CN109211992A - The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement - Google Patents

The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement Download PDF

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Publication number
CN109211992A
CN109211992A CN201710515826.5A CN201710515826A CN109211992A CN 109211992 A CN109211992 A CN 109211992A CN 201710515826 A CN201710515826 A CN 201710515826A CN 109211992 A CN109211992 A CN 109211992A
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electrode
layer
laid
coating
electrodes
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李岩
李国霞
章星
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Edan Instruments Inc
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Edan Instruments Inc
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Priority to CN201710515826.5A priority Critical patent/CN109211992A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

The invention discloses a kind of telegraph circuit plate for vim and vigour Biochemistry measurement and the methods for making electrode, and telegraph circuit plate includes: substrate layer, and substrate layer is circuit board;Multiple electrodes, multiple electrodes be arranged in the first side of substrate layer and respectively measuring electrode, to electrode and reference electrode;Each electrode includes multiple metal layers for stacking gradually laying;First coating, the first coating is covered in the first side of substrate layer and at least part of each electrode is exposed from the first coating;Multiple measurement points, multiple measurement points are arranged in the second side of substrate layer, and each measurement point includes multiple metal layers for stacking gradually laying;At least part of second coating, measurement point is exposed from the second coating.Wherein, circuit board is widely used in electronic product, is easy to obtain, the cost of material is low.In addition, the method based on circuit board making electrode is flexible, and of less demanding to technique.

Description

The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement
Technical field
The present invention relates to Biochemistry measurement technical field more particularly to a kind of telegraph circuit plate for vim and vigour Biochemistry measurement with And the method based on circuit board making electrode.
Background technique
At present there are mainly two types of vim and vigour Biochemistry measurement electrodes, one is the liquid soaked electrodes that large-scale instrument uses, separately One is solid state electrodes.Liquid soaked electrode volume is larger, it is difficult to be miniaturized, and use silicon base make electrode, to technique, Production environment is more demanding, at high cost.
Summary of the invention
The present invention is directed to solve at least some of the technical problems in related technologies.For this purpose, the present invention mentions A kind of telegraph circuit plate for vim and vigour Biochemistry measurement out, the circuit board is small in size, at low cost, easily fabricated.
The present invention further proposes a kind of method based on circuit board making electrode.
The circuit board of production electrode according to the present invention for vim and vigour Biochemistry measurement, substrate layer, the substrate layer is electricity Road plate;Multiple electrodes, the multiple electrode be arranged in the first side of the substrate layer and respectively measuring electrode, to electrode And reference electrode;Each electrode includes multiple metal layers for stacking gradually laying;First coating, first coating It is covered in the first side of the substrate layer and at least part of each electrode is exposed from first coating;It is more A measurement point, the multiple measurement point are arranged in the second side of the substrate layer, each measurement point include it is multiple according to The metal layer of secondary stack paving;Second coating, second coating is covered in the second side of the substrate layer and institute At least part for stating measurement point is exposed from second coating.
The circuit board of production electrode according to the present invention for vim and vigour Biochemistry measurement, circuit board are widely used in electronics production In product, it is easy to obtain, the cost of material is low, can significantly reduce the production cost of circuit board.In addition, the electrode based on circuit board making Production method is flexible, of less demanding to technique, so as to be conducive to produce in enormous quantities.
In some examples of the invention, multiple metal layers of the electrode and multiple metal layers of the measurement point wrap Include: copper sheet layer, the copper sheet layer are laid on the substrate layer;Nickel layer, the nickel layer are laid on the copper sheet layer;Layer gold, The layer gold is laid on the nickel layer.
In some examples of the invention, the layer gold in multiple metal layers of each electrode is two layers, described in two layers Layer gold is thin layer gold and thick layer gold, and the thin layer gold is laid between the nickel layer and the thick layer gold, the thickness of the thickness layer gold Degree be h1, the thin layer gold with a thickness of h2, wherein d1 > 1.2um, 0.05um < d2 < 0.075um;The measurement point it is more The layer gold in a metal layer is thin layer gold.
In some examples of the invention, the diameter of the thick layer gold to electrode is greater than the measuring electrode and institute State the diameter of the thick layer gold of reference electrode;The diameter of the copper sheet layer to electrode is corresponding greater than the measuring electrode The copper sheet layer diameter.
