CN109254020B - From microscopic CT image spatial resolution die body of taking positioner - Google Patents
From microscopic CT image spatial resolution die body of taking positioner Download PDFInfo
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- CN109254020B CN109254020B CN201811394680.4A CN201811394680A CN109254020B CN 109254020 B CN109254020 B CN 109254020B CN 201811394680 A CN201811394680 A CN 201811394680A CN 109254020 B CN109254020 B CN 109254020B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
- G01N23/02—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material
- G01N23/04—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material
- G01N23/046—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2223/00—Investigating materials by wave or particle radiation
- G01N2223/03—Investigating materials by wave or particle radiation by transmission
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2223/00—Investigating materials by wave or particle radiation
- G01N2223/10—Different kinds of radiation or particles
- G01N2223/101—Different kinds of radiation or particles electromagnetic radiation
- G01N2223/1016—X-ray
Abstract
The invention discloses a micro CT image spatial resolution die body with a positioning device, which comprises a first fixing seat, a second fixing seat, a positioning pin and a first spatial resolution module; the upper end of the first semi-cylinder is provided with a first clamping groove, and a first spatial resolution module which is transversely arranged is arranged on the first clamping groove; the lower end of one end of the first positioning seat is provided with a first semi-cylinder, and the upper end of one end of the second positioning seat is provided with a second semi-cylinder; the two semi-cylinders are clamped by a locating pin; the first half cylinder is provided with a sliding block mechanism connected with a spring, so that the first spatial resolution module is flatly attached to the other end of the first clamping groove; the second semi-cylinder is provided with a sliding block mechanism connected with a spring, so that the first resolution module is attached to the lower surface of the first clamping groove; the second spatial resolution module is arranged in a second clamping groove of the second position seat; the rear end of the second semi-cylinder is provided with a sliding block mechanism connected with a spring, so that the second spatial resolution module is attached to the rear end face of the second clamping groove; the invention can detect CT image performance.
Description
Technical Field
The invention belongs to the field of micro CT metering, and particularly relates to a micro CT image spatial resolution die body with a positioning device.
Background
With the development of scientific technology, ordinary CT cannot meet the severe requirement of scientific research on high resolution, and Micro CT (Micro-computed tomography, micro-CT, mu-CT) has been developed. Micro-CT is a miniature CT machine, is a device for carrying out ultra-high resolution three-dimensional imaging by adopting an X-ray imaging principle, and can carry out high-resolution (tens of micrometers to submicron level) X-ray imaging on in-vitro samples such as bones, teeth, biological materials and living animals under the condition of not damaging the samples so as to acquire detailed three-dimensional structure information inside the samples. Micro-CT has become an important fast and nondestructive high-resolution three-dimensional imaging tool in biology and materials, and in addition, micro-CT has wide application prospect in the fields of archaeology, geology, industry and the like. The advent of new Micro focal spot X-ray sources, new reconstruction algorithms, hardware acceleration techniques, and improvements in computer performance, and the driving of simultaneously acquiring various structural, functional, and molecular information of a living being, will necessarily drive Micro-CT to develop toward high contrast, ultra-high resolution, fast real-time, and multi-modal imaging. Therefore, the standard phantom can be provided for Micro-CT, and the method has important significance in quality control and mass transfer calibration of parameters such as layer thickness and the like, and is promoted to develop.
At present, a body mold of CT, MRI and the like which are clinically used is fine in body mold molding process of Micro-CT, small in size and in the range of 100 nanometers to 10 micrometers, and certain difficulty and exploratory property exist in manufacturing depending on the Micro-nanometer processing process developed at present. At present, a phantom for metering and detecting CT equipment is found in China, but a layer thickness module for evaluating Micro-CT image performance is not reported.
Disclosure of Invention
The invention aims to provide a Micro CT image spatial resolution die body with a positioning device, which is used for detecting Micro-CT image performance.
