CN109362759A - A kind of bactericidal composition and its application of containing chlorine fluorine ether bacterium azoles and pyraclostrobin - Google Patents
A kind of bactericidal composition and its application of containing chlorine fluorine ether bacterium azoles and pyraclostrobin Download PDFInfo
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- CN109362759A CN109362759A CN201811524124.4A CN201811524124A CN109362759A CN 109362759 A CN109362759 A CN 109362759A CN 201811524124 A CN201811524124 A CN 201811524124A CN 109362759 A CN109362759 A CN 109362759A
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- Prior art keywords
- pyraclostrobin
- bacterium azoles
- ether bacterium
- bactericidal composition
- fluorine
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title claims abstract description 152
- 241000894006 Bacteria Species 0.000 title claims abstract description 87
- 150000003851 azoles Chemical class 0.000 title claims abstract description 72
- HXELGNKCCDGMMN-UHFFFAOYSA-N [F].[Cl] Chemical compound [F].[Cl] HXELGNKCCDGMMN-UHFFFAOYSA-N 0.000 title claims abstract description 67
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 title claims abstract description 66
- 239000005869 Pyraclostrobin Substances 0.000 title claims abstract description 65
- 239000000203 mixture Substances 0.000 title claims abstract description 55
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 26
- 239000000575 pesticide Substances 0.000 claims abstract description 18
- 239000003814 drug Substances 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 239000012752 auxiliary agent Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000003921 oil Substances 0.000 claims description 3
- 239000000375 suspending agent Substances 0.000 claims description 3
- 239000002518 antifoaming agent Substances 0.000 claims description 2
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 239000000839 emulsion Substances 0.000 claims description 2
- 239000000945 filler Substances 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000004530 micro-emulsion Substances 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- 239000000080 wetting agent Substances 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000004563 wettable powder Substances 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 12
- 206010059866 Drug resistance Diseases 0.000 abstract description 11
- 244000052769 pathogen Species 0.000 abstract description 9
- 230000001717 pathogenic effect Effects 0.000 abstract description 9
- 239000000126 substance Substances 0.000 abstract description 5
- 230000003111 delayed effect Effects 0.000 abstract description 3
- 230000009467 reduction Effects 0.000 abstract description 3
- 230000002045 lasting effect Effects 0.000 abstract description 2
- 231100000053 low toxicity Toxicity 0.000 abstract description 2
- 241000234295 Musa Species 0.000 description 15
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 15
- 238000012360 testing method Methods 0.000 description 13
- 201000010099 disease Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 241000196324 Embryophyta Species 0.000 description 9
- 239000002609 medium Substances 0.000 description 6
- 230000003449 preventive effect Effects 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 150000003217 pyrazoles Chemical class 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 5
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 229910052801 chlorine Inorganic materials 0.000 description 5
- 239000000460 chlorine Substances 0.000 description 5
- 229910052731 fluorine Inorganic materials 0.000 description 5
- 239000011737 fluorine Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 150000002148 esters Chemical class 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 230000003993 interaction Effects 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 239000005800 Kresoxim-methyl Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- ZOTBXTZVPHCKPN-HTXNQAPBSA-N kresoxim-methyl Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=CC=C1C ZOTBXTZVPHCKPN-HTXNQAPBSA-N 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- 206010039509 Scab Diseases 0.000 description 2
- ABUGVBRDFWGJRD-CHOYNLESSA-N [9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]-2-(2,4-dinitrophenyl)sulfanylpurin-6-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](C)O[C@H]1N1C2=NC(SC=3C(=CC(=CC=3)[N+]([O-])=O)[N+]([O-])=O)=NC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C2N=C1 ABUGVBRDFWGJRD-CHOYNLESSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000003470 mitochondria Anatomy 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 230000000361 pesticidal effect Effects 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- ZMYFCFLJBGAQRS-IRXDYDNUSA-N (2R,3S)-epoxiconazole Chemical compound C1=CC(F)=CC=C1[C@@]1(CN2N=CN=C2)[C@H](C=2C(=CC=CC=2)Cl)O1 ZMYFCFLJBGAQRS-IRXDYDNUSA-N 0.000 description 1
