CN105796135A - Vacuum-assisted mammary gland sample biopsy and rotary cutting system - Google Patents
Vacuum-assisted mammary gland sample biopsy and rotary cutting system Download PDFInfo
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- CN105796135A CN105796135A CN201610120357.2A CN201610120357A CN105796135A CN 105796135 A CN105796135 A CN 105796135A CN 201610120357 A CN201610120357 A CN 201610120357A CN 105796135 A CN105796135 A CN 105796135A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0041—Detection of breast cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
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Abstract
The invention relates to a vacuum-assisted mammary gland sample biopsy and rotary cutting system. A puncture head is fixedly connected to the front end of an outer cutter tube, a sampling groove is formed in the outer cutter tube, an inner cutter tube is sleeved with the outer cutter tube, a stirring disc is arranged at the rear end of the inner cutter tube which is connected with a transmission module, the transmission module is used for providing the two kinds of movements of rotating and advancing and retreating, a circuit control module is connected with the transmission module through a driving module to achieve driving control over the transmission module, and the vacuum-assisted mammary gland sample biopsy and rotary cutting system is controlled to perform cutting and suction surgical actions through operation buttons on the control module. By means of modularization and integration optimization design of a mechanical structure, the functions of surgical puncture, mechanical rotary cutting and vacuum suction are integrated in a probe region of the device, smaller surgical pain and postoperative trauma are caused on a patient with suspected mammary gland cancer with the smaller size of the system and the reasonable excision mode, and minimally-invasive biopsy sampling on a suspected tumor focus and minimally-invasive excision treatment on benign tumor can be achieved.
Description
Technical field
The present invention relates to a kind of breast biopsy system, particularly relate to vacuum aided mammary gland sample biopsy and biopsy system.
Background technology
In recent years, breast carcinoma has become one of fastest-rising tumor of sickness rate in China, and its sickness rate is increased beyond 3% every year, and age of onset also in rejuvenation trend, has a strong impact on the physical and mental health of women.In Shanghai, Beijing, the city such as Tianjin, breast carcinoma leaps to the first at female malignant.Wherein Shanghai female gynecological is sick, breast disease is occurred frequently, especially breast cancer incidence ranks first in the whole country, all Shanghai women de novo malignancy ranks first, account for 17%, just having 1 in every 6 female cancer patients is patient with breast cancer, more than annual new cases 5000 example, become the number one killer endangering women life and health in tumor.
Along with the quick growth of mastopathy sickness rate, biopsy syste is commonly used to help whether the cell that patient determines tested region is carcinous.A kind of vacuum aided breast biopsy and rotary cutting apparatus include disposable probe assembly and have the actuator assembly of vacuum source, mammary gland suspicious lesions can be repeated cutting, it is stored in sample collection device by vacuum draw, obtain the histological specimen of mammary gland, find for breast carcinoma and diagnosis provides more better method, also provide technical foundation for the excision of carcinoid Wicresoft simultaneously.
Breast biopsy on market today and biopsy system product mainly have the Encor of the Mammotome of Johnson Co., Bard company of the U.S..The Chinese patent CN200980158028.5 of above same kind of products at abroad application, CN201080054767.2, CN200710186190.0, CN200910126106.5, similar breast biopsy described in CN200910126107.X and CN200910126107.X and the equal non-integral single use of biopsy system product, structure is complicated, and Preoperative Method is loaded down with trivial details, handle portion needs disassembly, cleaning to sterilize after using, and deals with improperly and postoperative infection equivalent risk easily occurs；Different size of pathological tissues can only take specific several length sample, and sampling groove cannot realize stepless regulating, it is easy to switches to normal structure, and excessively excision increases the destruction to latex dust system；Double-tube structure, can obtain sampling amount under identical wound area few, and for the focus that volume is bigger, excision number of times increases.To some degree, doctor and patient are brought very big inconvenience, increase the medical expense of operation risk, treatment time and patient, it is impossible to perfection realizes the multi-functional of Wicresoft, biopsy and removal of lesions tissue.
