CN109221519A - A kind of hypoglycemic oligosaccharide probiotics solid beverage and preparation method thereof - Google Patents
A kind of hypoglycemic oligosaccharide probiotics solid beverage and preparation method thereof Download PDFInfo
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- CN109221519A CN109221519A CN201811114246.6A CN201811114246A CN109221519A CN 109221519 A CN109221519 A CN 109221519A CN 201811114246 A CN201811114246 A CN 201811114246A CN 109221519 A CN109221519 A CN 109221519A
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- hypoglycemic
- solid beverage
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- probiotics solid
- lactobacillus
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
- A23F3/30—Further treatment of dried tea extract; Preparations produced thereby, e.g. instant tea
Abstract
The invention discloses a kind of hypoglycemic oligosaccharide probiotics solid beverages and preparation method thereof, which includes following raw material: Oligomeric manna sugar, compound probiotic, stachyose, L-arabinose, green tea powder and inulin.The solid beverage is faint yellow slightly sweet band astringent taste, and in uniform powdered, the viable count of Bifidobacterium is up to 3.4 × 108CFU/g, viable count of lactobacillus is up to 1.2 × 109CFU/g；To the efficient up to 98% or more of diabetic population, the intervention of insulin and drug can be partially replaced, the usage amount of drug is reduced, it is helpful to the crowd in each diabetic history stage, to effect crowd's asexuality difference, diabetes can be assisted in the treatment of with composite medicine, in overall 15 days onset times；Preparation method is simple, implementation easy to operate.
Description
Technical field
The present invention relates to food processing technology fields, and in particular to it is a kind of it is hypoglycemic with oligosaccharide probiotics solid beverage and
Preparation method.
Background technique
Diabetes, be by inherent cause, immunologic function disorder, microorganism infection and its toxin, free radical toxin, spirit because
The various virulence factors such as element act on sugar, the protein, rouge that body leads to hypoinsulinism, insulin resistance etc. and causes
A series of metabolic disorder syndromes such as fat, water and electrolyte, clinically using hyperglycemia as main feature, typical case may occur in which more
The performance, i.e. " three-many-one-little " symptom such as urine, more drinks, more food, syntexis.Chang Bingfa heart, blood vessel, kidney, eye, the nervous system disease,
Ketoacidosis, nonketotic hyperosmolar diabetic coma can occur when serious, and be often accompanied by various infection, be that harmful to human is strong
A kind of more serious disease of health.In the world, 1 just suffers from diabetes in every 11 adults！Data source is in state
The 8th edition diabetes general view truthful data that border diabetes alliance (IDF) issues in " world's diabetes conference in 2017 ".General view
Introducing adult diabetic in world wide has 4.25 hundred million, diabetes most fast in developing country's growth rate, Chinese
Number is most, is 1.1 hundred million！Diabetes cannot eradicate at present, but blood glucose can be made steady in a long-term by rationally control, close to just
Often, diabetic can be as the happiness life normal person！
The treatment of existing diabetes mainly takes drugs as sulfonylurea drugs, insulin sensitizer, biguanides
Deng, but drug accordance with tolerance can be generated by taking drugs, and drug it is all more or less there is certain toxic side effect, be unfavorable for people
Body health.Also have using food therapy and alleviate, but food therapy therapeutic effect is bad, the progress for the treatment of is slow.Therefore, it is badly in need of out
The food of blood glucose can quickly be reduced by sending out a kind of, and accordance with tolerance is small, securely and reliably, be had no toxic side effect.