In some examples of the invention, first coating is multilayer and second coating is one layer.
In some examples of the invention, the first coating described in multilayer offers window corresponding with the electrode.
In some examples of the invention, the diameter of the window of the first coating described in multilayer is far from the substrate It is incremented by successively on the direction of layer.
It is in some examples of the invention, described to arrange to electrode, the measuring electrode and the reference electrode in two rows, The first row electrode is multiple measuring electrodes, and the second row electrode is described to electrode, the reference electrode and multiple surveys Measure electrode.
In some examples of the invention, the first row electrode is divided into the tip electrodes and target at both ends, adjacent The distance between two targets it is identical and be d1, between the tip electrodes and the adjacent target Distance is d2, wherein d2 > d1.
In some examples of the invention, the measuring electrode includes: impedance electrodes, galvanic electrode and voltage electrode, institute It is the impedance electrodes, the galvanic electrode and voltage electricity that measuring electrode, which is stated, in the distributing order that fluid path flows through on direction Pole, it is described to electrode between the galvanic electrode.
In some examples of the invention, the circuit board is printed circuit board.
Method according to the present invention based on production electrode on circuit board, comprising the following steps: selecting circuit plate is as base Plate layer;Be laid with multiple electrodes in the first side of the substrate layer, multiple electrodes be respectively measuring electrode, to electrode and Multiple metal layers of reference electrode, the electrode are successively laid with;The first coating is laid in the first side of the substrate layer And each electrode is exposed from first coating;Multiple measurements are laid in the second side of the substrate layer Multiple metal layers of point, the measurement point are successively laid with;It is laid with the second coating in the second side of the substrate layer and makes Each measurement point is obtained to expose from second coating.
Method according to the present invention based on production electrode on circuit board, it is of less demanding to technique, so as to be conducive to Produce in enormous quantities.And electrode and measurement point stable structure, reliable operation.
In some examples of the invention, multiple electrodes, multiple electricity are laid in the first side of the substrate layer Include: in the step of pole is respectively measuring electrode, to electrode and reference electrode, and multiple metal layers of the electrode are successively laid with It is laid with multiple copper sheet layers on the substrate layer, is laid with nickel layer respectively on the multiple copper sheet layer, divides on multiple nickel layers It is not laid with thin layer gold, is laid with thick layer gold respectively in multiple thin layer gold.
In some examples of the invention, multiple electrodes, multiple electricity are laid in the first side of the substrate layer Include: in the step of pole is respectively measuring electrode, to electrode and reference electrode, and multiple metal layers of the electrode are successively laid with by It is described to arrange to electrode, the measuring electrode and the reference electrode according to two rows, the multiple measurements of the first row electrode arrangements The tip electrodes for being located at both ends in the first row electrode are spaced apart with the target between two tip electrodes point by electrode Cloth, the distance between two adjacent described targets are identical and are d1, the tip electrodes and the adjacent intermediate electricity The distance between pole is d2, wherein d2 > d1, to electrode, the reference electrode and multiple described described in the second row electrode arrangements Measuring electrode.
In some examples of the invention, the measuring electrode includes: impedance electrodes, galvanic electrode and voltage electrode;? Multiple electrodes are laid in the first side of the substrate layer, multiple electrodes are respectively measuring electrode, to electrode and reference electricity It include: that the measuring electrode is flowed through into institute on direction in fluid path in the step of pole, multiple metal layers of the electrode are successively laid with Impedance electrodes, the galvanic electrode, the sequence to electrode, the galvanic electrode and the voltage electrode is stated to arrange.
