CN109192844A - One kind is repaired and regenerated LED light emitting device and application for retina cell - Google Patents
One kind is repaired and regenerated LED light emitting device and application for retina cell Download PDFInfo
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- CN109192844A CN109192844A CN201811004355.2A CN201811004355A CN109192844A CN 109192844 A CN109192844 A CN 109192844A CN 201811004355 A CN201811004355 A CN 201811004355A CN 109192844 A CN109192844 A CN 109192844A
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- 238000002360 preparation method Methods 0.000 claims description 4
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
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- QDOXWKRWXJOMAK-UHFFFAOYSA-N chromium(III) oxide Inorganic materials O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 description 2
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- 102000004190 Enzymes Human genes 0.000 description 1
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Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L33/00—Semiconductor devices having potential barriers specially adapted for light emission; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof
- H01L33/48—Semiconductor devices having potential barriers specially adapted for light emission; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof; Details thereof characterised by the semiconductor body packages
- H01L33/50—Wavelength conversion elements
- H01L33/501—Wavelength conversion elements characterised by the materials, e.g. binder
- H01L33/502—Wavelength conversion materials
- H01L33/504—Elements with two or more wavelength conversion materials
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L2933/00—Details relating to devices covered by the group H01L33/00 but not provided for in its subgroups
- H01L2933/0008—Processes
- H01L2933/0033—Processes relating to semiconductor body packages
- H01L2933/0041—Processes relating to semiconductor body packages relating to wavelength conversion elements
Landscapes
- Engineering & Computer Science (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Manufacturing & Machinery (AREA)
- Computer Hardware Design (AREA)
- Power Engineering (AREA)
- Luminescent Compositions (AREA)
- Led Device Packages (AREA)
Abstract
It repairs the invention discloses a kind of retina cell and is set on the pedestal with regenerated LED light emitting device, including pedestal and excitation light source, the excitation light source, the excitation light source includes LED chip and phosphor powder layer, and the LED chip is fixedly arranged on pedestal;The phosphor powder layer includes layer of silica gel, is dispersed with fluorescent powder in the layer of silica gel, which is fixedly arranged on LED chip on the end face of pedestal;The launch wavelength of the LED chip is 200-520nm, and under the excitation of LED chip, the launch wavelength of the fluorescent powder is 570-850nm.The invention also discloses the applications of the LED light emitting device.It is an advantage of the current invention that it can generate the far red light for being beneficial to vision health, promote the reparation and regeneration of retina cell, reduces blue light harm.
Description
Technical field
The invention belongs to semiconductor lighting, biologic medical and vision health technical fields, and in particular to one kind is used for view
Theca cell reparation and regenerated LED light emitting device and application.
Background technique
For human eyesight health, far-red light is extremely important near infrared light.Far-red light can promote near infrared light
Into the reparation and regeneration of retina cell, essence be far-red light and near infrared light stimulation can be improved mitochondria function it is living
Property, and then improve the reparation and power of regeneration of cell.
Mitochondria is the place that cellular respiration generates energy, and atriphos (ATP) is the fuel of cellular energy, is raw
The most direct energy source of object.Life can survive a few minutes in the environment of no oxygen supply, but if all ATP are supplied
It should stop suddenly, people will be dead in 15 seconds.There are light absorbing chromophores in cytochrome C oxidase in mitochondria
(chromophore) molecule, i.e. mitochondrial respiratory chain complex IV (complex IV).So cytochrome c oxidase is red
The receiver and signal transducer of light and near infrared light.Cytochrome c oxidase is the terminal enzyme of electron-transport chain, in mitochondria
Light is absorbed before the middle final step for generating ATP.By a series of redox reactions, electron-transport chain facilitate electronics across
The inner membrance of mitochondria is transmitted.Specifically, facilitating in cytochrome c oxidase catalysis after organism contact far-red light
The available electron number that the heart restores oxygen molecule increases, and increases the potential of mitochondrial membrane, improves ATP, cyclic adenosine monophosphate (cAMP)
With the concentration level of reactive oxygen species (reactive oxygen species, ROS), and then improve cell metabolism, promotion group
Blood flow, excitation nerve and the neurite outgrowth knitted.And in organism, be conducive to the critical wavelength range that cell generates energy
It is 570-850nm.
