CN109329938A - A kind of turmeric composition and preparation method thereof - Google Patents
A kind of turmeric composition and preparation method thereof Download PDFInfo
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- CN109329938A CN109329938A CN201811506103.XA CN201811506103A CN109329938A CN 109329938 A CN109329938 A CN 109329938A CN 201811506103 A CN201811506103 A CN 201811506103A CN 109329938 A CN109329938 A CN 109329938A
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- turmeric
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- curcumin
- vitamin
- tea saponin
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- 235000003392 Curcuma domestica Nutrition 0.000 title claims abstract description 72
- 235000003373 curcuma longa Nutrition 0.000 title claims abstract description 72
- 235000013976 turmeric Nutrition 0.000 title claims abstract description 72
- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 244000008991 Curcuma longa Species 0.000 title 1
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 71
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 45
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims abstract description 44
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 32
- 235000012754 curcumin Nutrition 0.000 claims abstract description 22
- 229940109262 curcumin Drugs 0.000 claims abstract description 22
- 239000004148 curcumin Substances 0.000 claims abstract description 22
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims abstract description 22
- 238000003756 stirring Methods 0.000 claims abstract description 21
- 235000011187 glycerol Nutrition 0.000 claims abstract description 19
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims abstract description 19
- 229930182490 saponin Natural products 0.000 claims abstract description 19
- 150000007949 saponins Chemical class 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 14
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000011709 vitamin E Substances 0.000 claims abstract description 14
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 14
- 229940046009 vitamin E Drugs 0.000 claims abstract description 14
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims abstract description 13
- 229940083466 soybean lecithin Drugs 0.000 claims abstract description 13
- NXMUXTAGFPJGTQ-UHFFFAOYSA-N decanoic acid;octanoic acid Chemical compound CCCCCCCC(O)=O.CCCCCCCCCC(O)=O NXMUXTAGFPJGTQ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 150000005691 triesters Chemical class 0.000 claims abstract description 12
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 8
- 239000008346 aqueous phase Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 11
- 239000006210 lotion Substances 0.000 claims description 6
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims description 6
- 238000000265 homogenisation Methods 0.000 claims description 5
- 238000010008 shearing Methods 0.000 claims description 5
- 229930003799 tocopherol Natural products 0.000 claims description 5
- 239000011732 tocopherol Substances 0.000 claims description 5
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 4
- 239000000845 maltitol Substances 0.000 claims description 4
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 4
- 235000010449 maltitol Nutrition 0.000 claims description 4
- 229940035436 maltitol Drugs 0.000 claims description 4
- 229960001295 tocopherol Drugs 0.000 claims description 4
- 235000010384 tocopherol Nutrition 0.000 claims description 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 4
- 239000001913 cellulose Substances 0.000 claims description 3
- 229920002678 cellulose Polymers 0.000 claims description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052698 phosphorus Inorganic materials 0.000 claims description 2
- 239000011574 phosphorus Substances 0.000 claims description 2
- 239000008347 soybean phospholipid Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 4
- 238000001816 cooling Methods 0.000 abstract description 2
- 238000004090 dissolution Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 238000004945 emulsification Methods 0.000 abstract 1
- 229960005150 glycerol Drugs 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 125000005456 glyceride group Chemical group 0.000 description 3
- 239000012071 phase Substances 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000010148 water-pollination Effects 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- JYTVKRNTTALBBZ-UHFFFAOYSA-N bis demethoxycurcumin Natural products C1=CC(O)=CC=C1C=CC(=O)CC(=O)C=CC1=CC=CC(O)=C1 JYTVKRNTTALBBZ-UHFFFAOYSA-N 0.000 description 1
- PREBVFJICNPEKM-YDWXAUTNSA-N bisdemethoxycurcumin Chemical compound C1=CC(O)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(O)C=C1 PREBVFJICNPEKM-YDWXAUTNSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- YXAKCQIIROBKOP-UHFFFAOYSA-N di-p-hydroxycinnamoylmethane Natural products C=1C=C(O)C=CC=1C=CC(=O)C=C(O)C=CC1=CC=C(O)C=C1 YXAKCQIIROBKOP-UHFFFAOYSA-N 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000009830 intercalation Methods 0.000 description 1
- 230000002687 intercalation Effects 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of turmeric composition and preparation method thereof, which has following raw material to be made: curcumin, vitamin E, soybean lecithin, Glycerin, mixed triester with caprylic acid capric acid, Tea Saponin, assistant for emulsifying agent and water.The turmeric composition is prepared by the following method to obtain: vitamin E and soybean lecithin being added after Glycerin, mixed triester with caprylic acid capric acid is preheated, curcumin is added after dissolution, continues stirring and is allowed to be completely dissolved, cooling is spare；Assistant for emulsifying agent, water and Tea Saponin are mixed evenly, turmeric solution is added after preheating, obtaining turmeric solution through homogeneous after high speed shear pre-emulsification is turmeric composition.The turmeric combination turmeric effect that the present invention obtains is good, and partial size and color value stability are high, and technique is easily realized.
