CN109199464B - Biopsy device for multi-chamber sample holder - Google Patents
Biopsy device for multi-chamber sample holder Download PDFInfo
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- CN109199464B CN109199464B CN201811287294.5A CN201811287294A CN109199464B CN 109199464 B CN109199464 B CN 109199464B CN 201811287294 A CN201811287294 A CN 201811287294A CN 109199464 B CN109199464 B CN 109199464B
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- sample holder
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- biopsy device
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- 238000001574 biopsy Methods 0.000 title claims abstract description 36
- 238000007789 sealing Methods 0.000 claims description 8
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 description 15
- 210000004872 soft tissue Anatomy 0.000 description 13
- 230000007246 mechanism Effects 0.000 description 12
- 238000005070 sampling Methods 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 7
- 238000001727 in vivo Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a biopsy device, comprising: a handle; the cutter comprises an outer cutter tube and an inner cutter tube, the rear end of the outer cutter tube is fixed on the handle, and the inner cutter tube is arranged in the outer cutter tube and can rotate relative to the outer cutter tube and axially reciprocate; a sample holder disposed within the handle, the sample holder having a plurality of sample chambers and a plurality of inlets in communication with the plurality of sample chambers, respectively; further comprises: the input catheter is arranged in the handle and can rotate around the rotation axis, the head end of the input catheter is communicated with the rear end of the inner cutter tube, and the tail end of the input catheter is selectively communicated with the inlet of one of the sample chambers when the input catheter rotates; and an input catheter driving device for driving the input catheter to rotate. The rotating part of the biopsy device is an input catheter, which has light weight, small power, low cost and high reliability.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a biopsy device of a multi-cavity sample holder.
Background
Biopsy devices are used to sample soft tissue in a patient in vivo. Biopsy devices typically include a handle and a cutter mounted to the handle. The cutter comprises an inner cutter tube and an outer cutter tube sleeved outside the inner cutter tube, a sampling groove is formed in the front end of the outer cutter tube along the radial direction, soft tissues are sucked into the sampling groove under the action of negative pressure after the outer cutter tube is punctured into the epidermis, and at the moment, the inner cutter tube rotates forwards to cut the soft tissues and hold the soft tissues at the front end of the inner cutter tube. The handle includes, in addition to a drive mechanism for driving the rotary cutting movement of the inner cutter tube, a sample holder into which soft tissue is drawn for temporary storage after the inner cutter tube of the cutter has acquired the soft tissue.
The earliest biopsy devices were provided with only a single chamber sample holder in which the tissue samples were mixed and indistinguishable. To address this problem, there are biopsy devices that divide the sample holder into a plurality of chamber units, and the sample holder is rotatable within the handle, the sample holder rotating to collect soft tissue into each chamber unit separately. The biopsy device adopts the mode of driving the whole sample holder to rotate, and because the sample holder has large gravity and soft tissues are stored, the biopsy device needs very large driving force, is easy to destroy the shape of the soft tissues, has high cost, and has poor accuracy of controllable rotation angle and low reliability.
Disclosure of Invention
In view of the above state of the art, the present invention provides a biopsy device for a multi-chamber sample holder that is low in cost, free from damage to soft tissue morphology, and has a controllable rotation angle and high accuracy.
In order to solve the above technical problems, the present invention provides a biopsy device of a multi-chamber sample holder, comprising: a handle; the cutter comprises an outer cutter tube and an inner cutter tube, the rear end of the outer cutter tube is fixed on the handle, and the inner cutter tube is arranged in the outer cutter tube and can rotate relative to the outer cutter tube and axially reciprocate; a sample holder disposed within the handle, the sample holder having a plurality of sample chambers and a plurality of inlets in communication with the plurality of sample chambers, respectively; further comprises: an input conduit disposed within the handle and rotatable about an axis of rotation, a leading end of the input conduit being in communication with a trailing end of the inner cutter tube, a trailing end of the input conduit being selectively in communication with an inlet of one of the sample chambers when the input conduit is rotated; and an input catheter driving device for driving the input catheter to rotate.
In the biopsy device of the multi-chamber sample holder, the input catheter is controlled to rotate by the input catheter driving device, and the inner cutter tube is selectively communicated with the inlet of one of the sample chambers, so that tissue samples sampled multiple times are stored in different chambers to be distinguished. The rotating part of the biopsy device is an input catheter, which has light weight, small power, low cost and high reliability.