Summary of the invention
Aiming at the problems existing in the prior art, the purpose of the present invention is to provide a kind of hypoglycemic with oligosaccharide probiotics
Solid beverage and preparation method thereof, the solid beverage are faint yellow slightly sweet band astringent taste, in uniform powdered, the work of Bifidobacterium
Bacterium number is up to 3.4 × 108CFU/g, viable count of lactobacillus is up to 1.2 × 109CFU/g；To the efficient up to 98% of diabetic population
More than, the intervention of insulin and drug can be partially replaced, the usage amount of drug is reduced, it is equal to the crowd in each diabetic history stage
It is helpful, to effect crowd's asexuality difference, diabetes can be assisted in the treatment of with composite medicine, in overall 15 days onset times；It is made
Preparation Method is simple, implementation easy to operate.
In order to achieve the above object, the present invention is achieved by the following scheme.
(1) a kind of hypoglycemic oligosaccharide probiotics solid beverage, including following raw material used: Oligomeric manna sugar, compound prebiotic
Bacterium, stachyose, L-arabinose, green tea powder and inulin.
Preferably, the compound probiotic includes: bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and saliva cream
Bacillus.
Preferably, the dosage of the raw material are as follows: 8.0-9.6 parts of Oligomeric manna sugar, 0.7-1.1 parts of compound probiotic, wood
17.0-18.2 parts sugared, 50.0-50.6 parts of L-arabinose, 1.5-2.1 parts of green tea powder and 20.0-21.2 parts of inulin.
It is further preferred that the dosage of the raw material are as follows: 8.8 parts of Oligomeric manna sugar, 0.9 part of compound probiotic, stachyose
17.6 parts, 50.3 parts of L-arabinose, 1.8 parts of green tea powder and 20.6 parts of inulin.
Preferably, the compound probiotic includes: 3-5 parts of bifidobacterium lactis, 3-5 parts of lactobacillus plantarum, rhamnose cream bar
3-5 parts and Lactobacillus salivarius 3-5 parts of bacterium.
It is further preferred that bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and saliva in the compound probiotic
The mass ratio of lactobacillus is 1:1:1:1.
(2) a kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step: will be low
Poly- mannose, compound probiotic, stachyose, L-arabinose, green tea powder and inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide benefit
Raw bacterium solid beverage.
Preferably, the compound probiotic includes: bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and saliva cream
Bacillus.
Compared with prior art, the invention has the benefit that
The resulting hypoglycemic use oligosaccharide probiotics solid beverage of the present invention is faint yellow slightly sweet band astringent taste, is in uniform powder
Last shape, the viable count of Bifidobacterium is up to 3.4 × 108CFU/g, viable count of lactobacillus is up to 1.2 × 109CFU/g, viable count
Content is higher.
The resulting hypoglycemic improvement result for having conspicuousness to diabetes with oligosaccharide probiotics solid beverage of the present invention, it is right
The efficient of diabetic population can partially replace the intervention of insulin and drug, reduce the usage amount of drug up to 98% or more, right
The crowd in each diabetic history stage is helpful, to effect crowd's asexuality difference, can assist in the treatment of diabetes with composite medicine,
In overall 15 days onset times, body can effectively improve, optimize body vivo environment, be effectively relieved and prevent the hair of diabetes
It is raw.
The present invention it is resulting it is hypoglycemic with oligosaccharide in oligosaccharide probiotics solid beverage (Oligomeric manna sugar, arabinose,
Stachyose, inulin) and probiotics (bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius) itself is respectively
All have the function of reducing blood glucose, while oligosaccharide has proliferation function to probiotics, the two can interact significant decrease
The intracorporal blood-sugar content of people.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
It will be appreciated that the following example is merely to illustrate the present invention, and it is not construed as limiting the scope of the invention.
Embodiment 1
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 8.8% Oligomeric manna sugar, 0.9% compound probiotic, 17.6% stachyose, 50.3%L- arabinose, 1.8%
Green tea powder and 20.6% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 1:1:1:1.
Embodiment 2
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 8.0% Oligomeric manna sugar, 1.1% compound probiotic, 18.2% stachyose, 50.0%L- arabinose, 2.1%
Green tea powder and 20.6% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 3:5:4:4.
