CN109270278A - A kind of discharging of waste liquid control method and coaglation analyzer - Google Patents
A kind of discharging of waste liquid control method and coaglation analyzer Download PDFInfo
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- CN109270278A CN109270278A CN201811133646.1A CN201811133646A CN109270278A CN 109270278 A CN109270278 A CN 109270278A CN 201811133646 A CN201811133646 A CN 201811133646A CN 109270278 A CN109270278 A CN 109270278A
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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Abstract
This application provides a kind of discharging of waste liquid control method and coaglation analyzer, using the buffer storage function of waste liquid buffer container, so that waste liquid contains, container carries out replacement or when waste liquid is removed is online without suspending new samples, to improve measurement efficiency.The embodiment of the present application method includes: to obtain cleaning solution by cleaning liquid receptacle；Specimen needle and/or reagent needle are cleaned using cleaning solution, generate waste liquid；It controls waste liquid and waste liquid buffer container is emitted by pipeline；Discharging of waste liquid to the waste liquid of control waste liquid buffer container contains container.
Description
Technical field
This application involves coaglation analyzer field more particularly to a kind of discharging of waste liquid control method and coaglation analyzers.
Background technique
Coaglation analyzer generally carries out the compressing of sample or reagent using specimen needle or reagent needle.For avoid specimen needle or
The caused cross contamination in compressing difference sample or reagent of reagent needle completes respective sample or reagent in specimen needle or reagent needle
Compressing after need to be moved into corresponding service sink and cleaned, the waste liquid that when cleaning generates needs to be discharged to waste liquid in time
Bucket, in order to avoid cause biological pollution.
After the waste liquid of waste liquid barrel is filled, when needing replacing waste liquid barrel, it is online and stop testing, shadow that new samples can only be suspended
Ring measurement efficiency and user experience.
Summary of the invention
This application provides a kind of discharging of waste liquid control method and coaglation analyzers, are stored up using the buffering of waste liquid buffer container
Function is deposited, so that waste liquid contains container when carrying out replacement or waste liquid is removed it is not necessary that suspend new samples online, to improve survey
Amount efficiency.
The application first aspect provides a kind of discharging of waste liquid control method, is applied to coagulo meter, and the coagulo meter includes clear
Clean liquid container, specimen needle and/or reagent needle, waste liquid buffer container and waste liquid contain container, which comprises
Cleaning solution is obtained by the cleaning liquid receptacle；
The specimen needle and/or reagent needle are cleaned using the cleaning solution, generate waste liquid；
It controls the waste liquid and the waste liquid buffer container is emitted by pipeline；
Discharging of waste liquid to the waste liquid for controlling the waste liquid buffer container contains container.
In conjunction with the application in a first aspect, in the first possible implementation, the control waste liquid buffer container
Discharging of waste liquid to the waste liquid contains container, comprising:
Whether the waste liquid liquid measure for monitoring the waste liquid buffer container reaches preset threshold；
If the waste liquid liquid measure of the waste liquid buffer container reaches preset threshold, the waste liquid row of the waste liquid buffer container is controlled
It puts to the waste liquid and contains container.
In conjunction with the application in a first aspect, in second of possible implementation, the control waste liquid buffer container
Discharging of waste liquid to the waste liquid contains container, comprising:
Whether the waste liquid liquid measure for monitoring the waste liquid buffer container reaches preset threshold；
If the waste liquid liquid measure of the waste liquid buffer container reaches preset threshold, the waste liquid liquid that the waste liquid contains container is monitored
Whether amount reaches the first limit value；
If the waste liquid liquid measure that the waste liquid contains container is not up to the first limit value, the useless of the waste liquid buffer container is controlled
Liquid is emitted into the waste liquid and contains container.
In conjunction with the application first aspect or the first to any of second possible implementation, the third is possible
In implementation, the waste liquid buffer container and the waste liquid contain and are provided with waste drains pump on the pipeline between container, described useless
Liquid pump controls the discharge of the waste liquid of the waste liquid buffer container.
In conjunction with the third possible implementation of the application first aspect, in the 4th kind of possible implementation, the control
Discharging of waste liquid to the waste liquid for making the waste liquid buffer container contains container, comprising:
The unlatching setting duration for controlling the waste drains pump, so that the discharging of waste liquid of the waste liquid buffer container gives up to described
Liquid contains container.
In conjunction with second of possible implementation of the application first aspect, in the 5th kind of possible implementation, the side
Method further include:
If the waste liquid liquid measure that the waste liquid contains container reaches the first limit value, newly generated waste liquid is stored in described useless
Liquid buffer container forbids the newly generated discharging of waste liquid to the waste liquid to contain container, and issues the prompt letter of fully loaded failure
Breath.
In conjunction with the 5th kind of possible implementation of the application first aspect, in the 6th kind of possible implementation, the hair
It has after the prompt information of fully loaded failure, further includes:
When online new samples quantity reaches setting quantity, monitor whether the fully loaded failure is eliminated；
If the fully loaded failure is not eliminated, suspend the online of new samples；
If the fully loaded failure has been eliminated, allow the online of new samples.
In conjunction with the 6th kind of possible implementation of the application first aspect, in the 7th kind of possible implementation, the prison
Survey whether the fully loaded failure is eliminated, comprising:
It monitors the waste liquid and contains container and whether be changed to new waste liquid and contain container；
If the waste liquid contains container when being changed to new waste liquid and containing container, it is judged as the fully loaded Failure elimination.
In conjunction with the 6th kind of possible implementation of the application first aspect, in the 8th kind of possible implementation, the side
Method further include:
If the waste liquid contains container when being changed to new waste liquid and containing container, the waste liquid that the new waste liquid contains container is monitored
Whether liquid measure is lower than the second limit value；
If the new waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that the fully loaded failure does not disappear
It removes；
If the new waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as the fully loaded Failure elimination.
In conjunction with the 6th kind of possible implementation of the application first aspect, in the 9th kind of possible implementation, the side
Method further include:
If the waste liquid contains container when not being changed to new waste liquid and containing container, the liquid measure that the waste liquid contains container is monitored
Whether the second limit value is lower than；
If the waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that the fully loaded failure does not disappear
It removes；
If the waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as the fully loaded Failure elimination.