Detailed description of the invention
Fig. 1 is the first side schematic diagram of telegraph circuit plate according to an embodiment of the present invention;
Fig. 2 is the second side schematic diagram of telegraph circuit plate according to an embodiment of the present invention;
Fig. 3 is the first side schematic diagram of telegraph circuit plate according to an embodiment of the present invention;
Fig. 4 is the cross-sectional view in the direction B-B along Fig. 3;
Fig. 5 is the enlarged drawing of region C in Fig. 4;
Fig. 6 is the enlarged drawing of region D in Fig. 4;
Fig. 7 is that the first side of substrate layer is equipped with the schematic diagram of electrode;
Fig. 8 is that the second side of substrate layer is equipped with the schematic diagram of measurement point;
Fig. 9 is the schematic diagram for being equipped with thick layer gold;
Figure 10 is the schematic diagram for being equipped with one layer of first coating;
Figure 11 is the schematic diagram for being equipped with two layers of first coatings;
Figure 12 is the enlarged drawing of region E in Figure 11;
Figure 13 is the schematic diagram for being equipped with three layer of first coating;
Figure 14 is the enlarged drawing of region F in Figure 13;
Figure 15 is the step flow chart according to an embodiment of the present invention based on the method for making electrode on circuit board.
Appended drawing reference:
Telegraph circuit plate 10;
Substrate layer 1;
Electrode 2;Measuring electrode 2a;To electrode 2b;Reference electrode 2c;Copper sheet layer 21;Nickel layer 22;Thin layer gold 23;Thick layer gold 24;
First coating 3;Window 31;
Measurement point 4a;Copper sheet layer 41;Nickel layer 42;Thin layer gold 43;
Second coating 5;
Conductive baseline 6.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings.Below with reference to The embodiment of attached drawing description is exemplary, it is intended to is used to explain the present invention, and is not considered as limiting the invention.
The telegraph circuit according to an embodiment of the present invention for vim and vigour Biochemistry measurement is described in detail below with reference to Fig. 1-Figure 14 Plate 10, the circuit board 10 can be applied in vim and vigour biochemical test card and in vim and vigour biochemical test instrument.
Telegraph circuit plate 10 according to an embodiment of the present invention for vim and vigour Biochemistry measurement may include: substrate layer 1, multiple Electrode 2, the first coating 3, multiple measurement point 4a and the second coating 5.
As shown in Figures 1 to 4, substrate layer 1 is circuit board, wherein circuit board is widely used in electronic product, is easy to obtain It takes, the cost of material is low, can significantly reduce the production cost of telegraph circuit plate 10.In addition, the method based on circuit board making electrode 2 Flexibly, of less demanding to technique, so as to be conducive to produce in enormous quantities.Optionally, circuit board can be printed circuit board.
Multiple electrodes 2 can be set in 1 first side of substrate layer, and multiple electrodes 2 are respectively measuring electrode 2a, to electrode 2b and reference electrode 2c, wherein measuring electrode 2a, to the quantity of electrode 2b and reference electrode 2c without limitation, for example, measurement electricity Pole 2a can be multiple, and measuring electrode 2a can be divided into galvanic electrode, voltage electrode and impedance electrodes.Measuring electrode 2a, Effect to electrode 2b and reference electrode 2c is the contents known of this field, is not described herein.In addition, multiple electrodes 2 are Chemical electrode, the ingredient of chemical electrode are the known content of this field, are not described herein.
Each electrode 2 includes multiple metal layers for stacking gradually laying, wherein the metal of multiple metal layers of electrode 2 can With difference, specifically, as shown in figure 5, electrode 2 includes: copper sheet layer 21, nickel layer 22 and layer gold, copper sheet layer 21 is laid on substrate layer 1 On, nickel layer 22 is laid on copper sheet layer 21, and layer gold is laid on nickel layer 22.Nickel layer 22 can be laid on copper by the way of plating On cortex 21, layer gold can be laid on nickel layer 22 by the way of plating.It, can be effective by the way that above-mentioned multiple metal layers are arranged The chemical component in electrode 2 is covered and protected, thereby may be ensured that the validity of electrode 2.
Further, layer gold is divided into two layers, and two layers of layer gold is thin layer gold 23 and thick layer gold 24, and thin layer gold 23 is laid on nickel layer Between 22 and thick layer gold 24.The electrode 2 of such setting conducts electricity very well, and 2 stability of electrode is good, and process of deployment is simple. Thick layer gold 24 with a thickness of h1, thin layer gold 23 with a thickness of h2, wherein d1 > 1.2um, 0.05um < d2 < 0.075um.