In one embodiment, the head end of the input conduit is communicated with the rear end of the inner cutter tube through a first connecting component, and the tail end of the input conduit is connected with the inlets of a plurality of sample chambers through a second connecting component and selectively communicated with one inlet.
In one embodiment, the rotational axis of the input conduit coincides with the axis of the inner cutter tube, and the inlets of the plurality of sample chambers are arranged at intervals in the circumferential direction centering on the rotational axis.
In one embodiment, the tail end of the first connecting component is fixedly connected with the head end of the input catheter, the head end of the first connecting component is movably connected with the rear end of the inner cutter tube, and the first connecting component rotates along with the rotation of the input catheter; the rear end of the inner cutter tube is rotatable and axially reciprocable relative to the first coupling assembly.
In one embodiment, the first connection assembly comprises an outer sleeve and a sealing member, the outer sleeve is coaxial with the inner cutter tube, the tail end of the outer sleeve is fixedly connected with the head end of the input catheter, the rear end of the inner cutter tube is inserted into the head end of the outer sleeve and can rotate relative to the outer sleeve and axially reciprocate, and the sealing member is arranged between the rear end of the inner cutter tube and the outer sleeve.
In one embodiment, the outer sleeve further comprises an annular piston fixedly sleeved on the rear end of the inner cutter tube within the outer sleeve, and the seal is sleeved on the piston.
In one embodiment, the input conduit is Z-shaped, and the input conduit includes a first section, a second section, and a third section connected in sequence from a head end to a tail end of the input conduit.
In one embodiment, the sample holder comprises a cylindrical sample holder body, an annular chute is arranged on the end face of the first end of the sample holder body, the inlets of a plurality of sample chambers are positioned on the bottom surface of the chute, and the second connecting component comprises a sliding head, one end of the sliding head is connected with the tail end of the input conduit, and the other end of the sliding head is positioned in the chute and can slide along the chute.
In one embodiment, the sample holder further comprises a cover plate for sealing the slot of the chute, the cover plate being rotatably connected to the first end of the sample holder body, the cover plate being provided with a through hole for the input conduit to pass through.
In one embodiment, a plurality of outlets are provided on an end face of the second end of the sample holder body, the plurality of outlets being in communication with the plurality of sample chambers, respectively, the sample holder further comprising a plurality of drawer sample slots receivable within the plurality of sample chambers, respectively, the drawer sample slots being placed into or removed from the sample chambers through the outlets.
In one embodiment, an annular outlet is provided at a position of the housing of the handle corresponding to the outlet, and an annular buckle cover for opening and closing the outlet is provided at the outlet.
In one embodiment, the sample holder further comprises a vacuum suction tube comprising a main tube and a plurality of branch tubes, one ends of the plurality of branch tubes are respectively communicated with the plurality of sample chambers, and the other ends are communicated with the main tube.
In one embodiment, the input catheter driving device comprises a stepping motor and a first gear transmission mechanism, wherein the input end of the first gear transmission mechanism is in transmission connection with the output shaft of the stepping motor, and the output end of the first gear transmission mechanism is in transmission connection with the input catheter.
In one embodiment, the stepper motor is disposed in the rear end of the handle, and the output shaft of the stepper motor faces the front end of the handle and is parallel to the rotation axis, the first gear transmission mechanism comprises a third gear, a fourth gear, a fifth gear and a sixth gear, the third gear is mounted on the output shaft of the stepper motor, the fourth gear and the fifth gear are coaxially mounted on the rotation shaft, the fourth gear is meshed with the third gear, the sixth gear is sleeved on the input conduit, and the sixth gear is meshed with the fifth gear.
The advantageous effects of the additional technical features of the present invention will be described in the detailed description section of the present specification.
Drawings
FIG. 1 is a partial cross-sectional view of a biopsy device of a multi-chamber sample holder in an embodiment of the invention;
FIG. 2 is a partial cross-sectional view of a tool in an embodiment of the invention;
FIG. 3 is a cross-sectional view of a handle in an embodiment of the invention;
FIG. 4 is a cross-sectional view of a handle in an embodiment of the invention;
fig. 5 and 6 are cross-sectional views of a first connecting assembly according to an embodiment of the present invention, wherein fig. 5 is a state in which the inner cutter tube moves to a front end point of a movement stroke, and fig. 6 is a state in which the inner cutter tube moves to a rear end point of the movement stroke;
FIG. 7 is a cross-sectional view of a sample holder in an embodiment of the invention;
FIG. 8 is a left side view of a sample holder of an embodiment of the present invention with a cover plate removed;
fig. 9 is a right side view of a sample holder with a cover plate removed in an embodiment of the invention.
