CN109222987A - A kind of respiratory effort identification equipment and its application apparatus - Google Patents

A kind of respiratory effort identification equipment and its application apparatus Download PDF

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Publication number
CN109222987A
CN109222987A CN201811273649.5A CN201811273649A CN109222987A CN 109222987 A CN109222987 A CN 109222987A CN 201811273649 A CN201811273649 A CN 201811273649A CN 109222987 A CN109222987 A CN 109222987A
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China
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nose
wing
sensor
signal
processor
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CN201811273649.5A
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Chinese (zh)
Inventor
徐现红
戴涛
邓研辉
王奕刚
张亮
王启帆
吕其元
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SILAN TECHNOLOGY (CHENGDU) Co Ltd
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SILAN TECHNOLOGY (CHENGDU) Co Ltd
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Priority to CN201811273649.5A priority Critical patent/CN109222987A/en
Publication of CN109222987A publication Critical patent/CN109222987A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/113Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4818Sleep apnoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • A61B5/6819Nose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Otolaryngology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The present invention relates to one kind to identify equipment for respiratory effort, and described one kind includes: wing of nose action sensor for respiratory effort equipment, for acquiring wing of nose action signal;Processor is configured as: coupled with wing of nose action sensor, receive wing of nose action sensor wing of nose action signal and analyze wing of nose action signal determine whether occur respiratory effort.The invention further relates to the sleep apnea monitoring devices and its application method of a kind of application respiratory effort identification equipment.