The technical solution for realizing the purpose of the invention is as follows:
a microscopic CT image spatial resolution die body with a positioning device comprises a first fixing seat, a second fixing seat, a positioning pin, a first spatial resolution module, a first elastic piece, a first positioning block, a first blocking screw, a second elastic piece, a second positioning block, a second blocking screw, a third elastic piece, a third positioning block, a third blocking screw and a second spatial resolution module; the lower end of one end of the first fixing seat is provided with a first semi-cylinder, and the upper end of one end of the second fixing seat is provided with a second semi-cylinder; the first semi-cylinder and the second semi-cylinder are clamped by a positioning pin;
the upper end of the first semi-cylinder is provided with a first clamping groove for installing a first spatial resolution module which is transversely arranged; after the first spatial resolution module is placed in the first clamping groove, the first spatial resolution module is slightly higher than the upper end surface of the first clamping groove; the first semi-cylinder is provided with a first mounting hole along the radial direction, and the first elastic piece is arranged in the first mounting hole; the side end of the first clamping groove is provided with a first positioning groove, and the first positioning groove is positioned between the first mounting hole and the first clamping groove; the first positioning block is positioned in the first positioning groove and can slide in the first positioning groove along the radial direction of the first fixing seat; the first blocking screw is fixed in the first mounting hole so as to support one end of the first elastic piece, and the other end of the first elastic piece is fixedly connected with the first positioning block; the first positioning block pushes the first spatial resolution module to be flatly attached to the end face of the other end of the first clamping groove under the action of the first elastic piece;
the second semi-cylinder is provided with a second mounting hole along the radial direction, the second elastic piece is arranged in the second mounting hole, and the lower end of the second semi-cylinder is provided with a second positioning groove; the second positioning block is arranged in the second positioning groove and can slide in the second positioning groove along the radial direction of the second fixing seat; the second blocking screw is fixed in the second mounting hole so as to support one end of the second elastic piece, and the other end of the second elastic piece is fixedly connected with the second positioning block; the second positioning block downwards pushes the first spatial resolution module to be attached to the lower surface of the first clamping groove under the action of the second elastic piece;
a third mounting hole is formed in the rear end of the second semi-cylinder in the axial direction, and a second clamping groove is formed between the rear end of the second semi-cylinder and the second fixing seat main body so as to mount a second spatial resolution module; a third positioning groove is formed between the third mounting hole and the second clamping groove; the third elastic piece is arranged in the third mounting hole; the third positioning block is arranged in the third positioning groove and can slide in the third positioning groove; the third blocking screw is fixed in the third mounting hole so as to support one end of the third elastic piece, and the other end of the third elastic piece is fixedly connected with the third positioning block; and the third positioning block pushes the second spatial resolution module to be attached to the rear end surface of the second clamping groove under the action of the third elastic piece.
Compared with the prior art, the invention has the remarkable advantages that:
(1) The spatial resolution die body is provided with the spatial resolution module, and the spatial resolution module is provided with the marked line pair card, so that the device can be used for detecting the performance of Micro-CT images.
(2) According to the spatial resolution die body, the spatial resolution modules are positioned through the positioning blocks, so that the two spatial resolution modules are mutually perpendicular, and the problem of inaccurate measurement precision caused by inclination of line pair cards of the two spatial resolution modules is avoided.
(3) According to the spatial resolution die body, the size of the first clamping groove is slightly larger than that of the first spatial resolution module, and different types of spatial resolution modules can be replaced according to requirements.
The invention is described in further detail below with reference to the accompanying drawings.
Drawings
Fig. 1 is a schematic view of a spatial resolution phantom in a stereoscopic configuration according to the present invention.
FIG. 2 is a schematic diagram of the overall assembly of the spatial resolution phantom of the present invention.
Fig. 3 is a front view of the first fixing base provided with the first spatial resolution module.
Fig. 4 is a right side view of the first fixing base provided with the first spatial resolution module.
Fig. 5 is a top view of the first fixing base.
Fig. 6 is a cross-sectional top view of the clamping groove on the first fixing seat.
Fig. 7 is a right side view of the first fixing base.
Fig. 8 is a front view of a second spatial resolution module disposed on a second fixing base.
FIG. 9 is a cross-sectional view of a second spatial resolution module A-A disposed on a second mount.
Fig. 10 is a cross-sectional view of the clamping groove on the second fixing seat.
Fig. 11 is a sectional view of the second fixing base B-B.
Fig. 12 is a left side view of the second holder.
Fig. 13 (a-b) are front and left side views, respectively, of the positioning block.
Fig. 14 is a schematic diagram of a combined spatial resolution phantom.
Detailed Description
For the purpose of illustrating the technical scheme and technical purposes of the present invention, the present invention is further described below with reference to the accompanying drawings and specific embodiments.