Wherein, as shown in figures 1 and 3, it arranges to electrode 2b, measuring electrode 2a and reference electrode 2c in two rows.Namely Say, multiple electrodes 2 are arranged in two rows, and such multiple electrodes 2 are reasonably distributed on substrate layer 1, so as to improve to electrode 2b, The reliability of measuring electrode 2a and reference electrode 2c, and avoid interfering with each other between adjacent electrode 2.
Specifically, as shown in figures 7 and 9, the first row electrode 2 is multiple measuring electrode 2a, and the second row electrode is to electrode 2b, reference electrode 2c and multiple measuring electrode 2a.The multiple electrodes being so distributed can make reference electrode 2c and to electrode 2b Position Design is reasonable, so as to improve the functional reliability of multiple electrodes 2.It is one to electrode 2b and reference electrode 2c.
In addition, as shown in fig. 7, tip electrodes and target that the first row electrode 2 divides for both ends, two adjacent centres The distance between electrode is identical and is d1, and the distance between tip electrodes and adjacent target are d2, wherein d2 > d1. It can be interfered with each other in this way to avoid the diffusion between measuring electrode 2a between constituent to avoid generation.
Wherein, when telegraph circuit plate 10 is mounted in vim and vigour biochemical test card, the first row measuring electrode 2a is placed in liquid The most downstream position on road, due to having fluid path in test card, liquid can flow through electrode 2, can prevent measuring electrode 2a's in this way Constituent is diffused into fluid path, pollutes the electrode 2 at fluid path rear.
The sequence that fluid path passes through electrode is HCT electrode (impedance electrodes), galvanic electrode, voltage electrode;Fluid path passes through first For measuring the HCT electrode of blood impedance, detected for real-time judge fluid path position and bubble;Then pass through galvanic electrode and electricity Piezoelectricity pole, two kinds of electrodes are flowed through in fluid path is separated arrangement on direction, so as to avoid galvanic electrode and voltage electrode It influences each other, signal stabilization can be improved.
Fluid path flows through on direction, and the left end electrode of the measuring electrode 2a of the second row is HCT electrode, and HCT electrode is located at fluid path Most upstream;To electrode 2b between galvanic electrode, that is, the second row electrode 2 distributing order on the direction that fluid path flows through is Impedance electrodes, galvanic electrode, to electrode and galvanic electrode.
Quantity positioned at the galvanic electrode to the two sides electrode 2b can be one or two.Optionally, the cloth of galvanic electrode The form of setting can be one, the left side, two, the right or two, the left side, one, the right.The connection and reasonable arrangement of galvanic electrode in this way, and Detection is accurate.
Optionally, as shown in fig. 7, the corresponding copper sheet of measuring electrode 2a can be greater than to the diameter of the copper sheet layer 21 of electrode 2b The diameter of layer 21.It can be conducive to improve the mark stability to electrode 2b in this way.
Optionally, as shown in fig. 7, the copper sheet layer 21 of reference electrode 2c is it is so structured that strip.It can be conducive in this way Improve the potential stability and consistency of reference electrode 2c.
Optionally, the thick layer gold 24 of measuring electrode 2a and reference electrode 2c is greater than to the diameter of the thick layer gold 24 of electrode 2b Diameter.Thus, it is possible to the setting reliability to electrode 2b be further improved, so as to convenient for the work to the electrode 2b later period Stability.
In addition, referring to figs. 1 and 2, to the projection of electrode 2b, measuring electrode 2a, reference electrode 2c on substrate layer 1 It is not overlapped, is connected between the two by via hole and conductive baseline 6, measurement point 4a is used with projection of the measurement point 4a on substrate layer 1 It is interconnected in apparatus measures probe, obtains electrode sensor signal.10 structure of circuit board of such setting is reliable, the operation is stable.
First coating 3 is covered in the first side of substrate layer 1, and at least part of each electrode 2 is from first Coating 3 exposes.That is, a part of each electrode 2 can be exposed from the first coating 3, so as to be convenient for electrode 2 Connection.
A specific embodiment according to the present invention, the first coating 3 can be multilayer, and the first coating 3 of multilayer can With the electrode 2 and other component of effective protection and fixing internal, so as to improve the structural reliability of circuit board 10.And it is more The material of first coating 3 of layer can be identical, for example, the first coating 3 of multilayer can be green oil.