In conjunction with second of possible implementation of the application first aspect, in the tenth kind of possible implementation, the side
Method further include:
When monitoring that the waste liquid contains the waste liquid liquid measure of container and reaches the first limit value, online new samples are carried out
It counts, the new samples for allowing to set quantity are online.
In conjunction with the application first aspect or the first to any of the tenth kind possible implementation, a kind of the tenth possibility
Implementation in, the waste liquid buffer container be equipped with overflow port, the method also includes:
Container is contained when the waste liquid of the waste liquid buffer container cannot be discharged into the waste liquid from the waste liquid buffer container
When, then when the liquid level of waste liquid in the waste liquid buffer container is when being higher than the overflow port, waste liquid is flowed out from the overflow port.
In conjunction with a kind of possible implementation of the application first aspect the tenth, in the 12nd kind of possible implementation, institute
State that overflow port contains container by waste liquid described in piping connection, and/or spare waste liquid contains container, and/or spare waste liquid buffers
Container and/or waste liquid pool, the method also includes:
The waste liquid of the waste liquid buffer container is emitted into the waste liquid from overflow port outflow and contains container, and/or institute
It states spare waste liquid and contains container, and/or the spare waste liquid buffer container and/or the waste liquid pool.
The application second aspect also provides a kind of coaglation analyzer characterized by comprising at least one reaction vessel,
For providing reacting environment for sample and reagent；Hemostasis detestion device, for carrying out blood coagulation inspection to through reagent treated sample
It surveys, obtains the electrical signal information of reflection solidification situation；Processor, for receiving and processing the electricity of the hemostasis detestion device output
Signal message, to obtain the measurement parameter of sample；Wherein, the processor is also used to execute according to any of the above-described embodiment
The discharging of waste liquid control method.
In conclusion needing to hold by cleaning solution after specimen needle or reagent needle complete the compressing of respective sample or reagent
Device obtains cleaning solution, is cleaned using cleaning solution to specimen needle and/or reagent needle, generates waste liquid, first controls discharging of waste liquid extremely
Waste liquid buffer container, then control discharging of waste liquid to the waste liquid of waste liquid buffer container and contain container, since waste liquid buffer container provides
The buffer storage function of waste liquid is carried out replacement or when waste liquid is removed, is buffered using waste liquid so as to contain container in waste liquid
The buffer storage function of container can achieve the purpose that it is not necessary that suspend new samples online, to improve measuring speed.
Detailed description of the invention
Fig. 1 is one embodiment flow diagram of the discharging of waste liquid control method of the application；
Fig. 2 is the structural schematic diagram of the liquid channel system of the coagulo meter of some embodiments of the application；
Fig. 3 is the structural schematic diagram of the waste liquid buffer container of some embodiments of the application；
Fig. 4 is the structural schematic diagram of the float level meter of some embodiments of the application；
Fig. 5 is the flow diagram of the discharging of waste liquid of the control waste liquid buffer container of some embodiments of the application；
Flow diagram Fig. 6 online for the new samples after the fully loaded failure of some embodiments of the application；
Fig. 7 is the structural schematic diagram of the discharging of waste liquid control system of some embodiments of the application；
Fig. 8 is the structural schematic diagram of the discharging of waste liquid control system of some embodiments of the application；
Fig. 9 is the structural schematic diagram of the discharging of waste liquid control system of some embodiments of the application；
Figure 10 is the structural schematic diagram of the discharging of waste liquid control system of some embodiments of the application；
Figure 11 is the structural schematic diagram of the discharging of waste liquid control system of some embodiments of the application.
Specific embodiment
This application provides a kind of discharging of waste liquid control methods, using the buffer storage function of waste liquid buffer container, so that
Waste liquid contains container and carries out replacement or when waste liquid is removed it is not necessary that suspend new samples online, to improve measurement efficiency.
Referring to Fig. 1, the embodiment of the present application provides a kind of discharging of waste liquid control method, it is applied in coagulo meter, comprising:
Step 101 obtains cleaning solution by cleaning liquid receptacle.
In the present embodiment, by the structure of the liquid channel system of coagulo meter shown in Fig. 2, to describe discharging of waste liquid control method
It is how from cleaning liquid receptacle to obtain cleaning solution, the liquid channel system of coagulo meter mainly includes that cleaning liquid receptacle 201, cleaning solution are slow
Rush container 202, specimen needle 203, sample needle injection 204, specimen needle cleaning device 205, reagent needle 206, reagent needle injection
207, reagent needle cleaning device 208, waste liquid buffer container 209, waste liquid contain container 210, power component 211-216, valve
217 and 218 and various pipe fittings and pipeline etc..Sample needle injection 204 is used to control the compressing movement of the specimen needle, examination
Agent needle injection 207 is used to control the compressing movement of reagent needle.Power component is the device for controlling liquid flowing, can be with
It is pump, e.g. diaphragm pump or peristaltic pump.Valve 217 and 218 can be solenoid valve, below by taking solenoid valve as an example.
Cleaning liquid receptacle 201 successively with power component 211, cleaning solution buffer container 202, power component 212, electromagnetism
Valve 217, sample needle injection 204, specimen needle 203 pass through related pipe fitting and connect with pipeline formation fluid path, specimen needle cleaning dress
It sets 205 and successively contains container 210 with power component 214, waste liquid buffer container 209, power component 216, waste liquid and pass through phase
Pipe fitting is closed to connect with pipeline formation fluid path.Cleaning liquid receptacle 201 provides cleaning solution to clean to specimen needle 203, cleans
The waste liquid of generation can be discharged into waste liquid buffer container 209 by cleaning device 205, then be discharged by waste liquid buffer container 209
Container 210 is contained to waste liquid.