Summary of the invention
The present invention is to solve that existing biopsy samples the process performed the operation complicated not good enough with safety, and the medical apparatus system of the high integration optimizing patient's operation method and corrective surgery experience and designing.
nullFor reaching above-mentioned purpose，The technical solution used in the present invention is: a kind of vacuum aided mammary gland sample biopsy and biopsy system，By vacuum aided mammary gland sample biopsy and biopsy system head application end、Circuit control module、Drive module、Transmission module、Applicator forms，It is characterized in that: described vacuum aided mammary gland sample biopsy and biopsy system head application end include puncturing head、Interior cutter pipe、Sampling groove、Outer cutter pipe、Driver plate，Described puncturing head is fixedly connected on outer cutter pipe front end，Outer cutter pipe has sampling groove，Interior cutter pipe box is in outer cutter pipe，Interior cutter pipe rear end is provided with driver plate，Sampling groove 360 ° rotation can be realized by driver plate，Interior cutter pipe is connected with transmission module，The two kinds of motions that rotate and retreat are provided by transmission module，Described circuit control module connects transmission module by driving module，Realize the driving of transmission module is controlled，And by controlling the operation button in module，Control vacuum aided mammary gland sample biopsy to cut with biopsy system、Aspiration operation action，And cutter pipe backway in regulating according to size of tumor，Realize the stepless regulating of sampling groove length；Described applicator is connected with transmission module by unscrewing type joint, and is connected on the general negative pressure source of hospital or dedicated servo negative pressure equipment by extending pipeline and pipe joint, negative pressure source continue to aspirate.
Described puncturing head, outer cutter pipe and interior cutter tube material all adopt the high-hardness stainless steel meeting biocompatibility requirement.Described transmission module, driving module, control module are arranged in the same handle shell, form modular construction.
Described applicator is single chamber or three chambeies or six chambeies or 12 chamber applicator, described applicator collectively forms vacuum chamber when vacuum aided mammary gland sample biopsy performs sampling operation with biopsy system head application end with interior cutter pipe, draw tissue into sampling groove, interior cutter pipe after cutting again suction and conveying to applicator；At intra-operative, tissue samples that applicator cuts for storing and rinse protection or extract sample at any time out and carry out on-the-spot biopsy；Doctor, after surgery if it is desired, applicator pulled down, utilizes the interior cutter tube passage that syringe or conduit are formed after puncturing entrance by application end that focal area is discharged target therapeutic agent.
Described applicator is single chamber applicator, including single chamber catcher bottle, sample grid, single chamber catcher end cap, axial sealing ring, sample grid and single chamber catcher end cap are by snapping connection, axial sealing ring is buckled in catcher end cap seal groove, and forms sealing with single chamber catcher bottle inwall interference fit.
Described applicator is three chamber applicator, including combined type catcher bottle, sample grid bunch, applicator end cap, grid pillar, hold to sealing ring, grid sealing ring, sample grid bunch snaps in grid pillar by draw-in groove, applicator end cap interlocks with the sealing of combined type catcher bottle to sealing ring by holding, grid pillar passes through grid sealing ring and three chamber catcher end cap circumference interference fit, is formed and seals.
The invention has the beneficial effects as follows:
1. the biopsy of vacuum aided mammary gland sample and biopsy system overall time operational version can be greatly improved operation safety, reduce infection rate, improve procedure efficiency simultaneously and experience with surgical；Use rear apparatus entirety to abandon, omit the links such as cleaning and sterilizing apparatus.
2. the biopsy of vacuum aided mammary gland sample and biopsy system application end adopt coaxial interior cutter water jacket mode to realize; probe structure is compact; compare like product and can obtain bigger focus sample under identical wound area; sampling groove also can be regulated according to focal size flexible in size by doctor simultaneously; reduce or avoid switching to normal structure, protect normal galactophore tissue；
3. applicator adopts fast assembling disassembling structure, and in operation, doctor can quickly extract sample grid and obtain real-time sample, it is possible to pulls down and replaces applicator.The present invention has multiple multi-form applicator, and wherein single chamber catcher is applicable to single large volume focus, extracts sample grid and can obtain real-time sample and carry out biopsy；Multi-cavity catcher is applicable to multiple focus situations, diverse location focus sample can be carried out categorised collection, it is possible to storage excision thing.
The present invention is from user angle, and by modularity, Integration Design, it is thus achieved that compact conformation, excision efficiently, uses degree of freedom big, multiple functional reliable breast biopsy and biopsy system.Simplify and while flexibility surgical operation, alleviate pain and post-operative complication in patient's art, optimizing surgical quality.
Accompanying drawing explanation
Fig. 1 is the vacuum aided mammary gland sample biopsy structural upright schematic diagram with biopsy system of the present invention；
Fig. 2 is the partial enlarged drawing at A place in Fig. 1；
Fig. 3 is single chamber applicator structural upright exploded view；
Fig. 4 is three chamber applicator structural upright exploded views.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the present invention is expanded on further.
