CN109350680A

CN109350680A - It is a kind of to help pregnant pharmaceutical composition and preparation method thereof, preparation and application

Info

Publication number: CN109350680A
Application number: CN201811322783.XA
Authority: CN
Inventors: 王敏; 王舒怡
Original assignee: Chuxiong Qi Su Tang Chinese Medicine Clinic
Current assignee: Chuxiong Qi Su Tang Chinese Medicine Clinic
Priority date: 2018-11-08
Filing date: 2018-11-08
Publication date: 2019-02-19

Abstract

Pregnant pharmaceutical composition and preparation method thereof, preparation and application are helped the invention discloses a kind of.It is described that pregnant pharmaceutical composition is helped to include 10~20 parts of 40~50 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 25~35 parts of Radix Paeoniae Alba, 20~30 parts of Radix Angelicae Sinensis, 15~25 parts of Rhizoma Chuanxiong, 20~30 parts of Radix Codonopsis, 20~30 parts of Rhizoma Atractylodis Macrocephalae, 35~45 parts of Poria cocos, 10~20 parts of radix glycyrrhizae preparata, fry 20~30 parts of teasel root, fry 20~30 parts of psoralea corylifolia, 10~20 parts of raw tarragon, 20~30 parts of rhizoma cyperi processed, 20~30 parts of Radix Astragali and 5~15 parts of stir-baked CORTEX EUCOMMIAE.Preparation is pharmaceutically acceptable auxiliary material preparation is added in described helping tablet, powder, capsule, granule and pill in pregnant pharmaceutical composition.Pregnant pharmaceutical composition is helped to prepare the application in fertility drug object using for described.The all medicine joints of the present invention, synergistic effect reach and help pregnant effect.

Description

It is a kind of to help pregnant pharmaceutical composition and preparation method thereof, preparation and application

Technical field

The invention belongs to pharmaceutical technology fields, and in particular to a kind of to help pregnant pharmaceutical composition and preparation method thereof, preparation With application.

Background technique

In recent years, with the quickening of social development rhythm, the stress of people constantly increases, and diet work and rest in addition is not advised Rule, increasing environmental pollution, so that body is chronically at a kind of sub-health state, cause primary, secondary infertility patient by Year increases, and here it is the social backgrounds that pregnant sub- powder is researched and developed in doctor shop.Help pregnant product that can not be unable to satisfy people currently on the market Real demand, developing a kind of product that can solve the above problem is very important.

Summary of the invention

The first object of the present invention, which is to provide, a kind of helps pregnant pharmaceutical composition；Second is designed to provide described help The preparation method of pregnant pharmaceutical composition；Third is designed to provide the preparation for helping pregnant pharmaceutical composition；4th mesh Be the application for helping pregnant pharmaceutical composition is provided.

The first object of the present invention is achieved in that the pregnant pharmaceutical composition that helps includes the ripe of parts by weight of raw materials 40~50 parts of ground, 10~20 parts of Radix Rehmanniae, 25~35 parts of Radix Paeoniae Alba, 20~30 parts of Radix Angelicae Sinensis, 15~25 parts of Rhizoma Chuanxiong, 20~30 parts of Radix Codonopsis, 20~30 parts of Rhizoma Atractylodis Macrocephalae, 10~20 parts of radix glycyrrhizae preparata, fries 20~30 parts of teasel root, fries 20~30 parts of psoralea corylifolia, is raw 35~45 parts of Poria cocos 10~20 parts of folium artemisiae argyi, 20~30 parts of rhizoma cyperi processed, 20~30 parts of Radix Astragali and 5~15 parts of stir-baked CORTEX EUCOMMIAE.

The second object of the present invention, which is achieved in that, pulverizes and sieves each bulk pharmaceutical chemicals, is uniformly mixed by formulation ratio It obtains object and helps pregnant pharmaceutical composition.

It is pharmaceutically acceptable that the third object of the present invention is achieved in that described helping in pregnant pharmaceutical composition is added Auxiliary material preparation tablet, powder, capsule, granule and pill.

The fourth object of the present invention, which is achieved in that, described helps pregnant pharmaceutical composition in preparing fertility drug object Using.