Description
Technical field
The present invention relates to field of functional food, in particular to a kind of turmeric composition and preparation method thereof.
Background technique
Turmeric is a kind of zingiberaceous plant of integration of drinking and medicinal herbs, and curcumin is its most important effective component.Turmeric have turmeric,
It is anti-to be still drank after a night and other effects, but curcumin hydrophily and lipophilicity are poor, and solubility is extremely low in water and grease, limits turmeric
Therefore how the practical application of element is made the high water-soluble turmeric preparation of turmeric cellulose content and is widely studied.Such as patent
CN104286843A discloses a kind of preparation method of water-soluble curcumin powder, which is dissolved in MCT(i.e. for curcumin
Glycerin, mixed triester with caprylic acid capric acid) in, but because of the fat-soluble difference of turmeric, turmeric concentration is only 0.6-0.7% in MCT solution, and manufactured cream
In liquid MCT solution concentration be 20-30%, therefore in lotion turmeric concentration less than 0.3%.Patent CN106667912A is disclosed
A kind of preparation method of curcumin nano lotion, although the turmeric composition of 1-10nm partial size, the system can be prepared
Preparation Method is very high to equipment requirement, needs to close oxygen free condition, and needs moment (5S) heating and cooling between 30-200 DEG C,
General device is difficult to reach this condition.
Summary of the invention
In order to overcome the deficiencies of the prior art, the purpose of the present invention is to provide a kind of turmeric composition, the turmeric compositions
It is grouped as by the group of following mass percent meter:
Curcumin 1-5%, vitamin E 0.1-0.5%, soybean lecithin 1-2.5%, Glycerin, mixed triester with caprylic acid capric acid 10-20%, Tea Saponin 20-
40%, assistant for emulsifying agent 15-30%, surplus are water.
Wherein, turmeric cellulose content >=95wt% in the curcumin.
The vitamin E is the mixed tocopherols that content is 70-90%.
The phosphorus level in soya lecithin phosphatidylcholine content >=30wt%.
The assistant for emulsifying agent is glycerol, D-sorbite or maltitol.
Purity >=90wt% of the Tea Saponin.
The present invention also provides the preparation methods of above-mentioned turmeric composition, comprising the following steps:
(1) Glycerin, mixed triester with caprylic acid capric acid is preheated to 80-100 DEG C, soybean lecithin is added and vitamin E stirring and dissolving is added, added
Curcumin, continuing stirring is completely dissolved curcumin, obtains turmeric solution；
(2) water, assistant for emulsifying agent and Tea Saponin are mixed, is heated to 60 DEG C while stirring, continued stirring and become uniform liquid, obtain
To aqueous phase solution；
(3) high speed shear aqueous phase solution, and turmeric solution is slowly added in aqueous phase solution under conditions of shearing, it is molten to turmeric
After liquid is added, high speed shear is maintained, less than 2 μm, to obtain pre-emulsion to partial size；
(4) pre-emulsion is obtained into turmeric lotion, i.e. turmeric composition to average grain diameter < 500nm through high-pressure homogeneous；Processing condition are as follows:
Homogenization pressure 30-50Mpa, 60-70 DEG C of temperature.