LED is used widely because of its significant advantage with energy-saving and environmental protection.But at present in illuminator and display
The LED applied in backlight mainly utilizes InGaN blue chip excitated fluorescent powder to encapsulate, general to reach energy-saving effect
It is yellow, red, green or hanced cyan fluorescent powder all over the fluorescent powder used, it is visible that the launch wavelength of LED is limited in 400-700nm
In optical range, lack far-red light within the scope of the 700-850nm beneficial to human body vision health.With LED lamp lighting with
The application of display backlight source it is universal, especially recent years smart phone is universal, LED light source to the injury of human body eyesight more
Seriously.
Summary of the invention
Technical problem to be solved by the present invention lies in: existing LED light source is extremely serious to the injury of eyesight.
The present invention solves above-mentioned technical problem using following technical scheme:
A kind of retina cell's reparation and regenerated LED light emitting device, including pedestal and excitation light source, the excitation light source
It is set on the pedestal, the excitation light source includes LED chip and phosphor powder layer, and the LED chip is fixedly arranged on pedestal;Institute
Stating phosphor powder layer includes layer of silica gel, is dispersed with fluorescent powder in the layer of silica gel, which is fixedly arranged on LED chip away from pedestal
End face on;The launch wavelength of the LED chip is 200-520nm, under the excitation of LED chip, the transmitting of the fluorescent powder
Wavelength is 570-850nm.
Preferably, a kind of retina cell of the present invention repair with regenerated LED light emitting device, the fluorescent powder by
Red light fluorescent powder is mixed with far-red light fluorescent powder, and under the excitation of LED chip, the red light fluorescent powder launch wavelength exists
The feux rouges of 570-700nm, the feux rouges carry out secondary excitation to far-red light fluorescent powder, and the launch wavelength of far-red light fluorescent powder is 700-
850nm。
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the feux rouges fluorescence
The centre of luminescence of powder is Eu2+, luminous host is nitride.
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the luminous host
For A0.5+0.5yAlySi2-yN3Or B2-δD5N8Oδ, wherein A is Ca or Sr and 1.0 < y < 2.0, B Sr, Ba or Ca, D for Al or Si and
0≤δ < 1.0.
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the feux rouges fluorescence
Powder is (Ca1-zEuz)0.5+0.5yAlySi2-yN3, wherein 1.0 < y < 2.0,0 < z < 0.05.
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the far-red light are glimmering
The centre of luminescence of light powder is Cr3+, luminous host is the high symmetry oxide of fluoride, oxygen fluoride or garnet structure.
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the luminous host
It is L when for fluoride3ExF6Or LLnF4, wherein L is K or Na, any one of E Al, Ga, Sc, Y, La, Gd or Lu, Ln
For any one of Sc, Y, La, Gd or Lu, and the sum of the atom number of E and the atom number of Cr are 1;
It is M when the luminous host is oxygen fluoride3RO4FO, wherein M is Sr or Ca, and R is Al or Si;
When the luminous host is garnet high symmetry oxide, it is selected from T3X5O12、Z3Al2(SiO4)3Or
Y2CaMg2(SiO4)3, wherein T is any one of Y, Ga, Lu or Tb, and X Al, Ga or Sc, Z is Ca or Mg.
Preferably, a kind of retina cell of the present invention repairs and regenerated LED light emitting device, the far-red light are glimmering
Light powder is [L3(ExCr1-x)]F6, wherein 0 < x < 1.0, preparation method is as follows:
(1) CrF is weighed according to the value of x3, LF and L3EF3, wherein LF and L3EF6Molar ratio be 0:1-3:1;
(2) by CrF3It pours into polyvinyl fluoride reactor, hydrofluoric acid is added, stirs to dissolve;
(3) LF is added into the product of step (2), L is added after LF dissolution3EF6, reactor is sealed, is stirred to react;
(4) after reaction to step (3), stop stirring, reaction product is filtered, it is anti-using acetone repeated flushing
Product is answered, until inspection does not measure acidity;
(5) it takes reaction product to dry under 70 DEG C of vacuum conditions, obtains the far-red light fluorescent powder.