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 description 1
- MREIFUWKYMNYTK-UHFFFAOYSA-N 1H-pyrrole Chemical class C=1C=CNC=1.C=1C=CNC=1 MREIFUWKYMNYTK-UHFFFAOYSA-N 0.000 description 1
- JERZEQUMJNCPRJ-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(C)CN1C=NC=N1 JERZEQUMJNCPRJ-UHFFFAOYSA-N 0.000 description 1
- 241001157813 Cercospora Species 0.000 description 1
- 102100025287 Cytochrome b Human genes 0.000 description 1
- 102000019265 Cytochrome c1 Human genes 0.000 description 1
- 108010075028 Cytochromes b Proteins 0.000 description 1
- 108010007528 Cytochromes c1 Proteins 0.000 description 1
- 239000005767 Epoxiconazole Substances 0.000 description 1
- 239000005784 Fluoxastrobin Substances 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 231100000674 Phytotoxicity Toxicity 0.000 description 1
- 239000005822 Propiconazole Substances 0.000 description 1
- 241000184297 Pseudocercospora musae Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000017858 demethylation Effects 0.000 description 1
- 238000010520 demethylation reaction Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 230000008686 ergosterol biosynthesis Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000005078 fruit development Effects 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 239000002420 orchard Substances 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical group CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention discloses bactericidal composition and its application of a kind of containing chlorine fluorine ether bacterium azoles and pyraclostrobin, belongs to Techniques For Chemical Control field.The effective component of the bactericidal composition is fluorine chlorine ether bacterium azoles and pyraclostrobin, the weight part ratio of fluorine chlorine ether bacterium azoles and pyraclostrobin is 9:1~1:9, and weight percent of the weight summation of fluorine chlorine ether bacterium azoles and pyraclostrobin in bactericidal composition is 20%~50%.The present invention has efficient, low toxicity, low-residual, lasting period long the bactericidal composition that fluorine chlorine ether bacterium azoles and pyraclostrobin mixture obtain, to crop safety, environmentally friendly feature；There are significant synergy and addition to sigatoka and its pathogen, has preferable control efficiency in field；And pathogen drug resistance can effectively be delayed to generate, pesticide input amount is reduced, achievees the purpose that pesticide reduction.
Description
Technical field
The present invention relates to the Prevention Techniques of plant disease, belong to Techniques For Chemical Control field, contain more particularly, to one kind
The bactericidal composition and its application of fluorine chlorine ether bacterium azoles and pyraclostrobin.The bactericidal composition is fluorine chlorine ether bacterium azoles and pyrazoles ether bacterium
Ester is that the pesticide sterilizing of effective component combines, for preventing and treating sigatoka and its using technology.
Background technique
Sigatoka is the general name of banana leaf diseases, is one of disease important in banana production, in south China Jiao Qu
Occur generally, to endanger heavier.Sigatoka frequent species have: Cercospora leaf spot, the mould leaf spot of small Dou Shi, the mould leaf of dark double spores
Most universal, harm occurs for pinta, the mould leaf spot of curved spore etc. most in Guangdong Province with tail spore bacterium (Cercospora musae) leaf spot
Seriously, the disease main harm Leaf of banana, causes that blade is withered, photosynthesis significantly reduces, and leads to plant early ageing, so that influencing
Fruit development enriches, and the diseased plant underproduction is the important disease urgently prevented and treated in banana production up to 30%~50%.Currently, chemistry is anti-
It controls and is still prevention and control sigatoka effective method the most direct, the routine medicine such as propiconazole, epoxiconazole, Fluoxastrobin, benzoxazole
Agent has preferable control efficiency to sigatoka bacterium, but with the long-time service of conventional dose, pathogen inevitably occurs
Drug resistance.Screening novel built medicament reduces Pesticide use number, reaches the mesh of pesticide reduction to pathogen drug resistance is delayed
Be of great significance.