It is of the present invention to help Siwu Tang blood-nourishing in pregnant pharmaceutical composition object space, Sijunzi Tang tonifying Qi, the positive liver of stir-baked CORTEX EUCOMMIAE temperature Kidney, tonifying Chong and Ren channels, tonifying kidney and benefiting sperm, assistant is with raw tarragon temperature governor vessel, and radix bupleuri, rhizoma cyperi tune liver stink smell processed, both temperature supports congenital kidney qi for full side With production of sperm, and the product trained and mend the temper day after tomorrow to change blood, and help to adjust liver tonifying Qi, keep menses sufficient, punching is appointed feeding, and tire is pregnant to be into.

Specific embodiment

Below with reference to embodiment, the present invention is further illustrated, but the present invention is limited in any way, Based on present invention teach that it is made it is any transform or replace, all belong to the scope of protection of the present invention.

It is of the present invention that help pregnant pharmaceutical composition include 40~50 parts of radix rehmanniae preparata, the Radix Rehmanniae 10~20 of parts by weight of raw materials Part, 25~35 parts of Radix Paeoniae Alba, 20~30 parts of Radix Angelicae Sinensis, 15~25 parts of Rhizoma Chuanxiong, 20~30 parts of Radix Codonopsis, 20~30 parts of Rhizoma Atractylodis Macrocephalae, Poria cocos 35~ 45 parts, 10~20 parts of radix glycyrrhizae preparata, 20~30 parts of teasel root of stir-fry, stir-fry 20~30 parts of psoralea corylifolia, 10~20 parts of raw tarragon, rhizoma cyperi processed 10 ~30 parts, 20~30 parts of Radix Astragali and 5~15 parts of stir-baked CORTEX EUCOMMIAE.

The pregnant pharmaceutical composition that helps includes 10~15 parts of 40~45 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, Radix Paeoniae Alba 25~30 parts, 20~25 parts of Radix Angelicae Sinensis, 15~20 parts of Rhizoma Chuanxiong, 20~25 parts of Radix Codonopsis, 20~25 parts of Rhizoma Atractylodis Macrocephalae, 35~40 parts of Poria cocos, toast 10~15 parts of Radix Glycyrrhizae fries 20~25 parts of teasel root, fries 20~25 parts of psoralea corylifolia, 10~15 parts of raw tarragon, 20~25 parts of rhizoma cyperi processed, Huang 20~25 parts and 5~10 parts of stir-baked CORTEX EUCOMMIAE of stilbene.

The pregnant pharmaceutical composition that helps includes 15~20 parts of 45~50 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, Radix Paeoniae Alba 30~35 parts, 25~30 parts of Radix Angelicae Sinensis, 20~25 parts of Rhizoma Chuanxiong, 25~30 parts of Radix Codonopsis, 25~30 parts of Rhizoma Atractylodis Macrocephalae, 40~45 parts of Poria cocos, toast 15~20 parts of Radix Glycyrrhizae fries 25~30 parts of teasel root, fries 25~30 parts of psoralea corylifolia, 15~20 parts of raw tarragon, 25~30 parts of rhizoma cyperi processed, Huang 25~30 parts and 10~15 parts of stir-baked CORTEX EUCOMMIAE of stilbene.

It is described help pregnant pharmaceutical composition include 20 parts of 40 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 25 parts of Radix Paeoniae Alba, when Return 20 parts, 17 parts of Rhizoma Chuanxiong, 22 parts of Radix Codonopsis, 22 parts of Rhizoma Atractylodis Macrocephalae, 37 parts of Poria cocos, 22 parts of radix glycyrrhizae preparata, fries 22 parts of teasel root, fries psoralea corylifolia 22 Part, 12 parts of raw tarragon, 22 parts of rhizoma cyperi processed, 22 parts of Radix Astragali and 7 parts of stir-baked CORTEX EUCOMMIAE.

It is described help pregnant pharmaceutical composition include 17 parts of 47 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 32 parts of Radix Paeoniae Alba, when Return 27 parts, 22 parts of Rhizoma Chuanxiong, 27 parts of Radix Codonopsis, 27 parts of Rhizoma Atractylodis Macrocephalae, 42 parts of Poria cocos, 17 parts of radix glycyrrhizae preparata, fries 22 parts of teasel root, fries psoralea corylifolia 22 Part, 17 parts of raw tarragon, 22 parts of rhizoma cyperi processed, 22 parts of Radix Astragali and 12 parts of stir-baked CORTEX EUCOMMIAE.