The present invention also provides a kind of above-mentioned applications repaired for retina cell with regenerated LED light emitting device.
Preferably, a kind of application repaired for retina cell with regenerated LED light emitting device of the present invention,
Application in display backlight source or lighting source.
The technology of the present invention the utility model has the advantages that
Technical solution of the present invention is by improving LED excitation light source, so that the light inspired has the view to damage
Regenerated non-vision function is repaired and promoted to retinulae, especially by this itself and the rich blue cool white light LED device of conventional binary
Part is used cooperatively, and can be effectively reduced blue light harm, improves vision health;
The LED light emitting device is used in combination with lighting source or display backlight source, can in the daytime, night etc.
It is independently controlled under different light conditions, plays good energy-saving effect.
Detailed description of the invention
Fig. 1 is that one kind described in one kind of the embodiment of the present invention is repaired and regenerated LED light emitting device for retina cell
Structural schematic diagram;
Fig. 2 is the spectrogram of the far-red light of the transmitting of LED light emitting device described in embodiment one;
Fig. 3 is the spectrogram of the far-red light of the transmitting of LED light emitting device described in embodiment two;
Fig. 4 is the spectrogram of the far-red light of the transmitting of LED light emitting device described in embodiment three;
Fig. 5 is that the LED light emitting device for preparing embodiment one in example IV is applied to the structural schematic diagram of desk lamp;
Fig. 6 is that the LED light emitting device that embodiment five prepares embodiment two or embodiment three is applied to display backlight source
In structural schematic diagram;
Fig. 7 is the retinal structure figure of various mouse in embodiment six, and wherein A is A group Mouse Retina structure chart;B is B
Group Mouse Retina structure chart;C is C group Mouse Retina structure chart;D is D group Mouse Retina structure chart.
Specific embodiment
For convenient for those skilled in the art understand that technical solution of the present invention, now in conjunction with Figure of description to the technology of the present invention side
Case is described further.
Fig. 1 show a kind of retina cell provided by the invention and repairs and regenerated LED light emitting device 1 comprising base
Seat 11 and excitation light source 12, the excitation light source 2 are set to one complete LED light emitting device of composition on the pedestal 1.
The excitation light source 12 includes LED chip 121 and phosphor powder layer 122, and the LED chip 121 is fixedly arranged on holding tank
It is interior;The phosphor powder layer 122 includes layer of silica gel 1221, is dispersed with fluorescent powder 1222 in the layer of silica gel 1221, the phosphor powder layer
LED chip is fixedly arranged on the end face of pedestal 11.
The LED chip can be launch wavelength in the blue chip of 400-520nm, be also possible to launch wavelength in 300-
The near ultraviolet chip of 400nm can also be launch wavelength in the ultraviolet chip of 200-300.
The fluorescent powder is described under the excitation of LED chip by being mixed by red light fluorescent powder and far-red light fluorescent powder
Red light fluorescent powder launch wavelength is in the feux rouges of 570-700nm, and for the feux rouges to far-red light fluorescent powder progress secondary excitation, far-red light is glimmering
The launch wavelength of light powder is 700-850nm.
More specifically, the centre of luminescence of the red light fluorescent powder is Eu2+, luminous host is nitride A0.5+0.5yAlySi2-yN3Or B2-δD5N8Oδ, wherein A is Ca or Sr and 1.0 < y < 2.0, B Sr, Ba or Ca, and D is Al or Si and 0≤δ <
1.0。
The centre of luminescence of the far-red light fluorescent powder is Cr3+, there are many selections for luminous host, such as when luminous host is
It is L when fluoride3ExF6Or RLnF4, wherein L is K or Na, any one of E Al, Ga, Sc, Y, La, Gd or Lu, and Ln is
Any one of Sc, Y, La, Gd or Lu, the sum of the atom number of E and the atom number of Cr are 1 at this time;When luminous host is oxygen
It is M when fluoride3RO4FO, wherein M is Sr or Ca, and R is Al or Si;When luminous host is garnet high symmetry oxidation
When object, it is selected from T3X5O12、Z3Al2(SiO4)3Or Y2CaMg2(SiO4)3, wherein T is any one of Y, Ga, Lu or Tb, and X is
Al, Ga or Sc, Z are Ca or Mg.