Fluorine chlorine ether bacterium azoles (Mefentrifluconazole) be a kind of wide spectrum, efficiently, interior suction, have and root out and protect work
Fungicide belongs to sterol demethylation inhibitor class, and the mechanism of action is to prevent the biosynthesis of ergosterol, inhibits cell
Grow and eventually lead to the collapsing of cell membrane.Unlike widely used triazole bactericidal agent, fluorine chlorine ether bacterium azoles contains different
Propyl alcohol structure, it is possible to reduce pathogen mutation delays the drug resistance of pathogen, helps that the resistance of fungicide is delayed to generate and send out
Exhibition.
Pyraclostrobin (Pyraclostrobine) is methoxy acrylic wide-spectrum bactericide, is a kind of mitochondria
Respiration inhibitor prevents mitochondria from producing by preventing electron transmission between cytochrome b and c1 that mitochondrial respiratory is inhibited to act on
Energy required for raw and offer cell eubolism, eventually leads to cell death.Pyraclostrobin has stronger inhibition disease
Bacterium spore germination ability has good inhibiting effect to mycelia growth in blade, has preventive and therapeutic action to crop disease.
Currently, there are the risks of drug resistance for the prevention and treatment of sigatoka, the third ring of conventional dose of sigatoka is such as prevented and treated
The resistance of azoles generally occurs in some areas, and banana peasant arbitrarily increases dosage, increases times for spraying, accelerates the hair of drug resistance
It is raw.With a large amount of uses of single medicament, though it is foreseeable that pathogen drug resistance will rapid increase, drug resistance once big face
Product occurs, and will be unable to control.A main method for solving resistance, is exactly the rotation medication by way of mixture.
Summary of the invention
In order to overcome the disadvantages and deficiencies of the prior art, the primary purpose of the present invention is that providing a kind of containing chlorine fluorine ether bacterium azoles
With the bactericidal composition of pyraclostrobin.
Another object of the present invention is to provide answering for the bactericidal composition of above-mentioned containing chlorine fluorine ether bacterium azoles and pyraclostrobin
With.
The present invention to be solved be current chemical control sigatoka drug resistance improve year by year, control efficiency it is undesirable
Technical problem provides a kind of pesticide sterilizing combination for efficiently preventing and treating sigatoka, while providing the use of the composition
Technology, and the application in sigatoka prevention and treatment.
The purpose of the invention is achieved by the following technical solution:
The present invention provide it is a kind of efficiently, low toxicity, low-residual, lasting period it is long, to crop safety, environment amenable pesticide group
Close object.Present invention applicant has found fluorine chlorine ether bacterium azoles and pyrazoles ether by a large amount of indoor bioassay and field control effectiveness test
Bacterium ester after mixture, has significant synergy and addition to sigatoka and its pathogen in certain proportion.In above-mentioned hair
It on the basis of existing, is further furtherd investigate, forms technical solution of the present invention, a kind of containing chlorine fluorine ether bacterium azoles and pyrazoles ether bacterium
The bactericidal composition of ester, effective component are fluorine chlorine ether bacterium azoles and pyraclostrobin, the weight of fluorine chlorine ether bacterium azoles and pyraclostrobin
Number ratio is 9:1~1:9, preferably 3:1~1:3；More preferably 3:1~1:1.The weight of fluorine chlorine ether bacterium azoles and pyraclostrobin
Measuring weight percent of the summation in bactericidal composition is 20%~50%.
Bactericidal composition of the invention can according to methods well known to those skilled in the art, with fluorine chlorine ether bacterium azoles and pyrazoles ether
Bacterium ester is that any one dosage form allowed on pesticide is made in principle active component and auxiliary agent.The dosage form is missible oil, wettable
Pulvis, suspending agent, aqueous emulsion, microemulsion or water dispersion granule.Bactericidal composition of the invention also contains preparation pesticidal preparations
Required auxiliary element (auxiliary agent), including emulsifier, wetting agent, stabilizer, dispersing agent, thickener, defoaming agent, antifreezing agent, fill out
One or more of mixing such as agent, filler, medium are filled, is known substance, is common various auxiliary agents in pesticidal preparations, according to not
It can be varied, be not particularly limited with situation.