It is described help pregnant pharmaceutical composition include 15 parts of 45 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 30 parts of Radix Paeoniae Alba, when Return 25 parts, 20 parts of Rhizoma Chuanxiong, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Atractylodis Macrocephalae, 40 parts of Poria cocos, 15 parts of radix glycyrrhizae preparata, fries 25 parts of teasel root, fries psoralea corylifolia 25 Part, 15 parts of raw tarragon, 25 parts of rhizoma cyperi processed, 25 parts of Radix Astragali and 10 parts of stir-baked CORTEX EUCOMMIAE.

The preparation method of the present invention for helping pregnant pharmaceutical composition is that each bulk pharmaceutical chemicals pulverize and sieve, matches by formula It obtains object than being uniformly mixed and helps pregnant pharmaceutical composition.

Described pulverizing and sieving is to crush to sieve with 100 mesh sieve.

The preparation of the present invention for helping pregnant pharmaceutical composition is that pharmacy is added in described helping in pregnant pharmaceutical composition Tablet, powder, capsule, granule and the pill of upper acceptable auxiliary material preparation.

The application of the present invention for helping pregnant pharmaceutical composition is that described to help pregnant pharmaceutical composition to help in preparation pregnant Application in drug.

Case is embodied, the present invention will be further described below:

Embodiment 1

Take raw material radix rehmanniae preparata 40g, Radix Rehmanniae 10g, Radix Paeoniae Alba 25g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 15g, Radix Codonopsis 20g, Rhizoma Atractylodis Macrocephalae 20g, Poria cocos 35g, radix glycyrrhizae preparata 10g, it fries teasel root 20g, fry psoralea corylifolia 20g, raw tarragon 10g, rhizoma cyperi 20g processed, Radix Astragali 20g and stir-baked CORTEX EUCOMMIAE 5g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 2

Take raw material radix rehmanniae preparata 50g, Radix Rehmanniae 20g, Radix Paeoniae Alba 35g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 25g, Radix Codonopsis 30g, Rhizoma Atractylodis Macrocephalae 30g, Poria cocos 45g, radix glycyrrhizae preparata 20g, it fries teasel root 30g, fry psoralea corylifolia 30g, raw tarragon 20g, rhizoma cyperi 30g processed, Radix Astragali 30g and stir-baked CORTEX EUCOMMIAE 15g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 3

Take raw material radix rehmanniae preparata 45g, Radix Rehmanniae 15g, Radix Paeoniae Alba 30g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong 20g, Radix Codonopsis 25g, Rhizoma Atractylodis Macrocephalae 25g, Poria cocos 40g, radix glycyrrhizae preparata 15g, it fries teasel root 25g, fry psoralea corylifolia 25g, raw tarragon 15g, rhizoma cyperi 25g processed, Radix Astragali 25g and stir-baked CORTEX EUCOMMIAE 10g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 4

Take raw material radix rehmanniae preparata 42g, Radix Rehmanniae 12g, Radix Paeoniae Alba 22g, Radix Angelicae Sinensis 22g, Rhizoma Chuanxiong 17g, Radix Codonopsis 22g, Rhizoma Atractylodis Macrocephalae 22g, Poria cocos 37g, radix glycyrrhizae preparata 12g, it fries teasel root 22g, fry psoralea corylifolia 22g, raw tarragon 12g, rhizoma cyperi 22g processed, Radix Astragali 22g and stir-baked CORTEX EUCOMMIAE 7g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 5

Take raw material radix rehmanniae preparata 47g, Radix Rehmanniae 17g, Radix Paeoniae Alba 32g, Radix Angelicae Sinensis 22g, Rhizoma Chuanxiong 22g, Radix Codonopsis 22g, Rhizoma Atractylodis Macrocephalae 22g, Poria cocos 42g, radix glycyrrhizae preparata 17g, it fries teasel root 27g, fry psoralea corylifolia 27g, raw tarragon 17g, rhizoma cyperi 22g processed, Radix Astragali 22g and stir-baked CORTEX EUCOMMIAE 12g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 6