Turmeric composition of the invention has the advantage that
(1) as previously described, the hydrophily and lipophilicity of turmeric are poor, and Glycerin, mixed triester with caprylic acid capric acid is used as conventionally used for dissolving rouge
The solvent of soluble components, it is very limited to the solvability of turmeric, through testing, dissolution 5% is only capable of under normal condition, and dissolve temperature
Degree need to reach 150-160 DEG C.During preparing turmeric composition, having used soybean lecithin, (phosphatidyl choline contains the present invention
Amount >=30wt%), so that curcumin is dissolved in Glycerin, mixed triester with caprylic acid capric acid that turmeric is made is molten at a lower temperature (80-100 DEG C)
Liquid reduces the decomposition of curcumin at high temperature；
(2) turmeric composition of the invention has very strong sober-up function.Tea Saponin is a kind of saponin(e extracted from tea seed
Class compound, Tea Saponin are the inhibitor of alcohol absorption and the promotor of alcohol digestion in alcohol absorption metabolism, have protection
The function of liver, compatibility is used in combination with stronger antialcoholism function by a certain percentage with turmeric；
(3) the problem of present invention also solves turmeric emulsion intercalation method using Tea Saponin.The present invention is using Tea Saponin and helps cream
Stable water-soluble lotion is made in the oily two insoluble turmerics of water by agent (glycerol, D-sorbite or maltitol), and is stablized
Property it is high, place at normal temperature 18 months, place for 37 DEG C and do not occur within 9 months a problem that oil slick, layering, partial size and color value are basic
It remains unchanged.
Specific embodiment
Below in conjunction with specific example, the following further describes the technical solution of the present invention.
Embodiment 1
A kind of turmeric composition, composed of the following components:
Curcumin 10g, vitamin E (90% mixed tocopherol) 1g, soybean lecithin (phosphatidylcholine content 35wt%) 10g, the pungent last of the ten Heavenly stems
Acid glyceride 10g, Tea Saponin 200g, glycerol 150g, water 619g.
The above turmeric composition the preparation method is as follows:
(1) Glycerin, mixed triester with caprylic acid capric acid is preheated to 80 DEG C, soybean lecithin is added and vitamin E stirring and dissolving is added, add turmeric
Element, continuing stirring is completely dissolved curcumin, obtains turmeric solution；
(2) water, glycerol and Tea Saponin are mixed, is heated to 60 DEG C while stirring, continued stirring and become uniform liquid, obtain water
Phase solution；
(3) high speed shear aqueous phase solution, and turmeric solution is slowly added in aqueous phase solution under conditions of shearing, it is molten to turmeric
After liquid is added, high speed shear is maintained, less than 2 μm, to obtain pre-emulsion to partial size；
(4) pre-emulsion is high-pressure homogeneous under the conditions of homogenization pressure 30Mpa, temperature 60 C to obtain turmeric group to average grain diameter 241nm
Close object.
Embodiment 2
A kind of turmeric composition, composed of the following components:
Curcumin 50g, vitamin E (70% mixed tocopherol) 5g, soybean lecithin (phosphatidylcholine content 32wt%) 25g, the pungent last of the ten Heavenly stems
Acid glyceride 200g, Tea Saponin 400g, D-sorbite 300g, water 20g.
The above turmeric composition the preparation method is as follows:
(1) Glycerin, mixed triester with caprylic acid capric acid is preheated to 100 DEG C, soybean lecithin is added and vitamin E stirring and dissolving is added, add turmeric
Element, continuing stirring is completely dissolved curcumin, obtains turmeric solution；
(2) water, glycerol and Tea Saponin are mixed, is heated to 60 DEG C while stirring, continued stirring and become uniform liquid, obtain water
Phase solution；
(3) high speed shear aqueous phase solution, and turmeric solution is slowly added in aqueous phase solution under conditions of shearing, it is molten to turmeric
After liquid is added, high speed shear is maintained, less than 2 μm, to obtain pre-emulsion to partial size；
(4) pre-emulsion is high-pressure homogeneous under the conditions of homogenization pressure 50Mpa, temperature 70 C to obtain turmeric group to average grain diameter 256nm
Close object.
Embodiment 3
A kind of turmeric composition, composed of the following components:
Bisdemethoxycurcumin 0g, vitamin E (80% mixed tocopherol) 3g, soybean lecithin (phosphatidylcholine content 32wt%) 12g, the pungent last of the ten Heavenly stems
Acid glyceride 150g, Tea Saponin 300g, maltitol 200g, water 305g
The above turmeric composition the preparation method is as follows:
(1) Glycerin, mixed triester with caprylic acid capric acid is preheated to 90 DEG C, soybean lecithin is added and vitamin E stirring and dissolving is added, add turmeric
Element, continuing stirring is completely dissolved curcumin, obtains turmeric solution；
(2) water, glycerol and Tea Saponin are mixed, is heated to 60 DEG C while stirring, continued stirring and become uniform liquid, obtain water
Phase solution；
(3) high speed shear aqueous phase solution, and turmeric solution is slowly added in aqueous phase solution under conditions of shearing, it is molten to turmeric
After liquid is added, high speed shear is maintained, less than 2 μm, to obtain pre-emulsion to partial size；
(4) pre-emulsion is high-pressure homogeneous under the conditions of homogenization pressure 40Mpa, temperature 70 C to obtain turmeric group to average grain diameter 221nm
Close object.