The present invention also provides the bactericidal compositions of a kind of containing chlorine fluorine ether bacterium azoles and pyraclostrobin to prevent and treat Banana Leaf in preparation
Application on pinta drug.
The present invention has the following advantages and effects with respect to the prior art:
(1) fluorine chlorine ether bacterium azoles and pyraclostrobin mixture have significant addition to Banana Leaf plaque, field have compared with
Good control efficiency；
(2) fluorine chlorine ether bacterium azoles and pyraclostrobin mixture can effectively delay pathogen drug resistance to generate, and reduce pesticide investment
Amount, achievees the purpose that pesticide reduction.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
In embodiment, unless otherwise stated, all percentages are weight percentage.
Different types of pesticide active ingredient is subjected to mixture, is use cost in current solution pesticide single dose application process
And a kind of effective means of the problems such as drug resistance.After different types of pesticide active ingredient mixture, three kinds of effects are typically exhibited
Type, i.e. addition, synergistic effect, antagonism.Present invention applicant on the basis of a large amount of indoor bioassay are tested,
It was found that fluorine chlorine ether bacterium azoles and pyraclostrobin are made within the scope of certain mixed ratio, to sigatoka bacterium with significant addition
With.
1, Assays Example 1:
The indoor toxicity test of fluorine chlorine ether bacterium azoles and pyraclostrobin and its compounding to sigatoka bacterium.
(1) medicament mixture:
98% fluorine chlorine ether bacterium azoles raw medicine of acetone solution and 99% pyraclostrobin raw medicine are first used, single dose mother liquor is respectively prepared.
According to preliminary experiment as a result, on the basis of above-mentioned single dose mother liquor, appropriate two raw medicines are configured to the mixed of five kinds of different ratios
Agent, then with the dilution of the aqueous solution of the Tween 80 containing 0.1% to be configured to 6 series mass strength solutions respectively stand-by.Fluorine chlorine ether
Bacterium azoles is diluted to 0.1 μ g/mL, 0.05 μ g/mL, 0.01 μ g/mL, 0.005 μ g/mL, 0.0025 μ g/mL, 0.001 μ g/mL；Pyrazoles
Kresoxim-methyl is diluted to 20 μ g/mL, 10 μ g/mL, 5 μ g/mL, 1 μ g/mL, 0.5 μ g/mL, 0.25 μ g/mL；Fluorine chlorine ether bacterium azoles and pyrazoles
Five kinds of different ratios of kresoxim-methyl (effective component weight ratio be 9:1,3:1,1:1,1:3,1:9) be diluted to respectively 0.25 μ g/mL,
0.1μg/mL、0.05μg/mL、0.025μg/mL、0.01μg/mL、0.005μg/mL。
(2) test method:
It is measured using dry mycelial weight method, quantitative PS culture solution (i.e. liquid Ma Ling is added by various dose for reagent agent
Potato sucrose culture medium) in, it is configured to the drug containing fluid nutrient medium of series of concentrations.2 single doses and 5 mixture formulas are configured to respectively
The drug containing fluid nutrient medium of 6 various concentrations, every concentration processing are all provided with 4 repetitions.It under aseptic conditions, will be on PSA plate
Cultured sigatoka bacterium bacterium colony is chosen and is cut into the mycelia block of about 1 × 1 × 1mm with sterilizing blade, and each triangular flask connects
Enter 6 mycelia blocks, quantitatively accesses in configured good drug containing fluid nutrient medium, under 26.0 DEG C, 130r/min non-illuminated conditions