Cleaning liquid receptacle 201 successively with power component 211, cleaning solution buffer container 202, power component 213, electromagnetism
Valve 218, reagent needle injection 207, reagent needle 206 pass through related pipe fitting and connect with pipeline formation fluid path, reagent needle cleaning dress
It sets 208 and successively contains container 210 with power component 215, waste liquid buffer container 209, power component 216, waste liquid and pass through phase
Pipe fitting is closed to connect with pipeline formation fluid path.Cleaning liquid receptacle 201 provides cleaning solution to clean to reagent needle 206, cleans
The waste liquid of generation can be discharged into waste liquid buffer container 209 by reagent needle cleaning device 208, then pass through waste liquid buffer container
209, which are discharged to waste liquid, contains container 210.
Wherein, cleaning solution needed for cleaning liquid receptacle 201 is used to hold cleaning；Cleaning liquid receptacle 201 is monitored with liquid measure
Component, liquid measure monitoring component is for the cleaning solution surplus in monitoring cleaning liquid container 201, when monitoring in cleaning liquid receptacle 201
Cleaning solution surplus deficiency when, corresponding warning information can be issued, to remind user to add cleaning solution in time；Cleaning solution buffering is held
Device 202 is used for buffer storage cleaning solution, clear in cleaning solution buffer container 202 in cleaning liquid receptacle 201 when cleaning solution deficiency
Clean liquid can continue to support the online test of a certain number of new samples；Specimen needle 203 is used for the compressing of sample；Specimen needle
Syringe 204 is quantified for sample；Specimen needle cleaning device 205 is used for the cleaning of specimen needle 203；Reagent needle 206 is for trying
The compressing of agent；Reagent needle injection 207 is quantified for reagent；Reagent needle cleaning device 208 is used for the cleaning of reagent needle 206；
Waste liquid contains the waste liquid that container 210 is generated for holding cleaning；Waste liquid contains container 210 with liquid measure monitoring component, liquid measure prison
Component is surveyed for monitoring the waste liquid liquid measure that waste liquid contains container 210, when monitoring that waste liquid contains the waste liquid liquid measure in container 210 and reach
When to the first limit value (such as waste liquid containing 210 total capacity 85%~90% of container), the prompt information of fully loaded failure is issued, with
It reminds user to replace waste liquid in time and contains container 210；Waste liquid buffer container 209 is used for buffer storage waste liquid, contains appearance in waste liquid
When waste liquid liquid measure reaches the first limit value in device 210, the cleaning solution that waste liquid buffer container 209 stores can continue to support a fixed number
Waste liquid caused by the test of sample is measured to be stored；Power component 211-216 can be for diaphragm pump or peristaltic pump etc., mainly
The power of liquid flowing in pipeline is provided；Solenoid valve 217 and 218 for realizing pipeline on-off.
The structure chart of liquid channel system according to Fig.2, obtains cleaning solution specific steps by cleaning liquid receptacle are as follows: first
Cleaning solution is injected into cleaning solution surge flask 202 from cleaning liquid receptacle 201 by power component 211, opens solenoid valve 217
And make cleaning solution surge flask 202 to the pipeline of sample needle injection 204 full of cleaning solution by power component 212, and open
Solenoid valve 218 simultaneously makes cleaning solution surge flask 202 to the pipeline of reagent needle injection 207 full of cleaning by power component 213
Liquid.
Step 102 cleans specimen needle and/or reagent needle using cleaning solution, generates waste liquid.
In this discharging of waste liquid control method, the waste liquid that can only generate in some embodiments to cleaning specimen needle is carried out
Emission control only can also carry out emission control to the waste liquid that cleaning reagent needle generates in some embodiments, certainly another
The waste liquid that can also carry out cleaning generation in some embodiments to specimen needle and reagent needle carries out emission control.
In the present embodiment, when specimen needle 203 needs to inhale sample, solenoid valve 217 is closed, sample needle injection 204 is mobile
Certain distance is to establish isolation air column, and then specimen needle 203 is moved to wait inhale in sample, inhales again by sample needle injection 204
The sample of fixed amount is taken, then specimen needle 203 is moved to and spits sample position, is spat sample to reaction cup by sample needle injection 204
It is interior, if the compressing sample operations of specimen needle are completed, need to clean specimen needle 203, it is clear that specimen needle is moved to specimen needle
Cleaning device 205 opens solenoid valve 217, and power component 212 is opened fixed duration and cleaned to specimen needle 203, cleans sample
Waste liquid caused by needle 203 is flowed into specimen needle cleaning device 205.204 working principle of reagent needle and above description specimen needle
203 it is identical, do not repeat them here.
Step 103, control waste liquid are emitted into waste liquid buffer container by pipeline.
In the present embodiment, the waste liquid that specimen needle 203 generates after being cleaned is to be flowed into specimen needle cleaning device 205
In, the waste liquid that reagent needle 204 generates after being cleaned is flowed into reagent needle cleaning device 208, and control power member is passed through
Device 214 and power component 215 are opened, and the waste liquid in specimen needle cleaning device 205 and reagent needle cleaning device 208 is passed through
Pipeline is emitted into waste liquid buffer container 209.In some embodiments, the structure of waste liquid buffer container 209 is as shown in figure 3, waste liquid
Buffer container 209 includes container cover 301 and container body 302, and container cover 301 and container body 302 are all made of cycloolefin copolymer
Object (Copolymers of Cycloolefin, COC) injection molding, the waste liquid import in container cover 301 can be single or more
It is a, it is symmetrically or non-symmetrically distributed, such as specimen needle cleaning device 205 is connect by pipeline with waste liquid import 3011, reagent needle is clear
Cleaning device 208 is connect by pipeline with waste liquid import 3012, and container body 302 is hollow cylindrical structure, and bottom is evagination
Curved surface, 302 structure of container body is not limited to cylindrical body in practical applications, has waste liquid outlet 3022 in the bottom of container body 302,
Waste liquid outlet 3022 contains container 210 with waste liquid by pipeline and connect, and the side of container body 302 can have overflow port 3021.