With Cr3+D-d track is derived from for its luminescence mechanism of the far-red light fluorescent powder of the centre of luminescence.Due to-d the track of d electronics
Transition is parity forbidden, lattice coordination environment and symmetry are relied on it is unobvious, but by Cr3+It is placed in different crystal field intensity
Coordination environment in, based on crystalline field splitting energy level difference, emission wavelength can be regulated and controled, obtain the hair of different wave length
Penetrate light.Identical effect can be generated by being thus replaced in luminous host using not homoatomic.
At large illustrated below by specific embodiment come the LED light emitting device obtained to the present invention.
Embodiment one
It is as shown in Figure 1 the concrete structure schematic diagram of LED component described in the present embodiment, in the present embodiment, the base
Seat 11 and LED chip 121 purchase Guangdong Jing Ke Electronics Co., Ltd..
Refering to fig. 1, the holding tank of a recess is formed on the pedestal 11, pedestal 11 is set on end face where holding tank
There is electrode 13, the LED chip 121 is installed in the bottom of holding tank, and LED chip 121 is electrical by conducting wire and the electrode 13
Connection.After red light fluorescent powder is mixed with far-red light fluorescent powder with AB transparent silica gel, through vacuum defoamation, reuse dispenser by its
LED chip 121 is dripped to towards on the one side outside pedestal 11, under vacuum conditions, is configured to through 150 DEG C of baking-curings
The LED light emitting device that can independently shine under DC powered.
Red light fluorescent powder (Ca1-zEuz)0.5+0.5yAlySi2-yN3, 1.0 < y < 2.0,0 < z < 0.05, the selection of far-red light fluorescent powder
[L3(ExCr1-x)]F6, the mixed effect in 0 < x < 1.0 is preferable.
Specifically, red light fluorescent powder used is (Ca in this implementation0.996Eu0.004)1.1Al1.2Si0.8N3, far-red light fluorescent powder
For K3Al0.94Cr0.06F6。
(Ca0.996Eu0.004)1.1Al1.2Si0.8N3Red light fluorescent powder uses solid reaction process to synthesize: with Ca3N2、AlN、Si3N4
And Eu3N2For raw material, raw material is fully ground under nitrogen atmosphere protection first, the product after grinding is then packed into graphite earthenware
Crucible is put into pressure furnace, in N2In 1600-1900 DEG C into high-temperature calcination 3-10 hours under atmosphere protection, sample come out of the stove after through crushing
It handles to get red light fluorescent powder finished product is arrived.
K3Al0.94Cr0.06F6Far-red light fluorescent powder is prepared by following methods: (1) weighing CrF3, LF and L3EF3, wherein LF
With L3EF6Molar ratio be 0:1-3:1;(2) by CrF3It pours into polyvinyl fluoride reactor, hydrofluoric acid is added, stirring keeps its molten
Solution;(3) LF is added into the product of step (2), L is added after LF dissolution3EF6, reactor is sealed, is stirred to react;(4) to
Step (3) after reaction, stops stirring, filters to reaction product, using acetone repeated flushing reaction product, until inspection
Acidity is not measured;(5) it takes reaction product to dry under 70 DEG C of vacuum conditions, obtains the far-red light fluorescent powder.
The LED light emitting device being prepared to the present embodiment is passed through direct current, and uses marine optics USB4000 optical fiber light
Spectrometer acquires its luminescent spectrum, and as a result as shown in Fig. 2, can be seen in the figure from spectrum, the wavelength of LED light emitting device transmitting exists
Within the scope of 570-850nm.
Embodiment two
The difference between this embodiment and the first embodiment lies in the far-red light fluorescent powder uses Y3Al5O12As luminous
Matrix, the far-red light fluorescent powder are prepared by following methods: with Y2O3、Al2O3And Cr2O3For raw material, it is added helps thereto
Solvent is packed into corundum crucible after ball mill mixing, then the high-temperature calcination in Muffle furnace through 1250-1650 DEG C, after the reaction was completed
It is broken.
