CN109303822A - A kind of Chinese medicine preparation and preparation method thereof for treating lumbar vertebrae hyperosteogeny - Google Patents

A kind of Chinese medicine preparation and preparation method thereof for treating lumbar vertebrae hyperosteogeny Download PDF

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CN109303822A
CN109303822A CN201811426639.0A CN201811426639A CN109303822A CN 109303822 A CN109303822 A CN 109303822A CN 201811426639 A CN201811426639 A CN 201811426639A CN 109303822 A CN109303822 A CN 109303822A
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chinese medicine
lumbar vertebrae
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vertebrae hyperosteogeny
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刘德胜
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine preparations and preparation method thereof for treating lumbar vertebrae hyperosteogeny, formula includes consisting of part: loosestrife: 200-400g, polygonum cuspidate: 200-300g, lycopodium calvatum: 50-80g, heavy snow rattan: 40-100g, uncaria: 45-80g, Cortex Eucommiae: 100-125g, Rhizoma Chuanxiong: 8-15g, safflower: 5-15g, endothelium corneum gigeriae galli: 200-250g, egg with green shell: 4-8, Shanxi mature vinegar: 1000-2000g, white wine: 2000-4000g.Preparation method includes the following steps: (1) mixing (2) and decoct (3) immersion (4) filtering: step (3) being impregnated resulting soak and are filtered, are uniformly mixed, and packed.Chinese medicine prepared by preparation method of the present invention has the features such as formula is simple, and at low cost, good effect is uneasy to recur, Small side effects.45 patients are taken, efficient up to 88.9%, cure rate is up to 82.2%.

