentage, phagocytic index have
Risen, wherein middle and high dosage group has significant difference (P < 0.05) compared with the control, shows that the sample has increase small
Mouse peritoneal macrophage swallows the phagocytic rate of flesh red blood cell and the effect of phagocytic index.
6, sample is to NK cells in mice activity influence
6 sample of table is to NK cells in mice activity influence (means standard deviation)
| Group | NK cell activity (%) | P value |
| Control group | 27.6±7.5 | — |
| Low dose group | 30.7±8.6 | P > 0.05 |
| Middle dose group | 36.6±7.7 | P < 0.05 |
| High dose group | 40.25±7.3 | P < 0.05 |
As can be seen from Table 6, NK cytoactive detection shows that middle and high dosage group NK cell activity is significantly higher than control
Group, and difference (P < 0.05) is statistically significant.
Conclusion:
By tablet sample prepared by the raw material proportioning and method of embodiment 3, (divided with 165,330,660mg/kg BW respectively
Be not equivalent to 5,10,20 times of human body recommended amounts) dosage to mouse continuous gavage 30 days, mouse spleen, thymus gland can not only be improved
Internal organs/weight ratio, promote mouse half hemolytic value (HC50) content, be respectively increased mouse carbonic clearance test phagocytic index and
The phagocytic rate of phagocytosis test, phagocytic index.It is above-mentioned the experimental results showed that the sample have the function of enhance animal immunizing power.
Above in conjunction with the embodiments and experimental example the embodiments of the present invention are described in detail, but the present invention is not limited to
Described embodiment.For a person skilled in the art, right in the case where not departing from the principle of the invention and spirit
These embodiments carry out a variety of change, modification, replacement and modification, still fall in protection scope of the present invention.
Claims (7)
1. a kind of functionality integration of drinking and medicinal herbs food, which is characterized in that be made of the raw material of following parts by weight: 10-20 parts of rhizoma polygonati,
15-30 parts of Huang Shi, 10-15 parts of root of kirilow rhodiola, 10-20 parts of peach kernel, 5-10 parts of ginseng, 10-15 parts of Poria cocos, olive 15-30 parts of Yunnan, rose
Rare flower extract 10-20 parts；
Clinically acceptable capsule, tablet, pulvis or granule is made in the functionality integration of drinking and medicinal herbs food.
2. a kind of functional integration of drinking and medicinal herbs food according to claim 1, which is characterized in that the rhizoma polygonati is 12-15 parts,
24-27 parts of Huang Shi, 11-13 parts of root of kirilow rhodiola, 12-15 parts of peach kernel, 8-10 parts of ginseng, 12-15 parts of Poria cocos, olive 24-27 parts of Yunnan, rose
Rare flower extract 15-18 parts.
3. a kind of functional integration of drinking and medicinal herbs food according to claim 2, which is characterized in that the rhizoma polygonati is 12 parts, yellow
24 parts of family name, 12 parts of root of kirilow rhodiola, 15 parts of peach kernel, 10 parts of ginseng, 12 parts of Poria cocos, 24 parts of Yunnan olive, 18 parts of Flos Rosae Rugosae extract.
It prepares a kind of method of functionality integration of drinking and medicinal herbs food, feature described in any one of claims 1 to 3 4. a kind of and exists
In including the following steps:
(1) rhizoma polygonati, Huang Shi, root of kirilow rhodiola, peach kernel, ginseng, Poria cocos and Yunnan olive are chosen, is cleaned respectively, and cleaning
It carries out room temperature sunning to it respectively afterwards or is dried rear spare；
(2) Flos Rosae Rugosae extract is spare；
(3) by treated in step (1), each component is crushed and is sieved for subsequent use respectively；
(4) spare rose mentions in each component and step (2) that crushed in parts by weight selecting step (3) according to the proportion
Object is taken, is uniformly mixed；
(5) it carries out disinfection to said mixture and sterilization processing, and customary adjuvant is added, clinically acceptable dosage form is made, i.e.,
?.
5. a kind of method for preparing functional integration of drinking and medicinal herbs food according to claim 4, it is characterised in that: the step
(1) dry temperature is 30-45 DEG C in.
6. a kind of method for preparing functional integration of drinking and medicinal herbs food according to claim 4, it is characterised in that: the step
(3) mesh number being sieved in is 150-200.
7. a kind of functional integration of drinking and medicinal herbs food that the method according to claim 11 is prepared.
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Application publication date: 20190222 |