Above-mentioned Cr2O3As Cr3+Cr (NO can also be used3)3Instead of BaF can be used in the cosolvent2、AlF3
Or H3BO3, according to raw material dosage, calcination time 2-10h.
It is powered to LED light emitting device manufactured in the present embodiment, collects spectrum as shown in Figure 3, it is known that its wavelength exists
570-850nm。
It should be noted that the far-red light fluorescent powder in the present embodiment can also use other height with garnet structure
Symmetry oxide replaces, and in the preparation, uses rare earth oxide Ln according to specific structure2O3、Tb4O7、Al2O3、SiO2, alkali
Metal oxide MO is as reaction raw materials.
Embodiment three
The present embodiment and the difference of embodiment three are that the red light fluorescent powder in the present embodiment uses Ba1.5Al5N8O0.5, institute
Far-red light fluorescent powder is stated using Sr3SiO4FO.The Ba1.5Al5N8O0.5And Sr3SiO4The preparation method of FO is conventional method,
Details are not described herein again.
It is powered to LED light emitting device manufactured in the present embodiment, collects spectrum as shown in Figure 4, it is known that its wavelength exists
570-850nm。
Example IV
Refering to Fig. 5, LED light emitting device 1 made from embodiment one and common desk lamp are bonded a healthy desk lamp.General
At least one embodiment one is set between the white light lamp bead 2 of logical desk lamp, LED light emitting device 1 is made, wherein the LED light emitting device 1
Power on/off is controlled by different power switches from white light lamp bead 2.
When using the health desk lamp in the daytime, because there is far-red light spectral component abundant in sunlight, therefore only need to open
White light lamp bead 2 is to reach energy-efficient purpose.Under night or the insufficient situation of sunlight, white light lamp bead and LED hair can be opened simultaneously
Optical device supplements far-red light, reaches the reparation and palingenesis to retina cell.
Embodiment five
Refering to Fig. 6, combines LED light emitting device prepared by embodiment two or embodiment three with other white light LEDs lamp beads 3 and answer
For display backlight source, which is positioned apart between white light LEDs lamp bead 3.Similarly, two kinds of LED components
Separate configurations switch.
Embodiment six
Illumination experiment is carried out to mouse using different light sources.Taking 20 weight is the SD hero mouse of 200-220g, stochastic averagina
It is divided into tetra- groups of A, B, C, D, wherein A group uses blue light illumination, and B group is irradiated simultaneously using blue light and far red light, and C group uses feux rouges
Irradiation, D group are irradiated simultaneously using feux rouges and far-red light.In the case where other conditions are identical, to four groups of every daylight of mouse
According to 4 hours, remaining time kept normal light and shade variation, was carried out continuously one week.Eyeball of mouse view is taken within two days after stopping illumination
Film carries out HE dyeing, observes the variation of each group Mouse Retina structure.Table 1 is light source parameters used.
1 mouse experiment of table is various to use light source parameters
Experimental result is referring to Fig. 7, and wherein A is the retinal structure of A group mouse, and B is the retinal structure of B group mouse, and C is
The retinal structure of C group mouse, D are the retinal structure of D group mouse.By comparing, INL, ONL confluent monolayer cells density of A group are bright
Aobvious to be lower than B group, INL, ONL confluent monolayer cells density of C group are significantly lower than D group, and thus provable far red light is for retinal damage
Protection and therapeutic effect are truly had, i.e., far red light, which has, promotes retina cell to repair and regenerated effect.
Above-mentioned INL layer refers to that the inner nuclear layer of retina, ONL refer to the outer nuclear layer of retina.
Technical solution of the present invention is exemplarily described invention above in conjunction with attached drawing, it is clear that present invention specific implementation
It is not subject to the restrictions described above, changes as long as using the various unsubstantialities that the inventive concept and technical scheme of the present invention carry out
Into, or it is not improved the conception and technical scheme of invention are directly applied into other occasions, in protection scope of the present invention
Within.