Description

A kind of Chinese medicine preparation and preparation method thereof for treating lumbar vertebrae hyperosteogeny
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine preparation for treating lumbar vertebrae hyperosteogeny and its preparation side Method.
Background technique
The Etiological of lumbar vertebrae hyperosteogeny and the retrogression pathological changes of articular cartilage are related, the osteoproliferation of lumbar vertebrae be because After middle age, with the increase at age, each histiocytic physiological function of body also gradually fails aging, the interverbebral disc of degeneration by Moisture content is gradually lost, narrowing of intervertebral space, to periphery bulging, centrum is unstable for fibrous ring relaxation, and fibrous ring is torn outside vertebral rim It splits, leads to the protrusion of nucleus pulposus, the periosteum of posterior longitudinal ligament is jacked up, generate new bone below, form spur or osteoproliferation.Also have After people thinks intervertebral disc degeneration atrophy, centrum turns forward, and anterior margin of vertebral body is hindered in middle line by anterior longitudinal ligament, and two sides periosteum lifts It rises, subperiosteum forms new bone.In addition, the compression factor of part is also to cause the principal element of osteoproliferation.
There are operation, massage traction and medicinal treatment to the treatment of lumbar hyperosteogency at present.Treat hyperostosis Surgery cost is relatively high, and curative effect is difficult to ensure again, can also increase old and frail patient the risk of operation;Massage traction is Physical damage is carried out to hyperplasia by external force, patient will endure huge pain, and this local treatment is ignored to people The adjusting of body-internal-circulation entirety, therefore can only also play temporary alleviation.The drug for the treatment of osteoproliferation mainly has Chinese medicine at present With two kinds of Western medicine, Western medicine is usually some analgesic-antipyretic, there is no effective therapeutic agent for osteoproliferation.Chinese medicine again can be with Be divided into two major classes: plaster and Chinese drugs agentia, plaster coating temporary can only generally relieve pain, once ailing just meeting again of being discontinued Recurrence;Existing traditional Chinese medicine for oral administration, effect is unobvious, high recurrence rate.
Summary of the invention
For the problem that exists in the prior art, the present invention provides a kind of Chinese medicine preparation and its medicine for treating lumbar vertebrae hyperosteogeny The advantages such as method for preparing medicated wine has effect good, quick, and recurrence rate is low.
The present invention treats the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, including consisting of part: loosestrife: 200-400 parts, tiger Cane: 200-300 parts, lycopodium calvatum: 50-80 parts, heavy snow rattan: 40-100 parts, uncaria: 45-80 parts, Cortex Eucommiae: 100-125 parts, Rhizoma Chuanxiong: 8-15 parts, safflower: 5-15 parts, endothelium corneum gigeriae galli: 200-250 parts, egg with green shell: 4-8, vinegar: 1000-2000 parts, white wine: 2000-4000 parts.
It is preferred that including consisting of part: loosestrife: 300 parts, polygonum cuspidate: 260 parts, lycopodium calvatum: 60 parts, heavy snow rattan: 60 Part, uncaria: 60 parts, Cortex Eucommiae: 110 parts, Rhizoma Chuanxiong: 10 parts, safflower: 10 parts, endothelium corneum gigeriae galli: 230 parts, egg with green shell: 5, vinegar: 1500 parts, white wine: 2500 parts.
It is preferred that white wine is 45-50 ° of pure maize wine.
It is preferred that vinegar is Shanxi mature vinegar.
The present invention treats the preparation method of the Chinese medicine of lumbar vertebrae hyperosteogeny, comprising the following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, chicken by formula Interior gold, is then uniformly mixed, and obtains Traditional Chinese drug mixture;
(2) it decocts: above-mentioned deal white wine is added in step (1) Traditional Chinese drug mixture, at 60-80 DEG C, carry out boiling 0.5- 1h, cooled to room temperature;
(3) it impregnates: the vinegar of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture, and add Enter egg with green shell, impregnates 10-15 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
The present invention it is achieved compared with the existing technology the utility model has the advantages that treatment lumbar vertebrae hyperosteogeny of the invention middle medical instrument There is the features such as formula is simple, and at low cost, good effect is uneasy to recur, Small side effects.45 patients are taken, effective percentage reaches 88.9%, cure rate is up to 82.2%.
Specific embodiment
Embodiment 1
The present invention treats the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, including consisting of part: loosestrife: 300g, polygonum cuspidate: 260g, lycopodium calvatum: 60g, heavy snow rattan: 60g, uncaria: 60g, Cortex Eucommiae: 110g, Rhizoma Chuanxiong: 10g, safflower: 10g, endothelium corneum gigeriae galli: 230g, egg with green shell: 5, Shanxi mature vinegar: 1500g, 45-50 ° of pure maize wine: 2500g.
The preparation method for treating the Chinese medicine of lumbar vertebrae hyperosteogeny, comprising the following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, chicken by formula Interior gold, is then uniformly mixed, and obtains Traditional Chinese drug mixture;
(2) it decocts: the above-mentioned pure maize white wine of deal is added in step (1) Traditional Chinese drug mixture, at 65 DEG C, boiling 1h, from So it is cooled to room temperature;
(3) it impregnates: the Shanxi Lao Chen of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture Vinegar, and egg with green shell is added, it impregnates 15 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
Embodiment 2
The present invention treats the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, including consisting of part: loosestrife: 250g, polygonum cuspidate: 300g, lycopodium calvatum: 80g, heavy snow rattan: 80g, uncaria: 80g, Cortex Eucommiae: 100g, Rhizoma Chuanxiong: 15g, safflower: 5g, endothelium corneum gigeriae galli: 250g, Egg with green shell: 4, vinegar: 1000g, white wine: 2000g.
The preparation method for treating the Chinese medicine of lumbar vertebrae hyperosteogeny, comprising the following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, chicken by formula Interior gold, is then uniformly mixed, and obtains Traditional Chinese drug mixture;
(2) it decocts: above-mentioned deal white wine is added in step (1) Traditional Chinese drug mixture, at 60 DEG C, boiling 1h, natural cooling To room temperature;
(3) it impregnates: the vinegar of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture, and add Enter egg with green shell, impregnates 12 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
Embodiment 3
The present invention treats the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, including consisting of part: loosestrife: 400g, polygonum cuspidate: 300g, lycopodium calvatum: 50g, heavy snow rattan: 60g, uncaria: 50g, Cortex Eucommiae: 125g, Rhizoma Chuanxiong: 15g, safflower: 10g, endothelium corneum gigeriae galli: 250g, egg with green shell: 5, vinegar: 2000g, white wine: 3000g.
The preparation method for treating the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, comprising the following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, chicken by formula Interior gold, is then uniformly mixed, and obtains Traditional Chinese drug mixture;
(2) it decocts: above-mentioned deal white wine is added in step (1) Traditional Chinese drug mixture, at 70 DEG C, it is natural to carry out boiling 0.5h It is cooled to room temperature;
(3) it impregnates: the vinegar of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture, and add Enter egg with green shell, impregnates 10 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
Embodiment 4
The present invention treats the Chinese medicine preparation of lumbar vertebrae hyperosteogeny, including consisting of part: loosestrife: 400g, polygonum cuspidate: 200g, lycopodium calvatum: 80g, heavy snow rattan: 60g, uncaria: 45g, Cortex Eucommiae: 120g, Rhizoma Chuanxiong: 8g, safflower: 15g, endothelium corneum gigeriae galli: 200g, Egg with green shell: 8, vinegar: 1500g, white wine: 2200g.
The preparation method for treating the Chinese medicine of lumbar vertebrae hyperosteogeny, comprising the following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, chicken by formula Interior gold, is then uniformly mixed, and obtains Traditional Chinese drug mixture;
(2) it decocts: above-mentioned deal white wine is added in step (1) Traditional Chinese drug mixture, at 80 DEG C, boiling 0.5h is naturally cold But to room temperature;
(3) it impregnates: the vinegar of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture, and add Enter egg with green shell, impregnates 15 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
Embodiment 5
Case 1:
Wu, male, 55 years old, Guizhou Pan Zhou people was diagnosed as lumbar vertebrae hyperosteogeny through Pan county the People's Hospital, is matched using the present invention Recipe wine, daily 25-40g, state of getting well for 3 months has been eaten, the existing several years does not recur.Case 2
Zhang, female, 49 years old, Guizhou Pan Zhou people was diagnosed as lumbar vertebrae hyperosteogeny through Pan county the People's Hospital, is matched using the present invention Recipe wine, daily 15-30g have eaten 2 half a months and have got well state, and the existing several years does not recur.Case 3:
Dai, male, 59 years old, Guizhou Pan Zhou people was diagnosed as lumbar vertebrae hyperosteogeny through Pan county the People's Hospital, is matched using the present invention Recipe wine, daily 25-40g have eaten state of getting well for 4 months, and the existing several years does not recur.Case 4
Tang, female, 53 years old, Guizhou Pan Zhou people was diagnosed as lumbar vertebrae hyperosteogeny through Pan county the People's Hospital, is matched using the present invention Recipe wine, daily 15-30g have eaten 1 half a month and have got well state, and the existing several years does not recur.

