CN109260185A - A kind of drug for the treatment of cancer - Google Patents
A kind of drug for the treatment of cancer Download PDFInfo
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- CN109260185A CN109260185A CN201811119867.3A CN201811119867A CN109260185A CN 109260185 A CN109260185 A CN 109260185A CN 201811119867 A CN201811119867 A CN 201811119867A CN 109260185 A CN109260185 A CN 109260185A
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- drug
- cancer
- treatment
- basic fuchsin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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Abstract
The purpose of the present invention is to provide a kind of drugs for the treatment of cancer, it is characterised in that: the drug is using basic fuchsin as active constituent.Intracorporal acidic environment can be restored to normal slight alkali environment by the drug, to activate powerful immune function, be can be used for preparing the drug of inhibition and/or treating cancer, be particularly suitable for lung cancer, gastric cancer and intestinal cancer.And the drug is nontoxic, without side-effects, the liver kidney and each organ function of patient are normal after treatment, and treatment is convenient, and cheap, quick, materials are convenient, are conducive to promote and apply.
Description
Technical field
The invention belongs to pharmaceutical technology fields, specifically provide a kind of drug for the treatment of cancer.
Background technique
Increasingly to aggravate when front ring pollutes unexpectedly, living environment constantly deteriorates that contact the mankind with carcinogenic factor more and more closer,
Cancer patient is caused to be increasing.
Gastric cancer, liver cancer, lung cancer, breast cancer, spleen cancer, prostate cancer, cutaneum carcinoma etc. type have more than 250 kinds enough, Wo Menren
The all possible canceration in any position of body, causes the death rate of cancer to be continuously increased.
Cancer is not the external germ for invading human body and the lesion generated, is all physics, the chemistry of human habitat
Caused by destroying anti-cancer system (immune system) with biological factor, intracorporal normal cell variation is made to produce cancer cell, people
Body is to be inhibited by immune system and eliminate cancer cell, if the immune system of human body is destroyed, weakens anti-cancer ability, gives cancer
Cell causes strong variation condition, and cancer cell can be made to continue proliferation and form visible cancer block.
The cause of disease of cancer:
Human body is by a variety of different cell compositions, and human normal cell is to like meta-alkalescence food, that is, light
Vegetarian diet, and wilfully give the soma of oneself to supply salty peppery acidic food (such as animal flesh) as the owner of cell, breathe
The air of pollution makes cell by very big oppressive and torment, and this state for time is long, and cell is in order to survive down, i.e.,
Become the cell that can be survived in abnormal environment, the mutant to survive in this case is exactly cancer
Cell.
Its feature is: 1. not dead, the Immortalization in the environment oneself liked.2. it aims at itself and lives, here it is cancers
The characteristics of cell.Cancer cell does not abide by any order indicated by the life entity, and the breeding that cancer cell is done at will is constantly sent out
Exhibition, it needs to obtain the supply of vascular nutrition element, so the gene of cancer cell spray so-called blood to closest blood vessel
Pipe generates substance, and such blood vessel stretches out sprig, stretches towards the direction for spraying angiogenesis substance, then blood vessel and cancer cell phase
Even, cancer cell has just obtained the supply of nutrient, and constantly division growth gradually grows up as mass.
The difference of cancer cell and normal cell is that cancer cell is complete egoism, and normal human body cell does not have
One cell is for oneself work.Such as thyroid cell, it lives, is not thyroid gland itself, but for the work of liver kidney
Property, the role of thyroid hormone is produced when one.For another example pancreas islet generates insulin and is not configured to pancreas islet itself, but in order to divide
The energy of solution sugar supply whole body.Only cancer cell is selfish, living of pushing way by shoving or bumping.
The living environment of cancer cell is not removed in a word, cancer can not just be removed.Cancer is a kind of genopathy, because body is exempted from
Epidemic disease system damage when inability repairs impaired gene, makes the cancer cell of gene denaturation and formation.At this moment our body is with regard to beam
Is hand without plan? no, our body, which has powerful immune system completely, can remove and repair the cell of variation, what is used
Method? it seeks to restore the pH value of normal cell body fluid, while also destroying the acidic environment that cancer cell is liked.We
The pH value of human normal is between 7.35-7.45.