Embodiment 3
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 9.6% Oligomeric manna sugar, 0.7% compound probiotic, 17.0% stachyose, 50.6%L- arabinose, 2.1%
Green tea powder and 20.0% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 4:3:3:3.
Embodiment 4
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 8.8% Oligomeric manna sugar, 0.7% compound probiotic, 17.6% stachyose, 50.2%L- arabinose, 1.5%
Green tea powder and 21.2% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 1:1:1:1.
Embodiment 5
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 8.8% Oligomeric manna sugar, 1.1% compound probiotic, 17.0% stachyose, 50.3%L- arabinose, 2.1%
Green tea powder and 20.7% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 5:5:4:4.
Embodiment 6
A kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, including following preparation step:
By 9.6% Oligomeric manna sugar, 1.0% compound probiotic, 17.6% stachyose, 50.3%L- arabinose, 1.5%
Green tea powder and 20.0% inulin are uniformly mixed, and obtain hypoglycemic oligosaccharide probiotics solid beverage；Wherein in compound probiotic
Bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 3:3:5:5.
The resulting hypoglycemic use oligosaccharide probiotics solid beverage of above embodiments for major ingredient, is cooperated with " Oligomeric manna sugar "
Three kinds of arabinose, stachyose, inulin oligosaccharide, while being aided with high anti-oxidation green tea powder, and cooperate bifidobacterium lactis, plant cream
Bacillus, Lactobacillus rhamnosus and Lactobacillus salivarius compound probiotic have the function that reduce blood glucose, reach especially by following manner
To blood sugar reducing function:
(1) by beneficial flora in supplement, paraphyte, the proliferation of beneficial flora consumes glucose, fructose in enteron aisle
Deng, make enter sanguimotor sugar be greatly decreased, reach hypoglycemic purpose.
(2) by proliferation beneficial flora, optimize internal Tiny ecosystem, construct biology, chemistry, immune three big health in vivo
Protective barrier, effectively control blood glucose rise.
(3) optionally inhibit to decompose enzymatic activity, to inhibit the mistake because of blood glucose caused by taking in carbohydrate
It is fast to increase.
(4) high-quality dietary fiber forms gel filtration system in vivo, and delay glucose absorbs, and reduces body to pancreas islet
The requirement of element achievees the purpose that reduce blood glucose.
(5) by improving insulin sensitivity, " glucose is inhibited to operate Carriers Active ", inhibiting relevant enzymes in enteron aisle
Activity, the oxidative damage for reducing pancreaticβ-cell and the expression for lowering control gluconeogenesis gene.
The present invention it is resulting it is hypoglycemic with oligosaccharide probiotics solid beverage be faint yellow, slightly sweet band astringent taste, in uniform
It is powdered, hypoglycemic physical and chemical index and nutritive index with oligosaccharide probiotics solid beverage resulting to above embodiments 1 into
Row detection, specific testing result difference are as shown in table 1:
The hypoglycemic testing result with oligosaccharide probiotics solid beverage of table 1
| Inspection project | Detection method | Testing result |
| Ash content (g/100g) | The first method of GB 5009.4-2016 | 0.27 |
| Moisture (g/100g) | The first method of GB 5009.3-2016 | 1.76 |
| B. longum counts (CFU/g) | GB 4789.35-2016 | 3.4×108 |
| Lactic acid bacterial count (CFU/g) | GB 4789.35-2016 | 1.2×109 |
| Energy (KJ/100g) | GB 28050-2011 | 1655 |
| Protein (g/100g) | The first method of GB 5009.5-2016 | 0.60 |
| Fatty (g/100g) | The first method of GB 5009.6-2016 | <0.1 |
| Carbohydrate content (g/100g) | GB 28050-2011 | 96.17 |
| Total dietary fiber (g/100g) | GB 5009.88-2014 | 1.20 |
| Sodium (mg/100g) | The first method of GB 5009.91-2017 | 33.6 |
As shown in Table 1, the resulting hypoglycemic physical and chemical index and trophonemata with oligosaccharide probiotics solid beverage of the present invention
Mark is met the requirements of the standard, and the viable count of Bifidobacterium reaches 3.4 × 108CFU/g, viable count of lactobacillus reaches 1.2 ×
109CFU/g, viable count content are higher.