There is waste liquid monitoring component 303 in the inside of container body 302, the effect of waste liquid monitoring component 303 is monitoring waste liquid buffer container
Waste liquid liquid measure in 209.Waste liquid buffer container 209 can be with the waste liquid liquid measure (can be understood as allowing capacity) of buffer storage by blood
Solidifying instrument supports the maximum sample quantity of on-line testing simultaneously and waste liquid contain when container liquid measure reaches the first limit value to allow on new
The maximum sample quantity of line determines that, if coagulo meter supports that the maximum sample quantity of on-line testing simultaneously is A, waste liquid contains container
210 liquid measures allow new online maximum sample when reaching the first limit value (such as waste liquid contains container total capacity 85%~90%)
Quantity is B, then cleaning waste liquid is not spilt over after the volume that waste liquid buffer container 209 designs should ensure that completion (A+B) a test sample,
And it can there are certain safe clearances, i.e. waste liquid buffer container 209 should be greater than completing with the waste liquid liquid measure of buffer storage
(A+B) generated cleaning waste liquid after a test sample.
Step 104, discharging of waste liquid to the waste liquid for controlling waste liquid buffer container contain container.
In the present embodiment, the bottom waste stream outlet 3022 of the container body 302 of waste liquid buffer container 209 passes through pipeline and waste liquid
The connection of container 210 is contained, discharging of waste liquid to the waste liquid that power component 216 can control waste liquid buffer container 209 contains container
In 210.In one embodiment, power component 216 is waste drains pump, waste liquid buffer container 209 and waste liquid contain container 210 it
Between pipeline on be provided with waste drains pump, waste drains pump controls the discharge of the waste liquid of waste liquid buffer container 209.It can control waste drains pump to open
Setting duration is opened, so that the discharging of waste liquid of waste liquid buffer container 209 to waste liquid contains container 210.Here setting duration, can
It is determined with the permission capacity according to waste liquid buffer container 209.
In the embodiment of the present application, after specimen needle or reagent needle complete the compressing of respective sample or reagent, need by clear
Clean liquid container obtains cleaning solution, is cleaned using cleaning solution to specimen needle and/or reagent needle, generates waste liquid, first controls waste liquid
It is emitted into waste liquid buffer container, then controls discharging of waste liquid to the waste liquid of waste liquid buffer container and contains container, is held since waste liquid buffers
Device provides the buffer storage function of waste liquid, and so as to contain in waste liquid, container carries out replacement or waste liquid is removed (i.e. by waste liquid
Contain from waste liquid and cleared out in container) when, utilize the buffer storage cleaning solution specimen needle and/or reagent needle of waste liquid buffer container
The waste liquid of cleaning generation is carried out, it is just online without suspending new samples, to improve measurement efficiency and user experience.
In some embodiments, being not waste liquid buffer container contains container once there is waste liquid that will be discharged into waste liquid
, but the waste liquid of waste liquid buffer container reaches and is discharged into waste liquid again after preset threshold and contains container, it is specific as follows:
Optionally, in some embodiments of the present application, discharging of waste liquid to the waste liquid of control waste liquid buffer container contains container,
Include:
Whether the waste liquid liquid measure of monitoring waste liquid buffer container reaches preset threshold；If the waste liquid liquid measure of waste liquid buffer container reaches
To preset threshold, discharging of waste liquid to the waste liquid for controlling waste liquid buffer container contains container.
In the present embodiment, waste liquid monitoring component 303 specifically can be float level meter, in waste liquid buffer container 209
The increase of waste liquid liquid measure, the liquid level in waste liquid buffer container 209 will increase, and the float of float level meter gradually floats.
Specifically, as shown in figure 4, float level meter includes signal wire 401, float lever 402, switch 403, float 404 and float
Circlip 405 is limited, wherein the material preferably polytetrafluoroethylene of float lever 402 or polyformaldehyde (polyformaldehyde, POM)
Deng switch 403 is in the inside of float lever 402, and signal wire 401 is connect with switch 403, and float 404 is sheathed on floating
On sub bar 402, the lower end of float lever 402 is arranged in float limit circlip 405, limits to float 404, float limits circlip
405 material can be plastics.The buoyancy of waste liquid liquid measure is utilized, preset threshold is set for float 404, so that waste liquid liquid measure
When reaching preset threshold, float 404 is float state；When waste liquid liquid measure is not up to preset threshold, float 404 is sinking state.
When the waste liquid liquid measure of waste liquid buffer container reaches preset threshold, float 404 is float state, and switch 403 generates open circuit
Signal；When the waste liquid liquid measure of waste liquid buffer container is not up to preset threshold, float 404 is sinking state, and switch 403 is raw
At short-circuit signal.It should be noted that in the present embodiment, the signal that switch 403 generates in sinking state of float 404
It is open circuit signaling for short-circuit signal, float 404 signal that switch 403 generates in float state, but in practice
When switch 403 signal logic it is not limited to this.Certainly in other embodiments, waste liquid monitoring component 303 can also be
Other ways of realization, it is not limited here.
In the present embodiment, the waste liquid liquid measure of waste liquid buffer container 209 has reached preset threshold, what switch 404 generated
Signal becomes open circuit signaling from short-circuit signal, and control power component 216 opens setting duration, by waste liquid buffer container 209
Discharging of waste liquid to waste liquid contains container 210.
In the embodiment of the present application, whether the waste liquid liquid measure by monitoring waste liquid buffer container reaches preset threshold, presets threshold
Value is the buffer storage ability of the waste liquid of preset waste liquid buffer container, if the waste liquid liquid measure of waste liquid buffer container reaches
Preset threshold then needs the discharging of waste liquid for controlling waste liquid buffer container to waste liquid to contain container；If waste liquid buffer container is useless
Liquid liquid measure is not up to preset threshold, then it represents that waste liquid buffer container can also continue buffer storage waste liquid, then not needing to control
The discharging of waste liquid of waste liquid buffer container to waste liquid contains container.