Reference numerals illustrate: 10. a handle; 11. a housing; 111. an annular buckle cover; 12. a cutter driving device; 121. a driving motor; 122. a first gear; 123. a second gear; 124. a screw sleeve; 13. an input catheter drive device; 131. a stepping motor; 132. a third gear; 133. a fourth gear; 134. a fifth gear; 135. a sixth gear; 20. a cutter; 21. an outer cutter tube; 211. a puncture needle; 212. a sampling groove; 22. an inner cutter tube; 30. a sample holder body; 31. a sample chamber; 32. a chute; 33. an inlet; 34. the drawer is shaped like a sample groove; 35. a first end; 36. a second end; 37. a central bore; 40. an input conduit; 41. a first section; 42. a second section; 43. a third section; 50. a first connection assembly; 51. an outer sleeve; 511. a small diameter section; 512. flanging; 52. a piston; 53. a seal; 60. a second connection assembly; 61. a slider; 62. a cover plate; 70. a vacuum suction tube; 71. a main pipe; 72. and a branch pipe.
Detailed Description
The invention will be described in detail below with reference to the drawings in conjunction with embodiments. The following embodiments and features in the embodiments may be combined with each other without collision.
The biopsy device of the multi-chamber sample holder of the present invention is used for in vivo sampling of soft tissue within a patient. As shown in FIG. 1, the biopsy device in one embodiment of the present invention includes a handle 10, a cutter 20, a sample holder, and an input catheter 40. The handle 10 includes a housing 11, a cutter driving device 12, an input catheter driving device 13, and a control circuit board (not shown), wherein the housing 11 is a bar shape for being held by a hand, and the cutter driving device 12, the input catheter driving device 13, and the control circuit board are accommodated in the housing 11.
As shown in fig. 2, the cutter 20 in the present embodiment includes an outer cutter tube 21 and an inner cutter tube 22, a puncture needle 211 is provided at the front end of the outer cutter tube 21, a sampling groove 212 is provided in the radial direction at a position near the front end of the outer cutter tube 21, and the rear end of the outer cutter tube 21 is fixedly installed in the front end of the housing 11. An inner cutter tube 22 is provided inside the outer cutter tube 21, and is rotatable and axially reciprocable with respect to the outer cutter tube 21. The front end of the inner cutter tube 22 has a cutter head for cutting tissue passing through the sampling slot 212, and the rear end of the inner cutter tube 22 is inserted into the housing 11 and connected to the cutter driving device 12. When the cutter driving device 12 drives the inner cutter tube 22 to rotate and axially reciprocate, the cutter head of the inner cutter tube 22 and the sampling slot 212 perform relative shearing movement, so that the cutter head can cut the tissue entering the sampling slot 212.
As shown in fig. 1 and 3, the tool driving device 12 in this embodiment includes a driving motor 121, a second gear transmission mechanism and a screw sleeve 124, and the second gear transmission mechanism includes, as an example, a first gear 122 and a second gear 123, the first gear 122 is mounted on an output shaft of the driving motor 121, the second gear 123 is meshed with the first gear 122, the second gear 123 is sleeved on the screw sleeve 124, and the screw sleeve 124 is sleeved on a rear end of the inner cutter tube 22. When the driving motor 121 works, the first gear 122 rotates, the first gear 122 drives the second gear 123 to rotate, the screw sleeve 124 rotates, threads matched with the screw sleeve 124 are formed on the rear section, close to the rear end, of the inner cutter tube 22, and accordingly the inner cutter tube 22 can rotate and axially reciprocate.
Referring to fig. 1 and 7, the sample holder is provided in the housing 11, and includes a sample holder body 30, the sample holder body 30 having a first end 35 near the inner cutter tube 22 side and a second end 36 opposite to the first end 35, a plurality of sample chambers 31 for temporarily storing soft tissues being provided on the sample holder body 30, a plurality of inlets 33 respectively communicating with the plurality of sample chambers 31 being provided on an end face of the first end 35 of the sample holder body 30, the plurality of inlets 33 being arranged at intervals in a circumferential direction.
The input conduit 40 is arranged within said handle 10 and is rotatable about an axis of rotation L, preferably the axis of rotation L of the input conduit 40 coincides with the axis of the inner cutter tube 22. The leading end of the input conduit 40 is connected to the rear end of the inner cutter tube 22 via a first connection assembly 50, and the trailing end of the input conduit 40 is connected to the inlets 33 of the plurality of sample chambers 31 via a second connection assembly 60. As shown in fig. 4, the input conduit 40 in the embodiment is Z-shaped, and includes a first section 41, a second section 42, and a third section 43 sequentially connected from the head end to the tail end of the input conduit 40.