Further, as shown in Figure 10-Figure 14, the first coating of multilayer 3 offers window 31 corresponding with electrode 2. Window 31 can expose from the first coating 3 in order to electrode 2, can be in order to the connection of electrode 2.
Specifically, as shown in Fig. 5 and Figure 12 and Figure 14, the diameter of the window 31 of the first coating of multilayer 3 is far from base It is incremented by successively on the direction of plate layer 1.Wherein the quantity of the first coating of multilayer 3 can be three layers.It is opened in this way by successively welding resistance Window can form boundary.When the material for preparing sensor is added to borderline region by mode for dispensing glue, the presence on boundary Dispensing consistency can be improved.Wherein, the window 31 of the first coating 3 of first layer can be less than the thick layer gold 24 in electrode 2 Diameter.
As shown in Figure 2 and Figure 8, measurement point 4a is multiple, and multiple measurement point 4a are arranged in the second side of substrate layer 1, Multiple measurement point 4a can be connected by via hole and conductive baseline 6 with electrode 2.Measurement point 4a includes multiple stacking gradually laying Metal layer.Wherein, the metal of multiple metal layers of measurement point 4a is different.Multiple metal layers of measurement point 4a include: copper sheet layer 41, nickel layer 42 and layer gold, copper sheet layer 41 are laid on substrate layer 1, and nickel layer 42 is laid on copper sheet layer 41, and layer gold is laid on nickel layer On 42.Specifically, layer gold can be thin layer gold 43.The thickness range of thin layer gold 43 can be with the thickness of the thin layer gold 23 of electrode 2 Range is identical.As a result, by the way that multiple metal layers are arranged, measurement point 4a stability can be made good, measurement is accurate.
Second coating 5 is covered in the second side of substrate layer 1, first side can be circuit board front, second Side can be the back side of circuit board.And at least part of measurement point 4a is exposed from the second coating 5.Second coating 5 It can play the role of protection and fixed measuring point 4a and other component.Wherein, optionally, the second coating 5 can be one layer. Second coating 5 can be green oil.
The method according to an embodiment of the present invention based on circuit board making electrode 2 is described in detail below with reference to Figure 15.
The manufacturing method of circuit board 10 the following steps are included: S1, selecting circuit plate as substrate layer 1.
S2, multiple electrodes 2 are laid in the first side of substrate layer 1, multiple metal layers of electrode 2 are successively laid with.Specifically Ground is laid with multiple copper sheet layers 21 on substrate layer 1, is laid with nickel layer 22 respectively on multiple copper sheet layers 21, on multiple nickel layers 22 It is laid with thin layer gold 23 respectively, is laid with thick layer gold 24 respectively in multiple thin layer gold 23.It, can be with by being successively laid with multiple metal layers Improve the stability and functional reliability of electrode 2.Wherein, measuring electrode 2a is greater than to the diameter of the electrode 2b copper sheet layer 21 being laid with The diameter of the copper sheet layer 21 of laying, can be improved the stability to electrode 2b in this way.
It is greater than the diameter for the thick layer gold 24 that measuring electrode 2a is laid with to the diameter of the electrode 2b thick layer gold 24 being laid with, in this way may be used To further improve the stability to electrode 2b.
In addition, being laid with two row copper sheet layers 21,21 pairs of the first row copper sheet layer on substrate layer 1 when being specifically laid with metal layer Answer multiple measuring electrode 2a, the second 21 pairs of row copper sheet layer reply electrode 2b, reference electrode 2c and multiple measuring electrode 2a.So may be used So that each 2 location arrangements of electrode are reasonable, reliable operation.
Specifically, it will arrange to electrode, measuring electrode and reference electrode according to two rows, the first row electrode 2 is arranged multiple surveys Electrode is measured, by the tip electrodes for being located at both ends in the first row electrode 2 and the target interval between two tip electrodes Distribution is opened, the distance between two adjacent targets are identical and are d1, between tip electrodes and adjacent target Distance is d2, wherein d2 > d1, the second row electrode arrangements are to electrode, reference electrode and multiple measuring electrodes.