Embodiment 1-3 obtain 4 DEG C of lotion are stored 24 months, and room temperature is stored 18 months, and 55 DEG C are stored 6 months, no layering,
Without oil slick, partial size is stablized without significant changes, color value, and it is as shown in table 1 to compare effect with commercial samples:
The steadiness of 1 embodiment 1-3 of table and commercial samples
Claims (7)
1. a kind of turmeric composition, it is characterised in that be grouped as by the group of following mass percent meter: curcumin 1-5%, vitamin
E 0.1-0.5%, soybean lecithin 1-2.5%, Glycerin, mixed triester with caprylic acid capric acid 10-20%, Tea Saponin 20-40%, assistant for emulsifying agent 15-30%, surplus
For water.
2. turmeric composition according to claim 1, it is characterised in that turmeric cellulose content in the curcumin >=
95wt%。
3. turmeric composition according to claim 1, it is characterised in that the vitamin E is the day that content is 70-90%
Right mixed tocopherol.
4. turmeric composition according to claim 1, it is characterised in that the phosphorus level in soya lecithin phosphatidylcholine content
≥30wt%。
5. turmeric composition according to claim 1, it is characterised in that the assistant for emulsifying agent be glycerol, D-sorbite or
Maltitol.
6. turmeric composition according to claim 1, it is characterised in that purity >=90wt% of the Tea Saponin.
7. a kind of preparation method of turmeric composition as described in claim 1, it is characterised in that the following steps are included:
(1) Glycerin, mixed triester with caprylic acid capric acid is preheated to 80-100 DEG C, soybean lecithin is added and vitamin E stirring and dissolving is added, added
Curcumin, continuing stirring is completely dissolved curcumin, obtains turmeric solution；
(2) water, assistant for emulsifying agent and Tea Saponin are mixed, is heated to 60 DEG C while stirring, continued stirring and become uniform liquid, obtain
To aqueous phase solution；
(3) high speed shear aqueous phase solution, and turmeric solution is slowly added in aqueous phase solution under conditions of shearing, it is molten to turmeric
After liquid is added, high speed shear is maintained, less than 2 μm, to obtain pre-emulsion to partial size；
(4) pre-emulsion is obtained into turmeric lotion, i.e. turmeric composition to average grain diameter < 500nm through high-pressure homogeneous；Processing condition are as follows:
Homogenization pressure 30-50Mpa, 60-70 DEG C of temperature.
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| CN111481524A (en) * | 2020-03-31 | 2020-08-04 | 右江民族医学院 | Curcumin microencapsulation method |
| CN111494334A (en) * | 2020-03-31 | 2020-08-07 | 右江民族医学院 | Method for preparing linarin microcapsule particles |
| CN112602875A (en) * | 2020-12-24 | 2021-04-06 | 吉林大学 | Method for preparing food-grade nano emulsion coated with photosensitizer |
| CN113117091A (en) * | 2019-12-30 | 2021-07-16 | 晨光生物科技集团股份有限公司 | Curcumin water-soluble preparation and preparation method thereof |
| CN113383881A (en) * | 2021-04-30 | 2021-09-14 | 河南中大恒源生物科技股份有限公司 | Liquid water-soluble curcumin, and preparation method and application thereof |
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| CN113117091B (en) * | 2019-12-30 | 2022-11-25 | 晨光生物科技集团股份有限公司 | Curcumin water-soluble preparation and preparation method thereof |
| CN111481524A (en) * | 2020-03-31 | 2020-08-04 | 右江民族医学院 | Curcumin microencapsulation method |
| CN111494334A (en) * | 2020-03-31 | 2020-08-07 | 右江民族医学院 | Method for preparing linarin microcapsule particles |
| CN112602875A (en) * | 2020-12-24 | 2021-04-06 | 吉林大学 | Method for preparing food-grade nano emulsion coated with photosensitizer |
| CN113383881A (en) * | 2021-04-30 | 2021-09-14 | 河南中大恒源生物科技股份有限公司 | Liquid water-soluble curcumin, and preparation method and application thereof |
| CN113383881B (en) * | 2021-04-30 | 2023-08-29 | 河南中大恒源生物科技股份有限公司 | Liquid water-soluble curcumin and preparation method and application thereof |
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