Such as Fig. 1, shown in 2, a kind of vacuum aided mammary gland sample biopsy and biopsy system, be made up of with biopsy system head application end, circuit control module 7, driving module 8, transmission module 6, applicator 9, prolongation pipeline 10, pipe joint 11 etc. vacuum aided mammary gland sample biopsy.
Vacuum aided mammary gland sample biopsy and biopsy system head application end include puncturing head 1, interior cutter pipe 2, sampling groove 3, outer cutter pipe 4, driver plate 5.Puncturing head 1 is fixedly connected on outer cutter pipe 4 front end, outer cutter pipe 4 has sampling groove 3, interior cutter pipe 2 is placed in outer cutter pipe 4, interior cutter pipe 4 rear end is provided with driver plate 5, 360 ° of rotations of sampling groove 3 can be realized by driver plate 5, interior cutter pipe 4 is connected with transmission module 6, interior cutter pipe 4 is provided rotation and two kinds of motions of retreating by transmission module 6, the precessional motion of interior cutter pipe 2 front end cutting edge can form " shears effect " with sampling groove 3 thus cutting the focus sample sucking sampling groove 3, vacuum aided mammary gland sample biopsy and biopsy system head application end, guided by puncturing head 1, penetrate under contrast apparatus in patient body, and reach lesions position, in operation, doctor can realize the rotation to sampling groove 3 by stirring driver plate 5, thus the tissue samples that can obtain in different azimuth.Circuit control module 7 realizes the driving to transmission module 6 by controlling driving module 8, thereby through the operation button controlled in module 7, doctor can control vacuum aided mammary gland sample biopsy and biopsy system carry out cutting, the surgical action such as suction, and according to cutter pipe 2 backway in size of tumor flexible, realize the stepless regulating of sampling groove 3 length, to reach to reduce the purpose of normal tissue injury.Applicator 9 is connected with transmission module 6 by unscrewing type joint, doctor is facilitated to dismount as required in operation, applicator 9 is tightly connected with extending pipeline 10, and it is connected on the general negative pressure source of hospital or dedicated servo negative pressure equipment by pipe joint 11, continued to aspirate by negative pressure source, high vacuum is formed in applicator 9 with interior cutter pipe 2, thereby through the straight trough on interior cutter pipe 2 front end, lesion tissue is sucked in sampling groove 3, also delivered to by vacuum draw after focus sample is cut in the sample grid 13 of applicator 9.Can leading to normal saline in pipe joint 11, in operation process, normal saline enters in applicator 9 can the flushing protection of complete paired samples.Puncturing head 1, outer cutter pipe 4 and interior cutter pipe 2 material all adopt the high-hardness stainless steel meeting biocompatibility requirement, and its cutting edge and rib mouth are through high-precision grinding, it is possible to readily pass through and cut hardening lesion tissue；Interior cutter pipe 2, by rotating and advancing, coordinates sampling groove 3 mouthfuls, can the lesion tissue that suck in sampling groove 3 be cut；Circuit control module 7 can pass through the distance changing interior cutter pipe 2 retrogressing thus realizing the electrodeless adjustment of sampling groove 3 length, it is to avoid crosses and cuts normal structure；The shape design of puncturing head 1 can strengthen contrasting effects；Driver plate 5 and outer cutter pipe) it is connected, it may be achieved 360 ° of rotations of sampling groove 3, facilitate doctor to obtain the tissue samples in different azimuth.
Applicator 9 has four kinds of different sizes, and doctor can select single chamber or three chambeies or six chambeies or 12 chambeies, different size applicator according to the size of tumor that radiography shows and quantity) between can quickly realize disassembling, assembling and replacing；Applicator 9 application end perform sampling operation time with interior cutter pipe 2 collectively form vacuum chamber, draw tissue into sampling groove), interior cutter pipe 2 after cutting again suction and conveying to applicator 9；In intra-operative applicator 9 for storing and rinse the tissue samples that protection is cut, it is possible to extract sample at any time out and carry out on-the-spot biopsy.Interior cutter pipe 2 passage is the physical channel formed after application end punctures entrance, and doctor if it is desired, can applicator 9 be pulled down, utilizes syringe or conduit that focal area is discharged target therapeutic agent after surgery.