Take raw material radix rehmanniae preparata 40g, Radix Rehmanniae 20g, Radix Paeoniae Alba 35g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 10g, Radix Codonopsis 20g, Rhizoma Atractylodis Macrocephalae 20g, Poria cocos 45g, radix glycyrrhizae preparata 20g, it fries teasel root 20g, fry psoralea corylifolia 25g, raw tarragon 15g, rhizoma cyperi 25g processed, Radix Astragali 22g and stir-baked CORTEX EUCOMMIAE 10g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 7

Take raw material radix rehmanniae preparata 50g, Radix Rehmanniae 20g, Radix Paeoniae Alba 30g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong 25g, Radix Codonopsis 20g, Rhizoma Atractylodis Macrocephalae 30g, Poria cocos 40g, radix glycyrrhizae preparata 15g, it fries teasel root 30g, fry psoralea corylifolia 30g, raw tarragon 20g, rhizoma cyperi 20g processed, Radix Astragali 29g and stir-baked CORTEX EUCOMMIAE 9g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 8

Take raw material radix rehmanniae preparata 46g, Radix Rehmanniae 16g, Radix Paeoniae Alba 31g, Radix Angelicae Sinensis 29g, Rhizoma Chuanxiong 23g, Radix Codonopsis 26g, Rhizoma Atractylodis Macrocephalae 30g, Poria cocos 43g, radix glycyrrhizae preparata 16g, it fries teasel root 28g, fry psoralea corylifolia 29g, raw tarragon 16g, rhizoma cyperi 27g processed, Radix Astragali 27g and stir-baked CORTEX EUCOMMIAE 10g, point It Fen Sui not sieve with 100 mesh sieve, be uniformly mixed and obtain object and help pregnant pharmaceutical composition.

Embodiment 9

It is in blocks that pharmaceutically acceptable auxiliary material preparation is added with the helping in pregnant pharmaceutical composition of being prepared of embodiment 2 Agent.

Embodiment 10

Pharmaceutically acceptable auxiliary material is added with the helping in pregnant pharmaceutical composition of being prepared of embodiment 3 and is prepared into capsule Agent.

Embodiment 11

Pharmaceutically acceptable auxiliary material is added with the helping in pregnant pharmaceutical composition of being prepared of embodiment 4 and is prepared into particle Agent.

Embodiment 12

Pharmaceutically acceptable auxiliary material preparation pelletization is added with the helping in pregnant pharmaceutical composition of being prepared of embodiment 6 Agent.

Embodiment 13

Clinical test, total effective rate are carried out with the pharmaceutical composition that 1~embodiment of embodiment 8 is prepared respectively 97.8%.It is described further below with part real case:

Case one

On December 6th, 2016: Pan so-and-so, female, 32 years old, it is existing one son, successively miscarry 2 times, be intended to have two babies, at the beginning of 2017 in Chuxiong City Hospitals inspection: fibroid 3.4*2.3CM, doctor suggest leading fibroid decollement, and otherwise pregnancy is difficult Or myomata further increases after pregnancy, but patient still adheres to first being pregnant and considers further that operation afterwards, looks for Wang Min medical treatment to this shop then. Patient's primary symptom be gastral cavilty turgor, diet reduce, when have nauseous nausea, menstrual period postpone, and tongue nature is light red, whitish tongue, deep thready pulse.It is dialectical to be Born of the same parents are hindered for the insufficiency of the spleen with overabundance of dampness, phlegm wet, control the method for giving invigorating spleen to remove dampness, menstruation regulating eliminating phlegm, the quasi- invigorating spleen to remove dampness soup in side adds and subtracts 6 doses, embodiment 3 The pharmaceutical composition 2 being prepared is wrapped.

On December 28th, 2016, further consultation, gastral cavilty turgor discomfort are clearly better, and diet is promoted, last menstrual period December 14, Patient's taste improve, eumenorrhea, and quasi- 3 doses of Tiaojing Cuyun side of side, the pharmaceutical composition 3 that embodiment 3 is prepared is wrapped, and amount to 6 Agent.