Referring to fig. 1-14, the spatial resolution phantom with a positioning device for a micro CT image of the present invention includes a first fixing seat 1, a second fixing seat 2, a positioning pin 3, a first spatial resolution module 4, a first elastic member 5, a first positioning block 6, a first blocking screw 7, a second elastic member 8, a second positioning block 9, a second blocking screw 10, a third elastic member 11, a third positioning block 12, a third blocking screw 13, and a second spatial resolution module 14;
the main bodies of the first fixing seat 1 and the second fixing seat 2 are cylindrical; the lower end of one end of the first fixing seat 1 is provided with a first semi-cylinder 1-1, and the upper end of one end of the second fixing seat 2 is provided with a second semi-cylinder 2-1; the first semi-cylinder 1-1 and the second semi-cylinder 2-1 are clamped by a positioning pin 3, so that the first fixing seat 1 and the second fixing seat 2 can be spliced into a whole cylinder;
the upper end of the first semi-cylinder 1-1 is provided with a first clamping groove 1-2 for installing a first spatial resolution module 4 which is transversely arranged; the depth of the first clamping groove 1-2 is smaller than the thickness of the first spatial resolution module 4, so that after the first spatial resolution module 4 is placed in the first clamping groove 1-2, the first spatial resolution module 4 is slightly higher than the upper end face of the first clamping groove 1-2; the first semi-cylinder 1-1 is provided with a first mounting hole 1-3 along the radial direction, and the first elastic piece 5 is arranged in the first mounting hole 1-3; the side end of the first clamping groove 1-2 is provided with a first positioning groove 1-4, and the first positioning groove 1-4 is positioned between the first mounting hole 1-3 and the first clamping groove 1-2; the first positioning block 6 is positioned in the first positioning groove 1-4 and can slide in the first positioning groove 1-4 along the radial direction of the first fixing seat 1; the first blocking screw 7 is fixed in the first mounting hole 1-3 so as to support one end of the first elastic piece 5, and the other end of the first elastic piece 5 is fixedly connected with the first positioning block 6; the first positioning block 6 pushes the first spatial resolution module 4 under the action of the first elastic piece 5, so that the first spatial resolution module 4 is flatly attached to the end face of the other end of the first clamping groove 1-2, the first spatial resolution module 4 is ensured not to shake in the horizontal direction, and the end face of the other end of the first clamping groove 1-2 is used as a positioning face of the first spatial resolution module 4 in the horizontal direction.
The second semi-cylinder 2-1 is provided with a second mounting hole 2-2 along the radial direction, the second elastic piece 8 is arranged in the second mounting hole 2-2, and the lower end of the second semi-cylinder 2-1 is provided with a second positioning groove 2-8; the second positioning block 9 is arranged in the second positioning groove 2-8 and can slide in the second positioning groove 2-8 along the radial direction of the second fixing seat 2; the second blocking screw 10 is fixed in the second mounting hole 2-2 to support one end of the second elastic piece 8, and the other end of the second elastic piece 8 is fixedly connected with the second positioning block 9; the second positioning block 9 pushes the first spatial resolution module 4 downwards under the action of the second elastic piece 8, so that the first spatial resolution module 4 is attached to the lower surface of the first clamping groove 1-2;
a third mounting hole 2-3 is arranged at the rear end of the second semi-cylinder 2-1 along the axial direction, and a second clamping groove 2-4 is arranged between the rear end of the second semi-cylinder 2-1 and the main body of the second fixing seat 2 so as to mount a second spatial resolution module 14; the second spatial resolution module 14 is the same size as the second card slot 2-4. A third positioning groove 2-5 is arranged between the third mounting hole 2-3 and the second clamping groove 2-4; the third elastic piece 11 is arranged in the third mounting hole 2-3; the third positioning block 12 is arranged in the third positioning groove 2-5 and can slide in the third positioning groove 2-5; the third blocking screw 13 is fixed in the third mounting hole 2-3 to support one end of the third elastic element 11, and the other end of the third elastic element 11 is fixedly connected with the third positioning block 12; the third positioning block 12 pushes the second spatial resolution module 14 under the action of the third elastic piece 11, so that the second spatial resolution module 14 is attached to the rear end face of the second clamping groove 2-4. The rear end face of the second clamping groove 2-4 is used as a positioning face in the vertical direction of the second spatial resolution module 14. The positioning of the first clamping groove 1-2 and the second clamping groove 2-4 ensures that the first spatial resolution module 4 and the second spatial resolution module 14 are perpendicular to each other.
In some embodiments, the first fixing base 1 is provided with a plurality of positioning pins 3, the second fixing base 2 is provided with a plurality of positioning holes 15, and the positioning pins 3 on the first fixing base 1 are inserted into the positioning holes 15 on the second fixing base 2, so that the first fixing base 1 and the second fixing base 2 are spliced into a whole cylinder.