As shown in Figure 3, the applicator 9 of single chamber pattern of the present invention, single chamber catcher bottle 12 is connected with transmission module 6 by unscrewing type joint, sample grid 13 and single chamber catcher end cap 14 are by snapping connection, axial sealing ring 15 is buckled in catcher end cap seal groove, and forms sealing with single chamber catcher bottle 12 inwall interference fit.
As shown in Figure 4, the applicator 9 of the three chamber patterns of the present invention, combined type catcher bottle 16 is connected with transmission module 6 by unscrewing type joint, sample grid bunch 17 snaps in grid pillar 19 by draw-in groove, applicator end cap 18 interlocks with the sealing of combined type catcher bottle 16 to sealing ring 20 by holding, grid pillar 19, by grid sealing ring 21 and three chamber catcher end cap 18 circumference interference fit, is consequently formed sealing.
Application Example one:
Showing single mammary gland tumor under radiography, its long end diameter is about 25mm, now should select single chamber applicator, and sampling groove 3 length is set as total length pattern.
List chamber applicator 9 is inserted transmission module 6 rear end, and turn clockwise locking after 90 °, then the vacuum pipe extended in pipeline 10 and flushing pipe are respectively connected to applicator 9 back end interface.After Preoperative Method completes, according to routine operation flow process, guide to puncture application end according to radiography and enter lump focal area, arrival target bearing, sampling groove 3 direction is adjusted by driver plate 5, set sampling groove 3 by control module 7 and open length, because tumor is relatively big, adopt total length pattern to be sampled operation, sampled in the sample grid 13 that rear sample can be automatically sent in applicator 9.If art needs sample is carried out on-the-spot biopsy, then extract after half-twist list chamber catcher end cap 14 counterclockwise, after taking out sample, catcher end cap 14 is turned back in single chamber catcher bottle 12 together with sample grid 13, and turn clockwise 90 ° and lock.As need to be above-mentioned size lump excised completely, then repeated sampling is needed to operate, until showing excision profile clearly under radiography.
Application Example two:
Showing multiple mammary gland tumor bunch under radiography, its average long end diameter is about 5mm, now should select three-chamber applicator, and sampling groove 3 length can be set to about 1/2nd of total length.
Three-chamber applicator 9 is inserted transmission module 6 rear end, and turn clockwise locking after 90 °, then the vacuum pipe extended in pipeline 10 and flushing pipe are respectively connected to applicator end cap (18) back end interface.After Preoperative Method completes, according to routine operation flow process, guide to puncture application end according to radiography and enter lump focal area, arrival target bearing, sampling groove 3 direction is adjusted by driver plate 5, set sampling groove 3 by circuit control module 7 and open length, because tumor is less, can be selected for 1/2nd of sampling groove 3 total length and be sampled operation, sampled in one of them chamber of the sample grid bunch 17 that rear sample can be automatically sent in applicator 9.If art needing sample carries out on-the-spot biopsy, then grid pillar 19 is extracted from afterwards, open the sample grid bunch 17 at sample place, after taking out sample, grid pillar 19 even sample grid bunch 17 is together turned back in three-chamber catcher bottle 16.As diverse location lump sample carried out classified storage, grid pillar 19 is rotated clockwise or counterclockwise, make the sample cut out be admitted in different sample grid bunch 17 chambers.
Application Example three:
Need after having performed the operation focal area is discharged target therapeutic agent.
Extract after backward for half-twist counterclockwise for applicator 9, expose interior cutter pipe 2 rear end, in the syringe of conveying medicine or conduit are inserted in cutter pipe 2, targeted release medicine, vacuum aided mammary gland sample biopsy being extracted from patient's mammary gland with biopsy system entirety after completing operation, entirety does waste treatment.
Vacuum aided mammary gland sample biopsy of the present invention and biopsy system generally single use, and the general vacuum suction source of hospital or dedicated servo vacuum source can be connected, increase its universality.
Vacuum aided mammary gland sample biopsy of the present invention and biopsy system application end compact conformation, sampling groove adjustable length, compares like product and can obtain bigger focus sample under identical wound area, improve procedure efficiency, facilitate doctor to operate, and reduce patient pain.
Applicator of the present invention has four kinds of structures, is supplied to the multiple sample collection means of doctor, can tackle flexibly as required.