On 2 6th, 2017, patient went to doctor shop to inform early pregnancy 5w+, and phone tracking later understands, pregnant woman's term birth.

Case two

On January 13rd, 2017, Mr. Li, female 32 years old, get married 4 years, post-abortion is intended to pregnant for several times.Patient's primary symptom is menstrual flow Less, color is black, last menstrual period December 24, and with tinnitus, leukorrhea amount is more, the cold then diarrhea of food acid, when have dizzy pain.Doctor trained in Western medicine inspection has yin Road inflammation, cervical erosion, pelvic inflammatory disease etc. were once miscarried three times, for the first time voluntarily miscarriage, after twice equal tire stop educating, last miscarriage 2016 In June in year, tongue nature is light red, and whitish tongue is slightly dry.Dialectical is the dysfunction of the spleen in transport, and the quasi- invigorating the spleen dehumidifying rising Yang stop-band soup in side adds and subtracts 6 doses, embodiment 8 The pharmaceutical composition 2 being prepared is wrapped.

On 2 3rd, 2017, further consultation, the symptoms such as patient's diarrhea, dizzy pain, leukorrhea be more were clearly better, last menstrual period January 27, the red amount of color was moderate, passed through 5 completely, tongue nature is light red, and tongue fur is thin white, deep thready pulse.Side quasi- 6 doses of Tiaojing Cuyun side, embodiment 8 The pharmaceutical composition 4 being prepared is wrapped.

On May 3rd, 2017, for patient because gestation headache comes to go to a doctor, patient tells doctor Mr. Yu state on April 27 grade front three doctor Institute checks prompt Urine HCG positive (pregnancy), and tongue nature is light red, and whitish tongue, slippery is slightly tight, and the quasi- DANGGUI SHAOYAO SAN in side closes Guizhi decoction plus-minus 3 doses, the pharmaceutical composition 3 that embodiment 8 is prepared is wrapped.

Case three

On July 18th, 2016, Sun, female 35 years old, recombinate family after divorce, once primary with former husband's pregnancy in 2012, because Ectopic pregnancy salpingectomy on the right side of bottom row in 2012.Ectopic pregnancy again is feared after patient is remarried, is introduced and is gone to through friend Doctor seeks medical advice in shop.Last menstrual period on July 10th, 2016, color secretly measure it is moderate, pass through 4 days it is clean, the menstrual period soreness of waist is out of strength, receive dormancy can, two Just it adjusts, tongue nature is light red, and whitish tongue is greasy, and arteries and veins is thin and delicate.Dialectical is kidney deficiency and liver, controls and gives 6 doses of Gui-shen pill plus-minus, embodiment 2 is prepared Pharmaceutical composition 2 wrap.

On August 15th, 2016, further consultation, patient reflect the menstrual cycle, color, through measure it is normal, it is desirable that regulating menstruation and assisting pregnancy, side The pharmaceutical composition 3 that quasi- 3 doses of regulating menstruation and assisting pregnancy side's plus-minus, embodiment 2 are prepared is wrapped.The each clean period of doctor's advice comes after 2 days Shop further consultation is cured, after so following the doctor's advice treatment 2 months, patient comes to cure shop informing and has been pregnant, and thanks to show.

Case four

On 2 27th, 2016, Zhang, female, 28 years old, get married 4 years, long-term standby pregnant and it is infertile, through friend introduce come to cure shop It seeks medical advice.Readme: doctor trained in Western medicine checks that indices are without exception, and last menstrual period 8 days 2 months, menstrual period were normal, but black through color, accompany Clot, bellyache in menstrual period is obvious, and with the soreness of waist, tongue nature is light red ecchymosis, and tongue fur is thin white, forceless deep pulse, and chi pulse is more so.Dialectical is cold blood coagulation The stasis of blood, deficiency of kidney-QI are controlled and give pan-fried 4 doses of the plus-minus of the logical stasis of blood, and the positive menstruation-regulating soup of kidney tonifying temperature adds and subtracts 4 doses, the pharmaceutical composition that embodiment 6 is prepared Object 2 wraps.