In the embodiment above, if the waste liquid liquid measure that waste liquid buffer container is capable of buffer storage is preset threshold,
When waste liquid buffer container reaches preset threshold, discharging of waste liquid to the waste liquid of control waste liquid buffer container contains container, if useless
In the case that the waste liquid that liquid contains container has been expired, waste liquid buffer container will also be discharged if waste liquid contains container to waste liquid,
Waste liquid will overflow waste liquid and contain container, therefore, in order to avoid the waste liquid that waste liquid contains container overflows, reach in waste liquid buffer container
When to preset threshold, it is also necessary to the case where waste liquid contains the waste liquid liquid measure of container is considered, to decide whether that control waste liquid is slow
Discharging of waste liquid to the waste liquid for rushing container contains container, specific:
Referring to Fig. 5, discharging of waste liquid to the waste liquid of control waste liquid buffer container contains appearance in some embodiments of the present application
Device specifically comprises the following steps:
Whether step 501, the waste liquid liquid measure for monitoring waste liquid buffer container reach preset threshold.
Waste liquid can be monitored by the waste liquid monitoring component 303 (such as float level meter) in waste liquid buffer container 209
The waste liquid liquid measure of buffer container 209, the switch 403 of float level meter shown in Fig. 4 is according to the sinking and floating of float 404
State is monitoring that switch 404 is raw to judge whether the waste liquid liquid measure of waste liquid buffer container 209 reaches preset threshold
At signal open circuit signaling is become from short-circuit signal when, the waste liquid liquid measure of waste liquid buffer container 209 has reached preset threshold.
If step 502, the waste liquid liquid measure of waste liquid buffer container reach preset threshold, monitoring waste liquid contains the waste liquid liquid of container
Whether amount reaches the first limit value.
In the present embodiment, when the waste liquid liquid measure of waste liquid buffer container 209 reaches preset threshold, monitoring waste liquid contains container
Whether 210 waste liquid liquid measure reaches the first limit value, the waste liquid liquid measure of specific monitoring principle and monitoring waste liquid buffer container 209
It is identical that whether preset threshold is reached, and waste liquid contains container 210 and is also equipped with liquid inspection component, such as can be float liquid level
Meter, when the waste liquid liquid measure that waste liquid contains container 210 reaches the first limit value, float is float state, and switch generation is opened
Road signal；When the waste liquid liquid measure that waste liquid contains container 210 is not up to the first limit value, float is sinking state, switch
Generate short-circuit signal.Certainly in other embodiments, liquid inspection component can also be other ways of realization, not limit herein
It is fixed.
If the waste liquid liquid measure that step 503, waste liquid contain container is not up to the first limit value, control waste liquid buffer container gives up
Liquid is emitted into waste liquid and contains container.
In the present embodiment, if switch 403 generates short-circuit signal, indicate that float 404 is in sinking state, waste liquid dress
The waste liquid liquid measure for containing container 210 is not up to the first limit value, and the discharging of waste liquid of waste liquid buffer container 209 to waste liquid contains appearance at this time
It is that not will lead to waste liquid and contain the waste liquid of container 210 to overflow after device 210.Therefore control power component 216, which can be opened, sets
Timing is long, and the discharging of waste liquid of waste liquid buffer container 209 to waste liquid is contained container 210.
If the waste liquid liquid measure that step 504, waste liquid contain container reaches the first limit value, newly generated waste liquid is stored in useless
Liquid buffer container forbids newly generated discharging of waste liquid to waste liquid to contain container, and issues the prompt information of fully loaded failure, such as can
To sound an alarm, audible alarm or light warning can be.
In the present embodiment, if switch 403 generates open circuit signaling, indicate that float 404 is in float state, waste liquid dress
The waste liquid liquid measure for containing container 210 reaches the first limit value, and the discharging of waste liquid of waste liquid buffer container 209 to waste liquid contains container at this time
After 210, the waste liquid spilling that waste liquid contains container 210 may result in.Therefore control power component 216 is not turned on, and will newly be produced
Raw waste liquid is stored in waste liquid buffer container 209, and newly generated waste liquid is when monitoring that waste liquid contains the waste liquid liquid measure of container and reach
To after the first limit value, waste liquid caused by specimen needle and/or reagent needle is cleaned, forbids newly generated discharging of waste liquid to waste liquid
Container 210 is contained, and issues the prompt information of fully loaded failure, the prompt information of fully loaded failure refers to for prompting the user with waste liquid
Contain the fully loaded prompt information of container.
In the embodiment of the present application, is not overflowed to guarantee that waste liquid contains the waste liquid of container, need to monitor waste liquid and contain appearance
Whether the waste liquid liquid measure of device reaches the first limit value, if the waste liquid liquid measure that waste liquid contains container is not up to the first limit value, table
Show that waste liquid contains container and can also contain waste liquid, discharging of waste liquid to the waste liquid that can control waste liquid buffer container contains container；Such as
The waste liquid liquid measure that fruit waste liquid contains container reaches the first limit value, indicates that waste liquid contains container and cannot be further continued for containing waste liquid,
It needs newly generated waste liquid being stored in waste liquid buffer container, forbids newly generated discharging of waste liquid to waste liquid to contain container, concurrently
It has the prompt information of fully loaded failure, so that the waste liquid for prompting user more to renew contains container or cleaning waste liquid contains in container
Waste liquid.
Referring to Fig. 6, after the prompt information for issuing fully loaded failure, the application's is useless in some embodiments of the present application
Liquid discharge control method further include:
Step 601, when monitoring that waste liquid contains the waste liquid liquid measure of container and reaches the first limit value, to online new samples
It is counted, allowing to set quantity, (it is newly online most that i.e. above-mentioned waste liquid contains permission when container liquid measure reaches the first limit value
Large sample quantity B) new samples it is online.Described here is online, refers to and carries out online test to new samples.
Step 602, when online new samples quantity reaches setting quantity, monitor whether fully loaded failure is eliminated.
If step 603, fully loaded failure are not eliminated, suspend the online of new samples.
If step 604, fully loaded Failure elimination, allow the online of new samples.
