CN109350292B - Mouse lateral position vertebra fixed bolster - Google Patents
Mouse lateral position vertebra fixed bolster Download PDFInfo
- Publication number
- CN109350292B CN109350292B CN201811173685.4A CN201811173685A CN109350292B CN 109350292 B CN109350292 B CN 109350292B CN 201811173685 A CN201811173685 A CN 201811173685A CN 109350292 B CN109350292 B CN 109350292B
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- fixing
- screw
- fixing device
- clamping
- rod
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- 238000005452 bending Methods 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 15
- 241000699666 Mus <mouse, genus> Species 0.000 description 16
- 241001465754 Metazoa Species 0.000 description 6
- 230000000007 visual effect Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 210000003594 spinal ganglia Anatomy 0.000 description 5
- 238000010862 gear shaping Methods 0.000 description 4
- 208000003098 Ganglion Cysts Diseases 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 208000005400 Synovial Cyst Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000000278 spinal cord Anatomy 0.000 description 3
- 210000003050 axon Anatomy 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 241000700605 Viruses Species 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000013528 artificial neural network Methods 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgical Instruments (AREA)
Abstract
The invention provides a fixed support for lateral position vertebra of a mouse, which comprises a fixed support main body consisting of a spine clamp holder, fixed legs and a fixing device, wherein the lower part of the spine clamp holder is arranged at one end of a clamping rod through a screw, and the other end of the clamping rod is connected with a jack on the fixing device; a rotating shaft is arranged on one side of the fixed foot, and a fixed screw is arranged above the rotating shaft; screw holes are formed in the side parts of the fixing device, and rotating shaft holes are formed below the screw holes; the spine clamp holder consists of a stud, a clamping piece, a triangular prism groove, a spring and an axle center fixing rod. The spine clamp holder, the fixing legs and the fixing device are arranged, so that different lateral lying angles can be conveniently adjusted during lateral lying position operation of a mouse, the operation effect is improved, the structure is simple and reasonable, the fixing effect is good, the use is convenient, and the cost is low.
Description
Technical Field
The invention relates to a lateral position vertebra fixing bracket for a mouse.
Background
With the development of optogenetic and chemical genetic technologies in recent years, a more thorough understanding of the structure and function of the neural network of the brain is provided. However, based on the anatomical structure characteristics of spinal cord and the research of dorsal root ganglion, the research of the horizontal nerve loop of spinal cord and dorsal root ganglion of the whole animal is limited at present, because the dorsal root ganglion is under the osseous surrounding in the transverse process hole, and has tiny volume, and the difficulty of precisely injecting virus into the dorsal root ganglion is high, so the precise injection operation of the dorsal root ganglion is still in an immature stage at present.
The Chinese patent publication number is CN 104873289B, the name of the invention is animal vertebra fixing device, which comprises a first clamp, a second clamp and a containing space; the first clamp is provided with a U-shaped groove; the front ends of the two sides of the U-shaped groove are bent to form two first gear shaping teeth; the second clamp is matched with the U-shaped groove and can slide in the U-shaped groove; the second clamp is provided with a second gear shaping matched with the first gear shaping; the accommodating space is matched with the two first gear shaping teeth and communicated with the clamping parts of the first clamp and the second clamp. By means of the device, a brake check is performed after the animal is awake, and the brake effect is found to be good, and spinal cord segments of one ganglion and one vertebral segment can be observed at the same time. Furthermore, in spinal axon studies, the dorsal spine of animals can be observed with axons. However, the existing animal vertebra fixing device has the problems that the fixing effect is poor, the use is inconvenient, the lateral lying angle of an animal during operation cannot be adjusted due to the arrangement of the structure, the accurate operation is difficult, the operation effect is reduced, the arrangement of the clamp influences the operation visual field, and the clamping of the spine is inconvenient.
Disclosure of Invention
In order to make up the defects of the prior art, the invention provides the lateral position spine fixing bracket for the mice, which has a good fixing effect, when in use, the mice can be fixed by rotating the spine clamp holder, so that a proper operation angle can be found conveniently, in addition, the middle of the clamping piece on the spine clamp holder is bent outwards and is only fixed on the upper section and the lower section of an operation stage, the visual field of the operation can be fully exposed, so that the operation effect is improved, the triangular prism groove is adopted, the fixing effect of the mice is improved, and the fixing of spines with different lengths and sizes is allowed. The fixed foot adopts integrative setting with the base, has further improved this support stability and fastness, simultaneously can angle regulation, makes it can be better accomplish the operation of lying on one's side, has effectively solved the problem that exists among the prior art.