On March 15th, 2016, further consultation, patient take a favorable turn through color, amount, and clot is reduced, and menstrual period still feel abdominal pain, the soreness of waist. Dialectical to improve for palace cold, qi and blood gradually fills, and original side slightly does plus-minus and respectively takes 3 doses again.Continue further consultation after advising patient to take medicine, after be changed to adjust It is treated through progestogenic, gives then and help 6 doses of pregnant menstruation regulating side, the pharmaceutical composition 6 that embodiment 6 is prepared is wrapped, and Following Prescription is advised to advise on time It takes.

On July 24th, 2016, the patient husband wife's side that tells by telephone have been pregnant 5w+.

Case five

On April 27th, 2016, text so-and-so, female 34 years old, is intended to have two babies, and fails to be pregnant within standby pregnant 1 year.Once 1 was miscarried before 2 years It is secondary, last menstrual period April 5, pass through 6 days it is clean, the black amount of color is moderate, underbelly pain of passing through, the soreness of waist, premenstrual breast pain, constipation, 16 the People's Hospital Zhou April in 2016 checks: Pelvic varicosis, a small amount of hydrops of pelvic cavity, uterine neck Na Shi bubble, inner membrance 0.6cm, Red tongue body has a petechia, whitish tongue, and deeptensepulse is puckery.It is diagnosed as cold solidifying uterus, conception vessel stasis blocking, controls and gives wenjing decoction conjunction Huoluo Xiaoling Dan plus-minus 4 Agent, timely further consultation after the packet of pharmaceutical composition 2 that embodiment 7 is prepared advises patient to take medicine.

On May 4th, 2016, further consultation, patient's self-induction underbelly secret anguish, lunar are intended to come, no soreness of waist swollen breasts, and tongue nature is light Red, whitish tongue, deep thready pulse gives the carefree bazhen decoction of patient and adds and subtracts 2 doses, and cooperation acupuncture warms up the mode of ancient Chinese music through treating.Next day color in the period, blood Amount is normal.Patient's palace cold improves after treatment, and conception vessel is unobstructed, gives 6 doses of regulating menstruation and assisting pregnancy side, the medicine group that embodiment 7 is prepared then It closes object 4 to wrap, follows the doctor's advice and take on schedule.

On October 13rd, 2017, patient and family members, which take its girl baby and come to cure shop, to report success and expresses thanks.

Case six

On July 17th, 2016, Ma, female, 28 years old, menarche 15 years old, on June 6th, 2011 got married.Seek west after marriage It cures and treats, unpregnancy so far is introduced through friend and doctor shop is gone to seek medical advice, and patient tells the premenstrual soreness of waist, cold and pain in the lower abdomen falling inflation, swollen breasts, Dysphoria.Last menstrual period July 10, pass through 5 days it is clean, the light amount of color is few.Doctor trained in Western medicine checks uterus size, form, bilateral attachment Without exception, ovulation tests have no graaffian follicle.Pale tongue with white fur, while there is indentation, deep thready pulse and string, right side chi pulse are weak.Dialectical is liver The strongly fragrant stagnation of the circulation of vital energy, deficiency of kidney-QI are controlled and give positive 3 doses of menstruation-regulating soup plus-minus of 3 doses of Xiaoyao San plus-minus, kidney tonifying temperature.

On August 8th, 2016, further consultation, menstrual period have closed on, and do not occur the soreness of waist, cold and pain in the lower abdomen, swollen breasts, and tongue nature is light red, tongue fur Bao Bai, deep thready pulse, dialectical kidney qi are gradually filled, and qi and blood is multiple normal, are controlled and are given 3 doses of regulating menstruation and assisting pregnancy side, the pharmaceutical composition that embodiment 1 is prepared Object 3 wraps.It advises patient to take medicine on schedule, treats March by this.

On November 18th, 2016 comes to cure within nearly 20 days shop because of menstruation postponement and go to a doctor, look into Urine HCG positive.