Claims (6)
- null1. a vacuum aided mammary gland sample biopsy and biopsy system，By vacuum aided mammary gland sample biopsy and biopsy system head application end、Circuit control module (7)、Drive module (8)、Transmission module (6)、Applicator (9) forms，It is characterized in that: described vacuum aided mammary gland sample biopsy and biopsy system head application end include puncturing head (1)、Interior cutter pipe (2)、Sampling groove (3)、Outer cutter pipe (4)、Driver plate (5)，Described puncturing head (1) is fixedly connected on outer cutter pipe (4) front end，Outer cutter pipe (4) has sampling groove (3)，Interior cutter pipe (2) is placed in outer cutter pipe (4)，Interior cutter pipe (4) rear end is provided with driver plate (5)，Sampling groove (3) 360 ° rotation can be realized by driver plate (5)，Interior cutter pipe (4) is connected with transmission module (6)，The two kinds of motions that rotate and retreat are provided by transmission module (6)，Described circuit control module (7) connects transmission module (6) by driving module (8)，Realize the driving of transmission module (6) is controlled，And control vacuum aided mammary gland sample biopsy and biopsy system by the operation button on circuit control module (7) and cut、Aspiration operation action，And cutter pipe (2) backway in regulating according to size of tumor，Realize the stepless regulating of sampling groove (3) length；Described applicator (9) is connected with transmission module (6) by unscrewing type joint, and is connected on the general negative pressure source of hospital or dedicated servo negative pressure equipment by extending pipeline (10) and pipe joint (11), negative pressure source continue to aspirate.
- 2. vacuum aided mammary gland sample biopsy according to claim 1 and biopsy system, it is characterised in that: described puncturing head (1), outer cutter pipe (4) and interior cutter pipe (2) material all adopt the high-hardness stainless steel meeting biocompatibility requirement.
- 3. vacuum aided mammary gland sample biopsy according to claim 1 and biopsy system, it is characterised in that: described transmission module (6), driving module (8), control module (7) are arranged in the same handle shell, form modular construction.
- 4. vacuum aided mammary gland sample biopsy according to claim 1 and biopsy system, it is characterized in that: described applicator (9) is single chamber or three chambeies or six chambeies or 12 chamber applicator, described applicator (9) collectively forms vacuum chamber when vacuum aided mammary gland sample biopsy performs sampling operation with biopsy system head application end with interior cutter pipe (2), draw tissue into sampling groove (3), interior cutter pipe (2) after cutting again suction and conveying to applicator (9)；At intra-operative, tissue samples that applicator (9) cuts for storing and rinse protection or extract sample at any time out and carry out on-the-spot biopsy；Doctor, after surgery if it is desired, applicator (9) pulled down, utilizes interior cutter pipe (2) passage that syringe or conduit are formed after puncturing entrance by application end that focal area is discharged target therapeutic agent.
- 5. vacuum aided mammary gland sample biopsy according to claim 4 and biopsy system, it is characterized in that: described applicator (9) is single chamber applicator, including single chamber catcher bottle (12), sample grid (13), single chamber catcher end cap (14), axial sealing ring (15), sample grid (13) and single chamber catcher end cap (14) are by snapping connection, axial sealing ring (15) is buckled in catcher end cap seal groove, and forms sealing with single chamber catcher bottle (12) inwall interference fit.
- 6. vacuum aided mammary gland sample biopsy according to claim 4 and biopsy system, it is characterized in that: described applicator (9) is three chamber applicator, including combined type catcher bottle (16), sample grid bunch (17), applicator end cap (18), grid pillar (19), hold to sealing ring (20), grid sealing ring (21), sample grid bunch (17) snaps in grid pillar (19) by draw-in groove, applicator end cap (18) interlocks with combined type catcher bottle (16) sealing to sealing ring (20) by holding, grid pillar (19) is by grid sealing ring (21) and three chamber catcher end cap (18) circumference interference fit, formed and seal.
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| CN201610120357.2A CN105796135A (en) | 2016-03-03 | 2016-03-03 | Vacuum-assisted mammary gland sample biopsy and rotary cutting system |
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| CN201610120357.2A CN105796135A (en) | 2016-03-03 | 2016-03-03 | Vacuum-assisted mammary gland sample biopsy and rotary cutting system |
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| CN106236153A (en) * | 2016-09-30 | 2016-12-21 | 杭州思客医学科技有限公司 | The needle head structure of a kind of rotary-cut pin and rotary-cut pin thereof |
| CN106388871A (en) * | 2016-08-31 | 2017-02-15 | 重庆西山科技股份有限公司 | Rotary varicotomy tool synchronous monitoring method and system |
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