The resulting hypoglycemic eating method with oligosaccharide probiotics solid beverage of the present invention are as follows: the complex prebiotics of 18g
Solid beverage is a packet, it is daily in, taken after mixing it with water 1 packet with 40 DEG C of warm water below before dinner, or drinks are mixed takes with warm tea, coffee etc.,
The water Instant Drinks of 100-150mL are added when drinking in every packet.Above embodiments are resulting hypoglycemic with oligosaccharide probiotics
Solid beverage carries out clinical observation for 200 diabetic populations, wherein women number accounts for 30%, and male's number accounts for 70%；
60%, the 50-60 years old number that account for of 40-50 years old number accounts for 20%, and number accounts for 20% within 60 years old or more；There is the number of 1-3 medical history to account for
30%, there is the number of 4-7 medical history to account for 40%, the number of 10 years or more medical histories accounts for 30%.The result shows that the resulting drop of the present invention
Blood glucose with oligosaccharide probiotics solid beverage to the effective percentage of diabetic population up to 98% or more, and reducing insulin dosage
In the case of assist the edible present invention it is resulting it is hypoglycemic use oligosaccharide probiotics solid beverage, blood glucose reduces obvious；It is taken reducing
With assist in the case where hypoglycemic survival dose the edible present invention it is resulting it is hypoglycemic use oligosaccharide probiotics solid beverage, blood glucose reduces
Obviously；Postprandial glucose control accounts for 20% in the number of 6-7mmol/L, and number of the Postprandial glucose control in 7-10mmol/L accounts for
60%, fasting blood-glucose accounts for 20% in 6mmol/L number below.
The following are the clinical effectiveness of the hypoglycemic part typical case with oligosaccharide probiotics solid beverage of the present invention:
Case 1
Zhang, male, 45 years old, suffers from diabetes 5 years, 7~8mmol/L of fasting blood-glucose, 10~12mmol/L of postprandial blood sugar, passes through
The resulting hypoglycemic use oligosaccharide probiotics solid beverage of embodiment 1 is taken after 15 days, is often vented, Postprandial glucose control exists
5.1~8mmol/L.
Case 2
Mr. Luo, male, 62 years old, suffers from diabetes 10 years, 8~9mmol/L of fasting blood-glucose, 11~12mmol/L of postprandial blood sugar, warp
It crosses and takes the resulting hypoglycemic use oligosaccharide probiotics solid beverage of embodiment 2 after 15 days, be often vented, Postprandial glucose control exists
7.1~8.2mmol/L.
Case 3
Mr. Bai, female 42 years old, suffer from diabetes 7 years, and afternoon, fasting blood-glucose 17.1mmol/L, resulting by taking embodiment 1
Hypoglycemic after one hour, to be often vented with oligosaccharide probiotics solid beverage, Postprandial glucose control is in 16.2mmol/L, blood glucose drop
It is low obvious.
Case 4
Zhao, female 50 years old, suffer from diabetes 3 years, and mmol/L within 10 can just be dropped to by beating insulin, deactivate insulin now
Afterwards, resulting hypoglycemic with after oligosaccharide probiotics solid beverage 12 days by taking embodiment 1, Postprandial glucose control 8~
9mmol/L。
Hypoglycemic there is conspicuousness to change diabetes with oligosaccharide probiotics solid beverage in conclusion the present invention is resulting
Kind effect can partially replace the intervention of insulin and drug, the usage amount of drug be reduced, to the crowd in each diabetic history stage
It is helpful, to effect crowd's asexuality difference, diabetes can be assisted in the treatment of with composite medicine, in overall 15 days onset times.This
The internal how glycolytic factor can be prevented by inventing resulting hypoglycemic oligosaccharide probiotics solid beverage and containing, optionally
Inhibit the two carbohydrate-splitting enzymes activity such as invertase and maltose in small intestine, to inhibit because intake sucrose is (in small intestine invertase
Resolve into glucose and fructose under effect and be absorbed) caused by blood glucose rise；And insulin resistance can be improved, protect pancreas
Island cells play normal physiological function, to diabetes are reduced, maintains healthy physiological status to have in enhancing sugar tolerance effect
Significance.