The technical scheme adopted by the invention for solving the technical problems is as follows:
the utility model provides a mouse lateral position vertebra fixed bolster, includes the fixed bolster main part that backbone holder, fixed leg and fixing device constitute, its characterized in that: the lower part of the spine clamp holder is arranged at one end of the clamping rod through a screw, and the other end of the clamping rod is connected with a jack on the fixing device; the two fixing feet are arranged and are integrated with the base, a rotating shaft is arranged on one side of each fixing foot, and a fixing screw is arranged above the rotating shaft; screw holes are formed in the side parts of the fixing device, and rotating shaft holes are formed below the screw holes; the rotating shaft penetrates through the rotating shaft hole to connect the upper part of the fixed foot with the upper part of the fixing device, and the lower part of the fixed foot and the lower part of the fixing device are fixed through the screw hole by a fixing screw; the spine clamp holder consists of a stud, a clamping piece, a triangular prism groove, a spring and an axle center fixing rod, wherein the axle center fixing rod is arranged below the stud, and the spine clamp holder is arranged at the upper end of the clamping rod under the cooperation of the stud and the axle center fixing rod; a spring is arranged on one side face of the axle center fixing rod, a clamping piece is arranged on the spring, and a triangular prism groove is formed in the clamping piece.
The base is the flat cuboid of stainless steel material, extends there are two fixed feet on the base, and its fixed foot is located the upper right corner parallel arrangement of base, and the installation fixing device of being convenient for makes its better completion follow-up work, and simple structure is reasonable, and is fixed firm, and the selected material weight is light, convenient transportation does not take place corrosion.
The shape of fixed foot is the hexagonal prism, is equipped with on fixed foot with the screw hole on the fixing device and the corresponding jack in pivot hole, and its shorter base of fixed foot is connected the base can make fixed foot and fixing device better cooperation, and can realize the regulation of fixing device angle to be applicable to the emergence of multiple condition, and the setting of structure does not have sharp-pointed edges and corners, improves the practicality.
The fixing device is in a seven-prism shape, the triangular head faces downwards, the flat head faces upwards, the clamping rod is inserted into the jack of the flat head part of the fixing device, nuts and screws are arranged at two ends of the clamping rod, the fixing device is convenient to rotate, the angle of the fixing device is convenient to adjust, the triangular head can ensure that the rotating range under the same volume is wider, and the flat head faces upwards to prevent sharp edges and corners, so that the fixing device is convenient to operate.
The fixed screw adopts a screw rod with the diameter of 0.6mm and a large screw head with the diameter of 3 mm; the clamping piece is provided with two clamping pieces, the width and the thickness of the clamping piece are 2.5mm, the position and the diameter of the selected fixing screw are set, the screw is directly rotated by hands of a user, the rotation of a using instrument is avoided, the use is convenient, the clamping piece is humanized, the size of the clamping piece is set, the exposed visual field is small, the damage is small, and the clamping of the spine is convenient.
When the clamping piece is bent towards the positive direction of the y axis, the bending inner diameter is 5mm, the starting part of the clamping piece is bent towards the negative direction of the y axis, so that the mouse can be conveniently fixed, the mouse can be effectively prevented from being extruded in the process of the clamping piece, the operation vision is not influenced, and meanwhile, the ganglion of the operation section can be fully exposed, so that the operation is better completed.
The triangular prism grooves are respectively arranged at the far ends and the near ends of the two clamping pieces, the triangular prism grooves and the clamping pieces form an angle of 45 degrees, and two points are formed into a line when the upper section and the lower section of the operation section are clamped, so that the fixing effect is improved, the selected grooves are used for fixing transverse processes of the spine, and the setting of the angle of 45 degrees can allow the fixation of the spine with different lengths and sizes in a certain range.