When canceration occurs for human body, intracorporal pH value is environment acid, that acidity exactly cancer cell is liked.In order to help
Body beat cancer is helped, so that powerful immune system is restored function, we will restore the pH value of body fluid, normal cell is made to return to him
In the slight alkali environment liked.Immune organ immunocyte and immune molecule will restore powerful immune function, to attack
Cancer cell is killed, this is uniquely not injure normal cell, only kills the treatment method of cancer cell.
Basic fuchsin is strongest core dyestuff, can make viscous protein elastic fibrous tissue and fuchsinophile granules stain, nervous centralis
Nuclear staining agent, bacteriology prepare Schiff's reagent in analytical chemistry and examine aldehydes, use bromate titration for identifying tubercle bacillus
Oxidation-reduction indicator be also used for manufacture color lake for contaminating cotton, fiber crops, staple fibre straw, leather feather, fat etc..Its
Chemical structural formula are as follows:
Molecular formula and molecular weight
Formula 1:C20H20N3CL=337.84
Formula 2:C19H18N3CL=323.82
Character: for the crystallization of green metal gloss, being dissolved in ethyl alcohol and amylalcohol, be slightly soluble in water, take on a red color in aqueous solution, insoluble
In ether.
Summary of the invention
The purpose of the present invention is to provide a kind of drug for the treatment of cancer, which can restore intracorporal acidic environment
To normal slight alkali environment, to activate powerful immune function, thus inhibition and/or treating cancer.
Technical solution of the present invention is as follows:
A kind of drug for the treatment of cancer, it is characterised in that: the drug is using basic fuchsin as active constituent.
The drug for the treatment of cancer of the present invention, it is characterised in that: it is pharmaceutically acceptable that the drug contains basic fuchsin
Auxiliary material or complementary ingredient, the pharmaceutically acceptable auxiliary material or complementary ingredient are preferably medical starch, preferred matter
Measure portion rate are as follows: basic fuchsin 25-85, medical starch 35-75.
The drug for the treatment of cancer of the present invention, it is characterised in that: the drug is oral preparation, ejection preparation or bolt
Agent, such as tablet, oral solution, capsule, injection, electuary or suppository.
It has been investigated that basic fuchsin can be used for preparing the drug of inhibition and/or treating cancer, it is particularly suitable for lung
Cancer, gastric cancer and intestinal cancer.
When patient takes basic fuchsin, trend that the pH value of body fluid (urine of discharge) is increased significantly.And make cancer
The acidic constitution of patient is restored to alkalescent constitution, is conducive to the immunity for enhancing human body, and cancer cell is made to be suppressed or remove,
To make intracorporal cancer cell disappear.The variation of patient's urine ph values is shown in Table 1 and Fig. 1 after medication:
Variation of patient's (vegetarian diet) in different time urine ph values after table 1 is taken medicine
Note: urine ph values peak for 2-3 hours after the tablet has been ingested, and peak period is 3-4 hours sustainable, and after the tablet has been ingested
It is restored within 5-6 hours or more substance liquid pH value.
Urine: basic fuchsin was excreted into (table 1) in about 4-6 hours.
Just: excreting and (visually observe) within about 12-24 hours.
The invention has the following beneficial effects:
1. nontoxic, without side-effects, the liver kidney and each organ function of patient are normal after treatment.
2. it is quick, by Humoral immunity to optimum state within 1~2 hour.
3. materials are convenient, be conducive to promote.
4. it is cheap, it reduces the heavy burdens to country and individual.
5. the patient after curing puts on weight quickly.
6. treatment is convenient, take orally, without being hospitalized.
7. drug does not retain in vivo, can be excreted after 24 hours.
Detailed description of the invention
Patient's urine ph values change over time curve after Fig. 1 medication.
Specific embodiment
Basic fuchsin used in the present embodiment is purchased from Tianjin Ju Hua Chemical Co., Ltd..