The input duct driving device 13 is used for driving the input duct 40 to rotate. As shown in fig. 1 and 3, the input catheter driving device 13 includes a stepper motor 131 and a first gear transmission mechanism, an input end of the first gear transmission mechanism is in transmission connection with an output shaft of the stepper motor 131, and an output end of the first gear transmission mechanism is in transmission connection with the input catheter 40. As an example, the stepping motor 131 in the present embodiment is provided in the rear end of the housing 11 of the handle 10, and the output shaft of the stepping motor 131 is directed toward the front end of the housing 11 and parallel to the rotation axis L. The first gear transmission mechanism in this embodiment includes a third gear 132, a fourth gear 133, a fifth gear 134, and a sixth gear 135, the third gear 132 is mounted on the output shaft of the stepping motor 131, the fourth gear 133 and the fifth gear 134 are coaxially mounted on the rotating shaft, rotated synchronously, the fourth gear 133 is engaged with the third gear 132, the sixth gear 135 is mounted on the first section 41 of the input duct 40, and the sixth gear 135 is engaged with the fifth gear 134. When the stepper motor 131 works, according to the command input by the host, the preset angle is rotated to drive the third gear 132 to rotate, then drive the fourth gear 133 to rotate, then drive the fifth gear 134 to rotate, then drive the sixth gear 135 to rotate, and finally the input conduit 40 rotates for a preset angle to align with the inlet 33 of each sample chamber 31. The input conduit driving device 13 in this embodiment adopts a stepper motor as a power source, and the rotation angle of the stepper motor has high precision, which is beneficial to precisely controlling the rotation angle of the input conduit 40. In addition, the first gear transmission mechanism adopts the structure, and has the advantage of compact structure so as to save space.
The biopsy device of the multi-chamber sample holder of the present invention selectively communicates the inner cutter tube 22 with the inlet 33 of one of the sample chambers 31 by controlling the rotation of the input catheter 40 by the input catheter driving device 13, thereby storing the tissue samples sampled multiple times in different chambers to be distinguished. The rotating component of the biopsy device is the input catheter 40, which is lightweight, requires little power, is low cost, and is highly reliable.
As shown in fig. 5 and 6, as an example, the tail end of the first connection assembly 50 is fixedly connected to the head end of the input catheter 40, the head end of the first connection assembly 50 is movably connected to the rear end of the inner cutter tube 22, the first connection assembly 50 rotates with the rotation of the input catheter 40, and the rear end of the inner cutter tube 22 is rotatable and axially reciprocable with respect to the first connection assembly 50. As one example, the first connection assembly 50 includes an outer sleeve 51 and a sealing member 53, the outer sleeve 51 is coaxial with the inner cutter tube 22, and a tail end of the outer sleeve 51 is fixedly connected with a head end of the input catheter 40. Specifically, the rear end of the outer sleeve 51 forms an outward small diameter section 511, and the head end of the input catheter 40 is inserted into the small diameter section 511 at the tail end of the outer sleeve 51 and is tightly matched with the small diameter section 511, and the head end of the input catheter 40 is formed with a chamfer to avoid blockage. Further alternatively, the inner wall between the small diameter section 511 and the outer sleeve 51 is smoothly transitioned or chamfered. The front end of the outer sleeve 51 is formed with an inward flange 512, the rear end of the inner cutter tube 22 is inserted into the front end of the outer sleeve 51 and is rotatable relative to the outer sleeve 51 and axially reciprocable, and the seal 53 is disposed between the rear end of the inner cutter tube 22 and the outer sleeve 51. Preferably, the outer sleeve 51 further includes an annular piston 52, the piston 52 is fixedly sleeved on the rear end of the inner cutter tube 22 positioned in the outer sleeve 51, and the outer diameter of the piston 52 is larger than the inner diameter of the flange 512, so that the inner cutter tube 22 cannot fall off from the outer sleeve 51 during axial reciprocation. The sealing member 53 is sleeved on the piston 52, and prevents tissue fluid from leaking out of the front end of the outer sleeve 51.