The invention adopts the scheme, the structural design is reasonable, the fixing effect is better, when in use, the mouse spine can be fixed by rotating the spine clamp holder, so that a proper operation angle can be found conveniently, then the support body is better and stable by adjusting the fixing screw, and the middle of the clamping piece on the spine clamp holder is outwards bent and is only fixed on the upper section and the lower section of the operation stage, so that the visual field of the operation can be fully exposed, the operation effect is improved, the triangular prism grooves on the clamping piece are adopted, the fixing effect of the mouse is improved, and the fixing of spines with different lengths and sizes is allowed. When the operation is inconvenient, the angle of the fixing device can be adjusted through the rotating shaft, so that the lateral position of the mouse can be better convenient for the operation, and the mouse can well complete the work requirement.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic perspective view of the spinal holder of the present invention.
Fig. 3 is a schematic perspective view of the fixing device of the present invention.
In the figure: 1. the device comprises a spine clamp holder, 11, a stud, 12, clamping pieces, 13, triangular prism grooves, 14, a spring, 15, an axle center fixing rod, 2, a fixing foot, 3, a fixing device, 4, a rotating shaft, 5, a clamping rod, 6, a fixing screw, 7, a base, 8, an inserting hole, 9, a screw hole, 10 and a rotating shaft hole.
Detailed Description
In order to clearly illustrate the technical features of the present solution, the present invention will be described in detail below with reference to the following detailed description and the accompanying drawings.
As shown in fig. 1-3, the invention provides a fixing support for the lateral position of a mouse, which comprises a fixing support main body consisting of a spine clamp holder 1, fixing legs 2 and a fixing device 3, wherein the lower part of the spine clamp holder 1 is installed at one end of a clamping rod 5 through a screw, and the other end of the clamping rod 5 is connected with a jack 8 on the fixing device 3; the two fixing feet 2 are arranged and are integrated with the base 7, a rotating shaft 4 is arranged on one side of the fixing feet 2, and a fixing screw 6 is arranged above the rotating shaft 4; the side part of the fixing device 3 is provided with a screw hole 9, and a rotating shaft hole 10 is arranged below the screw hole 9; the rotating shaft 4 passes through the rotating shaft hole 10 to connect the upper part of the fixed foot 2 with the upper part of the fixing device 3, and the lower part of the fixed foot 2 and the lower part of the fixing device 3 are fixed by the fixing screw 6 through the screw hole 9; the spine clamp holder 1 consists of a stud 11, a clamping piece 12, a triangular prism groove 13, a spring 14 and an axle center fixing rod 15, wherein the axle center fixing rod 15 is arranged below the stud 11, and the spine clamp holder 1 is arranged at the upper end of the clamping rod 5 under the cooperation of the stud 11 and the axle center fixing rod 15; a spring 14 is arranged on one side surface of the axle center fixing rod 15, a clamping piece 12 is arranged on the spring 14, and a triangular prism groove is arranged on the clamping piece 12.
The base 7 is a flat cuboid made of stainless steel, two fixing feet 2 extend on the base 7, the fixing feet 2 are arranged in parallel at the right upper corner of the base 7, the fixing device 3 is convenient to install, follow-up work is better completed, the structure is simple and reasonable, the fixing is firm, the weight of the selected materials is light, the transportation is convenient, and corrosion does not occur.
The shape of fixed foot 2 is the hexagonal prism, is equipped with on fixed foot 2 with the screw hole 9 on the fixing device 3 and the corresponding jack in pivot hole 10, and the base 7 is connected to the shorter base of its fixed foot 2, can make fixed foot 2 and the better cooperation of fixing device 3, and can realize the regulation of fixing device 3 angle to be applicable to the emergence of multiple condition, and the setting of structure does not have sharp-pointed edges and corners, improves the practicality.
The fixing device 3 is in a shape of a seven prism, the triangular head faces downwards, the flat head faces upwards, the clamping rod 5 is inserted into the jack 8 of the flat head part of the fixing device 3, nuts and screws are arranged at two ends of the clamping rod 5, the rotation is convenient, the angle of the fixing device 3 is convenient to adjust, the triangular head can ensure wider rotation range under the same volume, the flat head faces upwards, sharp edges are prevented, and the operation is convenient.