Constant-temperature shaking culture.Mycelium was filtered by vacuum with filter paper and is collected after 17 days by sigatoka bacterium shaken cultivation, and was placed it in
In electric heating constant-temperature blowing drying box 60 DEG C of drying several hours to constant weight, then with electronic balance weighing dry mycelial weight, with blank pair
According to comparing, the fungistatic effect that each chemicals treatment grows sigatoka bacterium mycelia is calculated, using DPS data processing system to examination
Result is tested to carry out significance difference analysis and calculate the EC of test medicine50And EC90。
(3) test result:
Test result shows that fluorine chlorine ether bacterium azoles and pyraclostrobin mixture have preferably the mycelia growth of sigatoka bacterium
Inhibitory effect, total effective component concentration is in 0.25 μ g/mL, fluorine chlorine ether bacterium azoles: pyraclostrobin (9:1), fluorine chlorine ether bacterium azoles:
Pyraclostrobin (3:1), fluorine chlorine ether bacterium azoles: pyraclostrobin (1:1), fluorine chlorine ether bacterium azoles: pyraclostrobin (1:3), fluorine chlorine ether
Bacterium azoles: pyraclostrobin (1:9), their average inhibitory effect respectively reaches 99.84%, 99.66%, 98.84%,
98.61% and 98.57%.The mixture EC of fluorine chlorine ether bacterium azoles and pyraclostrobin mixture different ratio50(ob)It is followed successively by 0.0019 μ
G/mL, 0.0021 μ g/mL, 0.0023 μ g/mL, 0.0047 μ g/mL, 0.0153 μ g/mL, EC90(ob)Respectively 0.0175 μ g/mL,
0.0205 μ g/mL, 0.027 μ g/mL, 0.0414 μ g/mL, 0.0598 μ g/mL (being shown in Table 1).
Fluorine chlorine ether bacterium azoles and pyraclostrobin different proportion mixture are calculated theoretically according to Wadley (1945,1967) formula
EC50(th), and the EC with actual observation50(ob)Compare, calculates the synergism value (SR) of the two interaction.SR value is 0.5~1.5,
Indicate addition；Value > 1.5 SR indicate synergy (collaboration) effect；Value < 0.5 SR indicates antagonism.Fluorine chlorine ether bacterium azoles: pyrrole
Azoles kresoxim-methyl (9:1), fluorine chlorine ether bacterium azoles: pyraclostrobin (3:1), fluorine chlorine ether bacterium azoles: pyraclostrobin (1:1), fluorine chlorine ether bacterium
Azoles: pyraclostrobin (1:3), fluorine chlorine ether bacterium azoles: pyraclostrobin (1:9), 5 different proportion mixture Degree of interaction SR values
Respectively 0.93,1.01,1.38,1.32 and 0.96 illustrate this 5 proportion mixtures to Banana Leaf between 0.5~1.5
Pinta bacterium shows as addition (being shown in Table 1).
The toxicity test result of 1 fluorine chlorine ether bacterium azoles of table and pyraclostrobin and different ratio to sigatoka bacterium
Note: 1.EC50(ob)And EC90(ob)To automatically analyze gained using computer data processing system；2.X- represents logarithm
Concentration, Y- represent inhibiting rate probit value.
Note: A, B respectively represents 98% fluorine chlorine ether bacterium azoles raw medicine and 99% pyraclostrobin raw medicine；
A, b respectively represents the percentage composition of fluorine chlorine ether bacterium azoles and pyraclostrobin in mixture, and unit is percentage (%)；
SR represents Degree of interaction.
As can be seen from the test results, fluorine chlorine ether bacterium azoles: pyraclostrobin mixture is 9:1~1:9 in weight amount portion rate
Between, 5 different proportion mixture Degree of interaction SR values show apparent addition and make between 0.5~1.5
With.Fluorine chlorine ether bacterium azoles and pyraclostrobin mixture have reasonability and feasibility, and further crop field is worth to promote and apply.