Embodiment 1
Basic fuchsin virulence experiment:
Material: albino guinea-pig totally 24, Shenyang Pharmaceutical University, conventinal breeding are purchased from；
Basic fuchsin, Tianjin Ju Hua Chemical Co., Ltd..
The proportion of experimental animal is grouped: experiment being randomly divided into 4 groups (every group 6, half male and half female) with cavy, respectively
The high, medium and low dosage group of blank control group, basic fuchsin.
Medication: every cavy daily is administered once the set time in the morning, high, medium and low three dosage groups of basic fuchsin
Dosage is respectively 8mg/kg weight/d, 6mg/kg weight/d, 4mg/kg weight/d；Administration time is 21 days, observes 3 daily
It~4 times, observes cavy spirit, appetite, coat glossiness, physical state, alertness and hides the abilities such as capture.After 21 days
Have no any variation.
Embodiment 2
After taking basic fuchsin, by observing the case where basic fuchsin passes through blood in different times, it can see
Basic fuchsin is absorbed into blood with the state dissolved out.And the process by entering blood cell, the pH value of blood can be improved,
The acidic environment that cancer cell is liked is destroyed, the environment of meta-alkalescence is become, creates best ring to normal cell growth
Border, while the immune system for promoting body powerful plays one's part to the full, and generates T- lymphocytotoxin and kills cancer cell, reaches
To the purpose of healing.
Blood picture observation:
One, object is observed:
1. healthy experiencer does normal population observation object.
2. the volunteer that fully recovers in patient does experimental subjects.
Two, instrument:
Binocular biological microscope XSP-12G type
Manufacturer: river light Instrument Factory
Three, reagent:
1, Rui Shi-Ji's nurse Sa Albert'stain Albert liquid (commercially available)
2, phosphate buffer (commercially available)
Four, operating method:
1. healthy premenopausal volunteers peripheral blood is taken to recommend (normal control Blood piece, spare)
2. after taking volunteer to take orally basic fuchsin the peripheral blood push jack of different time (oral basic fuchsin Blood piece, it is standby
With).
3. after the completion of last time is taken a blood sample, oral basic fuchsin Blood piece dyes together with normal control Blood piece, standby wait do
With.
Five, oral basic fuchsin is observed in expanding 100 times of object lens (oil mirror) and the ocular microscopes of 12.5 times of expansion
Blood piece, it is in kind to check in the state of expanding 1250 times, it the results are shown in Table 2.
Table 2 observes result
Observe result:
1. after taking basic fuchsin, entering blood through absorption of human body, each tissue of whole body and cell are entered by blood circulation
It is inside and outside.A few hours are retained, the pH value that body fluid is changed into meta-alkalescence from acid pH value can be sufficiently adjusted, meet normal cell
Growing environment, so that immune system is restored its powerful immune function, to eliminate cancer cell.
2, for haemocyte after 4~6 hours are dyed, dyestuff overflows cell after retaining 2~4 hours into the cell
Outside, but in body fluid it still retains, body fluid slight alkali environment can be kept up to 10 hours or so in this way.
Embodiment 3
Basic fuchsin treats lung cancer:
That select herein is all invalid patient after treatment is made a definite diagnosis by hospital more than area, there is some patientss transfer,
Through multi-treatment, pain does not subtract, and liver kidney severe is impaired, and some patients have liied in bed, and take pain relief after drug of the present invention
Appetite increases, and symptom improves after one month, and symptom disappears after three months.
Patient dosage: capsule 300mg/ (wherein basic fuchsin 150mg, medical starch 150mg)；Everyone oral 1~
2/day.
Instructions of taking: early basic fuchsin capsule bfore meals, patient medical record are shown in Table 3 daily.
3 patients with lung cancer individual's patient chart of table
Embodiment 4
Basic fuchsin treats gastric cancer:
That select herein is all invalid patient after treatment is made a definite diagnosis by hospital more than area, there is some patientss transfer,
Through multi-treatment, pain does not subtract, and liver kidney severe is impaired, and some patients have liied in bed, and take pain relief after drug of the present invention
Appetite increases, and symptom improves after one month, and symptom disappears after three months.