As shown in fig. 7-9, the sample holder body 30 is preferably in the shape of a hollow cylinder, the central axis of the sample holder body 30 coincides with the rotation axis L, and the plurality of inlets 33 are arranged at intervals in the circumferential direction centering around the central axis of the sample holder body 30. Further preferably, a plurality of said sample chambers 31 are arranged at intervals in a circumferential direction centered on a central axis of said sample holder body 30, said sample chambers 31 extending from said first end 35 to said second end 36.
Preferably, an annular chute 32 is provided on the end face of the first end 35 of the sample holder body 30, the inlets 33 of the plurality of sample chambers 31 are located on the bottom surface of the chute 32, and the second connecting assembly 60 includes a sliding head 61, one end of the sliding head 61 is connected to the tail end of the input conduit 40, and the other end is located in the chute 32 and can slide along the chute 32. The rotation of the input conduit 40 is guided by the chute 32 and the slider 61.
Preferably, the sample holder further comprises a cover plate 62 for sealing the notch of the chute 32, the cover plate 62 being rotatably connected to the first end 35 of the sample holder body 30, the rotation axis L of the cover plate 62 coinciding with the central axis of the sample holder body 30, the cover plate 62 being provided with a through hole for the input conduit 40 to pass through. The cover plate 62 seals the notch of the chute 32, prevents the liquid such as blood water from flowing out of the notch when the sliding head 61 is misaligned with the inlet 33, and solves the sealing problem of the vacuum environment of the chamber.
Preferably, a plurality of outlets are provided on an end face of the second end 36 of the sample holder body 30, the plurality of outlets being in communication with a plurality of the sample chambers 31, respectively. The sample holder body 30 further comprises a plurality of drawer sample slots 34 receivable within a plurality of the sample chambers 31, respectively, the drawer sample slots 34 being placed into the sample chambers 31 or removed from the sample chambers 31 through outlets. The end of the drawer type sample groove 34 is provided with a handle, and the drawer type sample groove 34 can be inserted and pulled through the push-pull handle, so that samples can be taken out conveniently. Preferably, the housing 11 of the handle 10 is provided with an annular outlet and an annular cover 111 (see fig. 1) for opening and closing the outlet at a position corresponding to the outlet, and the annular cover 111 is uncovered from the rear of the handle 10 so that the handle can be pushed and pulled to take out the sample.
In one embodiment, the sample holder further comprises a vacuum suction tube 70, said vacuum suction tube 70 comprising a main tube 71 and a plurality of branch tubes 72, one end of each of said plurality of branch tubes 72 being in communication with a plurality of said sample chambers 31, and the other end being in communication with said main tube 71. Preferably, a central hole 37 penetrating in the axial direction is provided in the center of the sample holder body 30, the main pipe is located in the central hole 37 and extends in the axial direction of the central hole 37, and a plurality of the branch pipes are located in the central hole 37 and extend in the radial direction of the central hole 37. In use of the biopsy device, the main tube 71 is connected to an external negative pressure system, and suction is provided by the negative pressure system to suck the soft tissue cut by the cutter 20 into the sample chamber 31.
In summary, the biopsy device of the present invention selectively communicates the inner cutter tube 22 with the inlet 33 of one of the sample chambers 31 by controlling the rotation of the input catheter 40 by the input catheter driving device 13, so as to store the tissue samples sampled multiple times in different chambers for differentiation. The rotating component of the biopsy device is the input catheter 40, which is lightweight, requires little power, is low cost, and is highly reliable.
The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention.
Claims (13)
1. A biopsy device for a multi-chamber sample holder, comprising:
a handle;
the cutter comprises an outer cutter tube and an inner cutter tube, the rear end of the outer cutter tube is fixed on the handle, and the inner cutter tube is arranged in the outer cutter tube and can rotate relative to the outer cutter tube and axially reciprocate;
a sample holder disposed within the handle, the sample holder having a plurality of sample chambers and a plurality of inlets in communication with the plurality of sample chambers, respectively;
characterized by further comprising:
the input catheter is arranged in the handle and can rotate around the rotation axis, the head end of the input catheter is communicated with the rear end of the inner cutter tube, the tail end of the input catheter is selectively communicated with the inlet of one of the sample chambers when the input catheter rotates, the input catheter is Z-shaped, and the input catheter comprises a first section, a second section and a third section which are sequentially connected from the head end to the tail end of the input catheter; and
and the input catheter driving device is used for driving the input catheter to rotate.
2. The multi-chamber sample holder biopsy device of claim 1, wherein a leading end of the input conduit communicates with a trailing end of the inner cutter tube via a first connection assembly, and a trailing end of the input conduit communicates with inlets of a plurality of the sample chambers via a second connection assembly and selectively with one of the inlets.