Case seven

On January 29th, 2016, Sun, female 40 years old, get married 17 years, once Gr1 P0 AB1 before the several years, so far s.m.p, the last moon Through January 21,3 days are passed through completely, the black amount of color is moderate, and underbelly pain of passing through, the soreness of waist, the state of mind is poor, and poor dreaminess of sleeping is not intended to drink Food, tongue nature is light fat, whitish tongue, deeptensepulse.It is diagnosed as speen-kidney dificiency, controls and gives 4 doses of plus-minus of Gui-shen pill conjunction guipi decoction, Appetizing spleen-tonifying powder 2 wraps, Timely further consultation after the packet of pharmaceutical composition 2 that embodiment 5 is prepared advises patient to take medicine.

On 2 23rd, 2016, further consultation, patient's self-induction state of mind improved, and last menstrual period 22 days 2 months, no soreness of waist, tongue nature was light Red, whitish tongue, deep thready pulse gives the carefree bazhen decoction of patient and adds and subtracts 2 doses, and cooperation acupuncture warms up the mode of ancient Chinese music through treating.Next day color in the period, blood Amount is normal.The weakness of the spleen and the stomach improvement of patient after treatment, kidney qi is sufficient, gives 5 doses of regulating menstruation and assisting pregnancy side, the medicine that embodiment 5 is prepared then Compositions 4 wrap.

On March 10th, 2017, patient tell by telephone and gave birth to a boy baby, mother and sons' health before January.

Case eight

On July 17th, 2016, Ma, female 28 years old, are not pregnant after Therapeutic Abortion, delayed menstrual cycle for 2 years again, and 35~40 days one Row, last menstrual period July 11, pass through 5 days it is clean, the dark red amount of color is moderate, accompanies clot, and with the soreness of waist, cold and pain in the lower abdomen is made swollen.Tongue nature It is dark red, tongue fur is thin white, deep thready pulse.Dialectical: deficiency of kidney yang, fertility, the positive menstruation-regulating soup of square quasi-complement kidney temperature add and subtract 6 doses.

On August 23rd, 2016, further consultation last menstrual period August 9th, pass through 4 completely, and the red amount of color is moderate, and clot is reduced, nothing The soreness of waist.Patient's self-induction physical condition restores good, ask whether can standby pregnant, patients blood filled, and has had pregnancy condition, side Quasi- 6 doses of regulating menstruation and assisting pregnancy side, the pharmaceutical composition 3 that embodiment 4 is prepared are wrapped.

On December 4th, 2016, patient is because progesterone deficiency goes to doctor shop medical, and early pregnancy 7w+, tongue nature is light red, whitish tongue, deeptensepulse Sliding, dialectical is kidney deficiency insufficiency of vital energy and blood, quasi- 4 doses of the Chong Ren Meridians Debility in side prevent miscarriage help it is pregnant.

Claims

1. a kind of help pregnant pharmaceutical composition, it is characterised in that the pregnant pharmaceutical composition that helps includes the ripe of parts by weight of raw materials 40~50 parts of ground, 10~20 parts of Radix Rehmanniae, 25~35 parts of Radix Paeoniae Alba, 20~30 parts of Radix Angelicae Sinensis, 15~25 parts of Rhizoma Chuanxiong, 20~30 parts of Radix Codonopsis, 20~30 parts of Rhizoma Atractylodis Macrocephalae, 10~20 parts of radix glycyrrhizae preparata, fries 20~30 parts of teasel root, fries 20~30 parts of psoralea corylifolia, raw Chinese mugwort 35~45 parts of Poria cocos 10~20 parts of leaf, 20~30 parts of rhizoma cyperi processed, 20~30 parts of Radix Astragali and 5~15 parts of stir-baked CORTEX EUCOMMIAE.

2. according to claim 1 help pregnant pharmaceutical composition, it is characterised in that described helps pregnant pharmaceutical composition packet Include 10~15 parts of 40~45 parts of radix rehmanniae preparata, Radix Rehmanniae, 25~30 parts of Radix Paeoniae Alba, 20~25 parts of the Radix Angelicae Sinensis, Rhizoma Chuanxiong 15~20 of parts by weight of raw materials Part, 20~25 parts of Radix Codonopsis, 20~25 parts of Rhizoma Atractylodis Macrocephalae, 35~40 parts of Poria cocos, 10~15 parts of radix glycyrrhizae preparata fry 20~25 parts of teasel root, fry and mend 20~25 parts of bone fat, 10~15 parts of raw tarragon, 20~25 parts of rhizoma cyperi processed, 20~25 parts of Radix Astragali and 5~10 parts of stir-baked CORTEX EUCOMMIAE.