Patient dosage: capsule 300mg/ (wherein basic fuchsin 150mg, medical starch 150mg)；Everyone oral 1~
2/day.
Instructions of taking: early basic fuchsin capsule bfore meals, patient medical record are shown in Table 4 daily.
4 patients with gastric cancer individual medical record of table
Embodiment 5
Basic fuchsin treats intestinal cancer:
That select herein is all invalid patient after treatment is made a definite diagnosis by hospital more than area, there is some patientss transfer,
Through multi-treatment, pain does not subtract, and liver kidney severe is impaired, and some patients have liied in bed, and take pain relief after drug of the present invention
Appetite increases, and symptom improves after one month, and symptom disappears after three months.
Patient dosage: capsule 300mg/ (wherein basic fuchsin 150mg, medical starch 150mg)；Everyone oral 1~
2/day.
Instructions of taking: early basic fuchsin capsule bfore meals, patient medical record are shown in Table 5 daily.
5 patients with bowel cancer medical history sheet of table
The above embodiments merely illustrate the technical concept and features of the present invention, and its object is to allow be familiar with technique
Personage cans understand the content of the present invention and implement it accordingly, and it is not intended to limit the scope of the present invention.It is all according to this hair
Equivalent change or modification made by bright Spirit Essence, should be covered by the protection scope of the present invention.
Claims (10)
1. a kind of drug for the treatment of cancer, it is characterised in that: the drug is using basic fuchsin as active constituent.
2. according to the drug for the treatment of cancer described in claim 1, it is characterised in that: the drug, which contains basic fuchsin, can pharmaceutically connect
The auxiliary material or complementary ingredient received.
3. according to the drug for the treatment of cancer described in claim 1, it is characterised in that: the pharmaceutically acceptable auxiliary material or auxiliary
Property ingredient be medical starch.
4. according to the drug for the treatment of cancer described in claim 3, it is characterised in that: the drug is consisting of mass parts ratio:
Basic fuchsin 25-85, medical starch 35-75.
5. according to the drug of any treating cancer of Claims 1 to 4, it is characterised in that: the drug is oral preparation, note
Penetrate preparation or suppository.
6. according to the drug for the treatment of cancer described in claim 5, it is characterised in that: the drug is tablet, oral solution, capsule
Agent, injection, electuary or suppository.
7. purposes of the basic fuchsin in the drug of preparation inhibition and/or treating cancer.
8. purposes according to claim 7, it is characterised in that: basic fuchsin is used to prepare inhibition and/or treats lung cancer
Drug.
9. purposes according to claim 7, it is characterised in that: basic fuchsin is used to prepare inhibition and/or treats gastric cancer
Drug.
10. purposes according to claim 7, it is characterised in that: basic fuchsin is used to prepare inhibition and/or treats intestinal cancer
Drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811119867.3A CN109260185A (en) | 2018-09-25 | 2018-09-25 | A kind of drug for the treatment of cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811119867.3A CN109260185A (en) | 2018-09-25 | 2018-09-25 | A kind of drug for the treatment of cancer |
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| Publication Number | Publication Date |
|---|---|
| CN109260185A true CN109260185A (en) | 2019-01-25 |
Family
ID=65198365
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811119867.3A Withdrawn CN109260185A (en) | 2018-09-25 | 2018-09-25 | A kind of drug for the treatment of cancer |
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| Country | Link |
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| CN (1) | CN109260185A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494351A (en) * | 2020-04-09 | 2020-08-07 | 齐齐哈尔医学院 | Application of basic fuchsin in antitumor and medicine |
-
2018
- 2018-09-25 CN CN201811119867.3A patent/CN109260185A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494351A (en) * | 2020-04-09 | 2020-08-07 | 齐齐哈尔医学院 | Application of basic fuchsin in antitumor and medicine |
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| PB01 | Publication | ||
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| WW01 | Invention patent application withdrawn after publication | ||
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Application publication date: 20190125 |