Description

A kind of respiratory effort identification equipment and its application apparatus
Technical field
The present invention relates to a kind of respiratory effort identification equipment and the device and method of sleep apnea monitoring, more particularly to Measurement for wing of nose action signal, and judge whether subject carries out respiratory effort with wing of nose action signal.
Background technique
Sleep apnea syndrome becomes the research hotspot of medical field in recent years, according to " U.S.'s sleep medicine meeting (AASM) interpretation standard ", sleep apnea event can be divided into obstructive type apnea, maincenter type apnea and mixed type and exhale Inhale pause;When apnea occurs, there is the respiratory effort for continuing or enhancing during entire air-flow missing, then it is assumed that be Obstructive type apnea;If respiratory effort is not present during entire respiratory air flow missing, then it is assumed that be maincenter type apnea;If Breathe no more effort but event latter half respiratory effort of apnea start-up portion restores, then it is assumed that is that mixed type breathing is temporary Stop.
The goldstandard of monitoring respiratory effort is to be tested by Esophageal Pressure, but Esophageal Pressure test is a kind of intrusive test, Easily cause subject uncomfortable and is difficult to carry out whole night.Currently, the mode instead of Esophageal Pressure monitoring respiratory effort of extensive utilization is Impedance caused by thorax abdomen respiratory movement or inductance variation are measured, such as breathing is carried out by chest and abdomen piezo strip or chest electrode piece and is exerted The monitoring of power.
Currently, sleep analysis monitor (PSG) is the goldstandard for clinically diagnosing sleep apnea syndrome, it is most of The monitoring still moved by chest and abdomen when PSG is tested is to determine whether there is respiratory effort, and PSG can be same in sleep whole night When monitoring human body multi-channal physiological and more monitoring result parameter can be calculated.But in practical applications, lead sleep more Monitoring device volume is big, portability is poor, system complex, cumbersome, and tester needs could be complete under the assistance of medical staff At test;Wearing comfort is poor during the test by tester, and hospital environment greatly influences the sleep quality of patient.
Existing Portable sleep monitoring of respiration equipment is generally integrated multiple sensors in one, generally includes nasal airflow prison Module, ECG module, chest and abdomen motion module are surveyed, such form inevitably causes subject wears uncomfortable, and especially nasal airflow is supervised Survey and both chest and abdomen motion modules for monitoring respiratory effort are placed in the different parts of subject, and cable is various, using easypro Suitable sense is low.
Qian Hong's jade proposes bones of the body lingualis or the wing of nose when nasal respiration in " research of obstructive respiration sleep suspend and nasal airway resistance " The enhancing when myoelectricity of flesh includes relatively nasal obstruction and mouth breathing;Li Xiaoming points out normal person's nose in " the current limliting segment of nose air flue " With respiratory movement isometric contraction occurs for musculus pterygoideus, maintains dilator naris air flue to stablize with this constant, in vestibulum nasi in addition to wing of nose tissue Resistance to deformation effect is outer, and compliance relies primarily on wing of nose flesh and changes with transmural pressure power difference in respiratory and occur quick anti- Activity is answered to adjust, respiratory movement amplitude is shown as and deepens to increase, the contraction movement of wing of nose flesh also enhances therewith.
Summary of the invention
Present invention solves the technical problem that being to provide a kind of sleep breath monitoring device intensive, usage comfort is good.
Above-mentioned technical problem provide through the invention foundation wing of nose action signal determine respiratory effort method and according to Respiratory effort for executing this method of the invention identifies equipment and sleep breath monitoring system device to solve.
The present invention determines the method for respiratory effort by the wing of nose movement sensing of detection wing of nose action signal according to wing of nose signal Device and the processor of analysis wing of nose action signal are realized.Wing of nose movement includes wing of nose expansion and nasal ala retracted, steadily when breathing, The wing of nose keeps slight contraction and expansion, the balance of maintenance air passage gas flow;When expiratory dyspnea, the wing of nose is in autonomic control Lower increase expansion amplitude is to improve air-flow disengaging flow;Nasal blockage, when using mouth breathing, although nasal cavity apnea air-flow, The movement of expansion and contraction when the wing of nose still maintains breathing.Wing of nose action sensor is exactly the sensing for detecting wing of nose motion amplitude Device, the i.e. sensor of expansion and contraction degree.
Further, cooperate nasal airflow sensor, the above method also can be used to carry out the Classification and Identification of sleep apnea. For example, if analysis wing of nose action signal determination has respiratory effort to recognize this apnea in apnea Determine obstructive type;Analysis wing of nose action signal determines that then apnea is identified as maincenter type for the effort that breathes no more.
The present invention also provides a kind of equipment of respiratory effort for identification, and the equipment includes: wing of nose action sensor, For acquiring wing of nose action signal;Processor is configured as: being coupled with wing of nose action sensor, is received wing of nose action sensor Wing of nose action signal and analyze wing of nose action signal determine whether occur respiratory effort;Storage unit, with the processor electricity Connection, the analysis result for storage processor.