In other embodiments, the second fixing base 2 is provided with a plurality of positioning pins 3, the first fixing base 1 is provided with a plurality of positioning holes, and the positioning pins 3 on the second fixing base 2 are inserted into the positioning holes on the first fixing base 1, so that the first fixing base 1 and the second fixing base 2 are spliced into a whole cylinder.
Further, referring to fig. 13 (a-b), the contact ends of the second positioning block 9, the third positioning block 12 and the spatial resolution module are in an n-shaped arch shape, and the arch presses the edge of the spatial resolution module, so that the pressing surface is uniformly stressed.
In some embodiments, the first elastic member 5, the second elastic member 8, and the third elastic member 11 are plastic springs.
In other embodiments, the first elastic member 5, the second elastic member 8, and the third elastic member 11 are all made of elastic rubber.
Further, the first spatial resolution module 4 and the second spatial resolution module 14 are respectively provided with a plurality of line pair cards formed by different line pairs, the line distances between the line pair cards are different, the highest-level line pair which can be resolved by a scanned image is n line pairs per cm through Micro-CT scanning, and then the spatial resolution of the device is nLp/cm.
The line pair cards on the first spatial resolution module 4 and the second spatial resolution module 14 are respectively provided with a photoetching template, and then the line pair cards containing lead with equal interval stripes are obtained on the first spatial resolution module 4 and the second spatial resolution module 14 by a vacuum spraying technology. The line pair card is an important tool for objectively describing the resolution of a ray real-time imaging detection system and the quality index of the resolution of a real-time imaging detection image, and the space resolution is described by using the interval size of a resolvable group of line pairs with black and white intervals. Different pairs of line pair cards correspond to different spatial resolutions.
Furthermore, the whole spatial resolution die body with the positioning device is made of transparent nonmetallic materials.
The spatial resolution refers to the capability of the minimum geometric detail which can be resolved in a CT image, can directly reflect the detection performance of a Micro-CT system, and is defined as the smallest circular aperture or the line pair number with black and white phase (the density difference is the same) when CT values of two substances are different by more than 100HU, and the unit is mm or Lp/mm. When the micro CT image spatial resolution die body with the positioning device is used, the first spatial resolution module 4 and the second spatial resolution module 14 are respectively arranged in the first clamping groove 1-2 and the second clamping groove 2-4; the first fixing seat 1 and the second fixing seat 2 are clamped into a whole, and the first spatial resolution module 4 and the second spatial resolution module 14 are mutually perpendicular through positioning blocks, as shown in fig. 14; the width of the first clamping groove 1-2 is slightly larger than the size of the first spatial resolution module 4, and different spatial resolution modules can be replaced according to the requirement. Placing the combined die body in a cylindrical scanning cavity on a scanning table of a Micro-CT; and selecting standard conditions to perform single-layer scanning on the resolution module of the die body. The first spatial resolution module 4 which is horizontally arranged can detect the resolution of the Micro-CT according to the resolution of a scanned image through the Micro-CT scanning; and (3) combining horizontal arrangement and vertical arrangement, and obtaining a tomographic image of a line pair card in a die body or a reconstructed image in the horizontal direction through Micro-CT scanning reconstruction, wherein the spatial resolution level of the Micro-CT image can be obtained through the observation of the line pair in the image, so that the detection of the spatial resolution of a detectable Micro-CT system is completed.