In the embodiment of the present application, after the waste liquid liquid measure that waste liquid contains container 210 reaches the first limit value, waste liquid is contained
Container 210 is to carry out fully loaded Failure elimination, and eliminate new sample during being fully loaded with failure to guarantee that waste liquid contains container 210
The online of this is not interrupted, it is necessary to the buffer storage of waste liquid is carried out using waste liquid buffer container 209.Permission can be preset
The online setting quantity of new samples, i.e., waste liquid described above, which contains when 210 liquid measure of container reaches the first limit value, to be allowed on new
The maximum sample quantity of line is B, such as B=10.Online new samples are counted, when counting on online new samples quantity
When reaching setting quantity 10, whether the fully loaded failure that monitoring waste liquid contains container 210 at this time is eliminated, if fully loaded failure is also
It does not eliminate, if newly generated waste liquid will make the waste liquid liquid measure of waste liquid buffer container 209 then new samples continuation is online
It will be more than the permission capacity of waste liquid buffer container 209, will lead to waste liquid spilling, it is therefore necessary to suspend the online of new samples, directly
To fully loaded Failure elimination；If fully loaded Failure elimination, the waste liquid of waste liquid buffer container 209 is can be discharged into waste liquid dress
Container 210 is contained, without having to worry about waste liquid liquid measure is more than the permission capacity of waste liquid buffer container 209, therefore allows the upper of new samples
Line.
In the present embodiment, it can monitor whether fully loaded failure is eliminated by following three kinds of modes, specific:
(1), optional, in some embodiments of the present application, monitor whether fully loaded failure is eliminated, comprising:
Monitoring waste liquid, which contains container and whether is changed to new waste liquid, contains container.
If waste liquid contains container when being changed to new waste liquid and containing container, it is judged as fully loaded Failure elimination.
In the embodiment of the present application, in the specific implementation, it can identify that waste liquid contains container by way of hardware or software
Whether replace.For example, a switch, which can be set, triggers the switch when waste liquid, which contains container, to be replaced.In another example can be with
As soon as containing container 210 for each waste liquid is arranged a unique identification, the mark that container 210 is contained by monitoring waste liquid be can know that
Waste liquid, which contains container and whether is changed to new waste liquid, contains container, if monitor that waste liquid contains the mark of container 210 and changes, gives up
Liquid, which contains container 210 and is changed to new waste liquid, contains container, at this point, judging fully loaded Failure elimination；If monitoring that waste liquid contains
When the mark of container 210 does not change, indicate that waste liquid contains container 210 and do not replace, fully loaded failure is not eliminated.Here only
One mark can be bar code or two dimensional code, and the relevant information of container is contained by scanning the available waste liquid of the unique identification.
Scanning can be automatically scanning or either scans, and in some embodiments, when replacement waste liquid contains container, either scans newly give up
Liquid contains the unique identification of container, and coagulo meter can recognize that waste liquid contains container and is replaced, and new waste liquid is contained container only
Memory is arrived in one mark storage.
(2), optional, in some embodiments of the present application, monitor whether fully loaded failure is eliminated, comprising:
If waste liquid contains container when being changed to new waste liquid and containing container, monitor new waste liquid contain container waste liquid liquid measure whether
Lower than the second limit value.
If new waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that fully loaded failure is not eliminated.
If new waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as fully loaded Failure elimination.
In the embodiment of the present application, it is changed to new waste liquid if waste liquid contains container 210 and contains container, it is new due to not can guarantee
Waste liquid contains whether container can also contain waste liquid, therefore also needs to monitor new waste liquid and contain the waste liquid liquid measure of container whether be lower than
Two limit values, specifically can be real by the way that the liquid inspection component (such as float level meter) that new waste liquid contains in container is arranged in
It is existing, if new waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that fully loaded failure is not eliminated；If new useless
Liquid contains the waste liquid liquid measure of container lower than the second limit value, is judged as fully loaded Failure elimination.
(3), optional, in some embodiments of the present application, monitor whether fully loaded failure is eliminated, comprising:
Whether the liquid measure that monitoring waste liquid contains container is lower than the second limit value.
If waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that fully loaded failure is not eliminated.
If waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as fully loaded Failure elimination.
In the embodiment of the present application, in addition in above (1) and (2) embodiment, by the way of more renewing waste liquid and containing container
Except, fully loaded failure can be removed in such a way that the waste liquid contained in container 210 to waste liquid is cleared up.When containing appearance to waste liquid
When device 210 carries out waste liquid removing, if monitoring, waste liquid contains the waste liquid liquid measure of container 210 lower than the second limit value, is judged as
Fully loaded Failure elimination, wherein the value size of the second limit value can be identical with the first limit value.For example, float liquid can be passed through
Position meter monitoring waste liquid contains the liquid measure of container and whether is lower than the second limit value, if the float 404 of float level meter is from floating shape
State becomes sinking state, when the signal for monitoring that switch 403 generates becomes short-circuit signal from open circuit signaling, indicates waste liquid dress
The waste liquid liquid measure for containing container 210 is lower than the second limit value, i.e., the waste liquid that waste liquid contains container 210 is removed a part or complete
Portion is judged as fully loaded Failure elimination；If the float 404 of float level meter is still float state, switch 403 is monitored
When generating open circuit signaling, indicate that waste liquid contains the waste liquid liquid measure of container 210 not less than the second limit value, i.e. waste liquid contains container
210 waste liquid is not removed, is judged as that fully loaded failure is not eliminated.
The second limit value in embodiment, can be identical as the first above-mentioned limit value.When the first limit value and second limit
When definite value difference, float level meter needs have the function of detecting two liquid levels, such as can have two and be arranged not
Level switch.
Based on each embodiment described above, if liquid measure monitoring component or power component 216 are abnormal, waste liquid
The waste liquid of buffer container 209 is unable to normal discharge and contains container 210 to waste liquid.Such as the float liquid in waste liquid buffer container 209
When 403 exception of switch namely the either sinking state of float 404 and float state of position meter, what switch 404 generated
Signal is all short-circuit signal, and power component 216 will not be opened always, but actually, it is possible to waste liquid buffer container 209
Waste liquid liquid measure already exceed preset threshold, power component 216 is not turned on, and discharging of waste liquid to waste liquid can not be contained container
210, cause waste liquid to enter the pipeline of front by waste liquid import 3011 and/or waste liquid import 3012, so as to cause parts damages
Or biological pollution.In order to guarantee the problem of not leading to parts damages or biological pollution, as shown in Figures 2 and 3, the one of the application
In a little embodiments, waste liquid buffer container 209 is additionally provided with overflow port 3021, when the waste liquid of waste liquid buffer container 209 cannot be discharged into
When waste liquid contains container 210, then for the liquid level of waste liquid when being higher than overflow port 3021, waste liquid can be from waste liquid buffer container 209
Overflow port 3021 flows out.