In exemplary embodiment provided by the invention, wing of nose action sensor can select optical sensor or acceleration Sensor, in addition, also can be selected piezoelectric transducer, myoelectric sensor, electric resistance sensor or other can reflect wing of nose action signal Sensor.
In exemplary embodiment provided by the invention, the equipment of the respiratory effort for identification further includes a substrate, In on subject's nose, the wing of nose action sensor is fixed in the substrate substrate Pasting, it is ensured that substrate paste with When subject's nose, the wing of nose action sensor is located just at wing of nose position, can accurately acquire wing of nose action signal.
The present invention also provides a kind of devices for sleep apnea monitoring, and described device includes for acquiring the wing of nose The wing of nose action sensor of action signal, it is described for acquiring the mouth and nose gas flow transducer and processor of respiratory air flow signal Processor is configured as: coupled respectively with wing of nose action sensor and nasal airflow sensor, for receive wing of nose action signal and Respiratory air flow signal;Analysis wing of nose action signal determines whether that respiratory effort occurs, analyzes respiratory air flow signal and determine whether to send out Raw apnea determines that apnea type is maincenter type or obstructive type;The storage unit being electrically connected with the processor is used In the analysis result for receiving and storing processor.
Further, thermistor or pressure sensor can be selected in the mouth and nose gas flow transducer;It should be noted, mouth and nose gas The respiratory air flow signal of flow sensor acquisition includes nasal airflow signal and mouth breathing airflow signal.
Further, the sleep apnea monitoring device may also include blood oxygen transducer, and body moves sensor, alarm Unit, display unit.
The present invention provides a kind of method and apparatus that completely new identification of breathing is made great efforts, the acquisition of wing of nose action signal is compared It is more comfortable in the acquisition of Esophageal Pressure signal;It is more convenient compared to the acquisition of thoracic impedance signal.
The sleep apnea monitoring device provided through the invention, respiratory effort and nasal airflow are detected in nose, real Existing signal acquisition is concentrated, easy to use, the good effect of comfort.
Detailed description of the invention
Fig. 1 shows a kind of frame diagram of respiratory effort identification equipment;
Fig. 2 shows a kind of internal structure charts of respiratory effort identification equipment;
Fig. 3 shows a kind of wearing figure of respiratory effort identification equipment;
Fig. 4 shows a kind of frame diagram of sleep apnea monitoring device;
Fig. 5 shows a kind of schematic diagram of sleep apnea monitoring device;
Fig. 6 shows a kind of internal structure chart of sleep apnea monitoring device;
Fig. 7 shows a kind of wearing figure of sleep apnea monitoring device;
Fig. 8 shows a kind of flow chart of monitoring sleep apnea.
Specific embodiment
Embodiment one
Fig. 1,2 show a kind of respiratory effort identification equipment 100 according to the present invention.
Respiratory effort identifies that equipment 100 includes soft shell 110 and internal electronic element.The substrate 111 of soft shell 110 For the flexible material of biocompatibility close friend a kind of, and its Pasting is on subjects skin.Flexible electricity in soft shell 110 Road plate 150 and the wing of nose action sensor 120 being fixed on flexible circuit board 150, microprocessor 130 and storage unit 140. Wing of nose action sensor 120 can be optical sensor, acceleration transducer, tension sensing for detecting wing of nose action signal Any one of device, myoelectric sensor, piezoelectric transducer;It include transmitting unit and receiving unit if selecting optical sensor. Microprocessor 130 is electrically connected with wing of nose action sensor 120, receives wing of nose action signal and is analyzed and processed and identifies whether to send out Raw respiratory effort, and transmit the result to storage unit 140 and stored.
Respiratory effort identify equipment 100 wearing mode can with as shown in figure 3,111 a part of substrate is pasted on nose, A part is pasted near nose on the face.To paste substrate 111 closely with nose and face, soft shell 110 is also set Have a bending part 112, bending part 112 is accordion, not with skin adhesive.It is in 110 part of soft shell being pasted on nose Wing of nose action sensor 120, and be affixed in 110 part of soft shell on the face as microprocessor 130 and storage unit 140.
When identification of breathing effort equipment 100 is worn on subject's nose, substrate 111 is pasted on subject's nose When it is ensured that wing of nose action sensor 120 is located just on the wing of nose, it is preferred that be located at the nearly nostril one end of the wing of nose, with obtain it is most quick The wing of nose action signal of sense is based on this, and for the visual angle of Fig. 3, wing of nose action sensor 120 should be located at respiratory effort identification and set Standby 100 are affixed in the part on nose, and the distance of the lower edge to respiratory effort identification equipment is preferred no more than 3mm.
To keep the signal of the acquisition of wing of nose action sensor 120 more acurrate, substrate 111 is equipped with opening so that the wing of nose is dynamic Making sensor 120 can directly contact with the wing of nose.
In addition to the embodiments described above, it does not mention when wing of nose action sensor 120, microprocessor 130 and storage unit 140 and And size of power it is sufficiently small when, identification of breathing make great efforts equipment 100 can entirely be pasted on the wing of nose, do not need to be arranged at this time curved Folding part 112.