Claims (7)
1. The micro CT image spatial resolution die body with the positioning device is characterized by comprising a first fixing seat (1), a second fixing seat (2), a positioning pin (3), a first spatial resolution module (4), a first elastic piece (5), a first positioning block (6), a first blocking screw (7), a second elastic piece (8), a second positioning block (9), a second blocking screw (10), a third elastic piece (11), a third positioning block (12), a third blocking screw (13) and a second spatial resolution module (14); the lower end of one end of the first fixing seat (1) is provided with a first semi-cylinder (1-1), and the upper end of one end of the second fixing seat (2) is provided with a second semi-cylinder (2-1); the first semi-cylinder (1-1) is clamped with the second semi-cylinder (2-1) through a positioning pin (3);
the upper end of the first semi-cylinder (1-1) is provided with a first clamping groove (1-2) for installing a first spatial resolution module (4) which is transversely arranged; after the first spatial resolution module (4) is placed in the first clamping groove (1-2), the first spatial resolution module (4) is slightly higher than the upper end face of the first clamping groove (1-2); the first semi-cylinder (1-1) is provided with a first mounting hole (1-3) along the radial direction, and the first elastic piece (5) is arranged in the first mounting hole (1-3); the side end of the first clamping groove (1-2) is provided with a first positioning groove (1-4), and the first positioning groove (1-4) is positioned between the first mounting hole (1-3) and the first clamping groove (1-2); the first positioning block (6) is positioned in the first positioning groove (1-4) and can slide in the first positioning groove (1-4) along the radial direction of the first fixing seat (1); the first blocking screw (7) is fixed in the first mounting hole (1-3) to support one end of the first elastic piece (5), and the other end of the first elastic piece (5) is fixedly connected with the first positioning block (6); the first positioning block (6) pushes the first spatial resolution module (4) to be flatly attached to the end face of the other end of the first clamping groove (1-2) under the action of the first elastic piece (5);
the second semi-cylinder (2-1) is provided with a second mounting hole (2-2) along the radial direction, the second elastic piece (8) is arranged in the second mounting hole (2-2), and the lower end of the second semi-cylinder (2-1) is provided with a second positioning groove (2-8); the second positioning block (9) is arranged in the second positioning groove (2-8) and can slide in the second positioning groove (2-8) along the radial direction of the second fixing seat (2); the second blocking screw (10) is fixed in the second mounting hole (2-2) so as to support one end of the second elastic piece (8), and the other end of the second elastic piece (8) is fixedly connected with the second positioning block (9); the second positioning block (9) pushes the first spatial resolution module (4) downwards to be attached to the lower surface of the first clamping groove (1-2) under the action of the second elastic piece (8);
a third mounting hole (2-3) is formed in the rear end of the second semi-cylinder (2-1) along the axial direction, and a second clamping groove (2-4) is formed between the rear end of the second semi-cylinder (2-1) and the main body of the second fixing seat (2) so as to mount a second spatial resolution module (14); a third positioning groove (2-5) is arranged between the third mounting hole (2-3) and the second clamping groove (2-4); the third elastic piece (11) is arranged in the third mounting hole (2-3); the third positioning block (12) is arranged in the third positioning groove (2-5) and can slide in the third positioning groove (2-5); the third blocking screw (13) is fixed in the third mounting hole (2-3) so as to support one end of the third elastic piece (11), and the other end of the third elastic piece (11) is fixedly connected with the third positioning block (12); the third positioning block (12) pushes the second spatial resolution module (14) to be attached to the rear end face of the second clamping groove (2-4) under the action of the third elastic piece (11); positioning the spatial resolution modules through a plurality of positioning blocks to enable the two spatial resolution modules to be perpendicular to each other;
the first clamping groove is slightly larger than the first spatial resolution module in size.
2. The self-positioning device-equipped micro-CT image spatial resolution phantom according to claim 1, wherein the first fixing seat (1) is provided with a plurality of positioning pins (3), the second fixing seat (2) is provided with a plurality of positioning holes (15), and the positioning pins (3) on the first fixing seat (1) are inserted into the positioning holes (15) on the second fixing seat (2), so that the first fixing seat (1) and the second fixing seat (2) are spliced into a whole cylinder.
3. The spatial resolution phantom of a micro-CT image with a positioning device according to claim 1, wherein the second fixing base (2) is provided with a plurality of positioning pins (3), the first fixing base (1) is provided with a plurality of positioning holes, and the positioning pins (3) on the second fixing base (2) are inserted into the positioning holes on the first fixing base (1), so that the first fixing base (1) and the second fixing base (2) are spliced into a whole cylinder.
4. The spatial resolution phantom of the micro-CT image with the positioning device according to claim 1, wherein the contact ends of the second positioning block (9), the third positioning block (12) and the spatial resolution module are arched, and the arched presses the edge of the spatial resolution module.
5. The self-positioning device-equipped micro-CT image spatial resolution phantom according to claim 1, wherein the first elastic member (5), the second elastic member (8) and the third elastic member (11) are all plastic springs.
6. The self-positioning device-equipped micro-CT image spatial resolution phantom according to claim 1, wherein the first elastic member (5), the second elastic member (8) and the third elastic member (11) are made of elastic rubber.
7. The spatial resolution phantom of a micro-CT image with a positioning device according to claim 1, wherein the first spatial resolution module (4) and the second spatial resolution module (14) are provided with a plurality of pairs of line pair cards formed by different pairs of line pairs.
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