3. The multi-chamber sample holder biopsy device of claim 2, wherein the axis of rotation of the input conduit coincides with the axis of the inner cutter tube, wherein the inlets of the plurality of sample chambers are circumferentially spaced about the axis of rotation.
4. A multi-chamber sample holder biopsy device according to claim 3, wherein the trailing end of the first coupling assembly is fixedly coupled to the leading end of the input conduit, the first coupling assembly being rotatable with rotation of the input conduit; the front end of the first connecting component is movably connected with the rear end of the inner cutter tube, and the rear end of the inner cutter tube can rotate relative to the first connecting component and axially reciprocate.
5. The multi-chamber sample holder biopsy device of claim 4, wherein the first coupling assembly comprises an outer cannula coaxial with the inner cutter tube, a trailing end of the outer cannula fixedly coupled to a leading end of the input conduit, a trailing end of the inner cutter tube inserted into the leading end of the outer cannula and rotatable and axially reciprocable relative to the outer cannula, and a seal disposed between the trailing end of the inner cutter tube and the outer cannula.
6. The multi-chamber sample holder biopsy device of claim 5, wherein the outer sleeve further comprises an annular piston fixedly sleeved on a rear end of the inner cutter tube within the outer sleeve, the seal being sleeved on the piston.
7. A multi-chamber sample holder biopsy device according to claim 3, wherein the sample holder comprises a cylindrical sample holder body with an annular chute provided on an end face of a first end of the sample holder body, the inlets of a plurality of the sample chambers being located on a bottom surface of the chute, the second connection assembly comprising a slider head having one end connected to a trailing end of the input conduit and the other end located within and slidable along the chute.
8. The biopsy device of claim 7, further comprising a cover plate for sealing the slot of the chute, the cover plate rotatably coupled to the first end of the sample holder body, the cover plate having a throughbore disposed therethrough for the input conduit.
9. The multi-chamber sample holder biopsy device of claim 7, wherein a plurality of outlets are provided on an end face of the second end of the sample holder body, the plurality of outlets being in communication with a plurality of the sample chambers, respectively, the sample holder further comprising a plurality of drawer sample slots receivable within a plurality of the sample chambers, respectively, the drawer sample slots being placed into or removed from the sample chambers through the outlets.
10. The biopsy device of claim 9, wherein the housing of the handle is provided with an annular outlet at a position corresponding to the outlet, and wherein an annular flap for opening and closing the outlet is provided at the outlet.
11. The multi-chamber sample holder biopsy device of claim 7, further comprising a vacuum aspiration tube comprising a main tube and a plurality of branch tubes, wherein one end of each of the plurality of branch tubes is in communication with a plurality of the sample chambers and the other end is in communication with the main tube.
12. A multi-chamber sample holder biopsy device according to claim 1, 2 or 3, wherein the input conduit drive comprises a stepper motor and a first gear train, an input of the first gear train being drivingly connected to an output shaft of the stepper motor, an output of the first gear train being drivingly connected to the input conduit.
13. The biopsy device of claim 12, wherein the stepper motor is disposed within the rear end of the handle with an output shaft of the stepper motor facing the front end of the handle and parallel to the rotational axis, wherein the first gear assembly comprises a third gear mounted on the output shaft of the stepper motor, a fourth gear coaxially mounted on the shaft with the fifth gear, the fourth gear engaged with the third gear, the sixth gear sleeved on the input conduit, and the sixth gear engaged with the fifth gear.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811287294.5A CN109199464B (en) | 2018-10-31 | 2018-10-31 | Biopsy device for multi-chamber sample holder |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811287294.5A CN109199464B (en) | 2018-10-31 | 2018-10-31 | Biopsy device for multi-chamber sample holder |
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| CN109199464A CN109199464A (en) | 2019-01-15 |
| CN109199464B true CN109199464B (en) | 2024-04-05 |
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| CN201811287294.5A Active CN109199464B (en) | 2018-10-31 | 2018-10-31 | Biopsy device for multi-chamber sample holder |
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| CN110037751B (en) * | 2019-04-25 | 2022-05-27 | 江苏华创高新医疗科技有限公司 | Sampling tool for tumor slices |
| CN114027888B (en) * | 2021-11-16 | 2022-11-15 | 重庆西山科技股份有限公司 | Windowing size adjusting method for sampling window of biopsy surgical device |
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|---|---|---|---|---|
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