In addition to the embodiments described above, respiratory effort identification equipment 100 can also be set there are two wing of nose action sensor, be adopted respectively The signal in two nostrils in collection left and right.
In addition to the embodiments described above, the also settable nothing communicated with microprocessor 130 in respiratory effort identification equipment 100 Result can be sent to exterior display device or other equipment by line transmission unit and alarm unit, wireless transmission unit;When miniature When the result of respiratory effort is not occurred for processor 130, alarm unit is sounded an alarm.
Embodiment two
Fig. 4,5,6 show a kind of sleep apnea monitoring device 200, and Fig. 7 shows its wearing mode.
From the appearance point of view, sleep apnea monitoring device 200 includes soft shell 210 and mouth and nose air-flow collection tube 260. Soft shell 210 is equipped with bending part 212, and soft shell 210 can be made to be bent into the shape suitable for nose, soft shell 210 Substrate 211 can directly be pasted with subjects skin.It is equipped with thermistor or pressure sensor in mouth and nose air-flow collection tube 260, uses In acquisition breath signal, mouth and nose air-flow collection tube 260 is bent, when use by three conduits respectively branch to nostril and mouth It can.
It is equipped with a flexible circuit board 250 in soft shell 210, is fixed with wing of nose motion sensor on flexible circuit board 250 220, microprocessor 230 and storage unit 240, flexible circuit board 250 pass through in conducting wire 261 and mouth and nose air-flow collection tube 260 Sensor electrical connection.
Wing of nose action sensor 120 for detecting wing of nose action signal, can be optical sensor, acceleration transducer, Any one of tension sensor, myoelectric sensor, piezoelectric transducer;If selecting optical sensor, comprising transmitting unit and Receiving unit.Wing of nose action sensor 120 is electrically connected by flexible circuit board 250 with microprocessor 230.To pass wing of nose movement The wing of nose action signal that sensor 120 acquires is sensitiveer, opening is equipped in substrate 211, to make wing of nose action sensor 120 can Directly contacted with the wing of nose.
Microprocessor 230 receives wing of nose action signal acquire from wing of nose action sensor 120 and comes from mouth and nose gas The respiratory air flow signal of flow tube 260, and carry out processing analysis.Microprocessor 230 judges whether by respiratory air flow signal Existing apnea, and analyze and moved when there is apnea with the presence or absence of the wing of nose, that is, it whether there is respiratory effort, if existing simultaneously Respiratory effort, it is determined that this time event is obstructive type apnea;Respiratory effort is lacked when if apnea occur, it is determined that this Secondary event is maincenter type apnea;More complexly, if interior apnea effort at the beginning of respiration suspending event, later There are respiratory efforts then to determine that this event is mixed type apnea.Result is sent to storage unit by microprocessor 230 In 240.
Sleep apnea monitoring device 200 may also include blood oxygen transducer 280 and body and move sensor 270, and and color It is set on flexible circuit board 250, can be communicated with microprocessor 230.Blood oxygen transducer 280 includes that light emitting unit connects with light Unit is received, substrate 211 is equipped with opening in the corresponding position of blood oxygen transducer 280, accurately to detect the blood oxygen of wing of nose position Saturation degree.Body is moved sensor 270 and is such as lain on the back, lateral sleeping position using three axis accelerometer for acquiring subject's body movement signal Deng.
To keep the volume of sleep breath monitoring device 200 small as far as possible, flexible circuit board 250 uses double-sided PCB, Wing of nose action sensor 220 and blood oxygen transducer 280 are set to the ipsilateral of flexible circuit board 250, and the substrate 211 of corresponding position Equipped with opening, preferably to acquire signal;And other units can be set to the other side of flexible circuit board 250.Meanwhile the wing of nose is dynamic Make sensor 220 and blood oxygen transducer 280 is located at the both sides of bending part 212.
In addition, sleep apnea monitoring device 200 may also include wireless data transmission unit not shown in the figure, it is used for The analysis result of microprocessor 230 is sent in outernal display unit or other equipment, wherein analysis result includes blood oxygen Saturation degree, apnea type.
Embodiment three
Fig. 8 shows the flow diagram of sleep apnea monitoring of the invention.
A kind of method of sleep apnea monitoring provided by the invention comprises the steps of:
The first step acquires the respiratory air flow signal and wing of nose action signal of mouth and nose.
Second step judges whether apnea occur according to respiratory air flow signal;If not occurring apnea Then without subsequent step.
Third step judges apnea type according to wing of nose action signal: dividing within the time for apnea occur The wing of nose action signal in the time is analysed with the presence or absence of wing of nose respiratory effort;If in apnea, analysis wing of nose movement Signal, which determines, has respiratory effort that this apnea is then assert obstructive type;Analysis wing of nose action signal determination breathes no more Make great efforts then apnea and is identified as maincenter type.
4th step exports the type of final apnea.
Above-mentioned sleep apnea monitoring method further includes acquisition body movement signal and blood oxygen saturation, and temporary in output breathing Stop both output signal when event type.
Above-described embodiment only describes and presents the present invention, and the present invention is not limited to the range of embodiment disclosed above, Ren Hehan It covers within the scope of the claims or equivalent modification and belongs to the scope of the present invention.