Overflow port 3021 can contain container 210 by piping connection waste liquid, and/or spare waste liquid contain container, and/or
The waste liquid of spare waste liquid buffer container and/or waste liquid pool, waste liquid buffer container 209 is emitted into waste liquid dress from the outflow of overflow port 3021
It contains container 210, and/or spare waste liquid contains container, and/or spare waste liquid buffer container and/or waste liquid pool.
In the embodiment of the present application, when the waste liquid of waste liquid buffer container 209 cannot be discharged into waste liquid and contain container 210, it is
The problem of guaranteeing not generation part damage or biological pollution, is provided with overflow port 3021, when useless on waste liquid buffer container 209
When the liquid level of liquid rises to overflow port 3021, waste liquid can be discharged by overflow port 3021, specific overflow protection scheme includes
It is several below:
As shown in fig. 7, passing through specimen needle pipeline 701 for the discharging of waste liquid of cleaning specimen needle generation to waste liquid buffer container
209, the discharging of waste liquid for being generated cleaning reagent needle by reagent needle tubing road 702 holds to waste liquid buffer container 209 when waste liquid buffers
When the float level meter of device 209 breaks down, power component 216 will not be opened, and cannot will be given up by waste liquid outlet 3022
Liquid is emitted into waste liquid and contains container 210, and when the waste liquid liquid measure inside waste liquid buffer container 209 reaches certain value, liquid level will
More than overflow port 3021.Overflow port 3021 is linked into waste liquid by pipeline and contains container 210, when waste liquid liquid level is more than overflow port
When 3021, waste liquid is emitted into waste liquid by overflow port 3021 and contains in container 210, it should be noted that in power component 216
And waste liquid contains and is also provided with dismountable active joint 703 between container 210, and waste liquid is facilitated to contain container 210 more
It changes.
As shown in figure 8, power component 216 will not when the float level meter of waste liquid buffer container 209 breaks down
It opens, discharging of waste liquid to waste liquid cannot be contained into container 210 by waste liquid outlet 3022, inside waste liquid buffer container 209
When waste liquid liquid measure reaches certain value, liquid level will be more than overflow port 3021.Overflow port 3021 is linked into spare waste liquid by pipeline
Container 804 is contained, when waste liquid liquid level is more than overflow port 3021, waste liquid is emitted into spare waste liquid by overflow port 3021 and contains appearance
In device 804.Liquid measure monitoring component, such as float liquid level can be set it should be noted that spare waste liquid contains container 804 also
Meter issues police when monitoring that spare waste liquid contains the waste liquid liquid measure of container 804 more than preset threshold by float level meter
Accuse information.
As shown in figure 9, power component 216 will not when the float level meter of waste liquid buffer container 209 breaks down
It opens, discharging of waste liquid to waste liquid cannot be contained into container 210 by waste liquid outlet 3022, inside waste liquid buffer container 209
When waste liquid liquid measure reaches certain value, liquid level will be more than overflow port 3021, and overflow port 3021 is linked into spare waste liquid by pipeline
Buffer container 904, when waste liquid liquid level is more than overflow port 3021, waste liquid, which is emitted into spare waste liquid buffering by overflow port 3021, to be held
Device 904.It should be noted that liquid measure monitoring component, such as float liquid level has also can be set in spare waste liquid buffer container 904
Meter issues police when monitoring the waste liquid liquid measure of spare waste liquid buffer container 904 more than preset threshold by float level meter
Accuse information.
As shown in Figure 10, in order to save exploitation and production cost, spare waste liquid buffer container 1004 can use and waste liquid
The waste liquid outlet needs of the identical material of buffer container 209, spare waste liquid buffer container 1004 seal, such as close with glue or plug
It seals.
As shown in figure 11, overflow port 3021 can also be linked into waste liquid pool 1104 by pipeline, when waste liquid buffer container 209
Waste liquid liquid level be more than overflow port 3021 when, waste liquid is emitted into waste liquid pool 1104 by overflow port 3021.
The application also provides the coaglation analyzer (abbreviation coagulo meter) of an embodiment, be used for optical detecting and analyze with
The related predetermined substance quantity of blood clotting/fibrinolytic function and its level of activity, sample are blood plasma.The blood clotting of present embodiment point
Analyzer Clotting-time method, Chromogenic assay and immunoturbidimetry carry out optical detecting to sample.It is coagulated used in present embodiment
Gu Time Method is a kind of using sample process of setting as the measuring method of the variation detection of transmitted light.Measurement item has PT (blood coagulation
Zymogen time), APTT (thromboplastin time), TT (thrombin time) and FIB (fibrin commercial weight) etc..Chromogenic assay
Measurement item has AT- III (antithrombin Ⅲ) etc., and the measurement item of immunoturbidimetry has d-dimer (D-Dimer) and FDP etc..
The coaglation analyzer includes: at least one reaction vessel, for providing reacting environment for sample and reagent；Blood coagulation inspection
Device is surveyed, for carrying out hemostasis examination to through reagent treated sample, obtains the electrical signal information of reflection solidification situation；Processing
Device, for receiving and processing the electrical signal information of the hemostasis detestion device output, to obtain the measurement parameter of sample；Wherein,
The processor is also used to execute the discharging of waste liquid control method according to any of the above-described embodiment.
It should be understood that magnitude of the sequence numbers of the above procedures are not meant to execute suitable in the various embodiments of the application
Sequence it is successive, the execution of each process sequence should be determined by its function and internal logic, the implementation without coping with the embodiment of the present application
Process constitutes any restriction.