Claims (10)
- It is set 1. a kind of retina cell repairs with regenerated LED light emitting device, including pedestal and excitation light source, the excitation light source It is placed on the pedestal, which is characterized in that the excitation light source includes LED chip and phosphor powder layer, and the LED chip is fixedly arranged on On pedestal;The phosphor powder layer includes layer of silica gel, is dispersed with fluorescent powder in the layer of silica gel, which is fixedly arranged on LED core Piece is on the end face of pedestal;The launch wavelength of the LED chip is 200-520nm, described glimmering under the excitation of LED chip The launch wavelength of light powder is 570-850nm.
- 2. a kind of retina cell according to claim 1 repairs and regenerated LED light emitting device, which is characterized in that institute Fluorescent powder is stated to be mixed by red light fluorescent powder and far-red light fluorescent powder, under the excitation of LED chip, the red light fluorescent powder hair Ejected wave grows the feux rouges in 570-700nm, which carries out secondary excitation, the transmitted wave of far-red light fluorescent powder to far-red light fluorescent powder A length of 700-850nm.
- 3. a kind of retina cell according to claim 2 repairs and regenerated LED light emitting device, which is characterized in that institute The centre of luminescence for stating red light fluorescent powder is Eu2+, luminous host is nitride.
- 4. a kind of retina cell according to claim 3 repairs and regenerated LED light emitting device, which is characterized in that institute Stating luminous host is A0.5+0.5yAlySi2-yN3Or B2-δD5N8Oδ, wherein A is Ca or Sr and 1.0 < y < 2.0, B Sr, Ba or Ca, D For Al or Si and 0≤δ < 1.0.
- 5. a kind of retina cell according to claim 4 repairs and regenerated LED light emitting device, which is characterized in that institute Stating red light fluorescent powder is (Ca1-zEuz)0.5+0.5yAlySi2-yN3, wherein 1.0 < y < 2.0,0 < z < 0.05.
- 6. according to a kind of described in any item retina cell's reparations of claim 2-5 and regenerated LED light emitting device, feature It is, the centre of luminescence of the far-red light fluorescent powder is Cr3+, luminous host is fluoride, oxygen fluoride or garnet structure High symmetry oxide.
- 7. a kind of retina cell according to claim 6 repairs and regenerated LED light emitting device, which is characterized in that institute State luminous host be fluoride when, be L3ExF6Or LLnF4, wherein L is K or Na, in E Al, Ga, Sc, Y, La, Gd or Lu Any, any one of Ln Sc, Y, La, Gd or Lu, and the sum of the atom number of E and the atom number of Cr be 1;It is M when the luminous host is oxygen fluoride3RO4FO, wherein M is Sr or Ca, and R is Al or Si;When the luminous host is garnet high symmetry oxide, it is selected from T3X5O12、Z3Al2(SiO4)3Or Y2CaMg2 (SiO4)3, wherein T is any one of Y, Ga, Lu or Tb, and X Al, Ga or Sc, Z is Ca or Mg.
- 8. a kind of retina cell according to claim 7 repairs and regenerated LED light emitting device, which is characterized in that institute Stating far-red light fluorescent powder is [L3(ExCr1-x)]F6, wherein 0 < x < 1.0, preparation method is as follows:(1) CrF is weighed according to the value of x3, LF and L3EF3, wherein LF and L3EF6Molar ratio be 0:1-3:1;(2) by CrF3It pours into polyvinyl fluoride reactor, hydrofluoric acid is added, stirs to dissolve;(3) LF is added into the product of step (2), L is added after LF dissolution3EF6, reactor is sealed, is stirred to react;(4) after reaction to step (3), stop stirring, reaction product is filtered, reacted and produced using acetone repeated flushing Object, until inspection does not measure acidity;(5) it takes reaction product to dry under 70 DEG C of vacuum conditions, obtains the far-red light fluorescent powder.
- 9. as a kind of described in any item repair for retina cell of claim 1-8 are answered with regenerated LED light emitting device With.
- 10. a kind of application repaired for retina cell with regenerated LED light emitting device according to claim 9, It is characterized in that, application of the LED light emitting device in display backlight source or lighting source.