Concrete operations can be such that the distance between the first row copper sheet layer 21 of laying difference, and the first row copper sheet layer 21 points of end copper sheet layer 21, intermediate copper sheet layers 21 for both ends, the laying of intermediate copper sheet layer 21 is apart from identical, end copper sheet layer 21 It is greater than the laying distance between intermediate copper sheet layer 21 with the laying distance of adjacent intermediate copper sheet layer 21.
In addition, measuring electrode is flowed through impedance electrodes on direction, galvanic electrode, to electrode, galvanic electrode and electricity in fluid path The sequence of piezoelectricity pole is arranged.
S3, it is laid with the first coating 3 in the first side of substrate layer 1, and makes each electrode 2 from the first coating 3 expose.First coating 3 can play the role of guard electrode 2 and other component.Optionally, in the first side of substrate layer 1 The first coating of upper laying multilayer 3, for example, three layers.First coating 3 can be green oil.Moreover, in each first coating 3 Uplifting window is to correspond to multiple electrodes 2.Turn on window can open a window for welding resistance, in this way can in order to the formation on boundary, so as to Convenient for the connection of electrode 2.Specifically, the diameter of the windowing of multiple first coatings 3 is incremented by the direction far from substrate layer 1.
S4, multiple measurement point 4a are laid in the second side of substrate layer 1, multiple metal layers of measurement point 4a are successively spread If.Specifically, it is laid with multiple copper sheet layers 41 on substrate layer 1, nickel layer 42 is laid with respectively on multiple copper sheet layers 41, in multiple nickel It is laid with thin layer gold 43 respectively on layer 42.By the way that multiple metal layers are arranged, measurement point 4a stable structure can be made, measurement is accurate.
S5, it is laid with the second coating 5 in the second side of substrate layer 1 and makes each measurement point 4a from the second coating 5 expose.Second coating 5 can play the role of protection and fixed measuring point 4a, and the second coating 5 can be green oil, such as Fig. 6 Shown, the second coating 5 can be one layer.
Method according to an embodiment of the present invention based on circuit board making electrode 2 as a result, it is of less demanding to technique, thus It can be conducive to produce in enormous quantities.And electrode 2 and measurement point 4a stable structure, reliable operation.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned Embodiment is changed, modifies, replacement and variant.

Claims (15)

1. a kind of telegraph circuit plate for vim and vigour Biochemistry measurement characterized by comprising
Substrate layer, the substrate layer are circuit board;
Multiple electrodes, the multiple electrode be arranged in the first side of the substrate layer and respectively measuring electrode, to electrode And reference electrode;Each electrode includes multiple metal layers for stacking gradually laying;
First coating, first coating be covered in the first side of the substrate layer and each electrode at least A part is exposed from first coating;
Multiple measurement points, the multiple measurement point are arranged in the second side of the substrate layer, and each measurement point includes Multiple metal layers for stacking gradually laying;
Second coating, second coating be covered in the second side of the substrate layer and the measurement point at least one Expose from second coating part.
2. telegraph circuit plate according to claim 1, which is characterized in that multiple metal layers of the electrode and the measurement Point multiple metal layers include:
Copper sheet layer, the copper sheet layer are laid on the substrate layer;
Nickel layer, the nickel layer are laid on the copper sheet layer;
Layer gold, the layer gold are laid on the nickel layer.
3. telegraph circuit plate according to claim 2, which is characterized in that the gold in multiple metal layers of each electrode Layer is two layers, and two layers layer gold is thin layer gold and thick layer gold, the thin layer gold be laid on the nickel layer and the thick layer gold it Between, the thickness layer gold with a thickness of h1, the thin layer gold with a thickness of h2, wherein d1 > 1.2um, 0.05um < d2 < 0.075um;
The layer gold in multiple metal layers of the measurement point is thin layer gold.
4. telegraph circuit plate according to claim 3, which is characterized in that the diameter of the thick layer gold to electrode is big In the diameter of the measuring electrode and the thick layer gold of the reference electrode;
The diameter of the copper sheet layer to electrode is greater than the diameter of the corresponding copper sheet layer of the measuring electrode.
5. telegraph circuit plate according to claim 1, which is characterized in that first coating is multilayer and described second Coating is one layer.
6. telegraph circuit plate according to claim 5, which is characterized in that the first coating described in multilayer offers and institute State the corresponding window of electrode.