3. according to claim 1 help pregnant pharmaceutical composition, it is characterised in that described helps pregnant pharmaceutical composition packet Include 15~20 parts of 45~50 parts of radix rehmanniae preparata, Radix Rehmanniae, 30~45 parts of Radix Paeoniae Alba, 25~30 parts of the Radix Angelicae Sinensis, Rhizoma Chuanxiong 20~25 of parts by weight of raw materials Part, 25~30 parts of Radix Codonopsis, 25~30 parts of Rhizoma Atractylodis Macrocephalae, 40~45 parts of Poria cocos, 15~20 parts of radix glycyrrhizae preparata fry 25~30 parts of teasel root, fry and mend 25~30 parts of bone fat, 15~20 parts of raw tarragon, 25~30 parts of rhizoma cyperi processed, 25~30 parts of Radix Astragali and 10~15 parts of stir-baked CORTEX EUCOMMIAE.

4. according to claim 1 help pregnant pharmaceutical composition, it is characterised in that described helps pregnant pharmaceutical composition packet Include 10 parts of 45 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 30 parts of Radix Paeoniae Alba, 25 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 23 parts of Radix Codonopsis, 23 parts of Rhizoma Atractylodis Macrocephalae, 35 parts of Poria cocos, 13 parts of radix glycyrrhizae preparata, fry 23 parts of teasel root, fry 23 parts of psoralea corylifolia, 12 parts of raw tarragon, 23 parts of rhizoma cyperi processed, 23 parts of Radix Astragali and 8 parts of stir-baked CORTEX EUCOMMIAE.

5. according to claim 1 help pregnant pharmaceutical composition, it is characterised in that described helps pregnant pharmaceutical composition packet Include 17 parts of 45 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 30 parts of Radix Paeoniae Alba, 25 parts of Radix Angelicae Sinensis, 23 parts of Rhizoma Chuanxiong, 27 parts of Radix Codonopsis, 27 parts of Rhizoma Atractylodis Macrocephalae, 42 parts of Poria cocos, 17 parts of radix glycyrrhizae preparata, fry 23 parts of teasel root, fry 23 parts of psoralea corylifolia, 17 parts of raw tarragon, 23 parts of rhizoma cyperi processed, 23 parts of Radix Astragali and 12 parts of stir-baked CORTEX EUCOMMIAE.

6. according to claim 1 help pregnant pharmaceutical composition, it is characterised in that described helps pregnant pharmaceutical composition packet Include 15 parts of 45 parts of radix rehmanniae preparata, the Radix Rehmanniae of parts by weight of raw materials, 30 parts of Radix Paeoniae Alba, 25 parts of Radix Angelicae Sinensis, 20 parts of Rhizoma Chuanxiong, 25 parts of Radix Codonopsis, 25 parts of Rhizoma Atractylodis Macrocephalae, 40 parts of Poria cocos, 15 parts of radix glycyrrhizae preparata, fry 25 parts of teasel root, fry 25 parts of psoralea corylifolia, 15 parts of raw tarragon, 25 parts of rhizoma cyperi processed, 25 parts of Radix Astragali and 10 parts of stir-baked CORTEX EUCOMMIAE.

7. a kind of any preparation method for helping pregnant pharmaceutical composition of claim 1~6, it is characterised in that be Jiang Geyuan Material medicine pulverizes and sieves, and is uniformly mixed by formulation ratio and obtains object and help pregnant pharmaceutical composition.

8. the preparation method according to claim 7 for helping pregnant pharmaceutical composition, it is characterised in that described pulverizes and sieves It is to crush to sieve with 100 mesh sieve.

9. a kind of any preparation for helping pregnant pharmaceutical composition of claim 1~6, it is characterised in that described helping is pregnant Tablet, powder, capsule, granule and the pill of pharmaceutically acceptable auxiliary material preparation are added in pharmaceutical composition.

10. a kind of any application for helping pregnant pharmaceutical composition of claim 1~6, it is characterised in that described helping is pregnant Pharmaceutical composition preparing the application in fertility drug object.