The fixed screw adopts a screw rod with the diameter of 0.6mm and a large screw head with the diameter of 3 mm; the clamping piece 12 is provided with two clamping pieces, the width and the thickness of the clamping pieces are 2.5mm, the position and the diameter of the selected fixing screw 6 are set, the screw is directly rotated by hands of a user, the rotation of a using instrument is avoided, the use is convenient, the clamping piece 12 is humanized, the size of the selected clamping piece 12 is set, the exposed visual field is small, the damage is small, and the clamping of the spine is convenient.
When the clamping piece 12 is bent towards the positive direction of the y axis, the bending inner diameter is 5mm, and the starting part of the clamping piece 12 is bent towards the negative direction of the y axis, so that the mouse can be conveniently fixed, the mouse can be effectively prevented from being extruded in the process of the clamping piece, the operation vision is not influenced, and meanwhile, the ganglion of the operation section can be fully exposed, so that the operation can be completed better.
The triangular prism grooves 13 are respectively arranged at the distal ends and the proximal ends of the two clamping pieces 12, the triangular prism grooves 13 and the clamping pieces 12 form an angle of 45 degrees, and two points and one line are formed when the upper section and the lower section of the operation section are clamped, so that the fixing effect is improved, the selected grooves are used for fixing transverse processes of the spine, and the setting of the angle of 45 degrees can allow the fixation of the spines with different lengths and sizes within a certain range.
During the use, can be earlier through rotating backbone holder 1 with the mouse backbone fixed, be convenient for find suitable operation angle, then make the better stability of support body through adjusting set screw 6, because the clamping piece 12 on backbone holder 1 is middle outside crooked, and just fix last section and the next section at the operation stage to can be abundant expose the visual field of operation, improve the effect of operation, the adoption of triangular prism recess 13 on the clamping piece has improved the fixed effect of mouse, and allows the fixed of different length size spines. When the operation is inconvenient, the angle of the fixing device 3 can be adjusted through the rotating shaft 4, so that the lateral position of the mouse can be better convenient for the operation implementation, and the mouse can well complete the work requirement.
The above embodiments are not to be taken as limiting the scope of the invention, and any alternatives or modifications to the embodiments of the invention will be apparent to those skilled in the art and fall within the scope of the invention.
The present invention is not described in detail in the present application, and is well known to those skilled in the art.
Claims (5)
1. The utility model provides a mouse lateral position vertebra fixed bolster, includes the fixed bolster main part that backbone holder, fixed leg and fixing device constitute, its characterized in that: the lower part of the spine clamp holder is arranged at one end of the clamping rod through a screw, and the other end of the clamping rod is connected with a jack on the fixing device; the two fixing feet are arranged and are integrated with the base, a rotating shaft is arranged on one side of each fixing foot, and a fixing screw is arranged above the rotating shaft; screw holes are formed in the side parts of the fixing device, and rotating shaft holes are formed below the screw holes; the rotating shaft penetrates through the rotating shaft hole to connect the upper part of the fixed foot with the upper part of the fixing device, and the lower part of the fixed foot and the lower part of the fixing device are fixed through the screw hole by a fixing screw; the spine clamp holder consists of a stud, a clamping piece, a triangular prism groove, a spring and an axle center fixing rod, wherein the axle center fixing rod is arranged below the stud, and the spine clamp holder is arranged at the upper end of the clamping rod under the cooperation of the stud and the axle center fixing rod; a spring is arranged on one side surface of the axle center fixing rod, a clamping piece is arranged on the spring, and a triangular prism groove is arranged on the clamping piece;
the fixing device is in a shape of a seven prism, the triangular head faces downwards, the flat head faces upwards, a clamping rod is inserted into a jack of the flat head part of the fixing device, and nuts and screws are arranged at two ends of the clamping rod;
When the clamping piece is bent towards the positive direction of the y axis, the bending inner diameter is 5mm, and the initial part of the clamping piece is bent towards the negative direction of the y axis.
2. A mouse lateral position spinal fixation support as claimed in claim 1, wherein: the base is a flat cuboid made of stainless steel, two fixing feet extend on the base, and the fixing feet are arranged in parallel at the right upper corner of the base.
3. A mouse lateral position spinal fixation support as claimed in claim 1, wherein: the shape of the fixing foot is a hexagonal prism, the fixing foot is provided with an inserting hole corresponding to the screw hole and the rotating shaft hole on the fixing device, and the shorter bottom edge of the fixing foot is connected with the base.