Although the present invention is described in detail with a general description of the specific embodiments in this specification,
But on the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.
Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed model
It encloses.
Claims (8)
1. a kind of hypoglycemic use oligosaccharide probiotics solid beverage, which is characterized in that including following raw material: Oligomeric manna sugar is answered
Close probiotics, stachyose, L-arabinose, green tea powder and inulin.
2. hypoglycemic oligosaccharide probiotics solid beverage according to claim 1, which is characterized in that described compound prebiotic
Bacterium bag contains: bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius.
3. hypoglycemic oligosaccharide probiotics solid beverage according to claim 2, which is characterized in that the use of the raw material
Amount are as follows: 8.0-9.6 parts of Oligomeric manna sugar, 0.7-1.1 parts of compound probiotic, 17.0-18.2 parts of stachyose, L-arabinose
50.0-50.6 parts, 1.5-2.1 parts of green tea powder and 20.0-21.2 parts of inulin.
4. hypoglycemic oligosaccharide probiotics solid beverage according to claim 3, which is characterized in that the use of the raw material
Amount are as follows: 8.8 parts of Oligomeric manna sugar, 0.9 part of compound probiotic, 17.6 parts of stachyose, 50.3 parts of L-arabinose, green tea powder 1.8
Part and 20.6 parts of inulin.
5. hypoglycemic oligosaccharide probiotics solid beverage according to claim 3, which is characterized in that described compound prebiotic
Bacterium bag contains: 3-5 parts of bifidobacterium lactis, 3-5 parts of lactobacillus plantarum, 3-5 parts of Lactobacillus rhamnosus and 3-5 parts of Lactobacillus salivarius.
6. hypoglycemic oligosaccharide probiotics solid beverage according to claim 5, which is characterized in that described compound prebiotic
Bifidobacterium lactis in bacterium, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius mass ratio be 1:1:1:1.
7. a kind of hypoglycemic preparation method with oligosaccharide probiotics solid beverage, which is characterized in that including following preparation step:
Oligomeric manna sugar, compound probiotic, stachyose, L-arabinose, green tea powder and inulin are uniformly mixed, obtained hypoglycemic with oligomeric
Sugared probiotics solid beverage.
8. the hypoglycemic preparation method with oligosaccharide probiotics solid beverage according to claim 7, which is characterized in that institute
Stating compound probiotic includes: bifidobacterium lactis, lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus salivarius.
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| CN111165709A (en) * | 2020-02-27 | 2020-05-19 | 湖州中科锦肽生物科技有限公司 | Solid beverage with blood sugar control function and preparation method thereof |
| CN111357909A (en) * | 2020-04-02 | 2020-07-03 | 吉林农业科技学院 | Purification process and determination experimental method of mangosteen polysaccharide hypoglycemic solid beverage |
| CN112075638A (en) * | 2019-06-14 | 2020-12-15 | 丰华生物科技股份有限公司 | Food compositions and pharmaceutical compositions comprising a hypoglycemic lactic acid bacterial strain |
| CN114343097A (en) * | 2021-12-20 | 2022-04-15 | 江苏碧清园食品科技有限公司 | Probiotic solid beverage capable of assisting in reducing blood sugar and preparation method thereof |
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Application publication date: 20190118 |