7. telegraph circuit plate according to claim 6, which is characterized in that the window of the first coating described in multilayer Diameter is incremented by successively on the direction far from the substrate layer.
8. telegraph circuit plate according to claim 1, which is characterized in that described to electrode, the measuring electrode and described Reference electrode is arranged in two rows, and the first row electrode is multiple measuring electrodes, and the second row electrode is described to electrode, the ginseng Than electrode and multiple measuring electrodes.
9. telegraph circuit plate according to claim 8, which is characterized in that the first row electrode is divided into the end electricity at both ends Pole and target, the distance between two adjacent described targets are identical and are d1, tip electrodes and adjacent The distance between described target is d2, wherein d2 > d1.
10. telegraph circuit plate according to claim 8, which is characterized in that the measuring electrode includes: impedance electrodes, electricity Galvanic electricity pole and voltage electrode, it is the impedance electrodes, the electricity that the measuring electrode, which flows through the distributing order on direction in fluid path, Galvanic electricity pole and the voltage electrode, it is described to electrode between the galvanic electrode.
11. telegraph circuit plate according to claim 1, which is characterized in that the circuit board is printed circuit board.
12. a kind of method based on circuit board making electrode, which comprises the following steps:
Selecting circuit plate is as substrate layer;
Be laid with multiple electrodes in the first side of the substrate layer, multiple electrodes be respectively measuring electrode, to electrode and Multiple metal layers of reference electrode, the electrode are successively laid with;
It is laid with the first coating in the first side of the substrate layer and makes each electrode from first coating Expose;
Multiple measurement points are laid in the second side of the substrate layer, multiple metal layers of the measurement point are successively laid with;
It is laid with the second coating in the second side of the substrate layer and makes each measurement point from second covering Layer exposes.
13. the method according to claim 12 based on circuit board making electrode, which is characterized in that in the substrate layer It is laid with multiple electrodes in first side, multiple electrodes are respectively measuring electrode, to electrode and reference electrode, the electrode Include: in the step of multiple metal layers are successively laid with
It is laid with multiple copper sheet layers on the substrate layer, is laid with nickel layer respectively on the multiple copper sheet layer, in multiple nickel Thin layer gold is laid on layer respectively, is laid with thick layer gold respectively in multiple thin layer gold.
14. the method according to claim 12 based on circuit board making electrode, which is characterized in that
Be laid with multiple electrodes in the first side of the substrate layer, multiple electrodes be respectively measuring electrode, to electrode and Include: in the step of reference electrode, multiple metal layers of the electrode are successively laid with
It arranges described to electrode, the measuring electrode and the reference electrode according to two rows, the multiple institutes of the first row electrode arrangements Measuring electrode is stated, will be located between the tip electrodes and target between two tip electrodes at both ends in the first row electrode Spaced, the distance between two adjacent described targets are identical and are d1, the tip electrodes with it is adjacent described The distance between target is d2, wherein d2 > d1, to electrode, the reference electrode and more described in the second row electrode arrangements A measuring electrode.
15. the method according to claim 14 based on circuit board making electrode, which is characterized in that the measuring electrode packet It includes: impedance electrodes, galvanic electrode and voltage electrode;
Be laid with multiple electrodes in the first side of the substrate layer, multiple electrodes be respectively measuring electrode, to electrode and Include: in the step of reference electrode, multiple metal layers of the electrode are successively laid with
The measuring electrode is flowed through into impedance electrodes on the direction, galvanic electrode, described to electrode, the electricity in fluid path The arrangement of the sequence of galvanic electricity pole and the voltage electrode.
CN201710515826.5A 2017-06-29 2017-06-29 The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement Pending CN109211992A (en)

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CN201710515826.5A CN109211992A (en) 2017-06-29 2017-06-29 The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710515826.5A CN109211992A (en) 2017-06-29 2017-06-29 The method of telegraph circuit plate and production electrode for vim and vigour Biochemistry measurement

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Publication Number Publication Date
CN109211992A true CN109211992A (en) 2019-01-15

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CN114354714B (en) * 2022-01-07 2022-09-13 海南德名声科技有限责任公司 Micro-fluidic chip of blood gas analyzer and application

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