4. A mouse lateral position spinal fixation support as claimed in claim 1, wherein: the fixed screw adopts a screw rod with the diameter of 0.6mm and a large screw head with the diameter of 3 mm; the two clamping pieces are arranged, and the width and the thickness of the clamping pieces are 2.5mm.
5. A mouse lateral position spinal fixation support as claimed in claim 1, wherein: the triangular prism grooves are respectively arranged at the far ends and the near ends of the two clamping pieces, and the triangular prism grooves form an angle of 45 degrees with the clamping pieces.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018108036086 | 2018-07-20 | ||
| CN201810803608 | 2018-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109350292A CN109350292A (en) | 2019-02-19 |
| CN109350292B true CN109350292B (en) | 2024-06-04 |
Family
ID=65348896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811173685.4A Active CN109350292B (en) | 2018-07-20 | 2018-10-09 | Mouse lateral position vertebra fixed bolster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109350292B (en) |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2528400Y (en) * | 2001-05-16 | 2003-01-01 | 阎德强 | Bar-interlink articular orthotast |
| JP2004147966A (en) * | 2002-10-31 | 2004-05-27 | Shinatsupusu:Kk | Elevatable small-animal fixing implement |
| CN2691494Y (en) * | 2004-04-20 | 2005-04-13 | 上海市第二医科大学附属仁济医院 | Forceps for blocking prostatic blood vessel |
| EP1563805A2 (en) * | 2004-02-12 | 2005-08-17 | Rainer Frank | Device for fixing an animal |
| CN101063397A (en) * | 2006-04-28 | 2007-10-31 | 李根浚 | Sliding door |
| CN101084834A (en) * | 2006-06-09 | 2007-12-12 | 陈仕林 | Clamping apparatus for surgical suture operation |
| CN102189949A (en) * | 2010-03-17 | 2011-09-21 | 李尔公司 | Seat trim assembly |
| CN202389334U (en) * | 2011-12-21 | 2012-08-22 | 浙江吉利汽车研究院有限公司 | Limiting clamp for automobile safety belt |
| CN204600772U (en) * | 2015-03-16 | 2015-09-02 | 南通大学 | A kind of rodent spinal fixation system |
| CN104873289A (en) * | 2015-02-06 | 2015-09-02 | 张金辉 | Animal spinal fixator |
| CN207152672U (en) * | 2017-05-19 | 2018-03-30 | 哈尔滨商业大学 | A kind of rat spine operation fixing device |
-
2018
- 2018-10-09 CN CN201811173685.4A patent/CN109350292B/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2528400Y (en) * | 2001-05-16 | 2003-01-01 | 阎德强 | Bar-interlink articular orthotast |
| JP2004147966A (en) * | 2002-10-31 | 2004-05-27 | Shinatsupusu:Kk | Elevatable small-animal fixing implement |
| EP1563805A2 (en) * | 2004-02-12 | 2005-08-17 | Rainer Frank | Device for fixing an animal |
| CN2691494Y (en) * | 2004-04-20 | 2005-04-13 | 上海市第二医科大学附属仁济医院 | Forceps for blocking prostatic blood vessel |
| CN101063397A (en) * | 2006-04-28 | 2007-10-31 | 李根浚 | Sliding door |
| CN101084834A (en) * | 2006-06-09 | 2007-12-12 | 陈仕林 | Clamping apparatus for surgical suture operation |
| CN102189949A (en) * | 2010-03-17 | 2011-09-21 | 李尔公司 | Seat trim assembly |
| CN202389334U (en) * | 2011-12-21 | 2012-08-22 | 浙江吉利汽车研究院有限公司 | Limiting clamp for automobile safety belt |
| CN104873289A (en) * | 2015-02-06 | 2015-09-02 | 张金辉 | Animal spinal fixator |
| CN204600772U (en) * | 2015-03-16 | 2015-09-02 | 南通大学 | A kind of rodent spinal fixation system |
| CN207152672U (en) * | 2017-05-19 | 2018-03-30 | 哈尔滨商业大学 | A kind of rat spine operation fixing device |
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| Publication number | Publication date |
|---|---|
| CN109350292A (en) | 2019-02-19 |
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