The above, above embodiments are only to illustrate the technical solution of the application, rather than its limitations；Although referring to before
Embodiment is stated the application is described in detail, those skilled in the art should understand that: it still can be to preceding
Technical solution documented by each embodiment is stated to modify or equivalent replacement of some of the technical features；And these
It modifies or replaces, the range of each embodiment technical solution of the application that it does not separate the essence of the corresponding technical solution.
Claims (14)
1. a kind of discharging of waste liquid control method, which is characterized in that be applied to coagulo meter, the coagulo meter include cleaning liquid receptacle,
Specimen needle and/or reagent needle, waste liquid buffer container and waste liquid contain container, which comprises
Cleaning solution is obtained by the cleaning liquid receptacle；
The specimen needle and/or reagent needle are cleaned using the cleaning solution, generate waste liquid；
It controls the waste liquid and the waste liquid buffer container is emitted by pipeline；
Discharging of waste liquid to the waste liquid for controlling the waste liquid buffer container contains container.
2. the method according to claim 1, wherein the discharging of waste liquid of the control waste liquid buffer container is extremely
The waste liquid contains container, comprising:
Whether the waste liquid liquid measure for monitoring the waste liquid buffer container reaches preset threshold；
If the waste liquid liquid measure of the waste liquid buffer container reaches preset threshold, the discharging of waste liquid of the waste liquid buffer container is controlled extremely
The waste liquid contains container.
3. the method according to claim 1, wherein the discharging of waste liquid of the control waste liquid buffer container is extremely
The waste liquid contains container, comprising:
Whether the waste liquid liquid measure for monitoring the waste liquid buffer container reaches preset threshold；
If the waste liquid liquid measure of the waste liquid buffer container reaches preset threshold, monitoring the waste liquid and containing the waste liquid liquid measure of container is
It is no to reach the first limit value；
If the waste liquid liquid measure that the waste liquid contains container is not up to the first limit value, the waste liquid row of the waste liquid buffer container is controlled
It puts to the waste liquid and contains container.
4. method according to any one of claim 1-3, which is characterized in that the waste liquid buffer container and the waste liquid
It contains and is provided with waste drains pump on the pipeline between container, the waste drains pump controls the discharge of the waste liquid of the waste liquid buffer container.
5. according to the method described in claim 4, it is characterized in that, the discharging of waste liquid of the control waste liquid buffer container extremely
The waste liquid contains container, comprising:
It controls the waste drains pump and opens setting duration, so that the discharging of waste liquid of the waste liquid buffer container to the waste liquid contains
Container.
6. according to the method described in claim 3, it is characterized in that, the method also includes:
If the waste liquid liquid measure that the waste liquid contains container reaches the first limit value, newly generated waste liquid is stored in the waste liquid and is delayed
Container is rushed, the newly generated discharging of waste liquid to the waste liquid is forbidden to contain container, and issues the prompt information of fully loaded failure.
7. according to the method described in claim 6, it is characterized in that, also being wrapped after the prompt information for issuing fully loaded failure
It includes:
When online new samples quantity reaches setting quantity, monitor whether the fully loaded failure is eliminated；
If the fully loaded failure is not eliminated, suspend the online of new samples；
If the fully loaded failure has been eliminated, allow the online of new samples.
8. the method according to the description of claim 7 is characterized in that whether the monitoring fully loaded failure is eliminated, comprising:
It monitors the waste liquid and contains container and whether be changed to new waste liquid and contain container；
If the waste liquid contains container when being changed to new waste liquid and containing container, it is judged as the fully loaded Failure elimination.
9. the method according to the description of claim 7 is characterized in that whether the monitoring fully loaded failure is eliminated, comprising:
If the waste liquid contains container when being changed to new waste liquid and containing container, the waste liquid liquid measure that the new waste liquid contains container is monitored
Whether the second limit value is lower than；
If the new waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that the fully loaded failure is not eliminated；
If the new waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as the fully loaded Failure elimination.
10. the method according to the description of claim 7 is characterized in that whether the monitoring fully loaded failure is eliminated, comprising:
It monitors the waste liquid and contains the liquid measure of container and whether be lower than the second limit value；
If the waste liquid contains the waste liquid liquid measure of container not less than the second limit value, it is judged as that the fully loaded failure is not eliminated；
If the waste liquid contains the waste liquid liquid measure of container lower than the second limit value, it is judged as the fully loaded Failure elimination.
11. according to the method described in claim 3, it is characterized in that, the method also includes:
When monitoring that the waste liquid contains the waste liquid liquid measure of container and reaches the first limit value, online new samples are counted
Number, the new samples for allowing to set quantity are online.
12. method described in any one of -11 according to claim 1, which is characterized in that the waste liquid buffer container is equipped with overflow
Mouthful, the method also includes:
When the waste liquid of the waste liquid buffer container, which cannot be discharged into the waste liquid from the waste liquid buffer container, contains container, then
When the liquid level of waste liquid in the waste liquid buffer container is when being higher than the overflow port, waste liquid is flowed out from the overflow port.
13. according to the method for claim 12, which is characterized in that the overflow port is contained by waste liquid described in piping connection
Container, and/or spare waste liquid contain container, and/or spare waste liquid buffer container and/or waste liquid pool, the method also includes:
The waste liquid of the waste liquid buffer container is emitted into the waste liquid from overflow port outflow and contains container, and/or described standby
Container, and/or the spare waste liquid buffer container and/or the waste liquid pool are contained with waste liquid.
14. a kind of coaglation analyzer characterized by comprising
At least one reaction vessel, for providing reacting environment for sample and reagent；
Hemostasis detestion device obtains the telecommunications of reflection solidification situation for carrying out hemostasis examination to through reagent treated sample
Number information；
Processor, for receiving and processing the electrical signal information of the hemostasis detestion device output, to obtain the measurement ginseng of sample
Number；
Wherein, the processor is also used to execute -13 described in any item discharging of waste liquid control methods according to claim 1.
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Cited By (1)
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| CN114778814A (en) * | 2022-06-13 | 2022-07-22 | 深圳市帝迈生物技术有限公司 | Waste liquid discharge system, sample analyzer and waste liquid discharge method |
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