Claims (10)

1. a kind of respiratory effort identifies equipment, comprising: one or more is for acquiring the wing of nose movement sensing of wing of nose action signal Device;And the processor coupled with wing of nose action sensor, the processor is by analysis wing of nose action signal come identification of breathing Effort;Storage unit is electrically connected with the processor, the analysis result for storage processor.
2. a kind of respiratory effort according to claim 1 identifies equipment, which is characterized in that the wing of nose action sensor can Using the one or more of acceleration transducer, optical sensor, myoelectric sensor, piezoelectric transducer.
3. a kind of respiratory effort according to claim 1 identifies equipment, which is characterized in that the respiratory effort identifies equipment It further include soft shell, the substrate Pasting of the soft shell is equipped with flexibility on subjects skin in the soft shell Circuit board, the wing of nose action sensor, the processor and the storage unit are fixed on the flexible circuit board.
4. a kind of sleep apnea monitoring device, comprising: one or more is for acquiring the wing of nose movement of wing of nose action signal Sensor, for acquiring the mouth and nose gas flow transducer of respiratory air flow signal;And it is passed with wing of nose action sensor and mouth and nose air-flow The type of the processor of sensor coupling, the processor analysis wing of nose action signal and respiratory air flow signal to sleep apnea It is identified;The storage unit being electrically connected with the processor, for receiving and storing the analysis result of processor.
5. a kind of sleep apnea monitoring device according to claim 4, which is characterized in that the wing of nose movement sensing The one or more of acceleration transducer, optical sensor, myoelectric sensor, piezoelectric transducer can be used in device.
6. a kind of sleep apnea monitoring device according to claim 4, which is characterized in that the sleep breath monitoring Device includes soft shell, and the mouth and nose air-flow collection tube being fixedly connected with the soft shell, the base of the soft shell Bottom Pasting is equipped with flexible circuit board, the wing of nose action sensor, the place on subjects skin in the soft shell Reason device and the storage unit are fixed on the flexible circuit board;The mouth and nose gas flow transducer is set to mouth and nose air-flow collection tube It is interior, and the mouth and nose gas flow transducer is electrically connected with the flexible circuit board.
7. a kind of sleep apnea monitoring device according to claim 4, which is characterized in that on the flexible circuit board It is additionally provided with body and moves sensor and blood oxygen transducer.
8. a kind of method that identification of breathing is made great efforts, comprising: acquire wing of nose action signal by wing of nose action sensor;Processor connects It receives wing of nose action signal and carries out analysis to identification of breathing effort.
9. a kind of method of monitoring sleep apnea, comprising: by wing of nose action sensor acquire wing of nose action signal and Breath signal is acquired by mouth and nose gas flow transducer;Processor analysis breath signal and wing of nose action signal are to identify that sleep is exhaled It inhales suspending event and judges that sleep apnea event is maincenter type or obstructive type.
10. a kind of method of monitoring sleep apnea according to claim 9 further includes moving sensor acquisition by body Body movement signal and blood oxygen saturation is acquired by blood oxygen transducer;Processor analyzes breath signal, body movement signal and blood oxygen saturation Degree carry out sleep apnea event identification, and according to wing of nose action signal judge sleep apnea event be maincenter type also It is obstructive type.
CN201811273649.5A 2018-10-30 2018-10-30 A kind of respiratory effort identification equipment and its application apparatus Pending CN109222987A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022261208A3 (en) * 2021-06-11 2023-01-19 Dathomir Laboratories Llc Respiration detection

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CN107019495A (en) * 2017-03-13 2017-08-08 北京航空航天大学 Apnea detection and prior-warning device and method based on smart mobile phone and the mounted respiration transducer of nose
CN108634954A (en) * 2018-04-28 2018-10-12 上海健康医学院 A kind of simple apnea monitoring device of household

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Publication number Priority date Publication date Assignee Title
US20130008437A1 (en) * 2009-12-28 2013-01-10 Universite Francois Rabelais Device for oral administration of an aerosol for the rhinopharynx, the nasal cavities or the paranasal sinuses
US20120190998A1 (en) * 2011-01-25 2012-07-26 Resmed Limited Method and apparatus for detecting respiratory effort
CN103156612A (en) * 2011-12-09 2013-06-19 浩华科技实业有限公司 Respiratory monitor
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WO2022261208A3 (en) * 2021-06-11 2023-01-19 Dathomir Laboratories Llc Respiration detection

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