2, field control effectiveness test embodiment 1:
(1) test site: the Guangdong Province Longmen County town the Yong Han village San Keng
(2) experimental condition: banana (Brazilian variety) is that 2 years any of several broadleaf plants stay bud cultivating and growing, and any of several broadleaf plants field gesture is flat, and water level is medium,
Soil fertility is preferable, and planting density is about 120 plants/667m2, each phase fertilizer and water management of banana, control of insect measure belong to local medium
It is horizontal.
(3) test method: test 30% fluorine chlorine ether bacterium azole suspending agent of medicament, 25% pyraclostrobin missible oil set 6 altogether
Processing, 4 repetitions of every processing, 1 cell of every repetition amount to 24 cells, and every cell amounts to 120 plants for 5 plants of banana of examination.Weight
Again it counts: 4 times.Orchard complete stool sprays uniformly spray blade face and the blade back of banana, are sprayed onto until blade face drips, every plant of liquid volume
0.8 liter, formulation rate is about 1440 liters/hectare.It sprays the morbidity at the beginning of banana lower blade, was administered 1 time every 10-15 days,
It sprays 3 times altogether.
(4) investigation method: the normal number of sheets, the sick number of sheets and sick grade are investigated, the average disease of calculating refers to and average preventive effect, and uses DMRT
Method carries out significance difference analysis to test result.
Sick leaf stage division: 0 grade: disease-free spot；1 grade: lesion area accounts for 5% or less entire blade area；3 grades: scab
Area accounts for the 6%-15% of entire blade area；5 grades: lesion area accounts for the 16%-25% of entire blade area；7 grades: scab face
Product accounts for the 26%-50% of entire blade area；9 grades: lesion area accounts for 51% or more of entire blade area.
Drug effect calculation method:
Each processing disease index and average preventive effect are calculated, and significance difference analysis is carried out to test result with DMRT method.
(5) test result:
From Table 2, it can be seen that 10 days after application 3 times, fluorine chlorine ether bacterium azoles (150mg/kg), pyraclostrobin (167mg/
It kg is respectively) 77.47%, 72.56% to the preventive effect of sigatoka.Fluorine chlorine ether bacterium azoles: pyraclostrobin (3:1), fluorine chlorine ether
Bacterium azoles: pyraclostrobin (1:1), fluorine chlorine ether bacterium azoles: 3 composition pesticides of pyraclostrobin (1:3) use effective component
The average preventive effect of 160mg/kg is apparently higher than pyraclostrobin single dose, fluorine chlorine ether bacterium azoles: pyraclostrobin (3:1), fluorine chlorine ether bacterium
Azoles: 2 composition pesticides of pyraclostrobin (1:1) are apparently higher than fluorine chlorine ether bacterium using the average preventive effect of effective component 160mg/kg
Azoles single dose.It is observed during testing, fluorine chlorine ether bacterium azoles is handled to banana tender leaf not with pyraclostrobin mixture three for examination concentration
See phytotoxicity phenomenon, Leaf of banana growth is normal.
The result of field embodiment sufficiently shows after present composition fluorine chlorine ether bacterium azoles and pyraclostrobin mixture to anti-
Sigatoka is controlled with apparent synergistic effect, the control efficiency of the composition is excellent, fluorine chlorine ether bacterium azoles: pyraclostrobin
(1:1) and fluorine chlorine ether bacterium azoles: the control efficiency of pyraclostrobin (3:1) is superior to single dose kind, agricultural application in have compared with
Good application prospect.Drug effect can be improved for preventing and treating sigatoka in the present composition, reduces the dosage of pesticide, subtracts
Few times for spraying, reduces drug cost, reduces pesticide to the adverse effect of ecological environment, is worth further genralrlization.
2 fluorine chlorine ether bacterium azoles pyraclostrobin mixture of table prevents and treats sigatoka field control effectiveness test result
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (8)
1. a kind of bactericidal composition of containing chlorine fluorine ether bacterium azoles and pyraclostrobin, it is characterised in that: the bactericidal composition has
Ingredient is imitated as fluorine chlorine ether bacterium azoles and pyraclostrobin, the weight part ratio of fluorine chlorine ether bacterium azoles and pyraclostrobin is 9:1~1:
9。
2. the bactericidal composition of containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 1, it is characterised in that:
The weight part ratio of the fluorine chlorine ether bacterium azoles and pyraclostrobin is 3:1~1:3.