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PCT/CN2018/112157 WO2020042318A1 (en) | 2018-08-30 | 2018-10-26 | Light-emitting device for retinal cell repair and regeneration and application thereof |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110518004A (en) * | 2019-08-29 | 2019-11-29 | 合肥工业大学智能制造技术研究院 | Special light source and lamps and lanterns suitable for diabetic retinopathy |
CN110531554A (en) * | 2019-08-29 | 2019-12-03 | 合肥工业大学智能制造技术研究院 | Promote display light source module group, display screen and the application of retina cell and optic element growth and reparation |
CN112186087A (en) * | 2020-08-28 | 2021-01-05 | 合肥工业大学 | Far-red light-near infrared light LED device preparation method and LED device |
CN112420902A (en) * | 2020-11-26 | 2021-02-26 | 欧普照明股份有限公司 | Light source module and lighting device comprising same |
CN113193100A (en) * | 2021-05-25 | 2021-07-30 | 鸿利智汇集团股份有限公司 | Promote infrared LED encapsulation of hela cell growth |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104871323A (en) * | 2012-12-28 | 2015-08-26 | 夏普株式会社 | Light emitting device |
CN106328795A (en) * | 2016-10-21 | 2017-01-11 | 电子科技大学 | Medical phototherapy pc-LEDs lamp |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090019677A (en) * | 2007-08-21 | 2009-02-25 | 삼성전기주식회사 | Oxy nitride phosphor, white light emitting device including oxy nitride phosphor and method for preparing phosphor |
CN102399552B (en) * | 2011-11-08 | 2014-07-30 | 杭州广陵科技开发有限公司 | Nitride red fluorescent powder for white light emitting diodes (LED) and preparation method thereof |
CN107676638A (en) * | 2017-08-17 | 2018-02-09 | 江苏脉锐光电科技有限公司 | A kind of LED light source |
CN108336208B (en) * | 2018-01-22 | 2020-04-14 | 暨南大学 | LED light source for spectrophotometer and preparation method thereof |
CN108424770B (en) * | 2018-01-29 | 2020-06-02 | 中国科学院长春光学精密机械与物理研究所 | Near-infrared fluorescent powder with broadband emission characteristic and preparation method and application thereof |
-
2018
- 2018-08-30 CN CN201811004355.2A patent/CN109192844A/en active Pending
- 2018-10-26 WO PCT/CN2018/112157 patent/WO2020042318A1/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104871323A (en) * | 2012-12-28 | 2015-08-26 | 夏普株式会社 | Light emitting device |
US20150357532A1 (en) * | 2012-12-28 | 2015-12-10 | Sharp Kabushiki Kaisha | Light emitting device |
CN106328795A (en) * | 2016-10-21 | 2017-01-11 | 电子科技大学 | Medical phototherapy pc-LEDs lamp |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110518004A (en) * | 2019-08-29 | 2019-11-29 | 合肥工业大学智能制造技术研究院 | Special light source and lamps and lanterns suitable for diabetic retinopathy |
CN110531554A (en) * | 2019-08-29 | 2019-12-03 | 合肥工业大学智能制造技术研究院 | Promote display light source module group, display screen and the application of retina cell and optic element growth and reparation |
WO2021035783A1 (en) * | 2019-08-29 | 2021-03-04 | 合肥工业大学智能制造技术研究院 | Display light source module for promoting growth and repair of retinal cells and visual neurons, display screen, and application |
WO2021035782A1 (en) * | 2019-08-29 | 2021-03-04 | 合肥工业大学智能制造技术研究院 | Special light source and light fixture suitable for diabetic retinopathy |
CN112186087A (en) * | 2020-08-28 | 2021-01-05 | 合肥工业大学 | Far-red light-near infrared light LED device preparation method and LED device |
CN112186087B (en) * | 2020-08-28 | 2021-09-28 | 合肥工业大学 | Far-red light-near infrared light LED device preparation method and LED device |
CN112420902A (en) * | 2020-11-26 | 2021-02-26 | 欧普照明股份有限公司 | Light source module and lighting device comprising same |
CN113193100A (en) * | 2021-05-25 | 2021-07-30 | 鸿利智汇集团股份有限公司 | Promote infrared LED encapsulation of hela cell growth |
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