Claims (5)

1. a kind of Chinese medicine preparation for treating lumbar vertebrae hyperosteogeny, it is characterised in that: including consisting of part: loosestrife: 200- 400 parts, polygonum cuspidate: 200-300 parts, lycopodium calvatum: 50-80 parts, heavy snow rattan: 40-100 parts, uncaria: 45-80 parts, Cortex Eucommiae: 100-125 Part, Rhizoma Chuanxiong: 8-15 parts, safflower: 5-15 parts, endothelium corneum gigeriae galli: 200-250 parts, egg with green shell: 4-8, vinegar: 1000-2000 parts, White wine: 2000-4000 parts.
2. a kind of Chinese medicine preparation for treating lumbar vertebrae hyperosteogeny according to claim 1, it is characterised in that: including with the following group At part: loosestrife: 300 parts, polygonum cuspidate: 260 parts, lycopodium calvatum: 60 parts, heavy snow rattan: 60 parts, uncaria: 60 parts, Cortex Eucommiae: 110 parts, Rhizoma Chuanxiong: 10 parts, safflower: 10 parts, endothelium corneum gigeriae galli: 230 parts, egg with green shell: 5, vinegar: 1500 parts, white wine: 2500 parts.
3. a kind of Chinese medicine preparation for treating lumbar vertebrae hyperosteogeny according to claim 1, it is characterised in that: white wine 45- 50 ° of pure maize wine.
4. a kind of Chinese medicine preparation for treating lumbar vertebrae hyperosteogeny according to claim 1, it is characterised in that: vinegar is that Shanxi is old Mature vinegar.
5. a kind of preparation method of Chinese medicine for treating lumbar vertebrae hyperosteogeny according to claim 1, it is characterised in that: including Following steps:
(1) it mixes: weighing loosestrife, polygonum cuspidate, lycopodium calvatum, heavy snow rattan, uncaria, Cortex Eucommiae, Rhizoma Chuanxiong, safflower, endothelium corneum gigeriae galli by formula, Then it is uniformly mixed, obtains Traditional Chinese drug mixture;
(2) it decocts: above-mentioned deal white wine is added in step (1) Traditional Chinese drug mixture, at 60-80 DEG C, carry out boiling 0.5-1h certainly So it is cooled to room temperature;
(3) it impregnates: the vinegar of above-mentioned deal will be added in the decoction mixture of step (2) resulting Traditional Chinese drug mixture, and be added green Shell egg impregnates 10-15 days;
(4) it filters: step (3) being impregnated into resulting soak and are filtered, are uniformly mixed, sterilization, and packed.
CN201811426639.0A 2018-11-27 2018-11-27 A kind of Chinese medicine preparation and preparation method thereof for treating lumbar vertebrae hyperosteogeny Pending CN109303822A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108310085A (en) * 2018-04-13 2018-07-24 杜闯明 A kind of Chinese medicine preparation that treating osteoproliferation and its medicinal liquor preparation method

Citations (4)

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Publication number Priority date Publication date Assignee Title
CN1269402A (en) * 1999-04-01 2000-10-11 宋栋梁 Chiense herbal medicine wine
CN102451370A (en) * 2010-10-21 2012-05-16 金明 Traditional Chinese medicine wine for treating rheumatism and impediment pain
CN103751522A (en) * 2011-10-18 2014-04-30 虞兴涛 Traditional Chinese medicinal wine for treating rheumatism
CN108310085A (en) * 2018-04-13 2018-07-24 杜闯明 A kind of Chinese medicine preparation that treating osteoproliferation and its medicinal liquor preparation method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269402A (en) * 1999-04-01 2000-10-11 宋栋梁 Chiense herbal medicine wine
CN102451370A (en) * 2010-10-21 2012-05-16 金明 Traditional Chinese medicine wine for treating rheumatism and impediment pain
CN103751522A (en) * 2011-10-18 2014-04-30 虞兴涛 Traditional Chinese medicinal wine for treating rheumatism
CN108310085A (en) * 2018-04-13 2018-07-24 杜闯明 A kind of Chinese medicine preparation that treating osteoproliferation and its medicinal liquor preparation method

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108310085A (en) * 2018-04-13 2018-07-24 杜闯明 A kind of Chinese medicine preparation that treating osteoproliferation and its medicinal liquor preparation method

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