3. the bactericidal composition of containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 1, it is characterised in that:
The weight part ratio of the fluorine chlorine ether bacterium azoles and pyraclostrobin is 3:1~1:1.
4. the bactericidal composition of described in any item containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 1~3, feature
It is:
Weight percent of the weight summation of the fluorine chlorine ether bacterium azoles and pyraclostrobin in bactericidal composition be 20%~
50%.
5. the bactericidal composition of described in any item containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 1~3, feature
It is: any one agent allowed on pesticide is made using fluorine chlorine ether bacterium azoles and pyraclostrobin as principle active component and auxiliary agent
Type.
6. the bactericidal composition of containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 5, it is characterised in that:
The dosage form is missible oil, wettable powder, suspending agent, aqueous emulsion, microemulsion or water dispersion granule.
7. the bactericidal composition of containing chlorine fluorine ether bacterium azoles and pyraclostrobin according to claim 5, it is characterised in that:
The auxiliary agent includes emulsifier, wetting agent, stabilizer, dispersing agent, thickener, defoaming agent, antifreezing agent, filler, fills out
The mixing of one or more of material and medium.
8. the bactericidal composition of the described in any item containing chlorine fluorine ether bacterium azoles of claim 1~7 and pyraclostrobin is prevented and treated in preparation
Application on sigatoka drug.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109874799A (en) * | 2019-03-26 | 2019-06-14 | 石家庄市深泰化工有限公司 | A kind of pyraclostrobin-containing and fluorine chlorine ether bacterium azoles composite bactericide |
| CN109964944A (en) * | 2019-04-18 | 2019-07-05 | 陕西康禾立丰生物科技药业有限公司 | A kind of bactericidal composition of containing chlorine fluorine ether bacterium azoles and methoxy acrylic |
| CN115812729A (en) * | 2021-12-30 | 2023-03-21 | 石家庄市深泰化工有限公司 | Pyraclostrobin-chlorofluoromethane bactericidal composition and microemulsion and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105050406A (en) * | 2012-12-20 | 2015-11-11 | 巴斯夫农业公司 | Compositions comprising a triazole compound |
| CN109548791A (en) * | 2017-09-27 | 2019-04-02 | 燕化永乐（乐亭）生物科技有限公司 | A kind of bactericidal composition |
-
2018
- 2018-12-13 CN CN201811524124.4A patent/CN109362759A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105050406A (en) * | 2012-12-20 | 2015-11-11 | 巴斯夫农业公司 | Compositions comprising a triazole compound |
| CN109548791A (en) * | 2017-09-27 | 2019-04-02 | 燕化永乐（乐亭）生物科技有限公司 | A kind of bactericidal composition |
Non-Patent Citations (1)
| Title |
|---|
| GEORGE N.AGRIOS，沈崇尧主译: "《植物病理学》", 31 March 2009 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109874799A (en) * | 2019-03-26 | 2019-06-14 | 石家庄市深泰化工有限公司 | A kind of pyraclostrobin-containing and fluorine chlorine ether bacterium azoles composite bactericide |
| CN109874799B (en) * | 2019-03-26 | 2024-09-27 | 石家庄市深泰化工有限公司 | Pyraclostrobin and chlorine-containing compound Fluor-kresoxim-methyl compound bactericide |
| CN109964944A (en) * | 2019-04-18 | 2019-07-05 | 陕西康禾立丰生物科技药业有限公司 | A kind of bactericidal composition of containing chlorine fluorine ether bacterium azoles and methoxy acrylic |
| CN115812729A (en) * | 2021-12-30 | 2023-03-21 | 石家庄市深泰化工有限公司 | Pyraclostrobin-chlorofluoromethane bactericidal composition and microemulsion and application thereof |
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